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GSE58827: Dynamics of the Mouse Liver

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Results for Fosl2_Bach2

Z-value: 0.78

Motif logo

Transcription factors associated with Fosl2_Bach2

Gene Symbol Gene ID Gene Info
ENSMUSG00000029135.11 fos-like antigen 2
ENSMUSG00000040270.17 BTB and CNC homology, basic leucine zipper transcription factor 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Fosl2mm39_v1_chr5_+_32293145_322932010.281.0e-01Click!
Bach2mm39_v1_chr4_+_32238712_322388040.163.5e-01Click!

Activity profile of Fosl2_Bach2 motif

Sorted Z-values of Fosl2_Bach2 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr11_-_102255999 19.49 ENSMUST00000006749.10
solute carrier family 4 (anion exchanger), member 1
chr1_-_132318039 15.43 ENSMUST00000132435.2
transmembrane and coiled-coil domains 2
chr8_+_95710977 10.23 ENSMUST00000093271.8
adhesion G protein-coupled receptor G1
chr7_+_78563964 9.90 ENSMUST00000120331.4
interferon-stimulated protein
chr7_-_126398343 9.73 ENSMUST00000032934.12
aldolase A, fructose-bisphosphate
chr7_+_78563513 9.63 ENSMUST00000038142.15
interferon-stimulated protein
chr3_-_88410495 9.08 ENSMUST00000120377.8
ENSMUST00000029699.13
lamin A
chr7_-_126398165 9.08 ENSMUST00000205890.2
ENSMUST00000205336.2
ENSMUST00000087566.11
aldolase A, fructose-bisphosphate
chr14_-_79539063 8.85 ENSMUST00000022595.8
regulator of cell cycle
chr2_+_164790139 8.42 ENSMUST00000017881.3
matrix metallopeptidase 9
chr1_+_174000304 8.13 ENSMUST00000027817.8
spectrin alpha, erythrocytic 1
chr7_+_78564062 7.84 ENSMUST00000205981.2
interferon-stimulated protein
chrX_-_7537580 6.86 ENSMUST00000033486.6
proteolipid protein 2
chr7_+_110371811 6.82 ENSMUST00000005829.13
adenosine monophosphate deaminase 3
chr13_+_95833359 6.56 ENSMUST00000022182.5
coagulation factor II (thrombin) receptor-like 2
chr3_+_93427791 6.36 ENSMUST00000029515.5
S100 calcium binding protein A11
chr8_+_95711037 5.77 ENSMUST00000211944.2
adhesion G protein-coupled receptor G1
chr9_+_69361348 5.48 ENSMUST00000134907.8
annexin A2
chr2_+_24226857 5.33 ENSMUST00000114487.9
ENSMUST00000142093.7
interleukin 1 receptor antagonist
chr9_+_69360902 5.03 ENSMUST00000034756.15
ENSMUST00000123470.8
annexin A2
chr1_+_75213258 4.87 ENSMUST00000185654.3
DnaJ heat shock protein family (Hsp40) member B2
chr7_+_110372860 4.71 ENSMUST00000143786.2
adenosine monophosphate deaminase 3
chr17_+_35268942 4.69 ENSMUST00000007257.10
chloride intracellular channel 1
chr11_-_78950641 4.05 ENSMUST00000226282.2
kinase suppressor of ras 1
chr8_+_94954280 3.84 ENSMUST00000109547.2
nucleoporin 93
chr7_+_126376353 3.69 ENSMUST00000106356.2
yippee like 3
chr7_+_110373447 3.57 ENSMUST00000147587.2
adenosine monophosphate deaminase 3
chr7_-_45570254 3.49 ENSMUST00000164119.3
epithelial membrane protein 3
chr7_-_45570538 3.47 ENSMUST00000210297.2
epithelial membrane protein 3
chr10_+_111309127 3.45 ENSMUST00000219143.2
nucleosome assembly protein 1-like 1
chr9_-_44253588 3.32 ENSMUST00000215091.2
hydroxymethylbilane synthase
chr6_-_115735935 3.29 ENSMUST00000072933.13
transmembrane protein 40
chr10_+_75404482 3.27 ENSMUST00000134503.8
ENSMUST00000125770.8
ENSMUST00000128886.8
ENSMUST00000151212.8
gamma-glutamyltransferase 1
chr2_+_84564394 3.21 ENSMUST00000238573.2
ENSMUST00000090729.9
yippee like 4
chr16_+_35590745 3.21 ENSMUST00000231579.2
Hspb associated protein 1
chr11_+_61575245 3.19 ENSMUST00000093019.6
family with sequence similarity 83, member G
chrX_-_133483849 3.17 ENSMUST00000113213.2
ENSMUST00000033617.13
Bruton agammaglobulinemia tyrosine kinase
chr2_-_25114660 3.14 ENSMUST00000043584.5
tubulin, beta 4B class IVB
chr11_-_109364424 3.11 ENSMUST00000070152.12
solute carrier family 16 (monocarboxylic acid transporters), member 6
chr7_-_19005721 3.09 ENSMUST00000032561.9
vasodilator-stimulated phosphoprotein
chr7_-_45570674 3.03 ENSMUST00000210939.2
epithelial membrane protein 3
chr3_-_129763638 2.84 ENSMUST00000146340.2
ENSMUST00000153506.8
mitochondrial calcium uniporter dominant negative beta subunit
chrX_-_165992311 2.81 ENSMUST00000112172.4
thymosin, beta 4, X chromosome
chr6_-_56878854 2.77 ENSMUST00000101367.9
5'-nucleotidase, cytosolic III
chr9_+_51124983 2.73 ENSMUST00000034554.9
POU domain, class 2, associating factor 1
chr3_+_95836558 2.68 ENSMUST00000165307.8
ENSMUST00000015893.13
ENSMUST00000169426.8
acidic (leucine-rich) nuclear phosphoprotein 32 family, member E
chrX_-_165992145 2.59 ENSMUST00000112176.8
thymosin, beta 4, X chromosome
chr1_+_75213171 2.59 ENSMUST00000187058.7
DnaJ heat shock protein family (Hsp40) member B2
chr2_-_113883285 2.49 ENSMUST00000090269.7
actin, alpha, cardiac muscle 1
chr7_+_126376099 2.47 ENSMUST00000038614.12
ENSMUST00000170882.8
ENSMUST00000106359.2
ENSMUST00000106357.8
ENSMUST00000145762.8
yippee like 3
chr3_+_95836637 2.45 ENSMUST00000171368.8
ENSMUST00000168106.8
acidic (leucine-rich) nuclear phosphoprotein 32 family, member E
chr4_-_140501507 2.43 ENSMUST00000026381.7
peptidyl arginine deiminase, type IV
chr4_+_132857816 2.41 ENSMUST00000084241.12
ENSMUST00000138831.2
WASP family, member 2
chr15_-_90563510 2.39 ENSMUST00000014777.9
ENSMUST00000064391.12
copine VIII
chr10_+_12966532 2.39 ENSMUST00000121646.8
ENSMUST00000121325.8
ENSMUST00000121766.8
pleiomorphic adenoma gene-like 1
chr6_+_42326760 2.38 ENSMUST00000203652.3
ENSMUST00000070635.13
zyxin
chr9_-_44253630 2.31 ENSMUST00000097558.5
hydroxymethylbilane synthase
chr4_-_6454262 2.30 ENSMUST00000029910.12
neutral sphingomyelinase (N-SMase) activation associated factor
chr11_+_116422712 2.28 ENSMUST00000100201.10
sphingosine kinase 1
chr11_+_116422570 2.26 ENSMUST00000106387.9
sphingosine kinase 1
chr6_+_86605146 2.25 ENSMUST00000043400.9
aspartic peptidase, retroviral-like 1
chr1_+_172328768 2.23 ENSMUST00000111228.2
transgelin 2
chr8_+_34222058 2.22 ENSMUST00000167264.8
ENSMUST00000187392.7
general transcription factor II E, polypeptide 2 (beta subunit)
chr1_+_75213082 2.19 ENSMUST00000055223.14
ENSMUST00000082158.13
ENSMUST00000188346.7
DnaJ heat shock protein family (Hsp40) member B2
chr8_+_34221861 2.13 ENSMUST00000170705.8
general transcription factor II E, polypeptide 2 (beta subunit)
chr12_+_103354915 2.11 ENSMUST00000101094.9
ENSMUST00000021620.13
OTU domain, ubiquitin aldehyde binding 2
chr2_+_13578738 2.10 ENSMUST00000141365.3
ENSMUST00000028062.8
vimentin
chr7_-_105131407 2.08 ENSMUST00000047040.4
caveolae associated 3
chr10_+_75404464 2.04 ENSMUST00000145928.8
ENSMUST00000131565.8
gamma-glutamyltransferase 1
chr15_-_38518406 2.02 ENSMUST00000151319.8
antizyme inhibitor 1
chr11_-_95733235 2.02 ENSMUST00000059026.10
ABI family member 3
chr17_+_46471950 2.01 ENSMUST00000024748.14
ENSMUST00000172170.8
GTP binding protein 2
chr8_+_34222266 1.98 ENSMUST00000190675.2
ENSMUST00000171010.8
general transcription factor II E, polypeptide 2 (beta subunit)
chr3_+_107803225 1.95 ENSMUST00000172247.8
ENSMUST00000167387.8
glutathione S-transferase, mu 5
chr5_+_35156389 1.95 ENSMUST00000114281.8
ENSMUST00000114280.8
regulator of G-protein signaling 12
chr6_+_42326934 1.95 ENSMUST00000203401.3
ENSMUST00000164375.4
zyxin
chrX_+_73468140 1.93 ENSMUST00000135165.8
ENSMUST00000114128.8
ENSMUST00000004330.10
ENSMUST00000114133.9
ENSMUST00000114129.9
ENSMUST00000132749.2
inhibitor of kappaB kinase gamma
chr6_+_42326714 1.92 ENSMUST00000203846.3
zyxin
chr1_+_75213114 1.89 ENSMUST00000188290.7
DnaJ heat shock protein family (Hsp40) member B2
chr17_+_36152383 1.89 ENSMUST00000082337.13
mediator of DNA damage checkpoint 1
chr4_-_152533265 1.86 ENSMUST00000159840.8
ENSMUST00000105648.10
potassium voltage-gated channel, shaker-related subfamily, beta member 2
chr19_-_53020531 1.83 ENSMUST00000236008.2
ENSMUST00000237294.2
X-prolyl aminopeptidase (aminopeptidase P) 1, soluble
chr9_+_96078340 1.81 ENSMUST00000034982.16
ENSMUST00000188008.7
ENSMUST00000188750.7
ENSMUST00000185644.7
transcription factor Dp 2
chr11_+_78079243 1.81 ENSMUST00000002128.14
ENSMUST00000150941.8
RAB34, member RAS oncogene family
chr17_-_7050145 1.80 ENSMUST00000064234.7
ezrin
chr17_-_48145466 1.78 ENSMUST00000066368.13
MyoD family inhibitor
chr10_+_128745214 1.78 ENSMUST00000220308.2
CD63 antigen
chr3_+_107803137 1.77 ENSMUST00000004134.11
glutathione S-transferase, mu 5
chr7_+_120516967 1.77 ENSMUST00000207481.2
ENSMUST00000106483.4
ENSMUST00000033173.15
polymerase (RNA) III (DNA directed) polypeptide E
chr4_-_126215462 1.73 ENSMUST00000102617.5
ADP-ribosylserine hydrolase
chrX_-_103714653 1.72 ENSMUST00000042070.6
zinc finger, DHHC domain containing 15
chr5_-_24597009 1.70 ENSMUST00000059401.7
autophagy related 9B
chr18_-_43610829 1.65 ENSMUST00000057110.11
eukaryotic translation initiation factor 3, subunit J2
chr15_-_64184485 1.63 ENSMUST00000177083.8
ENSMUST00000177371.8
ArfGAP with SH3 domain, ankyrin repeat and PH domain1
chr17_+_29170924 1.61 ENSMUST00000153462.8
potassium channel tetramerisation domain containing 20
chr3_+_92123106 1.59 ENSMUST00000074449.7
ENSMUST00000090871.3
small proline-rich protein 2A1
small proline-rich protein 2A2
chrX_-_47543029 1.57 ENSMUST00000114958.8
E74-like factor 4 (ets domain transcription factor)
chrX_+_71006577 1.57 ENSMUST00000048790.7
proline rich Gla (G-carboxyglutamic acid) 3 (transmembrane)
chr18_+_82928959 1.55 ENSMUST00000171238.8
zinc finger protein 516
chr11_-_78950698 1.54 ENSMUST00000141409.8
kinase suppressor of ras 1
chr7_+_4463686 1.51 ENSMUST00000167298.2
ENSMUST00000171445.8
EPS8-like 1
chr14_+_79753055 1.51 ENSMUST00000110835.3
ENSMUST00000227192.2
E74-like factor 1
chr7_+_27186335 1.48 ENSMUST00000008528.8
SERTA domain containing 1
chr4_-_6454097 1.46 ENSMUST00000124344.2
neutral sphingomyelinase (N-SMase) activation associated factor
chr17_+_29171655 1.42 ENSMUST00000117672.9
ENSMUST00000153831.9
potassium channel tetramerisation domain containing 20
chr10_+_87926932 1.41 ENSMUST00000048621.8
pro-melanin-concentrating hormone
chr8_-_61407760 1.39 ENSMUST00000110302.8
chloride channel, voltage-sensitive 3
chr6_-_143045493 1.32 ENSMUST00000204655.3
ENSMUST00000111758.9
C2 calcium-dependent domain containing 5
chr17_-_57501170 1.29 ENSMUST00000005976.8
tumor necrosis factor (ligand) superfamily, member 14
chr18_-_38131766 1.25 ENSMUST00000236588.2
ENSMUST00000237272.2
ENSMUST00000236134.2
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3
chr10_+_111309020 1.25 ENSMUST00000065917.16
ENSMUST00000219961.2
ENSMUST00000217908.2
nucleosome assembly protein 1-like 1
chr5_+_35156454 1.25 ENSMUST00000114283.8
regulator of G-protein signaling 12
chr5_-_21990170 1.24 ENSMUST00000115193.8
ENSMUST00000115192.2
ENSMUST00000115195.8
ENSMUST00000030771.12
DnaJ heat shock protein family (Hsp40) member C2
chr4_+_43506966 1.22 ENSMUST00000030183.10
carbonic anhydrase 9
chr10_+_127126643 1.21 ENSMUST00000026475.15
ENSMUST00000139091.2
ENSMUST00000230446.2
DNA-damage inducible transcript 3
DNA-damage inducible transcript 3
chr1_+_75213044 1.20 ENSMUST00000188931.7
DnaJ heat shock protein family (Hsp40) member B2
chr5_+_25452342 1.19 ENSMUST00000114950.2
polypeptide N-acetylgalactosaminyltransferase 11
chr7_-_16657825 1.18 ENSMUST00000019514.10
calmodulin 3
chr7_+_18817767 1.14 ENSMUST00000032568.14
ENSMUST00000122999.8
ENSMUST00000108473.10
ENSMUST00000108474.2
ENSMUST00000238982.2
dystrophia myotonica-protein kinase
chr6_-_116650751 1.13 ENSMUST00000204576.2
ENSMUST00000203029.3
ENSMUST00000035842.7
Ras association (RalGDS/AF-6) domain family member 4
chr14_-_56499690 1.11 ENSMUST00000015581.6
granzyme B
chr16_+_33614715 1.10 ENSMUST00000023520.7
mucin 13, epithelial transmembrane
chr10_-_128334515 1.10 ENSMUST00000026428.4
myosin, light polypeptide 6B
chr5_+_105563605 1.08 ENSMUST00000112707.3
leucine rich repeat containing 8 family, member B
chr2_+_30331839 1.08 ENSMUST00000131476.8
protein phosphatase 2 protein activator
chr15_+_84553801 1.06 ENSMUST00000171460.8
proline rich 5 (renal)
chr2_-_101627999 1.05 ENSMUST00000171088.8
ENSMUST00000043845.14
proline rich 5 like
chr6_+_42326980 1.05 ENSMUST00000203849.2
zyxin
chr19_+_4644425 1.05 ENSMUST00000238089.2
pyruvate carboxylase
chr11_+_78079631 1.05 ENSMUST00000056241.12
ENSMUST00000207728.2
RAB34, member RAS oncogene family
chr3_-_10273628 1.04 ENSMUST00000029041.6
fatty acid binding protein 4, adipocyte
chr6_+_135339543 1.04 ENSMUST00000205156.3
epithelial membrane protein 1
chr1_-_75195127 1.02 ENSMUST00000079464.13
tubulin, alpha 4A
chrX_-_7606445 1.00 ENSMUST00000128289.8
coiled-coil domain containing 120
chr6_+_42326528 0.99 ENSMUST00000203329.3
zyxin
chr11_-_100098333 0.97 ENSMUST00000007272.8
keratin 14
chrX_-_100266032 0.96 ENSMUST00000120389.8
ENSMUST00000156473.8
ENSMUST00000077876.4
sorting nexin 12
chr1_-_52271455 0.95 ENSMUST00000114512.8
glutaminase
chr19_-_46327024 0.95 ENSMUST00000236046.2
ENSMUST00000236980.2
ENSMUST00000235485.2
ENSMUST00000236061.2
ENSMUST00000236236.2
ENSMUST00000236768.2
ENSMUST00000236651.2
CUE domain containing 2
chr16_-_44379226 0.94 ENSMUST00000114634.3
biregional cell adhesion molecule-related/down-regulated by oncogenes (Cdon) binding protein
chr4_+_109263820 0.92 ENSMUST00000124209.8
tetratricopeptide repeat domain 39A
chrX_+_95498965 0.92 ENSMUST00000033553.14
hephaestin
chr18_-_70186503 0.92 ENSMUST00000117692.8
ENSMUST00000069749.9
RAB27B, member RAS oncogene family
chr6_+_56979285 0.92 ENSMUST00000079669.7
vomeronasal 1 receptor 6
chr19_-_46327071 0.90 ENSMUST00000235977.2
ENSMUST00000167861.8
ENSMUST00000051234.9
ENSMUST00000236066.2
CUE domain containing 2
chrX_-_156275231 0.89 ENSMUST00000112529.8
spermine synthase
chr19_-_34143437 0.88 ENSMUST00000025686.9
ankyrin repeat domain 22
chr8_-_108315024 0.88 ENSMUST00000044106.6
proteasome (prosome, macropain) 26S subunit, non-ATPase, 7
chr12_-_84240781 0.87 ENSMUST00000110294.2
mitotic deacetylase associated SANT domain protein
chr2_+_151414524 0.86 ENSMUST00000028950.9
syndecan binding protein (syntenin) 2
chr1_+_153625161 0.84 ENSMUST00000086209.10
ribonuclease L (2', 5'-oligoisoadenylate synthetase-dependent)
chr7_+_126184108 0.84 ENSMUST00000039522.8
apolipoprotein B receptor
chr11_-_69556888 0.83 ENSMUST00000108654.3
CD68 antigen
chr19_-_8690330 0.83 ENSMUST00000206598.2
solute carrier family 3 (activators of dibasic and neutral amino acid transport), member 2
chr1_+_153625243 0.82 ENSMUST00000182722.8
ribonuclease L (2', 5'-oligoisoadenylate synthetase-dependent)
chr11_-_69556904 0.81 ENSMUST00000018918.12
CD68 antigen
chr12_+_111725282 0.80 ENSMUST00000239017.2
ENSMUST00000084941.12
kinesin light chain 1
chr12_+_31315270 0.80 ENSMUST00000002979.16
ENSMUST00000239496.2
ENSMUST00000170495.3
laminin B1
chr10_-_76562002 0.79 ENSMUST00000001147.5
collagen, type VI, alpha 1
chr14_-_86986541 0.77 ENSMUST00000226254.2
diaphanous related formin 3
chr10_+_115979787 0.77 ENSMUST00000105271.9
protein tyrosine phosphatase, receptor type, R
chr8_-_25581354 0.76 ENSMUST00000125466.2
pleckstrin homology domain-containing, family A (phosphoinositide binding specific) member 2
chr16_+_20470402 0.76 ENSMUST00000007212.9
ENSMUST00000232629.2
proteasome (prosome, macropain) 26S subunit, non-ATPase, 2
chr8_+_121215155 0.76 ENSMUST00000034279.16
genetic suppressor element 1, coiled-coil protein
chr12_+_111725357 0.76 ENSMUST00000118471.8
ENSMUST00000122300.8
kinesin light chain 1
chr10_+_128247598 0.76 ENSMUST00000096386.13
ring finger protein 41
chrX_+_161684563 0.75 ENSMUST00000112303.8
ENSMUST00000033727.14
cytidine 5'-triphosphate synthase 2
chrX_+_158623460 0.74 ENSMUST00000112451.8
ENSMUST00000112453.9
SH3-domain kinase binding protein 1
chr9_-_78388080 0.74 ENSMUST00000156988.2
eukaryotic translation elongation factor 1 alpha 1
chrX_+_161684221 0.74 ENSMUST00000101095.9
cytidine 5'-triphosphate synthase 2
chr16_+_36755338 0.73 ENSMUST00000023531.15
hematopoietic cell specific Lyn substrate 1
chr7_-_44861541 0.73 ENSMUST00000033057.9
dickkopf-like 1
chr3_+_64884839 0.72 ENSMUST00000239069.2
potassium voltage-gated channel, shaker-related subfamily, beta member 1
chrX_-_10083157 0.70 ENSMUST00000072393.9
ENSMUST00000044598.13
ENSMUST00000073392.11
ENSMUST00000115533.8
ENSMUST00000115532.2
retinitis pigmentosa GTPase regulator
chr13_-_61084358 0.70 ENSMUST00000225859.2
ENSMUST00000225167.2
ENSMUST00000021880.10
predicted gene, 49391
cytotoxic T lymphocyte-associated protein 2 alpha
chr7_-_112946481 0.69 ENSMUST00000117577.8
BTB (POZ) domain containing 10
chr19_-_32188413 0.68 ENSMUST00000151289.9
sphingomyelin synthase 1
chr7_-_44861235 0.68 ENSMUST00000210741.2
ENSMUST00000209466.2
dickkopf-like 1
chr17_-_45903410 0.68 ENSMUST00000166119.8
solute carrier family 29 (nucleoside transporters), member 1
chr10_+_80765900 0.67 ENSMUST00000015456.10
ENSMUST00000220246.2
growth arrest and DNA-damage-inducible 45 beta
chr17_-_32569480 0.67 ENSMUST00000235265.2
ENSMUST00000236503.2
ENSMUST00000050214.9
A kinase (PRKA) anchor protein 8-like
chr2_+_156317416 0.64 ENSMUST00000029155.16
erythrocyte membrane protein band 4.1 like 1
chr7_-_141925947 0.64 ENSMUST00000084412.6
interferon induced transmembrane protein 10
chr10_+_128247492 0.64 ENSMUST00000171342.3
ring finger protein 41
chr6_-_129484070 0.63 ENSMUST00000183258.8
ENSMUST00000182784.4
ENSMUST00000032265.13
ENSMUST00000162815.2
oxidized low density lipoprotein (lectin-like) receptor 1
chr17_-_37178079 0.63 ENSMUST00000025329.13
ENSMUST00000174195.8
tripartite motif-containing 15
chr13_+_20295672 0.63 ENSMUST00000180626.2
engulfment and cell motility 1
chr11_+_75546671 0.61 ENSMUST00000108431.3
myosin IC
chr1_-_75193937 0.61 ENSMUST00000186971.2
ENSMUST00000188593.2
tubulin, alpha 4A
chr14_+_76714350 0.60 ENSMUST00000140251.9
TSC22 domain family, member 1
chr17_-_45883421 0.59 ENSMUST00000130406.2
heat shock protein 90 alpha (cytosolic), class B member 1
chr12_+_31315227 0.59 ENSMUST00000169088.8
laminin B1
chr13_-_91053440 0.59 ENSMUST00000109541.4
ATPase, H+ transporting, lysosomal accessory protein 1-like
chr11_+_80274105 0.58 ENSMUST00000165565.8
ENSMUST00000188489.7
ENSMUST00000017567.14
ENSMUST00000108216.8
ENSMUST00000053740.15
zinc finger protein 207
chr17_-_15261701 0.58 ENSMUST00000097398.12
ENSMUST00000040746.8
ENSMUST00000097400.5
dynein light chain Tctex-type 2A1
dynein light chain Tctex-type 2A2
chr4_+_128999325 0.58 ENSMUST00000106064.10
ENSMUST00000030575.15
ENSMUST00000030577.11
transmembrane protein 54
chr18_-_38471962 0.57 ENSMUST00000139885.2
ENSMUST00000235590.2
ENSMUST00000237487.2
ENSMUST00000063814.15
glucosamine-6-phosphate deaminase 1
chr12_+_111505216 0.57 ENSMUST00000050993.11
eukaryotic translation initiation factor 5
chr14_+_51181956 0.56 ENSMUST00000178092.2
ENSMUST00000227052.2
purine-nucleoside phosphorylase
predicted gene, 49342
chr15_-_38518458 0.56 ENSMUST00000127848.2
antizyme inhibitor 1

Network of associatons between targets according to the STRING database.

First level regulatory network of Fosl2_Bach2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
4.6 27.4 GO:0000738 DNA catabolic process, exonucleolytic(GO:0000738)
3.0 8.9 GO:0003331 regulation of extracellular matrix constituent secretion(GO:0003330) positive regulation of extracellular matrix constituent secretion(GO:0003331)
2.8 8.4 GO:0071460 cellular response to cell-matrix adhesion(GO:0071460)
1.9 5.6 GO:0018160 peptidyl-pyrromethane cofactor linkage(GO:0018160)
1.8 12.7 GO:1903644 regulation of chaperone-mediated protein folding(GO:1903644)
1.5 9.1 GO:0030951 establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951)
1.5 15.1 GO:0032264 IMP salvage(GO:0032264)
1.5 10.5 GO:0052205 modulation of molecular function in other organism(GO:0044359) negative regulation of molecular function in other organism(GO:0044362) negative regulation of molecular function in other organism involved in symbiotic interaction(GO:0052204) modulation of molecular function in other organism involved in symbiotic interaction(GO:0052205) negative regulation by host of symbiont molecular function(GO:0052405) modification by host of symbiont molecular function(GO:0052428)
1.2 5.9 GO:2000660 negative regulation of interleukin-1-mediated signaling pathway(GO:2000660)
1.1 19.2 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
1.1 3.2 GO:0002344 peripheral B cell selection(GO:0002343) B cell affinity maturation(GO:0002344)
0.7 2.1 GO:1901003 negative regulation of fermentation(GO:1901003)
0.7 5.3 GO:1901748 peptide modification(GO:0031179) leukotriene D4 metabolic process(GO:1901748) leukotriene D4 biosynthetic process(GO:1901750)
0.6 4.5 GO:0019371 cyclooxygenase pathway(GO:0019371)
0.6 2.6 GO:1902269 positive regulation of polyamine transmembrane transport(GO:1902269)
0.6 16.0 GO:0021796 cerebral cortex regionalization(GO:0021796)
0.6 3.2 GO:0038032 termination of G-protein coupled receptor signaling pathway(GO:0038032)
0.6 3.2 GO:1905161 protein localization to phagocytic vesicle(GO:1905161) regulation of protein localization to phagocytic vesicle(GO:1905169) positive regulation of protein localization to phagocytic vesicle(GO:1905171)
0.6 3.7 GO:0051410 detoxification of nitrogen compound(GO:0051410) cellular detoxification of nitrogen compound(GO:0070458)
0.6 15.9 GO:0015701 bicarbonate transport(GO:0015701)
0.5 3.8 GO:0090521 glomerular visceral epithelial cell migration(GO:0090521)
0.5 5.4 GO:0090343 positive regulation of cell aging(GO:0090343) positive regulation of cellular senescence(GO:2000774)
0.5 2.4 GO:0018101 protein citrullination(GO:0018101) histone citrullination(GO:0036414)
0.5 1.4 GO:0046005 positive regulation of circadian sleep/wake cycle, REM sleep(GO:0046005)
0.5 1.4 GO:0097401 synaptic vesicle lumen acidification(GO:0097401)
0.4 1.8 GO:1902896 terminal web assembly(GO:1902896)
0.4 1.3 GO:0008588 release of cytoplasmic sequestered NF-kappaB(GO:0008588)
0.4 2.0 GO:0070966 nuclear-transcribed mRNA catabolic process, no-go decay(GO:0070966)
0.4 11.6 GO:0032060 bleb assembly(GO:0032060)
0.4 1.2 GO:0046032 ADP catabolic process(GO:0046032)
0.4 1.1 GO:0030472 mitotic spindle organization in nucleus(GO:0030472)
0.4 1.1 GO:0036363 transforming growth factor beta activation(GO:0036363)
0.3 1.4 GO:0021812 neuronal-glial interaction involved in cerebral cortex radial glia guided migration(GO:0021812)
0.3 1.0 GO:2000642 negative regulation of early endosome to late endosome transport(GO:2000642)
0.3 5.4 GO:0051152 positive regulation of smooth muscle cell differentiation(GO:0051152)
0.3 1.6 GO:0035617 stress granule disassembly(GO:0035617)
0.3 1.2 GO:2000016 negative regulation of determination of dorsal identity(GO:2000016)
0.3 1.8 GO:2000680 regulation of rubidium ion transport(GO:2000680)
0.3 0.9 GO:0006597 spermine biosynthetic process(GO:0006597)
0.3 1.9 GO:0010936 negative regulation of macrophage cytokine production(GO:0010936)
0.3 2.1 GO:1900147 Schwann cell migration(GO:0036135) regulation of Schwann cell migration(GO:1900147)
0.3 2.8 GO:0036444 calcium ion transmembrane import into mitochondrion(GO:0036444)
0.2 2.5 GO:0030240 skeletal muscle thin filament assembly(GO:0030240)
0.2 2.1 GO:0038203 TORC2 signaling(GO:0038203)
0.2 1.6 GO:1903527 positive regulation of membrane tubulation(GO:1903527)
0.2 1.1 GO:0014722 regulation of skeletal muscle contraction by calcium ion signaling(GO:0014722)
0.2 1.1 GO:0008626 granzyme-mediated apoptotic signaling pathway(GO:0008626)
0.2 1.7 GO:0044805 late nucleophagy(GO:0044805)
0.2 1.0 GO:0019074 viral genome packaging(GO:0019072) viral RNA genome packaging(GO:0019074)
0.2 6.6 GO:0051482 positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway(GO:0051482)
0.2 8.1 GO:0006779 porphyrin-containing compound biosynthetic process(GO:0006779)
0.2 5.1 GO:0043486 histone exchange(GO:0043486)
0.2 0.6 GO:0046122 purine deoxyribonucleoside metabolic process(GO:0046122)
0.2 1.8 GO:0010815 bradykinin catabolic process(GO:0010815)
0.2 1.4 GO:1901525 negative regulation of macromitophagy(GO:1901525)
0.2 0.8 GO:0060356 leucine import(GO:0060356)
0.2 0.5 GO:0042275 error-free postreplication DNA repair(GO:0042275)
0.2 1.0 GO:0006543 glutamine catabolic process(GO:0006543)
0.2 0.5 GO:0051794 regulation of catagen(GO:0051794)
0.1 1.2 GO:0018243 protein O-linked glycosylation via threonine(GO:0018243)
0.1 1.5 GO:0035021 negative regulation of Rac protein signal transduction(GO:0035021)
0.1 1.7 GO:0016188 synaptic vesicle maturation(GO:0016188)
0.1 0.4 GO:1902938 regulation of intracellular calcium activated chloride channel activity(GO:1902938)
0.1 2.1 GO:0035871 protein K11-linked deubiquitination(GO:0035871)
0.1 2.8 GO:0046085 adenosine metabolic process(GO:0046085)
0.1 0.9 GO:0071985 multivesicular body sorting pathway(GO:0071985)
0.1 0.5 GO:0071544 diphosphoinositol polyphosphate catabolic process(GO:0071544)
0.1 0.8 GO:0038128 ERBB2 signaling pathway(GO:0038128)
0.1 0.9 GO:0015862 uridine transport(GO:0015862)
0.1 0.6 GO:1901252 regulation of intracellular transport of viral material(GO:1901252)
0.1 0.9 GO:0045110 intermediate filament bundle assembly(GO:0045110)
0.1 9.0 GO:0042982 amyloid precursor protein metabolic process(GO:0042982)
0.1 2.2 GO:0070995 NADPH oxidation(GO:0070995)
0.1 0.6 GO:0006002 fructose 6-phosphate metabolic process(GO:0006002) glucosamine metabolic process(GO:0006041)
0.1 0.4 GO:0010286 heat acclimation(GO:0010286) regulation of interleukin-1-mediated signaling pathway(GO:2000659)
0.1 0.4 GO:1903575 cornified envelope assembly(GO:1903575)
0.1 1.3 GO:0038028 insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028)
0.1 1.5 GO:0046036 CTP biosynthetic process(GO:0006241) CTP metabolic process(GO:0046036)
0.1 0.4 GO:2001280 positive regulation of prostaglandin biosynthetic process(GO:0031394) positive regulation of unsaturated fatty acid biosynthetic process(GO:2001280)
0.1 0.4 GO:1902340 telomeric heterochromatin assembly(GO:0031509) negative regulation of chromosome condensation(GO:1902340)
0.1 4.7 GO:1902476 chloride transmembrane transport(GO:1902476)
0.1 0.7 GO:0010793 regulation of mRNA export from nucleus(GO:0010793)
0.1 2.4 GO:0010592 positive regulation of lamellipodium assembly(GO:0010592)
0.1 1.6 GO:0007250 activation of NF-kappaB-inducing kinase activity(GO:0007250)
0.1 0.4 GO:0002266 follicular dendritic cell activation(GO:0002266) follicular dendritic cell differentiation(GO:0002268)
0.1 4.7 GO:0006334 nucleosome assembly(GO:0006334)
0.1 0.4 GO:0040031 snRNA modification(GO:0040031)
0.1 1.1 GO:0030277 maintenance of gastrointestinal epithelium(GO:0030277)
0.1 0.5 GO:1900748 positive regulation of vascular endothelial growth factor signaling pathway(GO:1900748)
0.1 0.9 GO:0030854 positive regulation of granulocyte differentiation(GO:0030854)
0.1 5.3 GO:0019933 cAMP-mediated signaling(GO:0019933)
0.1 0.2 GO:2000321 positive regulation of T-helper 17 cell differentiation(GO:2000321)
0.1 6.3 GO:0006367 transcription initiation from RNA polymerase II promoter(GO:0006367)
0.1 0.3 GO:0000454 snoRNA guided rRNA pseudouridine synthesis(GO:0000454) telomerase RNA stabilization(GO:0090669)
0.1 1.6 GO:0060707 trophoblast giant cell differentiation(GO:0060707)
0.1 1.0 GO:0071285 cellular response to lithium ion(GO:0071285)
0.1 0.5 GO:0021506 anterior neuropore closure(GO:0021506) neuropore closure(GO:0021995)
0.1 1.1 GO:0030049 muscle filament sliding(GO:0030049)
0.1 0.7 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.0 1.0 GO:2001275 positive regulation of glucose import in response to insulin stimulus(GO:2001275)
0.0 0.6 GO:0001866 NK T cell proliferation(GO:0001866)
0.0 0.5 GO:0007021 tubulin complex assembly(GO:0007021)
0.0 0.5 GO:0016479 negative regulation of transcription from RNA polymerase I promoter(GO:0016479)
0.0 0.5 GO:2001140 regulation of phospholipid transport(GO:2001138) positive regulation of phospholipid transport(GO:2001140)
0.0 0.2 GO:1900245 positive regulation of MDA-5 signaling pathway(GO:1900245)
0.0 0.9 GO:0034389 lipid particle organization(GO:0034389)
0.0 0.3 GO:0033007 negative regulation of mast cell activation involved in immune response(GO:0033007) negative regulation of mast cell degranulation(GO:0043305)
0.0 0.4 GO:0015074 DNA integration(GO:0015074)
0.0 0.3 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.0 0.9 GO:0006825 copper ion transport(GO:0006825)
0.0 0.1 GO:0016240 autophagosome docking(GO:0016240)
0.0 2.1 GO:0050873 brown fat cell differentiation(GO:0050873)
0.0 0.4 GO:1900004 regulation of serine-type endopeptidase activity(GO:1900003) negative regulation of serine-type endopeptidase activity(GO:1900004) regulation of serine-type peptidase activity(GO:1902571) negative regulation of serine-type peptidase activity(GO:1902572)
0.0 0.8 GO:0070208 protein heterotrimerization(GO:0070208)
0.0 1.7 GO:0032355 response to estradiol(GO:0032355)
0.0 0.1 GO:0002767 immune response-inhibiting cell surface receptor signaling pathway(GO:0002767)
0.0 0.4 GO:0031936 negative regulation of chromatin silencing(GO:0031936)
0.0 0.5 GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.0 0.3 GO:0010825 positive regulation of centrosome duplication(GO:0010825)
0.0 1.2 GO:2000279 negative regulation of DNA biosynthetic process(GO:2000279)
0.0 0.5 GO:1900037 regulation of cellular response to hypoxia(GO:1900037)
0.0 0.3 GO:0051490 negative regulation of filopodium assembly(GO:0051490)
0.0 0.7 GO:1902260 negative regulation of delayed rectifier potassium channel activity(GO:1902260)
0.0 0.4 GO:0001731 formation of translation preinitiation complex(GO:0001731)
0.0 7.9 GO:0007160 cell-matrix adhesion(GO:0007160)
0.0 0.5 GO:0070935 3'-UTR-mediated mRNA stabilization(GO:0070935)
0.0 0.2 GO:1903912 negative regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation(GO:1903912)
0.0 0.7 GO:0045589 regulation of regulatory T cell differentiation(GO:0045589)
0.0 0.1 GO:0007290 spermatid nucleus elongation(GO:0007290)
0.0 1.2 GO:0006730 one-carbon metabolic process(GO:0006730)
0.0 0.1 GO:0018214 protein carboxylation(GO:0018214)
0.0 0.7 GO:0071364 cellular response to epidermal growth factor stimulus(GO:0071364)
0.0 2.4 GO:0051289 protein homotetramerization(GO:0051289)
0.0 0.1 GO:1903028 regulation of opsonization(GO:1903027) positive regulation of opsonization(GO:1903028)
0.0 0.3 GO:2000671 regulation of motor neuron apoptotic process(GO:2000671)
0.0 0.1 GO:0021762 substantia nigra development(GO:0021762)
0.0 0.1 GO:2000821 regulation of grooming behavior(GO:2000821)
0.0 0.4 GO:0014883 transition between fast and slow fiber(GO:0014883)
0.0 0.2 GO:0061470 T follicular helper cell differentiation(GO:0061470)
0.0 0.1 GO:0051684 maintenance of Golgi location(GO:0051684)
0.0 0.1 GO:1904306 positive regulation of gastro-intestinal system smooth muscle contraction(GO:1904306)
0.0 0.4 GO:0045663 positive regulation of myoblast differentiation(GO:0045663)
0.0 0.1 GO:0061723 glycophagy(GO:0061723)
0.0 0.3 GO:0016973 poly(A)+ mRNA export from nucleus(GO:0016973)
0.0 0.1 GO:0032489 regulation of Cdc42 protein signal transduction(GO:0032489)
0.0 2.0 GO:0035914 skeletal muscle cell differentiation(GO:0035914)
0.0 0.9 GO:0045600 positive regulation of fat cell differentiation(GO:0045600)
0.0 0.2 GO:0097264 self proteolysis(GO:0097264)
0.0 2.6 GO:0030509 BMP signaling pathway(GO:0030509)
0.0 0.6 GO:0007094 mitotic spindle assembly checkpoint(GO:0007094) attachment of spindle microtubules to kinetochore(GO:0008608)
0.0 0.5 GO:0032011 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.0 0.7 GO:0042462 eye photoreceptor cell development(GO:0042462)
0.0 0.6 GO:0030890 positive regulation of B cell proliferation(GO:0030890)
0.0 0.1 GO:0000103 sulfate assimilation(GO:0000103)
0.0 0.5 GO:0030866 cortical actin cytoskeleton organization(GO:0030866)
0.0 0.1 GO:0060478 acrosomal vesicle exocytosis(GO:0060478)
0.0 1.4 GO:0000086 G2/M transition of mitotic cell cycle(GO:0000086)
0.0 0.1 GO:2001180 negative regulation of interleukin-10 secretion(GO:2001180)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
3.5 10.5 GO:1990667 PCSK9-AnxA2 complex(GO:1990667)
2.1 6.3 GO:0005673 transcription factor TFIIE complex(GO:0005673)
1.5 16.0 GO:0097451 glial limiting end-foot(GO:0097451)
1.4 8.1 GO:0032437 cuticular plate(GO:0032437)
1.3 9.1 GO:0005638 lamin filament(GO:0005638)
0.9 22.5 GO:0035686 sperm fibrous sheath(GO:0035686)
0.8 2.5 GO:0042643 actomyosin, actin portion(GO:0042643)
0.7 2.2 GO:1990031 pinceau fiber(GO:1990031)
0.6 1.8 GO:0098592 cytoplasmic side of apical plasma membrane(GO:0098592)
0.6 1.8 GO:0031904 endosome lumen(GO:0031904)
0.5 27.4 GO:0015030 Cajal body(GO:0015030)
0.4 1.3 GO:0005607 laminin-2 complex(GO:0005607)
0.4 2.8 GO:1990246 uniplex complex(GO:1990246)
0.4 1.2 GO:0036488 CHOP-C/EBP complex(GO:0036488) CHOP-ATF3 complex(GO:1990622)
0.3 3.1 GO:0045298 tubulin complex(GO:0045298)
0.2 1.1 GO:0044194 cytolytic granule(GO:0044194)
0.2 1.1 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
0.2 2.1 GO:0045098 type III intermediate filament(GO:0045098)
0.2 0.9 GO:0032585 multivesicular body membrane(GO:0032585)
0.1 16.2 GO:0014704 intercalated disc(GO:0014704)
0.1 2.1 GO:0031932 TORC2 complex(GO:0031932)
0.1 1.8 GO:0008385 IkappaB kinase complex(GO:0008385)
0.1 0.5 GO:0045160 myosin I complex(GO:0045160)
0.1 1.5 GO:0031209 SCAR complex(GO:0031209)
0.1 1.1 GO:0016461 unconventional myosin complex(GO:0016461)
0.1 10.2 GO:0000502 proteasome complex(GO:0000502)
0.1 0.5 GO:0033553 rDNA heterochromatin(GO:0033553)
0.1 1.5 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
0.1 1.8 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.1 0.4 GO:0033257 Bcl3/NF-kappaB2 complex(GO:0033257)
0.1 1.0 GO:0000138 Golgi trans cisterna(GO:0000138)
0.1 4.7 GO:0034707 chloride channel complex(GO:0034707)
0.1 1.6 GO:0035253 ciliary rootlet(GO:0035253)
0.1 1.4 GO:0042581 specific granule(GO:0042581)
0.0 0.2 GO:0000308 cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308)
0.0 1.6 GO:0002102 podosome(GO:0002102)
0.0 1.4 GO:0071782 endoplasmic reticulum tubular network(GO:0071782)
0.0 0.1 GO:0030868 smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425)
0.0 1.1 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.0 3.7 GO:0005643 nuclear pore(GO:0005643)
0.0 0.5 GO:0031371 ubiquitin conjugating enzyme complex(GO:0031371)
0.0 0.6 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.0 2.6 GO:0045335 phagocytic vesicle(GO:0045335)
0.0 0.4 GO:0000788 nuclear nucleosome(GO:0000788)
0.0 0.5 GO:0097512 cardiac myofibril(GO:0097512)
0.0 0.2 GO:0072559 NLRP3 inflammasome complex(GO:0072559)
0.0 0.5 GO:0005662 DNA replication factor A complex(GO:0005662)
0.0 1.1 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.7 GO:0042627 chylomicron(GO:0042627)
0.0 0.4 GO:0005861 troponin complex(GO:0005861)
0.0 0.7 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.0 4.4 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)
0.0 0.8 GO:0016592 mediator complex(GO:0016592)
0.0 0.7 GO:0001533 cornified envelope(GO:0001533)
0.0 0.3 GO:0031616 spindle pole centrosome(GO:0031616)
0.0 0.5 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.0 0.2 GO:0042599 lamellar body(GO:0042599)
0.0 5.1 GO:0000793 condensed chromosome(GO:0000793)
0.0 2.3 GO:0016363 nuclear matrix(GO:0016363)
0.0 2.3 GO:0001725 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0 0.9 GO:0044295 axonal growth cone(GO:0044295)
0.0 0.7 GO:0032391 photoreceptor connecting cilium(GO:0032391)
0.0 0.2 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.0 0.4 GO:0042588 zymogen granule(GO:0042588)
0.0 3.1 GO:0030027 lamellipodium(GO:0030027)
0.0 0.3 GO:0034399 nuclear periphery(GO:0034399)
0.0 0.3 GO:0005732 small nucleolar ribonucleoprotein complex(GO:0005732)
0.0 0.5 GO:0032154 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 0.1 GO:1990316 ATG1/ULK1 kinase complex(GO:1990316)
0.0 0.1 GO:0097447 dendritic tree(GO:0097447)
0.0 1.2 GO:0030139 endocytic vesicle(GO:0030139)
0.0 0.3 GO:0005922 connexon complex(GO:0005922)
0.0 7.5 GO:0005813 centrosome(GO:0005813)
0.0 1.2 GO:0008076 voltage-gated potassium channel complex(GO:0008076)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
5.5 27.4 GO:0008859 exoribonuclease II activity(GO:0008859)
1.9 18.8 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
1.9 5.6 GO:0004418 hydroxymethylbilane synthase activity(GO:0004418)
1.8 5.3 GO:0005152 interleukin-1 receptor antagonist activity(GO:0005152)
1.6 6.6 GO:0015057 thrombin receptor activity(GO:0015057)
1.5 15.1 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
1.2 10.5 GO:0019834 phospholipase A2 inhibitor activity(GO:0019834)
0.9 3.8 GO:0016230 sphingomyelin phosphodiesterase activator activity(GO:0016230)
0.8 18.5 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.6 2.6 GO:0042978 ornithine decarboxylase activator activity(GO:0042978)
0.5 2.0 GO:0003883 CTP synthase activity(GO:0003883)
0.5 12.7 GO:0070628 proteasome binding(GO:0070628)
0.5 2.4 GO:0004668 protein-arginine deiminase activity(GO:0004668)
0.5 4.1 GO:0008481 sphinganine kinase activity(GO:0008481) D-erythro-sphingosine kinase activity(GO:0017050)
0.4 5.3 GO:0036374 glutathione hydrolase activity(GO:0036374)
0.3 1.4 GO:0005128 erythropoietin receptor binding(GO:0005128)
0.3 1.4 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
0.3 5.6 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.3 2.1 GO:0019784 NEDD8-specific protease activity(GO:0019784)
0.3 1.2 GO:0031800 type 3 metabotropic glutamate receptor binding(GO:0031800)
0.3 1.1 GO:0008160 protein tyrosine phosphatase activator activity(GO:0008160)
0.3 1.0 GO:0004736 pyruvate carboxylase activity(GO:0004736)
0.2 1.2 GO:0061649 ubiquitinated histone binding(GO:0061649)
0.2 6.6 GO:0019956 chemokine binding(GO:0019956)
0.2 9.1 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.2 8.8 GO:0070412 R-SMAD binding(GO:0070412)
0.2 7.9 GO:0001968 fibronectin binding(GO:0001968)
0.2 0.6 GO:0004342 glucosamine-6-phosphate deaminase activity(GO:0004342)
0.2 0.6 GO:0004731 purine-nucleoside phosphorylase activity(GO:0004731)
0.2 1.4 GO:0043208 glycosphingolipid binding(GO:0043208)
0.2 15.1 GO:0005518 collagen binding(GO:0005518)
0.2 1.0 GO:0004359 glutaminase activity(GO:0004359)
0.2 1.7 GO:0032558 adenyl deoxyribonucleotide binding(GO:0032558)
0.1 1.2 GO:0047631 ADP-ribose diphosphatase activity(GO:0047631)
0.1 3.7 GO:0017160 Ral GTPase binding(GO:0017160)
0.1 5.1 GO:0019212 phosphatase inhibitor activity(GO:0019212)
0.1 2.2 GO:0005522 profilin binding(GO:0005522)
0.1 3.7 GO:1900750 glutathione binding(GO:0043295) oligopeptide binding(GO:1900750)
0.1 3.8 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.1 1.2 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.1 0.4 GO:0004909 interleukin-1, Type I, activating receptor activity(GO:0004909)
0.1 5.4 GO:0003785 actin monomer binding(GO:0003785)
0.1 2.9 GO:0004033 aldo-keto reductase (NADP) activity(GO:0004033)
0.1 0.5 GO:0051373 FATZ binding(GO:0051373)
0.1 0.7 GO:0030229 very-low-density lipoprotein particle receptor activity(GO:0030229)
0.1 0.5 GO:1990050 phosphatidic acid transporter activity(GO:1990050)
0.1 0.4 GO:1903135 cupric ion binding(GO:1903135)
0.1 1.8 GO:0001056 RNA polymerase III activity(GO:0001056)
0.1 0.9 GO:0016724 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.1 2.0 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.1 0.2 GO:0004947 bradykinin receptor activity(GO:0004947)
0.1 1.8 GO:0034236 protein kinase A catalytic subunit binding(GO:0034236)
0.1 0.3 GO:0003998 acylphosphatase activity(GO:0003998)
0.1 5.8 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.1 0.6 GO:0071074 eukaryotic initiation factor eIF2 binding(GO:0071074)
0.1 1.8 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.1 1.2 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.1 2.2 GO:0004190 aspartic-type endopeptidase activity(GO:0004190)
0.1 0.3 GO:0030280 structural constituent of epidermis(GO:0030280)
0.1 1.9 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.1 1.5 GO:0042608 T cell receptor binding(GO:0042608)
0.1 0.4 GO:0042030 ATPase inhibitor activity(GO:0042030)
0.1 0.6 GO:0005041 low-density lipoprotein receptor activity(GO:0005041)
0.1 0.3 GO:0008545 JUN kinase kinase activity(GO:0008545)
0.1 1.7 GO:0019706 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.1 3.2 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.1 7.9 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 1.3 GO:0031489 myosin V binding(GO:0031489)
0.0 0.4 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.0 2.7 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.0 0.5 GO:1990380 Lys48-specific deubiquitinase activity(GO:1990380)
0.0 1.1 GO:0008307 structural constituent of muscle(GO:0008307)
0.0 1.2 GO:0005112 Notch binding(GO:0005112)
0.0 1.5 GO:0017022 myosin binding(GO:0017022)
0.0 0.6 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.0 0.3 GO:0005225 volume-sensitive anion channel activity(GO:0005225)
0.0 0.5 GO:0001164 RNA polymerase I regulatory region sequence-specific DNA binding(GO:0001163) RNA polymerase I CORE element sequence-specific DNA binding(GO:0001164)
0.0 1.7 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 0.2 GO:0048039 ubiquinone binding(GO:0048039)
0.0 0.9 GO:0005337 nucleoside transmembrane transporter activity(GO:0005337)
0.0 2.0 GO:0003743 translation initiation factor activity(GO:0003743)
0.0 2.9 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.0 0.7 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 0.2 GO:0004439 phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity(GO:0004439) phosphatidylinositol phosphate 5-phosphatase activity(GO:0034595)
0.0 0.3 GO:0019855 calcium channel inhibitor activity(GO:0019855)
0.0 0.7 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.0 0.4 GO:0050308 sugar-phosphatase activity(GO:0050308)
0.0 0.3 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.0 0.2 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.0 1.7 GO:0019843 rRNA binding(GO:0019843)
0.0 3.7 GO:0017124 SH3 domain binding(GO:0017124)
0.0 1.0 GO:0005504 fatty acid binding(GO:0005504)
0.0 0.2 GO:0035497 cAMP response element binding(GO:0035497)
0.0 0.3 GO:0070034 telomerase RNA binding(GO:0070034)
0.0 3.8 GO:0022832 voltage-gated ion channel activity(GO:0005244) voltage-gated channel activity(GO:0022832)
0.0 0.5 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 0.5 GO:0017091 AU-rich element binding(GO:0017091)
0.0 1.4 GO:0003777 microtubule motor activity(GO:0003777)
0.0 0.6 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 0.4 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.0 0.1 GO:0004027 alcohol sulfotransferase activity(GO:0004027)
0.0 0.9 GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups(GO:0016765)
0.0 1.2 GO:0033613 activating transcription factor binding(GO:0033613)
0.0 0.3 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.0 0.8 GO:0001104 RNA polymerase II transcription cofactor activity(GO:0001104)
0.0 0.9 GO:0005550 pheromone binding(GO:0005550)
0.0 0.3 GO:0071855 neuropeptide receptor binding(GO:0071855)
0.0 0.2 GO:0070577 lysine-acetylated histone binding(GO:0070577)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 6.9 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.3 4.1 PID S1P S1P1 PATHWAY S1P1 pathway
0.2 9.0 PID AVB3 OPN PATHWAY Osteopontin-mediated events
0.2 11.4 PID THROMBIN PAR1 PATHWAY PAR1-mediated thrombin signaling events
0.2 8.7 PID CERAMIDE PATHWAY Ceramide signaling pathway
0.2 7.0 PID FAS PATHWAY FAS (CD95) signaling pathway
0.2 17.1 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.1 12.3 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.1 0.6 PID PI3K PLC TRK PATHWAY Trk receptor signaling mediated by PI3K and PLC-gamma
0.1 3.1 PID IL1 PATHWAY IL1-mediated signaling events
0.1 12.0 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.1 1.0 PID IL2 PI3K PATHWAY IL2 signaling events mediated by PI3K
0.0 0.6 ST STAT3 PATHWAY STAT3 Pathway
0.0 0.3 ST IL 13 PATHWAY Interleukin 13 (IL-13) Pathway
0.0 1.4 PID ERBB2 ERBB3 PATHWAY ErbB2/ErbB3 signaling events
0.0 1.8 PID PI3KCI PATHWAY Class I PI3K signaling events
0.0 0.9 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 1.3 PID ATM PATHWAY ATM pathway
0.0 1.5 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.0 0.7 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.0 0.5 PID LYSOPHOSPHOLIPID PATHWAY LPA receptor mediated events
0.0 1.9 PID FAK PATHWAY Signaling events mediated by focal adhesion kinase
0.0 1.2 PID FCER1 PATHWAY Fc-epsilon receptor I signaling in mast cells
0.0 0.7 PID ERBB1 INTERNALIZATION PATHWAY Internalization of ErbB1
0.0 1.2 PID RAC1 PATHWAY RAC1 signaling pathway
0.0 0.4 ST TUMOR NECROSIS FACTOR PATHWAY Tumor Necrosis Factor Pathway.
0.0 1.3 PID E2F PATHWAY E2F transcription factor network
0.0 0.8 PID CDC42 PATHWAY CDC42 signaling events
0.0 1.1 PID MTOR 4PATHWAY mTOR signaling pathway
0.0 0.8 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0 1.0 PID REG GR PATHWAY Glucocorticoid receptor regulatory network
0.0 0.7 PID P38 ALPHA BETA DOWNSTREAM PATHWAY Signaling mediated by p38-alpha and p38-beta
0.0 0.7 PID AP1 PATHWAY AP-1 transcription factor network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 15.7 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.4 29.1 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.4 18.5 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.2 4.8 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.2 5.6 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.2 9.0 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.2 9.1 REACTOME MEIOTIC SYNAPSIS Genes involved in Meiotic Synapsis
0.1 7.2 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.1 2.7 REACTOME PYRIMIDINE CATABOLISM Genes involved in Pyrimidine catabolism
0.1 1.8 REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1 Genes involved in IKK complex recruitment mediated by RIP1
0.1 6.3 REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.1 1.2 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.1 1.8 REACTOME RNA POL III CHAIN ELONGATION Genes involved in RNA Polymerase III Chain Elongation
0.1 3.1 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.1 3.8 REACTOME TRANSPORT OF RIBONUCLEOPROTEINS INTO THE HOST NUCLEUS Genes involved in Transport of Ribonucleoproteins into the Host Nucleus
0.1 3.0 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.1 15.7 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.1 5.1 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.1 4.9 REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS Genes involved in Thrombin signalling through proteinase activated receptors (PARs)
0.1 1.4 REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.1 1.3 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.1 0.6 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.1 0.4 REACTOME ADP SIGNALLING THROUGH P2RY1 Genes involved in ADP signalling through P2Y purinoceptor 1
0.1 2.1 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.1 1.1 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.0 2.9 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.0 0.9 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.0 1.6 REACTOME KINESINS Genes involved in Kinesins
0.0 2.6 REACTOME IL1 SIGNALING Genes involved in Interleukin-1 signaling
0.0 0.8 REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
0.0 2.0 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 1.8 REACTOME RECYCLING PATHWAY OF L1 Genes involved in Recycling pathway of L1
0.0 0.3 REACTOME G ALPHA1213 SIGNALLING EVENTS Genes involved in G alpha (12/13) signalling events
0.0 1.0 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 0.3 REACTOME JNK C JUN KINASES PHOSPHORYLATION AND ACTIVATION MEDIATED BY ACTIVATED HUMAN TAK1 Genes involved in JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1
0.0 0.4 REACTOME RNA POL I PROMOTER OPENING Genes involved in RNA Polymerase I Promoter Opening
0.0 1.1 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0 1.2 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.0 0.4 REACTOME TAK1 ACTIVATES NFKB BY PHOSPHORYLATION AND ACTIVATION OF IKKS COMPLEX Genes involved in TAK1 activates NFkB by phosphorylation and activation of IKKs complex
0.0 0.8 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0 0.4 REACTOME GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.0 1.1 REACTOME INTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Intrinsic Pathway for Apoptosis
0.0 1.2 REACTOME L1CAM INTERACTIONS Genes involved in L1CAM interactions
0.0 1.1 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 0.6 REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
0.0 1.2 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.0 0.5 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.6 REACTOME GPVI MEDIATED ACTIVATION CASCADE Genes involved in GPVI-mediated activation cascade
0.0 0.9 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.0 0.9 REACTOME IRON UPTAKE AND TRANSPORT Genes involved in Iron uptake and transport
0.0 0.3 REACTOME DESTABILIZATION OF MRNA BY TRISTETRAPROLIN TTP Genes involved in Destabilization of mRNA by Tristetraprolin (TTP)
0.0 0.4 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1
0.0 0.6 REACTOME TRAFFICKING OF AMPA RECEPTORS Genes involved in Trafficking of AMPA receptors
0.0 2.9 REACTOME G ALPHA I SIGNALLING EVENTS Genes involved in G alpha (i) signalling events
0.0 0.7 REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC Genes involved in Regulation of ornithine decarboxylase (ODC)
0.0 0.2 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation