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GSE58827: Dynamics of the Mouse Liver
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Results for Ets1
Z-value: 3.19
Motif logo
Transcription factors associated with Ets1
| Gene Symbol | Gene ID | Gene Info |
|---|---|---|
|
Ets1
|
ENSMUSG00000032035.17 | E26 avian leukemia oncogene 1, 5' domain |
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| Ets1 | mm39_v1_chr9_+_32607301_32607417 | 0.77 | 4.5e-08 | Click! |
Activity profile of Ets1 motif
Sorted Z-values of Ets1 motif
Network of associatons between targets according to the STRING database.
First level regulatory network of Ets1
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 17.6 | 52.9 | GO:0002149 | hypochlorous acid metabolic process(GO:0002148) hypochlorous acid biosynthetic process(GO:0002149) |
| 11.2 | 33.7 | GO:0035606 | peptidyl-cysteine S-trans-nitrosylation(GO:0035606) |
| 9.7 | 29.0 | GO:0070947 | antimicrobial peptide biosynthetic process(GO:0002777) antibacterial peptide biosynthetic process(GO:0002780) neutrophil mediated killing of fungus(GO:0070947) |
| 8.3 | 24.9 | GO:0001807 | regulation of type IV hypersensitivity(GO:0001807) |
| 6.1 | 36.6 | GO:1903336 | endosome localization(GO:0032439) negative regulation of vacuolar transport(GO:1903336) |
| 4.9 | 19.7 | GO:0090116 | C-5 methylation of cytosine(GO:0090116) positive regulation of methylation-dependent chromatin silencing(GO:0090309) |
| 4.5 | 22.5 | GO:0097029 | mature conventional dendritic cell differentiation(GO:0097029) |
| 4.2 | 20.9 | GO:0002752 | cell surface pattern recognition receptor signaling pathway(GO:0002752) |
| 3.8 | 19.1 | GO:0006742 | NADP catabolic process(GO:0006742) |
| 3.8 | 11.4 | GO:0071846 | actin filament debranching(GO:0071846) |
| 3.8 | 11.3 | GO:0045763 | negative regulation of cellular amino acid metabolic process(GO:0045763) |
| 3.6 | 10.7 | GO:0036388 | pre-replicative complex assembly involved in nuclear cell cycle DNA replication(GO:0006267) pre-replicative complex assembly(GO:0036388) DNA replication preinitiation complex assembly(GO:0071163) pre-replicative complex assembly involved in cell cycle DNA replication(GO:1902299) |
| 3.5 | 10.6 | GO:0070318 | positive regulation of G0 to G1 transition(GO:0070318) |
| 3.5 | 10.6 | GO:0006740 | NADPH regeneration(GO:0006740) |
| 3.5 | 10.6 | GO:0002625 | regulation of T cell antigen processing and presentation(GO:0002625) |
| 3.5 | 13.9 | GO:0072385 | minus-end-directed organelle transport along microtubule(GO:0072385) |
| 3.2 | 3.2 | GO:0035666 | TRIF-dependent toll-like receptor signaling pathway(GO:0035666) |
| 3.2 | 28.5 | GO:0002291 | T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell(GO:0002291) |
| 3.0 | 9.0 | GO:0030845 | regulation of inositol-polyphosphate 5-phosphatase activity(GO:0010924) positive regulation of inositol-polyphosphate 5-phosphatase activity(GO:0010925) phospholipase C-inhibiting G-protein coupled receptor signaling pathway(GO:0030845) regulation of cell diameter(GO:0060305) |
| 2.8 | 8.5 | GO:1900195 | positive regulation of oocyte maturation(GO:1900195) |
| 2.8 | 8.5 | GO:0014805 | smooth muscle adaptation(GO:0014805) |
| 2.7 | 24.1 | GO:0030886 | negative regulation of myeloid dendritic cell activation(GO:0030886) |
| 2.6 | 13.1 | GO:1901355 | response to rapamycin(GO:1901355) |
| 2.6 | 20.7 | GO:1904378 | maintenance of unfolded protein(GO:0036506) maintenance of unfolded protein involved in ERAD pathway(GO:1904378) |
| 2.5 | 10.2 | GO:0002433 | immune response-regulating cell surface receptor signaling pathway involved in phagocytosis(GO:0002433) Fc-gamma receptor signaling pathway involved in phagocytosis(GO:0038096) |
| 2.4 | 9.6 | GO:0046898 | response to cycloheximide(GO:0046898) |
| 2.4 | 62.5 | GO:0030213 | hyaluronan biosynthetic process(GO:0030213) |
| 2.4 | 9.6 | GO:0034241 | positive regulation of macrophage fusion(GO:0034241) |
| 2.3 | 9.2 | GO:0070358 | actin polymerization-dependent cell motility(GO:0070358) |
| 2.3 | 9.2 | GO:0010286 | heat acclimation(GO:0010286) |
| 2.2 | 4.4 | GO:0001560 | regulation of cell growth by extracellular stimulus(GO:0001560) |
| 2.2 | 19.4 | GO:0051534 | negative regulation of NFAT protein import into nucleus(GO:0051534) |
| 2.1 | 10.7 | GO:0000454 | snoRNA guided rRNA pseudouridine synthesis(GO:0000454) |
| 2.1 | 20.8 | GO:0010032 | meiotic chromosome condensation(GO:0010032) |
| 2.1 | 8.3 | GO:0002457 | T cell antigen processing and presentation(GO:0002457) |
| 1.9 | 5.8 | GO:0002946 | tRNA C5-cytosine methylation(GO:0002946) |
| 1.9 | 7.4 | GO:0006014 | D-ribose metabolic process(GO:0006014) |
| 1.8 | 10.9 | GO:0003065 | positive regulation of heart rate by epinephrine(GO:0003065) |
| 1.7 | 7.0 | GO:0045659 | negative regulation of neutrophil differentiation(GO:0045659) |
| 1.7 | 6.9 | GO:0060265 | positive regulation of respiratory burst involved in inflammatory response(GO:0060265) |
| 1.7 | 5.2 | GO:0019417 | sulfur oxidation(GO:0019417) |
| 1.7 | 20.2 | GO:0006268 | DNA unwinding involved in DNA replication(GO:0006268) |
| 1.7 | 11.7 | GO:1901977 | negative regulation of cell cycle checkpoint(GO:1901977) negative regulation of DNA damage checkpoint(GO:2000002) |
| 1.6 | 7.8 | GO:0045347 | negative regulation of MHC class II biosynthetic process(GO:0045347) |
| 1.5 | 4.6 | GO:0030043 | actin filament fragmentation(GO:0030043) |
| 1.5 | 12.2 | GO:2000491 | positive regulation of hepatic stellate cell activation(GO:2000491) |
| 1.5 | 6.1 | GO:0042117 | monocyte activation(GO:0042117) |
| 1.5 | 4.5 | GO:0060715 | syncytiotrophoblast cell differentiation involved in labyrinthine layer development(GO:0060715) |
| 1.5 | 7.5 | GO:0072656 | maintenance of protein location in mitochondrion(GO:0072656) |
| 1.5 | 6.0 | GO:0060800 | regulation of cell differentiation involved in embryonic placenta development(GO:0060800) |
| 1.5 | 14.8 | GO:0033632 | regulation of cell-cell adhesion mediated by integrin(GO:0033632) |
| 1.5 | 5.9 | GO:0022007 | neural plate elongation(GO:0014022) convergent extension involved in neural plate elongation(GO:0022007) |
| 1.5 | 4.4 | GO:1904959 | regulation of cytochrome-c oxidase activity(GO:1904959) |
| 1.4 | 13.0 | GO:0032079 | positive regulation of endodeoxyribonuclease activity(GO:0032079) |
| 1.4 | 7.1 | GO:0034085 | establishment of sister chromatid cohesion(GO:0034085) cohesin loading(GO:0071921) regulation of cohesin loading(GO:0071922) |
| 1.4 | 8.5 | GO:0009826 | unidimensional cell growth(GO:0009826) |
| 1.4 | 9.9 | GO:0010936 | negative regulation of macrophage cytokine production(GO:0010936) |
| 1.4 | 26.8 | GO:0019886 | antigen processing and presentation of exogenous peptide antigen via MHC class II(GO:0019886) |
| 1.4 | 1.4 | GO:0032741 | positive regulation of interleukin-18 production(GO:0032741) |
| 1.4 | 27.7 | GO:1900017 | positive regulation of cytokine production involved in inflammatory response(GO:1900017) |
| 1.4 | 19.2 | GO:0000185 | activation of MAPKKK activity(GO:0000185) |
| 1.4 | 2.7 | GO:0061357 | positive regulation of Wnt protein secretion(GO:0061357) |
| 1.4 | 4.1 | GO:0061623 | hexitol metabolic process(GO:0006059) glycolytic process from galactose(GO:0061623) |
| 1.4 | 5.4 | GO:0021812 | neuronal-glial interaction involved in cerebral cortex radial glia guided migration(GO:0021812) |
| 1.3 | 8.1 | GO:0070560 | calcium-mediated signaling using extracellular calcium source(GO:0035585) protein secretion by platelet(GO:0070560) |
| 1.3 | 4.0 | GO:0006427 | histidyl-tRNA aminoacylation(GO:0006427) |
| 1.3 | 4.0 | GO:0000389 | mRNA 3'-splice site recognition(GO:0000389) |
| 1.3 | 14.4 | GO:0006335 | DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723) |
| 1.3 | 10.3 | GO:0033277 | abortive mitotic cell cycle(GO:0033277) |
| 1.3 | 3.8 | GO:0006597 | spermine biosynthetic process(GO:0006597) |
| 1.3 | 9.0 | GO:0003376 | sphingosine-1-phosphate signaling pathway(GO:0003376) |
| 1.3 | 38.3 | GO:2001223 | negative regulation of neuron migration(GO:2001223) |
| 1.3 | 3.8 | GO:1904975 | response to bleomycin(GO:1904975) cellular response to bleomycin(GO:1904976) |
| 1.3 | 7.6 | GO:0002528 | regulation of vascular permeability involved in acute inflammatory response(GO:0002528) |
| 1.3 | 3.8 | GO:0031554 | regulation of DNA-templated transcription, termination(GO:0031554) |
| 1.3 | 6.3 | GO:0030576 | Cajal body organization(GO:0030576) |
| 1.3 | 8.8 | GO:0016266 | O-glycan processing(GO:0016266) |
| 1.3 | 3.8 | GO:2000097 | regulation of smooth muscle cell-matrix adhesion(GO:2000097) |
| 1.3 | 3.8 | GO:0070476 | rRNA (guanine-N7)-methylation(GO:0070476) |
| 1.2 | 1.2 | GO:2000393 | negative regulation of lamellipodium morphogenesis(GO:2000393) |
| 1.2 | 4.9 | GO:1904425 | negative regulation of GTP binding(GO:1904425) |
| 1.2 | 7.2 | GO:1901526 | positive regulation of macromitophagy(GO:1901526) positive regulation of mitophagy in response to mitochondrial depolarization(GO:1904925) |
| 1.2 | 3.6 | GO:0002940 | tRNA N2-guanine methylation(GO:0002940) |
| 1.2 | 7.2 | GO:1901228 | positive regulation of transcription from RNA polymerase II promoter involved in heart development(GO:1901228) |
| 1.2 | 16.6 | GO:0046645 | positive regulation of gamma-delta T cell differentiation(GO:0045588) positive regulation of gamma-delta T cell activation(GO:0046645) |
| 1.2 | 5.9 | GO:0046075 | dTTP biosynthetic process(GO:0006235) pyrimidine deoxyribonucleoside triphosphate biosynthetic process(GO:0009212) dTTP metabolic process(GO:0046075) |
| 1.2 | 23.6 | GO:1904816 | positive regulation of protein localization to chromosome, telomeric region(GO:1904816) |
| 1.2 | 3.5 | GO:1990173 | protein localization to nucleoplasm(GO:1990173) |
| 1.2 | 21.1 | GO:0002283 | neutrophil activation involved in immune response(GO:0002283) |
| 1.2 | 15.1 | GO:0051014 | actin filament severing(GO:0051014) |
| 1.2 | 9.2 | GO:0032237 | activation of store-operated calcium channel activity(GO:0032237) |
| 1.1 | 2.2 | GO:0072708 | response to sorbitol(GO:0072708) |
| 1.1 | 1.1 | GO:0045905 | translational frameshifting(GO:0006452) positive regulation of translational termination(GO:0045905) |
| 1.1 | 5.5 | GO:1902167 | positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:1902167) |
| 1.1 | 17.3 | GO:0043485 | endosome to melanosome transport(GO:0035646) endosome to pigment granule transport(GO:0043485) pigment granule maturation(GO:0048757) |
| 1.1 | 11.8 | GO:0006398 | mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398) |
| 1.1 | 12.9 | GO:0016191 | synaptic vesicle uncoating(GO:0016191) |
| 1.1 | 5.3 | GO:0048478 | replication fork protection(GO:0048478) |
| 1.1 | 3.2 | GO:1903972 | regulation of macrophage colony-stimulating factor signaling pathway(GO:1902226) regulation of response to macrophage colony-stimulating factor(GO:1903969) regulation of cellular response to macrophage colony-stimulating factor stimulus(GO:1903972) |
| 1.0 | 11.5 | GO:0090232 | positive regulation of spindle checkpoint(GO:0090232) |
| 1.0 | 10.4 | GO:0051388 | positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388) |
| 1.0 | 2.1 | GO:1900368 | regulation of RNA interference(GO:1900368) |
| 1.0 | 17.2 | GO:0033148 | positive regulation of intracellular estrogen receptor signaling pathway(GO:0033148) |
| 1.0 | 3.0 | GO:2000813 | negative regulation of barbed-end actin filament capping(GO:2000813) |
| 1.0 | 4.0 | GO:0006269 | DNA replication, synthesis of RNA primer(GO:0006269) |
| 1.0 | 6.0 | GO:0051031 | tRNA transport(GO:0051031) |
| 1.0 | 4.9 | GO:0002352 | B cell negative selection(GO:0002352) |
| 1.0 | 3.9 | GO:1903527 | positive regulation of membrane tubulation(GO:1903527) |
| 1.0 | 7.8 | GO:1904668 | positive regulation of ubiquitin protein ligase activity(GO:1904668) |
| 1.0 | 7.8 | GO:0032532 | regulation of microvillus length(GO:0032532) |
| 1.0 | 7.7 | GO:0070294 | renal sodium ion absorption(GO:0070294) |
| 1.0 | 2.9 | GO:0006407 | rRNA export from nucleus(GO:0006407) |
| 0.9 | 2.8 | GO:0099526 | presynaptic signal transduction(GO:0098928) presynapse to nucleus signaling pathway(GO:0099526) |
| 0.9 | 2.8 | GO:1902626 | assembly of large subunit precursor of preribosome(GO:1902626) |
| 0.9 | 3.8 | GO:0000973 | posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000973) |
| 0.9 | 6.6 | GO:0075525 | viral translational termination-reinitiation(GO:0075525) |
| 0.9 | 2.8 | GO:0010767 | regulation of transcription from RNA polymerase II promoter in response to UV-induced DNA damage(GO:0010767) |
| 0.9 | 3.7 | GO:1990091 | positive regulation of satellite cell activation involved in skeletal muscle regeneration(GO:0014718) sodium-dependent self proteolysis(GO:1990091) |
| 0.9 | 9.1 | GO:0051256 | mitotic spindle midzone assembly(GO:0051256) |
| 0.9 | 4.6 | GO:0046501 | protoporphyrinogen IX metabolic process(GO:0046501) |
| 0.9 | 17.3 | GO:0051988 | regulation of attachment of spindle microtubules to kinetochore(GO:0051988) |
| 0.9 | 5.4 | GO:2000434 | regulation of protein neddylation(GO:2000434) negative regulation of protein neddylation(GO:2000435) |
| 0.9 | 2.7 | GO:0097045 | activation of blood coagulation via clotting cascade(GO:0002543) phosphatidylserine exposure on blood platelet(GO:0097045) |
| 0.9 | 3.6 | GO:0042998 | positive regulation of Golgi to plasma membrane protein transport(GO:0042998) positive regulation of establishment of protein localization to plasma membrane(GO:0090004) |
| 0.9 | 7.1 | GO:0002432 | granuloma formation(GO:0002432) |
| 0.9 | 1.8 | GO:0010847 | regulation of chromatin assembly(GO:0010847) |
| 0.9 | 2.7 | GO:0032661 | regulation of interleukin-18 production(GO:0032661) |
| 0.9 | 3.5 | GO:0046084 | adenine salvage(GO:0006168) purine nucleobase salvage(GO:0043096) adenine metabolic process(GO:0046083) adenine biosynthetic process(GO:0046084) |
| 0.9 | 2.6 | GO:0000720 | pyrimidine dimer repair by nucleotide-excision repair(GO:0000720) nucleotide-excision repair, DNA incision, 3'-to lesion(GO:0006295) |
| 0.9 | 11.4 | GO:0050862 | positive regulation of T cell receptor signaling pathway(GO:0050862) |
| 0.9 | 6.9 | GO:0072378 | blood coagulation, fibrin clot formation(GO:0072378) |
| 0.8 | 4.2 | GO:1903898 | negative regulation of PERK-mediated unfolded protein response(GO:1903898) |
| 0.8 | 2.5 | GO:0032241 | positive regulation of nucleobase-containing compound transport(GO:0032241) |
| 0.8 | 14.4 | GO:0006654 | phosphatidic acid biosynthetic process(GO:0006654) |
| 0.8 | 14.3 | GO:0033234 | negative regulation of protein sumoylation(GO:0033234) |
| 0.8 | 5.0 | GO:1901314 | negative regulation of histone ubiquitination(GO:0033183) negative regulation of protein K63-linked ubiquitination(GO:1900045) regulation of histone H2A K63-linked ubiquitination(GO:1901314) negative regulation of histone H2A K63-linked ubiquitination(GO:1901315) negative regulation of protein polyubiquitination(GO:1902915) |
| 0.8 | 9.0 | GO:0033120 | positive regulation of RNA splicing(GO:0033120) |
| 0.8 | 4.1 | GO:0002309 | T cell proliferation involved in immune response(GO:0002309) |
| 0.8 | 4.9 | GO:0036066 | protein O-linked fucosylation(GO:0036066) |
| 0.8 | 4.1 | GO:0070945 | neutrophil mediated killing of gram-negative bacterium(GO:0070945) |
| 0.8 | 2.4 | GO:0042128 | nitrate assimilation(GO:0042128) |
| 0.8 | 5.7 | GO:0051533 | positive regulation of NFAT protein import into nucleus(GO:0051533) |
| 0.8 | 28.8 | GO:0048268 | clathrin coat assembly(GO:0048268) |
| 0.8 | 16.0 | GO:0061179 | negative regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061179) |
| 0.8 | 19.9 | GO:0000028 | ribosomal small subunit assembly(GO:0000028) |
| 0.8 | 4.8 | GO:2000348 | regulation of CD40 signaling pathway(GO:2000348) |
| 0.8 | 3.1 | GO:0072355 | histone H3-T3 phosphorylation(GO:0072355) |
| 0.8 | 9.4 | GO:0070493 | thrombin receptor signaling pathway(GO:0070493) |
| 0.8 | 7.7 | GO:0006362 | transcription elongation from RNA polymerase I promoter(GO:0006362) |
| 0.8 | 1.5 | GO:0036245 | cellular response to menadione(GO:0036245) |
| 0.7 | 3.7 | GO:0000447 | endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000447) |
| 0.7 | 2.2 | GO:2001160 | regulation of histone H3-K79 methylation(GO:2001160) |
| 0.7 | 2.2 | GO:0007225 | patched ligand maturation(GO:0007225) signal maturation(GO:0035638) |
| 0.7 | 5.8 | GO:0010897 | negative regulation of triglyceride catabolic process(GO:0010897) |
| 0.7 | 2.9 | GO:0071348 | cellular response to interleukin-11(GO:0071348) |
| 0.7 | 9.4 | GO:0030277 | maintenance of gastrointestinal epithelium(GO:0030277) |
| 0.7 | 6.3 | GO:0032494 | response to peptidoglycan(GO:0032494) |
| 0.7 | 2.8 | GO:0021993 | initiation of neural tube closure(GO:0021993) |
| 0.7 | 4.2 | GO:0002322 | B cell proliferation involved in immune response(GO:0002322) |
| 0.7 | 1.4 | GO:0045362 | regulation of interleukin-1 biosynthetic process(GO:0045360) positive regulation of interleukin-1 biosynthetic process(GO:0045362) |
| 0.7 | 18.7 | GO:0032460 | negative regulation of protein oligomerization(GO:0032460) |
| 0.7 | 14.9 | GO:0006656 | phosphatidylcholine biosynthetic process(GO:0006656) |
| 0.7 | 2.7 | GO:0032887 | mitotic spindle elongation(GO:0000022) regulation of spindle elongation(GO:0032887) regulation of mitotic spindle elongation(GO:0032888) anastral spindle assembly(GO:0055048) protein localization to spindle pole body(GO:0071988) regulation of protein localization to spindle pole body(GO:1902363) positive regulation of protein localization to spindle pole body(GO:1902365) positive regulation of mitotic spindle elongation(GO:1902846) |
| 0.7 | 2.0 | GO:0032066 | nucleolus to nucleoplasm transport(GO:0032066) |
| 0.7 | 2.0 | GO:0018199 | peptidyl-glutamine modification(GO:0018199) |
| 0.7 | 7.4 | GO:0070236 | negative regulation of activation-induced cell death of T cells(GO:0070236) |
| 0.7 | 10.0 | GO:0007213 | G-protein coupled acetylcholine receptor signaling pathway(GO:0007213) |
| 0.7 | 2.0 | GO:1903378 | positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903378) |
| 0.7 | 3.3 | GO:0042631 | cellular response to water deprivation(GO:0042631) |
| 0.6 | 5.2 | GO:1901097 | negative regulation of autophagosome maturation(GO:1901097) |
| 0.6 | 0.6 | GO:0046619 | optic placode formation(GO:0001743) optic placode formation involved in camera-type eye formation(GO:0046619) |
| 0.6 | 11.0 | GO:0000083 | regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083) |
| 0.6 | 2.5 | GO:0006290 | pyrimidine dimer repair(GO:0006290) |
| 0.6 | 3.8 | GO:1904874 | positive regulation of telomerase RNA localization to Cajal body(GO:1904874) |
| 0.6 | 5.1 | GO:0030263 | apoptotic chromosome condensation(GO:0030263) |
| 0.6 | 13.8 | GO:0050913 | sensory perception of bitter taste(GO:0050913) |
| 0.6 | 6.2 | GO:0002903 | negative regulation of B cell apoptotic process(GO:0002903) |
| 0.6 | 2.5 | GO:0006436 | tryptophanyl-tRNA aminoacylation(GO:0006436) |
| 0.6 | 8.0 | GO:0032785 | negative regulation of DNA-templated transcription, elongation(GO:0032785) |
| 0.6 | 0.6 | GO:0000912 | assembly of actomyosin apparatus involved in cytokinesis(GO:0000912) actomyosin contractile ring assembly(GO:0000915) actomyosin contractile ring organization(GO:0044837) |
| 0.6 | 9.8 | GO:0034498 | early endosome to Golgi transport(GO:0034498) |
| 0.6 | 1.8 | GO:0044849 | estrous cycle(GO:0044849) |
| 0.6 | 11.4 | GO:0045292 | mRNA cis splicing, via spliceosome(GO:0045292) |
| 0.6 | 4.2 | GO:0043654 | recognition of apoptotic cell(GO:0043654) |
| 0.6 | 1.8 | GO:0071460 | cellular response to cell-matrix adhesion(GO:0071460) |
| 0.6 | 1.2 | GO:0010726 | positive regulation of hydrogen peroxide metabolic process(GO:0010726) |
| 0.6 | 2.4 | GO:0060830 | ciliary receptor clustering involved in smoothened signaling pathway(GO:0060830) |
| 0.6 | 2.3 | GO:1904569 | regulation of selenocysteine incorporation(GO:1904569) |
| 0.6 | 4.6 | GO:1900262 | regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264) |
| 0.6 | 5.2 | GO:0090070 | positive regulation of ribosome biogenesis(GO:0090070) positive regulation of rRNA processing(GO:2000234) |
| 0.6 | 3.5 | GO:0006297 | nucleotide-excision repair, DNA gap filling(GO:0006297) |
| 0.6 | 2.9 | GO:0032831 | regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation(GO:0032829) positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation(GO:0032831) |
| 0.6 | 1.7 | GO:0007439 | ectodermal digestive tract development(GO:0007439) embryonic ectodermal digestive tract development(GO:0048611) |
| 0.6 | 1.7 | GO:0000349 | generation of catalytic spliceosome for first transesterification step(GO:0000349) |
| 0.6 | 27.8 | GO:0006284 | base-excision repair(GO:0006284) |
| 0.6 | 2.3 | GO:0036258 | multivesicular body assembly(GO:0036258) |
| 0.6 | 3.9 | GO:0032811 | cyclooxygenase pathway(GO:0019371) negative regulation of epinephrine secretion(GO:0032811) maintenance of blood-brain barrier(GO:0035633) |
| 0.6 | 6.7 | GO:0019800 | peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800) |
| 0.6 | 1.7 | GO:0061511 | centriole elongation(GO:0061511) |
| 0.6 | 3.9 | GO:0090521 | glomerular visceral epithelial cell migration(GO:0090521) |
| 0.5 | 1.6 | GO:0019389 | glucuronoside metabolic process(GO:0019389) |
| 0.5 | 5.4 | GO:0061484 | hematopoietic stem cell homeostasis(GO:0061484) |
| 0.5 | 2.1 | GO:1901860 | positive regulation of mitochondrial DNA metabolic process(GO:1901860) |
| 0.5 | 1.1 | GO:1904970 | brush border assembly(GO:1904970) |
| 0.5 | 2.1 | GO:0001928 | regulation of exocyst assembly(GO:0001928) |
| 0.5 | 4.1 | GO:1903504 | regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090266) regulation of mitotic spindle checkpoint(GO:1903504) |
| 0.5 | 2.6 | GO:0010836 | negative regulation of protein ADP-ribosylation(GO:0010836) |
| 0.5 | 12.2 | GO:0042730 | fibrinolysis(GO:0042730) |
| 0.5 | 2.5 | GO:2001280 | positive regulation of prostaglandin biosynthetic process(GO:0031394) positive regulation of unsaturated fatty acid biosynthetic process(GO:2001280) |
| 0.5 | 2.0 | GO:1990481 | mRNA pseudouridine synthesis(GO:1990481) |
| 0.5 | 1.0 | GO:1904578 | response to thapsigargin(GO:1904578) cellular response to thapsigargin(GO:1904579) |
| 0.5 | 13.0 | GO:2000369 | regulation of clathrin-mediated endocytosis(GO:2000369) |
| 0.5 | 6.8 | GO:0001833 | inner cell mass cell proliferation(GO:0001833) |
| 0.5 | 2.9 | GO:1904796 | regulation of core promoter binding(GO:1904796) |
| 0.5 | 1.5 | GO:0048619 | embryonic genitalia morphogenesis(GO:0030538) embryonic hindgut morphogenesis(GO:0048619) |
| 0.5 | 4.4 | GO:0048680 | positive regulation of axon regeneration(GO:0048680) |
| 0.5 | 3.9 | GO:0006265 | DNA topological change(GO:0006265) |
| 0.5 | 17.8 | GO:1903146 | regulation of mitophagy(GO:1903146) |
| 0.5 | 5.8 | GO:0045651 | positive regulation of macrophage differentiation(GO:0045651) |
| 0.5 | 4.8 | GO:2000401 | regulation of lymphocyte migration(GO:2000401) |
| 0.5 | 1.9 | GO:2000210 | positive regulation of anoikis(GO:2000210) |
| 0.5 | 0.9 | GO:0060368 | regulation of Fc receptor mediated stimulatory signaling pathway(GO:0060368) |
| 0.5 | 0.9 | GO:2000017 | positive regulation of determination of dorsal identity(GO:2000017) |
| 0.5 | 2.3 | GO:1902340 | telomeric heterochromatin assembly(GO:0031509) negative regulation of chromosome condensation(GO:1902340) |
| 0.5 | 1.4 | GO:0034970 | histone H3-R2 methylation(GO:0034970) |
| 0.5 | 1.8 | GO:1901165 | positive regulation of trophoblast cell migration(GO:1901165) |
| 0.4 | 13.5 | GO:0019731 | antibacterial humoral response(GO:0019731) |
| 0.4 | 6.2 | GO:0007016 | cytoskeletal anchoring at plasma membrane(GO:0007016) |
| 0.4 | 3.5 | GO:0070475 | rRNA base methylation(GO:0070475) |
| 0.4 | 2.2 | GO:0042412 | taurine biosynthetic process(GO:0042412) |
| 0.4 | 2.2 | GO:2001168 | regulation of histone H2B ubiquitination(GO:2001166) positive regulation of histone H2B ubiquitination(GO:2001168) |
| 0.4 | 7.8 | GO:0033601 | positive regulation of mammary gland epithelial cell proliferation(GO:0033601) |
| 0.4 | 10.9 | GO:0010458 | exit from mitosis(GO:0010458) |
| 0.4 | 15.1 | GO:0000387 | spliceosomal snRNP assembly(GO:0000387) |
| 0.4 | 1.2 | GO:1904092 | regulation of autophagic cell death(GO:1904092) negative regulation of autophagic cell death(GO:1904093) |
| 0.4 | 9.1 | GO:0045730 | respiratory burst(GO:0045730) |
| 0.4 | 4.5 | GO:1900029 | positive regulation of ruffle assembly(GO:1900029) |
| 0.4 | 1.2 | GO:1901978 | positive regulation of cell cycle checkpoint(GO:1901978) |
| 0.4 | 0.4 | GO:0035801 | adrenal cortex development(GO:0035801) adrenal cortex formation(GO:0035802) |
| 0.4 | 1.6 | GO:0098792 | xenophagy(GO:0098792) |
| 0.4 | 14.6 | GO:0060236 | regulation of mitotic spindle organization(GO:0060236) |
| 0.4 | 2.4 | GO:0032596 | protein transport into membrane raft(GO:0032596) |
| 0.4 | 19.9 | GO:0015804 | neutral amino acid transport(GO:0015804) |
| 0.4 | 16.1 | GO:0045737 | positive regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045737) |
| 0.4 | 11.7 | GO:0030539 | male genitalia development(GO:0030539) |
| 0.4 | 3.1 | GO:0097647 | calcitonin family receptor signaling pathway(GO:0097646) amylin receptor signaling pathway(GO:0097647) |
| 0.4 | 6.5 | GO:0050930 | induction of positive chemotaxis(GO:0050930) |
| 0.4 | 3.8 | GO:0032485 | regulation of Ral protein signal transduction(GO:0032485) |
| 0.4 | 14.8 | GO:0006779 | porphyrin-containing compound biosynthetic process(GO:0006779) |
| 0.4 | 6.8 | GO:0002726 | positive regulation of T cell cytokine production(GO:0002726) |
| 0.4 | 1.9 | GO:0090034 | regulation of chaperone-mediated protein complex assembly(GO:0090034) positive regulation of chaperone-mediated protein complex assembly(GO:0090035) |
| 0.4 | 21.4 | GO:0046329 | negative regulation of JNK cascade(GO:0046329) |
| 0.4 | 2.2 | GO:1900245 | positive regulation of MDA-5 signaling pathway(GO:1900245) |
| 0.4 | 9.6 | GO:0038092 | nodal signaling pathway(GO:0038092) |
| 0.4 | 6.2 | GO:0071578 | zinc II ion transmembrane import(GO:0071578) |
| 0.4 | 6.5 | GO:0090110 | cargo loading into COPII-coated vesicle(GO:0090110) |
| 0.4 | 3.6 | GO:0042790 | transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:0042790) |
| 0.4 | 2.9 | GO:0036260 | 7-methylguanosine RNA capping(GO:0009452) RNA capping(GO:0036260) |
| 0.4 | 1.4 | GO:1903758 | regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903756) negative regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903758) |
| 0.3 | 1.0 | GO:0051659 | maintenance of mitochondrion location(GO:0051659) |
| 0.3 | 16.1 | GO:0000281 | mitotic cytokinesis(GO:0000281) |
| 0.3 | 4.8 | GO:0080009 | mRNA methylation(GO:0080009) |
| 0.3 | 2.7 | GO:0007000 | nucleolus organization(GO:0007000) |
| 0.3 | 1.4 | GO:0033182 | regulation of histone ubiquitination(GO:0033182) |
| 0.3 | 3.0 | GO:0035562 | negative regulation of chromatin binding(GO:0035562) |
| 0.3 | 2.0 | GO:0040010 | positive regulation of growth rate(GO:0040010) |
| 0.3 | 1.6 | GO:0006701 | progesterone biosynthetic process(GO:0006701) |
| 0.3 | 1.6 | GO:0032053 | ciliary basal body organization(GO:0032053) |
| 0.3 | 1.6 | GO:0006933 | negative regulation of cell adhesion involved in substrate-bound cell migration(GO:0006933) |
| 0.3 | 2.9 | GO:0036309 | protein localization to M-band(GO:0036309) protein localization to T-tubule(GO:0036371) |
| 0.3 | 2.2 | GO:0032229 | negative regulation of synaptic transmission, GABAergic(GO:0032229) |
| 0.3 | 4.7 | GO:0035970 | peptidyl-threonine dephosphorylation(GO:0035970) |
| 0.3 | 0.9 | GO:0032792 | negative regulation of CREB transcription factor activity(GO:0032792) |
| 0.3 | 1.6 | GO:0017183 | peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183) |
| 0.3 | 7.1 | GO:0071157 | negative regulation of cell cycle arrest(GO:0071157) |
| 0.3 | 23.3 | GO:0045761 | regulation of adenylate cyclase activity(GO:0045761) |
| 0.3 | 2.5 | GO:0010626 | negative regulation of Schwann cell proliferation(GO:0010626) |
| 0.3 | 2.5 | GO:0033210 | leptin-mediated signaling pathway(GO:0033210) |
| 0.3 | 1.5 | GO:0034472 | snRNA 3'-end processing(GO:0034472) |
| 0.3 | 3.7 | GO:1904776 | regulation of protein localization to cell cortex(GO:1904776) positive regulation of protein localization to cell cortex(GO:1904778) |
| 0.3 | 2.4 | GO:0090091 | positive regulation of extracellular matrix disassembly(GO:0090091) |
| 0.3 | 9.2 | GO:0050869 | negative regulation of B cell activation(GO:0050869) |
| 0.3 | 6.0 | GO:0060707 | trophoblast giant cell differentiation(GO:0060707) |
| 0.3 | 1.8 | GO:0000738 | DNA catabolic process, exonucleolytic(GO:0000738) |
| 0.3 | 2.6 | GO:0035021 | negative regulation of Rac protein signal transduction(GO:0035021) |
| 0.3 | 0.6 | GO:0070889 | platelet alpha granule organization(GO:0070889) |
| 0.3 | 1.7 | GO:0001955 | blood vessel maturation(GO:0001955) |
| 0.3 | 2.0 | GO:0090161 | Golgi ribbon formation(GO:0090161) |
| 0.3 | 25.6 | GO:0000910 | cytokinesis(GO:0000910) |
| 0.3 | 3.2 | GO:0000183 | chromatin silencing at rDNA(GO:0000183) |
| 0.3 | 1.4 | GO:0070213 | protein auto-ADP-ribosylation(GO:0070213) |
| 0.3 | 0.6 | GO:1902255 | positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator(GO:1902255) |
| 0.3 | 13.0 | GO:0010501 | RNA secondary structure unwinding(GO:0010501) |
| 0.3 | 1.1 | GO:0050859 | negative regulation of B cell receptor signaling pathway(GO:0050859) |
| 0.3 | 8.3 | GO:0000413 | protein peptidyl-prolyl isomerization(GO:0000413) |
| 0.3 | 0.6 | GO:0010908 | regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010908) positive regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010909) |
| 0.3 | 2.7 | GO:0090037 | positive regulation of protein kinase C signaling(GO:0090037) |
| 0.3 | 3.5 | GO:0002002 | regulation of angiotensin levels in blood(GO:0002002) |
| 0.3 | 2.7 | GO:0030206 | chondroitin sulfate biosynthetic process(GO:0030206) |
| 0.3 | 3.5 | GO:0046007 | negative regulation of activated T cell proliferation(GO:0046007) |
| 0.3 | 27.4 | GO:0030168 | platelet activation(GO:0030168) |
| 0.3 | 4.5 | GO:1900027 | regulation of ruffle assembly(GO:1900027) |
| 0.3 | 2.9 | GO:0035878 | nail development(GO:0035878) |
| 0.3 | 1.0 | GO:0060279 | positive regulation of ovulation(GO:0060279) |
| 0.3 | 9.4 | GO:0048025 | negative regulation of mRNA splicing, via spliceosome(GO:0048025) |
| 0.3 | 4.2 | GO:0033033 | negative regulation of myeloid cell apoptotic process(GO:0033033) |
| 0.3 | 5.7 | GO:0030225 | macrophage differentiation(GO:0030225) |
| 0.3 | 4.1 | GO:0070935 | 3'-UTR-mediated mRNA stabilization(GO:0070935) |
| 0.3 | 2.3 | GO:0031087 | deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087) |
| 0.3 | 1.5 | GO:0033140 | negative regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033140) |
| 0.3 | 6.6 | GO:0045954 | positive regulation of natural killer cell mediated immunity(GO:0002717) positive regulation of natural killer cell mediated cytotoxicity(GO:0045954) |
| 0.3 | 0.5 | GO:1990791 | dorsal root ganglion development(GO:1990791) |
| 0.3 | 1.8 | GO:0045721 | negative regulation of gluconeogenesis(GO:0045721) |
| 0.3 | 9.3 | GO:0035411 | catenin import into nucleus(GO:0035411) |
| 0.3 | 2.5 | GO:2000741 | positive regulation of mesenchymal stem cell differentiation(GO:2000741) |
| 0.2 | 3.0 | GO:0072600 | establishment of protein localization to Golgi(GO:0072600) |
| 0.2 | 1.5 | GO:1901529 | positive regulation of anion channel activity(GO:1901529) |
| 0.2 | 1.5 | GO:2000270 | negative regulation of fibroblast apoptotic process(GO:2000270) |
| 0.2 | 10.9 | GO:0042274 | ribosomal small subunit biogenesis(GO:0042274) |
| 0.2 | 1.4 | GO:1901187 | regulation of ephrin receptor signaling pathway(GO:1901187) |
| 0.2 | 2.8 | GO:0051415 | interphase microtubule nucleation by interphase microtubule organizing center(GO:0051415) microtubule nucleation by microtubule organizing center(GO:0051418) |
| 0.2 | 1.4 | GO:0098535 | de novo centriole assembly(GO:0098535) |
| 0.2 | 0.7 | GO:1902774 | late endosome to lysosome transport(GO:1902774) |
| 0.2 | 1.8 | GO:0060261 | positive regulation of transcription initiation from RNA polymerase II promoter(GO:0060261) |
| 0.2 | 12.0 | GO:0006506 | GPI anchor biosynthetic process(GO:0006506) |
| 0.2 | 1.4 | GO:0070940 | dephosphorylation of RNA polymerase II C-terminal domain(GO:0070940) |
| 0.2 | 2.2 | GO:0001842 | neural fold formation(GO:0001842) |
| 0.2 | 17.5 | GO:0045576 | mast cell activation(GO:0045576) |
| 0.2 | 2.6 | GO:0071850 | mitotic cell cycle arrest(GO:0071850) |
| 0.2 | 0.9 | GO:0014707 | branchiomeric skeletal muscle development(GO:0014707) |
| 0.2 | 0.6 | GO:2000836 | positive regulation of androgen secretion(GO:2000836) positive regulation of testosterone secretion(GO:2000845) |
| 0.2 | 1.5 | GO:0042796 | snRNA transcription from RNA polymerase III promoter(GO:0042796) |
| 0.2 | 0.9 | GO:0099590 | neurotransmitter receptor internalization(GO:0099590) |
| 0.2 | 5.7 | GO:0006301 | postreplication repair(GO:0006301) |
| 0.2 | 13.8 | GO:0002181 | cytoplasmic translation(GO:0002181) |
| 0.2 | 4.1 | GO:0046827 | positive regulation of protein export from nucleus(GO:0046827) |
| 0.2 | 0.6 | GO:0000491 | small nucleolar ribonucleoprotein complex assembly(GO:0000491) |
| 0.2 | 1.6 | GO:0051131 | chaperone-mediated protein complex assembly(GO:0051131) |
| 0.2 | 1.2 | GO:0000972 | transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000972) |
| 0.2 | 1.0 | GO:0009597 | detection of virus(GO:0009597) |
| 0.2 | 0.6 | GO:0042256 | mature ribosome assembly(GO:0042256) |
| 0.2 | 9.1 | GO:0006378 | mRNA polyadenylation(GO:0006378) RNA polyadenylation(GO:0043631) |
| 0.2 | 2.8 | GO:0001522 | pseudouridine synthesis(GO:0001522) |
| 0.2 | 2.4 | GO:0007008 | outer mitochondrial membrane organization(GO:0007008) |
| 0.2 | 0.6 | GO:0048936 | peripheral nervous system neuron axonogenesis(GO:0048936) |
| 0.2 | 0.8 | GO:1903774 | positive regulation of viral budding via host ESCRT complex(GO:1903774) |
| 0.2 | 2.4 | GO:0031297 | replication fork processing(GO:0031297) DNA-dependent DNA replication maintenance of fidelity(GO:0045005) |
| 0.2 | 0.6 | GO:0038156 | interleukin-3-mediated signaling pathway(GO:0038156) |
| 0.2 | 3.7 | GO:0006896 | Golgi to vacuole transport(GO:0006896) |
| 0.2 | 2.0 | GO:0097011 | cellular response to granulocyte macrophage colony-stimulating factor stimulus(GO:0097011) |
| 0.2 | 0.9 | GO:1904953 | Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation(GO:1904953) |
| 0.2 | 2.1 | GO:1900119 | positive regulation of execution phase of apoptosis(GO:1900119) |
| 0.2 | 7.4 | GO:0016239 | positive regulation of macroautophagy(GO:0016239) |
| 0.2 | 6.9 | GO:0045746 | negative regulation of Notch signaling pathway(GO:0045746) |
| 0.2 | 1.0 | GO:0035542 | regulation of SNARE complex assembly(GO:0035542) |
| 0.2 | 2.3 | GO:0046825 | regulation of protein export from nucleus(GO:0046825) |
| 0.2 | 2.9 | GO:0046339 | diacylglycerol metabolic process(GO:0046339) |
| 0.2 | 0.8 | GO:2000623 | regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623) |
| 0.2 | 0.8 | GO:0006420 | arginyl-tRNA aminoacylation(GO:0006420) |
| 0.2 | 0.6 | GO:0001827 | inner cell mass cell fate commitment(GO:0001827) |
| 0.2 | 15.0 | GO:2000117 | negative regulation of cysteine-type endopeptidase activity(GO:2000117) |
| 0.2 | 3.5 | GO:0010569 | regulation of double-strand break repair via homologous recombination(GO:0010569) |
| 0.2 | 18.5 | GO:0030183 | B cell differentiation(GO:0030183) |
| 0.2 | 0.5 | GO:0006435 | threonyl-tRNA aminoacylation(GO:0006435) |
| 0.2 | 2.0 | GO:0051044 | positive regulation of membrane protein ectodomain proteolysis(GO:0051044) |
| 0.2 | 5.0 | GO:0006611 | protein export from nucleus(GO:0006611) |
| 0.2 | 5.2 | GO:0072678 | T cell migration(GO:0072678) |
| 0.2 | 25.3 | GO:0042254 | ribosome biogenesis(GO:0042254) |
| 0.2 | 5.9 | GO:0051123 | RNA polymerase II transcriptional preinitiation complex assembly(GO:0051123) |
| 0.2 | 2.2 | GO:0035630 | bone mineralization involved in bone maturation(GO:0035630) |
| 0.2 | 3.7 | GO:0006744 | ubiquinone metabolic process(GO:0006743) ubiquinone biosynthetic process(GO:0006744) |
| 0.2 | 1.5 | GO:0000963 | mitochondrial RNA processing(GO:0000963) |
| 0.2 | 0.9 | GO:0009303 | rRNA transcription(GO:0009303) |
| 0.2 | 8.2 | GO:0006730 | one-carbon metabolic process(GO:0006730) |
| 0.2 | 3.2 | GO:0070918 | dsRNA fragmentation(GO:0031050) production of miRNAs involved in gene silencing by miRNA(GO:0035196) production of small RNA involved in gene silencing by RNA(GO:0070918) |
| 0.1 | 0.4 | GO:0021570 | rhombomere 3 development(GO:0021569) rhombomere 4 development(GO:0021570) rhombomere 5 development(GO:0021571) |
| 0.1 | 2.2 | GO:0060396 | growth hormone receptor signaling pathway(GO:0060396) cellular response to growth hormone stimulus(GO:0071378) |
| 0.1 | 5.1 | GO:0032011 | ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012) |
| 0.1 | 2.5 | GO:0042993 | positive regulation of transcription factor import into nucleus(GO:0042993) |
| 0.1 | 1.0 | GO:0017185 | peptidyl-lysine hydroxylation(GO:0017185) |
| 0.1 | 0.5 | GO:0034499 | late endosome to Golgi transport(GO:0034499) |
| 0.1 | 1.5 | GO:0015074 | DNA integration(GO:0015074) |
| 0.1 | 4.6 | GO:0050710 | negative regulation of cytokine secretion(GO:0050710) |
| 0.1 | 0.8 | GO:1903361 | protein localization to basolateral plasma membrane(GO:1903361) |
| 0.1 | 0.5 | GO:1902683 | regulation of receptor localization to synapse(GO:1902683) |
| 0.1 | 0.5 | GO:0009298 | GDP-mannose biosynthetic process(GO:0009298) |
| 0.1 | 29.9 | GO:0000398 | RNA splicing, via transesterification reactions(GO:0000375) RNA splicing, via transesterification reactions with bulged adenosine as nucleophile(GO:0000377) mRNA splicing, via spliceosome(GO:0000398) |
| 0.1 | 0.6 | GO:0006421 | asparaginyl-tRNA aminoacylation(GO:0006421) |
| 0.1 | 0.8 | GO:0071883 | activation of MAPK activity by adrenergic receptor signaling pathway(GO:0071883) |
| 0.1 | 0.6 | GO:0010825 | positive regulation of centrosome duplication(GO:0010825) |
| 0.1 | 1.8 | GO:0035330 | regulation of hippo signaling(GO:0035330) |
| 0.1 | 0.8 | GO:0002829 | negative regulation of type 2 immune response(GO:0002829) |
| 0.1 | 5.4 | GO:2000008 | regulation of protein localization to cell surface(GO:2000008) |
| 0.1 | 9.8 | GO:2001237 | negative regulation of extrinsic apoptotic signaling pathway(GO:2001237) |
| 0.1 | 1.6 | GO:1900745 | positive regulation of p38MAPK cascade(GO:1900745) |
| 0.1 | 7.3 | GO:0071277 | cellular response to calcium ion(GO:0071277) |
| 0.1 | 6.8 | GO:0050766 | positive regulation of phagocytosis(GO:0050766) |
| 0.1 | 2.3 | GO:0042269 | regulation of natural killer cell mediated cytotoxicity(GO:0042269) |
| 0.1 | 4.3 | GO:0007616 | long-term memory(GO:0007616) |
| 0.1 | 3.4 | GO:0090162 | establishment of epithelial cell polarity(GO:0090162) |
| 0.1 | 1.8 | GO:0006336 | DNA replication-independent nucleosome assembly(GO:0006336) |
| 0.1 | 2.4 | GO:0046085 | adenosine metabolic process(GO:0046085) |
| 0.1 | 10.3 | GO:0007200 | phospholipase C-activating G-protein coupled receptor signaling pathway(GO:0007200) |
| 0.1 | 1.4 | GO:0002087 | regulation of respiratory gaseous exchange by neurological system process(GO:0002087) |
| 0.1 | 1.3 | GO:0031268 | pseudopodium organization(GO:0031268) |
| 0.1 | 4.3 | GO:0032642 | regulation of chemokine production(GO:0032642) |
| 0.1 | 4.1 | GO:2000036 | regulation of stem cell population maintenance(GO:2000036) |
| 0.1 | 0.3 | GO:2000584 | platelet-derived growth factor receptor-alpha signaling pathway(GO:0035790) regulation of platelet-derived growth factor receptor-alpha signaling pathway(GO:2000583) negative regulation of platelet-derived growth factor receptor-alpha signaling pathway(GO:2000584) |
| 0.1 | 1.2 | GO:0016180 | snRNA processing(GO:0016180) |
| 0.1 | 5.1 | GO:0006893 | Golgi to plasma membrane transport(GO:0006893) |
| 0.1 | 6.9 | GO:0043507 | positive regulation of JUN kinase activity(GO:0043507) |
| 0.1 | 1.7 | GO:0035855 | megakaryocyte development(GO:0035855) |
| 0.1 | 1.5 | GO:0032793 | positive regulation of CREB transcription factor activity(GO:0032793) |
| 0.1 | 0.4 | GO:0021691 | cerebellar Purkinje cell layer maturation(GO:0021691) |
| 0.1 | 3.3 | GO:0000060 | protein import into nucleus, translocation(GO:0000060) |
| 0.1 | 2.3 | GO:0002467 | germinal center formation(GO:0002467) |
| 0.1 | 3.0 | GO:0006541 | glutamine metabolic process(GO:0006541) |
| 0.1 | 0.6 | GO:0010592 | positive regulation of lamellipodium assembly(GO:0010592) |
| 0.1 | 0.8 | GO:0039536 | negative regulation of RIG-I signaling pathway(GO:0039536) |
| 0.1 | 2.3 | GO:0035116 | embryonic hindlimb morphogenesis(GO:0035116) |
| 0.1 | 4.6 | GO:0006367 | transcription initiation from RNA polymerase II promoter(GO:0006367) |
| 0.1 | 3.6 | GO:0045744 | negative regulation of G-protein coupled receptor protein signaling pathway(GO:0045744) |
| 0.1 | 1.2 | GO:0048642 | negative regulation of skeletal muscle tissue development(GO:0048642) |
| 0.1 | 2.1 | GO:0034508 | centromere complex assembly(GO:0034508) |
| 0.1 | 0.2 | GO:1900222 | negative regulation of beta-amyloid clearance(GO:1900222) |
| 0.1 | 2.8 | GO:0031424 | keratinization(GO:0031424) |
| 0.1 | 3.4 | GO:0006414 | translational elongation(GO:0006414) |
| 0.1 | 3.5 | GO:0050919 | negative chemotaxis(GO:0050919) |
| 0.1 | 1.8 | GO:0000184 | nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:0000184) |
| 0.1 | 0.7 | GO:0035372 | protein localization to microtubule(GO:0035372) |
| 0.1 | 0.6 | GO:0051683 | establishment of Golgi localization(GO:0051683) |
| 0.1 | 1.1 | GO:0006978 | DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:0006978) |
| 0.1 | 0.5 | GO:0042483 | negative regulation of odontogenesis(GO:0042483) |
| 0.1 | 0.8 | GO:0018026 | peptidyl-lysine monomethylation(GO:0018026) |
| 0.1 | 1.3 | GO:0045742 | positive regulation of epidermal growth factor receptor signaling pathway(GO:0045742) positive regulation of ERBB signaling pathway(GO:1901186) |
| 0.1 | 1.9 | GO:0097484 | dendrite extension(GO:0097484) |
| 0.1 | 1.5 | GO:0051457 | maintenance of protein location in nucleus(GO:0051457) |
| 0.1 | 5.7 | GO:0090630 | activation of GTPase activity(GO:0090630) |
| 0.1 | 0.1 | GO:0007406 | negative regulation of neuroblast proliferation(GO:0007406) |
| 0.1 | 0.3 | GO:0006049 | UDP-N-acetylglucosamine catabolic process(GO:0006049) nucleotide-sugar catabolic process(GO:0009227) |
| 0.1 | 1.9 | GO:2000279 | negative regulation of DNA biosynthetic process(GO:2000279) |
| 0.1 | 0.3 | GO:0045919 | positive regulation of cytolysis(GO:0045919) |
| 0.1 | 1.7 | GO:0002026 | regulation of the force of heart contraction(GO:0002026) |
| 0.1 | 0.8 | GO:0016540 | protein autoprocessing(GO:0016540) |
| 0.1 | 1.2 | GO:0044247 | glycogen catabolic process(GO:0005980) glucan catabolic process(GO:0009251) cellular polysaccharide catabolic process(GO:0044247) |
| 0.1 | 0.2 | GO:0060988 | lipid tube assembly(GO:0060988) |
| 0.1 | 0.5 | GO:0001867 | complement activation, lectin pathway(GO:0001867) |
| 0.1 | 3.7 | GO:0016525 | negative regulation of angiogenesis(GO:0016525) |
| 0.1 | 3.1 | GO:0050830 | defense response to Gram-positive bacterium(GO:0050830) |
| 0.1 | 1.5 | GO:0035019 | somatic stem cell population maintenance(GO:0035019) |
| 0.1 | 1.3 | GO:0070534 | protein K63-linked ubiquitination(GO:0070534) |
| 0.1 | 0.8 | GO:0010867 | positive regulation of triglyceride biosynthetic process(GO:0010867) |
| 0.1 | 0.4 | GO:2000346 | negative regulation of hepatocyte proliferation(GO:2000346) |
| 0.1 | 1.7 | GO:0016925 | protein sumoylation(GO:0016925) |
| 0.1 | 1.3 | GO:0035641 | locomotory exploration behavior(GO:0035641) |
| 0.1 | 0.3 | GO:0071360 | cellular response to exogenous dsRNA(GO:0071360) |
| 0.0 | 0.4 | GO:0033314 | mitotic DNA replication checkpoint(GO:0033314) |
| 0.0 | 0.6 | GO:0035024 | negative regulation of Rho protein signal transduction(GO:0035024) |
| 0.0 | 0.2 | GO:2000643 | positive regulation of early endosome to late endosome transport(GO:2000643) |
| 0.0 | 0.3 | GO:0035735 | intraciliary transport involved in cilium morphogenesis(GO:0035735) |
| 0.0 | 0.3 | GO:1902261 | positive regulation of delayed rectifier potassium channel activity(GO:1902261) |
| 0.0 | 0.1 | GO:0060011 | Sertoli cell proliferation(GO:0060011) |
| 0.0 | 0.5 | GO:0051694 | pointed-end actin filament capping(GO:0051694) |
| 0.0 | 0.8 | GO:0032728 | positive regulation of interferon-beta production(GO:0032728) |
| 0.0 | 1.2 | GO:0014003 | oligodendrocyte development(GO:0014003) |
| 0.0 | 0.3 | GO:0098719 | sodium ion import(GO:0097369) sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118) |
| 0.0 | 0.3 | GO:0070836 | plasma membrane raft assembly(GO:0044854) plasma membrane raft organization(GO:0044857) caveola assembly(GO:0070836) |
| 0.0 | 0.4 | GO:0061298 | retina vasculature development in camera-type eye(GO:0061298) |
| 0.0 | 0.1 | GO:0071596 | ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596) |
| 0.0 | 1.3 | GO:0030512 | negative regulation of transforming growth factor beta receptor signaling pathway(GO:0030512) negative regulation of cellular response to transforming growth factor beta stimulus(GO:1903845) |
| 0.0 | 0.4 | GO:0016973 | poly(A)+ mRNA export from nucleus(GO:0016973) |
| 0.0 | 0.3 | GO:1904153 | negative regulation of protein exit from endoplasmic reticulum(GO:0070862) negative regulation of retrograde protein transport, ER to cytosol(GO:1904153) |
| 0.0 | 0.5 | GO:0043551 | regulation of phosphatidylinositol 3-kinase activity(GO:0043551) |
| 0.0 | 0.5 | GO:0071353 | cellular response to interleukin-4(GO:0071353) |
| 0.0 | 0.1 | GO:0051771 | negative regulation of nitric-oxide synthase biosynthetic process(GO:0051771) |
| 0.0 | 0.1 | GO:0035112 | genitalia morphogenesis(GO:0035112) |
| 0.0 | 0.1 | GO:0010636 | positive regulation of mitochondrial fusion(GO:0010636) |
| 0.0 | 0.2 | GO:0030049 | muscle filament sliding(GO:0030049) |
| 0.0 | 0.3 | GO:0032516 | positive regulation of phosphoprotein phosphatase activity(GO:0032516) |
| 0.0 | 0.2 | GO:0000188 | inactivation of MAPK activity(GO:0000188) |
| 0.0 | 2.6 | GO:0035023 | regulation of Rho protein signal transduction(GO:0035023) |
| 0.0 | 0.1 | GO:0006432 | phenylalanyl-tRNA aminoacylation(GO:0006432) |
| 0.0 | 1.7 | GO:0007127 | meiosis I(GO:0007127) |
| 0.0 | 0.6 | GO:0043044 | ATP-dependent chromatin remodeling(GO:0043044) |
| 0.0 | 2.1 | GO:0006910 | phagocytosis, recognition(GO:0006910) |
| 0.0 | 0.6 | GO:0031146 | SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146) |
| 0.0 | 0.1 | GO:0044313 | protein K6-linked deubiquitination(GO:0044313) |
| 0.0 | 0.3 | GO:0051973 | positive regulation of telomerase activity(GO:0051973) |
| 0.0 | 0.5 | GO:0045807 | positive regulation of endocytosis(GO:0045807) |
| 0.0 | 0.4 | GO:0051567 | histone H3-K9 methylation(GO:0051567) |
| 0.0 | 0.2 | GO:0046855 | phosphorylated carbohydrate dephosphorylation(GO:0046838) inositol phosphate dephosphorylation(GO:0046855) |
| 0.0 | 0.2 | GO:0016486 | peptide hormone processing(GO:0016486) |
| 0.0 | 0.6 | GO:0000271 | polysaccharide biosynthetic process(GO:0000271) |
| 0.0 | 0.7 | GO:0031532 | actin cytoskeleton reorganization(GO:0031532) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 5.5 | 38.7 | GO:0097443 | sorting endosome(GO:0097443) |
| 4.2 | 12.7 | GO:0036398 | TCR signalosome(GO:0036398) |
| 4.2 | 20.8 | GO:0000799 | nuclear condensin complex(GO:0000799) |
| 4.1 | 12.3 | GO:1990031 | pinceau fiber(GO:1990031) |
| 3.6 | 10.7 | GO:0005656 | nuclear pre-replicative complex(GO:0005656) pre-replicative complex(GO:0036387) |
| 3.2 | 15.9 | GO:0034687 | integrin alphaL-beta2 complex(GO:0034687) |
| 3.1 | 51.9 | GO:0042582 | primary lysosome(GO:0005766) azurophil granule(GO:0042582) |
| 3.0 | 33.3 | GO:0097451 | glial limiting end-foot(GO:0097451) |
| 3.0 | 17.9 | GO:1990393 | 3M complex(GO:1990393) |
| 2.9 | 43.7 | GO:0043020 | NADPH oxidase complex(GO:0043020) |
| 2.7 | 8.1 | GO:0034455 | t-UTP complex(GO:0034455) |
| 2.7 | 10.7 | GO:0031680 | G-protein beta/gamma-subunit complex(GO:0031680) |
| 2.5 | 19.7 | GO:0035985 | senescence-associated heterochromatin focus(GO:0035985) |
| 2.4 | 7.2 | GO:0031904 | endosome lumen(GO:0031904) |
| 2.4 | 7.2 | GO:0005854 | nascent polypeptide-associated complex(GO:0005854) |
| 2.3 | 20.7 | GO:0071818 | BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379) |
| 2.3 | 18.0 | GO:0071204 | histone pre-mRNA 3'end processing complex(GO:0071204) |
| 2.2 | 22.3 | GO:0033093 | Weibel-Palade body(GO:0033093) |
| 2.1 | 8.5 | GO:0042585 | germinal vesicle(GO:0042585) |
| 2.0 | 14.3 | GO:0030289 | protein phosphatase 4 complex(GO:0030289) |
| 1.9 | 11.4 | GO:0005672 | transcription factor TFIIA complex(GO:0005672) |
| 1.8 | 22.0 | GO:0000801 | central element(GO:0000801) |
| 1.8 | 11.0 | GO:0005826 | actomyosin contractile ring(GO:0005826) |
| 1.8 | 5.4 | GO:0005607 | laminin-2 complex(GO:0005607) |
| 1.7 | 8.6 | GO:0005944 | phosphatidylinositol 3-kinase complex, class IB(GO:0005944) |
| 1.7 | 22.2 | GO:0005818 | aster(GO:0005818) |
| 1.6 | 9.8 | GO:0008537 | proteasome activator complex(GO:0008537) |
| 1.6 | 17.6 | GO:0005687 | U4 snRNP(GO:0005687) |
| 1.5 | 4.6 | GO:0070985 | TFIIK complex(GO:0070985) |
| 1.5 | 4.6 | GO:0042643 | actomyosin, actin portion(GO:0042643) |
| 1.5 | 10.7 | GO:0031429 | box H/ACA snoRNP complex(GO:0031429) box H/ACA RNP complex(GO:0072588) |
| 1.5 | 20.9 | GO:0031232 | extrinsic component of external side of plasma membrane(GO:0031232) |
| 1.4 | 22.9 | GO:0042555 | MCM complex(GO:0042555) |
| 1.4 | 7.1 | GO:0016602 | CCAAT-binding factor complex(GO:0016602) |
| 1.4 | 14.0 | GO:0019815 | B cell receptor complex(GO:0019815) |
| 1.4 | 23.4 | GO:0001931 | uropod(GO:0001931) cell trailing edge(GO:0031254) |
| 1.3 | 9.2 | GO:0005853 | eukaryotic translation elongation factor 1 complex(GO:0005853) |
| 1.3 | 16.6 | GO:0097136 | Bcl-2 family protein complex(GO:0097136) |
| 1.2 | 4.9 | GO:0071011 | precatalytic spliceosome(GO:0071011) |
| 1.2 | 6.1 | GO:0030690 | Noc1p-Noc2p complex(GO:0030690) |
| 1.2 | 84.9 | GO:0000307 | cyclin-dependent protein kinase holoenzyme complex(GO:0000307) |
| 1.2 | 4.8 | GO:0008275 | gamma-tubulin small complex(GO:0008275) |
| 1.2 | 8.3 | GO:0005658 | alpha DNA polymerase:primase complex(GO:0005658) |
| 1.2 | 8.1 | GO:0031095 | platelet dense tubular network membrane(GO:0031095) |
| 1.1 | 92.7 | GO:0022625 | cytosolic large ribosomal subunit(GO:0022625) |
| 1.1 | 6.7 | GO:0033553 | rDNA heterochromatin(GO:0033553) |
| 1.1 | 7.8 | GO:0042406 | extrinsic component of endoplasmic reticulum membrane(GO:0042406) |
| 1.1 | 3.3 | GO:0030905 | retromer, tubulation complex(GO:0030905) |
| 1.0 | 3.1 | GO:0071007 | U2-type catalytic step 2 spliceosome(GO:0071007) |
| 1.0 | 5.2 | GO:0031298 | replication fork protection complex(GO:0031298) |
| 1.0 | 10.3 | GO:0042382 | paraspeckles(GO:0042382) |
| 1.0 | 7.1 | GO:0036194 | muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195) |
| 1.0 | 8.1 | GO:0005662 | DNA replication factor A complex(GO:0005662) |
| 1.0 | 57.1 | GO:0022627 | cytosolic small ribosomal subunit(GO:0022627) |
| 0.9 | 1.9 | GO:0098592 | cytoplasmic side of apical plasma membrane(GO:0098592) |
| 0.9 | 7.9 | GO:0071141 | SMAD protein complex(GO:0071141) |
| 0.9 | 2.6 | GO:0000110 | nucleotide-excision repair factor 1 complex(GO:0000110) |
| 0.8 | 11.1 | GO:0000974 | Prp19 complex(GO:0000974) |
| 0.8 | 7.0 | GO:0000808 | origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664) |
| 0.8 | 10.5 | GO:0005736 | DNA-directed RNA polymerase I complex(GO:0005736) |
| 0.7 | 41.1 | GO:0001772 | immunological synapse(GO:0001772) |
| 0.7 | 9.4 | GO:0005688 | U6 snRNP(GO:0005688) |
| 0.7 | 4.8 | GO:0036396 | MIS complex(GO:0036396) |
| 0.7 | 2.1 | GO:0031074 | nucleocytoplasmic shuttling complex(GO:0031074) |
| 0.7 | 6.8 | GO:0061574 | ASAP complex(GO:0061574) |
| 0.7 | 14.6 | GO:0014731 | spectrin-associated cytoskeleton(GO:0014731) |
| 0.7 | 9.2 | GO:0005686 | U2 snRNP(GO:0005686) |
| 0.7 | 11.7 | GO:0005852 | eukaryotic translation initiation factor 3 complex(GO:0005852) |
| 0.6 | 14.3 | GO:0031616 | spindle pole centrosome(GO:0031616) |
| 0.6 | 52.1 | GO:0030118 | clathrin coat(GO:0030118) |
| 0.6 | 5.1 | GO:0005828 | kinetochore microtubule(GO:0005828) |
| 0.6 | 20.8 | GO:0005721 | pericentric heterochromatin(GO:0005721) |
| 0.6 | 3.8 | GO:0042583 | chromaffin granule(GO:0042583) |
| 0.6 | 6.9 | GO:0031080 | nuclear pore outer ring(GO:0031080) |
| 0.6 | 13.1 | GO:0002199 | zona pellucida receptor complex(GO:0002199) |
| 0.6 | 3.7 | GO:0034709 | methylosome(GO:0034709) |
| 0.6 | 2.4 | GO:0044393 | microspike(GO:0044393) |
| 0.6 | 4.2 | GO:0034388 | Pwp2p-containing subcomplex of 90S preribosome(GO:0034388) |
| 0.6 | 7.1 | GO:0008278 | cohesin complex(GO:0008278) |
| 0.6 | 8.7 | GO:0005862 | muscle thin filament tropomyosin(GO:0005862) |
| 0.6 | 4.5 | GO:0044615 | nuclear pore nuclear basket(GO:0044615) |
| 0.6 | 6.2 | GO:0031258 | lamellipodium membrane(GO:0031258) |
| 0.6 | 3.3 | GO:0005682 | U5 snRNP(GO:0005682) |
| 0.5 | 2.7 | GO:0000120 | RNA polymerase I transcription factor complex(GO:0000120) |
| 0.5 | 22.5 | GO:0035371 | microtubule plus-end(GO:0035371) |
| 0.5 | 14.3 | GO:0001891 | phagocytic cup(GO:0001891) |
| 0.5 | 2.1 | GO:0008623 | CHRAC(GO:0008623) |
| 0.5 | 2.1 | GO:0031092 | platelet alpha granule membrane(GO:0031092) |
| 0.5 | 2.6 | GO:0010370 | perinucleolar chromocenter(GO:0010370) |
| 0.5 | 3.1 | GO:1903439 | calcitonin family receptor complex(GO:1903439) amylin receptor complex(GO:1903440) |
| 0.5 | 7.8 | GO:0005689 | U12-type spliceosomal complex(GO:0005689) |
| 0.5 | 13.2 | GO:0031362 | anchored component of external side of plasma membrane(GO:0031362) |
| 0.5 | 68.1 | GO:0017053 | transcriptional repressor complex(GO:0017053) |
| 0.5 | 5.2 | GO:0097197 | tetraspanin-enriched microdomain(GO:0097197) |
| 0.5 | 4.7 | GO:0071437 | invadopodium(GO:0071437) |
| 0.5 | 4.6 | GO:0031390 | Ctf18 RFC-like complex(GO:0031390) |
| 0.5 | 10.0 | GO:0031527 | filopodium membrane(GO:0031527) |
| 0.5 | 1.4 | GO:0031372 | UBC13-MMS2 complex(GO:0031372) |
| 0.4 | 19.1 | GO:0097228 | sperm principal piece(GO:0097228) |
| 0.4 | 7.8 | GO:0036038 | MKS complex(GO:0036038) |
| 0.4 | 17.9 | GO:0008305 | integrin complex(GO:0008305) |
| 0.4 | 4.9 | GO:0071004 | U2-type prespliceosome(GO:0071004) |
| 0.4 | 39.5 | GO:0071013 | catalytic step 2 spliceosome(GO:0071013) |
| 0.4 | 1.2 | GO:0034657 | GID complex(GO:0034657) |
| 0.4 | 6.3 | GO:0030119 | AP-type membrane coat adaptor complex(GO:0030119) |
| 0.4 | 1.5 | GO:0097543 | ciliary inversin compartment(GO:0097543) |
| 0.4 | 2.2 | GO:0097550 | transcriptional preinitiation complex(GO:0097550) |
| 0.4 | 4.0 | GO:0042105 | alpha-beta T cell receptor complex(GO:0042105) |
| 0.3 | 1.4 | GO:0036019 | endolysosome(GO:0036019) |
| 0.3 | 1.7 | GO:0031510 | SUMO activating enzyme complex(GO:0031510) |
| 0.3 | 4.4 | GO:0030688 | preribosome, small subunit precursor(GO:0030688) |
| 0.3 | 1.3 | GO:0033596 | TSC1-TSC2 complex(GO:0033596) |
| 0.3 | 13.2 | GO:0071339 | MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339) |
| 0.3 | 10.2 | GO:0033017 | sarcoplasmic reticulum membrane(GO:0033017) |
| 0.3 | 4.2 | GO:0030670 | phagocytic vesicle membrane(GO:0030670) |
| 0.3 | 8.8 | GO:0031588 | nucleotide-activated protein kinase complex(GO:0031588) |
| 0.3 | 33.1 | GO:0030864 | cortical actin cytoskeleton(GO:0030864) |
| 0.3 | 0.6 | GO:0035068 | micro-ribonucleoprotein complex(GO:0035068) |
| 0.3 | 0.9 | GO:0048179 | activin receptor complex(GO:0048179) |
| 0.3 | 2.4 | GO:0097422 | tubular endosome(GO:0097422) |
| 0.3 | 0.9 | GO:0071001 | U4/U6 snRNP(GO:0071001) |
| 0.3 | 3.6 | GO:0005742 | mitochondrial outer membrane translocase complex(GO:0005742) |
| 0.3 | 3.0 | GO:0030915 | Smc5-Smc6 complex(GO:0030915) |
| 0.3 | 8.3 | GO:0030687 | preribosome, large subunit precursor(GO:0030687) |
| 0.3 | 11.5 | GO:0002102 | podosome(GO:0002102) |
| 0.3 | 3.7 | GO:0031932 | TORC2 complex(GO:0031932) |
| 0.3 | 1.1 | GO:0032021 | NELF complex(GO:0032021) |
| 0.3 | 3.9 | GO:0000813 | ESCRT I complex(GO:0000813) |
| 0.3 | 2.7 | GO:0000127 | transcription factor TFIIIC complex(GO:0000127) |
| 0.3 | 0.8 | GO:0071595 | Nem1-Spo7 phosphatase complex(GO:0071595) |
| 0.3 | 3.8 | GO:0005640 | nuclear outer membrane(GO:0005640) |
| 0.3 | 18.2 | GO:0005834 | heterotrimeric G-protein complex(GO:0005834) |
| 0.3 | 2.6 | GO:0044754 | secondary lysosome(GO:0005767) autolysosome(GO:0044754) |
| 0.3 | 4.0 | GO:0032580 | Golgi cisterna membrane(GO:0032580) |
| 0.3 | 0.8 | GO:0036501 | UFD1-NPL4 complex(GO:0036501) |
| 0.2 | 1.2 | GO:0000938 | GARP complex(GO:0000938) EARP complex(GO:1990745) |
| 0.2 | 7.5 | GO:0005680 | anaphase-promoting complex(GO:0005680) |
| 0.2 | 16.5 | GO:0005871 | kinesin complex(GO:0005871) |
| 0.2 | 1.8 | GO:0070847 | core mediator complex(GO:0070847) |
| 0.2 | 0.7 | GO:0000125 | PCAF complex(GO:0000125) |
| 0.2 | 2.0 | GO:0034719 | SMN-Sm protein complex(GO:0034719) |
| 0.2 | 1.4 | GO:0072357 | PTW/PP1 phosphatase complex(GO:0072357) |
| 0.2 | 3.7 | GO:0000346 | transcription export complex(GO:0000346) |
| 0.2 | 0.9 | GO:0005850 | eukaryotic translation initiation factor 2 complex(GO:0005850) |
| 0.2 | 37.2 | GO:0001650 | fibrillar center(GO:0001650) |
| 0.2 | 1.1 | GO:0030314 | junctional membrane complex(GO:0030314) |
| 0.2 | 2.3 | GO:0016272 | prefoldin complex(GO:0016272) |
| 0.2 | 2.9 | GO:0030126 | COPI vesicle coat(GO:0030126) |
| 0.2 | 1.8 | GO:0070775 | H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776) |
| 0.2 | 9.3 | GO:0030863 | cortical cytoskeleton(GO:0030863) |
| 0.2 | 2.1 | GO:0042587 | glycogen granule(GO:0042587) |
| 0.2 | 4.3 | GO:0012507 | ER to Golgi transport vesicle membrane(GO:0012507) |
| 0.2 | 2.0 | GO:0000788 | nuclear nucleosome(GO:0000788) |
| 0.2 | 1.1 | GO:0032777 | Piccolo NuA4 histone acetyltransferase complex(GO:0032777) |
| 0.2 | 1.8 | GO:0044300 | cerebellar mossy fiber(GO:0044300) |
| 0.2 | 7.0 | GO:0055038 | recycling endosome membrane(GO:0055038) |
| 0.2 | 1.2 | GO:0044611 | nuclear pore inner ring(GO:0044611) |
| 0.2 | 1.8 | GO:0031371 | ubiquitin conjugating enzyme complex(GO:0031371) |
| 0.2 | 1.2 | GO:0005851 | eukaryotic translation initiation factor 2B complex(GO:0005851) |
| 0.2 | 4.1 | GO:0008074 | guanylate cyclase complex, soluble(GO:0008074) |
| 0.2 | 2.7 | GO:0035145 | exon-exon junction complex(GO:0035145) |
| 0.1 | 2.4 | GO:0031414 | N-terminal protein acetyltransferase complex(GO:0031414) |
| 0.1 | 4.9 | GO:0015030 | Cajal body(GO:0015030) |
| 0.1 | 2.0 | GO:0031209 | SCAR complex(GO:0031209) |
| 0.1 | 1.4 | GO:0000242 | pericentriolar material(GO:0000242) |
| 0.1 | 2.2 | GO:0035327 | transcriptionally active chromatin(GO:0035327) |
| 0.1 | 3.4 | GO:0030014 | CCR4-NOT complex(GO:0030014) |
| 0.1 | 0.9 | GO:1990909 | Wnt signalosome(GO:1990909) |
| 0.1 | 1.8 | GO:0005666 | DNA-directed RNA polymerase III complex(GO:0005666) |
| 0.1 | 6.0 | GO:0005905 | clathrin-coated pit(GO:0005905) |
| 0.1 | 4.4 | GO:0045335 | phagocytic vesicle(GO:0045335) |
| 0.1 | 2.3 | GO:0005861 | troponin complex(GO:0005861) |
| 0.1 | 2.1 | GO:0000506 | glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506) |
| 0.1 | 1.3 | GO:0005796 | Golgi lumen(GO:0005796) |
| 0.1 | 1.4 | GO:0042613 | MHC class II protein complex(GO:0042613) |
| 0.1 | 2.0 | GO:0097539 | ciliary transition fiber(GO:0097539) |
| 0.1 | 1.3 | GO:0016600 | flotillin complex(GO:0016600) |
| 0.1 | 0.4 | GO:0090498 | extrinsic component of Golgi membrane(GO:0090498) |
| 0.1 | 3.2 | GO:0051233 | spindle midzone(GO:0051233) |
| 0.1 | 4.6 | GO:0016459 | myosin complex(GO:0016459) |
| 0.1 | 1.1 | GO:0005885 | Arp2/3 protein complex(GO:0005885) |
| 0.1 | 6.4 | GO:0031672 | A band(GO:0031672) |
| 0.1 | 2.2 | GO:0032588 | trans-Golgi network membrane(GO:0032588) |
| 0.1 | 2.2 | GO:0065010 | extracellular membrane-bounded organelle(GO:0065010) |
| 0.1 | 9.2 | GO:0097517 | stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517) |
| 0.1 | 55.2 | GO:0031012 | extracellular matrix(GO:0031012) |
| 0.1 | 1.2 | GO:0044452 | nucleolar part(GO:0044452) |
| 0.1 | 23.5 | GO:0031965 | nuclear membrane(GO:0031965) |
| 0.1 | 0.4 | GO:0031314 | extrinsic component of mitochondrial inner membrane(GO:0031314) |
| 0.1 | 1.3 | GO:0031143 | pseudopodium(GO:0031143) |
| 0.1 | 2.2 | GO:0042588 | zymogen granule(GO:0042588) |
| 0.1 | 0.9 | GO:0043219 | lateral loop(GO:0043219) |
| 0.1 | 1.4 | GO:0030686 | 90S preribosome(GO:0030686) |
| 0.1 | 3.7 | GO:0005657 | replication fork(GO:0005657) |
| 0.1 | 3.9 | GO:0044295 | axonal growth cone(GO:0044295) |
| 0.1 | 0.7 | GO:0005744 | mitochondrial inner membrane presequence translocase complex(GO:0005744) |
| 0.1 | 1.3 | GO:0016442 | RISC complex(GO:0016442) RNAi effector complex(GO:0031332) |
| 0.1 | 0.4 | GO:0030914 | STAGA complex(GO:0030914) |
| 0.1 | 2.2 | GO:0016327 | apicolateral plasma membrane(GO:0016327) |
| 0.1 | 2.0 | GO:0043196 | varicosity(GO:0043196) |
| 0.1 | 1.0 | GO:0033276 | transcription factor TFTC complex(GO:0033276) |
| 0.1 | 3.1 | GO:0030673 | axolemma(GO:0030673) |
| 0.1 | 1.0 | GO:0017101 | aminoacyl-tRNA synthetase multienzyme complex(GO:0017101) |
| 0.1 | 0.4 | GO:0070876 | SOSS complex(GO:0070876) |
| 0.1 | 0.6 | GO:0005671 | Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671) |
| 0.1 | 4.2 | GO:0005681 | spliceosomal complex(GO:0005681) |
| 0.1 | 11.4 | GO:0001726 | ruffle(GO:0001726) |
| 0.1 | 1.2 | GO:0097038 | perinuclear endoplasmic reticulum(GO:0097038) |
| 0.1 | 2.1 | GO:0080008 | Cul4-RING E3 ubiquitin ligase complex(GO:0080008) |
| 0.1 | 0.1 | GO:0034673 | inhibin-betaglycan-ActRII complex(GO:0034673) |
| 0.1 | 1.1 | GO:0005847 | mRNA cleavage and polyadenylation specificity factor complex(GO:0005847) |
| 0.1 | 0.4 | GO:1990111 | spermatoproteasome complex(GO:1990111) |
| 0.1 | 5.3 | GO:0016605 | PML body(GO:0016605) |
| 0.1 | 0.5 | GO:0005697 | telomerase holoenzyme complex(GO:0005697) |
| 0.1 | 0.7 | GO:0032039 | integrator complex(GO:0032039) |
| 0.1 | 4.1 | GO:0005884 | actin filament(GO:0005884) |
| 0.1 | 0.2 | GO:0048237 | rough endoplasmic reticulum lumen(GO:0048237) |
| 0.1 | 0.6 | GO:0005869 | dynactin complex(GO:0005869) |
| 0.1 | 1.4 | GO:0035861 | site of double-strand break(GO:0035861) |
| 0.1 | 1.5 | GO:0005719 | nuclear euchromatin(GO:0005719) |
| 0.1 | 1.1 | GO:0030140 | trans-Golgi network transport vesicle(GO:0030140) |
| 0.1 | 5.8 | GO:0030027 | lamellipodium(GO:0030027) |
| 0.1 | 0.3 | GO:0034448 | EGO complex(GO:0034448) Gtr1-Gtr2 GTPase complex(GO:1990131) |
| 0.0 | 3.7 | GO:0019005 | SCF ubiquitin ligase complex(GO:0019005) |
| 0.0 | 0.6 | GO:0033256 | I-kappaB/NF-kappaB complex(GO:0033256) |
| 0.0 | 3.5 | GO:0031234 | extrinsic component of cytoplasmic side of plasma membrane(GO:0031234) |
| 0.0 | 9.5 | GO:0000793 | condensed chromosome(GO:0000793) |
| 0.0 | 0.3 | GO:0032593 | insulin-responsive compartment(GO:0032593) |
| 0.0 | 0.4 | GO:0005845 | mRNA cap binding complex(GO:0005845) RNA cap binding complex(GO:0034518) |
| 0.0 | 1.4 | GO:0016235 | aggresome(GO:0016235) |
| 0.0 | 0.4 | GO:0005786 | signal recognition particle, endoplasmic reticulum targeting(GO:0005786) |
| 0.0 | 0.8 | GO:0097610 | cleavage furrow(GO:0032154) cell surface furrow(GO:0097610) |
| 0.0 | 0.7 | GO:0000145 | exocyst(GO:0000145) |
| 0.0 | 3.2 | GO:0030018 | Z disc(GO:0030018) |
| 0.0 | 0.1 | GO:0009328 | phenylalanine-tRNA ligase complex(GO:0009328) |
| 0.0 | 2.0 | GO:0001750 | photoreceptor outer segment(GO:0001750) |
| 0.0 | 0.4 | GO:0090543 | Flemming body(GO:0090543) |
| 0.0 | 0.6 | GO:0005771 | multivesicular body(GO:0005771) |
| 0.0 | 4.7 | GO:0043197 | dendritic spine(GO:0043197) |
| 0.0 | 0.5 | GO:0042622 | photoreceptor outer segment membrane(GO:0042622) |
| 0.0 | 0.6 | GO:0031901 | early endosome membrane(GO:0031901) |
| 0.0 | 1.8 | GO:0005814 | centriole(GO:0005814) |
| 0.0 | 2.1 | GO:0019814 | immunoglobulin complex(GO:0019814) |
| 0.0 | 1.4 | GO:0043195 | terminal bouton(GO:0043195) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 4.2 | 33.7 | GO:0035662 | Toll-like receptor 4 binding(GO:0035662) |
| 3.4 | 13.8 | GO:0015057 | thrombin receptor activity(GO:0015057) |
| 3.2 | 15.9 | GO:0030369 | ICAM-3 receptor activity(GO:0030369) |
| 3.0 | 39.2 | GO:0016176 | superoxide-generating NADPH oxidase activator activity(GO:0016176) |
| 2.9 | 11.4 | GO:1990932 | 5.8S rRNA binding(GO:1990932) |
| 2.8 | 8.3 | GO:0070138 | isopeptidase activity(GO:0070122) ubiquitin-like protein-specific isopeptidase activity(GO:0070138) SUMO-specific isopeptidase activity(GO:0070140) |
| 2.7 | 13.7 | GO:0070051 | fibrinogen binding(GO:0070051) |
| 2.6 | 7.9 | GO:0035500 | MH2 domain binding(GO:0035500) |
| 2.6 | 15.7 | GO:0061575 | cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575) |
| 2.6 | 12.8 | GO:0042610 | CD8 receptor binding(GO:0042610) |
| 2.5 | 15.1 | GO:0017077 | oxidative phosphorylation uncoupler activity(GO:0017077) |
| 2.5 | 9.9 | GO:0071207 | histone pre-mRNA stem-loop binding(GO:0071207) |
| 2.5 | 7.4 | GO:0044715 | 8-oxo-dGDP phosphatase activity(GO:0044715) |
| 2.4 | 21.7 | GO:0061676 | importin-alpha family protein binding(GO:0061676) |
| 2.4 | 12.0 | GO:0030621 | U4 snRNA binding(GO:0030621) |
| 2.3 | 6.8 | GO:0001132 | RNA polymerase II transcription factor activity, TBP-class protein binding, involved in preinitiation complex assembly(GO:0001129) RNA polymerase II transcription factor activity, TBP-class protein binding(GO:0001132) |
| 2.2 | 19.7 | GO:0051575 | 5'-deoxyribose-5-phosphate lyase activity(GO:0051575) |
| 2.1 | 10.6 | GO:0004345 | glucose-6-phosphate dehydrogenase activity(GO:0004345) |
| 2.0 | 8.1 | GO:0071208 | histone pre-mRNA DCP binding(GO:0071208) |
| 2.0 | 12.0 | GO:0046624 | sphingolipid transporter activity(GO:0046624) |
| 2.0 | 9.8 | GO:0004974 | leukotriene receptor activity(GO:0004974) |
| 1.9 | 7.8 | GO:0043532 | angiostatin binding(GO:0043532) |
| 1.9 | 5.7 | GO:0097100 | supercoiled DNA binding(GO:0097100) |
| 1.8 | 5.4 | GO:0001042 | RNA polymerase I core binding(GO:0001042) |
| 1.8 | 19.5 | GO:0033691 | sialic acid binding(GO:0033691) |
| 1.7 | 6.6 | GO:0052743 | inositol tetrakisphosphate phosphatase activity(GO:0052743) |
| 1.6 | 19.7 | GO:0003886 | DNA (cytosine-5-)-methyltransferase activity(GO:0003886) |
| 1.6 | 7.8 | GO:0010997 | anaphase-promoting complex binding(GO:0010997) |
| 1.5 | 10.7 | GO:0034513 | box H/ACA snoRNA binding(GO:0034513) |
| 1.5 | 6.0 | GO:0032422 | purine-rich negative regulatory element binding(GO:0032422) |
| 1.4 | 12.7 | GO:0016286 | small conductance calcium-activated potassium channel activity(GO:0016286) |
| 1.4 | 9.6 | GO:0047179 | platelet-activating factor acetyltransferase activity(GO:0047179) |
| 1.4 | 13.6 | GO:0051434 | BH3 domain binding(GO:0051434) |
| 1.3 | 4.0 | GO:0003896 | DNA primase activity(GO:0003896) |
| 1.3 | 9.3 | GO:0004704 | NF-kappaB-inducing kinase activity(GO:0004704) |
| 1.3 | 4.0 | GO:0004821 | histidine-tRNA ligase activity(GO:0004821) |
| 1.3 | 3.9 | GO:0051916 | granulocyte colony-stimulating factor binding(GO:0051916) |
| 1.3 | 3.8 | GO:0030943 | mitochondrion targeting sequence binding(GO:0030943) |
| 1.3 | 7.6 | GO:0001165 | RNA polymerase I upstream control element sequence-specific DNA binding(GO:0001165) |
| 1.3 | 3.8 | GO:0009383 | rRNA (cytosine-C5-)-methyltransferase activity(GO:0009383) |
| 1.2 | 71.1 | GO:0004693 | cyclin-dependent protein serine/threonine kinase activity(GO:0004693) |
| 1.2 | 9.6 | GO:0004726 | non-membrane spanning protein tyrosine phosphatase activity(GO:0004726) |
| 1.2 | 3.6 | GO:0019948 | SUMO activating enzyme activity(GO:0019948) |
| 1.2 | 3.5 | GO:0003999 | adenine binding(GO:0002055) adenine phosphoribosyltransferase activity(GO:0003999) |
| 1.2 | 11.7 | GO:0008093 | cytoskeletal adaptor activity(GO:0008093) |
| 1.2 | 3.5 | GO:0098808 | mRNA cap binding(GO:0098808) |
| 1.1 | 24.0 | GO:0035612 | AP-2 adaptor complex binding(GO:0035612) |
| 1.1 | 4.6 | GO:0004694 | eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694) |
| 1.1 | 11.3 | GO:0030235 | nitric-oxide synthase regulator activity(GO:0030235) |
| 1.1 | 19.0 | GO:0005522 | profilin binding(GO:0005522) |
| 1.1 | 8.9 | GO:0031493 | nucleosomal histone binding(GO:0031493) |
| 1.1 | 47.8 | GO:0043325 | phosphatidylinositol-3,4-bisphosphate binding(GO:0043325) |
| 1.1 | 8.8 | GO:0004679 | AMP-activated protein kinase activity(GO:0004679) |
| 1.1 | 4.4 | GO:0051435 | BH4 domain binding(GO:0051435) |
| 1.1 | 3.2 | GO:0001096 | TFIIF-class transcription factor binding(GO:0001096) |
| 1.1 | 13.9 | GO:0001055 | RNA polymerase II activity(GO:0001055) |
| 1.1 | 10.7 | GO:0004064 | arylesterase activity(GO:0004064) |
| 1.0 | 7.2 | GO:0016312 | inositol bisphosphate phosphatase activity(GO:0016312) |
| 1.0 | 3.1 | GO:0070401 | NADP+ binding(GO:0070401) |
| 1.0 | 20.3 | GO:0015643 | toxic substance binding(GO:0015643) |
| 1.0 | 4.1 | GO:0004335 | galactokinase activity(GO:0004335) |
| 1.0 | 10.1 | GO:0050733 | RS domain binding(GO:0050733) |
| 1.0 | 7.8 | GO:0042609 | CD4 receptor binding(GO:0042609) |
| 1.0 | 12.6 | GO:0071933 | Arp2/3 complex binding(GO:0071933) |
| 1.0 | 7.6 | GO:0004687 | myosin light chain kinase activity(GO:0004687) |
| 1.0 | 2.9 | GO:0008192 | RNA guanylyltransferase activity(GO:0008192) |
| 0.9 | 7.5 | GO:0008865 | fructokinase activity(GO:0008865) mannokinase activity(GO:0019158) |
| 0.9 | 3.7 | GO:0050347 | trans-hexaprenyltranstransferase activity(GO:0000010) trans-octaprenyltranstransferase activity(GO:0050347) |
| 0.9 | 2.7 | GO:0050510 | N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510) |
| 0.9 | 2.7 | GO:0005157 | macrophage colony-stimulating factor receptor binding(GO:0005157) |
| 0.9 | 6.2 | GO:0016428 | tRNA (cytosine-5-)-methyltransferase activity(GO:0016428) |
| 0.9 | 13.9 | GO:0043138 | 3'-5' DNA helicase activity(GO:0043138) |
| 0.9 | 9.4 | GO:0070990 | snRNP binding(GO:0070990) |
| 0.9 | 11.1 | GO:0019957 | C-C chemokine binding(GO:0019957) |
| 0.8 | 5.9 | GO:0032027 | myosin light chain binding(GO:0032027) |
| 0.8 | 20.7 | GO:0008179 | adenylate cyclase binding(GO:0008179) |
| 0.8 | 3.3 | GO:1990460 | leptin receptor binding(GO:1990460) |
| 0.8 | 12.1 | GO:0008097 | 5S rRNA binding(GO:0008097) |
| 0.8 | 3.2 | GO:0097001 | interleukin-4 receptor binding(GO:0005136) ceramide binding(GO:0097001) |
| 0.8 | 4.7 | GO:0004966 | galanin receptor activity(GO:0004966) |
| 0.8 | 2.4 | GO:0001156 | TFIIIC-class transcription factor binding(GO:0001156) |
| 0.8 | 8.6 | GO:0061133 | endopeptidase activator activity(GO:0061133) |
| 0.8 | 3.1 | GO:0004699 | calcium-independent protein kinase C activity(GO:0004699) TIR domain binding(GO:0070976) |
| 0.8 | 9.4 | GO:0035368 | selenocysteine insertion sequence binding(GO:0035368) |
| 0.8 | 3.1 | GO:0000822 | inositol hexakisphosphate binding(GO:0000822) |
| 0.8 | 5.4 | GO:0043208 | glycosphingolipid binding(GO:0043208) |
| 0.8 | 3.9 | GO:0003917 | DNA topoisomerase type I activity(GO:0003917) |
| 0.8 | 12.0 | GO:0008349 | MAP kinase kinase kinase kinase activity(GO:0008349) |
| 0.7 | 17.2 | GO:0031681 | G-protein beta-subunit binding(GO:0031681) |
| 0.7 | 3.0 | GO:0003883 | CTP synthase activity(GO:0003883) |
| 0.7 | 5.9 | GO:0050786 | RAGE receptor binding(GO:0050786) |
| 0.7 | 9.8 | GO:0035925 | mRNA 3'-UTR AU-rich region binding(GO:0035925) |
| 0.7 | 22.3 | GO:0004190 | aspartic-type endopeptidase activity(GO:0004190) |
| 0.7 | 6.8 | GO:0003810 | protein-glutamine gamma-glutamyltransferase activity(GO:0003810) |
| 0.7 | 19.5 | GO:0004003 | ATP-dependent DNA helicase activity(GO:0004003) |
| 0.7 | 6.0 | GO:0003836 | beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836) |
| 0.7 | 7.3 | GO:0050700 | CARD domain binding(GO:0050700) |
| 0.7 | 23.1 | GO:0017025 | TBP-class protein binding(GO:0017025) |
| 0.7 | 5.9 | GO:0070181 | small ribosomal subunit rRNA binding(GO:0070181) |
| 0.7 | 8.5 | GO:0046934 | phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol bisphosphate kinase activity(GO:0052813) |
| 0.7 | 2.6 | GO:0047389 | glycerophosphocholine phosphodiesterase activity(GO:0047389) |
| 0.6 | 32.5 | GO:0001106 | RNA polymerase II transcription corepressor activity(GO:0001106) |
| 0.6 | 15.8 | GO:0004435 | phosphatidylinositol phospholipase C activity(GO:0004435) |
| 0.6 | 2.5 | GO:0004830 | tryptophan-tRNA ligase activity(GO:0004830) |
| 0.6 | 3.0 | GO:0004809 | tRNA (guanine-N2-)-methyltransferase activity(GO:0004809) |
| 0.6 | 1.8 | GO:0001147 | transcription termination site sequence-specific DNA binding(GO:0001147) transcription termination site DNA binding(GO:0001160) |
| 0.6 | 2.9 | GO:0070180 | large ribosomal subunit rRNA binding(GO:0070180) |
| 0.6 | 13.4 | GO:0019865 | immunoglobulin binding(GO:0019865) |
| 0.6 | 4.7 | GO:0070290 | N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290) |
| 0.6 | 6.3 | GO:0004908 | interleukin-1 receptor activity(GO:0004908) |
| 0.6 | 5.1 | GO:1990825 | sequence-specific mRNA binding(GO:1990825) |
| 0.6 | 1.7 | GO:0018169 | ribosomal S6-glutamic acid ligase activity(GO:0018169) |
| 0.6 | 2.2 | GO:0004949 | cannabinoid receptor activity(GO:0004949) |
| 0.5 | 3.8 | GO:0019808 | polyamine binding(GO:0019808) |
| 0.5 | 7.1 | GO:0019198 | transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198) |
| 0.5 | 2.7 | GO:0043812 | phosphatidylinositol-4-phosphate phosphatase activity(GO:0043812) |
| 0.5 | 14.0 | GO:0017091 | AU-rich element binding(GO:0017091) |
| 0.5 | 2.1 | GO:0004105 | choline-phosphate cytidylyltransferase activity(GO:0004105) |
| 0.5 | 7.8 | GO:0051525 | NFAT protein binding(GO:0051525) |
| 0.5 | 3.1 | GO:0097643 | amylin receptor activity(GO:0097643) |
| 0.5 | 7.1 | GO:0030274 | LIM domain binding(GO:0030274) |
| 0.5 | 4.0 | GO:0030229 | very-low-density lipoprotein particle receptor activity(GO:0030229) |
| 0.5 | 36.2 | GO:0050840 | extracellular matrix binding(GO:0050840) |
| 0.5 | 8.5 | GO:0035174 | histone serine kinase activity(GO:0035174) |
| 0.5 | 12.3 | GO:0004033 | aldo-keto reductase (NADP) activity(GO:0004033) |
| 0.5 | 2.4 | GO:0098809 | nitrite reductase activity(GO:0098809) |
| 0.5 | 5.8 | GO:0051400 | BH domain binding(GO:0051400) |
| 0.5 | 7.1 | GO:0050897 | cobalt ion binding(GO:0050897) |
| 0.5 | 2.8 | GO:0089720 | caspase binding(GO:0089720) |
| 0.5 | 4.6 | GO:0008527 | taste receptor activity(GO:0008527) |
| 0.5 | 5.0 | GO:0003689 | DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170) |
| 0.5 | 4.5 | GO:0016175 | superoxide-generating NADPH oxidase activity(GO:0016175) |
| 0.4 | 3.1 | GO:0017070 | U6 snRNA binding(GO:0017070) |
| 0.4 | 31.5 | GO:0004601 | peroxidase activity(GO:0004601) |
| 0.4 | 4.4 | GO:0016531 | copper chaperone activity(GO:0016531) |
| 0.4 | 5.6 | GO:0005049 | nuclear export signal receptor activity(GO:0005049) |
| 0.4 | 75.5 | GO:0003735 | structural constituent of ribosome(GO:0003735) |
| 0.4 | 2.6 | GO:0045322 | unmethylated CpG binding(GO:0045322) |
| 0.4 | 6.0 | GO:0042731 | PH domain binding(GO:0042731) |
| 0.4 | 18.4 | GO:0043027 | cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027) |
| 0.4 | 5.0 | GO:0030628 | pre-mRNA 3'-splice site binding(GO:0030628) |
| 0.4 | 3.2 | GO:0001849 | complement component C1q binding(GO:0001849) |
| 0.4 | 19.7 | GO:0001965 | G-protein alpha-subunit binding(GO:0001965) |
| 0.4 | 2.8 | GO:0010859 | calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859) |
| 0.4 | 1.2 | GO:0004134 | glycogen debranching enzyme activity(GO:0004133) 4-alpha-glucanotransferase activity(GO:0004134) amylo-alpha-1,6-glucosidase activity(GO:0004135) |
| 0.4 | 2.8 | GO:0043515 | kinetochore binding(GO:0043515) |
| 0.4 | 26.2 | GO:0004004 | RNA helicase activity(GO:0003724) ATP-dependent RNA helicase activity(GO:0004004) ATP-dependent helicase activity(GO:0008026) RNA-dependent ATPase activity(GO:0008186) purine NTP-dependent helicase activity(GO:0070035) |
| 0.4 | 1.9 | GO:0019976 | interleukin-2 binding(GO:0019976) |
| 0.4 | 1.9 | GO:0061649 | ubiquitinated histone binding(GO:0061649) |
| 0.4 | 22.4 | GO:0015175 | neutral amino acid transmembrane transporter activity(GO:0015175) |
| 0.4 | 1.9 | GO:0030911 | TPR domain binding(GO:0030911) |
| 0.4 | 5.2 | GO:0098505 | G-rich strand telomeric DNA binding(GO:0098505) |
| 0.4 | 4.8 | GO:0050815 | phosphoserine binding(GO:0050815) |
| 0.4 | 16.2 | GO:0005547 | phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547) |
| 0.4 | 3.3 | GO:0015266 | protein channel activity(GO:0015266) |
| 0.4 | 1.8 | GO:0010484 | H3 histone acetyltransferase activity(GO:0010484) |
| 0.4 | 1.8 | GO:0000700 | mismatch base pair DNA N-glycosylase activity(GO:0000700) |
| 0.3 | 1.4 | GO:0044729 | hemi-methylated DNA-binding(GO:0044729) |
| 0.3 | 4.1 | GO:0004016 | adenylate cyclase activity(GO:0004016) |
| 0.3 | 3.4 | GO:0001163 | RNA polymerase I regulatory region sequence-specific DNA binding(GO:0001163) RNA polymerase I CORE element sequence-specific DNA binding(GO:0001164) |
| 0.3 | 2.0 | GO:0001099 | basal transcription machinery binding(GO:0001098) basal RNA polymerase II transcription machinery binding(GO:0001099) |
| 0.3 | 5.8 | GO:0001727 | lipid kinase activity(GO:0001727) |
| 0.3 | 12.2 | GO:0044183 | protein binding involved in protein folding(GO:0044183) |
| 0.3 | 6.0 | GO:0070182 | DNA polymerase binding(GO:0070182) |
| 0.3 | 1.0 | GO:0034618 | arginine binding(GO:0034618) |
| 0.3 | 7.3 | GO:0043274 | phospholipase binding(GO:0043274) |
| 0.3 | 132.8 | GO:0030695 | GTPase regulator activity(GO:0030695) |
| 0.3 | 3.3 | GO:0017049 | GTP-Rho binding(GO:0017049) |
| 0.3 | 3.4 | GO:0000774 | adenyl-nucleotide exchange factor activity(GO:0000774) |
| 0.3 | 2.2 | GO:0004782 | sulfinoalanine decarboxylase activity(GO:0004782) |
| 0.3 | 0.6 | GO:0031871 | proteinase activated receptor binding(GO:0031871) |
| 0.3 | 0.9 | GO:0000995 | transcription factor activity, core RNA polymerase III binding(GO:0000995) |
| 0.3 | 9.1 | GO:0051879 | Hsp90 protein binding(GO:0051879) |
| 0.3 | 6.6 | GO:0004653 | polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653) |
| 0.3 | 6.0 | GO:0051011 | microtubule minus-end binding(GO:0051011) |
| 0.3 | 4.8 | GO:0009982 | pseudouridine synthase activity(GO:0009982) |
| 0.3 | 1.8 | GO:0019961 | interferon binding(GO:0019961) |
| 0.3 | 8.7 | GO:0000993 | RNA polymerase II core binding(GO:0000993) |
| 0.3 | 4.7 | GO:0017017 | MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017) |
| 0.3 | 1.1 | GO:0051377 | mannose-ethanolamine phosphotransferase activity(GO:0051377) |
| 0.3 | 4.2 | GO:0001618 | virus receptor activity(GO:0001618) |
| 0.3 | 6.7 | GO:0070063 | RNA polymerase binding(GO:0070063) |
| 0.3 | 1.3 | GO:0042134 | rRNA primary transcript binding(GO:0042134) |
| 0.3 | 1.6 | GO:1990430 | extracellular matrix protein binding(GO:1990430) |
| 0.3 | 3.1 | GO:0051861 | glycolipid binding(GO:0051861) |
| 0.3 | 1.3 | GO:0005021 | vascular endothelial growth factor-activated receptor activity(GO:0005021) |
| 0.3 | 7.8 | GO:0005112 | Notch binding(GO:0005112) |
| 0.3 | 3.5 | GO:0031432 | titin binding(GO:0031432) |
| 0.3 | 17.1 | GO:0001205 | transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205) |
| 0.2 | 4.5 | GO:0005078 | MAP-kinase scaffold activity(GO:0005078) |
| 0.2 | 11.8 | GO:0003755 | peptidyl-prolyl cis-trans isomerase activity(GO:0003755) |
| 0.2 | 3.7 | GO:0008327 | methyl-CpG binding(GO:0008327) |
| 0.2 | 5.6 | GO:0019843 | rRNA binding(GO:0019843) |
| 0.2 | 0.7 | GO:0000033 | alpha-1,3-mannosyltransferase activity(GO:0000033) |
| 0.2 | 15.7 | GO:0003743 | translation initiation factor activity(GO:0003743) |
| 0.2 | 1.9 | GO:0008823 | cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851) |
| 0.2 | 1.6 | GO:0008559 | xenobiotic-transporting ATPase activity(GO:0008559) |
| 0.2 | 2.1 | GO:0005068 | transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068) |
| 0.2 | 7.8 | GO:0030676 | Rac guanyl-nucleotide exchange factor activity(GO:0030676) |
| 0.2 | 2.3 | GO:0031014 | troponin T binding(GO:0031014) |
| 0.2 | 0.9 | GO:0033906 | hyaluronoglucuronidase activity(GO:0033906) |
| 0.2 | 12.2 | GO:0030544 | Hsp70 protein binding(GO:0030544) |
| 0.2 | 1.4 | GO:0044020 | protein-arginine omega-N monomethyltransferase activity(GO:0035241) histone methyltransferase activity (H4-R3 specific)(GO:0044020) |
| 0.2 | 3.7 | GO:0023026 | MHC class II protein complex binding(GO:0023026) |
| 0.2 | 5.5 | GO:0030515 | snoRNA binding(GO:0030515) |
| 0.2 | 1.5 | GO:0015288 | porin activity(GO:0015288) |
| 0.2 | 8.4 | GO:0043548 | phosphatidylinositol 3-kinase binding(GO:0043548) |
| 0.2 | 1.7 | GO:0032051 | clathrin light chain binding(GO:0032051) |
| 0.2 | 6.9 | GO:0004709 | MAP kinase kinase kinase activity(GO:0004709) |
| 0.2 | 9.4 | GO:0004869 | cysteine-type endopeptidase inhibitor activity(GO:0004869) |
| 0.2 | 2.1 | GO:1901612 | cardiolipin binding(GO:1901612) |
| 0.2 | 0.9 | GO:0016422 | mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity(GO:0016422) |
| 0.2 | 9.8 | GO:0003785 | actin monomer binding(GO:0003785) |
| 0.2 | 2.8 | GO:0008417 | fucosyltransferase activity(GO:0008417) |
| 0.2 | 5.0 | GO:0003841 | 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841) |
| 0.2 | 2.9 | GO:0032036 | myosin heavy chain binding(GO:0032036) |
| 0.2 | 4.9 | GO:0003746 | translation elongation factor activity(GO:0003746) |
| 0.2 | 10.0 | GO:0005070 | SH3/SH2 adaptor activity(GO:0005070) |
| 0.2 | 8.4 | GO:0042169 | SH2 domain binding(GO:0042169) |
| 0.2 | 0.8 | GO:0030984 | kininogen binding(GO:0030984) |
| 0.2 | 10.8 | GO:0001105 | RNA polymerase II transcription coactivator activity(GO:0001105) |
| 0.2 | 1.2 | GO:0070815 | peptidyl-lysine 5-dioxygenase activity(GO:0070815) |
| 0.2 | 1.1 | GO:0036310 | annealing helicase activity(GO:0036310) |
| 0.2 | 4.8 | GO:0046966 | thyroid hormone receptor binding(GO:0046966) |
| 0.2 | 6.6 | GO:1990841 | promoter-specific chromatin binding(GO:1990841) |
| 0.2 | 3.7 | GO:0005545 | 1-phosphatidylinositol binding(GO:0005545) |
| 0.2 | 0.7 | GO:0004127 | cytidylate kinase activity(GO:0004127) |
| 0.2 | 0.6 | GO:0004912 | interleukin-3 receptor activity(GO:0004912) interleukin-3 binding(GO:0019978) |
| 0.2 | 37.8 | GO:0042393 | histone binding(GO:0042393) |
| 0.2 | 0.5 | GO:0005087 | Ran guanyl-nucleotide exchange factor activity(GO:0005087) |
| 0.2 | 17.8 | GO:0008565 | protein transporter activity(GO:0008565) |
| 0.2 | 0.5 | GO:0004615 | phosphomannomutase activity(GO:0004615) |
| 0.2 | 2.5 | GO:0042577 | lipid phosphatase activity(GO:0042577) |
| 0.2 | 7.1 | GO:0043015 | gamma-tubulin binding(GO:0043015) |
| 0.2 | 8.0 | GO:0005044 | scavenger receptor activity(GO:0005044) |
| 0.2 | 5.1 | GO:0008569 | ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569) |
| 0.2 | 0.6 | GO:0004816 | asparagine-tRNA ligase activity(GO:0004816) |
| 0.2 | 14.3 | GO:0005089 | Rho guanyl-nucleotide exchange factor activity(GO:0005089) |
| 0.2 | 9.5 | GO:0008307 | structural constituent of muscle(GO:0008307) |
| 0.2 | 2.2 | GO:0015197 | peptide transporter activity(GO:0015197) |
| 0.2 | 0.5 | GO:0004829 | threonine-tRNA ligase activity(GO:0004829) |
| 0.2 | 5.1 | GO:0005086 | ARF guanyl-nucleotide exchange factor activity(GO:0005086) |
| 0.2 | 1.5 | GO:0003958 | NADPH-hemoprotein reductase activity(GO:0003958) |
| 0.2 | 2.1 | GO:0017176 | phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176) |
| 0.1 | 1.9 | GO:0004697 | protein kinase C activity(GO:0004697) |
| 0.1 | 2.4 | GO:0004550 | nucleoside diphosphate kinase activity(GO:0004550) |
| 0.1 | 0.6 | GO:0000340 | RNA 7-methylguanosine cap binding(GO:0000340) |
| 0.1 | 5.2 | GO:0071949 | FAD binding(GO:0071949) |
| 0.1 | 2.0 | GO:0016755 | transferase activity, transferring amino-acyl groups(GO:0016755) |
| 0.1 | 0.9 | GO:0016361 | activin receptor activity, type I(GO:0016361) |
| 0.1 | 2.1 | GO:0098811 | transcriptional activator activity, RNA polymerase II transcription factor binding(GO:0001190) transcriptional repressor activity, RNA polymerase II activating transcription factor binding(GO:0098811) |
| 0.1 | 1.8 | GO:0001968 | fibronectin binding(GO:0001968) |
| 0.1 | 1.8 | GO:0001056 | RNA polymerase III activity(GO:0001056) |
| 0.1 | 0.1 | GO:0017002 | activin-activated receptor activity(GO:0017002) |
| 0.1 | 3.7 | GO:0004181 | metallocarboxypeptidase activity(GO:0004181) |
| 0.1 | 0.7 | GO:0019958 | C-X-C chemokine binding(GO:0019958) |
| 0.1 | 0.5 | GO:0046935 | 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935) |
| 0.1 | 1.6 | GO:0070628 | proteasome binding(GO:0070628) |
| 0.1 | 3.8 | GO:0043395 | heparan sulfate proteoglycan binding(GO:0043395) |
| 0.1 | 0.4 | GO:0046964 | 3'-phosphoadenosine 5'-phosphosulfate transmembrane transporter activity(GO:0046964) |
| 0.1 | 0.6 | GO:0070012 | oligopeptidase activity(GO:0070012) |
| 0.1 | 0.5 | GO:0004609 | phosphatidylserine decarboxylase activity(GO:0004609) |
| 0.1 | 25.0 | GO:0003714 | transcription corepressor activity(GO:0003714) |
| 0.1 | 0.4 | GO:0098918 | structural constituent of synapse(GO:0098918) structural constituent of postsynaptic actin cytoskeleton(GO:0098973) |
| 0.1 | 1.6 | GO:0003899 | DNA-directed RNA polymerase activity(GO:0003899) |
| 0.1 | 6.0 | GO:0005504 | fatty acid binding(GO:0005504) |
| 0.1 | 0.9 | GO:0008821 | crossover junction endodeoxyribonuclease activity(GO:0008821) |
| 0.1 | 0.8 | GO:0070569 | uridylyltransferase activity(GO:0070569) |
| 0.1 | 0.9 | GO:0030306 | ADP-ribosylation factor binding(GO:0030306) |
| 0.1 | 1.6 | GO:0017127 | cholesterol transporter activity(GO:0017127) |
| 0.1 | 0.3 | GO:0003923 | GPI-anchor transamidase activity(GO:0003923) |
| 0.1 | 2.7 | GO:0017128 | phospholipid scramblase activity(GO:0017128) |
| 0.1 | 1.5 | GO:0042162 | telomeric DNA binding(GO:0042162) |
| 0.1 | 0.8 | GO:0008440 | inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440) |
| 0.1 | 2.5 | GO:0005544 | calcium-dependent phospholipid binding(GO:0005544) |
| 0.1 | 3.5 | GO:0001221 | transcription cofactor binding(GO:0001221) |
| 0.1 | 0.7 | GO:0032050 | clathrin heavy chain binding(GO:0032050) |
| 0.1 | 0.8 | GO:0004311 | farnesyltranstransferase activity(GO:0004311) |
| 0.1 | 0.4 | GO:0097003 | adipokinetic hormone receptor activity(GO:0097003) |
| 0.1 | 2.0 | GO:0031492 | nucleosomal DNA binding(GO:0031492) |
| 0.1 | 13.6 | GO:0008201 | heparin binding(GO:0008201) |
| 0.1 | 0.8 | GO:0030368 | interleukin-17 receptor activity(GO:0030368) |
| 0.1 | 0.8 | GO:0008603 | cAMP-dependent protein kinase regulator activity(GO:0008603) |
| 0.1 | 1.0 | GO:0005338 | nucleotide-sugar transmembrane transporter activity(GO:0005338) |
| 0.1 | 3.4 | GO:0005546 | phosphatidylinositol-4,5-bisphosphate binding(GO:0005546) |
| 0.1 | 3.9 | GO:0050699 | WW domain binding(GO:0050699) |
| 0.1 | 0.9 | GO:0034236 | protein kinase A catalytic subunit binding(GO:0034236) |
| 0.1 | 10.1 | GO:0004867 | serine-type endopeptidase inhibitor activity(GO:0004867) |
| 0.1 | 5.7 | GO:0004527 | exonuclease activity(GO:0004527) |
| 0.1 | 0.3 | GO:0097199 | death effector domain binding(GO:0035877) cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097199) |
| 0.1 | 2.1 | GO:0003887 | DNA-directed DNA polymerase activity(GO:0003887) |
| 0.1 | 1.5 | GO:0034237 | protein kinase A regulatory subunit binding(GO:0034237) |
| 0.1 | 3.8 | GO:0005518 | collagen binding(GO:0005518) |
| 0.1 | 0.7 | GO:0071253 | connexin binding(GO:0071253) |
| 0.1 | 1.2 | GO:0005487 | nucleocytoplasmic transporter activity(GO:0005487) |
| 0.1 | 1.9 | GO:0003950 | NAD+ ADP-ribosyltransferase activity(GO:0003950) |
| 0.1 | 0.3 | GO:0003827 | alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827) |
| 0.1 | 0.4 | GO:0030942 | endoplasmic reticulum signal peptide binding(GO:0030942) |
| 0.1 | 0.5 | GO:0015129 | lactate transmembrane transporter activity(GO:0015129) |
| 0.1 | 0.7 | GO:0017134 | fibroblast growth factor binding(GO:0017134) |
| 0.1 | 0.4 | GO:0008318 | protein prenyltransferase activity(GO:0008318) |
| 0.1 | 0.6 | GO:0008242 | omega peptidase activity(GO:0008242) |
| 0.0 | 0.5 | GO:0008432 | JUN kinase binding(GO:0008432) |
| 0.0 | 1.2 | GO:0008253 | 5'-nucleotidase activity(GO:0008253) |
| 0.0 | 2.0 | GO:0030507 | spectrin binding(GO:0030507) |
| 0.0 | 1.0 | GO:0008574 | ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574) |
| 0.0 | 26.3 | GO:0003779 | actin binding(GO:0003779) |
| 0.0 | 1.1 | GO:0031489 | myosin V binding(GO:0031489) |
| 0.0 | 0.8 | GO:0017160 | Ral GTPase binding(GO:0017160) |
| 0.0 | 2.4 | GO:0004714 | transmembrane receptor protein tyrosine kinase activity(GO:0004714) |
| 0.0 | 1.4 | GO:0005031 | tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035) |
| 0.0 | 1.7 | GO:0005385 | zinc ion transmembrane transporter activity(GO:0005385) |
| 0.0 | 3.4 | GO:0008276 | protein methyltransferase activity(GO:0008276) |
| 0.0 | 3.1 | GO:0004540 | ribonuclease activity(GO:0004540) |
| 0.0 | 1.1 | GO:0043539 | protein serine/threonine kinase activator activity(GO:0043539) |
| 0.0 | 1.2 | GO:0001786 | phosphatidylserine binding(GO:0001786) |
| 0.0 | 0.2 | GO:0000900 | translation repressor activity, nucleic acid binding(GO:0000900) |
| 0.0 | 0.9 | GO:0004012 | phospholipid-translocating ATPase activity(GO:0004012) |
| 0.0 | 0.1 | GO:0043139 | 5'-3' DNA helicase activity(GO:0043139) |
| 0.0 | 0.7 | GO:0005388 | calcium-transporting ATPase activity(GO:0005388) |
| 0.0 | 1.8 | GO:0003730 | mRNA 3'-UTR binding(GO:0003730) |
| 0.0 | 0.1 | GO:0036033 | mediator complex binding(GO:0036033) |
| 0.0 | 0.1 | GO:0070728 | leucine binding(GO:0070728) |
| 0.0 | 2.2 | GO:0047485 | protein N-terminus binding(GO:0047485) |
| 0.0 | 0.1 | GO:0034452 | dynactin binding(GO:0034452) |
| 0.0 | 0.9 | GO:0008235 | metalloexopeptidase activity(GO:0008235) |
| 0.0 | 0.2 | GO:0015386 | potassium:proton antiporter activity(GO:0015386) |
| 0.0 | 0.1 | GO:0004826 | phenylalanine-tRNA ligase activity(GO:0004826) |
| 0.0 | 2.1 | GO:0034987 | immunoglobulin receptor binding(GO:0034987) |
| 0.0 | 2.0 | GO:0000149 | SNARE binding(GO:0000149) |
| 0.0 | 0.2 | GO:0070300 | phosphatidic acid binding(GO:0070300) |
| 0.0 | 0.2 | GO:0030742 | GTP-dependent protein binding(GO:0030742) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.7 | 39.8 | PID THROMBIN PAR4 PATHWAY | PAR4-mediated thrombin signaling events |
| 1.5 | 23.9 | SA MMP CYTOKINE CONNECTION | Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix. |
| 1.2 | 7.3 | SA G2 AND M PHASES | Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition. |
| 1.1 | 19.3 | PID TCR JNK PATHWAY | JNK signaling in the CD4+ TCR pathway |
| 1.1 | 50.6 | PID IL23 PATHWAY | IL23-mediated signaling events |
| 1.0 | 74.0 | PID IL2 STAT5 PATHWAY | IL2 signaling events mediated by STAT5 |
| 1.0 | 50.4 | PID AURORA A PATHWAY | Aurora A signaling |
| 0.9 | 13.2 | PID TCR RAS PATHWAY | Ras signaling in the CD4+ TCR pathway |
| 0.9 | 33.8 | PID INTEGRIN CS PATHWAY | Integrin family cell surface interactions |
| 0.9 | 46.3 | PID ATR PATHWAY | ATR signaling pathway |
| 0.8 | 41.7 | PID BCR 5PATHWAY | BCR signaling pathway |
| 0.8 | 35.1 | PID AURORA B PATHWAY | Aurora B signaling |
| 0.7 | 12.5 | PID LYMPH ANGIOGENESIS PATHWAY | VEGFR3 signaling in lymphatic endothelium |
| 0.7 | 65.4 | PID RAC1 REG PATHWAY | Regulation of RAC1 activity |
| 0.7 | 50.4 | PID IL4 2PATHWAY | IL4-mediated signaling events |
| 0.6 | 20.1 | PID UPA UPAR PATHWAY | Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling |
| 0.6 | 44.6 | PID RAC1 PATHWAY | RAC1 signaling pathway |
| 0.6 | 13.3 | PID INTEGRIN2 PATHWAY | Beta2 integrin cell surface interactions |
| 0.6 | 19.2 | PID TOLL ENDOGENOUS PATHWAY | Endogenous TLR signaling |
| 0.6 | 19.2 | PID FOXM1 PATHWAY | FOXM1 transcription factor network |
| 0.6 | 9.6 | SA REG CASCADE OF CYCLIN EXPR | Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases. |
| 0.6 | 30.6 | PID FAK PATHWAY | Signaling events mediated by focal adhesion kinase |
| 0.5 | 5.2 | PID ECADHERIN KERATINOCYTE PATHWAY | E-cadherin signaling in keratinocytes |
| 0.5 | 10.8 | PID INTEGRIN A9B1 PATHWAY | Alpha9 beta1 integrin signaling events |
| 0.5 | 12.7 | PID MYC PATHWAY | C-MYC pathway |
| 0.4 | 5.4 | PID INTEGRIN4 PATHWAY | Alpha6 beta4 integrin-ligand interactions |
| 0.4 | 10.1 | PID ECADHERIN NASCENT AJ PATHWAY | E-cadherin signaling in the nascent adherens junction |
| 0.4 | 10.1 | PID SYNDECAN 2 PATHWAY | Syndecan-2-mediated signaling events |
| 0.4 | 21.7 | SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES | Genes related to the insulin receptor pathway |
| 0.4 | 25.8 | PID RB 1PATHWAY | Regulation of retinoblastoma protein |
| 0.4 | 17.0 | PID ILK PATHWAY | Integrin-linked kinase signaling |
| 0.3 | 6.2 | PID ARF 3PATHWAY | Arf1 pathway |
| 0.3 | 8.6 | PID EPHA FWDPATHWAY | EPHA forward signaling |
| 0.3 | 11.2 | PID TAP63 PATHWAY | Validated transcriptional targets of TAp63 isoforms |
| 0.3 | 49.3 | PID P53 DOWNSTREAM PATHWAY | Direct p53 effectors |
| 0.3 | 3.3 | PID ARF6 DOWNSTREAM PATHWAY | Arf6 downstream pathway |
| 0.3 | 4.1 | PID IL2 PI3K PATHWAY | IL2 signaling events mediated by PI3K |
| 0.3 | 9.7 | PID LIS1 PATHWAY | Lissencephaly gene (LIS1) in neuronal migration and development |
| 0.3 | 15.1 | PID HNF3B PATHWAY | FOXA2 and FOXA3 transcription factor networks |
| 0.3 | 12.2 | PID TCR PATHWAY | TCR signaling in naïve CD4+ T cells |
| 0.3 | 9.6 | PID FCER1 PATHWAY | Fc-epsilon receptor I signaling in mast cells |
| 0.2 | 1.4 | SA PTEN PATHWAY | PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate. |
| 0.2 | 3.6 | PID SMAD2 3PATHWAY | Regulation of cytoplasmic and nuclear SMAD2/3 signaling |
| 0.2 | 19.7 | PID CMYB PATHWAY | C-MYB transcription factor network |
| 0.2 | 3.8 | PID CIRCADIAN PATHWAY | Circadian rhythm pathway |
| 0.2 | 6.9 | ST WNT BETA CATENIN PATHWAY | Wnt/beta-catenin Pathway |
| 0.2 | 4.1 | PID LPA4 PATHWAY | LPA4-mediated signaling events |
| 0.2 | 19.4 | PID AR PATHWAY | Coregulation of Androgen receptor activity |
| 0.2 | 1.7 | PID ERB GENOMIC PATHWAY | Validated nuclear estrogen receptor beta network |
| 0.2 | 10.9 | PID SMAD2 3NUCLEAR PATHWAY | Regulation of nuclear SMAD2/3 signaling |
| 0.2 | 5.9 | PID ARF6 TRAFFICKING PATHWAY | Arf6 trafficking events |
| 0.2 | 2.7 | PID EPHB FWD PATHWAY | EPHB forward signaling |
| 0.2 | 6.5 | PID AJDISS 2PATHWAY | Posttranslational regulation of adherens junction stability and dissassembly |
| 0.1 | 27.8 | NABA ECM AFFILIATED | Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins |
| 0.1 | 5.6 | PID P53 REGULATION PATHWAY | p53 pathway |
| 0.1 | 3.0 | PID IL1 PATHWAY | IL1-mediated signaling events |
| 0.1 | 30.8 | NABA ECM REGULATORS | Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix |
| 0.1 | 3.4 | PID FANCONI PATHWAY | Fanconi anemia pathway |
| 0.1 | 3.0 | PID PI3KCI PATHWAY | Class I PI3K signaling events |
| 0.1 | 2.0 | PID PI3K PLC TRK PATHWAY | Trk receptor signaling mediated by PI3K and PLC-gamma |
| 0.1 | 1.9 | PID MET PATHWAY | Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met) |
| 0.1 | 1.8 | PID ERBB NETWORK PATHWAY | ErbB receptor signaling network |
| 0.1 | 2.5 | ST GA13 PATHWAY | G alpha 13 Pathway |
| 0.1 | 2.7 | PID KIT PATHWAY | Signaling events mediated by Stem cell factor receptor (c-Kit) |
| 0.1 | 2.4 | PID VEGFR1 2 PATHWAY | Signaling events mediated by VEGFR1 and VEGFR2 |
| 0.1 | 0.5 | PID VEGF VEGFR PATHWAY | VEGF and VEGFR signaling network |
| 0.1 | 3.1 | PID TELOMERASE PATHWAY | Regulation of Telomerase |
| 0.1 | 1.3 | PID P38 ALPHA BETA PATHWAY | Regulation of p38-alpha and p38-beta |
| 0.1 | 0.7 | PID CXCR3 PATHWAY | CXCR3-mediated signaling events |
| 0.1 | 0.9 | PID ALK2 PATHWAY | ALK2 signaling events |
| 0.1 | 0.8 | PID IL27 PATHWAY | IL27-mediated signaling events |
| 0.1 | 0.6 | PID RET PATHWAY | Signaling events regulated by Ret tyrosine kinase |
| 0.1 | 0.9 | PID BETA CATENIN DEG PATHWAY | Degradation of beta catenin |
| 0.1 | 0.8 | PID P38 GAMMA DELTA PATHWAY | Signaling mediated by p38-gamma and p38-delta |
| 0.1 | 2.3 | SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES | Genes related to regulation of the actin cytoskeleton |
| 0.1 | 0.3 | PID EPHRINB REV PATHWAY | Ephrin B reverse signaling |
| 0.1 | 1.4 | PID HIF2PATHWAY | HIF-2-alpha transcription factor network |
| 0.1 | 0.7 | PID IL6 7 PATHWAY | IL6-mediated signaling events |
| 0.1 | 1.0 | PID P38 MKK3 6PATHWAY | p38 MAPK signaling pathway |
| 0.0 | 9.4 | NABA ECM GLYCOPROTEINS | Genes encoding structural ECM glycoproteins |
| 0.0 | 0.6 | PID IL3 PATHWAY | IL3-mediated signaling events |
| 0.0 | 0.1 | PID ALK1 PATHWAY | ALK1 signaling events |
| 0.0 | 1.3 | PID ERA GENOMIC PATHWAY | Validated nuclear estrogen receptor alpha network |
| 0.0 | 0.3 | PID THROMBIN PAR1 PATHWAY | PAR1-mediated thrombin signaling events |
| 0.0 | 0.3 | PID MTOR 4PATHWAY | mTOR signaling pathway |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 3.0 | 21.3 | REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION | Genes involved in APOBEC3G mediated resistance to HIV-1 infection |
| 2.6 | 41.0 | REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN | Genes involved in Platelet Adhesion to exposed collagen |
| 1.9 | 30.9 | REACTOME UNWINDING OF DNA | Genes involved in Unwinding of DNA |
| 1.9 | 24.5 | REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS | Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs |
| 1.7 | 32.4 | REACTOME GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTERGRINS | Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins |
| 1.6 | 26.7 | REACTOME CD28 DEPENDENT VAV1 PATHWAY | Genes involved in CD28 dependent Vav1 pathway |
| 1.6 | 98.6 | REACTOME G1 PHASE | Genes involved in G1 Phase |
| 1.4 | 8.3 | REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1 | Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1 |
| 1.2 | 18.6 | REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION | Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression |
| 1.2 | 145.4 | REACTOME PEPTIDE CHAIN ELONGATION | Genes involved in Peptide chain elongation |
| 1.1 | 25.3 | REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS | Genes involved in Signal regulatory protein (SIRP) family interactions |
| 1.0 | 12.7 | REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND | Genes involved in Removal of the Flap Intermediate from the C-strand |
| 0.9 | 10.0 | REACTOME GENERATION OF SECOND MESSENGER MOLECULES | Genes involved in Generation of second messenger molecules |
| 0.9 | 26.6 | REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX | Genes involved in Degradation of the extracellular matrix |
| 0.8 | 19.5 | REACTOME INFLAMMASOMES | Genes involved in Inflammasomes |
| 0.8 | 39.3 | REACTOME GPVI MEDIATED ACTIVATION CASCADE | Genes involved in GPVI-mediated activation cascade |
| 0.8 | 35.5 | REACTOME SIGNALING BY ROBO RECEPTOR | Genes involved in Signaling by Robo receptor |
| 0.8 | 9.9 | REACTOME RNA POL I PROMOTER OPENING | Genes involved in RNA Polymerase I Promoter Opening |
| 0.8 | 4.7 | REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS | Genes involved in Phosphorylation of CD3 and TCR zeta chains |
| 0.8 | 25.0 | REACTOME ELONGATION ARREST AND RECOVERY | Genes involved in Elongation arrest and recovery |
| 0.8 | 16.4 | REACTOME PROCESSING OF INTRONLESS PRE MRNAS | Genes involved in Processing of Intronless Pre-mRNAs |
| 0.8 | 37.9 | REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS | Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis |
| 0.7 | 4.4 | REACTOME FORMATION OF TRANSCRIPTION COUPLED NER TC NER REPAIR COMPLEX | Genes involved in Formation of transcription-coupled NER (TC-NER) repair complex |
| 0.7 | 10.2 | REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK | Genes involved in Regulation of Rheb GTPase activity by AMPK |
| 0.7 | 16.0 | REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE | Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere |
| 0.7 | 28.7 | REACTOME G PROTEIN BETA GAMMA SIGNALLING | Genes involved in G-protein beta:gamma signalling |
| 0.7 | 7.0 | REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX | Genes involved in CDC6 association with the ORC:origin complex |
| 0.7 | 19.2 | REACTOME MRNA 3 END PROCESSING | Genes involved in mRNA 3'-end processing |
| 0.7 | 8.5 | REACTOME COMMON PATHWAY | Genes involved in Common Pathway |
| 0.6 | 5.2 | REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA | Genes involved in Activation of Chaperone Genes by ATF6-alpha |
| 0.6 | 13.8 | REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS | Genes involved in Thrombin signalling through proteinase activated receptors (PARs) |
| 0.6 | 26.8 | REACTOME BASIGIN INTERACTIONS | Genes involved in Basigin interactions |
| 0.6 | 13.3 | REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS | Genes involved in Termination of O-glycan biosynthesis |
| 0.5 | 6.6 | REACTOME RAF MAP KINASE CASCADE | Genes involved in RAF/MAP kinase cascade |
| 0.5 | 10.3 | REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC | Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC |
| 0.5 | 9.2 | REACTOME MRNA SPLICING MINOR PATHWAY | Genes involved in mRNA Splicing - Minor Pathway |
| 0.5 | 10.2 | REACTOME PRE NOTCH PROCESSING IN GOLGI | Genes involved in Pre-NOTCH Processing in Golgi |
| 0.5 | 9.1 | REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE | Genes involved in mRNA Decay by 5' to 3' Exoribonuclease |
| 0.5 | 7.5 | REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES | Genes involved in Recruitment of NuMA to mitotic centrosomes |
| 0.5 | 13.6 | REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC | Genes involved in Formation of tubulin folding intermediates by CCT/TriC |
| 0.4 | 5.4 | REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR | Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor |
| 0.4 | 14.0 | REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION | Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription |
| 0.4 | 19.9 | REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE | Genes involved in Amino acid transport across the plasma membrane |
| 0.4 | 7.1 | REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX | Genes involved in Formation of the ternary complex, and subsequently, the 43S complex |
| 0.4 | 30.1 | REACTOME MRNA SPLICING | Genes involved in mRNA Splicing |
| 0.4 | 16.3 | REACTOME RECYCLING PATHWAY OF L1 | Genes involved in Recycling pathway of L1 |
| 0.4 | 20.4 | REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL | Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell |
| 0.4 | 2.6 | REACTOME PACKAGING OF TELOMERE ENDS | Genes involved in Packaging Of Telomere Ends |
| 0.4 | 2.5 | REACTOME ADP SIGNALLING THROUGH P2RY1 | Genes involved in ADP signalling through P2Y purinoceptor 1 |
| 0.4 | 3.9 | REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS | Genes involved in Membrane binding and targetting of GAG proteins |
| 0.3 | 11.5 | REACTOME RAP1 SIGNALLING | Genes involved in Rap1 signalling |
| 0.3 | 1.4 | REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING | Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling |
| 0.3 | 2.7 | REACTOME RNA POL I TRANSCRIPTION TERMINATION | Genes involved in RNA Polymerase I Transcription Termination |
| 0.3 | 8.9 | REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING | Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening |
| 0.3 | 10.1 | REACTOME SYNTHESIS OF PC | Genes involved in Synthesis of PC |
| 0.3 | 17.3 | REACTOME GLUCOSE TRANSPORT | Genes involved in Glucose transport |
| 0.3 | 8.4 | REACTOME CYTOSOLIC TRNA AMINOACYLATION | Genes involved in Cytosolic tRNA aminoacylation |
| 0.3 | 17.6 | REACTOME INTERFERON GAMMA SIGNALING | Genes involved in Interferon gamma signaling |
| 0.3 | 3.5 | REACTOME G ALPHA1213 SIGNALLING EVENTS | Genes involved in G alpha (12/13) signalling events |
| 0.3 | 1.9 | REACTOME TRANSFERRIN ENDOCYTOSIS AND RECYCLING | Genes involved in Transferrin endocytosis and recycling |
| 0.3 | 2.4 | REACTOME CD28 DEPENDENT PI3K AKT SIGNALING | Genes involved in CD28 dependent PI3K/Akt signaling |
| 0.3 | 1.8 | REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 2 PROMOTER | Genes involved in RNA Polymerase III Transcription Initiation From Type 2 Promoter |
| 0.3 | 56.2 | REACTOME SIGNALING BY RHO GTPASES | Genes involved in Signaling by Rho GTPases |
| 0.3 | 4.0 | REACTOME ABACAVIR TRANSPORT AND METABOLISM | Genes involved in Abacavir transport and metabolism |
| 0.2 | 4.0 | REACTOME METABOLISM OF NON CODING RNA | Genes involved in Metabolism of non-coding RNA |
| 0.2 | 22.2 | REACTOME MITOTIC PROMETAPHASE | Genes involved in Mitotic Prometaphase |
| 0.2 | 15.9 | REACTOME STRIATED MUSCLE CONTRACTION | Genes involved in Striated Muscle Contraction |
| 0.2 | 4.1 | REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY | Genes involved in Adenylate cyclase activating pathway |
| 0.2 | 2.8 | REACTOME IL 7 SIGNALING | Genes involved in Interleukin-7 signaling |
| 0.2 | 6.2 | REACTOME ZINC TRANSPORTERS | Genes involved in Zinc transporters |
| 0.2 | 2.1 | REACTOME MICRORNA MIRNA BIOGENESIS | Genes involved in MicroRNA (miRNA) Biogenesis |
| 0.2 | 6.5 | REACTOME SIGNALING BY HIPPO | Genes involved in Signaling by Hippo |
| 0.2 | 1.3 | REACTOME VEGF LIGAND RECEPTOR INTERACTIONS | Genes involved in VEGF ligand-receptor interactions |
| 0.2 | 3.8 | REACTOME METABOLISM OF POLYAMINES | Genes involved in Metabolism of polyamines |
| 0.2 | 4.0 | REACTOME RNA POL III TRANSCRIPTION TERMINATION | Genes involved in RNA Polymerase III Transcription Termination |
| 0.2 | 3.1 | REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS | Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers |
| 0.2 | 12.0 | REACTOME VOLTAGE GATED POTASSIUM CHANNELS | Genes involved in Voltage gated Potassium channels |
| 0.2 | 2.6 | REACTOME PREFOLDIN MEDIATED TRANSFER OF SUBSTRATE TO CCT TRIC | Genes involved in Prefoldin mediated transfer of substrate to CCT/TriC |
| 0.2 | 20.4 | REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 | Genes involved in Response to elevated platelet cytosolic Ca2+ |
| 0.2 | 9.8 | REACTOME INTERACTION BETWEEN L1 AND ANKYRINS | Genes involved in Interaction between L1 and Ankyrins |
| 0.2 | 10.2 | REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES | Genes involved in Antiviral mechanism by IFN-stimulated genes |
| 0.2 | 1.3 | REACTOME SPRY REGULATION OF FGF SIGNALING | Genes involved in Spry regulation of FGF signaling |
| 0.2 | 4.0 | REACTOME CHONDROITIN SULFATE BIOSYNTHESIS | Genes involved in Chondroitin sulfate biosynthesis |
| 0.2 | 6.7 | REACTOME O LINKED GLYCOSYLATION OF MUCINS | Genes involved in O-linked glycosylation of mucins |
| 0.2 | 1.5 | REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 3 PROMOTER | Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter |
| 0.2 | 2.3 | REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS | Genes involved in Proteolytic cleavage of SNARE complex proteins |
| 0.2 | 0.6 | REACTOME PROLONGED ERK ACTIVATION EVENTS | Genes involved in Prolonged ERK activation events |
| 0.2 | 4.7 | REACTOME CELL SURFACE INTERACTIONS AT THE VASCULAR WALL | Genes involved in Cell surface interactions at the vascular wall |
| 0.2 | 10.9 | REACTOME APC C CDH1 MEDIATED DEGRADATION OF CDC20 AND OTHER APC C CDH1 TARGETED PROTEINS IN LATE MITOSIS EARLY G1 | Genes involved in APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 |
| 0.2 | 0.5 | REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES | Genes involved in Cross-presentation of soluble exogenous antigens (endosomes) |
| 0.1 | 4.4 | REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI | Genes involved in Synthesis of glycosylphosphatidylinositol (GPI) |
| 0.1 | 1.9 | REACTOME P38MAPK EVENTS | Genes involved in p38MAPK events |
| 0.1 | 2.9 | REACTOME INSULIN SYNTHESIS AND PROCESSING | Genes involved in Insulin Synthesis and Processing |
| 0.1 | 2.8 | REACTOME DEADENYLATION OF MRNA | Genes involved in Deadenylation of mRNA |
| 0.1 | 4.6 | REACTOME INTEGRIN CELL SURFACE INTERACTIONS | Genes involved in Integrin cell surface interactions |
| 0.1 | 7.1 | REACTOME MITOCHONDRIAL PROTEIN IMPORT | Genes involved in Mitochondrial Protein Import |
| 0.1 | 1.0 | REACTOME ACTIVATION OF NF KAPPAB IN B CELLS | Genes involved in Activation of NF-kappaB in B Cells |
| 0.1 | 1.8 | REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING | Genes involved in Downregulation of ERBB2:ERBB3 signaling |
| 0.1 | 5.2 | REACTOME SYNTHESIS OF PA | Genes involved in Synthesis of PA |
| 0.1 | 1.4 | REACTOME REGULATION OF SIGNALING BY CBL | Genes involved in Regulation of signaling by CBL |
| 0.1 | 0.6 | REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY | Genes involved in Post-chaperonin tubulin folding pathway |
| 0.1 | 1.0 | REACTOME COPI MEDIATED TRANSPORT | Genes involved in COPI Mediated Transport |
| 0.1 | 1.6 | REACTOME EGFR DOWNREGULATION | Genes involved in EGFR downregulation |
| 0.1 | 6.0 | REACTOME POTASSIUM CHANNELS | Genes involved in Potassium Channels |
| 0.1 | 1.6 | REACTOME IL 2 SIGNALING | Genes involved in Interleukin-2 signaling |
| 0.1 | 0.9 | REACTOME HYALURONAN UPTAKE AND DEGRADATION | Genes involved in Hyaluronan uptake and degradation |
| 0.1 | 0.8 | REACTOME COSTIMULATION BY THE CD28 FAMILY | Genes involved in Costimulation by the CD28 family |
| 0.1 | 0.5 | REACTOME DOWNSTREAM SIGNAL TRANSDUCTION | Genes involved in Downstream signal transduction |
| 0.1 | 3.1 | REACTOME INTRINSIC PATHWAY FOR APOPTOSIS | Genes involved in Intrinsic Pathway for Apoptosis |
| 0.1 | 15.7 | REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION | Genes involved in Antigen processing: Ubiquitination & Proteasome degradation |
| 0.1 | 1.0 | REACTOME SIGNAL ATTENUATION | Genes involved in Signal attenuation |
| 0.1 | 3.9 | REACTOME PHASE1 FUNCTIONALIZATION OF COMPOUNDS | Genes involved in Phase 1 - Functionalization of compounds |
| 0.1 | 0.8 | REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB | Genes involved in PKA-mediated phosphorylation of CREB |
| 0.1 | 0.2 | REACTOME PROCESSING OF CAPPED INTRON CONTAINING PRE MRNA | Genes involved in Processing of Capped Intron-Containing Pre-mRNA |
| 0.1 | 1.4 | REACTOME MEIOTIC RECOMBINATION | Genes involved in Meiotic Recombination |
| 0.1 | 1.7 | REACTOME ADHERENS JUNCTIONS INTERACTIONS | Genes involved in Adherens junctions interactions |
| 0.1 | 3.4 | REACTOME RECRUITMENT OF MITOTIC CENTROSOME PROTEINS AND COMPLEXES | Genes involved in Recruitment of mitotic centrosome proteins and complexes |
| 0.1 | 1.1 | REACTOME REGULATION OF WATER BALANCE BY RENAL AQUAPORINS | Genes involved in Regulation of Water Balance by Renal Aquaporins |
| 0.0 | 1.4 | REACTOME INTERFERON ALPHA BETA SIGNALING | Genes involved in Interferon alpha/beta signaling |
| 0.0 | 0.5 | REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING | Genes involved in Downregulation of TGF-beta receptor signaling |
| 0.0 | 0.8 | REACTOME HS GAG DEGRADATION | Genes involved in HS-GAG degradation |
| 0.0 | 0.4 | REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY | Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway |
| 0.0 | 0.7 | REACTOME PURINE SALVAGE | Genes involved in Purine salvage |
| 0.0 | 0.7 | REACTOME FANCONI ANEMIA PATHWAY | Genes involved in Fanconi Anemia pathway |
| 0.0 | 0.4 | REACTOME ACTIVATION OF ATR IN RESPONSE TO REPLICATION STRESS | Genes involved in Activation of ATR in response to replication stress |
| 0.0 | 0.9 | REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS | Genes involved in Sphingolipid de novo biosynthesis |
| 0.0 | 0.4 | REACTOME SIGNALING BY BMP | Genes involved in Signaling by BMP |
| 0.0 | 0.1 | REACTOME NONSENSE MEDIATED DECAY ENHANCED BY THE EXON JUNCTION COMPLEX | Genes involved in Nonsense Mediated Decay Enhanced by the Exon Junction Complex |