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GSE58827: Dynamics of the Mouse Liver

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Results for Esrrb_Esrra

Z-value: 1.11

Motif logo

Transcription factors associated with Esrrb_Esrra

Gene Symbol Gene ID Gene Info
ENSMUSG00000021255.18 estrogen related receptor, beta
ENSMUSG00000024955.16 estrogen related receptor, alpha

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Esrramm39_v1_chr19_-_6899173_68992080.676.4e-06Click!
Esrrbmm39_v1_chr12_+_86516875_86516897-0.317.0e-02Click!

Activity profile of Esrrb_Esrra motif

Sorted Z-values of Esrrb_Esrra motif

Promoter Log-likelihood Transcript Gene Gene Info
chr19_-_43512929 18.30 ENSMUST00000026196.14
glutamic-oxaloacetic transaminase 1, soluble
chr15_+_76579885 11.93 ENSMUST00000231028.2
glutamic pyruvic transaminase, soluble
chr17_-_35077089 10.57 ENSMUST00000153400.8
complement factor B
chr15_+_76579960 10.35 ENSMUST00000229679.2
glutamic pyruvic transaminase, soluble
chr2_+_102536701 9.42 ENSMUST00000123759.8
ENSMUST00000005220.11
ENSMUST00000111212.8
solute carrier family 1 (glial high affinity glutamate transporter), member 2
chr4_-_107164347 8.66 ENSMUST00000082426.11
deiodinase, iodothyronine, type I
chr4_-_107164315 8.24 ENSMUST00000126291.2
ENSMUST00000106748.2
ENSMUST00000129138.2
deiodinase, iodothyronine, type I
chr10_+_128030315 7.90 ENSMUST00000044776.13
glutaminase 2 (liver, mitochondrial)
chr6_+_90527762 6.70 ENSMUST00000130418.8
ENSMUST00000032175.11
ENSMUST00000203111.2
aldehyde dehydrogenase 1 family, member L1
chr18_+_45402018 6.39 ENSMUST00000183850.8
ENSMUST00000066890.14
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 2
chr10_+_128030500 6.28 ENSMUST00000123291.2
glutaminase 2 (liver, mitochondrial)
chr4_+_134123631 6.08 ENSMUST00000105869.9
platelet-activating factor acetylhydrolase 2
chr7_-_105249308 5.59 ENSMUST00000210531.2
ENSMUST00000033185.10
hemopexin
chr9_-_46146558 5.20 ENSMUST00000121916.8
ENSMUST00000034586.9
apolipoprotein C-III
chr9_-_46146928 4.69 ENSMUST00000118649.8
apolipoprotein C-III
chr15_+_25843225 4.62 ENSMUST00000022881.15
reticulophagy regulator 1
chr15_+_7159038 4.19 ENSMUST00000067190.12
ENSMUST00000164529.9
LIF receptor alpha
chr4_+_140688514 3.98 ENSMUST00000010007.9
succinate dehydrogenase complex, subunit B, iron sulfur (Ip)
chr17_-_32639936 3.95 ENSMUST00000170392.9
ENSMUST00000237165.2
ENSMUST00000235892.2
ENSMUST00000114455.3
peptidoglycan recognition protein 2
chr10_-_71180763 3.92 ENSMUST00000045887.9
CDGSH iron sulfur domain 1
chr15_+_76227695 3.92 ENSMUST00000023210.8
ENSMUST00000231045.2
cytochrome c-1
chr5_-_123320767 3.87 ENSMUST00000154713.8
ENSMUST00000031398.14
4-hydroxyphenylpyruvic acid dioxygenase
chr9_-_107546166 3.81 ENSMUST00000177567.8
solute carrier family 38, member 3
chr13_-_74498320 3.78 ENSMUST00000221594.2
ENSMUST00000022062.8
succinate dehydrogenase complex, subunit A, flavoprotein (Fp)
chr9_-_107546195 3.73 ENSMUST00000192990.6
solute carrier family 38, member 3
chr7_-_140856642 3.68 ENSMUST00000080654.7
ENSMUST00000167263.9
cadherin-related family member 5
chr7_+_26821266 3.52 ENSMUST00000206552.2
cytochrome P450, family 2, subfamily f, polypeptide 2
chr3_+_32791139 3.48 ENSMUST00000127477.8
ENSMUST00000121778.8
ENSMUST00000154257.8
NADH:ubiquinone oxidoreductase subunit B5
chr2_-_25391729 3.47 ENSMUST00000015227.4
complement component 8, gamma polypeptide
chr19_-_3962733 3.46 ENSMUST00000075092.8
ENSMUST00000235847.2
ENSMUST00000235301.2
ENSMUST00000237341.2
NADH:ubiquinone oxidoreductase core subunit S8
chr11_+_98932062 3.43 ENSMUST00000017637.13
insulin-like growth factor binding protein 4
chr8_-_13544478 3.35 ENSMUST00000033828.7
growth arrest specific 6
chr15_+_3300249 3.33 ENSMUST00000082424.12
ENSMUST00000159158.9
ENSMUST00000159216.10
ENSMUST00000160311.3
selenoprotein P
chr5_-_147259245 3.31 ENSMUST00000100433.5
ureidoimidazoline (2-oxo-4-hydroxy-4-carboxy-5) decarboxylase
chr18_-_10706701 3.29 ENSMUST00000002549.9
ENSMUST00000117726.9
ENSMUST00000117828.9
abhydrolase domain containing 3
chr9_-_106125055 3.22 ENSMUST00000074082.13
aminolevulinic acid synthase 1
chr5_+_114284585 3.22 ENSMUST00000102582.8
acetyl-Coenzyme A carboxylase beta
chr7_-_81356653 3.09 ENSMUST00000026922.15
homer scaffolding protein 2
chr13_+_84370405 3.06 ENSMUST00000057495.10
ENSMUST00000225069.2
transmembrane protein 161B
chr9_-_70048766 3.05 ENSMUST00000034749.16
family with sequence similarity 81, member A
chr9_+_107957621 3.05 ENSMUST00000035211.14
macrophage stimulating 1 (hepatocyte growth factor-like)
chr7_-_81356557 3.03 ENSMUST00000207983.2
homer scaffolding protein 2
chr1_-_175453117 3.02 ENSMUST00000027810.14
fumarate hydratase 1
chr11_-_53321606 3.00 ENSMUST00000061326.5
ENSMUST00000109021.4
ubiquinol-cytochrome c reductase, complex III subunit VII
chr9_+_107957640 3.00 ENSMUST00000162886.2
macrophage stimulating 1 (hepatocyte growth factor-like)
chr6_-_113508536 2.95 ENSMUST00000032425.7
ER membrane protein complex subunit 3
chr15_-_96947963 2.93 ENSMUST00000230907.2
solute carrier family 38, member 4
chr8_+_95564949 2.90 ENSMUST00000034234.15
ENSMUST00000159871.4
coenzyme Q9
chr11_-_11848107 2.86 ENSMUST00000178704.8
dopa decarboxylase
chr6_+_125297596 2.86 ENSMUST00000176655.8
ENSMUST00000176110.8
sodium channel, nonvoltage-gated 1 alpha
chr4_+_155646807 2.84 ENSMUST00000030939.14
NAD kinase
chr11_-_11848044 2.82 ENSMUST00000066237.10
dopa decarboxylase
chr2_-_157408239 2.82 ENSMUST00000109528.9
ENSMUST00000088494.3
bladder cancer associated protein
chr2_+_103396638 2.80 ENSMUST00000076212.4
ankyrin repeat and BTB (POZ) domain containing 2
chr7_-_48494959 2.79 ENSMUST00000208050.2
cysteine and glycine-rich protein 3
chr13_-_86194889 2.78 ENSMUST00000131011.2
cytochrome c oxidase subunit 7C
chr2_+_155359868 2.76 ENSMUST00000029135.15
ENSMUST00000065973.9
acyl-CoA synthetase short-chain family member 2
chr9_+_55234197 2.74 ENSMUST00000085754.10
ENSMUST00000034862.5
transmembrane protein 266
chr17_-_56424265 2.74 ENSMUST00000113072.3
perilipin 5
chr3_-_90421557 2.72 ENSMUST00000107340.2
ENSMUST00000060738.9
S100 calcium binding protein A1
chr14_-_20844074 2.71 ENSMUST00000080440.14
ENSMUST00000100837.11
ENSMUST00000071816.7
calcium/calmodulin-dependent protein kinase II gamma
chr6_+_145156860 2.66 ENSMUST00000111725.8
ENSMUST00000111726.10
ENSMUST00000039729.5
ENSMUST00000111723.8
ENSMUST00000111724.8
ENSMUST00000111721.2
ENSMUST00000111719.2
electron transfer flavoprotein regulatory factor 1
chr4_+_62278932 2.66 ENSMUST00000084526.12
solute carrier family 31, member 1
chr11_-_94568228 2.64 ENSMUST00000116349.9
xylosyltransferase II
chr7_-_30755007 2.64 ENSMUST00000206474.2
ENSMUST00000205807.2
ENSMUST00000039909.13
ENSMUST00000206305.2
ENSMUST00000205439.2
FXYD domain-containing ion transport regulator 1
chr17_-_56424577 2.60 ENSMUST00000019808.12
perilipin 5
chr18_+_9212154 2.55 ENSMUST00000041080.7
frizzled class receptor 8
chr11_-_118139331 2.53 ENSMUST00000017276.14
cytohesin 1
chr10_+_79552421 2.48 ENSMUST00000099513.8
ENSMUST00000020581.3
hyperpolarization-activated, cyclic nucleotide-gated K+ 2
chr11_+_120375439 2.43 ENSMUST00000043627.8
mitochondrial ribosomal protein L12
chrX_-_51254129 2.38 ENSMUST00000033450.3
glypican 4
chr4_-_129121676 2.38 ENSMUST00000106051.8
expressed sequence C77080
chr7_-_126944578 2.37 ENSMUST00000060783.7
zinc finger protein 768
chr19_-_6957789 2.33 ENSMUST00000070878.9
ENSMUST00000177752.9
FK506 binding protein 2
chr17_+_44263890 2.33 ENSMUST00000177857.9
ENSMUST00000044792.6
regulator of calcineurin 2
chr1_+_72863641 2.31 ENSMUST00000047328.11
insulin-like growth factor binding protein 2
chr17_-_26087696 2.30 ENSMUST00000236479.2
ENSMUST00000235806.2
ENSMUST00000026828.7
MAPK regulated corepressor interacting protein 2
chr4_+_128887017 2.28 ENSMUST00000030583.13
ENSMUST00000102604.11
adenylate kinase 2
chr16_-_37474772 2.27 ENSMUST00000023514.4
NADH:ubiquinone oxidoreductase subunit B4
chr8_+_121395047 2.27 ENSMUST00000181795.2
cytochrome c oxidase subunit 4I1
chrX_-_47602395 2.26 ENSMUST00000114945.9
ENSMUST00000037349.8
apoptosis-inducing factor, mitochondrion-associated 1
chr9_-_121686601 2.26 ENSMUST00000213124.2
ENSMUST00000215300.2
ENSMUST00000213147.2
HIG1 domain family, member 1A
chr11_+_74540284 2.25 ENSMUST00000117818.2
ENSMUST00000092915.12
clustered mitochondria (cluA/CLU1) homolog
chr3_+_90421742 2.23 ENSMUST00000048138.8
S100 calcium binding protein A13
chr14_-_20844034 2.22 ENSMUST00000226630.2
calcium/calmodulin-dependent protein kinase II gamma
chr9_-_121686643 2.20 ENSMUST00000215007.2
ENSMUST00000216914.2
HIG1 domain family, member 1A
chr7_+_83281167 2.17 ENSMUST00000075418.15
StAR-related lipid transfer (START) domain containing 5
chr9_+_65536892 2.14 ENSMUST00000169003.8
RNA binding protein with multiple splicing 2
chr7_-_126944754 2.09 ENSMUST00000205266.2
zinc finger protein 768
chr4_-_19708910 2.09 ENSMUST00000108246.9
WW domain containing E3 ubiquitin protein ligase 1
chr3_-_131096792 2.08 ENSMUST00000200236.2
ENSMUST00000106337.7
cytochrome P450, family 2, subfamily u, polypeptide 1
chr8_-_71315902 2.07 ENSMUST00000212611.2
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 1
chr18_+_77861656 2.05 ENSMUST00000114748.2
ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1
chr16_+_22769822 2.04 ENSMUST00000023590.9
histidine-rich glycoprotein
chr13_-_53083494 2.03 ENSMUST00000123599.8
AU RNA binding protein/enoyl-coenzyme A hydratase
chr13_+_51254852 1.98 ENSMUST00000095797.6
spindlin 1
chr13_-_67053384 1.98 ENSMUST00000021993.5
ubiquinol-cytochrome c reductase binding protein
chr19_+_4761181 1.97 ENSMUST00000008991.8
spectrin beta, non-erythrocytic 2
chr15_+_10224052 1.95 ENSMUST00000128450.8
ENSMUST00000148257.8
ENSMUST00000128921.8
prolactin receptor
chr2_-_84508385 1.93 ENSMUST00000189772.2
ENSMUST00000053664.9
ENSMUST00000111664.8
predicted gene 28635
thioredoxin-related transmembrane protein 2
chr11_+_115353290 1.93 ENSMUST00000106532.4
ENSMUST00000092445.12
ENSMUST00000153466.2
solute carrier family 16 (monocarboxylic acid transporters), member 5
chr9_+_107217786 1.92 ENSMUST00000042581.4
RIKEN cDNA 6430571L13 gene
chr4_-_6275629 1.90 ENSMUST00000029905.2
cytochrome P450, family 7, subfamily a, polypeptide 1
chr2_-_73741664 1.90 ENSMUST00000111996.8
ENSMUST00000018914.3
ATP synthase, H+ transporting, mitochondrial F0 complex, subunit C3 (subunit 9)
chr1_+_4878046 1.89 ENSMUST00000027036.11
ENSMUST00000150971.8
ENSMUST00000119612.9
ENSMUST00000137887.8
ENSMUST00000115529.8
lysophospholipase 1
chr1_+_74324089 1.88 ENSMUST00000113805.8
ENSMUST00000027370.13
ENSMUST00000087226.11
paroxysmal nonkinesiogenic dyskinesia
chr11_+_75084609 1.88 ENSMUST00000102514.4
reticulon 4 receptor-like 1
chr16_+_22769844 1.88 ENSMUST00000232422.2
histidine-rich glycoprotein
chr10_-_78300802 1.86 ENSMUST00000041616.15
pyridoxal (pyridoxine, vitamin B6) kinase
chr8_-_125296435 1.86 ENSMUST00000238882.2
ENSMUST00000063278.7
angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
chr8_-_70975734 1.82 ENSMUST00000137610.3
KxDL motif containing 1
chr9_-_21913833 1.80 ENSMUST00000115336.10
outer dynein arm docking complex subunit 3
chr16_+_10363203 1.78 ENSMUST00000115824.10
C-type lectin domain family 16, member A
chr1_-_175319842 1.78 ENSMUST00000195324.6
ENSMUST00000192227.6
ENSMUST00000194555.6
regulator of G protein signaling 7
chr16_+_10363222 1.77 ENSMUST00000155633.8
ENSMUST00000066345.15
C-type lectin domain family 16, member A
chr9_-_44714263 1.77 ENSMUST00000044694.8
tetratricopeptide repeat domain 36
chr9_+_65538352 1.75 ENSMUST00000216342.2
ENSMUST00000216382.2
RNA binding protein with multiple splicing 2
chr11_-_118139312 1.74 ENSMUST00000100181.11
cytohesin 1
chr11_-_118139418 1.72 ENSMUST00000106305.9
cytohesin 1
chr6_+_71176811 1.71 ENSMUST00000067492.8
fatty acid binding protein 1, liver
chr5_-_87572060 1.71 ENSMUST00000072818.6
UDP glucuronosyltransferase 2 family, polypeptide B38
chr9_-_50515089 1.70 ENSMUST00000000175.6
succinate dehydrogenase complex, subunit D, integral membrane protein
chr18_+_77273510 1.70 ENSMUST00000075290.8
ENSMUST00000079618.11
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 5
chr14_+_79086665 1.69 ENSMUST00000227255.2
von Willebrand factor A domain containing 8
chr4_-_148244028 1.69 ENSMUST00000167160.8
ENSMUST00000151246.8
F-box protein 44
chr7_+_119217004 1.69 ENSMUST00000047929.13
ENSMUST00000135683.3
acyl-CoA synthetase medium-chain family member 1
chr16_+_10363254 1.65 ENSMUST00000115827.8
ENSMUST00000150894.2
ENSMUST00000038145.13
C-type lectin domain family 16, member A
chr3_+_96484294 1.65 ENSMUST00000148290.2
predicted gene 16253
chr9_-_21913896 1.65 ENSMUST00000044926.6
outer dynein arm docking complex subunit 3
chr11_+_75400889 1.65 ENSMUST00000042972.7
Rab interacting lysosomal protein
chr9_-_63306497 1.64 ENSMUST00000168665.3
RIKEN cDNA 2300009A05 gene
chrX_-_71699740 1.61 ENSMUST00000055966.13
gamma-aminobutyric acid (GABA) A receptor, subunit alpha 3
chr4_-_8239034 1.61 ENSMUST00000066674.8
carbonic anhydrase 8
chr19_-_34856853 1.61 ENSMUST00000036584.13
pantothenate kinase 1
chr4_+_138161958 1.61 ENSMUST00000044058.11
ENSMUST00000105813.8
ENSMUST00000105815.2
mitochondrial ubiquitin ligase activator of NFKB 1
chr15_+_68800261 1.60 ENSMUST00000022954.7
KH domain containing, RNA binding, signal transduction associated 3
chr16_+_22926162 1.60 ENSMUST00000023599.13
ENSMUST00000168891.8
eukaryotic translation initiation factor 4A2
chr16_+_22926504 1.60 ENSMUST00000187168.7
ENSMUST00000232287.2
ENSMUST00000077605.12
eukaryotic translation initiation factor 4A2
chr15_-_76191301 1.59 ENSMUST00000171340.9
ENSMUST00000023222.13
ENSMUST00000164189.2
5-oxoprolinase (ATP-hydrolysing)
chr7_-_4525793 1.59 ENSMUST00000140424.8
troponin I, cardiac 3
chr11_-_116089595 1.59 ENSMUST00000072948.11
acyl-Coenzyme A oxidase 1, palmitoyl
chr4_-_122854966 1.59 ENSMUST00000030408.12
ENSMUST00000127047.2
major facilitator superfamily domain containing 2A
chr6_+_91134358 1.57 ENSMUST00000155007.2
histone deacetylase 11
chr4_+_140970161 1.56 ENSMUST00000138096.8
ENSMUST00000006618.9
ENSMUST00000125392.8
Rho guanine nucleotide exchange factor (GEF) 19
chr19_-_47079052 1.56 ENSMUST00000235771.2
ENSMUST00000096014.5
ENSMUST00000236170.2
ATP synthase membrane subunit DAPIT
chr11_+_98239230 1.56 ENSMUST00000078694.13
protein phosphatase 1, regulatory inhibitor subunit 1B
chr16_-_23339548 1.54 ENSMUST00000089883.7
mannan-binding lectin serine peptidase 1
chr2_-_102903680 1.54 ENSMUST00000132449.8
ENSMUST00000111183.2
ENSMUST00000011058.9
pyruvate dehydrogenase complex, component X
chr7_-_80053063 1.53 ENSMUST00000147150.2
furin (paired basic amino acid cleaving enzyme)
chr6_+_91133647 1.53 ENSMUST00000041736.11
histone deacetylase 11
chr11_-_72157419 1.51 ENSMUST00000208056.2
ENSMUST00000208912.2
ENSMUST00000140167.3
ENSMUST00000137701.3
solute carrier family 13 (sodium-dependent citrate transporter), member 5
chr11_-_116089866 1.51 ENSMUST00000066587.12
acyl-Coenzyme A oxidase 1, palmitoyl
chr11_-_96720309 1.51 ENSMUST00000167149.8
nuclear factor, erythroid derived 2,-like 1
chr4_-_49408040 1.50 ENSMUST00000081541.9
acyl-coenzyme A amino acid N-acyltransferase 2
chr14_+_79086492 1.48 ENSMUST00000040990.7
von Willebrand factor A domain containing 8
chr8_+_121394961 1.47 ENSMUST00000034276.13
ENSMUST00000181586.8
cytochrome c oxidase subunit 4I1
chr6_+_91133755 1.47 ENSMUST00000143621.8
histone deacetylase 11
chr19_+_3372296 1.44 ENSMUST00000237938.2
carnitine palmitoyltransferase 1a, liver
chr4_-_83242490 1.41 ENSMUST00000102823.10
tetratricopeptide repeat domain 39B
chr2_+_166647426 1.41 ENSMUST00000099078.10
ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited)
chr12_-_71183371 1.39 ENSMUST00000221367.2
ENSMUST00000220482.2
ENSMUST00000221892.2
ENSMUST00000221178.2
ENSMUST00000221559.2
ENSMUST00000166120.9
ENSMUST00000021486.10
ENSMUST00000221797.2
ENSMUST00000221815.2
translocase of inner mitochondrial membrane 9
chr9_-_106562852 1.38 ENSMUST00000169068.8
testis expressed gene 264
chr15_-_83989801 1.37 ENSMUST00000229826.2
ENSMUST00000082365.6
sulfotransferase family 4A, member 1
chr7_+_127399776 1.36 ENSMUST00000046863.12
ENSMUST00000206674.2
ENSMUST00000106272.8
hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7
chr9_-_106124917 1.35 ENSMUST00000112524.9
ENSMUST00000219129.2
aminolevulinic acid synthase 1
chr7_+_29883611 1.33 ENSMUST00000208441.2
cytochrome c oxidase subunit 7A1
chr5_-_23881353 1.32 ENSMUST00000198661.5
serine/arginine-rich protein specific kinase 2
chr11_-_60702081 1.32 ENSMUST00000018744.15
serine hydroxymethyltransferase 1 (soluble)
chr19_-_7194912 1.32 ENSMUST00000039758.6
cytochrome c oxidase subunit 8A
chr15_+_100659729 1.29 ENSMUST00000161564.2
solute carrier family 4 (anion exchanger), member 8
chr15_-_77813123 1.29 ENSMUST00000109748.9
ENSMUST00000109747.9
ENSMUST00000100486.6
ENSMUST00000005487.12
thioredoxin 2
chr11_-_59118988 1.29 ENSMUST00000163300.8
ENSMUST00000061242.8
ADP-ribosylation factor 1
chr2_-_10084866 1.29 ENSMUST00000130067.2
ENSMUST00000139810.8
ATP synthase, H+ transporting, mitochondrial F1 complex, gamma polypeptide 1
chr6_+_39569502 1.28 ENSMUST00000135671.8
ENSMUST00000119379.2
NADH:ubiquinone oxidoreductase subunit B2
chr11_+_120382666 1.28 ENSMUST00000026899.4
solute carrier family 25 (mitochondrial carrier, dicarboxylate transporter), member 10
chr10_+_127919142 1.27 ENSMUST00000026459.6
ATP synthase, H+ transporting mitochondrial F1 complex, beta subunit
chr5_-_25200745 1.27 ENSMUST00000076306.12
protein kinase, AMP-activated, gamma 2 non-catalytic subunit
chr2_-_160169414 1.26 ENSMUST00000099127.3
predicted gene 826
chr7_+_127399789 1.26 ENSMUST00000125188.8
hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7
chr1_-_134163102 1.26 ENSMUST00000187631.2
ENSMUST00000038191.8
ENSMUST00000086465.6
adenosine A1 receptor
chr13_-_25121568 1.25 ENSMUST00000037615.7
aldhehyde dehydrogenase family 5, subfamily A1
chr2_+_140012560 1.24 ENSMUST00000044825.5
NADH:ubiquinone oxidoreductase complex assembly factor 5
chr5_+_150042092 1.24 ENSMUST00000200960.4
ENSMUST00000202530.4
FRY microtubule binding protein
chr1_+_153300874 1.24 ENSMUST00000042373.12
Shc SH2-domain binding protein 1-like
chr8_-_110305672 1.24 ENSMUST00000074898.8
haptoglobin
chr15_+_74435587 1.23 ENSMUST00000185682.7
ENSMUST00000170845.8
ENSMUST00000187599.2
adhesion G protein-coupled receptor B1
chr11_-_72157450 1.22 ENSMUST00000021161.14
solute carrier family 13 (sodium-dependent citrate transporter), member 5
chr10_-_42354276 1.21 ENSMUST00000151747.8
AFG1 like ATPase
chr4_-_40279382 1.21 ENSMUST00000108108.3
ENSMUST00000095128.10
NADH:ubiquinone oxidoreductase subunit B6
chr7_-_96981221 1.21 ENSMUST00000139582.9
ubiquitin specific peptidase 35
chr7_-_119122681 1.20 ENSMUST00000033267.4
protein disulfide isomerase-like, testis expressed
chr7_-_16761790 1.19 ENSMUST00000003183.12
protein phosphatase 5, catalytic subunit
chr9_-_110709175 1.18 ENSMUST00000050958.9
transmembrane inner ear
chr4_+_150321659 1.18 ENSMUST00000133839.8
enolase 1, alpha non-neuron
chr5_+_30437579 1.17 ENSMUST00000145167.9
selenoprotein I
chr11_+_70735572 1.17 ENSMUST00000076270.13
ENSMUST00000179114.8
ENSMUST00000100928.11
rabaptin, RAB GTPase binding effector protein 1
chr4_+_150321272 1.17 ENSMUST00000080926.13
enolase 1, alpha non-neuron
chr18_-_79152504 1.16 ENSMUST00000025430.11
SET binding protein 1
chr4_-_131871797 1.16 ENSMUST00000056336.2
opioid receptor, delta 1
chr9_-_21996693 1.16 ENSMUST00000179422.8
ENSMUST00000098937.10
ENSMUST00000177967.2
ENSMUST00000180180.8
ECSIT signalling integrator

Network of associatons between targets according to the STRING database.

First level regulatory network of Esrrb_Esrra

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
7.1 21.3 GO:0006106 fumarate metabolic process(GO:0006106)
2.5 7.5 GO:2000487 asparagine transport(GO:0006867) positive regulation of glutamine transport(GO:2000487)
2.5 9.9 GO:0010982 regulation of high-density lipoprotein particle clearance(GO:0010982)
2.2 6.7 GO:0009397 10-formyltetrahydrofolate catabolic process(GO:0009258) folic acid-containing compound catabolic process(GO:0009397) pteridine-containing compound catabolic process(GO:0042560)
2.1 12.4 GO:0006543 glutamine catabolic process(GO:0006543)
1.7 5.2 GO:1904766 negative regulation of macroautophagy by TORC1 signaling(GO:1904766)
1.4 9.5 GO:0015886 heme transport(GO:0015886)
1.3 9.4 GO:0070777 D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
1.3 3.8 GO:2001293 fatty-acyl-CoA biosynthetic process(GO:0046949) malonyl-CoA metabolic process(GO:2001293)
1.2 3.5 GO:0090420 naphthalene metabolic process(GO:0018931) naphthalene-containing compound metabolic process(GO:0090420)
1.1 5.5 GO:0006121 mitochondrial electron transport, succinate to ubiquinone(GO:0006121)
1.1 6.5 GO:0042776 mitochondrial ATP synthesis coupled proton transport(GO:0042776)
1.1 5.3 GO:0010897 negative regulation of triglyceride catabolic process(GO:0010897) negative regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035359)
1.0 4.0 GO:0015744 succinate transport(GO:0015744)
0.9 2.8 GO:1903920 positive regulation of actin filament severing(GO:1903920)
0.9 2.8 GO:0019542 acetate biosynthetic process(GO:0019413) acetyl-CoA biosynthetic process from acetate(GO:0019427) propionate biosynthetic process(GO:0019542)
0.8 3.3 GO:0019064 fusion of virus membrane with host plasma membrane(GO:0019064) membrane fusion involved in viral entry into host cell(GO:0039663) multi-organism membrane fusion(GO:0044800)
0.8 14.0 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.8 5.7 GO:0015842 aminergic neurotransmitter loading into synaptic vesicle(GO:0015842)
0.8 4.0 GO:0006105 succinate metabolic process(GO:0006105)
0.7 10.8 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.7 3.4 GO:1904970 brush border assembly(GO:1904970)
0.7 6.0 GO:0060763 mammary duct terminal end bud growth(GO:0060763)
0.7 1.3 GO:0021941 negative regulation of cerebellar granule cell precursor proliferation(GO:0021941)
0.7 2.6 GO:0030210 heparin biosynthetic process(GO:0030210)
0.7 4.0 GO:0000270 peptidoglycan metabolic process(GO:0000270) peptidoglycan catabolic process(GO:0009253) negative regulation of natural killer cell differentiation(GO:0032824) negative regulation of natural killer cell differentiation involved in immune response(GO:0032827)
0.6 3.7 GO:0001980 regulation of systemic arterial blood pressure by ischemic conditions(GO:0001980)
0.6 1.9 GO:0042822 pyridoxal phosphate metabolic process(GO:0042822)
0.6 1.9 GO:0061461 regulation of extracellular matrix constituent secretion(GO:0003330) positive regulation of extracellular matrix constituent secretion(GO:0003331) lysine import(GO:0034226) L-lysine import(GO:0061461) L-lysine import into cell(GO:1903410)
0.6 3.6 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
0.6 4.2 GO:0048861 leukemia inhibitory factor signaling pathway(GO:0048861)
0.6 1.8 GO:0097212 lysosomal membrane organization(GO:0097212)
0.6 6.4 GO:0098914 membrane repolarization during atrial cardiac muscle cell action potential(GO:0098914)
0.6 5.7 GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
0.5 3.3 GO:0006172 ADP biosynthetic process(GO:0006172)
0.5 1.6 GO:0051977 lysophospholipid transport(GO:0051977)
0.5 3.1 GO:0033540 fatty acid beta-oxidation using acyl-CoA oxidase(GO:0033540)
0.5 4.4 GO:0061709 reticulophagy(GO:0061709)
0.5 1.8 GO:0060785 regulation of apoptosis involved in tissue homeostasis(GO:0060785)
0.4 1.3 GO:0070676 intralumenal vesicle formation(GO:0070676)
0.4 1.3 GO:0019264 glycine biosynthetic process from serine(GO:0019264)
0.4 0.9 GO:1904457 positive regulation of neuronal action potential(GO:1904457)
0.4 3.9 GO:0006572 tyrosine catabolic process(GO:0006572)
0.4 1.3 GO:0070256 positive regulation of nucleobase-containing compound transport(GO:0032241) regulation of nucleoside transport(GO:0032242) negative regulation of circadian sleep/wake cycle, non-REM sleep(GO:0042323) negative regulation of mucus secretion(GO:0070256)
0.4 1.3 GO:0006538 glutamate catabolic process(GO:0006538)
0.4 3.3 GO:0001887 selenium compound metabolic process(GO:0001887)
0.4 1.2 GO:0030961 peptidyl-arginine hydroxylation(GO:0030961)
0.4 1.2 GO:2000295 regulation of hydrogen peroxide catabolic process(GO:2000295)
0.4 1.2 GO:0046901 tetrahydrofolylpolyglutamate biosynthetic process(GO:0046901)
0.4 1.5 GO:0090472 dibasic protein processing(GO:0090472)
0.4 1.9 GO:0070859 positive regulation of bile acid biosynthetic process(GO:0070859) positive regulation of bile acid metabolic process(GO:1904253)
0.4 2.7 GO:0072719 cellular response to cisplatin(GO:0072719) copper ion import across plasma membrane(GO:0098705) copper ion import into cell(GO:1902861)
0.4 2.3 GO:0098734 protein depalmitoylation(GO:0002084) macromolecule depalmitoylation(GO:0098734)
0.4 17.5 GO:0032981 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.4 0.7 GO:0034197 acylglycerol transport(GO:0034196) triglyceride transport(GO:0034197)
0.4 2.5 GO:0071321 cellular response to cGMP(GO:0071321) potassium ion import across plasma membrane(GO:1990573)
0.3 2.0 GO:0038161 prolactin signaling pathway(GO:0038161)
0.3 3.6 GO:1903278 positive regulation of sodium ion export(GO:1903275) positive regulation of sodium ion export from cell(GO:1903278)
0.3 9.0 GO:0015985 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.3 3.5 GO:0000255 allantoin metabolic process(GO:0000255)
0.3 1.0 GO:0046108 uridine catabolic process(GO:0006218) uridine metabolic process(GO:0046108)
0.3 2.8 GO:0006741 NADP biosynthetic process(GO:0006741)
0.3 1.6 GO:0007621 negative regulation of female receptivity(GO:0007621)
0.3 1.2 GO:1904428 negative regulation of tubulin deacetylation(GO:1904428)
0.3 1.2 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
0.3 2.1 GO:0034551 respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551)
0.3 1.4 GO:0035063 nuclear speck organization(GO:0035063)
0.3 1.4 GO:0034371 chylomicron remodeling(GO:0034371)
0.3 0.8 GO:0035606 peptidyl-cysteine S-trans-nitrosylation(GO:0035606)
0.3 1.1 GO:1903070 negative regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903070)
0.3 1.6 GO:1901526 negative regulation of defense response to virus by host(GO:0050689) regulation of chemokine (C-C motif) ligand 5 production(GO:0071649) positive regulation of macromitophagy(GO:1901526) positive regulation of mitophagy in response to mitochondrial depolarization(GO:1904925)
0.3 2.6 GO:0035754 B cell chemotaxis(GO:0035754)
0.3 1.0 GO:1902037 negative regulation of hematopoietic stem cell differentiation(GO:1902037)
0.3 6.1 GO:0048875 chemical homeostasis within a tissue(GO:0048875)
0.3 0.8 GO:0071579 regulation of zinc ion transport(GO:0071579)
0.2 2.2 GO:0050703 interleukin-1 alpha secretion(GO:0050703)
0.2 0.7 GO:2000275 regulation of oxidative phosphorylation uncoupler activity(GO:2000275)
0.2 0.7 GO:0060450 hindgut contraction(GO:0043133) regulation of hindgut contraction(GO:0043134) positive regulation of hindgut contraction(GO:0060450)
0.2 3.2 GO:0032000 positive regulation of fatty acid beta-oxidation(GO:0032000)
0.2 1.9 GO:0061732 mitochondrial acetyl-CoA biosynthetic process from pyruvate(GO:0061732)
0.2 1.0 GO:0086046 membrane depolarization during SA node cell action potential(GO:0086046)
0.2 2.4 GO:0061727 methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione(GO:0019243) methylglyoxal catabolic process(GO:0051596) methylglyoxal catabolic process to lactate(GO:0061727)
0.2 3.6 GO:0051151 negative regulation of smooth muscle cell differentiation(GO:0051151)
0.2 0.9 GO:2000795 negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
0.2 3.1 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.2 0.9 GO:0050823 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent(GO:0002479) peptide stabilization(GO:0050822) peptide antigen stabilization(GO:0050823)
0.2 0.7 GO:1901856 negative regulation of cellular respiration(GO:1901856)
0.2 0.7 GO:0042694 muscle cell fate specification(GO:0042694)
0.2 3.0 GO:0006390 transcription from mitochondrial promoter(GO:0006390)
0.2 0.9 GO:0010747 positive regulation of plasma membrane long-chain fatty acid transport(GO:0010747)
0.2 0.9 GO:0055014 atrial cardiac muscle cell differentiation(GO:0055011) atrial cardiac muscle cell development(GO:0055014)
0.2 5.5 GO:0006783 heme biosynthetic process(GO:0006783)
0.2 1.0 GO:0010636 positive regulation of mitochondrial fusion(GO:0010636)
0.2 0.8 GO:0050747 positive regulation of lipoprotein metabolic process(GO:0050747)
0.2 7.2 GO:0032012 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.2 2.3 GO:0043567 regulation of insulin-like growth factor receptor signaling pathway(GO:0043567)
0.2 2.9 GO:0035376 sterol import(GO:0035376) cholesterol import(GO:0070508)
0.2 0.6 GO:0060060 post-embryonic retina morphogenesis in camera-type eye(GO:0060060)
0.2 2.9 GO:0031581 hemidesmosome assembly(GO:0031581)
0.2 0.4 GO:0032730 regulation of interleukin-1 alpha production(GO:0032650) positive regulation of interleukin-1 alpha production(GO:0032730)
0.2 1.8 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
0.2 0.5 GO:0070681 glutaminyl-tRNAGln biosynthesis via transamidation(GO:0070681)
0.2 0.7 GO:1902269 positive regulation of polyamine transmembrane transport(GO:1902269)
0.2 17.3 GO:0042446 hormone biosynthetic process(GO:0042446)
0.2 1.4 GO:0007597 blood coagulation, intrinsic pathway(GO:0007597)
0.2 2.5 GO:0016576 histone dephosphorylation(GO:0016576)
0.2 3.0 GO:0043568 positive regulation of insulin-like growth factor receptor signaling pathway(GO:0043568)
0.2 1.2 GO:0038003 opioid receptor signaling pathway(GO:0038003)
0.2 0.7 GO:0000105 histidine biosynthetic process(GO:0000105)
0.2 2.1 GO:0016554 cytidine to uridine editing(GO:0016554)
0.2 0.8 GO:0072363 regulation of glycolytic process by positive regulation of transcription from RNA polymerase II promoter(GO:0072363)
0.2 0.5 GO:0019626 short-chain fatty acid catabolic process(GO:0019626)
0.2 0.9 GO:0016557 peroxisome membrane biogenesis(GO:0016557)
0.2 0.8 GO:1902809 regulation of skeletal muscle fiber differentiation(GO:1902809)
0.2 0.6 GO:0035524 proline transmembrane transport(GO:0035524)
0.2 0.5 GO:0045013 carbon catabolite repression of transcription(GO:0045013) negative regulation of transcription by glucose(GO:0045014)
0.1 0.3 GO:0090598 male genitalia morphogenesis(GO:0048808) male anatomical structure morphogenesis(GO:0090598)
0.1 0.7 GO:0045964 negative regulation of serotonin secretion(GO:0014063) positive regulation of catecholamine metabolic process(GO:0045915) positive regulation of dopamine metabolic process(GO:0045964)
0.1 0.4 GO:0046166 alditol catabolic process(GO:0019405) glyceraldehyde-3-phosphate biosynthetic process(GO:0046166)
0.1 1.8 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.1 0.4 GO:0036079 GDP-fucose transport(GO:0015783) purine nucleotide-sugar transport(GO:0036079)
0.1 0.9 GO:0006499 N-terminal protein myristoylation(GO:0006499)
0.1 1.8 GO:0070166 enamel mineralization(GO:0070166)
0.1 0.9 GO:0090074 negative regulation of protein homodimerization activity(GO:0090074)
0.1 0.5 GO:0036367 adaptation of rhodopsin mediated signaling(GO:0016062) light adaption(GO:0036367)
0.1 3.2 GO:1901897 regulation of relaxation of cardiac muscle(GO:1901897)
0.1 1.9 GO:1901387 positive regulation of voltage-gated calcium channel activity(GO:1901387)
0.1 0.4 GO:0048162 preantral ovarian follicle growth(GO:0001546) multi-layer follicle stage(GO:0048162)
0.1 0.6 GO:0006627 protein processing involved in protein targeting to mitochondrion(GO:0006627)
0.1 0.4 GO:0009188 ribonucleoside diphosphate biosynthetic process(GO:0009188)
0.1 4.1 GO:0022904 respiratory electron transport chain(GO:0022904)
0.1 1.6 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
0.1 0.4 GO:0046337 phosphatidylethanolamine metabolic process(GO:0046337)
0.1 1.0 GO:0006102 isocitrate metabolic process(GO:0006102)
0.1 0.7 GO:0098532 histone H3-K27 trimethylation(GO:0098532)
0.1 2.0 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
0.1 2.7 GO:0090201 negative regulation of release of cytochrome c from mitochondria(GO:0090201)
0.1 0.7 GO:0030043 actin filament fragmentation(GO:0030043)
0.1 2.7 GO:0043457 regulation of cellular respiration(GO:0043457)
0.1 0.5 GO:0002905 mature B cell apoptotic process(GO:0002901) regulation of mature B cell apoptotic process(GO:0002905) negative regulation of mature B cell apoptotic process(GO:0002906)
0.1 3.0 GO:0007614 short-term memory(GO:0007614)
0.1 0.6 GO:0098886 modification of dendritic spine(GO:0098886)
0.1 0.7 GO:0015824 proline transport(GO:0015824)
0.1 1.8 GO:0048312 intracellular distribution of mitochondria(GO:0048312)
0.1 2.0 GO:0009083 branched-chain amino acid catabolic process(GO:0009083)
0.1 3.3 GO:0046470 phosphatidylcholine metabolic process(GO:0046470)
0.1 0.4 GO:0098964 dendritic transport of ribonucleoprotein complex(GO:0098961) dendritic transport of messenger ribonucleoprotein complex(GO:0098963) anterograde dendritic transport of messenger ribonucleoprotein complex(GO:0098964)
0.1 1.9 GO:0048681 negative regulation of axon regeneration(GO:0048681)
0.1 0.5 GO:0070346 positive regulation of fat cell proliferation(GO:0070346)
0.1 2.0 GO:0042759 long-chain fatty acid biosynthetic process(GO:0042759)
0.1 0.3 GO:2000813 negative regulation of barbed-end actin filament capping(GO:2000813)
0.1 1.7 GO:0015693 magnesium ion transport(GO:0015693)
0.1 0.3 GO:0021852 pyramidal neuron migration(GO:0021852)
0.1 0.9 GO:0006642 triglyceride mobilization(GO:0006642)
0.1 1.1 GO:0097421 liver regeneration(GO:0097421)
0.1 2.8 GO:0097237 cellular response to toxic substance(GO:0097237)
0.1 1.0 GO:0051665 membrane raft localization(GO:0051665)
0.1 2.2 GO:0036295 cellular response to increased oxygen levels(GO:0036295) response to increased oxygen levels(GO:0036296)
0.1 0.9 GO:0032485 regulation of Ral protein signal transduction(GO:0032485)
0.1 0.5 GO:0060336 negative regulation of response to interferon-gamma(GO:0060331) negative regulation of interferon-gamma-mediated signaling pathway(GO:0060336)
0.1 2.7 GO:0006491 N-glycan processing(GO:0006491)
0.1 0.5 GO:0060455 negative regulation of gastric acid secretion(GO:0060455)
0.1 0.3 GO:0021558 trochlear nerve development(GO:0021558)
0.1 4.6 GO:0014003 oligodendrocyte development(GO:0014003)
0.1 0.6 GO:0051013 microtubule severing(GO:0051013)
0.1 0.1 GO:0001698 gastrin-induced gastric acid secretion(GO:0001698)
0.1 4.5 GO:0050909 sensory perception of taste(GO:0050909)
0.1 0.4 GO:0007207 adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197) phospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway(GO:0007207)
0.1 0.9 GO:0051204 protein insertion into mitochondrial membrane(GO:0051204)
0.1 0.7 GO:0015722 canalicular bile acid transport(GO:0015722)
0.1 0.4 GO:1900454 positive regulation of long term synaptic depression(GO:1900454)
0.1 2.8 GO:0030262 apoptotic nuclear changes(GO:0030262)
0.1 0.6 GO:0090234 regulation of kinetochore assembly(GO:0090234)
0.1 0.5 GO:1903300 negative regulation of glucokinase activity(GO:0033132) negative regulation of hexokinase activity(GO:1903300)
0.1 0.4 GO:0046341 CDP-diacylglycerol metabolic process(GO:0046341)
0.1 0.1 GO:0009608 response to symbiont(GO:0009608) response to symbiotic bacterium(GO:0009609)
0.1 1.0 GO:0006654 phosphatidic acid biosynthetic process(GO:0006654)
0.1 0.6 GO:0035902 response to immobilization stress(GO:0035902)
0.1 0.3 GO:0044208 'de novo' AMP biosynthetic process(GO:0044208)
0.1 0.6 GO:0036444 calcium ion transmembrane import into mitochondrion(GO:0036444)
0.1 0.3 GO:0035973 aggrephagy(GO:0035973)
0.1 0.2 GO:0033577 protein glycosylation in endoplasmic reticulum(GO:0033577)
0.1 0.3 GO:0017187 peptidyl-glutamic acid carboxylation(GO:0017187)
0.1 0.3 GO:0003050 regulation of systemic arterial blood pressure by atrial natriuretic peptide(GO:0003050)
0.1 1.4 GO:0016226 iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
0.1 1.0 GO:0031937 positive regulation of chromatin silencing(GO:0031937)
0.1 0.2 GO:0060112 positive regulation of luteinizing hormone secretion(GO:0033686) generation of ovulation cycle rhythm(GO:0060112)
0.1 0.5 GO:0016056 rhodopsin mediated signaling pathway(GO:0016056)
0.1 2.9 GO:0003333 amino acid transmembrane transport(GO:0003333)
0.1 0.9 GO:0007007 inner mitochondrial membrane organization(GO:0007007) cristae formation(GO:0042407)
0.1 1.3 GO:0006662 glycerol ether metabolic process(GO:0006662)
0.1 0.3 GO:0042908 xenobiotic transport(GO:0042908)
0.1 0.3 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)
0.1 0.9 GO:0006388 tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
0.1 0.3 GO:0009298 GDP-mannose biosynthetic process(GO:0009298)
0.1 2.0 GO:0009303 rRNA transcription(GO:0009303)
0.1 0.3 GO:0048550 negative regulation of pinocytosis(GO:0048550)
0.1 0.1 GO:0014734 skeletal muscle hypertrophy(GO:0014734)
0.1 0.4 GO:0070070 proton-transporting V-type ATPase complex assembly(GO:0070070) vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
0.1 0.5 GO:0044539 long-chain fatty acid import(GO:0044539)
0.1 0.2 GO:0033239 negative regulation of cellular amine metabolic process(GO:0033239) negative regulation of cellular amino acid metabolic process(GO:0045763)
0.1 0.2 GO:2000397 regulation of ubiquitin-dependent endocytosis(GO:2000395) positive regulation of ubiquitin-dependent endocytosis(GO:2000397)
0.1 0.7 GO:0070255 regulation of mucus secretion(GO:0070255)
0.1 2.5 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.1 0.8 GO:0061525 hindgut development(GO:0061525)
0.1 0.3 GO:0099566 regulation of postsynaptic cytosolic calcium ion concentration(GO:0099566)
0.1 2.1 GO:0006110 regulation of glycolytic process(GO:0006110)
0.1 1.3 GO:0021692 cerebellar Purkinje cell layer morphogenesis(GO:0021692)
0.1 0.6 GO:0045348 positive regulation of MHC class II biosynthetic process(GO:0045348)
0.1 0.2 GO:0035609 C-terminal protein deglutamylation(GO:0035609)
0.1 0.6 GO:0070345 negative regulation of fat cell proliferation(GO:0070345)
0.1 0.9 GO:0006614 SRP-dependent cotranslational protein targeting to membrane(GO:0006614)
0.1 0.4 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.1 1.2 GO:0050910 detection of mechanical stimulus involved in sensory perception of sound(GO:0050910)
0.1 1.0 GO:0061179 negative regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061179)
0.1 0.5 GO:0030007 cellular potassium ion homeostasis(GO:0030007)
0.1 0.6 GO:1904294 positive regulation of ERAD pathway(GO:1904294)
0.0 0.7 GO:0071670 smooth muscle cell chemotaxis(GO:0071670)
0.0 0.5 GO:0051045 negative regulation of membrane protein ectodomain proteolysis(GO:0051045)
0.0 0.5 GO:0042637 catagen(GO:0042637)
0.0 0.4 GO:0006689 ganglioside catabolic process(GO:0006689)
0.0 1.3 GO:0008206 bile acid metabolic process(GO:0008206)
0.0 0.1 GO:1904349 positive regulation of response to food(GO:0032097) positive regulation of appetite(GO:0032100) negative regulation of circadian sleep/wake cycle, REM sleep(GO:0042322) positive regulation of eating behavior(GO:1904000) regulation of gastric mucosal blood circulation(GO:1904344) positive regulation of gastric mucosal blood circulation(GO:1904346) regulation of small intestine smooth muscle contraction(GO:1904347) positive regulation of small intestine smooth muscle contraction(GO:1904349) gastric mucosal blood circulation(GO:1990768) small intestine smooth muscle contraction(GO:1990770) negative regulation of energy homeostasis(GO:2000506)
0.0 0.9 GO:1900017 positive regulation of cytokine production involved in inflammatory response(GO:1900017)
0.0 0.8 GO:0051560 mitochondrial calcium ion homeostasis(GO:0051560)
0.0 0.7 GO:0006308 DNA catabolic process(GO:0006308)
0.0 0.2 GO:2000973 regulation of pro-B cell differentiation(GO:2000973)
0.0 1.1 GO:0046688 response to copper ion(GO:0046688)
0.0 1.3 GO:0019432 triglyceride biosynthetic process(GO:0019432)
0.0 0.4 GO:0097151 positive regulation of inhibitory postsynaptic potential(GO:0097151)
0.0 0.9 GO:0050908 detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962)
0.0 1.8 GO:0006805 xenobiotic metabolic process(GO:0006805)
0.0 0.1 GO:0070973 protein localization to endoplasmic reticulum exit site(GO:0070973)
0.0 0.7 GO:0000338 protein deneddylation(GO:0000338)
0.0 2.6 GO:0035383 acyl-CoA metabolic process(GO:0006637) thioester metabolic process(GO:0035383)
0.0 0.2 GO:1905150 regulation of voltage-gated sodium channel activity(GO:1905150)
0.0 0.6 GO:2001014 regulation of skeletal muscle cell differentiation(GO:2001014)
0.0 0.8 GO:0003334 keratinocyte development(GO:0003334)
0.0 0.1 GO:0033058 directional locomotion(GO:0033058)
0.0 0.2 GO:0032929 negative regulation of superoxide anion generation(GO:0032929)
0.0 0.1 GO:0048936 peripheral nervous system neuron axonogenesis(GO:0048936)
0.0 0.2 GO:1902163 negative regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902163)
0.0 1.4 GO:0061049 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.0 0.5 GO:0035814 negative regulation of renal sodium excretion(GO:0035814)
0.0 0.9 GO:0043153 photoperiodism(GO:0009648) entrainment of circadian clock by photoperiod(GO:0043153)
0.0 2.2 GO:0006749 glutathione metabolic process(GO:0006749)
0.0 2.7 GO:0051965 positive regulation of synapse assembly(GO:0051965)
0.0 0.3 GO:0035269 protein O-linked mannosylation(GO:0035269)
0.0 0.2 GO:0036353 histone H2A-K119 monoubiquitination(GO:0036353)
0.0 0.5 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.0 0.4 GO:0030238 male sex determination(GO:0030238)
0.0 0.5 GO:0044065 regulation of respiratory system process(GO:0044065)
0.0 1.0 GO:0051443 positive regulation of ubiquitin-protein transferase activity(GO:0051443)
0.0 2.5 GO:0060997 dendritic spine morphogenesis(GO:0060997)
0.0 1.4 GO:0010501 RNA secondary structure unwinding(GO:0010501)
0.0 2.2 GO:0061077 chaperone-mediated protein folding(GO:0061077)
0.0 0.1 GO:0072014 proximal tubule development(GO:0072014) regulation of androgen receptor activity(GO:2000823)
0.0 0.3 GO:0000012 single strand break repair(GO:0000012)
0.0 0.3 GO:0055098 response to low-density lipoprotein particle(GO:0055098)
0.0 0.6 GO:0032674 regulation of interleukin-5 production(GO:0032674)
0.0 0.9 GO:0000266 mitochondrial fission(GO:0000266)
0.0 0.6 GO:0032506 cytokinetic process(GO:0032506)
0.0 0.1 GO:1900248 cytoplasmic translational elongation(GO:0002182) regulation of cytoplasmic translational elongation(GO:1900247) negative regulation of cytoplasmic translational elongation(GO:1900248) positive regulation of mRNA polyadenylation(GO:1900365)
0.0 0.4 GO:1902175 regulation of oxidative stress-induced intrinsic apoptotic signaling pathway(GO:1902175)
0.0 0.5 GO:1902230 negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902230)
0.0 0.3 GO:0010650 positive regulation of cell communication by electrical coupling(GO:0010650) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.0 0.2 GO:0070102 interleukin-6-mediated signaling pathway(GO:0070102)
0.0 0.1 GO:0036394 amylase secretion(GO:0036394)
0.0 0.6 GO:0045187 regulation of circadian sleep/wake cycle, sleep(GO:0045187)
0.0 0.3 GO:0060732 positive regulation of inositol phosphate biosynthetic process(GO:0060732)
0.0 1.9 GO:0043507 positive regulation of JUN kinase activity(GO:0043507)
0.0 0.4 GO:0045161 neuronal ion channel clustering(GO:0045161)
0.0 1.8 GO:0002088 lens development in camera-type eye(GO:0002088)
0.0 0.3 GO:0007095 mitotic G2 DNA damage checkpoint(GO:0007095)
0.0 0.1 GO:0090400 stress-induced premature senescence(GO:0090400)
0.0 0.8 GO:0048488 synaptic vesicle endocytosis(GO:0048488)
0.0 1.1 GO:0009062 fatty acid catabolic process(GO:0009062)
0.0 0.1 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.0 0.1 GO:0005981 regulation of glycogen catabolic process(GO:0005981)
0.0 0.3 GO:2000060 positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:2000060)
0.0 0.2 GO:0035021 negative regulation of Rac protein signal transduction(GO:0035021)
0.0 1.2 GO:0030816 positive regulation of cAMP metabolic process(GO:0030816)
0.0 1.0 GO:0046928 regulation of neurotransmitter secretion(GO:0046928)
0.0 0.7 GO:0042771 intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:0042771)
0.0 0.7 GO:0006829 zinc II ion transport(GO:0006829)
0.0 0.5 GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.0 0.4 GO:0045823 positive regulation of heart contraction(GO:0045823)
0.0 0.3 GO:0008272 sulfate transport(GO:0008272)
0.0 0.3 GO:0060065 uterus development(GO:0060065)
0.0 0.2 GO:1903818 positive regulation of voltage-gated potassium channel activity(GO:1903818)
0.0 0.0 GO:0000960 mitochondrial RNA catabolic process(GO:0000957) regulation of mitochondrial RNA catabolic process(GO:0000960)
0.0 0.2 GO:2000311 regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000311)
0.0 0.2 GO:0048199 vesicle targeting, to, from or within Golgi(GO:0048199)
0.0 0.6 GO:0048701 embryonic cranial skeleton morphogenesis(GO:0048701)
0.0 0.3 GO:0031572 G2 DNA damage checkpoint(GO:0031572)
0.0 0.6 GO:1900087 positive regulation of G1/S transition of mitotic cell cycle(GO:1900087)
0.0 0.1 GO:0032780 negative regulation of ATPase activity(GO:0032780)
0.0 0.2 GO:0002029 desensitization of G-protein coupled receptor protein signaling pathway(GO:0002029) negative adaptation of signaling pathway(GO:0022401)
0.0 0.1 GO:0071231 neural crest cell migration involved in heart formation(GO:0003147) anterior neural tube closure(GO:0061713) cellular response to folic acid(GO:0071231)
0.0 0.4 GO:0048240 sperm capacitation(GO:0048240)
0.0 0.1 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.0 0.7 GO:0001676 long-chain fatty acid metabolic process(GO:0001676)
0.0 0.1 GO:0018094 protein polyglycylation(GO:0018094)
0.0 0.8 GO:0031398 positive regulation of protein ubiquitination(GO:0031398)
0.0 0.2 GO:0035641 locomotory exploration behavior(GO:0035641)
0.0 0.3 GO:0010569 regulation of double-strand break repair via homologous recombination(GO:0010569)
0.0 0.3 GO:0035066 positive regulation of histone acetylation(GO:0035066)
0.0 0.1 GO:0035845 photoreceptor cell outer segment organization(GO:0035845)
0.0 0.1 GO:1902259 regulation of delayed rectifier potassium channel activity(GO:1902259)
0.0 0.1 GO:0035507 regulation of myosin-light-chain-phosphatase activity(GO:0035507)
0.0 0.6 GO:2000134 negative regulation of G1/S transition of mitotic cell cycle(GO:2000134)
0.0 0.1 GO:0002827 positive regulation of T-helper 1 type immune response(GO:0002827)
0.0 1.1 GO:0042472 inner ear morphogenesis(GO:0042472)
0.0 0.2 GO:1903543 regulation of exosomal secretion(GO:1903541) positive regulation of exosomal secretion(GO:1903543)
0.0 0.2 GO:0034063 stress granule assembly(GO:0034063)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
2.4 9.5 GO:0045281 mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283)
1.7 5.2 GO:0036020 endolysosome membrane(GO:0036020)
1.3 3.9 GO:0061474 phagolysosome membrane(GO:0061474)
0.9 10.3 GO:0005750 mitochondrial respiratory chain complex III(GO:0005750)
0.9 9.9 GO:0034363 intermediate-density lipoprotein particle(GO:0034363)
0.8 2.5 GO:0098855 HCN channel complex(GO:0098855)
0.6 2.5 GO:1990851 Wnt-Frizzled-LRP5/6 complex(GO:1990851)
0.6 9.8 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.6 5.1 GO:0045261 mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275) proton-transporting ATP synthase complex, catalytic core F(1)(GO:0045261)
0.5 2.7 GO:0017177 glucosidase II complex(GO:0017177)
0.4 1.2 GO:0042721 mitochondrial inner membrane protein insertion complex(GO:0042721)
0.4 3.5 GO:0005579 membrane attack complex(GO:0005579)
0.4 2.3 GO:0097226 sperm mitochondrial sheath(GO:0097226)
0.4 2.6 GO:1990584 cardiac Troponin complex(GO:1990584)
0.4 3.7 GO:0089717 spanning component of plasma membrane(GO:0044214) spanning component of membrane(GO:0089717)
0.4 1.4 GO:0032280 axonemal microtubule(GO:0005879) symmetric synapse(GO:0032280)
0.3 5.4 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.3 4.4 GO:0072546 ER membrane protein complex(GO:0072546)
0.3 22.4 GO:0070469 respiratory chain(GO:0070469)
0.3 1.9 GO:0045254 pyruvate dehydrogenase complex(GO:0045254)
0.2 1.2 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.2 2.0 GO:0008091 spectrin(GO:0008091)
0.2 3.3 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.2 1.2 GO:0031314 extrinsic component of mitochondrial inner membrane(GO:0031314)
0.2 2.2 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.2 0.7 GO:0005757 mitochondrial permeability transition pore complex(GO:0005757)
0.2 0.5 GO:0032437 cuticular plate(GO:0032437)
0.2 0.5 GO:0030956 glutamyl-tRNA(Gln) amidotransferase complex(GO:0030956)
0.2 0.9 GO:0044316 cone cell pedicle(GO:0044316)
0.2 1.9 GO:0072669 tRNA-splicing ligase complex(GO:0072669)
0.2 0.7 GO:0046691 intracellular canaliculus(GO:0046691)
0.2 1.9 GO:0045179 apical cortex(GO:0045179)
0.2 2.3 GO:1990635 proximal dendrite(GO:1990635)
0.2 0.7 GO:0097598 sperm cytoplasmic droplet(GO:0097598)
0.2 4.5 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.2 2.6 GO:0098799 outer mitochondrial membrane protein complex(GO:0098799)
0.2 8.5 GO:0030673 axolemma(GO:0030673)
0.2 3.8 GO:0032426 stereocilium tip(GO:0032426)
0.1 6.8 GO:0005790 smooth endoplasmic reticulum(GO:0005790)
0.1 0.4 GO:0043291 RAVE complex(GO:0043291)
0.1 0.6 GO:0097444 spine apparatus(GO:0097444)
0.1 0.7 GO:0098560 cytoplasmic side of late endosome membrane(GO:0098560)
0.1 0.8 GO:0097452 GAIT complex(GO:0097452)
0.1 0.9 GO:0042824 MHC class I peptide loading complex(GO:0042824) TAP complex(GO:0042825)
0.1 0.3 GO:0071914 prominosome(GO:0071914)
0.1 4.0 GO:0034706 sodium channel complex(GO:0034706)
0.1 0.9 GO:0005785 signal recognition particle receptor complex(GO:0005785)
0.1 1.2 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.1 0.9 GO:0061617 MICOS complex(GO:0061617)
0.1 1.2 GO:0072687 meiotic spindle(GO:0072687)
0.1 11.9 GO:0016528 sarcoplasm(GO:0016528)
0.1 0.3 GO:0070069 cytochrome complex(GO:0070069)
0.1 1.1 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.1 1.0 GO:0001520 outer dense fiber(GO:0001520)
0.1 0.4 GO:0045251 mitochondrial electron transfer flavoprotein complex(GO:0017133) electron transfer flavoprotein complex(GO:0045251)
0.1 1.5 GO:0012510 trans-Golgi network transport vesicle membrane(GO:0012510)
0.1 1.8 GO:0005782 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.1 1.4 GO:0045239 tricarboxylic acid cycle enzyme complex(GO:0045239)
0.1 5.6 GO:0005801 cis-Golgi network(GO:0005801)
0.1 22.9 GO:0005759 mitochondrial matrix(GO:0005759)
0.1 1.4 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.1 1.4 GO:0044292 dendrite terminus(GO:0044292)
0.1 18.6 GO:0043679 axon terminus(GO:0043679)
0.1 6.2 GO:0005778 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.1 0.1 GO:0097418 neurofibrillary tangle(GO:0097418)
0.1 0.4 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.1 0.6 GO:0005766 primary lysosome(GO:0005766) azurophil granule(GO:0042582)
0.1 0.5 GO:0031983 vesicle lumen(GO:0031983)
0.1 1.3 GO:1902711 GABA-A receptor complex(GO:1902711)
0.1 5.3 GO:0005811 lipid particle(GO:0005811)
0.1 6.6 GO:0042579 peroxisome(GO:0005777) microbody(GO:0042579)
0.1 0.6 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.0 0.9 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.0 15.8 GO:0005743 mitochondrial inner membrane(GO:0005743)
0.0 3.9 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.0 2.2 GO:0034707 chloride channel complex(GO:0034707)
0.0 0.1 GO:0032156 septin cytoskeleton(GO:0032156)
0.0 3.7 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 0.4 GO:0031595 nuclear proteasome complex(GO:0031595)
0.0 0.6 GO:0042788 polysomal ribosome(GO:0042788)
0.0 1.4 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.0 0.1 GO:0043540 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex(GO:0043540)
0.0 1.3 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.0 0.5 GO:0042613 MHC class II protein complex(GO:0042613)
0.0 0.3 GO:0044354 pinosome(GO:0044352) macropinosome(GO:0044354)
0.0 0.7 GO:0061702 inflammasome complex(GO:0061702)
0.0 0.3 GO:0097648 G-protein coupled receptor dimeric complex(GO:0038037) G-protein coupled receptor complex(GO:0097648)
0.0 2.0 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 1.0 GO:0045095 keratin filament(GO:0045095)
0.0 0.1 GO:0098984 asymmetric synapse(GO:0032279) neuron to neuron synapse(GO:0098984)
0.0 0.5 GO:0031083 BLOC-1 complex(GO:0031083)
0.0 0.7 GO:0031528 microvillus membrane(GO:0031528)
0.0 0.4 GO:0060077 inhibitory synapse(GO:0060077)
0.0 0.5 GO:0030914 STAGA complex(GO:0030914)
0.0 4.5 GO:0008021 synaptic vesicle(GO:0008021)
0.0 5.0 GO:0031234 extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.0 0.3 GO:0032593 insulin-responsive compartment(GO:0032593)
0.0 2.9 GO:0000118 histone deacetylase complex(GO:0000118)
0.0 5.2 GO:0005770 late endosome(GO:0005770)
0.0 0.6 GO:0032809 neuronal cell body membrane(GO:0032809)
0.0 2.6 GO:0030139 endocytic vesicle(GO:0030139)
0.0 0.3 GO:0008385 IkappaB kinase complex(GO:0008385)
0.0 0.1 GO:0005863 striated muscle myosin thick filament(GO:0005863)
0.0 0.6 GO:0034451 centriolar satellite(GO:0034451)
0.0 0.4 GO:0002080 acrosomal membrane(GO:0002080)
0.0 0.1 GO:1990923 PET complex(GO:1990923)
0.0 0.7 GO:0008180 COP9 signalosome(GO:0008180)
0.0 2.2 GO:0031966 mitochondrial membrane(GO:0031966)
0.0 0.2 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.0 0.7 GO:0001750 photoreceptor outer segment(GO:0001750)
0.0 17.7 GO:0005783 endoplasmic reticulum(GO:0005783)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
6.1 18.3 GO:0080130 L-phenylalanine:2-oxoglutarate aminotransferase activity(GO:0080130)
4.5 22.3 GO:0004021 L-alanine:2-oxoglutarate aminotransferase activity(GO:0004021) alanine-oxo-acid transaminase activity(GO:0047635)
4.2 16.9 GO:0004800 thyroxine 5'-deiodinase activity(GO:0004800)
3.2 9.5 GO:0008177 succinate dehydrogenase (ubiquinone) activity(GO:0008177)
2.5 9.9 GO:0070653 high-density lipoprotein particle receptor binding(GO:0070653)
2.2 6.7 GO:0016155 formyltetrahydrofolate dehydrogenase activity(GO:0016155)
2.1 12.4 GO:0004359 glutaminase activity(GO:0004359)
1.9 7.5 GO:0015182 L-asparagine transmembrane transporter activity(GO:0015182)
1.6 9.4 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
1.5 4.6 GO:0016749 5-aminolevulinate synthase activity(GO:0003870) N-succinyltransferase activity(GO:0016749)
1.4 5.7 GO:0036468 aromatic-L-amino-acid decarboxylase activity(GO:0004058) L-dopa decarboxylase activity(GO:0036468)
1.3 3.9 GO:0008127 4-hydroxyphenylpyruvate dioxygenase activity(GO:0003868) quercetin 2,3-dioxygenase activity(GO:0008127)
1.0 4.0 GO:0015141 succinate transmembrane transporter activity(GO:0015141)
0.9 8.5 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.9 5.6 GO:0015232 heme transporter activity(GO:0015232)
0.9 2.6 GO:0030158 protein xylosyltransferase activity(GO:0030158)
0.9 6.1 GO:0030160 GKAP/Homer scaffold activity(GO:0030160)
0.8 4.2 GO:0004923 leukemia inhibitory factor receptor activity(GO:0004923)
0.8 3.3 GO:0043532 angiostatin binding(GO:0043532)
0.8 4.7 GO:0008970 phosphatidylcholine 1-acylhydrolase activity(GO:0008970)
0.8 3.8 GO:0003989 acetyl-CoA carboxylase activity(GO:0003989)
0.7 4.0 GO:0016019 N-acetylmuramoyl-L-alanine amidase activity(GO:0008745) peptidoglycan receptor activity(GO:0016019)
0.7 2.6 GO:0047016 cholest-5-ene-3-beta,7-alpha-diol 3-beta-dehydrogenase activity(GO:0047016)
0.6 5.2 GO:0008121 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.6 1.9 GO:0070279 vitamin B6 binding(GO:0070279)
0.6 1.7 GO:0016213 linoleoyl-CoA desaturase activity(GO:0016213)
0.6 5.7 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.6 3.9 GO:0016401 palmitoyl-CoA oxidase activity(GO:0016401)
0.6 2.8 GO:0003987 acetate-CoA ligase activity(GO:0003987)
0.5 2.6 GO:0004174 electron-transferring-flavoprotein dehydrogenase activity(GO:0004174) oxidoreductase activity, acting on the CH-NH group of donors, quinone or similar compound as acceptor(GO:0016649)
0.5 1.6 GO:0031751 D4 dopamine receptor binding(GO:0031751)
0.5 1.4 GO:1990698 palmitoleoyltransferase activity(GO:1990698)
0.5 0.9 GO:0051538 3 iron, 4 sulfur cluster binding(GO:0051538)
0.5 1.8 GO:0072541 peroxynitrite reductase activity(GO:0072541)
0.5 13.3 GO:0015002 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.4 1.3 GO:0004372 glycine hydroxymethyltransferase activity(GO:0004372)
0.4 6.1 GO:0003847 1-alkyl-2-acetylglycerophosphocholine esterase activity(GO:0003847)
0.4 4.6 GO:0032052 bile acid binding(GO:0032052)
0.4 2.5 GO:0005222 intracellular cAMP activated cation channel activity(GO:0005222)
0.4 5.3 GO:0035473 lipase binding(GO:0035473)
0.4 2.8 GO:0061629 RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629)
0.4 2.0 GO:0004925 prolactin receptor activity(GO:0004925)
0.4 1.2 GO:0004326 tetrahydrofolylpolyglutamate synthase activity(GO:0004326)
0.4 1.9 GO:0034603 pyruvate dehydrogenase activity(GO:0004738) pyruvate dehydrogenase [NAD(P)+] activity(GO:0034603) pyruvate dehydrogenase (NAD+) activity(GO:0034604)
0.4 2.6 GO:0030172 troponin C binding(GO:0030172)
0.4 6.2 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.3 1.0 GO:0031755 endothelial differentiation G-protein coupled receptor binding(GO:0031753) Edg-2 lysophosphatidic acid receptor binding(GO:0031755)
0.3 1.3 GO:0008113 peptide-methionine (S)-S-oxide reductase activity(GO:0008113)
0.3 3.6 GO:0015280 ligand-gated sodium channel activity(GO:0015280)
0.3 2.4 GO:0004416 hydroxyacylglutathione hydrolase activity(GO:0004416)
0.3 1.2 GO:0004307 ethanolaminephosphotransferase activity(GO:0004307)
0.3 1.8 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.3 1.6 GO:0004594 pantothenate kinase activity(GO:0004594)
0.3 2.3 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.2 3.4 GO:0004017 adenylate kinase activity(GO:0004017)
0.2 3.3 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.2 2.3 GO:0098599 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.2 2.2 GO:0050786 RAGE receptor binding(GO:0050786)
0.2 1.1 GO:1904288 BAT3 complex binding(GO:1904288)
0.2 1.3 GO:0008607 phosphorylase kinase regulator activity(GO:0008607)
0.2 1.7 GO:0003996 acyl-CoA ligase activity(GO:0003996)
0.2 2.1 GO:0015288 porin activity(GO:0015288)
0.2 0.8 GO:0019828 aspartic-type endopeptidase inhibitor activity(GO:0019828)
0.2 6.2 GO:0008137 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.2 1.2 GO:0004985 opioid receptor activity(GO:0004985)
0.2 3.5 GO:0019841 retinol binding(GO:0019841)
0.2 1.9 GO:0035374 chondroitin sulfate binding(GO:0035374)
0.2 0.4 GO:0004127 cytidylate kinase activity(GO:0004127)
0.2 0.6 GO:0086059 voltage-gated calcium channel activity involved SA node cell action potential(GO:0086059)
0.2 0.7 GO:0061628 H3K27me3 modified histone binding(GO:0061628)
0.2 2.7 GO:0005375 copper ion transmembrane transporter activity(GO:0005375)
0.2 0.5 GO:0050567 glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity(GO:0050567)
0.2 1.6 GO:0016812 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides(GO:0016812)
0.2 1.2 GO:0030492 hemoglobin binding(GO:0030492)
0.2 1.1 GO:0004784 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.2 0.7 GO:0042978 ornithine decarboxylase activator activity(GO:0042978)
0.2 1.9 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.2 0.5 GO:0030337 DNA polymerase processivity factor activity(GO:0030337)
0.2 3.8 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.2 3.9 GO:0009055 electron carrier activity(GO:0009055)
0.2 2.0 GO:0004300 enoyl-CoA hydratase activity(GO:0004300)
0.2 7.2 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.2 3.5 GO:0019825 oxygen binding(GO:0019825)
0.2 0.6 GO:0004104 choline kinase activity(GO:0004103) cholinesterase activity(GO:0004104)
0.2 1.0 GO:0004850 uridine phosphorylase activity(GO:0004850)
0.2 1.0 GO:0070004 cysteine-type carboxypeptidase activity(GO:0016807) cysteine-type exopeptidase activity(GO:0070004)
0.2 0.8 GO:0070012 oligopeptidase activity(GO:0070012)
0.2 0.9 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.2 3.5 GO:0030296 protein tyrosine kinase activator activity(GO:0030296)
0.1 0.9 GO:0005047 signal recognition particle binding(GO:0005047)
0.1 1.0 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.1 2.7 GO:0044548 S100 protein binding(GO:0044548)
0.1 1.3 GO:0032795 heterotrimeric G-protein binding(GO:0032795)
0.1 4.0 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.1 0.4 GO:0036080 GDP-fucose transmembrane transporter activity(GO:0005457) purine nucleotide-sugar transmembrane transporter activity(GO:0036080)
0.1 0.4 GO:0086062 voltage-gated sodium channel activity involved in Purkinje myocyte action potential(GO:0086062)
0.1 0.4 GO:0003881 CDP-diacylglycerol-inositol 3-phosphatidyltransferase activity(GO:0003881)
0.1 2.4 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.1 0.9 GO:0046978 TAP1 binding(GO:0046978) TAP2 binding(GO:0046979)
0.1 2.6 GO:0102391 decanoate--CoA ligase activity(GO:0102391)
0.1 0.4 GO:0004967 glucagon receptor activity(GO:0004967)
0.1 0.7 GO:0016018 cyclosporin A binding(GO:0016018)
0.1 1.2 GO:0031545 peptidyl-proline 4-dioxygenase activity(GO:0031545)
0.1 0.6 GO:0016499 orexin receptor activity(GO:0016499)
0.1 1.8 GO:0042301 phosphate ion binding(GO:0042301)
0.1 0.8 GO:0031849 olfactory receptor binding(GO:0031849)
0.1 2.3 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.1 0.4 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
0.1 0.7 GO:0004487 methylenetetrahydrofolate dehydrogenase (NAD+) activity(GO:0004487)
0.1 2.5 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.1 0.3 GO:0004019 adenylosuccinate synthase activity(GO:0004019)
0.1 0.9 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.1 0.3 GO:0099530 PLC activating G-protein coupled glutamate receptor activity(GO:0001639) G-protein coupled receptor activity involved in regulation of postsynaptic membrane potential(GO:0099530)
0.1 1.6 GO:0015245 fatty acid transporter activity(GO:0015245)
0.1 0.3 GO:0008967 phosphoglycolate phosphatase activity(GO:0008967)
0.1 0.5 GO:0016918 retinal binding(GO:0016918)
0.1 0.6 GO:0033142 progesterone receptor binding(GO:0033142)
0.1 2.4 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.1 0.5 GO:0070287 ferritin receptor activity(GO:0070287)
0.1 2.2 GO:0032041 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.1 0.3 GO:0005026 transforming growth factor beta receptor activity, type II(GO:0005026)
0.1 0.3 GO:0004615 phosphomannomutase activity(GO:0004615)
0.1 1.9 GO:0031702 type 1 angiotensin receptor binding(GO:0031702)
0.1 2.4 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
0.1 0.6 GO:0030549 acetylcholine receptor activator activity(GO:0030549)
0.1 0.4 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
0.1 19.0 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.1 1.1 GO:0008556 potassium-transporting ATPase activity(GO:0008556)
0.1 0.2 GO:0004947 bradykinin receptor activity(GO:0004947)
0.1 0.5 GO:0043533 inositol 1,3,4,5 tetrakisphosphate binding(GO:0043533)
0.1 0.6 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.1 1.1 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.1 2.1 GO:0017081 chloride channel regulator activity(GO:0017081)
0.1 2.5 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.1 0.7 GO:0008131 primary amine oxidase activity(GO:0008131)
0.1 3.0 GO:0030506 ankyrin binding(GO:0030506)
0.1 0.5 GO:0004614 phosphoglucomutase activity(GO:0004614)
0.1 2.1 GO:0003951 NAD+ kinase activity(GO:0003951)
0.1 0.5 GO:0042289 MHC class II protein binding(GO:0042289)
0.1 0.4 GO:0004308 exo-alpha-sialidase activity(GO:0004308) alpha-sialidase activity(GO:0016997) exo-alpha-(2->3)-sialidase activity(GO:0052794) exo-alpha-(2->6)-sialidase activity(GO:0052795) exo-alpha-(2->8)-sialidase activity(GO:0052796)
0.1 1.8 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.1 1.9 GO:0015114 phosphate ion transmembrane transporter activity(GO:0015114)
0.1 0.7 GO:0005000 vasopressin receptor activity(GO:0005000)
0.1 0.2 GO:0004133 glycogen debranching enzyme activity(GO:0004133) 4-alpha-glucanotransferase activity(GO:0004134) amylo-alpha-1,6-glucosidase activity(GO:0004135)
0.1 0.3 GO:0004052 arachidonate 12-lipoxygenase activity(GO:0004052)
0.1 2.2 GO:0044769 ATPase activity, coupled to transmembrane movement of ions, rotational mechanism(GO:0044769)
0.1 0.5 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.1 0.8 GO:0019855 calcium channel inhibitor activity(GO:0019855)
0.1 0.3 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.1 2.6 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.1 0.9 GO:0048273 mitogen-activated protein kinase p38 binding(GO:0048273)
0.1 3.2 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.1 0.7 GO:0016888 endodeoxyribonuclease activity, producing 5'-phosphomonoesters(GO:0016888)
0.1 0.6 GO:0015193 L-proline transmembrane transporter activity(GO:0015193)
0.1 1.3 GO:0016805 dipeptidase activity(GO:0016805)
0.1 0.8 GO:0051525 NFAT protein binding(GO:0051525)
0.1 0.3 GO:0042285 xylosyltransferase activity(GO:0042285)
0.1 0.3 GO:0005186 pheromone activity(GO:0005186)
0.1 0.4 GO:0047499 calcium-independent phospholipase A2 activity(GO:0047499)
0.1 2.5 GO:0016831 carboxy-lyase activity(GO:0016831)
0.1 0.8 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.1 3.4 GO:0008395 steroid hydroxylase activity(GO:0008395)
0.0 1.5 GO:0047617 acyl-CoA hydrolase activity(GO:0047617)
0.0 2.3 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.0 0.2 GO:0016742 hydroxymethyl-, formyl- and related transferase activity(GO:0016742)
0.0 0.1 GO:0005143 interleukin-12 receptor binding(GO:0005143)
0.0 0.4 GO:0008504 monoamine transmembrane transporter activity(GO:0008504)
0.0 1.7 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.0 0.3 GO:0001595 angiotensin receptor activity(GO:0001595)
0.0 1.3 GO:0004890 GABA-A receptor activity(GO:0004890)
0.0 0.4 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.0 1.0 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.0 0.2 GO:0034602 oxoglutarate dehydrogenase (NAD+) activity(GO:0034602)
0.0 0.7 GO:0015250 water channel activity(GO:0015250)
0.0 0.9 GO:0004993 G-protein coupled serotonin receptor activity(GO:0004993)
0.0 1.0 GO:0004407 histone deacetylase activity(GO:0004407)
0.0 0.7 GO:0034185 apolipoprotein binding(GO:0034185)
0.0 5.2 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.2 GO:0004703 G-protein coupled receptor kinase activity(GO:0004703)
0.0 0.4 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.0 0.6 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 1.6 GO:0051959 dynein light intermediate chain binding(GO:0051959)
0.0 0.1 GO:0035939 microsatellite binding(GO:0035939)
0.0 5.6 GO:0015293 symporter activity(GO:0015293)
0.0 1.1 GO:0019789 SUMO transferase activity(GO:0019789)
0.0 0.5 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.0 2.0 GO:0017080 sodium channel regulator activity(GO:0017080)
0.0 0.5 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.0 0.5 GO:0050321 tau-protein kinase activity(GO:0050321)
0.0 4.5 GO:0008013 beta-catenin binding(GO:0008013)
0.0 0.1 GO:0046870 cadmium ion binding(GO:0046870)
0.0 2.0 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.0 1.0 GO:0017134 fibroblast growth factor binding(GO:0017134)
0.0 1.7 GO:0005507 copper ion binding(GO:0005507)
0.0 0.9 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.0 0.1 GO:0008241 peptidyl-dipeptidase activity(GO:0008241)
0.0 0.5 GO:0003995 acyl-CoA dehydrogenase activity(GO:0003995)
0.0 0.8 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.0 0.2 GO:0008294 calcium- and calmodulin-responsive adenylate cyclase activity(GO:0008294)
0.0 0.2 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.0 1.7 GO:0003743 translation initiation factor activity(GO:0003743)
0.0 0.9 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.0 0.2 GO:1990247 N6-methyladenosine-containing RNA binding(GO:1990247)
0.0 0.1 GO:0032027 myosin light chain binding(GO:0032027)
0.0 0.5 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.0 0.9 GO:0030552 cAMP binding(GO:0030552)
0.0 0.5 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.8 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 1.3 GO:0015485 cholesterol binding(GO:0015485)
0.0 1.0 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 0.1 GO:0031708 endothelin B receptor binding(GO:0031708)
0.0 0.3 GO:0050811 GABA receptor binding(GO:0050811)
0.0 1.3 GO:0019003 GDP binding(GO:0019003)
0.0 0.1 GO:0070736 protein-glycine ligase activity, initiating(GO:0070736)
0.0 1.5 GO:0035064 methylated histone binding(GO:0035064)
0.0 0.9 GO:0016620 oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor(GO:0016620)
0.0 0.3 GO:0019215 intermediate filament binding(GO:0019215)
0.0 0.3 GO:0015106 bicarbonate transmembrane transporter activity(GO:0015106)
0.0 0.6 GO:0051059 NF-kappaB binding(GO:0051059)
0.0 0.1 GO:0031800 type 3 metabotropic glutamate receptor binding(GO:0031800)
0.0 0.4 GO:0004385 guanylate kinase activity(GO:0004385)
0.0 0.4 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 0.2 GO:0005355 glucose transmembrane transporter activity(GO:0005355)
0.0 0.3 GO:0030957 Tat protein binding(GO:0030957)
0.0 0.1 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873)
0.0 0.1 GO:0031685 adenosine receptor binding(GO:0031685)
0.0 0.1 GO:0004969 histamine receptor activity(GO:0004969)
0.0 1.2 GO:0005249 voltage-gated potassium channel activity(GO:0005249)
0.0 0.6 GO:0015459 potassium channel regulator activity(GO:0015459)
0.0 0.1 GO:0045504 dynein heavy chain binding(GO:0045504)
0.0 0.4 GO:0000217 DNA secondary structure binding(GO:0000217)
0.0 0.0 GO:0034597 phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316) phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity(GO:0034597)
0.0 0.5 GO:0071889 14-3-3 protein binding(GO:0071889)
0.0 0.2 GO:0003993 acid phosphatase activity(GO:0003993)
0.0 0.4 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0 0.9 GO:0005550 pheromone binding(GO:0005550)
0.0 0.1 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.0 0.2 GO:0071855 neuropeptide receptor binding(GO:0071855)
0.0 0.1 GO:0045322 unmethylated CpG binding(GO:0045322)
0.0 0.1 GO:0004972 NMDA glutamate receptor activity(GO:0004972)
0.0 0.1 GO:0051870 methotrexate binding(GO:0051870)
0.0 1.2 GO:0004222 metalloendopeptidase activity(GO:0004222)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 15.5 ST WNT CA2 CYCLIC GMP PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.2 6.0 PID WNT SIGNALING PATHWAY Wnt signaling network
0.2 6.2 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.1 3.8 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.1 1.3 SA G1 AND S PHASES Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.1 6.4 PID FOXO PATHWAY FoxO family signaling
0.1 0.9 PID IL5 PATHWAY IL5-mediated signaling events
0.1 4.1 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II
0.0 0.6 PID ALK2 PATHWAY ALK2 signaling events
0.0 4.1 PID ERBB4 PATHWAY ErbB4 signaling events
0.0 1.2 PID RHODOPSIN PATHWAY Visual signal transduction: Rods
0.0 8.3 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 0.7 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.0 10.1 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 1.7 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.0 2.3 PID CERAMIDE PATHWAY Ceramide signaling pathway
0.0 1.7 PID PI3KCI PATHWAY Class I PI3K signaling events
0.0 1.4 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 1.5 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.0 1.3 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.0 0.9 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.0 0.7 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.0 2.0 PID NOTCH PATHWAY Notch signaling pathway
0.0 0.2 SA TRKA RECEPTOR The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.0 0.2 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.0 0.4 PID IL23 PATHWAY IL23-mediated signaling events
0.0 0.7 PID HEDGEHOG GLI PATHWAY Hedgehog signaling events mediated by Gli proteins
0.0 0.3 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining
0.0 0.2 PID PS1 PATHWAY Presenilin action in Notch and Wnt signaling
0.0 3.8 NABA MATRISOME ASSOCIATED Ensemble of genes encoding ECM-associated proteins including ECM-affilaited proteins, ECM regulators and secreted factors
0.0 0.8 PID MET PATHWAY Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.0 0.5 PID LKB1 PATHWAY LKB1 signaling events
0.0 0.6 PID ARF6 TRAFFICKING PATHWAY Arf6 trafficking events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.8 53.0 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.9 19.9 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.8 12.4 REACTOME INITIAL TRIGGERING OF COMPLEMENT Genes involved in Initial triggering of complement
0.6 46.8 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.5 9.7 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.4 7.6 REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.3 4.5 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 7ALPHA HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol
0.3 5.7 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.3 2.8 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.2 4.8 REACTOME ALPHA LINOLENIC ACID ALA METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.2 7.0 REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.2 21.2 REACTOME AMINO ACID AND OLIGOPEPTIDE SLC TRANSPORTERS Genes involved in Amino acid and oligopeptide SLC transporters
0.2 3.5 REACTOME COMPLEMENT CASCADE Genes involved in Complement cascade
0.2 4.6 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.2 2.7 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.2 2.7 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.2 1.8 REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.1 2.9 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.1 1.4 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
0.1 3.8 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.1 3.3 REACTOME PROLACTIN RECEPTOR SIGNALING Genes involved in Prolactin receptor signaling
0.1 2.4 REACTOME HS GAG DEGRADATION Genes involved in HS-GAG degradation
0.1 2.1 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.1 1.4 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.1 2.4 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.1 3.4 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.1 1.6 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.1 14.7 REACTOME POTASSIUM CHANNELS Genes involved in Potassium Channels
0.1 0.9 REACTOME SEROTONIN RECEPTORS Genes involved in Serotonin receptors
0.1 3.4 REACTOME METAL ION SLC TRANSPORTERS Genes involved in Metal ion SLC transporters
0.1 4.1 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.1 0.8 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.1 3.1 REACTOME STEROID HORMONES Genes involved in Steroid hormones
0.1 1.4 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
0.1 0.4 REACTOME INFLUENZA VIRAL RNA TRANSCRIPTION AND REPLICATION Genes involved in Influenza Viral RNA Transcription and Replication
0.1 1.5 REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.1 4.5 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.1 0.8 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.1 2.2 REACTOME INSULIN RECEPTOR RECYCLING Genes involved in Insulin receptor recycling
0.1 1.5 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.1 2.7 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.1 0.6 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0 0.7 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.0 1.3 REACTOME NUCLEOTIDE LIKE PURINERGIC RECEPTORS Genes involved in Nucleotide-like (purinergic) receptors
0.0 0.8 REACTOME SYNTHESIS OF PC Genes involved in Synthesis of PC
0.0 0.7 REACTOME PHASE1 FUNCTIONALIZATION OF COMPOUNDS Genes involved in Phase 1 - Functionalization of compounds
0.0 0.9 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.0 3.0 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0 1.4 REACTOME REGULATION OF INSULIN SECRETION BY GLUCAGON LIKE PEPTIDE1 Genes involved in Regulation of Insulin Secretion by Glucagon-like Peptide-1
0.0 5.6 REACTOME PPARA ACTIVATES GENE EXPRESSION Genes involved in PPARA Activates Gene Expression
0.0 0.6 REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX Genes involved in CDC6 association with the ORC:origin complex
0.0 1.7 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 0.5 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.0 0.6 REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
0.0 0.5 REACTOME BOTULINUM NEUROTOXICITY Genes involved in Botulinum neurotoxicity
0.0 0.5 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.0 2.6 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 0.4 REACTOME ACYL CHAIN REMODELLING OF PC Genes involved in Acyl chain remodelling of PC
0.0 1.0 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.0 5.0 REACTOME G ALPHA I SIGNALLING EVENTS Genes involved in G alpha (i) signalling events
0.0 1.0 REACTOME REGULATION OF BETA CELL DEVELOPMENT Genes involved in Regulation of beta-cell development
0.0 1.0 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.0 0.2 REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
0.0 1.1 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0 0.6 REACTOME ENOS ACTIVATION AND REGULATION Genes involved in eNOS activation and regulation
0.0 1.4 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0 0.3 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.0 0.4 REACTOME FGFR4 LIGAND BINDING AND ACTIVATION Genes involved in FGFR4 ligand binding and activation
0.0 0.4 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0 0.5 REACTOME RNA POL III TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase III Transcription Termination
0.0 0.5 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 0.8 REACTOME GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.0 1.6 REACTOME PEPTIDE LIGAND BINDING RECEPTORS Genes involved in Peptide ligand-binding receptors
0.0 0.9 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0 0.2 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 0.4 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.0 0.6 REACTOME IL RECEPTOR SHC SIGNALING Genes involved in Interleukin receptor SHC signaling
0.0 0.4 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.0 0.4 REACTOME GLYCEROPHOSPHOLIPID BIOSYNTHESIS Genes involved in Glycerophospholipid biosynthesis
0.0 2.1 REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES Genes involved in Metabolism of amino acids and derivatives
0.0 0.5 REACTOME G ALPHA S SIGNALLING EVENTS Genes involved in G alpha (s) signalling events
0.0 2.6 REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.0 0.1 REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC Genes involved in Formation of tubulin folding intermediates by CCT/TriC