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GSE58827: Dynamics of the Mouse Liver

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Results for Foxb1

Z-value: 0.55

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Transcription factors associated with Foxb1

Gene Symbol Gene ID Gene Info
Foxb1
ENSMUSG00000059246.5 forkhead box B1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Foxb1mm39_v1_chr9_-_69668204_69668222-0.154.0e-01Click!

Activity profile of Foxb1 motif

Sorted Z-values of Foxb1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr19_+_20579322 5.58 ENSMUST00000087638.4
Aldh1a1
aldehyde dehydrogenase family 1, subfamily A1
chr10_+_127734384 5.14 ENSMUST00000047134.8
Sdr9c7
4short chain dehydrogenase/reductase family 9C, member 7
chr19_-_20704896 4.15 ENSMUST00000025656.4
Aldh1a7
aldehyde dehydrogenase family 1, subfamily A7
chr7_+_119499322 1.55 ENSMUST00000106516.2
Lyrm1
LYR motif containing 1
chr19_-_40175709 1.36 ENSMUST00000051846.13
Cyp2c70
cytochrome P450, family 2, subfamily c, polypeptide 70
chr3_-_95811993 1.35 ENSMUST00000147962.3
ENSMUST00000036181.15
Car14
carbonic anhydrase 14
chr3_-_146302343 1.33 ENSMUST00000029836.9
Dnase2b
deoxyribonuclease II beta
chr12_-_84497718 1.30 ENSMUST00000085192.7
ENSMUST00000220491.2
Aldh6a1
aldehyde dehydrogenase family 6, subfamily A1
chr11_-_86884507 0.86 ENSMUST00000018571.5
Ypel2
yippee like 2
chr7_+_27290969 0.79 ENSMUST00000108344.9
Akt2
thymoma viral proto-oncogene 2
chr14_+_48358267 0.78 ENSMUST00000073150.6
Peli2
pellino 2
chr3_+_96152813 0.74 ENSMUST00000078756.7
ENSMUST00000090779.4
H2ac18
Gm20634
H2A clustered histone 18
predicted gene 20634
chr7_+_18962252 0.68 ENSMUST00000063976.9
Opa3
optic atrophy 3
chr7_+_67305162 0.68 ENSMUST00000107470.2
Ttc23
tetratricopeptide repeat domain 23
chr3_-_96147592 0.67 ENSMUST00000074976.8
H2ac19
H2A clustered histone 19
chr7_+_27291126 0.64 ENSMUST00000167435.8
Akt2
thymoma viral proto-oncogene 2
chr5_+_102629365 0.62 ENSMUST00000112854.8
Arhgap24
Rho GTPase activating protein 24
chr1_-_170695328 0.62 ENSMUST00000027974.7
Atf6
activating transcription factor 6
chr14_+_48358331 0.61 ENSMUST00000226513.2
Peli2
pellino 2
chr4_-_135221810 0.60 ENSMUST00000105856.9
Nipal3
NIPA-like domain containing 3
chr14_-_55880708 0.58 ENSMUST00000120041.8
ENSMUST00000121937.8
ENSMUST00000133707.2
ENSMUST00000002391.15
ENSMUST00000121791.8
Tm9sf1
transmembrane 9 superfamily member 1
chr9_+_47441471 0.57 ENSMUST00000114548.8
ENSMUST00000152459.8
ENSMUST00000143026.9
ENSMUST00000085909.9
ENSMUST00000114547.8
ENSMUST00000239368.2
ENSMUST00000214542.2
ENSMUST00000034581.4
Cadm1
cell adhesion molecule 1
chr7_+_18962301 0.57 ENSMUST00000161711.2
Opa3
optic atrophy 3
chr12_-_32000534 0.56 ENSMUST00000172314.9
Hbp1
high mobility group box transcription factor 1
chr5_+_3707171 0.54 ENSMUST00000198739.5
Tmbim7
transmembrane BAX inhibitor motif containing 7
chr6_+_14901343 0.53 ENSMUST00000115477.8
Foxp2
forkhead box P2
chr6_+_14901439 0.51 ENSMUST00000128567.8
Foxp2
forkhead box P2
chr10_+_69761630 0.51 ENSMUST00000182029.8
Ank3
ankyrin 3, epithelial
chr16_-_44153288 0.51 ENSMUST00000136381.8
Sidt1
SID1 transmembrane family, member 1
chr3_+_59939175 0.50 ENSMUST00000029325.5
Aadac
arylacetamide deacetylase
chr3_+_63148887 0.49 ENSMUST00000194324.6
Mme
membrane metallo endopeptidase
chr17_+_35188888 0.48 ENSMUST00000173680.2
Gm20481
predicted gene 20481
chr2_-_147028309 0.47 ENSMUST00000067075.7
Nkx2-2
NK2 homeobox 2
chr10_+_111342147 0.47 ENSMUST00000164773.2
Phlda1
pleckstrin homology like domain, family A, member 1
chr5_+_102629240 0.47 ENSMUST00000073302.12
ENSMUST00000094559.9
Arhgap24
Rho GTPase activating protein 24
chr11_+_78356523 0.47 ENSMUST00000001126.4
Slc46a1
solute carrier family 46, member 1
chr4_-_135221926 0.47 ENSMUST00000102549.10
Nipal3
NIPA-like domain containing 3
chr18_+_38809771 0.46 ENSMUST00000134388.2
ENSMUST00000148850.8
9630014M24Rik
Arhgap26
RIKEN cDNA 9630014M24 gene
Rho GTPase activating protein 26
chr2_-_45001141 0.43 ENSMUST00000201969.4
ENSMUST00000201623.4
Zeb2
zinc finger E-box binding homeobox 2
chr12_-_32000209 0.42 ENSMUST00000176084.2
ENSMUST00000176103.8
ENSMUST00000167458.9
Hbp1
high mobility group box transcription factor 1
chr12_+_112645237 0.41 ENSMUST00000174780.2
ENSMUST00000169593.2
ENSMUST00000173942.2
Zbtb42
zinc finger and BTB domain containing 42
chr6_+_15184630 0.40 ENSMUST00000115470.3
Foxp2
forkhead box P2
chr3_+_85946145 0.40 ENSMUST00000238331.2
Sh3d19
SH3 domain protein D19
chr3_-_92922976 0.40 ENSMUST00000107301.2
ENSMUST00000029521.5
Crct1
cysteine-rich C-terminal 1
chr6_+_8948608 0.40 ENSMUST00000160300.2
Nxph1
neurexophilin 1
chr8_+_94763826 0.39 ENSMUST00000109556.9
ENSMUST00000093301.9
ENSMUST00000060632.8
Ogfod1
2-oxoglutarate and iron-dependent oxygenase domain containing 1
chr16_-_44153498 0.39 ENSMUST00000047446.13
Sidt1
SID1 transmembrane family, member 1
chrX_+_100419965 0.39 ENSMUST00000119080.8
Gjb1
gap junction protein, beta 1
chr3_-_123483772 0.37 ENSMUST00000172537.3
Ndst3
N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 3
chr6_+_15185202 0.36 ENSMUST00000154448.2
Foxp2
forkhead box P2
chr6_-_41535322 0.33 ENSMUST00000193003.2
Trbv31
T cell receptor beta, variable 31
chr1_-_39844467 0.33 ENSMUST00000171319.4
Gm3646
predicted gene 3646
chr5_+_104318542 0.32 ENSMUST00000112771.2
Dspp
dentin sialophosphoprotein
chr12_+_56742413 0.31 ENSMUST00000001538.10
Pax9
paired box 9
chr12_-_32000169 0.31 ENSMUST00000176520.8
Hbp1
high mobility group box transcription factor 1
chr12_-_40249489 0.31 ENSMUST00000220951.2
Lsmem1
leucine-rich single-pass membrane protein 1
chr4_+_11579648 0.31 ENSMUST00000180239.2
Fsbp
fibrinogen silencer binding protein
chr12_-_111946560 0.31 ENSMUST00000190680.2
Rd3l
retinal degeneration 3-like
chr6_-_41535292 0.30 ENSMUST00000103300.3
Trbv31
T cell receptor beta, variable 31
chr11_-_98220466 0.30 ENSMUST00000041685.7
Neurod2
neurogenic differentiation 2
chr15_+_102927366 0.29 ENSMUST00000165375.3
Hoxc4
homeobox C4
chr3_-_129597679 0.29 ENSMUST00000185462.7
ENSMUST00000179187.2
Lrit3
leucine-rich repeat, immunoglobulin-like and transmembrane domains 3
chr7_-_144761806 0.29 ENSMUST00000208788.2
Smim38
small integral membrane protein 38
chr6_+_34840151 0.29 ENSMUST00000202010.2
Tmem140
transmembrane protein 140
chr16_-_48232770 0.28 ENSMUST00000212197.2
Gm5485
predicted gene 5485
chr4_-_139560831 0.28 ENSMUST00000030508.14
Pax7
paired box 7
chr2_+_154042291 0.28 ENSMUST00000028987.7
Bpifb1
BPI fold containing family B, member 1
chr5_-_51725059 0.28 ENSMUST00000127135.3
Ppargc1a
peroxisome proliferative activated receptor, gamma, coactivator 1 alpha
chr18_+_37085673 0.27 ENSMUST00000192512.6
ENSMUST00000192295.2
ENSMUST00000115661.5
Pcdha4
Gm42416
protocadherin alpha 4
predicted gene, 42416
chr5_+_43673093 0.26 ENSMUST00000144558.3
C1qtnf7
C1q and tumor necrosis factor related protein 7
chr17_+_70829050 0.25 ENSMUST00000133717.9
ENSMUST00000148486.8
Dlgap1
DLG associated protein 1
chr10_+_69761597 0.24 ENSMUST00000182269.8
ENSMUST00000183261.8
ENSMUST00000183074.8
Ank3
ankyrin 3, epithelial
chr4_+_102287244 0.24 ENSMUST00000172616.2
Pde4b
phosphodiesterase 4B, cAMP specific
chr19_-_9065309 0.24 ENSMUST00000025554.3
Scgb1a1
secretoglobin, family 1A, member 1 (uteroglobin)
chr10_+_69761314 0.24 ENSMUST00000182692.8
ENSMUST00000092433.12
Ank3
ankyrin 3, epithelial
chr2_+_181409075 0.23 ENSMUST00000108757.9
Myt1
myelin transcription factor 1
chr17_+_70829144 0.23 ENSMUST00000140728.8
Dlgap1
DLG associated protein 1
chr17_-_35265702 0.22 ENSMUST00000097338.11
Msh5
mutS homolog 5
chr12_-_40249314 0.22 ENSMUST00000095760.3
Lsmem1
leucine-rich single-pass membrane protein 1
chr11_+_74252895 0.21 ENSMUST00000216362.2
Olfr412
olfactory receptor 412
chr7_-_141009264 0.21 ENSMUST00000164387.2
ENSMUST00000137488.2
ENSMUST00000084436.10
Cend1
cell cycle exit and neuronal differentiation 1
chr17_+_48037758 0.21 ENSMUST00000024782.12
ENSMUST00000144955.2
Pgc
progastricsin (pepsinogen C)
chrX_+_118836893 0.21 ENSMUST00000040961.3
ENSMUST00000113366.2
Pabpc5
poly(A) binding protein, cytoplasmic 5
chr5_-_3707166 0.21 ENSMUST00000196304.2
Gatad1
GATA zinc finger domain containing 1
chr4_+_127066667 0.20 ENSMUST00000106094.9
Dlgap3
DLG associated protein 3
chrX_+_56257374 0.20 ENSMUST00000033466.2
Cd40lg
CD40 ligand
chr3_-_33136153 0.20 ENSMUST00000108225.10
Pex5l
peroxisomal biogenesis factor 5-like
chr14_-_52252318 0.20 ENSMUST00000228051.2
Zfp219
zinc finger protein 219
chr7_-_141009346 0.20 ENSMUST00000124444.2
Cend1
cell cycle exit and neuronal differentiation 1
chr18_-_25886750 0.19 ENSMUST00000224553.2
ENSMUST00000025117.14
Celf4
CUGBP, Elav-like family member 4
chr4_-_102883905 0.19 ENSMUST00000084382.6
ENSMUST00000106869.3
Insl5
insulin-like 5
chrX_+_108138965 0.19 ENSMUST00000033598.9
Sh3bgrl
SH3-binding domain glutamic acid-rich protein like
chr17_+_93506590 0.19 ENSMUST00000064775.8
Adcyap1
adenylate cyclase activating polypeptide 1
chr15_+_102012782 0.18 ENSMUST00000230474.2
Tns2
tensin 2
chr3_+_133942244 0.18 ENSMUST00000181904.3
Cxxc4
CXXC finger 4
chr4_-_82970384 0.18 ENSMUST00000170248.9
Frem1
Fras1 related extracellular matrix protein 1
chr14_+_33193765 0.16 ENSMUST00000208577.2
Frmpd2
FERM and PDZ domain containing 2
chr8_-_65489791 0.16 ENSMUST00000124790.8
Apela
apelin receptor early endogenous ligand
chr17_+_93506435 0.15 ENSMUST00000234646.2
ENSMUST00000234081.2
Adcyap1
adenylate cyclase activating polypeptide 1
chr2_+_181408833 0.15 ENSMUST00000108756.8
Myt1
myelin transcription factor 1
chr7_-_119078330 0.15 ENSMUST00000207460.2
Umod
uromodulin
chr2_-_160701523 0.15 ENSMUST00000103112.8
Zhx3
zinc fingers and homeoboxes 3
chr4_+_109092829 0.14 ENSMUST00000030285.8
Calr4
calreticulin 4
chr1_+_179788037 0.14 ENSMUST00000097453.9
ENSMUST00000111117.8
Cdc42bpa
CDC42 binding protein kinase alpha
chr12_+_119291343 0.14 ENSMUST00000221917.2
Macc1
metastasis associated in colon cancer 1
chr17_+_12597490 0.13 ENSMUST00000014578.7
Plg
plasminogen
chr2_+_109522781 0.12 ENSMUST00000111050.10
Bdnf
brain derived neurotrophic factor
chr12_+_113038376 0.11 ENSMUST00000109729.3
Tex22
testis expressed gene 22
chr10_+_69761784 0.11 ENSMUST00000181974.8
ENSMUST00000182795.8
ENSMUST00000182437.8
Ank3
ankyrin 3, epithelial
chr10_-_49659355 0.10 ENSMUST00000105484.10
ENSMUST00000218598.2
ENSMUST00000079751.9
ENSMUST00000218441.2
Grik2
glutamate receptor, ionotropic, kainate 2 (beta 2)
chr18_+_69652751 0.10 ENSMUST00000200966.4
Tcf4
transcription factor 4
chr1_+_187995096 0.10 ENSMUST00000060479.14
Ush2a
usherin
chr5_+_143803540 0.10 ENSMUST00000100487.6
Eif2ak1
eukaryotic translation initiation factor 2 alpha kinase 1
chr2_-_60552980 0.09 ENSMUST00000028348.9
ENSMUST00000112517.8
Itgb6
integrin beta 6
chr6_+_34840057 0.09 ENSMUST00000074949.4
Tmem140
transmembrane protein 140
chr14_-_52252432 0.09 ENSMUST00000226527.2
Zfp219
zinc finger protein 219
chr2_+_153742294 0.07 ENSMUST00000088955.12
ENSMUST00000135501.3
Bpifb6
BPI fold containing family B, member 6
chr1_+_179788675 0.07 ENSMUST00000076687.12
ENSMUST00000097450.10
ENSMUST00000212756.2
Cdc42bpa
CDC42 binding protein kinase alpha
chr7_+_103593644 0.06 ENSMUST00000216006.2
Olfr633
olfactory receptor 633
chr6_-_134768288 0.06 ENSMUST00000149776.3
Dusp16
dual specificity phosphatase 16
chr3_-_102690026 0.06 ENSMUST00000172026.8
ENSMUST00000170856.6
Tshb
thyroid stimulating hormone, beta subunit
chr10_-_33662700 0.06 ENSMUST00000223295.2
Sult3a2
sulfotransferase family 3A, member 2
chr19_-_11852453 0.06 ENSMUST00000213954.2
ENSMUST00000217617.2
Olfr1419
olfactory receptor 1419
chr1_-_158642039 0.06 ENSMUST00000161589.3
Pappa2
pappalysin 2
chr8_-_62576140 0.06 ENSMUST00000034052.14
ENSMUST00000034054.9
Anxa10
annexin A10
chr1_+_70764874 0.05 ENSMUST00000053922.12
ENSMUST00000161937.2
ENSMUST00000162182.2
Vwc2l
von Willebrand factor C domain-containing protein 2-like
chr15_-_48655329 0.05 ENSMUST00000160658.8
ENSMUST00000100670.10
ENSMUST00000162830.8
Csmd3
CUB and Sushi multiple domains 3
chr3_-_154760978 0.05 ENSMUST00000064076.6
Tnni3k
TNNI3 interacting kinase
chr7_-_103492361 0.04 ENSMUST00000063957.6
Hbb-bh1
hemoglobin Z, beta-like embryonic chain
chrX_-_42363663 0.03 ENSMUST00000016294.8
Tenm1
teneurin transmembrane protein 1
chr6_-_3494587 0.03 ENSMUST00000049985.15
Hepacam2
HEPACAM family member 2
chr5_-_87630117 0.03 ENSMUST00000079811.13
ENSMUST00000144144.3
Ugt2a2
UDP glucuronosyltransferase 2 family, polypeptide A2
chr8_-_65489834 0.03 ENSMUST00000142822.4
Apela
apelin receptor early endogenous ligand
chrX_-_93166693 0.03 ENSMUST00000113925.8
Zfx
zinc finger protein X-linked
chr18_-_43820759 0.02 ENSMUST00000082254.8
Jakmip2
janus kinase and microtubule interacting protein 2
chr15_+_43340609 0.02 ENSMUST00000022962.8
Emc2
ER membrane protein complex subunit 2
chr9_-_101076198 0.02 ENSMUST00000066773.9
Ppp2r3a
protein phosphatase 2, regulatory subunit B'', alpha
chr4_+_109092610 0.02 ENSMUST00000106628.8
Calr4
calreticulin 4
chr6_-_139478919 0.01 ENSMUST00000170650.3
Rergl
RERG/RAS-like
chr3_+_88762971 0.01 ENSMUST00000212694.2
Gon4l
gon-4-like (C.elegans)

Network of associatons between targets according to the STRING database.

First level regulatory network of Foxb1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 5.6 GO:0042904 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.3 1.3 GO:0019859 pyrimidine nucleobase catabolic process(GO:0006208) thymine catabolic process(GO:0006210) thymine metabolic process(GO:0019859)
0.2 4.2 GO:0042573 retinoic acid metabolic process(GO:0042573)
0.2 1.4 GO:0071486 cellular response to light intensity(GO:0071484) cellular response to high light intensity(GO:0071486) retinal rod cell apoptotic process(GO:0097473)
0.2 0.5 GO:0021529 spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530)
0.1 1.4 GO:0008063 Toll signaling pathway(GO:0008063)
0.1 1.3 GO:0015670 carbon dioxide transport(GO:0015670)
0.1 0.6 GO:0042271 susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
0.1 1.8 GO:0060501 positive regulation of epithelial cell proliferation involved in lung morphogenesis(GO:0060501)
0.1 1.1 GO:0035021 negative regulation of Rac protein signal transduction(GO:0035021)
0.1 0.3 GO:0071460 cellular response to cell-matrix adhesion(GO:0071460)
0.1 0.4 GO:0021941 radial glia guided migration of cerebellar granule cell(GO:0021933) negative regulation of cerebellar granule cell precursor proliferation(GO:0021941)
0.1 0.3 GO:1904633 glomerular visceral epithelial cell apoptotic process(GO:1903210) regulation of glomerular visceral epithelial cell apoptotic process(GO:1904633) positive regulation of glomerular visceral epithelial cell apoptotic process(GO:1904635) positive regulation of progesterone biosynthetic process(GO:2000184)
0.1 1.1 GO:0010650 positive regulation of cell communication by electrical coupling(GO:0010650) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.1 0.9 GO:0033227 dsRNA transport(GO:0033227)
0.1 0.3 GO:2000297 negative regulation of synapse maturation(GO:2000297)
0.1 0.5 GO:0071492 cellular response to UV-A(GO:0071492)
0.1 0.2 GO:0002225 positive regulation of antimicrobial peptide production(GO:0002225) positive regulation of antibacterial peptide production(GO:0002803)
0.1 0.3 GO:0071651 positive regulation of chemokine (C-C motif) ligand 5 production(GO:0071651)
0.1 0.2 GO:2001200 positive regulation of dendritic cell differentiation(GO:2001200)
0.1 0.5 GO:0051958 heme transport(GO:0015886) methotrexate transport(GO:0051958)
0.1 1.3 GO:0010745 negative regulation of macrophage derived foam cell differentiation(GO:0010745)
0.1 0.2 GO:0032696 negative regulation of interleukin-13 production(GO:0032696)
0.1 1.3 GO:0006309 apoptotic DNA fragmentation(GO:0006309)
0.1 1.1 GO:0015693 magnesium ion transport(GO:0015693)
0.0 0.3 GO:1902748 positive regulation of lens fiber cell differentiation(GO:1902748)
0.0 0.4 GO:0006449 regulation of translational termination(GO:0006449)
0.0 0.4 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.0 0.1 GO:0061193 taste bud development(GO:0061193)
0.0 1.4 GO:0019373 epoxygenase P450 pathway(GO:0019373)
0.0 0.6 GO:1990440 positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress(GO:1990440)
0.0 0.5 GO:0070842 aggresome assembly(GO:0070842)
0.0 0.3 GO:0009786 regulation of asymmetric cell division(GO:0009786)
0.0 0.5 GO:0010898 positive regulation of triglyceride catabolic process(GO:0010898)
0.0 1.2 GO:0070584 mitochondrion morphogenesis(GO:0070584)
0.0 0.4 GO:0015868 purine ribonucleotide transport(GO:0015868)
0.0 0.3 GO:0014816 skeletal muscle satellite cell differentiation(GO:0014816)
0.0 0.3 GO:0034144 negative regulation of toll-like receptor 4 signaling pathway(GO:0034144)
0.0 0.2 GO:0016560 protein import into peroxisome matrix, docking(GO:0016560)
0.0 0.1 GO:0046501 protoporphyrinogen IX metabolic process(GO:0046501)
0.0 0.2 GO:1901898 negative regulation of relaxation of cardiac muscle(GO:1901898)
0.0 0.1 GO:0051918 negative regulation of fibrinolysis(GO:0051918)
0.0 0.1 GO:0038044 transforming growth factor-beta secretion(GO:0038044)
0.0 0.2 GO:1902866 regulation of retina development in camera-type eye(GO:1902866)
0.0 0.4 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.0 0.4 GO:0060539 diaphragm development(GO:0060539)
0.0 0.2 GO:0051026 chiasma assembly(GO:0051026)
0.0 0.1 GO:0048496 maintenance of organ identity(GO:0048496)
0.0 0.2 GO:2000253 positive regulation of feeding behavior(GO:2000253)
0.0 0.0 GO:0072218 ascending thin limb development(GO:0072021) thick ascending limb development(GO:0072023) metanephric ascending thin limb development(GO:0072218) metanephric thick ascending limb development(GO:0072233)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:1990844 subsarcolemmal mitochondrion(GO:1990843) interfibrillar mitochondrion(GO:1990844)
0.1 1.4 GO:0032593 insulin-responsive compartment(GO:0032593)
0.0 1.1 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.0 0.6 GO:0070852 cell body fiber(GO:0070852)
0.0 0.2 GO:0017071 intracellular cyclic nucleotide activated cation channel complex(GO:0017071)
0.0 0.1 GO:0060171 stereocilium membrane(GO:0060171)
0.0 0.1 GO:0044218 other organism cell membrane(GO:0044218) other organism membrane(GO:0044279)
0.0 0.1 GO:0034685 integrin alphav-beta6 complex(GO:0034685)
0.0 0.4 GO:0005922 connexon complex(GO:0005922)
0.0 0.1 GO:0032983 kainate selective glutamate receptor complex(GO:0032983)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.9 9.7 GO:0018479 benzaldehyde dehydrogenase (NAD+) activity(GO:0018479)
0.3 1.3 GO:0004531 deoxyribonuclease II activity(GO:0004531)
0.2 5.1 GO:0004745 retinol dehydrogenase activity(GO:0004745)
0.1 0.9 GO:0051033 nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033)
0.1 0.4 GO:0031544 peptidyl-proline 3-dioxygenase activity(GO:0031544)
0.1 0.5 GO:0015232 heme transporter activity(GO:0015232)
0.1 1.3 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.1 0.2 GO:0005174 CD40 receptor binding(GO:0005174)
0.1 1.1 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.1 0.4 GO:0042328 heparan sulfate N-acetylglucosaminyltransferase activity(GO:0042328)
0.0 0.1 GO:0005169 neurotrophin TRKB receptor binding(GO:0005169)
0.0 1.4 GO:0070330 aromatase activity(GO:0070330)
0.0 0.2 GO:0005052 peroxisome matrix targeting signal-1 binding(GO:0005052)
0.0 0.6 GO:0035497 cAMP response element binding(GO:0035497)
0.0 0.2 GO:0019834 phospholipase A2 inhibitor activity(GO:0019834)
0.0 0.5 GO:0004806 triglyceride lipase activity(GO:0004806)
0.0 0.4 GO:0005243 gap junction channel activity(GO:0005243)
0.0 0.1 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
0.0 1.3 GO:0016620 oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor(GO:0016620)
0.0 0.2 GO:0030983 mismatched DNA binding(GO:0030983)
0.0 0.1 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.0 1.1 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.0 1.1 GO:0030507 spectrin binding(GO:0030507)
0.0 0.3 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.0 2.8 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.0 0.3 GO:0005184 neuropeptide hormone activity(GO:0005184)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.4 SA TRKA RECEPTOR The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.0 1.3 PID MYC PATHWAY C-MYC pathway
0.0 0.9 PID P38 ALPHA BETA DOWNSTREAM PATHWAY Signaling mediated by p38-alpha and p38-beta

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 5.6 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.1 1.4 REACTOME IRAK1 RECRUITS IKK COMPLEX Genes involved in IRAK1 recruits IKK complex
0.1 1.4 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.1 0.6 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.1 1.3 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.0 1.1 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 0.5 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.0 0.4 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.0 0.6 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.1 REACTOME HORMONE LIGAND BINDING RECEPTORS Genes involved in Hormone ligand-binding receptors