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GSE58827: Dynamics of the Mouse Liver

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Results for Fli1

Z-value: 1.89

Motif logo

Transcription factors associated with Fli1

Gene Symbol Gene ID Gene Info
ENSMUSG00000016087.14 Friend leukemia integration 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Fli1mm39_v1_chr9_-_32452885_32452898-0.651.7e-05Click!

Activity profile of Fli1 motif

Sorted Z-values of Fli1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr19_-_40175709 54.83 ENSMUST00000051846.13
cytochrome P450, family 2, subfamily c, polypeptide 70
chr9_-_57590926 40.45 ENSMUST00000034860.5
cytochrome P450, family 1, subfamily a, polypeptide 2
chr8_-_25066313 33.13 ENSMUST00000121992.2
indoleamine 2,3-dioxygenase 2
chr5_-_89583469 25.48 ENSMUST00000200534.2
vitamin D binding protein
chr7_-_26638802 25.17 ENSMUST00000170227.3
cytochrome P450, family 2, subfamily a, polypeptide 22
chr7_-_13571334 16.88 ENSMUST00000108522.5
sulfotransferase family 2A, dehydroepiandrosterone (DHEA)-preferring, member 1
chr17_-_32643131 16.80 ENSMUST00000236386.2
peptidoglycan recognition protein 2
chr17_-_32643067 16.71 ENSMUST00000237130.2
peptidoglycan recognition protein 2
chr13_-_4573312 11.53 ENSMUST00000221564.2
ENSMUST00000078239.5
ENSMUST00000080361.13
aldo-keto reductase family 1, member C20
chr11_-_5865124 8.69 ENSMUST00000109823.9
ENSMUST00000109822.8
glucokinase
chr15_-_96918203 8.12 ENSMUST00000166223.2
solute carrier family 38, member 4
chr19_+_46120327 7.76 ENSMUST00000043739.6
ENSMUST00000237098.2
elongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like 3
chr7_+_13467422 7.75 ENSMUST00000086148.8
sulfotransferase family 2A, dehydroepiandrosterone (DHEA)-preferring, member 2
chr2_+_58644922 7.18 ENSMUST00000059102.13
uridine phosphorylase 2
chr6_-_146536025 6.87 ENSMUST00000037709.16
transmembrane 7 superfamily member 3
chr5_-_73496291 6.71 ENSMUST00000200830.4
ENSMUST00000201908.4
ENSMUST00000200776.4
ENSMUST00000087195.9
OCIA domain containing 2
chr13_+_4484305 6.71 ENSMUST00000021630.15
aldo-keto reductase family 1, member C6
chr17_+_79359617 6.33 ENSMUST00000233916.2
glutaminyl-peptide cyclotransferase (glutaminyl cyclase)
chr11_+_16702203 6.31 ENSMUST00000102884.10
ENSMUST00000020329.13
epidermal growth factor receptor
chr7_-_48493388 6.17 ENSMUST00000167786.4
cysteine and glycine-rich protein 3
chr9_+_111268131 5.56 ENSMUST00000111879.5
doublecortin-like kinase 3
chr15_-_96917804 5.45 ENSMUST00000231039.2
solute carrier family 38, member 4
chr5_-_73495895 5.19 ENSMUST00000202012.2
OCIA domain containing 2
chr17_+_29077385 5.17 ENSMUST00000056866.8
patatin-like phospholipase domain containing 1
chr15_+_25940781 5.09 ENSMUST00000227275.2
reticulophagy regulator 1
chr15_-_76010736 4.83 ENSMUST00000054022.12
ENSMUST00000089654.4
cDNA sequence BC024139
chr16_+_37400590 4.80 ENSMUST00000159787.8
homogentisate 1, 2-dioxygenase
chr16_+_37400500 4.55 ENSMUST00000160847.2
homogentisate 1, 2-dioxygenase
chr6_+_138117295 4.42 ENSMUST00000008684.11
microsomal glutathione S-transferase 1
chr10_-_93375832 4.40 ENSMUST00000016034.3
amidohydrolase domain containing 1
chr6_+_138117519 4.30 ENSMUST00000120939.8
ENSMUST00000204628.3
ENSMUST00000140932.2
ENSMUST00000120302.8
microsomal glutathione S-transferase 1
chr6_+_124470053 3.84 ENSMUST00000049124.10
complement component 1, r subcomponent-like
chr9_+_78137927 3.80 ENSMUST00000098537.4
glutathione S-transferase, alpha 1 (Ya)
chr18_-_20192535 3.71 ENSMUST00000075214.9
ENSMUST00000039247.11
desmocollin 2
chrX_-_135769285 3.68 ENSMUST00000058814.7
RAB9B, member RAS oncogene family
chr8_-_3770642 3.48 ENSMUST00000062037.7
C-type lectin domain family 4, member g
chr7_-_80055168 3.43 ENSMUST00000107362.10
ENSMUST00000135306.3
furin (paired basic amino acid cleaving enzyme)
chr6_-_119394634 3.02 ENSMUST00000032272.13
adiponectin receptor 2
chr10_-_127457001 2.94 ENSMUST00000049149.15
low density lipoprotein receptor-related protein 1
chr4_+_40722911 2.78 ENSMUST00000164233.8
ENSMUST00000137246.8
ENSMUST00000125442.8
DnaJ heat shock protein family (Hsp40) member A1
chr7_-_15978077 2.49 ENSMUST00000238893.2
ENSMUST00000171425.4
complement component 5a receptor 2
chr4_+_148686985 2.46 ENSMUST00000105701.9
ENSMUST00000052060.7
mannan-binding lectin serine peptidase 2
chr17_-_45906768 2.39 ENSMUST00000164618.8
ENSMUST00000097317.10
ENSMUST00000170113.8
solute carrier family 29 (nucleoside transporters), member 1
chr14_+_53791444 2.35 ENSMUST00000198297.2
T cell receptor alpha variable 14-1
chr9_+_44966464 2.35 ENSMUST00000114664.8
myelin protein zero-like 3
chr8_-_71938598 2.30 ENSMUST00000093450.6
ENSMUST00000213382.2
anoctamin 8
chr12_+_87561085 2.28 ENSMUST00000110152.3
eukaryotic translation initiation factor 1A domain containing 8
chr2_-_86940289 2.22 ENSMUST00000215828.3
olfactory receptor 259
chr7_-_19556612 2.10 ENSMUST00000120537.8
B cell leukemia/lymphoma 3
chr10_-_127456791 2.09 ENSMUST00000118455.2
ENSMUST00000121829.8
low density lipoprotein receptor-related protein 1
chr17_-_31363245 2.07 ENSMUST00000024826.8
trefoil factor 2 (spasmolytic protein 1)
chr7_-_140001552 2.07 ENSMUST00000213801.2
olfactory receptor 532
chr11_-_100650566 2.02 ENSMUST00000107361.9
potassium voltage-gated channel, subfamily H (eag-related), member 4
chr9_-_64928927 2.02 ENSMUST00000036615.7
3-hydroxyacyl-CoA dehydratase 3
chr5_+_43829631 1.97 ENSMUST00000125866.4
coiled-coil and C2 domain containing 2A
chr6_-_119394436 1.94 ENSMUST00000189710.2
adiponectin receptor 2
chr18_-_75830595 1.89 ENSMUST00000165559.3
CBP80/20-dependent translation initiation factor
chr6_-_57668992 1.85 ENSMUST00000053386.6
Pigy upstream reading frame
chr4_-_130031421 1.79 ENSMUST00000164887.3
hypocretin (orexin) receptor 1
chrX_-_71699740 1.78 ENSMUST00000055966.13
gamma-aminobutyric acid (GABA) A receptor, subunit alpha 3
chr15_-_76406602 1.69 ENSMUST00000096365.5
scratch family zinc finger 1
chr14_+_53878158 1.59 ENSMUST00000179267.4
T cell receptor alpha variable 14-2
chr4_+_40723083 1.57 ENSMUST00000149794.2
DnaJ heat shock protein family (Hsp40) member A1
chr13_+_42862957 1.50 ENSMUST00000066928.12
ENSMUST00000148891.8
phosphatase and actin regulator 1
chr7_-_6525801 1.48 ENSMUST00000213504.2
ENSMUST00000216447.2
ENSMUST00000213656.2
ENSMUST00000207820.3
olfactory receptor 1349
chr4_+_43406435 1.48 ENSMUST00000098106.9
ENSMUST00000139198.2
RUN and SH3 domain containing 2
chr10_+_19810037 1.48 ENSMUST00000095806.10
ENSMUST00000120259.8
mitogen-activated protein kinase kinase kinase 5
chr1_+_182591771 1.44 ENSMUST00000193660.6
sushi domain containing 4
chr17_-_36014863 1.43 ENSMUST00000148065.8
discoidin domain receptor family, member 1
chr9_+_118307412 1.42 ENSMUST00000035020.15
eomesodermin
chr9_+_118307918 1.42 ENSMUST00000150633.2
eomesodermin
chr16_+_48104098 1.37 ENSMUST00000096045.9
ENSMUST00000050705.4
developmental pluripotency associated 4
chr7_-_4606104 1.36 ENSMUST00000049113.14
protein tyrosine phosphatase, receptor type, H
chr14_-_55204023 1.35 ENSMUST00000124930.8
myosin, heavy polypeptide 6, cardiac muscle, alpha
chr3_-_89820451 1.35 ENSMUST00000029559.7
ENSMUST00000197679.5
interleukin 6 receptor, alpha
chr5_-_135378896 1.34 ENSMUST00000201534.2
ENSMUST00000044972.11
FK506 binding protein 6
chr5_+_127709302 1.33 ENSMUST00000118139.3
glycosyltransferase 1 domain containing 1
chr10_+_84591919 1.31 ENSMUST00000060397.13
regulatory factor X, 4 (influences HLA class II expression)
chr14_-_55204054 1.31 ENSMUST00000226297.2
myosin, heavy polypeptide 6, cardiac muscle, alpha
chr12_+_87665639 1.31 ENSMUST00000164838.3
eukaryotic translation initiation factor 1A domain containing 6
chr17_-_24863956 1.31 ENSMUST00000019684.13
solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 2
chrX_+_140258381 1.30 ENSMUST00000112931.8
ENSMUST00000112930.8
collagen, type IV, alpha 5
chr3_+_144276154 1.28 ENSMUST00000082437.11
selenoprotein F
chr6_-_77956635 1.26 ENSMUST00000161846.8
ENSMUST00000160894.8
catenin (cadherin associated protein), alpha 2
chr19_+_4264470 1.25 ENSMUST00000237171.2
predicted gene, 45928
chr17_-_24863907 1.21 ENSMUST00000234505.2
solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 2
chr2_-_121786573 1.21 ENSMUST00000104936.4
MAGE family member B3
chr14_-_46628033 1.18 ENSMUST00000074077.12
bone morphogenetic protein 4
chr4_+_33078796 1.14 ENSMUST00000131920.8
gamma-aminobutyric acid (GABA) C receptor, subunit rho 2
chr14_+_56640038 1.13 ENSMUST00000095793.3
ENSMUST00000223627.2
ring finger protein 17
chr5_-_135378729 1.13 ENSMUST00000201784.4
ENSMUST00000201791.4
FK506 binding protein 6
chr14_+_55120777 1.12 ENSMUST00000022806.10
BCL2-like 2
chr14_+_53404083 1.11 ENSMUST00000196639.2
ENSMUST00000177578.2
T cell receptor alpha variable 14N-1
chr19_-_56378309 1.10 ENSMUST00000166203.2
ENSMUST00000167239.8
nebulin-related anchoring protein
chr5_+_123390149 1.08 ENSMUST00000121964.8
WD repeat domain 66
chr9_+_44018583 1.07 ENSMUST00000152956.8
ENSMUST00000114815.3
ENSMUST00000206295.2
ENSMUST00000206769.2
ENSMUST00000205500.2
C1q and tumor necrosis factor related protein 5
chr2_+_119378178 1.03 ENSMUST00000014221.13
ENSMUST00000119172.2
calcineurin-like EF hand protein 1
chr9_+_118307250 1.03 ENSMUST00000111763.8
eomesodermin
chr1_+_182591425 1.02 ENSMUST00000155229.7
ENSMUST00000153348.8
sushi domain containing 4
chr12_+_87783347 1.01 ENSMUST00000110149.2
eukaryotic translation initiation factor 1A domain containing 2
chr10_+_26105605 0.99 ENSMUST00000218301.2
ENSMUST00000164660.8
ENSMUST00000060716.6
sterile alpha motif domain containing 3
chr14_-_46627957 0.98 ENSMUST00000100676.3
bone morphogenetic protein 4
chr9_+_44018551 0.98 ENSMUST00000114821.9
ENSMUST00000114818.9
C1q and tumor necrosis factor related protein 5
chr7_-_108471586 0.97 ENSMUST00000216500.2
olfactory receptor 517
chr17_-_24428351 0.97 ENSMUST00000024931.6
netrin 3
chr14_+_53093071 0.95 ENSMUST00000181038.3
ENSMUST00000187138.2
T cell receptor alpha variable 14D-1
chr17_+_6157154 0.93 ENSMUST00000149756.8
tubby like protein 4
chr11_+_87486472 0.91 ENSMUST00000134216.3
myotubularin related protein 4
chr9_+_44394080 0.91 ENSMUST00000220303.2
B cell CLL/lymphoma 9-like
chr6_-_77956499 0.89 ENSMUST00000159626.8
ENSMUST00000075340.12
ENSMUST00000162273.2
catenin (cadherin associated protein), alpha 2
chr12_-_88290796 0.88 ENSMUST00000218054.3
eukaryotic translation initiation factor 1A domain containing 15
chr19_+_4264437 0.88 ENSMUST00000235355.2
cardiotrophin-like cytokine factor 1
chr10_+_84753480 0.84 ENSMUST00000038523.15
ENSMUST00000214693.2
ENSMUST00000095385.5
RIC8 guanine nucleotide exchange factor B
chr8_-_45863572 0.84 ENSMUST00000209651.2
ENSMUST00000211370.2
ENSMUST00000034056.12
ENSMUST00000167106.3
toll-like receptor 3
chr10_+_21869776 0.83 ENSMUST00000092673.11
serum/glucocorticoid regulated kinase 1
chr14_-_55204092 0.83 ENSMUST00000081857.14
myosin, heavy polypeptide 6, cardiac muscle, alpha
chr16_-_10884005 0.81 ENSMUST00000162323.2
LPS-induced TN factor
chr3_-_144275897 0.81 ENSMUST00000043325.9
heparan sulfate 2-O-sulfotransferase 1
chr2_-_119378108 0.80 ENSMUST00000060009.9
exonuclease 3'-5' domain containing 1
chr16_-_28571820 0.79 ENSMUST00000232352.2
fibroblast growth factor 12
chr7_+_104506216 0.79 ENSMUST00000067695.8
ubiquitin specific peptidase 17-like A
chr1_+_54289833 0.79 ENSMUST00000027128.11
coiled-coil domain containing 150
chr1_+_170060318 0.78 ENSMUST00000162752.2
SH2 domain containing 1B2
chr3_+_156267429 0.77 ENSMUST00000074015.11
neuronal growth regulator 1
chr12_-_118265163 0.76 ENSMUST00000221844.2
trans-acting transcription factor 4
chr2_+_152804405 0.75 ENSMUST00000099197.9
ENSMUST00000103155.10
tubulin tyrosine ligase-like family, member 9
chr2_+_79465696 0.75 ENSMUST00000111785.9
ITPR interacting domain containing 2
chr19_+_59447950 0.73 ENSMUST00000174353.2
empty spiracles homeobox 2
chr5_-_66330394 0.73 ENSMUST00000201544.4
RNA binding motif protein 47
chr6_+_57183497 0.72 ENSMUST00000227298.2
vomeronasal 1 receptor 13
chr2_+_79465761 0.71 ENSMUST00000111788.8
ENSMUST00000111784.9
ITPR interacting domain containing 2
chr12_-_115964081 0.71 ENSMUST00000103552.2
immunoglobulin heavy variable 1-85
chr3_+_156267587 0.70 ENSMUST00000041425.12
ENSMUST00000106065.2
neuronal growth regulator 1
chr10_+_102348076 0.68 ENSMUST00000219445.2
Ras association (RalGDS/AF-6) domain family (N-terminal) member 9
chr9_+_44018520 0.68 ENSMUST00000114816.8
C1q and tumor necrosis factor related protein 5
chr6_-_88423464 0.66 ENSMUST00000204459.3
ENSMUST00000203213.3
ENSMUST00000205179.3
ENSMUST00000165242.4
eukaryotic elongation factor, selenocysteine-tRNA-specific
chr5_-_151157283 0.65 ENSMUST00000126770.2
StAR-related lipid transfer (START) domain containing 13
chr11_+_17207558 0.65 ENSMUST00000000594.9
ENSMUST00000156784.2
C1D nuclear receptor co-repressor
chr2_-_38177182 0.65 ENSMUST00000130472.8
DENN/MADD domain containing 1A
chr10_-_3217767 0.63 ENSMUST00000170893.3
histocompatibility 60c
chr10_-_3217718 0.62 ENSMUST00000216211.2
histocompatibility 60c
chr18_+_47054867 0.62 ENSMUST00000234910.2
ADP-ribosylation factor-like 14 effector protein-like
chr9_-_117843417 0.62 ENSMUST00000238919.2
zinc finger, CW type with PWWP domain 2
chr1_+_42992109 0.61 ENSMUST00000179766.3
G protein-coupled receptor 45
chr11_-_53525520 0.59 ENSMUST00000020650.2
interleukin 13
chr1_-_126420659 0.59 ENSMUST00000161954.8
NCK-associated protein 5
chr10_+_24471340 0.58 ENSMUST00000020171.12
cellular communication network factor 2
chr15_+_102884874 0.58 ENSMUST00000173306.2
homeobox C9
chr7_+_34885782 0.57 ENSMUST00000135452.8
ENSMUST00000001854.12
solute carrier family 7 (cationic amino acid transporter, y+ system), member 10
chr14_-_7666348 0.56 ENSMUST00000224491.2
NIMA (never in mitosis gene a)- related kinase 10
chr3_-_129518723 0.56 ENSMUST00000199615.5
ENSMUST00000197079.5
epidermal growth factor
chr2_-_32976378 0.56 ENSMUST00000049618.9
GTPase activating RANGAP domain-like 3
chr5_-_147244074 0.55 ENSMUST00000031650.4
caudal type homeobox 2
chr4_-_150085722 0.54 ENSMUST00000153394.2
hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase)
chr11_-_100583265 0.54 ENSMUST00000153494.2
zinc finger protein 385C
chr10_-_62561865 0.54 ENSMUST00000133371.8
storkhead box 1
chr9_-_8004586 0.53 ENSMUST00000086580.12
ENSMUST00000065353.13
yes-associated protein 1
chr10_+_82190078 0.52 ENSMUST00000211099.2
predicted gene 4924
chr7_-_104426677 0.51 ENSMUST00000211384.2
ENSMUST00000053464.9
ubiquitin specific peptidase 17-like E
chr14_-_101437750 0.51 ENSMUST00000187304.2
proline rich 30
chr15_-_98660873 0.50 ENSMUST00000156572.3
ADP-ribosylation factor 3
chr1_-_44118902 0.50 ENSMUST00000238662.2
predicted gene 8251
chr16_+_91184661 0.49 ENSMUST00000139503.2
interferon (alpha and beta) receptor 2
chr4_+_42655251 0.49 ENSMUST00000177785.3
chemokine (C-C motif) ligand 27b
chr13_-_99584091 0.48 ENSMUST00000223725.2
microtubule-associated protein 1B
chr1_+_44590791 0.48 ENSMUST00000160854.8
GULP, engulfment adaptor PTB domain containing 1
chr11_-_100244866 0.47 ENSMUST00000173630.8
huntingtin-associated protein 1
chr11_-_100650768 0.46 ENSMUST00000107363.3
potassium voltage-gated channel, subfamily H (eag-related), member 4
chr4_+_155874896 0.46 ENSMUST00000165000.8
ankyrin repeat domain 65
chr6_+_41512010 0.46 ENSMUST00000103288.2
T cell receptor beta joining 1-5
chr9_-_109397316 0.46 ENSMUST00000198112.2
ENSMUST00000198397.5
ENSMUST00000056745.12
F-box and WD-40 domain protein 15
chr5_+_92285748 0.45 ENSMUST00000031355.10
ENSMUST00000202155.2
USO1 vesicle docking factor
chr9_-_109024588 0.45 ENSMUST00000199102.2
F-box and WD-40 domain protein 13
chr6_+_145879839 0.44 ENSMUST00000032383.14
sarcospan
chr2_+_121786892 0.42 ENSMUST00000110578.8
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase like 2
chr16_+_3648742 0.41 ENSMUST00000214238.2
ENSMUST00000214590.2
olfactory receptor 15
chrX_+_31839202 0.41 ENSMUST00000179991.3
BTB domain containing 35, family member 2
chr5_-_151157233 0.41 ENSMUST00000129088.8
StAR-related lipid transfer (START) domain containing 13
chr11_+_56902658 0.41 ENSMUST00000094179.11
glutamate receptor, ionotropic, AMPA1 (alpha 1)
chr2_+_121787131 0.40 ENSMUST00000110574.8
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase like 2
chrX_+_72527208 0.40 ENSMUST00000033741.15
ENSMUST00000169489.2
biglycan
chr2_+_65676111 0.40 ENSMUST00000122912.8
cysteine-serine-rich nuclear protein 3
chr10_+_98750268 0.40 ENSMUST00000219557.2
ATPase, Ca++ transporting, plasma membrane 1
chr15_-_76406102 0.39 ENSMUST00000164703.2
scratch family zinc finger 1
chrX_+_33094635 0.39 ENSMUST00000177912.2
BTB domain containing 35, family member 13
chrX_+_30768610 0.39 ENSMUST00000179532.2
BTB domain containing 35, family member 29
chr4_+_42158092 0.39 ENSMUST00000098122.3
predicted gene 13306
chr6_-_126141911 0.39 ENSMUST00000204542.3
neurotrophin 3
chr6_-_28831746 0.39 ENSMUST00000062304.7
leucine rich repeat containing 4
chr11_+_56902624 0.39 ENSMUST00000036315.16
glutamate receptor, ionotropic, AMPA1 (alpha 1)
chr2_-_38177359 0.39 ENSMUST00000102787.10
DENN/MADD domain containing 1A
chrX_-_33014777 0.38 ENSMUST00000186329.2
BTB domain containing 35, family member 15
chrX_-_33139812 0.38 ENSMUST00000105117.3
BTB domain containing 35, family member 14
chr2_+_158344553 0.37 ENSMUST00000109484.2
adipogenin
chrX_-_31034822 0.37 ENSMUST00000238426.2
BTB domain containing 35, family member 19
chrX_-_33580888 0.37 ENSMUST00000238632.2
BTB domain containing 35, family member 9
chr6_+_122490577 0.37 ENSMUST00000118626.8
microfibrillar associated protein 5
chr10_-_71121083 0.36 ENSMUST00000020085.7
ubiquitin-conjugating enzyme E2D 1
chrX_+_32070863 0.35 ENSMUST00000238237.2
BTB domain containing 35, family member 1
chr14_-_20714634 0.35 ENSMUST00000119483.2
synaptopodin 2-like

Network of associatons between targets according to the STRING database.

First level regulatory network of Fli1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
10.1 40.5 GO:0018894 dibenzo-p-dioxin metabolic process(GO:0018894)
5.6 33.5 GO:0032827 peptidoglycan metabolic process(GO:0000270) peptidoglycan catabolic process(GO:0009253) negative regulation of natural killer cell differentiation(GO:0032824) negative regulation of natural killer cell differentiation involved in immune response(GO:0032827)
3.0 33.1 GO:0042436 tryptophan catabolic process(GO:0006569) tryptophan catabolic process to kynurenine(GO:0019441) indole-containing compound catabolic process(GO:0042436) indolalkylamine catabolic process(GO:0046218)
2.4 80.0 GO:0019373 epoxygenase P450 pathway(GO:0019373)
2.2 6.7 GO:0071395 response to jasmonic acid(GO:0009753) cellular response to jasmonic acid stimulus(GO:0071395)
2.2 8.7 GO:0071449 cellular response to lipid hydroperoxide(GO:0071449)
2.1 6.3 GO:0018199 peptidyl-glutamine modification(GO:0018199)
2.1 6.2 GO:1903920 positive regulation of actin filament severing(GO:1903920)
1.7 8.7 GO:0009732 detection of carbohydrate stimulus(GO:0009730) detection of hexose stimulus(GO:0009732) detection of monosaccharide stimulus(GO:0034287) detection of glucose(GO:0051594)
1.3 3.9 GO:0002302 CD8-positive, alpha-beta T cell differentiation involved in immune response(GO:0002302)
1.3 5.0 GO:1905167 positive regulation of lysosomal protein catabolic process(GO:1905167)
1.2 25.5 GO:0042359 vitamin D metabolic process(GO:0042359)
1.1 6.3 GO:0070459 prolactin secretion(GO:0070459) regulation of protein kinase C activity(GO:1900019) positive regulation of protein kinase C activity(GO:1900020)
1.0 9.4 GO:0006572 tyrosine catabolic process(GO:0006572)
0.9 4.4 GO:0006548 histidine catabolic process(GO:0006548)
0.9 3.5 GO:0007522 visceral muscle development(GO:0007522)
0.9 3.4 GO:0090472 dibasic protein processing(GO:0090472)
0.8 2.5 GO:1902623 negative regulation of neutrophil migration(GO:1902623)
0.7 16.9 GO:0051923 sulfation(GO:0051923)
0.7 2.2 GO:1902460 intermediate mesoderm development(GO:0048389) cloacal septation(GO:0060197) pattern specification involved in mesonephros development(GO:0061227) anterior/posterior pattern specification involved in kidney development(GO:0072098) regulation of mesenchymal stem cell proliferation(GO:1902460) positive regulation of mesenchymal stem cell proliferation(GO:1902462) cardiac jelly development(GO:1905072) negative regulation of cell proliferation involved in heart morphogenesis(GO:2000137)
0.7 2.1 GO:0045074 interleukin-10 biosynthetic process(GO:0042091) regulation of interleukin-10 biosynthetic process(GO:0045074)
0.6 7.8 GO:0019367 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.6 2.5 GO:0030450 regulation of complement activation, classical pathway(GO:0030450)
0.6 5.1 GO:0061709 reticulophagy(GO:0061709)
0.5 4.4 GO:0042769 DNA damage response, detection of DNA damage(GO:0042769)
0.5 5.0 GO:0061042 vascular wound healing(GO:0061042)
0.4 1.3 GO:0010536 positive regulation of activation of Janus kinase activity(GO:0010536)
0.4 3.7 GO:0086073 bundle of His cell-Purkinje myocyte adhesion involved in cell communication(GO:0086073)
0.4 2.0 GO:1904491 protein localization to ciliary transition zone(GO:1904491)
0.3 2.4 GO:0015862 uridine transport(GO:0015862)
0.3 2.0 GO:0046726 positive regulation by virus of viral protein levels in host cell(GO:0046726)
0.3 2.1 GO:0060455 negative regulation of gastric acid secretion(GO:0060455)
0.3 1.0 GO:0032417 positive regulation of sodium:proton antiporter activity(GO:0032417)
0.2 14.1 GO:0003333 amino acid transmembrane transport(GO:0003333)
0.2 1.3 GO:0021914 negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning(GO:0021914)
0.2 1.1 GO:0097498 endothelial tube lumen extension(GO:0097498)
0.2 0.8 GO:0043396 corticotropin-releasing hormone secretion(GO:0043396) regulation of corticotropin-releasing hormone secretion(GO:0043397) positive regulation of corticotropin-releasing hormone secretion(GO:0051466)
0.2 0.6 GO:0033861 negative regulation of NAD(P)H oxidase activity(GO:0033861)
0.2 2.5 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.2 1.0 GO:0032483 regulation of Rab protein signal transduction(GO:0032483)
0.2 0.8 GO:0030202 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014) heparin metabolic process(GO:0030202)
0.2 0.8 GO:1905150 regulation of voltage-gated sodium channel activity(GO:1905150)
0.2 3.5 GO:0002710 negative regulation of T cell mediated immunity(GO:0002710)
0.2 1.1 GO:0002282 microglial cell activation involved in immune response(GO:0002282) regulation of dendritic cell cytokine production(GO:0002730)
0.1 3.3 GO:0034587 piRNA metabolic process(GO:0034587)
0.1 1.2 GO:0060011 Sertoli cell proliferation(GO:0060011)
0.1 3.8 GO:0035634 response to stilbenoid(GO:0035634)
0.1 2.1 GO:0051823 regulation of synapse structural plasticity(GO:0051823)
0.1 2.5 GO:0038063 collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063)
0.1 0.5 GO:0071500 cellular response to nitrosative stress(GO:0071500)
0.1 1.3 GO:0035092 sperm chromatin condensation(GO:0035092)
0.1 0.4 GO:1902528 regulation of protein linear polyubiquitination(GO:1902528) positive regulation of protein linear polyubiquitination(GO:1902530)
0.1 0.5 GO:0032901 positive regulation of neurotrophin production(GO:0032901)
0.1 0.6 GO:1900127 positive regulation of hyaluronan biosynthetic process(GO:1900127)
0.1 2.5 GO:0014067 negative regulation of phosphatidylinositol 3-kinase signaling(GO:0014067)
0.1 0.3 GO:0070268 cornification(GO:0070268)
0.1 1.4 GO:0060484 lung-associated mesenchyme development(GO:0060484)
0.1 1.5 GO:1902170 cellular response to reactive nitrogen species(GO:1902170)
0.1 0.4 GO:0007403 glial cell fate determination(GO:0007403)
0.1 0.5 GO:0048280 vesicle fusion with Golgi apparatus(GO:0048280)
0.1 0.7 GO:0006451 selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)
0.1 0.5 GO:0072307 metanephric nephron tubule epithelial cell differentiation(GO:0072257) regulation of metanephric nephron tubule epithelial cell differentiation(GO:0072307)
0.1 2.9 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.1 0.3 GO:0014886 transition between slow and fast fiber(GO:0014886)
0.1 0.4 GO:1990034 calcium ion export from cell(GO:1990034)
0.1 0.7 GO:0016554 cytidine to uridine editing(GO:0016554)
0.1 6.4 GO:1900181 negative regulation of protein localization to nucleus(GO:1900181)
0.1 0.7 GO:1903546 protein localization to photoreceptor outer segment(GO:1903546)
0.1 0.8 GO:0043402 glucocorticoid mediated signaling pathway(GO:0043402)
0.0 11.5 GO:0006694 steroid biosynthetic process(GO:0006694)
0.0 7.8 GO:0008202 steroid metabolic process(GO:0008202)
0.0 1.8 GO:0045187 regulation of circadian sleep/wake cycle, sleep(GO:0045187)
0.0 6.7 GO:0009166 nucleotide catabolic process(GO:0009166)
0.0 0.3 GO:0060467 negative regulation of fertilization(GO:0060467)
0.0 0.6 GO:0014807 regulation of somitogenesis(GO:0014807)
0.0 0.2 GO:1903575 cornified envelope assembly(GO:1903575)
0.0 0.6 GO:0007342 fusion of sperm to egg plasma membrane(GO:0007342)
0.0 0.2 GO:1900245 positive regulation of MDA-5 signaling pathway(GO:1900245)
0.0 0.7 GO:0001911 negative regulation of leukocyte mediated cytotoxicity(GO:0001911) negative regulation of natural killer cell mediated cytotoxicity(GO:0045953)
0.0 1.3 GO:0001913 T cell mediated cytotoxicity(GO:0001913)
0.0 3.7 GO:0042147 retrograde transport, endosome to Golgi(GO:0042147)
0.0 0.4 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.0 0.5 GO:0006098 pentose-phosphate shunt(GO:0006098)
0.0 0.7 GO:0021542 dentate gyrus development(GO:0021542)
0.0 1.8 GO:0006506 GPI anchor biosynthetic process(GO:0006506)
0.0 4.7 GO:0006958 complement activation, classical pathway(GO:0006958)
0.0 0.5 GO:0061162 establishment of monopolar cell polarity(GO:0061162)
0.0 0.2 GO:0010578 regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway(GO:0010578) positive regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway(GO:0010579)
0.0 0.1 GO:0008626 granzyme-mediated apoptotic signaling pathway(GO:0008626)
0.0 0.4 GO:1902916 positive regulation of protein polyubiquitination(GO:1902916)
0.0 0.8 GO:0097435 fibril organization(GO:0097435)
0.0 2.1 GO:2001222 regulation of neuron migration(GO:2001222)
0.0 0.3 GO:0034551 mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122) respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551)
0.0 0.9 GO:0061512 protein localization to cilium(GO:0061512)
0.0 0.4 GO:0097119 postsynaptic density protein 95 clustering(GO:0097119)
0.0 0.6 GO:0000460 maturation of 5.8S rRNA(GO:0000460)
0.0 0.3 GO:0046475 glycerophospholipid catabolic process(GO:0046475)
0.0 2.3 GO:0006821 chloride transport(GO:0006821)
0.0 0.8 GO:0060292 long term synaptic depression(GO:0060292)
0.0 0.7 GO:0006890 retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)
0.0 1.0 GO:0007520 myoblast fusion(GO:0007520)
0.0 0.9 GO:0030512 negative regulation of transforming growth factor beta receptor signaling pathway(GO:0030512)
0.0 0.3 GO:0035455 response to interferon-alpha(GO:0035455)
0.0 0.4 GO:0046827 positive regulation of protein export from nucleus(GO:0046827)
0.0 0.0 GO:1902774 late endosome to lysosome transport(GO:1902774)
0.0 0.2 GO:0044458 motile cilium assembly(GO:0044458)
0.0 0.0 GO:0060690 epithelial cell differentiation involved in salivary gland development(GO:0060690)
0.0 8.2 GO:0007608 sensory perception of smell(GO:0007608)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 6.3 GO:0097487 multivesicular body, internal vesicle(GO:0097487)
0.7 7.2 GO:0045098 type III intermediate filament(GO:0045098)
0.5 8.7 GO:0045180 basal cortex(GO:0045180)
0.4 2.1 GO:0033257 Bcl3/NF-kappaB2 complex(GO:0033257)
0.3 1.3 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.2 1.5 GO:1990604 IRE1-TRAF2-ASK1 complex(GO:1990604)
0.2 4.1 GO:0012510 trans-Golgi network transport vesicle membrane(GO:0012510)
0.2 0.8 GO:0098559 cytoplasmic side of early endosome membrane(GO:0098559)
0.2 1.3 GO:0098645 collagen type IV trimer(GO:0005587) network-forming collagen trimer(GO:0098642) collagen network(GO:0098645) basement membrane collagen trimer(GO:0098651)
0.2 0.8 GO:0097058 CRLF-CLCF1 complex(GO:0097058)
0.2 0.8 GO:0044308 axonal spine(GO:0044308)
0.2 1.2 GO:0005927 muscle tendon junction(GO:0005927)
0.1 3.5 GO:0005859 muscle myosin complex(GO:0005859)
0.1 0.5 GO:0071148 TEAD-1-YAP complex(GO:0071148) TEAD-2-YAP complex(GO:0071149)
0.1 3.7 GO:0030057 desmosome(GO:0030057)
0.1 0.8 GO:1990923 PET complex(GO:1990923)
0.1 2.9 GO:1902711 GABA-A receptor complex(GO:1902711)
0.1 2.0 GO:0036038 MKS complex(GO:0036038)
0.1 1.8 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.1 1.2 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.1 26.4 GO:0072562 blood microparticle(GO:0072562)
0.1 8.7 GO:0005778 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.1 0.3 GO:0034667 integrin alpha3-beta1 complex(GO:0034667)
0.1 12.1 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)
0.0 2.7 GO:0016328 lateral plasma membrane(GO:0016328)
0.0 4.2 GO:0005811 lipid particle(GO:0005811)
0.0 3.1 GO:0045335 phagocytic vesicle(GO:0045335)
0.0 0.4 GO:0032591 dendritic spine membrane(GO:0032591)
0.0 1.4 GO:0005902 microvillus(GO:0005902)
0.0 1.0 GO:0030665 clathrin-coated vesicle membrane(GO:0030665)
0.0 0.3 GO:0005750 mitochondrial respiratory chain complex III(GO:0005750)
0.0 0.6 GO:0000178 exosome (RNase complex)(GO:0000178)
0.0 1.3 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 11.9 GO:0005743 mitochondrial inner membrane(GO:0005743)
0.0 9.5 GO:0016323 basolateral plasma membrane(GO:0016323)
0.0 48.8 GO:0005783 endoplasmic reticulum(GO:0005783)
0.0 3.6 GO:0030018 Z disc(GO:0030018)
0.0 0.2 GO:0035686 sperm fibrous sheath(GO:0035686)
0.0 0.5 GO:0043196 varicosity(GO:0043196)
0.0 0.4 GO:0016010 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0 1.3 GO:0032420 stereocilium(GO:0032420)
0.0 2.5 GO:0000795 synaptonemal complex(GO:0000795)
0.0 0.6 GO:0097440 apical dendrite(GO:0097440)
0.0 0.7 GO:0001917 photoreceptor inner segment(GO:0001917)
0.0 0.6 GO:0016235 aggresome(GO:0016235)
0.0 45.0 GO:0070062 extracellular exosome(GO:0070062)
0.0 13.0 GO:0031226 intrinsic component of plasma membrane(GO:0031226)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
11.0 33.1 GO:0033754 indoleamine 2,3-dioxygenase activity(GO:0033754)
6.7 40.5 GO:0034875 oxidoreductase activity, acting on CH or CH2 groups, quinone or similar compound as acceptor(GO:0033695) caffeine oxidase activity(GO:0034875)
6.4 25.5 GO:1902271 D3 vitamins binding(GO:1902271)
5.6 33.5 GO:0016019 N-acetylmuramoyl-L-alanine amidase activity(GO:0008745) peptidoglycan receptor activity(GO:0016019)
2.5 80.0 GO:0008392 arachidonic acid epoxygenase activity(GO:0008392)
2.4 16.9 GO:0050656 alcohol sulfotransferase activity(GO:0004027) 3'-phosphoadenosine 5'-phosphosulfate binding(GO:0050656)
2.2 6.7 GO:0047006 17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity(GO:0047006)
1.6 6.3 GO:0005006 epidermal growth factor-activated receptor activity(GO:0005006)
1.2 7.2 GO:0004850 uridine phosphorylase activity(GO:0004850)
1.0 5.0 GO:0097003 adipokinetic hormone receptor activity(GO:0097003)
0.9 6.2 GO:0061629 RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629)
0.9 8.7 GO:0004396 glucokinase activity(GO:0004340) hexokinase activity(GO:0004396)
0.8 2.5 GO:0001847 opsonin receptor activity(GO:0001847)
0.6 7.8 GO:0102337 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.5 3.5 GO:0030899 calcium-dependent ATPase activity(GO:0030899)
0.5 4.4 GO:0016812 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides(GO:0016812)
0.5 4.4 GO:0055131 C3HC4-type RING finger domain binding(GO:0055131)
0.4 1.3 GO:0019981 interleukin-6 receptor activity(GO:0004915) interleukin-6 binding(GO:0019981)
0.4 11.5 GO:0004033 aldo-keto reductase (NADP) activity(GO:0004033)
0.4 12.5 GO:1900750 glutathione binding(GO:0043295) oligopeptide binding(GO:1900750)
0.4 2.0 GO:0102344 3-hydroxy-behenoyl-CoA dehydratase activity(GO:0102344) 3-hydroxy-lignoceroyl-CoA dehydratase activity(GO:0102345)
0.4 1.8 GO:0016499 orexin receptor activity(GO:0016499)
0.3 5.0 GO:0032050 clathrin heavy chain binding(GO:0032050)
0.3 9.4 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen(GO:0016701) oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.2 3.8 GO:0048406 nerve growth factor binding(GO:0048406)
0.2 0.8 GO:0030023 extracellular matrix constituent conferring elasticity(GO:0030023)
0.2 0.5 GO:0047936 glucose 1-dehydrogenase [NAD(P)] activity(GO:0047936)
0.2 2.2 GO:0039706 co-receptor binding(GO:0039706) BMP receptor binding(GO:0070700)
0.2 0.5 GO:0031728 CCR3 chemokine receptor binding(GO:0031728)
0.1 2.1 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.1 2.7 GO:0004806 triglyceride lipase activity(GO:0004806)
0.1 8.6 GO:0008146 sulfotransferase activity(GO:0008146)
0.1 2.5 GO:0001846 opsonin binding(GO:0001846)
0.1 2.5 GO:0005527 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.1 3.5 GO:0030247 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.1 2.9 GO:0004890 GABA-A receptor activity(GO:0004890)
0.1 1.2 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
0.1 1.4 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.1 0.8 GO:0043423 3-phosphoinositide-dependent protein kinase binding(GO:0043423)
0.1 14.1 GO:0015171 amino acid transmembrane transporter activity(GO:0015171)
0.1 0.8 GO:0099583 AMPA glutamate receptor activity(GO:0004971) neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration(GO:0099583) transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315)
0.1 1.3 GO:0046703 natural killer cell lectin-like receptor binding(GO:0046703)
0.1 1.3 GO:0008379 thioredoxin peroxidase activity(GO:0008379)
0.1 0.8 GO:0005127 ciliary neurotrophic factor receptor binding(GO:0005127)
0.1 2.4 GO:0005337 nucleoside transmembrane transporter activity(GO:0005337)
0.1 2.3 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.1 2.5 GO:0050750 low-density lipoprotein particle receptor binding(GO:0050750)
0.1 0.7 GO:0035368 selenocysteine insertion sequence binding(GO:0035368)
0.1 0.5 GO:0005519 cytoskeletal regulatory protein binding(GO:0005519)
0.1 0.3 GO:0004904 interferon receptor activity(GO:0004904) type I interferon receptor activity(GO:0004905) type I interferon binding(GO:0019962)
0.0 1.2 GO:0051400 BH domain binding(GO:0051400)
0.0 0.5 GO:0043121 neurotrophin binding(GO:0043121)
0.0 1.2 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.0 0.3 GO:0046920 alpha-(1->3)-fucosyltransferase activity(GO:0046920)
0.0 0.3 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.0 2.7 GO:0019003 GDP binding(GO:0019003)
0.0 1.5 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 0.3 GO:1901612 cardiolipin binding(GO:1901612)
0.0 0.3 GO:0097200 cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.0 0.6 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 3.9 GO:0001191 transcriptional repressor activity, RNA polymerase II transcription factor binding(GO:0001191)
0.0 2.5 GO:0005249 voltage-gated potassium channel activity(GO:0005249)
0.0 1.0 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 0.4 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.0 4.9 GO:0005549 odorant binding(GO:0005549)
0.0 3.3 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 0.6 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.0 0.6 GO:0043236 laminin binding(GO:0043236)
0.0 0.8 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.0 0.1 GO:0004118 cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118)
0.0 1.5 GO:0004843 thiol-dependent ubiquitin-specific protease activity(GO:0004843)
0.0 0.5 GO:0070064 proline-rich region binding(GO:0070064)
0.0 0.2 GO:0030976 thiamine pyrophosphate binding(GO:0030976)
0.0 0.2 GO:0016918 retinal binding(GO:0016918) retinol binding(GO:0019841)
0.0 0.8 GO:0008408 3'-5' exonuclease activity(GO:0008408)
0.0 0.8 GO:0017080 sodium channel regulator activity(GO:0017080)
0.0 0.4 GO:0050840 extracellular matrix binding(GO:0050840)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 6.3 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.2 10.2 ST JNK MAPK PATHWAY JNK MAPK Pathway
0.1 16.9 PID E2F PATHWAY E2F transcription factor network
0.1 5.4 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.1 0.6 ST IL 13 PATHWAY Interleukin 13 (IL-13) Pathway
0.1 0.7 SA G1 AND S PHASES Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.1 2.1 PID NFKAPPAB ATYPICAL PATHWAY Atypical NF-kappaB pathway
0.1 4.4 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.1 4.2 PID P75 NTR PATHWAY p75(NTR)-mediated signaling
0.1 1.5 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.1 3.9 PID IL12 2PATHWAY IL12-mediated signaling events
0.0 2.3 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.0 2.2 PID BMP PATHWAY BMP receptor signaling
0.0 1.2 PID ARF6 PATHWAY Arf6 signaling events
0.0 6.2 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 2.5 PID LYSOPHOSPHOLIPID PATHWAY LPA receptor mediated events
0.0 0.5 PID ARF 3PATHWAY Arf1 pathway
0.0 0.8 PID FOXO PATHWAY FoxO family signaling
0.0 0.5 PID NETRIN PATHWAY Netrin-mediated signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
13.5 40.5 REACTOME XENOBIOTICS Genes involved in Xenobiotics
2.4 33.1 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
1.2 16.9 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.6 25.5 REACTOME STEROID HORMONES Genes involved in Steroid hormones
0.4 7.2 REACTOME PYRIMIDINE CATABOLISM Genes involved in Pyrimidine catabolism
0.3 2.5 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.2 8.7 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.2 3.4 REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.2 7.8 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.2 11.5 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.2 14.1 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.2 5.9 REACTOME SHC1 EVENTS IN EGFR SIGNALING Genes involved in SHC1 events in EGFR signaling
0.1 2.9 REACTOME LIGAND GATED ION CHANNEL TRANSPORT Genes involved in Ligand-gated ion channel transport
0.1 1.1 REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1 Genes involved in IKK complex recruitment mediated by RIP1
0.1 13.7 REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES Genes involved in Metabolism of amino acids and derivatives
0.1 3.5 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.1 0.9 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.0 0.7 REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane
0.0 2.5 REACTOME MEIOTIC SYNAPSIS Genes involved in Meiotic Synapsis
0.0 2.4 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.0 1.3 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.0 2.5 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.0 0.8 REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS Genes involved in Trafficking of GluR2-containing AMPA receptors
0.0 0.4 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.0 0.6 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GLP1 Genes involved in Synthesis, Secretion, and Inactivation of Glucagon-like Peptide-1 (GLP-1)
0.0 0.3 REACTOME ACYL CHAIN REMODELLING OF PS Genes involved in Acyl chain remodelling of PS
0.0 0.8 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 0.4 REACTOME PHOSPHORYLATION OF THE APC C Genes involved in Phosphorylation of the APC/C
0.0 0.5 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.0 1.0 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 0.3 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions