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GSE58827: Dynamics of the Mouse Liver

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Results for Emx1_Emx2

Z-value: 1.28

Motif logo

Transcription factors associated with Emx1_Emx2

Gene Symbol Gene ID Gene Info
ENSMUSG00000033726.9 empty spiracles homeobox 1
ENSMUSG00000043969.5 empty spiracles homeobox 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Emx1mm39_v1_chr6_+_85164420_85164505-0.298.9e-02Click!
Emx2mm39_v1_chr19_+_59446804_59446883-0.289.9e-02Click!

Activity profile of Emx1_Emx2 motif

Sorted Z-values of Emx1_Emx2 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr19_+_39275518 21.54 ENSMUST00000003137.15
cytochrome P450, family 2, subfamily c, polypeptide 29
chr4_-_61972348 20.79 ENSMUST00000074018.4
major urinary protein 20
chr4_-_60070411 20.39 ENSMUST00000079697.10
ENSMUST00000125282.2
ENSMUST00000166098.8
major urinary protein 7
chr4_-_61357980 11.73 ENSMUST00000095049.5
major urinary protein 15
chr13_+_4486105 8.74 ENSMUST00000156277.2
aldo-keto reductase family 1, member C6
chr5_-_89605622 7.89 ENSMUST00000049209.13
vitamin D binding protein
chr19_-_39451509 7.81 ENSMUST00000035488.3
cytochrome P450, family 2, subfamily c, polypeptide 38
chr1_+_130754413 7.79 ENSMUST00000027675.14
ENSMUST00000133792.8
polymeric immunoglobulin receptor
chr5_-_87240405 7.35 ENSMUST00000132667.2
ENSMUST00000145617.8
ENSMUST00000094649.11
UDP glucuronosyltransferase 2 family, polypeptide B36
chr18_-_38999755 6.42 ENSMUST00000115582.8
ENSMUST00000236060.2
fibroblast growth factor 1
chr19_-_39637489 6.06 ENSMUST00000067328.7
cytochrome P450, family 2, subfamily c, polypeptide 67
chr16_+_22737128 5.33 ENSMUST00000170805.9
fetuin beta
chr16_+_22737227 5.19 ENSMUST00000231880.2
fetuin beta
chr16_+_22737050 5.08 ENSMUST00000231768.2
fetuin beta
chr2_-_157408239 5.08 ENSMUST00000109528.9
ENSMUST00000088494.3
bladder cancer associated protein
chr5_+_45650716 5.02 ENSMUST00000046122.11
leucine aminopeptidase 3
chr19_-_39801188 4.78 ENSMUST00000162507.2
ENSMUST00000160476.9
ENSMUST00000239028.2
cytochrome P450, family 2, subfamily c, polypeptide 40
chr15_+_100202079 4.30 ENSMUST00000230252.2
ENSMUST00000231166.2
methyltransferase like 7A1
chr1_-_139708906 4.30 ENSMUST00000111986.8
ENSMUST00000027612.11
ENSMUST00000111989.9
complement factor H-related 4
chr2_-_86180622 4.24 ENSMUST00000099894.5
ENSMUST00000213564.3
olfactory receptor 1055
chr1_-_139786421 4.24 ENSMUST00000194186.6
ENSMUST00000094489.5
ENSMUST00000239380.2
complement factor H-related 2
chr15_+_100202061 4.21 ENSMUST00000229574.2
ENSMUST00000229217.2
methyltransferase like 7A1
chr1_+_58152295 4.14 ENSMUST00000040999.14
ENSMUST00000162011.3
aldehyde oxidase 3
chr17_-_36343573 3.83 ENSMUST00000102678.5
histocompatibility 2, T region locus 23
chr15_+_100202021 3.81 ENSMUST00000230472.2
methyltransferase like 7A1
chr17_+_56312672 3.38 ENSMUST00000133998.8
MPN domain containing
chr9_+_21634779 3.35 ENSMUST00000034713.9
low density lipoprotein receptor
chr4_-_107975723 3.34 ENSMUST00000030340.15
sterol carrier protein 2, liver
chrX_-_8059597 3.28 ENSMUST00000143223.2
ENSMUST00000033509.15
phenylalkylamine Ca2+ antagonist (emopamil) binding protein
chr5_-_87682972 2.89 ENSMUST00000120150.2
sulfotransferase family 1B, member 1
chr14_+_55797468 2.73 ENSMUST00000147981.2
ENSMUST00000133256.8
DDB1 and CUL4 associated factor 11
chr2_-_17465410 2.56 ENSMUST00000145492.2
nebulette
chr6_+_129510331 2.55 ENSMUST00000204956.2
ENSMUST00000204639.2
gamma-aminobutyric acid (GABA) A receptor-associated protein-like 1
chr14_+_118374511 2.27 ENSMUST00000022728.4
G protein-coupled receptor 180
chr6_+_129510117 2.22 ENSMUST00000032264.9
gamma-aminobutyric acid (GABA) A receptor-associated protein-like 1
chr6_+_129510145 2.13 ENSMUST00000204487.3
gamma-aminobutyric acid (GABA) A receptor-associated protein-like 1
chr7_-_101494472 2.12 ENSMUST00000211566.2
ENSMUST00000094141.7
ENSMUST00000209329.2
folate receptor 2 (fetal)
chr9_+_78099229 2.10 ENSMUST00000034903.7
glutathione S-transferase, alpha 4
chr16_+_11224481 2.09 ENSMUST00000122168.8
sorting nexin 29
chr16_-_43836681 1.95 ENSMUST00000036174.10
GRAM domain containing 1C
chr5_+_104350475 1.87 ENSMUST00000066708.7
dentin matrix protein 1
chr4_-_150998857 1.80 ENSMUST00000105675.8
Parkinson disease (autosomal recessive, early onset) 7
chr1_-_162726234 1.77 ENSMUST00000111510.8
ENSMUST00000045902.13
flavin containing monooxygenase 2
chr11_-_54140462 1.72 ENSMUST00000019060.6
colony stimulating factor 2 (granulocyte-macrophage)
chr6_+_41248311 1.72 ENSMUST00000103281.3
T cell receptor beta, variable 29
chr7_+_126380655 1.70 ENSMUST00000172352.8
ENSMUST00000094037.5
T-box 6
chr11_+_109434519 1.61 ENSMUST00000106696.2
arylsulfatase G
chr18_-_66135683 1.60 ENSMUST00000120461.9
ENSMUST00000048260.15
ENSMUST00000236866.2
lectin, mannose-binding, 1
chr13_-_4659120 1.60 ENSMUST00000091848.7
ENSMUST00000110691.10
aldo-keto reductase family 1, member E1
chr18_-_39000056 1.56 ENSMUST00000236630.2
ENSMUST00000237356.2
fibroblast growth factor 1
chr2_-_12424212 1.54 ENSMUST00000124603.8
ENSMUST00000129993.3
ENSMUST00000028105.13
MINDY lysine 48 deubiquitinase 3
chr2_+_144435974 1.47 ENSMUST00000136628.2
small integral membrane protein 26
chr12_+_84332006 1.45 ENSMUST00000123614.8
ENSMUST00000147363.8
ENSMUST00000135001.8
ENSMUST00000146377.8
prostaglandin reductase 2
chr17_+_79919267 1.41 ENSMUST00000223924.2
regulator of microtubule dynamics 2
chr4_-_82423944 1.41 ENSMUST00000107248.8
ENSMUST00000107247.8
nuclear factor I/B
chr10_+_128158413 1.40 ENSMUST00000219836.2
canopy FGF signaling regulator 2
chr11_+_99755302 1.38 ENSMUST00000092694.4
predicted gene 11559
chr11_-_49004584 1.37 ENSMUST00000203007.2
olfactory receptor 1396
chr17_+_15163446 1.36 ENSMUST00000052691.9
RIKEN cDNA 1600012H06 gene
chr10_-_85847697 1.26 ENSMUST00000105304.2
ENSMUST00000061699.12
BPI fold containing family C
chr12_-_55045887 1.25 ENSMUST00000173529.2
bromodomain adjacent to zinc finger domain 1A
chr10_+_128158328 1.23 ENSMUST00000219037.2
ENSMUST00000026446.4
canopy FGF signaling regulator 2
chr11_-_12362136 1.20 ENSMUST00000174874.8
cordon-bleu WH2 repeat
chr18_-_73887528 1.20 ENSMUST00000041138.3
elaC ribonuclease Z 1
chr9_+_50466127 1.18 ENSMUST00000213916.2
interleukin 18
chr1_-_63215952 1.17 ENSMUST00000185412.7
ENSMUST00000027111.15
ENSMUST00000189664.2
NADH:ubiquinone oxidoreductase core subunit S1
chr14_+_14210932 1.12 ENSMUST00000022271.14
acyl-Coenzyme A oxidase 2, branched chain
chr2_-_89555356 1.10 ENSMUST00000216203.2
ENSMUST00000213196.2
olfactory receptor 1252
chrX_-_159777661 1.10 ENSMUST00000087104.11
cyclin-dependent kinase-like 5
chr15_-_103473481 1.08 ENSMUST00000228060.2
ENSMUST00000228895.2
ENSMUST00000023134.5
glycosylation dependent cell adhesion molecule 1
chr10_-_8632519 1.07 ENSMUST00000212869.2
SAM and SH3 domain containing 1
chr2_-_119493237 1.05 ENSMUST00000028768.2
ENSMUST00000110801.8
ENSMUST00000110802.8
NADH:ubiquinone oxidoreductase complex assembly factor 1
chr13_-_24118139 1.05 ENSMUST00000052776.4
H2B clustered histone 1
chr17_-_40630096 1.05 ENSMUST00000026498.5
cysteine-rich secretory protein 1
chr5_-_3697806 1.04 ENSMUST00000119783.2
ENSMUST00000007559.15
GATA zinc finger domain containing 1
chr11_+_17207558 1.03 ENSMUST00000000594.9
ENSMUST00000156784.2
C1D nuclear receptor co-repressor
chr2_+_69619991 1.01 ENSMUST00000112266.8
phosphatase, orphan 2
chr8_+_45960804 1.01 ENSMUST00000067065.14
ENSMUST00000124544.8
ENSMUST00000138049.9
ENSMUST00000132139.9
sorbin and SH3 domain containing 2
chr17_+_29493049 1.00 ENSMUST00000149405.4
cDNA sequence BC004004
chr10_-_128885867 0.99 ENSMUST00000216460.2
olfactory receptor 765
chr17_+_15163466 0.93 ENSMUST00000164837.3
ENSMUST00000174004.2
RIKEN cDNA 1600012H06 gene
chr2_+_36575800 0.92 ENSMUST00000213258.2
olfactory receptor 346
chr1_-_158183894 0.91 ENSMUST00000004133.11
bone morphogenic protein/retinoic acid inducible neural-specific 2
chr4_+_138606671 0.91 ENSMUST00000105804.2
phospholipase A2, group IIE
chrM_+_11735 0.91 ENSMUST00000082418.1
mitochondrially encoded NADH dehydrogenase 5
chr10_-_81243475 0.91 ENSMUST00000140916.8
nuclear factor I/C
chr17_-_15163362 0.90 ENSMUST00000238668.2
ENSMUST00000228330.2
WD repeat domain 27
chrX_-_55643429 0.90 ENSMUST00000059899.3
membrane magnesium transporter 1
chr1_-_37535170 0.89 ENSMUST00000148047.2
mannoside acetylglucosaminyltransferase 4, isoenzyme A
chr15_-_5093222 0.89 ENSMUST00000110689.5
complement component 7
chr8_+_45960931 0.88 ENSMUST00000171337.10
ENSMUST00000067107.15
sorbin and SH3 domain containing 2
chr1_-_162726053 0.88 ENSMUST00000143123.3
flavin containing monooxygenase 2
chr17_+_29493113 0.87 ENSMUST00000234326.2
ENSMUST00000235117.2
cDNA sequence BC004004
chr15_+_99192968 0.86 ENSMUST00000128352.8
ENSMUST00000145482.8
pre-mRNA processing factor 40B
chr2_-_12424189 0.86 ENSMUST00000124515.2
MINDY lysine 48 deubiquitinase 3
chr17_-_45910529 0.85 ENSMUST00000171847.8
ENSMUST00000166633.8
ENSMUST00000169729.8
solute carrier family 29 (nucleoside transporters), member 1
chr10_-_39039790 0.85 ENSMUST00000076713.6
cellular communication network factor 6
chr7_+_129193581 0.84 ENSMUST00000084519.7
WD repeat domain 11
chr8_+_72973560 0.84 ENSMUST00000003123.10
family with sequence similarity 32, member A
chr3_+_108479015 0.80 ENSMUST00000143054.2
TATA-box binding protein associated factor 13
chr13_-_43634695 0.79 ENSMUST00000144326.4
RAN binding protein 9
chr4_+_150999019 0.78 ENSMUST00000135169.8
tumor necrosis factor receptor superfamily, member 9
chr14_-_51433380 0.77 ENSMUST00000051274.2
angiogenin, ribonuclease A family, member 2
chr2_-_155772110 0.76 ENSMUST00000109636.11
ENSMUST00000109631.8
ubiquinol-cytochrome c reductase complex assembly factor 1
chr13_+_19374502 0.75 ENSMUST00000198330.2
ENSMUST00000103555.3
T cell receptor gamma, variable 6
chr8_-_126625029 0.74 ENSMUST00000047239.13
ENSMUST00000131127.3
pecanex homolog 2
chr1_-_63215812 0.73 ENSMUST00000185847.2
ENSMUST00000185732.7
ENSMUST00000188370.7
ENSMUST00000168099.9
NADH:ubiquinone oxidoreductase core subunit S1
chr6_-_57512355 0.73 ENSMUST00000042766.6
protein phosphatase 1K (PP2C domain containing)
chr12_-_84664001 0.72 ENSMUST00000221070.2
ENSMUST00000021666.6
ENSMUST00000223107.2
ATP-binding cassette, sub-family D (ALD), member 4
chr17_+_29493157 0.72 ENSMUST00000234234.2
cDNA sequence BC004004
chr4_+_127019826 0.71 ENSMUST00000094712.5
transmembrane protein 35B
chr9_-_15212745 0.71 ENSMUST00000217042.2
RIKEN cDNA 4931406C07 gene
chr4_-_149184259 0.71 ENSMUST00000103217.11
peroxisomal biogenesis factor 14
chr8_-_22396428 0.71 ENSMUST00000051965.5
defensin beta 11
chr12_+_74044435 0.71 ENSMUST00000221220.2
synaptotagmin XVI
chr7_+_79896121 0.69 ENSMUST00000058266.9
tubulin tyrosine ligase-like family, member 13
chr7_-_121700958 0.68 ENSMUST00000139456.2
ENSMUST00000106471.9
ENSMUST00000123296.8
ENSMUST00000033157.10
NADH:ubiquinone oxidoreductase subunit AB1
chr16_-_92155762 0.67 ENSMUST00000166707.3
potassium voltage-gated channel, Isk-related subfamily, member 1
chr2_+_36263531 0.67 ENSMUST00000072114.4
ENSMUST00000217511.2
olfactory receptor 338
chr4_+_150321272 0.66 ENSMUST00000080926.13
enolase 1, alpha non-neuron
chr5_-_139330906 0.65 ENSMUST00000049630.13
cytochrome c oxidase assembly protein 19
chr14_-_96756503 0.64 ENSMUST00000022666.9
kelch-like 1
chr15_-_36496880 0.63 ENSMUST00000228601.2
ENSMUST00000057486.9
ankyrin repeat domain 46
chr6_-_123830422 0.63 ENSMUST00000162046.3
vomeronasal 2, receptor 25
chr6_-_13607963 0.63 ENSMUST00000031554.9
ENSMUST00000149123.3
transmembrane protein 168
chr11_+_73262072 0.62 ENSMUST00000078952.9
ENSMUST00000120401.9
ENSMUST00000170592.4
olfactory receptor 376
chr8_-_10027650 0.62 ENSMUST00000170033.2
ligase IV, DNA, ATP-dependent
chr7_+_11770679 0.62 ENSMUST00000228213.2
ENSMUST00000226525.2
ENSMUST00000227320.2
vomeronasal 1 receptor 77
chrX_-_158921370 0.61 ENSMUST00000033662.9
pyruvate dehydrogenase E1 alpha 1
chr4_+_118818775 0.61 ENSMUST00000058651.5
L-amino acid oxidase 1
chr5_-_118382926 0.60 ENSMUST00000117177.8
ENSMUST00000133372.2
ENSMUST00000154786.8
ENSMUST00000121369.8
ring finger protein, transmembrane 2
chr17_+_44337566 0.60 ENSMUST00000229939.2
regulator of calcineurin 2
chr19_-_33728759 0.60 ENSMUST00000147153.4
lipase, member O2
chr10_-_67748461 0.60 ENSMUST00000064656.8
zinc finger protein 365
chr4_-_4077510 0.59 ENSMUST00000108383.2
short chain dehydrogenase/reductase family 16C, member 6
chr6_+_114435480 0.58 ENSMUST00000160780.2
histamine receptor H1
chr19_+_44481901 0.57 ENSMUST00000041163.5
wingless-type MMTV integration site family, member 8B
chr4_-_117622747 0.56 ENSMUST00000062747.6
Kruppel-like factor 17
chr12_-_114186874 0.56 ENSMUST00000103477.4
ENSMUST00000192499.3
immunoglobulin heavy variable 7-4
chr6_-_144155197 0.56 ENSMUST00000038815.14
ENSMUST00000111749.8
ENSMUST00000170367.9
SRY (sex determining region Y)-box 5
chr2_+_151336197 0.55 ENSMUST00000028949.16
ENSMUST00000103160.5
NSFL1 (p97) cofactor (p47)
chr12_+_37930305 0.55 ENSMUST00000220990.2
diacylglycerol kinase, beta
chrM_+_2743 0.55 ENSMUST00000082392.1
mitochondrially encoded NADH dehydrogenase 1
chr12_+_80509869 0.54 ENSMUST00000038185.10
exonuclease 3'-5' domain containing 2
chr3_+_127426783 0.54 ENSMUST00000029587.9
neurogenin 2
chr13_-_99653045 0.53 ENSMUST00000064762.6
microtubule-associated protein 1B
chr1_+_88234454 0.53 ENSMUST00000040210.14
transient receptor potential cation channel, subfamily M, member 8
chr19_-_12313274 0.53 ENSMUST00000208398.3
olfactory receptor 1438, pseudogene 1
chr13_+_19369097 0.53 ENSMUST00000103554.5
T cell receptor gamma, variable 4
chr7_-_103191924 0.53 ENSMUST00000214269.3
olfactory receptor 612
chr8_+_22329942 0.52 ENSMUST00000006745.4
defensin beta 2
chr16_+_88525719 0.52 ENSMUST00000060494.8
keratin associated protein 13-1
chr16_-_65359406 0.50 ENSMUST00000231259.2
charged multivesicular body protein 2B
chr6_+_124001527 0.50 ENSMUST00000032238.5
vomeronasal 2, receptor 26
chr2_-_155771938 0.50 ENSMUST00000152766.8
ENSMUST00000139232.8
ENSMUST00000109632.8
ENSMUST00000006036.13
ENSMUST00000142655.2
ENSMUST00000159238.2
ubiquinol-cytochrome c reductase complex assembly factor 1
chr3_-_75359125 0.49 ENSMUST00000204341.3
WD repeat domain 49
chr2_+_74552322 0.48 ENSMUST00000047904.4
homeobox D4
chr12_-_11485639 0.48 ENSMUST00000220506.2
visinin-like 1
chr6_-_144993362 0.48 ENSMUST00000149769.6
branched chain aminotransferase 1, cytosolic
chr17_+_37977879 0.47 ENSMUST00000215811.2
olfactory receptor 118
chr16_-_63684425 0.46 ENSMUST00000232049.2
Eph receptor A3
chr10_-_40134104 0.46 ENSMUST00000217141.2
general transcription factor IIIC, polypeptide 6, alpha
chr6_-_144155167 0.45 ENSMUST00000077160.12
SRY (sex determining region Y)-box 5
chr7_-_78432774 0.45 ENSMUST00000032841.7
mitochondrial ribosomal protein L46
chr7_+_126575781 0.45 ENSMUST00000206450.2
ENSMUST00000205830.2
CDP-diacylglycerol--inositol 3-phosphatidyltransferase (phosphatidylinositol synthase)
chr4_+_126503611 0.44 ENSMUST00000097886.4
ENSMUST00000164362.2
RIKEN cDNA 5730409E04Rik gene
chr14_+_65504067 0.44 ENSMUST00000224629.2
F-box protein 16
chr4_+_150321142 0.44 ENSMUST00000150175.8
enolase 1, alpha non-neuron
chr6_+_67532481 0.44 ENSMUST00000103302.3
immunoglobulin kappa chain variable 2-137
chr2_+_111144362 0.43 ENSMUST00000219291.2
olfactory receptor 1280
chr2_-_148692834 0.43 ENSMUST00000028937.3
cystatin domain containing 2
chr7_+_23752679 0.42 ENSMUST00000236959.2
vomeronasal 1 receptor 183
chr9_-_14411690 0.42 ENSMUST00000115647.3
lysine (K)-specific demethylase 4D
chr2_+_113116075 0.42 ENSMUST00000040856.3
transmembrane and coiled-coil domains 5B
chr12_+_87490666 0.42 ENSMUST00000161023.8
ENSMUST00000160488.8
ENSMUST00000077462.8
ENSMUST00000160880.2
SRA stem-loop interacting RNA binding protein
chr14_+_53574579 0.42 ENSMUST00000179580.3
T cell receptor alpha variable 13N-3
chr6_+_41512010 0.41 ENSMUST00000103288.2
T cell receptor beta joining 1-5
chr6_-_144993451 0.41 ENSMUST00000123930.8
branched chain aminotransferase 1, cytosolic
chr13_-_120676749 0.41 ENSMUST00000177561.2
predicted gene, 21762
chr2_-_73410632 0.41 ENSMUST00000028515.4
cholinergic receptor, nicotinic, alpha polypeptide 1 (muscle)
chr2_-_90054837 0.41 ENSMUST00000213994.3
olfactory receptor 1506
chr12_+_71021395 0.40 ENSMUST00000160027.8
ENSMUST00000160864.8
proteasome subunit alpha 3
chr8_+_55053809 0.40 ENSMUST00000033917.7
spermatogenesis associated 4
chr3_+_92864693 0.40 ENSMUST00000059053.11
late cornified envelope 3D
chr9_+_103917821 0.40 ENSMUST00000216593.2
ENSMUST00000147249.3
nephronophthisis 3 (adolescent)
predicted gene 28305
chrX_-_125723491 0.40 ENSMUST00000081074.5
RIKEN cDNA 4932411N23 gene
chr6_+_134617903 0.40 ENSMUST00000062755.10
BLOC-1 related complex subunit 5
chr4_+_146033882 0.40 ENSMUST00000105730.2
ENSMUST00000091878.6
zinc finger protein 987
chr4_+_126156118 0.40 ENSMUST00000030660.9
trafficking protein particle complex 3
chr13_+_55932369 0.39 ENSMUST00000021961.12
cation channel, sperm associated 3
chr1_-_84816379 0.39 ENSMUST00000187818.2
thyroid hormone receptor interactor 12
chr7_-_29553079 0.39 ENSMUST00000108223.8
zinc finger protein 940
chr9_-_14411778 0.38 ENSMUST00000058796.7
lysine (K)-specific demethylase 4D
chr14_+_25979825 0.38 ENSMUST00000173580.8
double homeobox B-like 1
chr15_+_100320028 0.37 ENSMUST00000132119.2
predicted gene 5475
chr8_+_45960855 0.37 ENSMUST00000141039.8
sorbin and SH3 domain containing 2
chr3_-_96359622 0.37 ENSMUST00000093126.11
ENSMUST00000098841.4
cDNA sequence BC107364
chr11_+_21041291 0.37 ENSMUST00000093290.12
pellino 1
chr6_+_86986213 0.36 ENSMUST00000120240.8
NFU1 iron-sulfur cluster scaffold
chr7_+_107497109 0.34 ENSMUST00000209670.4
ENSMUST00000216937.3
olfactory receptor 472

Network of associatons between targets according to the STRING database.

First level regulatory network of Emx1_Emx2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
3.5 20.8 GO:0008355 olfactory learning(GO:0008355)
2.9 8.7 GO:0009753 response to jasmonic acid(GO:0009753) cellular response to jasmonic acid stimulus(GO:0071395)
2.6 7.8 GO:0002386 immune response in mucosal-associated lymphoid tissue(GO:0002386) immunoglobulin transcytosis in epithelial cells(GO:0002414)
1.3 3.8 GO:2000566 antigen processing and presentation of endogenous peptide antigen via MHC class Ib(GO:0002476) positive regulation of CD8-positive, alpha-beta T cell proliferation(GO:2000566)
1.1 37.9 GO:0019373 epoxygenase P450 pathway(GO:0019373)
1.1 8.0 GO:1901509 regulation of endothelial tube morphogenesis(GO:1901509)
0.8 3.4 GO:1905167 regulation of phosphatidylcholine catabolic process(GO:0010899) positive regulation of lysosomal protein catabolic process(GO:1905167)
0.8 3.3 GO:1901373 positive regulation of intracellular lipid transport(GO:0032379) positive regulation of intracellular sterol transport(GO:0032382) positive regulation of intracellular cholesterol transport(GO:0032385) lipid hydroperoxide transport(GO:1901373)
0.8 4.1 GO:0009115 xanthine catabolic process(GO:0009115)
0.5 2.9 GO:0006068 ethanol catabolic process(GO:0006068)
0.5 1.9 GO:0070173 regulation of enamel mineralization(GO:0070173)
0.5 1.8 GO:1903122 enzyme active site formation via L-cysteine sulfinic acid(GO:0018323) primary alcohol biosynthetic process(GO:0034309) cellular response to glyoxal(GO:0036471) glycolate biosynthetic process(GO:0046295) negative regulation of TRAIL-activated apoptotic signaling pathway(GO:1903122) regulation of pyrroline-5-carboxylate reductase activity(GO:1903167) positive regulation of pyrroline-5-carboxylate reductase activity(GO:1903168) regulation of tyrosine 3-monooxygenase activity(GO:1903176) positive regulation of tyrosine 3-monooxygenase activity(GO:1903178) L-dopa metabolic process(GO:1903184) L-dopa biosynthetic process(GO:1903185) glyoxal metabolic process(GO:1903189) regulation of L-dopa biosynthetic process(GO:1903195) positive regulation of L-dopa biosynthetic process(GO:1903197) regulation of L-dopa decarboxylase activity(GO:1903198) positive regulation of L-dopa decarboxylase activity(GO:1903200) positive regulation of cellular amino acid biosynthetic process(GO:2000284)
0.4 2.7 GO:0072592 oxygen metabolic process(GO:0072592)
0.4 6.9 GO:0006995 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.4 1.7 GO:0032747 positive regulation of interleukin-23 production(GO:0032747)
0.4 2.6 GO:0045716 positive regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045716)
0.4 7.9 GO:0042359 vitamin D metabolic process(GO:0042359)
0.4 1.4 GO:2000795 negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
0.3 1.2 GO:0042231 interleukin-13 biosynthetic process(GO:0042231)
0.3 15.6 GO:0007339 binding of sperm to zona pellucida(GO:0007339)
0.3 0.8 GO:2001034 positive regulation of double-strand break repair via nonhomologous end joining(GO:2001034)
0.2 0.7 GO:0016561 protein import into peroxisome matrix, translocation(GO:0016561)
0.2 2.6 GO:1901727 positive regulation of histone deacetylase activity(GO:1901727)
0.2 1.1 GO:1902498 regulation of protein autoubiquitination(GO:1902498)
0.2 1.7 GO:0014043 negative regulation of neuron maturation(GO:0014043)
0.2 1.2 GO:0042780 tRNA 3'-end processing(GO:0042780)
0.2 1.1 GO:0033540 fatty acid beta-oxidation using acyl-CoA oxidase(GO:0033540)
0.2 1.2 GO:0001757 somite specification(GO:0001757)
0.1 0.6 GO:0033566 gamma-tubulin complex localization(GO:0033566)
0.1 1.0 GO:0060164 regulation of timing of neuron differentiation(GO:0060164)
0.1 5.1 GO:0030262 apoptotic nuclear changes(GO:0030262)
0.1 0.8 GO:0015862 uridine transport(GO:0015862)
0.1 0.7 GO:0009235 cobalamin metabolic process(GO:0009235)
0.1 0.6 GO:0046341 CDP-diacylglycerol metabolic process(GO:0046341)
0.1 0.9 GO:0009099 branched-chain amino acid biosynthetic process(GO:0009082) leucine biosynthetic process(GO:0009098) valine biosynthetic process(GO:0009099)
0.1 2.1 GO:0015884 folic acid transport(GO:0015884)
0.1 1.3 GO:0034551 respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551)
0.1 0.4 GO:0000957 mitochondrial RNA catabolic process(GO:0000957) regulation of mitochondrial RNA catabolic process(GO:0000960)
0.1 0.6 GO:0097680 double-strand break repair via classical nonhomologous end joining(GO:0097680)
0.1 0.6 GO:0071421 manganese ion transmembrane transport(GO:0071421)
0.1 0.8 GO:2001183 negative regulation of interleukin-12 secretion(GO:2001183)
0.1 0.3 GO:0019858 cytosine metabolic process(GO:0019858)
0.1 0.6 GO:0061732 mitochondrial acetyl-CoA biosynthetic process from pyruvate(GO:0061732)
0.1 0.7 GO:0009249 protein lipoylation(GO:0009249)
0.1 0.6 GO:0097211 response to gonadotropin-releasing hormone(GO:0097210) cellular response to gonadotropin-releasing hormone(GO:0097211)
0.1 0.4 GO:1902310 positive regulation of peptidyl-serine dephosphorylation(GO:1902310)
0.1 0.2 GO:0097156 fasciculation of motor neuron axon(GO:0097156)
0.1 2.4 GO:0071108 protein K48-linked deubiquitination(GO:0071108)
0.1 0.9 GO:0006824 cobalt ion transport(GO:0006824)
0.1 0.2 GO:1903487 regulation of lactation(GO:1903487)
0.1 0.4 GO:0035469 determination of pancreatic left/right asymmetry(GO:0035469) maintenance of organ identity(GO:0048496)
0.1 0.5 GO:0050955 thermoception(GO:0050955)
0.1 0.5 GO:0014719 skeletal muscle satellite cell activation(GO:0014719)
0.0 0.7 GO:0031468 nuclear envelope reassembly(GO:0031468)
0.0 0.0 GO:0060974 cell migration involved in heart formation(GO:0060974)
0.0 3.3 GO:0006695 cholesterol biosynthetic process(GO:0006695)
0.0 0.2 GO:0046013 T cell homeostatic proliferation(GO:0001777) regulation of T cell homeostatic proliferation(GO:0046013)
0.0 2.8 GO:0042773 ATP synthesis coupled electron transport(GO:0042773)
0.0 0.7 GO:1901387 positive regulation of voltage-gated calcium channel activity(GO:1901387)
0.0 0.9 GO:0034374 low-density lipoprotein particle remodeling(GO:0034374)
0.0 0.2 GO:0032690 negative regulation of interleukin-1 alpha production(GO:0032690) negative regulation of interleukin-1 alpha secretion(GO:0050712)
0.0 0.1 GO:2001200 positive regulation of dendritic cell differentiation(GO:2001200)
0.0 0.9 GO:0070050 neuron cellular homeostasis(GO:0070050)
0.0 0.2 GO:0097394 post-embryonic appendage morphogenesis(GO:0035120) post-embryonic limb morphogenesis(GO:0035127) post-embryonic forelimb morphogenesis(GO:0035128) telomeric repeat-containing RNA transcription(GO:0097393) telomeric repeat-containing RNA transcription from RNA pol II promoter(GO:0097394) regulation of telomeric RNA transcription from RNA pol II promoter(GO:1901580) negative regulation of telomeric RNA transcription from RNA pol II promoter(GO:1901581) positive regulation of telomeric RNA transcription from RNA pol II promoter(GO:1901582)
0.0 0.4 GO:0008063 Toll signaling pathway(GO:0008063)
0.0 0.6 GO:0033617 mitochondrial respiratory chain complex IV assembly(GO:0033617)
0.0 0.9 GO:0006883 cellular sodium ion homeostasis(GO:0006883)
0.0 0.1 GO:0007208 phospholipase C-activating serotonin receptor signaling pathway(GO:0007208) positive regulation of phosphatidylinositol biosynthetic process(GO:0010513)
0.0 0.3 GO:0048743 positive regulation of skeletal muscle fiber development(GO:0048743)
0.0 0.3 GO:0031914 negative regulation of synaptic plasticity(GO:0031914)
0.0 2.3 GO:0061049 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.0 0.1 GO:0035038 female pronucleus assembly(GO:0035038)
0.0 3.3 GO:0019236 response to pheromone(GO:0019236)
0.0 0.2 GO:0046116 queuosine biosynthetic process(GO:0008616) queuosine metabolic process(GO:0046116)
0.0 0.7 GO:0000729 DNA double-strand break processing(GO:0000729)
0.0 1.0 GO:0000460 maturation of 5.8S rRNA(GO:0000460)
0.0 0.1 GO:0060300 regulation of cytokine activity(GO:0060300)
0.0 0.5 GO:0061162 establishment of monopolar cell polarity(GO:0061162)
0.0 0.6 GO:0007614 short-term memory(GO:0007614)
0.0 0.8 GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.0 1.6 GO:0007029 endoplasmic reticulum organization(GO:0007029)
0.0 0.2 GO:0006228 UTP biosynthetic process(GO:0006228)
0.0 0.1 GO:0070562 regulation of vitamin D receptor signaling pathway(GO:0070562)
0.0 0.6 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.0 0.5 GO:0033194 response to hydroperoxide(GO:0033194)
0.0 0.4 GO:0016226 iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
0.0 1.1 GO:0045773 positive regulation of axon extension(GO:0045773)
0.0 0.3 GO:0046855 inositol phosphate dephosphorylation(GO:0046855)
0.0 0.3 GO:0033141 positive regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033141)
0.0 0.9 GO:0071300 cellular response to retinoic acid(GO:0071300)
0.0 1.3 GO:0031497 chromatin assembly(GO:0031497)
0.0 0.4 GO:0048240 sperm capacitation(GO:0048240)
0.0 0.6 GO:0007628 adult walking behavior(GO:0007628)
0.0 0.5 GO:0035774 positive regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0035774)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 3.4 GO:1990666 PCSK9-LDLR complex(GO:1990666)
0.3 1.3 GO:0008623 CHRAC(GO:0008623)
0.3 3.8 GO:0042612 MHC class I protein complex(GO:0042612)
0.3 3.3 GO:0031315 extrinsic component of mitochondrial outer membrane(GO:0031315)
0.2 7.0 GO:0000421 autophagosome membrane(GO:0000421)
0.2 0.7 GO:1990730 VCP-NSFL1C complex(GO:1990730)
0.2 0.7 GO:1990429 Pex17p-Pex14p docking complex(GO:1990415) peroxisomal importomer complex(GO:1990429)
0.2 7.8 GO:0055038 recycling endosome membrane(GO:0055038)
0.1 1.2 GO:1990357 terminal web(GO:1990357)
0.1 12.2 GO:0005811 lipid particle(GO:0005811)
0.1 0.6 GO:0005958 DNA-dependent protein kinase-DNA ligase 4 complex(GO:0005958) DNA ligase IV complex(GO:0032807)
0.1 0.4 GO:0097543 ciliary inversin compartment(GO:0097543)
0.1 0.9 GO:0005579 membrane attack complex(GO:0005579)
0.1 4.9 GO:0005747 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.1 0.6 GO:0045254 pyruvate dehydrogenase complex(GO:0045254)
0.1 1.6 GO:0033655 host cell cytoplasm(GO:0030430) host cell cytoplasm part(GO:0033655)
0.1 1.1 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.1 1.1 GO:0044294 dendritic growth cone(GO:0044294)
0.1 0.9 GO:0072546 ER membrane protein complex(GO:0072546)
0.1 1.4 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.1 2.5 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.1 1.5 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.0 0.4 GO:0098574 cytoplasmic side of lysosomal membrane(GO:0098574)
0.0 0.3 GO:0044305 calyx of Held(GO:0044305)
0.0 1.0 GO:0000178 exosome (RNase complex)(GO:0000178)
0.0 0.5 GO:0000815 ESCRT III complex(GO:0000815)
0.0 7.6 GO:0030496 midbody(GO:0030496)
0.0 0.2 GO:1990707 subtelomeric heterochromatin(GO:1990421) nuclear subtelomeric heterochromatin(GO:1990707)
0.0 0.9 GO:0071004 U2-type prespliceosome(GO:0071004)
0.0 0.4 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.0 0.4 GO:0036128 CatSper complex(GO:0036128)
0.0 0.8 GO:0005721 pericentric heterochromatin(GO:0005721)
0.0 0.6 GO:0005922 connexon complex(GO:0005922)
0.0 0.5 GO:0043196 varicosity(GO:0043196)
0.0 0.9 GO:0070469 respiratory chain(GO:0070469)
0.0 0.6 GO:0000930 gamma-tubulin complex(GO:0000930)
0.0 0.4 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.0 0.0 GO:0016939 kinesin II complex(GO:0016939)
0.0 0.4 GO:0030008 TRAPP complex(GO:0030008)
0.0 0.1 GO:0034388 Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
0.0 6.7 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.0 0.3 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0 0.5 GO:0001533 cornified envelope(GO:0001533)
0.0 0.1 GO:0071547 piP-body(GO:0071547)
0.0 3.3 GO:0072562 blood microparticle(GO:0072562)
0.0 0.1 GO:0005726 perichromatin fibrils(GO:0005726)
0.0 28.0 GO:0005783 endoplasmic reticulum(GO:0005783)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
4.9 29.4 GO:0034875 oxidoreductase activity, acting on CH or CH2 groups, quinone or similar compound as acceptor(GO:0033695) caffeine oxidase activity(GO:0034875)
4.2 20.8 GO:0005186 pheromone activity(GO:0005186)
2.9 8.7 GO:0047006 17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity(GO:0047006)
2.0 7.9 GO:1902271 D3 vitamins binding(GO:1902271)
0.8 3.3 GO:0033814 propanoyl-CoA C-acyltransferase activity(GO:0033814) propionyl-CoA C2-trimethyltridecanoyltransferase activity(GO:0050632) phosphatidylethanolamine transporter activity(GO:1904121)
0.8 4.1 GO:0016726 aldehyde oxidase activity(GO:0004031) xanthine dehydrogenase activity(GO:0004854) oxidoreductase activity, acting on the aldehyde or oxo group of donors, oxygen as acceptor(GO:0016623) oxidoreductase activity, acting on CH or CH2 groups, NAD or NADP as acceptor(GO:0016726) molybdenum ion binding(GO:0030151)
0.7 2.9 GO:0004062 aryl sulfotransferase activity(GO:0004062)
0.7 15.6 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.6 7.8 GO:0019763 immunoglobulin receptor activity(GO:0019763)
0.5 3.3 GO:0004769 steroid delta-isomerase activity(GO:0004769)
0.5 1.8 GO:0036478 tyrosine 3-monooxygenase activator activity(GO:0036470) L-dopa decarboxylase activator activity(GO:0036478)
0.4 3.3 GO:0030229 very-low-density lipoprotein particle receptor activity(GO:0030229)
0.4 2.4 GO:0016807 cysteine-type carboxypeptidase activity(GO:0016807) cysteine-type exopeptidase activity(GO:0070004)
0.4 8.0 GO:0044548 S100 protein binding(GO:0044548)
0.4 1.4 GO:0047522 13-prostaglandin reductase activity(GO:0036132) 15-oxoprostaglandin 13-oxidase activity(GO:0047522)
0.3 6.9 GO:0030957 Tat protein binding(GO:0030957)
0.3 8.6 GO:0008392 arachidonic acid epoxygenase activity(GO:0008392)
0.3 3.8 GO:0030881 beta-2-microglobulin binding(GO:0030881)
0.3 1.0 GO:0033883 pyridoxal phosphatase activity(GO:0033883)
0.2 2.7 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.2 0.7 GO:0031177 phosphopantetheine binding(GO:0031177)
0.2 0.6 GO:0001716 L-amino-acid oxidase activity(GO:0001716)
0.2 0.6 GO:0004968 gonadotropin-releasing hormone receptor activity(GO:0004968)
0.2 0.6 GO:0003881 CDP-diacylglycerol-inositol 3-phosphatidyltransferase activity(GO:0003881)
0.2 2.1 GO:0051870 methotrexate binding(GO:0051870)
0.2 7.4 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.1 0.6 GO:0051381 histamine binding(GO:0051381)
0.1 4.4 GO:0008137 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.1 1.1 GO:0016725 oxidoreductase activity, acting on CH or CH2 groups(GO:0016725)
0.1 1.1 GO:0043199 sulfate binding(GO:0043199)
0.1 0.6 GO:0034603 pyruvate dehydrogenase activity(GO:0004738) pyruvate dehydrogenase [NAD(P)+] activity(GO:0034603) pyruvate dehydrogenase (NAD+) activity(GO:0034604)
0.1 0.9 GO:0052656 branched-chain-amino-acid transaminase activity(GO:0004084) L-leucine transaminase activity(GO:0052654) L-valine transaminase activity(GO:0052655) L-isoleucine transaminase activity(GO:0052656)
0.1 0.9 GO:0015087 cobalt ion transmembrane transporter activity(GO:0015087)
0.1 1.6 GO:0008484 sulfuric ester hydrolase activity(GO:0008484)
0.1 0.3 GO:0001565 phorbol ester receptor activity(GO:0001565) non-kinase phorbol ester receptor activity(GO:0001566)
0.1 5.0 GO:0004177 aminopeptidase activity(GO:0004177)
0.1 1.1 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.1 0.3 GO:0016316 phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316) phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity(GO:0034597)
0.1 0.7 GO:0008310 single-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008310)
0.1 2.1 GO:1900750 glutathione binding(GO:0043295) oligopeptide binding(GO:1900750)
0.1 0.6 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.1 0.6 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.1 1.6 GO:0005537 mannose binding(GO:0005537)
0.1 0.6 GO:0003910 DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910)
0.1 0.4 GO:0004647 phosphoserine phosphatase activity(GO:0004647)
0.1 0.5 GO:0005519 cytoskeletal regulatory protein binding(GO:0005519)
0.0 0.8 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.0 0.1 GO:0005174 CD40 receptor binding(GO:0005174)
0.0 1.2 GO:0016891 endoribonuclease activity, producing 5'-phosphomonoesters(GO:0016891)
0.0 0.2 GO:0005134 interleukin-2 receptor binding(GO:0005134)
0.0 0.3 GO:0001849 complement component C1q binding(GO:0001849)
0.0 0.8 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.0 0.2 GO:0015616 DNA translocase activity(GO:0015616)
0.0 0.4 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.0 0.8 GO:0005337 nucleoside transmembrane transporter activity(GO:0005337)
0.0 1.1 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.0 1.1 GO:0031435 mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.0 2.1 GO:0050840 extracellular matrix binding(GO:0050840)
0.0 1.7 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
0.0 1.2 GO:0003785 actin monomer binding(GO:0003785)
0.0 0.9 GO:0004623 phospholipase A2 activity(GO:0004623)
0.0 0.2 GO:0008479 queuine tRNA-ribosyltransferase activity(GO:0008479)
0.0 0.7 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.0 0.4 GO:0042166 acetylcholine binding(GO:0042166)
0.0 0.3 GO:0070181 small ribosomal subunit rRNA binding(GO:0070181)
0.0 0.2 GO:0005004 GPI-linked ephrin receptor activity(GO:0005004)
0.0 0.5 GO:0004993 G-protein coupled serotonin receptor activity(GO:0004993)
0.0 0.8 GO:0008536 Ran GTPase binding(GO:0008536)
0.0 0.2 GO:0004908 interleukin-1 receptor activity(GO:0004908)
0.0 0.4 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0 0.0 GO:0047936 glucose 1-dehydrogenase [NAD(P)] activity(GO:0047936)
0.0 0.3 GO:0005132 type I interferon receptor binding(GO:0005132)
0.0 0.6 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.0 0.1 GO:0045134 uridine-diphosphatase activity(GO:0045134)
0.0 0.6 GO:0005109 frizzled binding(GO:0005109)
0.0 0.3 GO:0050811 GABA receptor binding(GO:0050811)
0.0 2.2 GO:0005125 cytokine activity(GO:0005125)
0.0 1.6 GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor(GO:0016616)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 8.0 PID FGF PATHWAY FGF signaling pathway
0.1 7.7 PID IL4 2PATHWAY IL4-mediated signaling events
0.1 1.4 PID IL27 PATHWAY IL27-mediated signaling events
0.0 1.7 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.0 2.3 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 1.6 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.0 2.3 SIG PIP3 SIGNALING IN CARDIAC MYOCTES Genes related to PIP3 signaling in cardiac myocytes
0.0 0.6 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining
0.0 1.9 PID AP1 PATHWAY AP-1 transcription factor network
0.0 1.1 PID CD8 TCR DOWNSTREAM PATHWAY Downstream signaling in naïve CD8+ T cells
0.0 0.6 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.0 0.5 ST DIFFERENTIATION PATHWAY IN PC12 CELLS Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.
0.0 2.0 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.0 0.4 PID ERBB2 ERBB3 PATHWAY ErbB2/ErbB3 signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 8.0 REACTOME FGFR4 LIGAND BINDING AND ACTIVATION Genes involved in FGFR4 ligand binding and activation
0.2 2.9 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.2 4.5 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 7ALPHA HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol
0.2 1.6 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.1 4.8 REACTOME STEROID HORMONES Genes involved in Steroid hormones
0.1 3.3 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.1 2.7 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.1 0.6 REACTOME HORMONE LIGAND BINDING RECEPTORS Genes involved in Hormone ligand-binding receptors
0.1 0.9 REACTOME ACYL CHAIN REMODELLING OF PS Genes involved in Acyl chain remodelling of PS
0.1 1.4 REACTOME RNA POL III TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase III Transcription Termination
0.0 0.6 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0 2.2 REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION Genes involved in Transport to the Golgi and subsequent modification
0.0 2.1 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.0 0.6 REACTOME INTEGRATION OF PROVIRUS Genes involved in Integration of provirus
0.0 0.9 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.0 2.6 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.0 1.7 REACTOME IL RECEPTOR SHC SIGNALING Genes involved in Interleukin receptor SHC signaling
0.0 0.9 REACTOME COMPLEMENT CASCADE Genes involved in Complement cascade
0.0 0.4 REACTOME IRAK1 RECRUITS IKK COMPLEX Genes involved in IRAK1 recruits IKK complex
0.0 0.4 REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.0 0.6 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.0 1.1 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.0 0.8 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 0.7 REACTOME AMINE LIGAND BINDING RECEPTORS Genes involved in Amine ligand-binding receptors
0.0 0.3 REACTOME REGULATION OF IFNA SIGNALING Genes involved in Regulation of IFNA signaling
0.0 0.8 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.0 0.3 REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
0.0 0.5 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)