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GSE58827: Dynamics of the Mouse Liver

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Results for Fos

Z-value: 2.03

Motif logo

Transcription factors associated with Fos

Gene Symbol Gene ID Gene Info
ENSMUSG00000021250.14 FBJ osteosarcoma oncogene

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Fosmm39_v1_chr12_+_85520652_855206720.633.9e-05Click!

Activity profile of Fos motif

Sorted Z-values of Fos motif

Promoter Log-likelihood Transcript Gene Gene Info
chr11_-_102255999 34.45 ENSMUST00000006749.10
solute carrier family 4 (anion exchanger), member 1
chr7_-_45570254 28.21 ENSMUST00000164119.3
epithelial membrane protein 3
chr7_-_45570538 27.83 ENSMUST00000210297.2
epithelial membrane protein 3
chr1_-_132318039 26.00 ENSMUST00000132435.2
transmembrane and coiled-coil domains 2
chr7_+_24069680 22.80 ENSMUST00000205428.2
ENSMUST00000171904.3
ENSMUST00000205626.2
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 4
chr3_-_88410495 20.73 ENSMUST00000120377.8
ENSMUST00000029699.13
lamin A
chr7_-_45570674 16.34 ENSMUST00000210939.2
epithelial membrane protein 3
chr2_+_164790139 16.02 ENSMUST00000017881.3
matrix metallopeptidase 9
chr7_+_78563964 15.90 ENSMUST00000120331.4
interferon-stimulated protein
chr2_+_13578738 15.59 ENSMUST00000141365.3
ENSMUST00000028062.8
vimentin
chr8_+_95710977 15.49 ENSMUST00000093271.8
adhesion G protein-coupled receptor G1
chr7_+_78563513 15.20 ENSMUST00000038142.15
interferon-stimulated protein
chr7_-_126398343 14.23 ENSMUST00000032934.12
aldolase A, fructose-bisphosphate
chr2_+_84564394 14.09 ENSMUST00000238573.2
ENSMUST00000090729.9
yippee like 4
chr10_+_128745214 13.84 ENSMUST00000220308.2
CD63 antigen
chr7_-_125968653 13.78 ENSMUST00000205642.2
ENSMUST00000032997.8
ENSMUST00000206793.2
linker for activation of T cells
chr7_-_126398165 13.57 ENSMUST00000205890.2
ENSMUST00000205336.2
ENSMUST00000087566.11
aldolase A, fructose-bisphosphate
chrX_-_7537580 13.20 ENSMUST00000033486.6
proteolipid protein 2
chr1_+_174000304 13.12 ENSMUST00000027817.8
spectrin alpha, erythrocytic 1
chr7_-_143056252 12.91 ENSMUST00000010904.5
pleckstrin homology like domain, family A, member 2
chr7_+_78564062 12.41 ENSMUST00000205981.2
interferon-stimulated protein
chrX_-_142610371 12.14 ENSMUST00000087316.6
calpain 6
chr13_+_95833359 11.23 ENSMUST00000022182.5
coagulation factor II (thrombin) receptor-like 2
chr7_+_110371811 11.21 ENSMUST00000005829.13
adenosine monophosphate deaminase 3
chr9_+_51124983 10.77 ENSMUST00000034554.9
POU domain, class 2, associating factor 1
chrX_-_133483849 10.70 ENSMUST00000113213.2
ENSMUST00000033617.13
Bruton agammaglobulinemia tyrosine kinase
chr2_+_24226857 10.15 ENSMUST00000114487.9
ENSMUST00000142093.7
interleukin 1 receptor antagonist
chr4_-_43558386 9.87 ENSMUST00000130353.2
talin 1
chr14_-_54949596 9.64 ENSMUST00000064290.8
CCAAT/enhancer binding protein (C/EBP), epsilon
chr4_-_43040278 9.58 ENSMUST00000107958.8
ENSMUST00000107959.8
ENSMUST00000152846.8
family with sequence similarity 214, member B
chr4_-_140501507 9.53 ENSMUST00000026381.7
peptidyl arginine deiminase, type IV
chr9_+_69360902 9.44 ENSMUST00000034756.15
ENSMUST00000123470.8
annexin A2
chr7_+_18817767 9.32 ENSMUST00000032568.14
ENSMUST00000122999.8
ENSMUST00000108473.10
ENSMUST00000108474.2
ENSMUST00000238982.2
dystrophia myotonica-protein kinase
chr12_+_103354915 9.26 ENSMUST00000101094.9
ENSMUST00000021620.13
OTU domain, ubiquitin aldehyde binding 2
chr6_+_135339543 9.08 ENSMUST00000205156.3
epithelial membrane protein 1
chr17_+_35268942 8.96 ENSMUST00000007257.10
chloride intracellular channel 1
chr9_+_69361348 8.72 ENSMUST00000134907.8
annexin A2
chr8_+_94954280 8.40 ENSMUST00000109547.2
nucleoporin 93
chr3_+_95836558 7.96 ENSMUST00000165307.8
ENSMUST00000015893.13
ENSMUST00000169426.8
acidic (leucine-rich) nuclear phosphoprotein 32 family, member E
chr1_+_172328768 7.85 ENSMUST00000111228.2
transgelin 2
chr17_+_46471950 7.50 ENSMUST00000024748.14
ENSMUST00000172170.8
GTP binding protein 2
chr8_+_123008855 7.49 ENSMUST00000054052.15
zinc finger protein, multitype 1
chr11_+_116422712 7.37 ENSMUST00000100201.10
sphingosine kinase 1
chr11_+_116422570 7.36 ENSMUST00000106387.9
sphingosine kinase 1
chr10_+_111309020 7.25 ENSMUST00000065917.16
ENSMUST00000219961.2
ENSMUST00000217908.2
nucleosome assembly protein 1-like 1
chr3_+_95836637 7.19 ENSMUST00000171368.8
ENSMUST00000168106.8
acidic (leucine-rich) nuclear phosphoprotein 32 family, member E
chr10_+_111309127 6.98 ENSMUST00000219143.2
nucleosome assembly protein 1-like 1
chrX_-_47543029 6.98 ENSMUST00000114958.8
E74-like factor 4 (ets domain transcription factor)
chr11_+_116424082 6.94 ENSMUST00000154034.8
sphingosine kinase 1
chr1_-_59012579 6.67 ENSMUST00000173590.2
ENSMUST00000027186.12
trafficking protein, kinesin binding 2
chr14_+_79753055 6.65 ENSMUST00000110835.3
ENSMUST00000227192.2
E74-like factor 1
chrX_-_165992311 6.51 ENSMUST00000112172.4
thymosin, beta 4, X chromosome
chr6_+_135339929 6.43 ENSMUST00000032330.16
epithelial membrane protein 1
chr3_+_95139598 6.28 ENSMUST00000107200.8
ENSMUST00000107199.2
CDC42 small effector 1
chr5_+_35156389 6.27 ENSMUST00000114281.8
ENSMUST00000114280.8
regulator of G-protein signaling 12
chr14_-_32907023 6.20 ENSMUST00000130509.10
ENSMUST00000061753.15
WD repeat and FYVE domain containing 4
chr10_+_79762858 6.19 ENSMUST00000019708.12
ENSMUST00000105377.8
AT rich interactive domain 3A (BRIGHT-like)
chr8_+_95711037 6.08 ENSMUST00000211944.2
adhesion G protein-coupled receptor G1
chrX_-_165992145 6.04 ENSMUST00000112176.8
thymosin, beta 4, X chromosome
chr6_+_42326760 6.02 ENSMUST00000203652.3
ENSMUST00000070635.13
zyxin
chr6_+_42326934 5.96 ENSMUST00000203401.3
ENSMUST00000164375.4
zyxin
chr7_-_19005721 5.92 ENSMUST00000032561.9
vasodilator-stimulated phosphoprotein
chr6_-_113411718 5.86 ENSMUST00000113091.8
cell death-inducing DFFA-like effector c
chr17_+_12338161 5.84 ENSMUST00000024594.9
1-acylglycerol-3-phosphate O-acyltransferase 4 (lysophosphatidic acid acyltransferase, delta)
chr6_+_42326714 5.78 ENSMUST00000203846.3
zyxin
chr5_+_100993996 5.72 ENSMUST00000112887.8
ENSMUST00000031255.15
glycerol-3-phosphate acyltransferase 3
chr11_-_53371050 5.70 ENSMUST00000104955.4
sosondowah ankyrin repeat domain family member A
chr5_+_25452342 5.70 ENSMUST00000114950.2
polypeptide N-acetylgalactosaminyltransferase 11
chr17_-_57501170 5.70 ENSMUST00000005976.8
tumor necrosis factor (ligand) superfamily, member 14
chr17_+_29170924 5.68 ENSMUST00000153462.8
potassium channel tetramerisation domain containing 20
chr7_+_27186335 5.61 ENSMUST00000008528.8
SERTA domain containing 1
chr15_-_64184485 5.60 ENSMUST00000177083.8
ENSMUST00000177371.8
ArfGAP with SH3 domain, ankyrin repeat and PH domain1
chr18_+_82928959 5.58 ENSMUST00000171238.8
zinc finger protein 516
chr10_+_80765900 5.49 ENSMUST00000015456.10
ENSMUST00000220246.2
growth arrest and DNA-damage-inducible 45 beta
chr11_+_78079243 5.31 ENSMUST00000002128.14
ENSMUST00000150941.8
RAB34, member RAS oncogene family
chr5_-_134975773 5.28 ENSMUST00000051401.4
claudin 4
chr17_+_29171655 5.27 ENSMUST00000117672.9
ENSMUST00000153831.9
potassium channel tetramerisation domain containing 20
chr2_-_113883285 5.26 ENSMUST00000090269.7
actin, alpha, cardiac muscle 1
chr2_+_30331839 5.20 ENSMUST00000131476.8
protein phosphatase 2 protein activator
chr11_+_61575245 5.03 ENSMUST00000093019.6
family with sequence similarity 83, member G
chr8_+_89015705 4.95 ENSMUST00000171456.9
adenylate cyclase 7
chr17_-_7652863 4.90 ENSMUST00000070059.5
unc-93 homolog A2
chr3_-_10273628 4.87 ENSMUST00000029041.6
fatty acid binding protein 4, adipocyte
chr10_+_80100812 4.84 ENSMUST00000105362.8
ENSMUST00000105361.10
DAZ associated protein 1
chr11_+_78079631 4.79 ENSMUST00000056241.12
ENSMUST00000207728.2
RAB34, member RAS oncogene family
chr4_+_132857816 4.52 ENSMUST00000084241.12
ENSMUST00000138831.2
WASP family, member 2
chr5_+_100994230 4.48 ENSMUST00000092990.4
ENSMUST00000145612.2
glycerol-3-phosphate acyltransferase 3
chr4_-_6454262 4.36 ENSMUST00000029910.12
neutral sphingomyelinase (N-SMase) activation associated factor
chr14_-_70415117 4.21 ENSMUST00000022681.11
PDZ and LIM domain 2
chr7_-_30741532 4.21 ENSMUST00000160689.8
ENSMUST00000202395.4
ENSMUST00000162733.8
ENSMUST00000162087.8
ENSMUST00000009831.14
FXYD domain-containing ion transport regulator 5
chr2_-_25086810 4.21 ENSMUST00000081869.7
torsin family 4, member A
chr16_+_35590745 4.18 ENSMUST00000231579.2
Hspb associated protein 1
chr12_+_111505216 4.14 ENSMUST00000050993.11
eukaryotic translation initiation factor 5
chr12_+_111505253 4.10 ENSMUST00000220803.2
eukaryotic translation initiation factor 5
chr11_-_78950641 4.06 ENSMUST00000226282.2
kinase suppressor of ras 1
chr18_-_38131766 4.05 ENSMUST00000236588.2
ENSMUST00000237272.2
ENSMUST00000236134.2
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3
chr3_+_103009920 4.04 ENSMUST00000173206.8
DENN/MADD domain containing 2C
chr15_-_90563510 3.98 ENSMUST00000014777.9
ENSMUST00000064391.12
copine VIII
chr4_+_43506966 3.91 ENSMUST00000030183.10
carbonic anhydrase 9
chr7_+_126376353 3.90 ENSMUST00000106356.2
yippee like 3
chr7_-_105131407 3.86 ENSMUST00000047040.4
caveolae associated 3
chr6_+_42326980 3.85 ENSMUST00000203849.2
zyxin
chr3_+_14706781 3.77 ENSMUST00000029071.9
carbonic anhydrase 13
chr12_+_31315270 3.73 ENSMUST00000002979.16
ENSMUST00000239496.2
ENSMUST00000170495.3
laminin B1
chrX_-_100266032 3.71 ENSMUST00000120389.8
ENSMUST00000156473.8
ENSMUST00000077876.4
sorting nexin 12
chr15_+_84553801 3.66 ENSMUST00000171460.8
proline rich 5 (renal)
chrX_+_95498965 3.61 ENSMUST00000033553.14
hephaestin
chr5_+_35156454 3.53 ENSMUST00000114283.8
regulator of G-protein signaling 12
chr7_-_30741497 3.52 ENSMUST00000162116.8
ENSMUST00000159924.8
FXYD domain-containing ion transport regulator 5
chr9_-_78388080 3.50 ENSMUST00000156988.2
eukaryotic translation elongation factor 1 alpha 1
chr8_-_25581354 3.49 ENSMUST00000125466.2
pleckstrin homology domain-containing, family A (phosphoinositide binding specific) member 2
chrX_+_158623460 3.38 ENSMUST00000112451.8
ENSMUST00000112453.9
SH3-domain kinase binding protein 1
chr6_+_42326528 3.28 ENSMUST00000203329.3
zyxin
chr19_-_34143437 3.28 ENSMUST00000025686.9
ankyrin repeat domain 22
chr7_+_126184108 3.28 ENSMUST00000039522.8
apolipoprotein B receptor
chr4_-_3835595 3.27 ENSMUST00000138502.2
ribosomal protein S20
chr1_-_52230062 3.19 ENSMUST00000156887.8
ENSMUST00000129107.2
glutaminase
chr2_-_101627999 3.16 ENSMUST00000171088.8
ENSMUST00000043845.14
proline rich 5 like
chr10_+_97318223 3.11 ENSMUST00000163448.4
decorin
chr10_-_76562002 3.11 ENSMUST00000001147.5
collagen, type VI, alpha 1
chr13_-_21964747 3.03 ENSMUST00000080511.3
H1.5 linker histone, cluster member
chr3_-_122828592 3.00 ENSMUST00000029761.14
myozenin 2
chr2_-_25086770 2.99 ENSMUST00000142857.2
ENSMUST00000137920.2
torsin family 4, member A
chr1_-_153061758 2.96 ENSMUST00000185356.7
laminin, gamma 2
chr1_+_107439145 2.95 ENSMUST00000009356.11
ENSMUST00000064916.9
serine (or cysteine) peptidase inhibitor, clade B, member 2
chr11_-_76400245 2.95 ENSMUST00000094012.11
active BCR-related gene
chr2_-_25114660 2.93 ENSMUST00000043584.5
tubulin, beta 4B class IVB
chr11_+_78079562 2.92 ENSMUST00000108322.9
RAB34, member RAS oncogene family
chr10_+_79763164 2.92 ENSMUST00000105376.2
AT rich interactive domain 3A (BRIGHT-like)
chr2_-_44817173 2.92 ENSMUST00000130991.8
glycosyltransferase-like domain containing 1
chr1_+_40554513 2.90 ENSMUST00000027237.12
interleukin 18 receptor accessory protein
chr7_-_30741237 2.90 ENSMUST00000161805.8
FXYD domain-containing ion transport regulator 5
chr10_+_94386714 2.89 ENSMUST00000148910.3
ENSMUST00000117460.8
transmembrane and coiled coil domains 3
chr14_+_25459690 2.86 ENSMUST00000007961.15
zinc finger, MIZ-type containing 1
chr7_-_101899294 2.80 ENSMUST00000106923.2
ENSMUST00000098230.11
ras homolog family member G
chr17_+_36152383 2.76 ENSMUST00000082337.13
mediator of DNA damage checkpoint 1
chr17_-_48145466 2.76 ENSMUST00000066368.13
MyoD family inhibitor
chr9_+_107879700 2.71 ENSMUST00000035214.11
ENSMUST00000176854.7
ENSMUST00000175874.2
inositol hexaphosphate kinase 1
chr10_+_128247598 2.71 ENSMUST00000096386.13
ring finger protein 41
chr12_+_31315227 2.69 ENSMUST00000169088.8
laminin B1
chr11_-_100098333 2.67 ENSMUST00000007272.8
keratin 14
chr19_-_32188413 2.67 ENSMUST00000151289.9
sphingomyelin synthase 1
chr18_-_43610829 2.67 ENSMUST00000057110.11
eukaryotic translation initiation factor 3, subunit J2
chr17_-_45883421 2.67 ENSMUST00000130406.2
heat shock protein 90 alpha (cytosolic), class B member 1
chr9_-_71803354 2.62 ENSMUST00000184448.8
transcription factor 12
chr18_+_23885390 2.60 ENSMUST00000170802.8
ENSMUST00000155708.8
ENSMUST00000118826.9
microtubule-associated protein, RP/EB family, member 2
chr10_+_128247492 2.60 ENSMUST00000171342.3
ring finger protein 41
chr7_+_30450896 2.59 ENSMUST00000182229.8
ENSMUST00000080518.14
ENSMUST00000182227.8
ENSMUST00000182721.8
suprabasin
chr13_-_99027482 2.58 ENSMUST00000179301.8
ENSMUST00000179271.2
transportin 1
chr13_-_63006176 2.58 ENSMUST00000021907.9
fructose bisphosphatase 2
chr10_+_127126643 2.57 ENSMUST00000026475.15
ENSMUST00000139091.2
ENSMUST00000230446.2
DNA-damage inducible transcript 3
DNA-damage inducible transcript 3
chr9_-_116004386 2.56 ENSMUST00000035014.8
transforming growth factor, beta receptor II
chr11_+_20493306 2.54 ENSMUST00000093292.11
SERTA domain containing 2
chr3_-_95139472 2.54 ENSMUST00000196025.5
ENSMUST00000198948.5
myeloid/lymphoid or mixed-lineage leukemia; translocated to, 11
chr19_+_29229147 2.51 ENSMUST00000025705.7
ENSMUST00000065796.10
ENSMUST00000236990.2
Janus kinase 2
chrX_-_103714653 2.50 ENSMUST00000042070.6
zinc finger, DHHC domain containing 15
chr2_+_155593030 2.49 ENSMUST00000029140.12
ENSMUST00000132608.2
protein C receptor, endothelial
chr4_-_6454097 2.48 ENSMUST00000124344.2
neutral sphingomyelinase (N-SMase) activation associated factor
chr3_+_88528743 2.47 ENSMUST00000170653.9
ENSMUST00000177303.8
rho/rac guanine nucleotide exchange factor (GEF) 2
chr5_+_105563605 2.45 ENSMUST00000112707.3
leucine rich repeat containing 8 family, member B
chrX_+_71006577 2.45 ENSMUST00000048790.7
proline rich Gla (G-carboxyglutamic acid) 3 (transmembrane)
chr16_-_44379226 2.45 ENSMUST00000114634.3
biregional cell adhesion molecule-related/down-regulated by oncogenes (Cdon) binding protein
chr8_-_61407760 2.43 ENSMUST00000110302.8
chloride channel, voltage-sensitive 3
chr6_-_71609635 2.42 ENSMUST00000167220.4
ENSMUST00000205289.2
lysine (K)-specific demethylase 3A
chr14_-_30909082 2.40 ENSMUST00000170253.8
nischarin
chr14_+_25459630 2.39 ENSMUST00000162645.8
zinc finger, MIZ-type containing 1
chr18_+_44204457 2.38 ENSMUST00000068473.4
ENSMUST00000236634.2
serine peptidase inhibitor, Kazal type 6
chr14_-_86986541 2.32 ENSMUST00000226254.2
diaphanous related formin 3
chr18_-_70186503 2.27 ENSMUST00000117692.8
ENSMUST00000069749.9
RAB27B, member RAS oncogene family
chr7_+_127728712 2.26 ENSMUST00000033053.8
ENSMUST00000205460.2
integrin alpha X
chr11_-_74615496 2.24 ENSMUST00000021091.15
platelet-activating factor acetylhydrolase, isoform 1b, subunit 1
chr7_+_126376099 2.24 ENSMUST00000038614.12
ENSMUST00000170882.8
ENSMUST00000106359.2
ENSMUST00000106357.8
ENSMUST00000145762.8
yippee like 3
chr11_+_116324913 2.22 ENSMUST00000057676.7
UBA-like domain containing 2
chr2_-_70655997 2.19 ENSMUST00000038584.9
tousled-like kinase 1
chr9_+_117888124 2.16 ENSMUST00000123690.2
5-azacytidine induced gene 2
chr7_-_141925947 2.15 ENSMUST00000084412.6
interferon induced transmembrane protein 10
chr11_-_69556888 2.14 ENSMUST00000108654.3
CD68 antigen
chr15_-_58695379 2.14 ENSMUST00000072113.6
transmembrane protein 65
chr4_-_133329479 2.12 ENSMUST00000057311.4
stratifin
chr11_-_86648309 2.11 ENSMUST00000060766.16
ENSMUST00000103186.11
clathrin, heavy polypeptide (Hc)
chr6_-_113411489 2.10 ENSMUST00000133348.2
cell death-inducing DFFA-like effector c
chr15_-_38518406 2.09 ENSMUST00000151319.8
antizyme inhibitor 1
chr11_-_69556904 2.09 ENSMUST00000018918.12
CD68 antigen
chr7_-_30741512 2.06 ENSMUST00000159753.2
FXYD domain-containing ion transport regulator 5
chr9_-_57168777 2.06 ENSMUST00000217657.2
RIKEN cDNA 1700017B05 gene
chr2_-_102282844 2.04 ENSMUST00000099678.5
four jointed box 1
chr10_-_79369584 2.00 ENSMUST00000218241.2
ENSMUST00000166804.2
ENSMUST00000063879.13
phospholipid phosphatase 2
chr1_-_182345011 1.96 ENSMUST00000068505.10
calpain 2
chr3_-_92393193 1.92 ENSMUST00000054599.8
small proline-rich protein 1A
chr12_-_84240781 1.90 ENSMUST00000110294.2
mitotic deacetylase associated SANT domain protein
chr12_+_83678987 1.90 ENSMUST00000048155.16
ENSMUST00000182618.8
ENSMUST00000183154.8
ENSMUST00000182036.8
ENSMUST00000182347.8
RNA binding motif protein 25
chrX_-_7606445 1.89 ENSMUST00000128289.8
coiled-coil domain containing 120
chr6_+_49013517 1.87 ENSMUST00000031840.10
glycoprotein (transmembrane) nmb
chr14_-_32907446 1.81 ENSMUST00000159606.2
WD repeat and FYVE domain containing 4
chr7_+_120516967 1.81 ENSMUST00000207481.2
ENSMUST00000106483.4
ENSMUST00000033173.15
polymerase (RNA) III (DNA directed) polypeptide E
chr5_-_5315968 1.79 ENSMUST00000115451.8
ENSMUST00000115452.8
ENSMUST00000131392.8
cyclin-dependent kinase 14
chr11_+_80274105 1.69 ENSMUST00000165565.8
ENSMUST00000188489.7
ENSMUST00000017567.14
ENSMUST00000108216.8
ENSMUST00000053740.15
zinc finger protein 207
chr5_-_24597009 1.59 ENSMUST00000059401.7
autophagy related 9B
chr2_+_26481435 1.58 ENSMUST00000152988.9
ENSMUST00000149789.2
EGF-like domain 7
chr17_+_75485791 1.56 ENSMUST00000135447.8
ENSMUST00000112516.8
latent transforming growth factor beta binding protein 1

Network of associatons between targets according to the STRING database.

First level regulatory network of Fos

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
7.3 43.5 GO:0000738 DNA catabolic process, exonucleolytic(GO:0000738)
5.3 16.0 GO:0071460 cellular response to cell-matrix adhesion(GO:0071460)
3.8 11.3 GO:0060722 spongiotrophoblast cell proliferation(GO:0060720) cell proliferation involved in embryonic placenta development(GO:0060722)
3.6 10.7 GO:0002344 peripheral B cell selection(GO:0002343) B cell affinity maturation(GO:0002344)
3.5 20.7 GO:0030951 establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951)
3.1 21.7 GO:0019371 cyclooxygenase pathway(GO:0019371)
2.8 87.9 GO:0032060 bleb assembly(GO:0032060)
2.7 18.7 GO:0052205 modulation of molecular function in other organism(GO:0044359) negative regulation of molecular function in other organism(GO:0044362) negative regulation of molecular function in other organism involved in symbiotic interaction(GO:0052204) modulation of molecular function in other organism involved in symbiotic interaction(GO:0052205) negative regulation by host of symbiont molecular function(GO:0052405) modification by host of symbiont molecular function(GO:0052428)
2.6 13.0 GO:1905169 protein localization to phagocytic vesicle(GO:1905161) regulation of protein localization to phagocytic vesicle(GO:1905169) positive regulation of protein localization to phagocytic vesicle(GO:1905171)
2.3 13.8 GO:2000680 regulation of rubidium ion transport(GO:2000680)
2.2 10.8 GO:2000660 negative regulation of interleukin-1-mediated signaling pathway(GO:2000660)
2.0 9.8 GO:0038032 termination of G-protein coupled receptor signaling pathway(GO:0038032)
1.9 15.6 GO:1900147 Schwann cell migration(GO:0036135) regulation of Schwann cell migration(GO:1900147)
1.9 9.5 GO:0036414 protein citrullination(GO:0018101) histone citrullination(GO:0036414)
1.9 5.7 GO:0008588 release of cytoplasmic sequestered NF-kappaB(GO:0008588)
1.9 7.5 GO:0042097 interleukin-4 biosynthetic process(GO:0042097) regulation of interleukin-4 biosynthetic process(GO:0045402)
1.7 5.2 GO:0030472 mitotic spindle organization in nucleus(GO:0030472)
1.7 8.5 GO:0014722 regulation of skeletal muscle contraction by calcium ion signaling(GO:0014722)
1.7 30.4 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
1.6 6.4 GO:0021812 neuronal-glial interaction involved in cerebral cortex radial glia guided migration(GO:0021812)
1.5 7.5 GO:0070966 nuclear-transcribed mRNA catabolic process, no-go decay(GO:0070966)
1.5 23.7 GO:0050862 positive regulation of T cell receptor signaling pathway(GO:0050862)
1.4 8.4 GO:0090521 glomerular visceral epithelial cell migration(GO:0090521)
1.4 2.8 GO:0002649 regulation of tolerance induction to self antigen(GO:0002649)
1.3 3.9 GO:0036363 transforming growth factor beta activation(GO:0036363)
1.3 3.9 GO:1901003 negative regulation of fermentation(GO:1901003)
1.2 3.7 GO:2000642 negative regulation of early endosome to late endosome transport(GO:2000642)
1.1 11.2 GO:0032261 purine nucleotide salvage(GO:0032261) IMP salvage(GO:0032264)
1.0 27.6 GO:0015701 bicarbonate transport(GO:0015701)
0.9 21.6 GO:0021796 cerebral cortex regionalization(GO:0021796)
0.8 2.5 GO:0071349 interleukin-12-mediated signaling pathway(GO:0035722) cellular response to interleukin-12(GO:0071349)
0.8 2.4 GO:0097401 synaptic vesicle lumen acidification(GO:0097401)
0.8 5.6 GO:1903527 positive regulation of membrane tubulation(GO:1903527)
0.8 6.9 GO:0038203 TORC2 signaling(GO:0038203)
0.7 12.6 GO:0051152 positive regulation of smooth muscle cell differentiation(GO:0051152)
0.7 13.8 GO:0006968 cellular defense response(GO:0006968)
0.7 5.7 GO:0018243 protein O-linked glycosylation via threonine(GO:0018243)
0.7 2.1 GO:0010482 epidermal cell division(GO:0010481) regulation of epidermal cell division(GO:0010482)
0.7 2.1 GO:1900126 negative regulation of hyaluronan biosynthetic process(GO:1900126)
0.7 9.9 GO:0007016 cytoskeletal anchoring at plasma membrane(GO:0007016)
0.7 6.7 GO:0098937 dendritic transport(GO:0098935) anterograde dendritic transport(GO:0098937)
0.7 5.3 GO:1901525 negative regulation of macromitophagy(GO:1901525)
0.7 9.9 GO:0035871 protein K11-linked deubiquitination(GO:0035871)
0.6 2.6 GO:2000016 negative regulation of determination of dorsal identity(GO:2000016)
0.6 15.1 GO:0043486 histone exchange(GO:0043486)
0.6 3.3 GO:0007296 vitellogenesis(GO:0007296)
0.5 9.1 GO:0001731 formation of translation preinitiation complex(GO:0001731)
0.5 3.2 GO:0006543 glutamine catabolic process(GO:0006543)
0.5 2.1 GO:1902269 positive regulation of polyamine transmembrane transport(GO:1902269)
0.5 4.6 GO:0030240 skeletal muscle thin filament assembly(GO:0030240)
0.4 1.3 GO:0046005 positive regulation of circadian sleep/wake cycle, REM sleep(GO:0046005)
0.4 1.8 GO:0007290 spermatid nucleus elongation(GO:0007290)
0.4 5.7 GO:0051901 positive regulation of mitochondrial depolarization(GO:0051901)
0.4 2.2 GO:0044565 dendritic cell proliferation(GO:0044565)
0.4 4.1 GO:0035021 negative regulation of Rac protein signal transduction(GO:0035021)
0.4 5.5 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.4 2.2 GO:0051661 maintenance of centrosome location(GO:0051661)
0.4 2.9 GO:0060313 negative regulation of neutrophil degranulation(GO:0043314) negative regulation of blood vessel remodeling(GO:0060313)
0.4 11.2 GO:0051482 positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway(GO:0051482)
0.3 2.3 GO:0071985 multivesicular body sorting pathway(GO:0071985)
0.3 8.0 GO:0034389 lipid particle organization(GO:0034389)
0.3 3.5 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.3 2.5 GO:0071802 negative regulation of podosome assembly(GO:0071802)
0.3 13.1 GO:0006779 porphyrin-containing compound biosynthetic process(GO:0006779)
0.3 1.2 GO:0042660 positive regulation of cell fate specification(GO:0042660) regulation of interleukin-6-mediated signaling pathway(GO:0070103)
0.3 4.4 GO:0071361 cellular response to ethanol(GO:0071361)
0.3 0.8 GO:0003430 growth plate cartilage chondrocyte growth(GO:0003430)
0.3 3.2 GO:0001866 NK T cell proliferation(GO:0001866)
0.3 1.3 GO:1902340 telomeric heterochromatin assembly(GO:0031509) negative regulation of chromosome condensation(GO:1902340)
0.3 4.9 GO:0071285 cellular response to lithium ion(GO:0071285)
0.2 2.1 GO:0090343 positive regulation of cell aging(GO:0090343) positive regulation of cellular senescence(GO:2000774)
0.2 1.6 GO:0045110 intermediate filament bundle assembly(GO:0045110)
0.2 2.7 GO:0006020 inositol metabolic process(GO:0006020)
0.2 2.2 GO:0001672 regulation of chromatin assembly or disassembly(GO:0001672)
0.2 2.4 GO:1900004 regulation of serine-type endopeptidase activity(GO:1900003) negative regulation of serine-type endopeptidase activity(GO:1900004) regulation of serine-type peptidase activity(GO:1902571) negative regulation of serine-type peptidase activity(GO:1902572)
0.2 1.6 GO:0044805 late nucleophagy(GO:0044805)
0.2 1.0 GO:0035092 sperm chromatin condensation(GO:0035092)
0.2 0.5 GO:0035441 cell migration involved in vasculogenesis(GO:0035441)
0.2 9.7 GO:1902476 chloride transmembrane transport(GO:1902476)
0.2 1.0 GO:0048840 otolith development(GO:0048840)
0.2 1.0 GO:1900245 positive regulation of MDA-5 signaling pathway(GO:1900245)
0.2 3.0 GO:0070831 basement membrane assembly(GO:0070831)
0.2 5.3 GO:0035855 megakaryocyte development(GO:0035855)
0.1 2.7 GO:0002862 negative regulation of inflammatory response to antigenic stimulus(GO:0002862)
0.1 7.7 GO:0006730 one-carbon metabolic process(GO:0006730)
0.1 2.5 GO:0016188 synaptic vesicle maturation(GO:0016188)
0.1 1.1 GO:1903912 negative regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation(GO:1903912)
0.1 0.5 GO:0061153 trachea submucosa development(GO:0061152) trachea gland development(GO:0061153)
0.1 4.8 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.1 8.9 GO:0006334 nucleosome assembly(GO:0006334)
0.1 0.6 GO:0038128 ERBB2 signaling pathway(GO:0038128)
0.1 7.3 GO:0019432 triglyceride biosynthetic process(GO:0019432)
0.1 18.2 GO:0007229 integrin-mediated signaling pathway(GO:0007229)
0.1 1.4 GO:0030948 negative regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030948)
0.1 3.6 GO:0006825 copper ion transport(GO:0006825)
0.1 0.6 GO:0035660 MyD88-dependent toll-like receptor 4 signaling pathway(GO:0035660)
0.1 2.0 GO:0016540 protein autoprocessing(GO:0016540)
0.1 6.3 GO:0046329 negative regulation of JNK cascade(GO:0046329)
0.1 1.0 GO:0021506 anterior neuropore closure(GO:0021506) neuropore closure(GO:0021995)
0.1 9.3 GO:2000649 regulation of sodium ion transmembrane transporter activity(GO:2000649)
0.1 3.1 GO:0070208 protein heterotrimerization(GO:0070208)
0.1 5.9 GO:0050873 brown fat cell differentiation(GO:0050873)
0.1 0.2 GO:1902938 regulation of intracellular calcium activated chloride channel activity(GO:1902938)
0.1 12.1 GO:0001578 microtubule bundle formation(GO:0001578)
0.1 2.8 GO:0009950 dorsal/ventral axis specification(GO:0009950)
0.1 0.3 GO:0070782 phosphatidylserine exposure on apoptotic cell surface(GO:0070782)
0.1 2.5 GO:0032967 positive regulation of collagen biosynthetic process(GO:0032967)
0.1 0.4 GO:0016240 autophagosome docking(GO:0016240)
0.1 1.3 GO:0097264 self proteolysis(GO:0097264)
0.1 3.5 GO:0071364 cellular response to epidermal growth factor stimulus(GO:0071364)
0.1 1.0 GO:0007021 tubulin complex assembly(GO:0007021)
0.1 5.8 GO:0042982 amyloid precursor protein metabolic process(GO:0042982)
0.1 1.4 GO:0035025 positive regulation of Rho protein signal transduction(GO:0035025)
0.1 1.3 GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.1 0.9 GO:0043402 glucocorticoid mediated signaling pathway(GO:0043402)
0.1 2.7 GO:0030225 macrophage differentiation(GO:0030225)
0.1 4.8 GO:0019933 cAMP-mediated signaling(GO:0019933)
0.1 0.2 GO:0032329 serine transport(GO:0032329)
0.1 0.2 GO:0051121 hepoxilin metabolic process(GO:0051121) hepoxilin biosynthetic process(GO:0051122)
0.1 0.8 GO:1902260 negative regulation of delayed rectifier potassium channel activity(GO:1902260)
0.1 0.4 GO:0018095 protein polyglutamylation(GO:0018095)
0.1 2.1 GO:1903779 regulation of cardiac conduction(GO:1903779)
0.1 3.3 GO:0032720 negative regulation of tumor necrosis factor production(GO:0032720)
0.1 1.2 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.1 3.3 GO:0001954 positive regulation of cell-matrix adhesion(GO:0001954)
0.1 1.2 GO:0030049 muscle filament sliding(GO:0030049)
0.1 2.5 GO:0045663 positive regulation of myoblast differentiation(GO:0045663)
0.1 2.0 GO:0010842 retina layer formation(GO:0010842)
0.0 0.2 GO:0098886 modification of dendritic spine(GO:0098886)
0.0 0.3 GO:0002729 positive regulation of natural killer cell cytokine production(GO:0002729)
0.0 0.5 GO:0051694 pointed-end actin filament capping(GO:0051694)
0.0 1.3 GO:1902236 negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway(GO:1902236)
0.0 2.8 GO:1903078 positive regulation of protein localization to plasma membrane(GO:1903078)
0.0 0.7 GO:0048245 eosinophil chemotaxis(GO:0048245)
0.0 2.3 GO:0035458 cellular response to interferon-beta(GO:0035458)
0.0 0.5 GO:0070862 negative regulation of protein exit from endoplasmic reticulum(GO:0070862) negative regulation of retrograde protein transport, ER to cytosol(GO:1904153)
0.0 0.1 GO:0002767 immune response-inhibiting signal transduction(GO:0002765) immune response-inhibiting cell surface receptor signaling pathway(GO:0002767)
0.0 4.5 GO:0030838 positive regulation of actin filament polymerization(GO:0030838)
0.0 1.7 GO:0007094 mitotic spindle assembly checkpoint(GO:0007094)
0.0 2.0 GO:0046839 phospholipid dephosphorylation(GO:0046839)
0.0 0.3 GO:0043305 negative regulation of mast cell activation involved in immune response(GO:0033007) negative regulation of mast cell degranulation(GO:0043305)
0.0 0.6 GO:0010880 regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum(GO:0010880)
0.0 2.8 GO:0006641 triglyceride metabolic process(GO:0006641)
0.0 1.9 GO:0030239 myofibril assembly(GO:0030239)
0.0 0.1 GO:0061470 T follicular helper cell differentiation(GO:0061470)
0.0 1.2 GO:0045746 negative regulation of Notch signaling pathway(GO:0045746)
0.0 1.0 GO:0030866 cortical actin cytoskeleton organization(GO:0030866)
0.0 1.9 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.0 0.4 GO:0090557 establishment of endothelial intestinal barrier(GO:0090557)
0.0 0.9 GO:0007099 centriole replication(GO:0007099)
0.0 0.5 GO:0070536 protein K63-linked deubiquitination(GO:0070536)
0.0 0.1 GO:1904936 cerebral cortex GABAergic interneuron migration(GO:0021853) interneuron migration(GO:1904936)
0.0 1.0 GO:0090162 establishment of epithelial cell polarity(GO:0090162)
0.0 0.1 GO:0001915 negative regulation of T cell mediated cytotoxicity(GO:0001915)
0.0 0.1 GO:0070294 renal sodium ion transport(GO:0003096) renal sodium ion absorption(GO:0070294)
0.0 0.9 GO:0060325 face morphogenesis(GO:0060325)
0.0 0.2 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
0.0 0.1 GO:0051798 positive regulation of hair follicle development(GO:0051798)
0.0 0.1 GO:0007406 negative regulation of neuroblast proliferation(GO:0007406)
0.0 1.5 GO:0098656 anion transmembrane transport(GO:0098656)
0.0 1.5 GO:0000086 G2/M transition of mitotic cell cycle(GO:0000086)
0.0 0.5 GO:0050819 negative regulation of coagulation(GO:0050819)
0.0 0.9 GO:0010811 positive regulation of cell-substrate adhesion(GO:0010811)
0.0 0.3 GO:0051281 positive regulation of release of sequestered calcium ion into cytosol(GO:0051281)
0.0 0.6 GO:0055010 ventricular cardiac muscle tissue morphogenesis(GO:0055010)
0.0 0.2 GO:0099514 anterograde synaptic vesicle transport(GO:0048490) synaptic vesicle cytoskeletal transport(GO:0099514) synaptic vesicle transport along microtubule(GO:0099517)
0.0 0.0 GO:0002572 pro-T cell differentiation(GO:0002572)
0.0 1.4 GO:0007030 Golgi organization(GO:0007030)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
6.1 18.2 GO:1990667 PCSK9-AnxA2 complex(GO:1990667)
4.6 13.8 GO:0031904 endosome lumen(GO:0031904)
3.1 9.4 GO:0005607 laminin-2 complex(GO:0005607)
3.0 20.7 GO:0005638 lamin filament(GO:0005638)
2.2 13.1 GO:0032437 cuticular plate(GO:0032437)
2.0 21.6 GO:0097451 glial limiting end-foot(GO:0097451)
1.8 5.3 GO:0042643 actomyosin, actin portion(GO:0042643)
1.4 15.6 GO:0045098 type III intermediate filament(GO:0045098)
1.1 27.8 GO:0035686 sperm fibrous sheath(GO:0035686)
0.9 2.6 GO:1990622 CHOP-C/EBP complex(GO:0036488) CHOP-ATF3 complex(GO:1990622)
0.8 2.5 GO:0038045 large latent transforming growth factor-beta complex(GO:0038045)
0.8 3.9 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
0.7 43.5 GO:0015030 Cajal body(GO:0015030)
0.6 0.6 GO:0014801 longitudinal sarcoplasmic reticulum(GO:0014801)
0.4 6.9 GO:0031932 TORC2 complex(GO:0031932)
0.4 2.3 GO:0032585 multivesicular body membrane(GO:0032585)
0.4 1.8 GO:0000308 cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308)
0.4 2.1 GO:0031523 Myb complex(GO:0031523)
0.3 2.9 GO:0045298 tubulin complex(GO:0045298)
0.3 9.3 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.2 13.9 GO:0008180 COP9 signalosome(GO:0008180)
0.2 3.4 GO:0031209 SCAR complex(GO:0031209)
0.2 29.0 GO:0014704 intercalated disc(GO:0014704)
0.2 2.7 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.2 8.1 GO:0002102 podosome(GO:0002102)
0.2 2.2 GO:0000235 astral microtubule(GO:0000235)
0.2 4.9 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.2 2.7 GO:0000138 Golgi trans cisterna(GO:0000138)
0.2 5.3 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.2 10.0 GO:0005876 spindle microtubule(GO:0005876)
0.2 0.7 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.2 22.4 GO:0097517 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.2 13.7 GO:0045335 phagocytic vesicle(GO:0045335)
0.2 5.3 GO:0071782 endoplasmic reticulum tubular network(GO:0071782)
0.2 5.2 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.1 3.1 GO:0098644 complex of collagen trimers(GO:0098644)
0.1 9.7 GO:0034707 chloride channel complex(GO:0034707)
0.1 0.9 GO:0098536 deuterosome(GO:0098536)
0.1 2.8 GO:0042627 chylomicron(GO:0042627)
0.1 0.4 GO:0097425 smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425)
0.1 1.3 GO:0000788 nuclear nucleosome(GO:0000788)
0.1 1.7 GO:0031143 pseudopodium(GO:0031143)
0.1 1.9 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
0.1 1.0 GO:0098839 postsynaptic density membrane(GO:0098839)
0.1 1.2 GO:0008540 proteasome regulatory particle, base subcomplex(GO:0008540)
0.1 1.3 GO:0008385 IkappaB kinase complex(GO:0008385)
0.1 14.5 GO:0034399 nuclear periphery(GO:0034399)
0.1 1.8 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.1 1.2 GO:0016461 unconventional myosin complex(GO:0016461)
0.1 15.4 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)
0.1 1.1 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.1 2.6 GO:0035371 microtubule plus-end(GO:0035371)
0.1 1.0 GO:0032432 actin filament bundle(GO:0032432)
0.1 3.3 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.1 4.3 GO:0005844 polysome(GO:0005844)
0.1 2.1 GO:0016592 mediator complex(GO:0016592)
0.1 6.7 GO:0005901 caveola(GO:0005901)
0.1 2.5 GO:0044295 axonal growth cone(GO:0044295)
0.1 17.4 GO:0098857 membrane raft(GO:0045121) membrane microdomain(GO:0098857)
0.0 8.6 GO:0001726 ruffle(GO:0001726)
0.0 0.4 GO:0036056 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.0 4.8 GO:0030139 endocytic vesicle(GO:0030139)
0.0 11.3 GO:0008021 synaptic vesicle(GO:0008021)
0.0 4.8 GO:0017053 transcriptional repressor complex(GO:0017053)
0.0 3.2 GO:0030175 filopodium(GO:0030175)
0.0 5.8 GO:0005741 mitochondrial outer membrane(GO:0005741)
0.0 0.3 GO:0008024 cyclin/CDK positive transcription elongation factor complex(GO:0008024)
0.0 0.6 GO:0005861 troponin complex(GO:0005861)
0.0 0.9 GO:0005614 interstitial matrix(GO:0005614)
0.0 2.9 GO:0016605 PML body(GO:0016605)
0.0 14.1 GO:0005789 endoplasmic reticulum membrane(GO:0005789)
0.0 1.4 GO:0031985 Golgi cisterna(GO:0031985)
0.0 0.5 GO:0005771 multivesicular body(GO:0005771)
0.0 0.2 GO:0030123 AP-3 adaptor complex(GO:0030123)
0.0 1.7 GO:0000776 kinetochore(GO:0000776)
0.0 0.1 GO:0071203 WASH complex(GO:0071203)
0.0 0.7 GO:0031519 PcG protein complex(GO:0031519)
0.0 1.5 GO:0030496 midbody(GO:0030496)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
8.7 43.5 GO:0008859 exoribonuclease II activity(GO:0008859)
3.4 10.2 GO:0005152 interleukin-1 receptor antagonist activity(GO:0005152)
2.8 11.2 GO:0015057 thrombin receptor activity(GO:0015057)
2.8 27.8 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
2.5 22.8 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
2.4 21.7 GO:0017050 sphinganine kinase activity(GO:0008481) D-erythro-sphingosine kinase activity(GO:0017050)
2.2 13.5 GO:1990254 keratin filament binding(GO:1990254)
2.0 18.2 GO:0019834 phospholipase A2 inhibitor activity(GO:0019834)
1.9 9.5 GO:0004668 protein-arginine deiminase activity(GO:0004668)
1.7 6.8 GO:0016230 sphingomyelin phosphodiesterase activator activity(GO:0016230)
1.4 31.0 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
1.3 5.3 GO:0005128 erythropoietin receptor binding(GO:0005128)
1.3 9.3 GO:0019784 NEDD8-specific protease activity(GO:0019784)
1.3 5.2 GO:0008160 protein tyrosine phosphatase activator activity(GO:0008160)
1.3 10.2 GO:0004366 glycerol-3-phosphate O-acyltransferase activity(GO:0004366)
1.1 9.1 GO:0071074 eukaryotic initiation factor eIF2 binding(GO:0071074)
1.1 11.2 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.9 2.8 GO:0005026 transforming growth factor beta receptor activity, type II(GO:0005026)
0.8 6.4 GO:0043208 glycosphingolipid binding(GO:0043208)
0.7 3.0 GO:0051373 FATZ binding(GO:0051373)
0.7 9.9 GO:0030274 LIM domain binding(GO:0030274)
0.6 2.5 GO:0050436 microfibril binding(GO:0050436)
0.6 2.4 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
0.6 6.2 GO:0032558 adenyl deoxyribonucleotide binding(GO:0032558)
0.5 3.2 GO:0004359 glutaminase activity(GO:0004359)
0.5 2.1 GO:0042978 ornithine decarboxylase activator activity(GO:0042978)
0.5 14.1 GO:0019956 chemokine binding(GO:0019956)
0.5 2.5 GO:0005143 interleukin-12 receptor binding(GO:0005143)
0.5 13.0 GO:0017160 Ral GTPase binding(GO:0017160)
0.5 20.3 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.5 2.7 GO:0000828 inositol hexakisphosphate kinase activity(GO:0000828) inositol hexakisphosphate 5-kinase activity(GO:0000832) inositol hexakisphosphate 1-kinase activity(GO:0052723) inositol hexakisphosphate 3-kinase activity(GO:0052724)
0.4 16.3 GO:0001968 fibronectin binding(GO:0001968)
0.4 7.7 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.4 15.1 GO:0019212 phosphatase inhibitor activity(GO:0019212)
0.4 1.9 GO:0030280 structural constituent of epidermis(GO:0030280)
0.4 3.3 GO:0045545 syndecan binding(GO:0045545)
0.4 2.8 GO:0030229 very-low-density lipoprotein particle receptor activity(GO:0030229)
0.4 4.9 GO:0004016 adenylate cyclase activity(GO:0004016)
0.3 3.6 GO:0016724 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.3 4.2 GO:0032036 myosin heavy chain binding(GO:0032036)
0.3 4.8 GO:0005522 profilin binding(GO:0005522)
0.3 5.8 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.3 20.6 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.3 16.6 GO:0050840 extracellular matrix binding(GO:0050840)
0.3 8.4 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.3 6.7 GO:0050811 GABA receptor binding(GO:0050811)
0.3 4.8 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.3 2.9 GO:0004908 interleukin-1 receptor activity(GO:0004908)
0.3 2.6 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.3 12.6 GO:0003785 actin monomer binding(GO:0003785)
0.2 1.4 GO:0050816 phosphothreonine binding(GO:0050816)
0.2 7.2 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.2 3.6 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.2 3.6 GO:0035497 cAMP response element binding(GO:0035497)
0.2 4.5 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.2 2.1 GO:0032051 clathrin light chain binding(GO:0032051)
0.2 10.8 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.2 4.1 GO:0035613 RNA stem-loop binding(GO:0035613)
0.2 2.6 GO:0050308 sugar-phosphatase activity(GO:0050308)
0.2 9.8 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.2 1.5 GO:0005225 volume-sensitive anion channel activity(GO:0005225)
0.1 0.3 GO:0005134 interleukin-2 receptor binding(GO:0005134)
0.1 1.0 GO:0030899 calcium-dependent ATPase activity(GO:0030899)
0.1 0.5 GO:0042289 MHC class II protein binding(GO:0042289)
0.1 3.5 GO:0003746 translation elongation factor activity(GO:0003746)
0.1 2.0 GO:0042577 lipid phosphatase activity(GO:0042577)
0.1 0.7 GO:0015111 iodide transmembrane transporter activity(GO:0015111)
0.1 9.4 GO:0017080 sodium channel regulator activity(GO:0017080)
0.1 3.5 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.1 15.9 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979)
0.1 0.9 GO:0043423 3-phosphoinositide-dependent protein kinase binding(GO:0043423)
0.1 1.1 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.1 3.2 GO:0001530 lipopolysaccharide binding(GO:0001530)
0.1 5.7 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.1 0.4 GO:0070740 tubulin-glutamic acid ligase activity(GO:0070740)
0.1 0.3 GO:0004947 bradykinin receptor activity(GO:0004947)
0.1 2.4 GO:0031489 myosin V binding(GO:0031489)
0.1 1.8 GO:0001056 RNA polymerase III activity(GO:0001056)
0.1 4.9 GO:0005504 fatty acid binding(GO:0005504)
0.1 1.0 GO:0005041 low-density lipoprotein receptor activity(GO:0005041)
0.1 1.8 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.1 4.4 GO:0019888 protein phosphatase regulator activity(GO:0019888)
0.1 2.5 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.1 4.0 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.1 0.9 GO:1990380 Lys48-specific deubiquitinase activity(GO:1990380)
0.1 0.7 GO:0005138 interleukin-6 receptor binding(GO:0005138)
0.1 2.2 GO:0070840 dynein complex binding(GO:0070840)
0.1 2.7 GO:0017022 myosin binding(GO:0017022)
0.1 0.3 GO:0034211 GTP-dependent protein kinase activity(GO:0034211)
0.1 1.2 GO:0034236 protein kinase A catalytic subunit binding(GO:0034236)
0.1 1.3 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.1 6.0 GO:0033613 activating transcription factor binding(GO:0033613)
0.1 1.6 GO:0005112 Notch binding(GO:0005112)
0.0 0.5 GO:0061133 endopeptidase activator activity(GO:0061133)
0.0 2.1 GO:0030332 cyclin binding(GO:0030332)
0.0 2.8 GO:0003743 translation initiation factor activity(GO:0003743)
0.0 0.8 GO:0003708 retinoic acid receptor activity(GO:0003708)
0.0 1.0 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.2 GO:1903135 cupric ion binding(GO:1903135)
0.0 12.1 GO:0003924 GTPase activity(GO:0003924)
0.0 0.8 GO:0070402 NADPH binding(GO:0070402)
0.0 0.5 GO:0051011 microtubule minus-end binding(GO:0051011)
0.0 6.1 GO:0017124 SH3 domain binding(GO:0017124)
0.0 6.7 GO:0005244 voltage-gated ion channel activity(GO:0005244) voltage-gated channel activity(GO:0022832)
0.0 0.7 GO:0042056 chemoattractant activity(GO:0042056)
0.0 0.2 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
0.0 3.3 GO:0003735 structural constituent of ribosome(GO:0003735)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 13.8 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.7 42.3 PID THROMBIN PAR1 PATHWAY PAR1-mediated thrombin signaling events
0.6 21.7 PID S1P META PATHWAY Sphingosine 1-phosphate (S1P) pathway
0.4 17.0 PID AVB3 OPN PATHWAY Osteopontin-mediated events
0.4 2.8 ST IL 13 PATHWAY Interleukin 13 (IL-13) Pathway
0.4 35.4 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.4 10.7 ST GA12 PATHWAY G alpha 12 Pathway
0.4 10.0 PID NECTIN PATHWAY Nectin adhesion pathway
0.2 5.6 PID ARF 3PATHWAY Arf1 pathway
0.2 2.7 PID IL2 PI3K PATHWAY IL2 signaling events mediated by PI3K
0.2 4.9 PID LPA4 PATHWAY LPA4-mediated signaling events
0.2 23.1 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.2 9.1 PID CERAMIDE PATHWAY Ceramide signaling pathway
0.2 9.2 PID INTEGRIN3 PATHWAY Beta3 integrin cell surface interactions
0.2 3.4 PID FAS PATHWAY FAS (CD95) signaling pathway
0.2 5.5 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.2 6.6 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.1 1.4 PID LYSOPHOSPHOLIPID PATHWAY LPA receptor mediated events
0.1 4.6 PID ERBB2 ERBB3 PATHWAY ErbB2/ErbB3 signaling events
0.1 1.0 PID PI3K PLC TRK PATHWAY Trk receptor signaling mediated by PI3K and PLC-gamma
0.1 8.4 PID PI3KCI PATHWAY Class I PI3K signaling events
0.1 4.7 PID REELIN PATHWAY Reelin signaling pathway
0.1 2.3 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.1 2.9 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.1 2.5 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.1 0.7 ST STAT3 PATHWAY STAT3 Pathway
0.1 4.5 PID RAC1 PATHWAY RAC1 signaling pathway
0.1 8.5 PID HDAC CLASSI PATHWAY Signaling events mediated by HDAC Class I
0.1 5.1 PID VEGFR1 2 PATHWAY Signaling events mediated by VEGFR1 and VEGFR2
0.1 16.1 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.1 5.3 PID MTOR 4PATHWAY mTOR signaling pathway
0.1 7.0 PID AR PATHWAY Coregulation of Androgen receptor activity
0.1 3.1 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.1 2.3 PID CDC42 PATHWAY CDC42 signaling events
0.1 2.8 PID ILK PATHWAY Integrin-linked kinase signaling
0.1 1.9 PID ATM PATHWAY ATM pathway
0.1 2.0 PID FAK PATHWAY Signaling events mediated by focal adhesion kinase
0.0 2.6 PID P38 ALPHA BETA DOWNSTREAM PATHWAY Signaling mediated by p38-alpha and p38-beta
0.0 3.2 PID REG GR PATHWAY Glucocorticoid receptor regulatory network
0.0 1.7 PID ERBB1 INTERNALIZATION PATHWAY Internalization of ErbB1
0.0 1.9 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.0 0.8 PID RETINOIC ACID PATHWAY Retinoic acid receptors-mediated signaling
0.0 0.6 PID AP1 PATHWAY AP-1 transcription factor network
0.0 0.2 PID ARF6 PATHWAY Arf6 signaling events
0.0 0.2 PID GLYPICAN 1PATHWAY Glypican 1 network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 43.5 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.5 19.7 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
0.5 24.3 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.5 9.9 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.5 20.8 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.4 11.2 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.4 15.6 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.4 20.7 REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS Genes involved in Apoptotic cleavage of cellular proteins
0.4 3.9 REACTOME SEMA3A PAK DEPENDENT AXON REPULSION Genes involved in Sema3A PAK dependent Axon repulsion
0.3 4.9 REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY Genes involved in Adenylate cyclase activating pathway
0.3 3.2 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.3 13.4 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.2 12.4 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.2 2.1 REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC Genes involved in Regulation of ornithine decarboxylase (ODC)
0.2 3.1 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.2 8.4 REACTOME TRANSPORT OF RIBONUCLEOPROTEINS INTO THE HOST NUCLEUS Genes involved in Transport of Ribonucleoproteins into the Host Nucleus
0.2 10.9 REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS Genes involved in Thrombin signalling through proteinase activated receptors (PARs)
0.2 5.3 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.2 23.1 REACTOME POTASSIUM CHANNELS Genes involved in Potassium Channels
0.2 3.7 REACTOME GPVI MEDIATED ACTIVATION CASCADE Genes involved in GPVI-mediated activation cascade
0.2 4.9 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.2 3.5 REACTOME DESTABILIZATION OF MRNA BY TRISTETRAPROLIN TTP Genes involved in Destabilization of mRNA by Tristetraprolin (TTP)
0.2 16.0 REACTOME SIGNALING BY SCF KIT Genes involved in Signaling by SCF-KIT
0.2 3.2 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.2 5.3 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.1 1.5 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.1 2.6 REACTOME GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.1 20.3 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.1 5.8 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.1 2.4 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.1 2.1 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.1 1.3 REACTOME NFKB ACTIVATION THROUGH FADD RIP1 PATHWAY MEDIATED BY CASPASE 8 AND10 Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
0.1 1.3 REACTOME RNA POL I PROMOTER OPENING Genes involved in RNA Polymerase I Promoter Opening
0.1 1.9 REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.1 5.7 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.1 1.6 REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
0.1 1.8 REACTOME RNA POL III CHAIN ELONGATION Genes involved in RNA Polymerase III Chain Elongation
0.1 5.3 REACTOME MYOGENESIS Genes involved in Myogenesis
0.1 6.4 REACTOME L1CAM INTERACTIONS Genes involved in L1CAM interactions
0.1 15.8 REACTOME TRANSLATION Genes involved in Translation
0.1 3.1 REACTOME METAL ION SLC TRANSPORTERS Genes involved in Metal ion SLC transporters
0.1 11.5 REACTOME G ALPHA I SIGNALLING EVENTS Genes involved in G alpha (i) signalling events
0.1 6.4 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.1 0.5 REACTOME DOWNSTREAM SIGNAL TRANSDUCTION Genes involved in Downstream signal transduction
0.1 3.2 REACTOME CELL SURFACE INTERACTIONS AT THE VASCULAR WALL Genes involved in Cell surface interactions at the vascular wall
0.1 1.1 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.0 0.2 REACTOME ACTIVATION OF NF KAPPAB IN B CELLS Genes involved in Activation of NF-kappaB in B Cells
0.0 1.4 REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES Genes involved in Antiviral mechanism by IFN-stimulated genes
0.0 0.3 REACTOME ERKS ARE INACTIVATED Genes involved in ERKs are inactivated
0.0 9.0 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.0 0.3 REACTOME G ALPHA1213 SIGNALLING EVENTS Genes involved in G alpha (12/13) signalling events
0.0 2.2 REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.0 1.0 REACTOME TRAFFICKING OF AMPA RECEPTORS Genes involved in Trafficking of AMPA receptors
0.0 1.2 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 0.1 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.0 2.1 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0 2.1 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production