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GSE58827: Dynamics of the Mouse Liver

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Results for Foxd1

Z-value: 1.44

Motif logo

Transcription factors associated with Foxd1

Gene Symbol Gene ID Gene Info
ENSMUSG00000078302.6 forkhead box D1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Foxd1mm39_v1_chr13_+_98490742_984907580.153.8e-01Click!

Activity profile of Foxd1 motif

Sorted Z-values of Foxd1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr11_-_102255999 18.52 ENSMUST00000006749.10
solute carrier family 4 (anion exchanger), member 1
chr5_-_138169509 18.09 ENSMUST00000153867.8
minichromosome maintenance complex component 7
chr5_-_138169253 17.46 ENSMUST00000139983.8
minichromosome maintenance complex component 7
chr17_+_47816042 15.26 ENSMUST00000183044.8
ENSMUST00000037333.17
cyclin D3
chr17_+_47815968 14.81 ENSMUST00000182129.8
ENSMUST00000171031.8
cyclin D3
chr17_+_47816074 14.73 ENSMUST00000183177.8
ENSMUST00000182848.8
cyclin D3
chr17_+_47816137 13.94 ENSMUST00000182935.8
ENSMUST00000182506.8
cyclin D3
chr11_+_74510413 13.38 ENSMUST00000100866.3
coiled-coil domain containing 92B
chr5_-_138169476 10.84 ENSMUST00000147920.2
minichromosome maintenance complex component 7
chr10_+_115653152 10.42 ENSMUST00000080630.11
ENSMUST00000179196.3
ENSMUST00000035563.15
tetraspanin 8
chr7_+_110371811 10.11 ENSMUST00000005829.13
adenosine monophosphate deaminase 3
chr14_-_71003973 8.12 ENSMUST00000226448.2
ENSMUST00000022696.8
exportin 7
chr9_+_96078340 7.65 ENSMUST00000034982.16
ENSMUST00000188008.7
ENSMUST00000188750.7
ENSMUST00000185644.7
transcription factor Dp 2
chr17_+_29712008 7.58 ENSMUST00000234665.2
proviral integration site 1
chr8_-_86107593 6.76 ENSMUST00000122452.8
myosin light chain kinase 3
chr14_-_71004019 6.76 ENSMUST00000167242.8
exportin 7
chr19_+_45433899 6.74 ENSMUST00000224478.2
beta-transducin repeat containing protein
chr8_+_70826191 6.61 ENSMUST00000003659.9
cartilage oligomeric matrix protein
chr15_+_80507671 6.45 ENSMUST00000043149.9
GRB2-related adaptor protein 2
chr6_-_83513222 6.33 ENSMUST00000075161.12
actin, gamma 2, smooth muscle, enteric
chr15_+_97682210 6.14 ENSMUST00000117892.2
ENSMUST00000229084.2
solute carrier family 48 (heme transporter), member 1
chr1_-_45542442 5.91 ENSMUST00000086430.5
collagen, type V, alpha 2
chrX_+_162923474 5.71 ENSMUST00000073973.11
angiotensin I converting enzyme (peptidyl-dipeptidase A) 2
chr9_+_96078299 5.70 ENSMUST00000165120.9
transcription factor Dp 2
chr15_+_79231720 5.62 ENSMUST00000096350.11
v-maf musculoaponeurotic fibrosarcoma oncogene family, protein F (avian)
chr15_+_79232137 5.51 ENSMUST00000163691.3
v-maf musculoaponeurotic fibrosarcoma oncogene family, protein F (avian)
chr13_+_55593116 5.46 ENSMUST00000001115.16
ENSMUST00000224995.2
ENSMUST00000225925.2
ENSMUST00000099482.5
ENSMUST00000224118.2
G protein-coupled receptor kinase 6
chr3_-_27208010 5.36 ENSMUST00000108300.8
ENSMUST00000108298.9
ect2 oncogene
chr5_-_148988110 5.29 ENSMUST00000110505.8
high mobility group box 1
chr19_-_41836514 5.09 ENSMUST00000059231.4
frequently rearranged in advanced T cell lymphomas 2
chr2_-_152239966 4.82 ENSMUST00000063332.9
ENSMUST00000182625.2
SRY (sex determining region Y)-box 12
chr1_+_134343152 4.78 ENSMUST00000112237.2
adiponectin receptor 1
chr2_-_163486998 4.78 ENSMUST00000017851.4
serine incorporator 3
chr3_-_27207993 4.71 ENSMUST00000176242.9
ENSMUST00000176780.8
ect2 oncogene
chr6_+_135339543 4.67 ENSMUST00000205156.3
epithelial membrane protein 1
chr19_+_53317844 4.59 ENSMUST00000111737.3
ENSMUST00000025998.15
ENSMUST00000237837.2
MAX interactor 1, dimerization protein
chr6_+_30541581 4.56 ENSMUST00000096066.5
carboxypeptidase A2, pancreatic
chr15_-_51855073 4.56 ENSMUST00000022927.11
RAD21 cohesin complex component
chr1_+_134343107 4.53 ENSMUST00000027727.15
adiponectin receptor 1
chr6_-_83513184 4.35 ENSMUST00000205926.2
actin, gamma 2, smooth muscle, enteric
chr11_+_33996920 4.26 ENSMUST00000052413.12
lymphocyte cytosolic protein 2
chr11_+_101623836 4.24 ENSMUST00000129741.2
DEAH (Asp-Glu-Ala-His) box polypeptide 8
chr4_+_11191726 4.17 ENSMUST00000029866.16
ENSMUST00000108324.4
cyclin E2
chr11_+_33997114 4.16 ENSMUST00000109329.9
lymphocyte cytosolic protein 2
chr5_+_31409021 4.01 ENSMUST00000054829.13
ENSMUST00000201625.4
ENSMUST00000201937.4
keratinocyte associated protein 3
chr7_+_126376099 3.99 ENSMUST00000038614.12
ENSMUST00000170882.8
ENSMUST00000106359.2
ENSMUST00000106357.8
ENSMUST00000145762.8
yippee like 3
chr15_+_61857226 3.83 ENSMUST00000161976.8
ENSMUST00000022971.8
myelocytomatosis oncogene
chr11_+_101623776 3.77 ENSMUST00000039152.14
DEAH (Asp-Glu-Ala-His) box polypeptide 8
chr7_-_25488060 3.65 ENSMUST00000002677.11
ENSMUST00000085948.11
AXL receptor tyrosine kinase
chr14_+_26722319 3.62 ENSMUST00000035433.10
homeobox gene expressed in ES cells
chr7_+_126376353 3.40 ENSMUST00000106356.2
yippee like 3
chr5_-_148988413 3.33 ENSMUST00000093196.11
high mobility group box 1
chr15_+_61857390 3.32 ENSMUST00000159327.2
ENSMUST00000167731.8
myelocytomatosis oncogene
chr13_-_98951890 3.17 ENSMUST00000040340.16
ENSMUST00000179563.8
ENSMUST00000109403.2
FCH domain only 2
chr11_+_68986043 3.11 ENSMUST00000101004.9
period circadian clock 1
chr4_-_128699838 3.04 ENSMUST00000106072.9
ENSMUST00000170934.3
zinc finger protein 362
chr11_+_96820220 3.02 ENSMUST00000062172.6
proline rich 15-like
chr15_-_97729341 3.01 ENSMUST00000079838.14
ENSMUST00000118294.8
histone deacetylase 7
chr11_+_96820091 2.96 ENSMUST00000054311.6
ENSMUST00000107636.4
proline rich 15-like
chr7_-_141614758 2.95 ENSMUST00000211000.2
ENSMUST00000209725.2
ENSMUST00000084418.4
MOB kinase activator 2
chr3_-_129834788 2.90 ENSMUST00000168644.3
Sec24 related gene family, member B (S. cerevisiae)
chr6_+_142244145 2.84 ENSMUST00000041993.3
islet amyloid polypeptide
chr19_-_7319157 2.77 ENSMUST00000164205.8
ENSMUST00000165286.8
ENSMUST00000168324.2
ENSMUST00000032557.15
MAP/microtubule affinity regulating kinase 2
chr7_-_115423934 2.77 ENSMUST00000169129.8
SRY (sex determining region Y)-box 6
chrX_+_100298134 2.75 ENSMUST00000062000.6
forkhead box O4
chr3_+_102965910 2.72 ENSMUST00000199367.5
ENSMUST00000199049.5
ENSMUST00000197678.5
neuroblastoma ras oncogene
chr4_+_132857816 2.70 ENSMUST00000084241.12
ENSMUST00000138831.2
WASP family, member 2
chr3_+_96465265 2.70 ENSMUST00000074519.13
ENSMUST00000049093.8
thioredoxin interacting protein
chr7_-_83304698 2.70 ENSMUST00000145610.8
interleukin 16
chr11_+_3280401 2.68 ENSMUST00000045153.11
phosphoinositide-3-kinase interacting protein 1
chr1_+_12788720 2.66 ENSMUST00000088585.10
sulfatase 1
chr15_+_79232591 2.65 ENSMUST00000229285.2
v-maf musculoaponeurotic fibrosarcoma oncogene family, protein F (avian)
chr19_+_7534838 2.62 ENSMUST00000141887.8
ENSMUST00000136756.2
phospholipase A and acyltransferase 3
chr4_-_149760488 2.57 ENSMUST00000118704.8
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta
chr6_+_135339929 2.55 ENSMUST00000032330.16
epithelial membrane protein 1
chr7_-_29204812 2.52 ENSMUST00000183096.8
ENSMUST00000085809.11
signal-induced proliferation-associated 1 like 3
chr19_+_58748132 2.51 ENSMUST00000026081.5
pancreatic lipase-related protein 2
chr13_-_96803216 2.49 ENSMUST00000170287.8
3-hydroxy-3-methylglutaryl-Coenzyme A reductase
chr2_+_127967951 2.46 ENSMUST00000089634.12
ENSMUST00000019281.14
ENSMUST00000110341.9
ENSMUST00000103211.8
ENSMUST00000103210.2
BCL2-like 11 (apoptosis facilitator)
chr18_+_36797113 2.43 ENSMUST00000036765.8
eukaryotic translation initiation factor 4E binding protein 3
chr3_-_143910926 2.42 ENSMUST00000120539.8
ENSMUST00000196264.5
LIM domain only 4
chr2_-_84652890 2.41 ENSMUST00000028471.6
smoothelin-like 1
chr12_+_69343450 2.40 ENSMUST00000021362.5
kelch domain containing 2
chr19_+_7534816 2.39 ENSMUST00000136465.8
ENSMUST00000025925.11
phospholipase A and acyltransferase 3
chr18_-_47466378 2.38 ENSMUST00000126684.2
ENSMUST00000156422.8
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A
chr10_-_80513927 2.36 ENSMUST00000199949.2
MAP kinase-interacting serine/threonine kinase 2
chr13_+_104315301 2.27 ENSMUST00000022225.12
ENSMUST00000069187.12
tripartite motif-containing 23
chr9_-_108526548 2.27 ENSMUST00000013338.14
ENSMUST00000193197.6
ariadne RBR E3 ubiquitin protein ligase 2
chr5_-_123127346 2.25 ENSMUST00000118027.8
lysine (K)-specific demethylase 2B
chr8_+_106785434 2.21 ENSMUST00000212742.2
ENSMUST00000211991.2
nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 3
chr7_-_141614590 2.19 ENSMUST00000211206.2
MOB kinase activator 2
chr4_-_117146624 2.15 ENSMUST00000221654.2
ring finger protein 220
chr3_-_102871440 2.09 ENSMUST00000058899.13
nuclear receptor subfamily 1, group H, member 5
chr17_+_35413415 2.09 ENSMUST00000025262.6
ENSMUST00000173600.2
lymphotoxin B
chr15_-_79430742 2.03 ENSMUST00000231053.2
ENSMUST00000229431.2
DEAD box helicase 17
chr5_-_137530214 2.03 ENSMUST00000140139.2
guanine nucleotide binding protein (G protein), beta 2
chr17_-_27816151 2.01 ENSMUST00000231742.2
nudix (nucleotide diphosphate linked moiety X)-type motif 3
chrX_+_41238193 2.00 ENSMUST00000115073.9
ENSMUST00000115072.8
stromal antigen 2
chr3_+_129326004 2.00 ENSMUST00000199910.5
ENSMUST00000197070.5
ENSMUST00000071402.7
ELOVL family member 6, elongation of long chain fatty acids (yeast)
chr2_+_14878480 1.99 ENSMUST00000114719.7
calcium channel, voltage-dependent, beta 2 subunit
chr11_+_3280771 1.99 ENSMUST00000136536.8
ENSMUST00000093399.11
phosphoinositide-3-kinase interacting protein 1
chr1_+_179373935 1.94 ENSMUST00000040706.9
consortin, connexin sorting protein
chr4_+_11191354 1.92 ENSMUST00000170901.8
cyclin E2
chr3_-_52012462 1.88 ENSMUST00000121440.4
mastermind like transcriptional coactivator 3
chr15_+_35296237 1.84 ENSMUST00000022952.6
odd-skipped related 2
chr4_+_94627513 1.81 ENSMUST00000073939.13
ENSMUST00000102798.8
TEK receptor tyrosine kinase
chr2_-_59955995 1.80 ENSMUST00000112550.8
bromodomain adjacent to zinc finger domain, 2B
chr5_-_123127148 1.80 ENSMUST00000046073.16
lysine (K)-specific demethylase 2B
chr2_+_18069375 1.72 ENSMUST00000114671.8
ENSMUST00000114680.9
myeloid/lymphoid or mixed-lineage leukemia; translocated to, 10
chrX_+_35152460 1.70 ENSMUST00000033419.13
dedicator of cytokinesis 11
chr15_+_54274151 1.69 ENSMUST00000036737.4
collectin sub-family member 10
chr4_-_59549243 1.68 ENSMUST00000173699.8
ENSMUST00000173884.8
ENSMUST00000102883.11
ENSMUST00000174586.8
polypyrimidine tract binding protein 3
chr19_-_7318798 1.65 ENSMUST00000165965.8
ENSMUST00000051711.16
ENSMUST00000169541.8
ENSMUST00000165989.2
MAP/microtubule affinity regulating kinase 2
chr12_-_15866763 1.65 ENSMUST00000020922.8
ENSMUST00000221215.2
ENSMUST00000221518.2
tribbles pseudokinase 2
chrX_+_150304137 1.63 ENSMUST00000112670.8
ENSMUST00000046962.11
ENSMUST00000112668.9
ENSMUST00000046950.13
PHD finger protein 8
chr16_-_4698148 1.59 ENSMUST00000037843.7
UBA-like domain containing 1
chr11_+_120123727 1.58 ENSMUST00000122148.8
ENSMUST00000044985.14
BAH domain and coiled-coil containing 1
chr11_+_98632696 1.57 ENSMUST00000103139.11
thyroid hormone receptor alpha
chr17_-_66191912 1.57 ENSMUST00000024905.11
ralA binding protein 1
chr8_+_35274440 1.56 ENSMUST00000033930.5
dual specificity phosphatase 4
chr2_+_112096154 1.56 ENSMUST00000110991.9
solute carrier family 12, member 6
chr17_+_71511642 1.55 ENSMUST00000126681.8
lipin 2
chr19_-_7319211 1.53 ENSMUST00000171393.8
MAP/microtubule affinity regulating kinase 2
chr5_+_86952072 1.51 ENSMUST00000119339.8
ENSMUST00000120498.8
YTH domain containing 1
chr11_-_74480870 1.50 ENSMUST00000145524.2
ENSMUST00000102521.9
RAP1 GTPase activating protein 2
chr3_-_27207931 1.46 ENSMUST00000175857.2
ENSMUST00000177055.8
ENSMUST00000176535.8
ect2 oncogene
chr19_-_45771939 1.45 ENSMUST00000026243.5
O-GlcNAcase
chr14_-_40730180 1.42 ENSMUST00000136661.8
peroxiredoxin like 2A
chr16_-_74208180 1.42 ENSMUST00000117200.8
roundabout guidance receptor 2
chr3_+_102965601 1.41 ENSMUST00000029445.13
ENSMUST00000200069.5
neuroblastoma ras oncogene
chr1_-_54965470 1.38 ENSMUST00000179030.8
ENSMUST00000044359.16
ankyrin repeat domain 44
chr11_+_85243970 1.37 ENSMUST00000108056.8
ENSMUST00000108061.8
ENSMUST00000108062.8
ENSMUST00000138423.8
ENSMUST00000092821.10
ENSMUST00000074875.11
breast carcinoma amplified sequence 3
chr2_-_33321306 1.37 ENSMUST00000113158.8
zinc finger and BTB domain containing 34
chr11_-_54846873 1.37 ENSMUST00000155316.2
ENSMUST00000108889.10
ENSMUST00000126703.8
TNFAIP3 interacting protein 1
chr2_-_71198091 1.36 ENSMUST00000151937.8
solute carrier family 25 (mitochondrial carrier, Aralar), member 12
chr11_-_120881697 1.35 ENSMUST00000154483.8
casein kinase 1, delta
chr13_-_93636224 1.30 ENSMUST00000220513.2
ENSMUST00000065537.9
junction-mediating and regulatory protein
chr19_+_41818409 1.30 ENSMUST00000087155.5
frequently rearranged in advanced T cell lymphomas
chr4_-_129534403 1.30 ENSMUST00000084264.12
taxilin alpha
chr5_-_137529251 1.28 ENSMUST00000132525.8
guanine nucleotide binding protein (G protein), beta 2
chr6_-_5496261 1.27 ENSMUST00000203347.3
ENSMUST00000019721.7
pyruvate dehydrogenase kinase, isoenzyme 4
chr8_-_35962641 1.26 ENSMUST00000033927.8
exoribonuclease 1
chrX_-_7606445 1.26 ENSMUST00000128289.8
coiled-coil domain containing 120
chr4_+_134042423 1.25 ENSMUST00000105875.8
ENSMUST00000030638.7
tripartite motif-containing 63
chr10_-_23112973 1.24 ENSMUST00000218049.2
EYA transcriptional coactivator and phosphatase 4
chr18_+_69652837 1.24 ENSMUST00000201410.4
ENSMUST00000202937.4
transcription factor 4
chr11_-_119977609 1.22 ENSMUST00000106227.8
ENSMUST00000106229.8
ENSMUST00000180242.2
centrosomal protein 131
chr8_-_33374825 1.19 ENSMUST00000238791.2
neuregulin 1
chr7_-_141925947 1.19 ENSMUST00000084412.6
interferon induced transmembrane protein 10
chr10_+_101994841 1.17 ENSMUST00000020039.13
MGAT4 family, member C
chr6_+_54658609 1.17 ENSMUST00000190641.7
ENSMUST00000187701.2
maturin, neural progenitor differentiation regulator homolog (Xenopus)
chr4_+_101365144 1.17 ENSMUST00000149047.8
ENSMUST00000106929.10
DnaJ heat shock protein family (Hsp40) member C6
chr7_-_37472979 1.17 ENSMUST00000176534.8
zinc finger protein 536
chr6_+_29853745 1.15 ENSMUST00000064872.13
ENSMUST00000152581.8
ENSMUST00000176265.8
ENSMUST00000154079.8
S-adenosylhomocysteine hydrolase-like 2
chr3_-_143908111 1.08 ENSMUST00000121796.8
LIM domain only 4
chr15_-_58187556 1.06 ENSMUST00000022985.2
kelch-like 38
chr3_-_51248032 1.05 ENSMUST00000062009.14
ENSMUST00000194641.6
E74-like factor 2
chr11_+_43324547 1.05 ENSMUST00000126128.8
ENSMUST00000151880.8
ENSMUST00000020681.10
SLU7 splicing factor homolog (S. cerevisiae)
chr6_+_34840057 1.04 ENSMUST00000074949.4
transmembrane protein 140
chr2_-_73143045 1.04 ENSMUST00000058615.10
corepressor interacting with RBPJ, 1
chr18_+_69652550 1.03 ENSMUST00000201205.4
transcription factor 4
chr18_+_69652751 1.02 ENSMUST00000200966.4
transcription factor 4
chrX_+_150303650 1.02 ENSMUST00000112666.8
ENSMUST00000112662.9
ENSMUST00000168501.8
PHD finger protein 8
chr7_-_143239600 1.01 ENSMUST00000208017.2
ENSMUST00000152703.2
tumor necrosis factor receptor superfamily, member 23
chrX_+_168468186 1.00 ENSMUST00000112107.8
ENSMUST00000112104.8
midline 1
chr17_-_48189815 1.00 ENSMUST00000154108.2
forkhead box P4
chr12_+_52746158 1.00 ENSMUST00000095737.5
A kinase (PRKA) anchor protein 6
chr7_+_90075762 0.99 ENSMUST00000061391.9
coiled-coil domain containing 89
chr6_-_148847854 0.99 ENSMUST00000139355.8
ENSMUST00000146457.2
ENSMUST00000054080.15
SIN3-HDAC complex associated factor
chr4_+_101365052 0.97 ENSMUST00000038207.12
DnaJ heat shock protein family (Hsp40) member C6
chr3_+_138566249 0.97 ENSMUST00000121826.3
tetraspanin 5
chr11_+_17001818 0.95 ENSMUST00000058159.6
cannabinoid receptor interacting protein 1
chr11_+_98632953 0.95 ENSMUST00000153043.8
thyroid hormone receptor alpha
chr3_-_143908060 0.94 ENSMUST00000121112.6
LIM domain only 4
chr18_+_69652880 0.93 ENSMUST00000200813.4
transcription factor 4
chr17_-_71158703 0.93 ENSMUST00000166395.9
TGFB-induced factor homeobox 1
chr11_+_107438751 0.93 ENSMUST00000100305.8
ENSMUST00000075012.8
ENSMUST00000106746.8
helicase with zinc finger domain
chr18_+_34892599 0.92 ENSMUST00000097622.4
family with sequence similarity 53, member C
chr7_-_44498305 0.91 ENSMUST00000207293.2
ENSMUST00000207532.2
TBC1 domain family, member 17
chr17_+_25105617 0.90 ENSMUST00000117890.8
ENSMUST00000168265.8
ENSMUST00000120943.8
ENSMUST00000068508.13
ENSMUST00000119829.8
splA/ryanodine receptor domain and SOCS box containing 3
chr12_-_86125793 0.90 ENSMUST00000003687.8
transforming growth factor, beta 3
chr14_-_54651442 0.87 ENSMUST00000227334.2
solute carrier family 7 (cationic amino acid transporter, y+ system), member 7
chr4_-_154245073 0.83 ENSMUST00000105639.4
ENSMUST00000030896.15
transformation related protein 63 regulated like
chr19_+_45003670 0.83 ENSMUST00000236377.2
leucine zipper, putative tumor suppressor 2
chr5_-_137529465 0.83 ENSMUST00000150063.9
guanine nucleotide binding protein (G protein), beta 2
chr6_+_34840151 0.82 ENSMUST00000202010.2
transmembrane protein 140
chr17_-_25105277 0.82 ENSMUST00000234583.2
ENSMUST00000234968.2
ENSMUST00000044252.7
nucleotide binding protein 2
chr9_+_56982622 0.82 ENSMUST00000167715.8
transcriptional regulator, SIN3A (yeast)
chr11_+_105072619 0.80 ENSMUST00000092537.10
ENSMUST00000015107.13
ENSMUST00000145048.8
tousled-like kinase 2 (Arabidopsis)
chr13_+_55357585 0.80 ENSMUST00000224973.2
ENSMUST00000099490.3
nuclear receptor-binding SET-domain protein 1
chr2_+_4887015 0.78 ENSMUST00000115019.2
selenophosphate synthetase 1
chr12_+_84463970 0.77 ENSMUST00000183146.2
ring finger protein 113A2
chrX_+_67722390 0.77 ENSMUST00000114654.8
ENSMUST00000114655.8
ENSMUST00000114657.9
ENSMUST00000114653.2
FMRP translational regulator 1
chr18_-_80751327 0.77 ENSMUST00000236310.2
ENSMUST00000167977.8
ENSMUST00000035800.8
nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 1
chr2_+_24866057 0.76 ENSMUST00000153618.8
ENSMUST00000152777.2
patatin-like phospholipase domain containing 7
chr18_+_65713301 0.76 ENSMUST00000049016.12
ENSMUST00000235493.2
ENSMUST00000183236.2
zinc finger protein 532
chr7_+_24607042 0.75 ENSMUST00000151121.2
Rho guanine nucleotide exchange factor (GEF) 1
chr8_-_87472562 0.75 ENSMUST00000045296.6
siah E3 ubiquitin protein ligase 1A
chr13_+_118851214 0.75 ENSMUST00000022246.9
fibroblast growth factor 10
chr1_-_154692678 0.74 ENSMUST00000238369.2
calcium channel, voltage-dependent, R type, alpha 1E subunit

Network of associatons between targets according to the STRING database.

First level regulatory network of Foxd1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
3.9 46.4 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
2.9 8.6 GO:0002270 plasmacytoid dendritic cell activation(GO:0002270)
2.3 58.7 GO:0030213 hyaluronan biosynthetic process(GO:0030213)
1.8 7.1 GO:0090096 lactic acid secretion(GO:0046722) regulation of metanephric cap mesenchymal cell proliferation(GO:0090095) positive regulation of metanephric cap mesenchymal cell proliferation(GO:0090096)
1.5 5.9 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
1.4 5.7 GO:0015827 aromatic amino acid transport(GO:0015801) tryptophan transport(GO:0015827)
1.1 6.8 GO:0002528 regulation of vascular permeability involved in acute inflammatory response(GO:0002528)
1.1 5.5 GO:0010360 negative regulation of anion channel activity(GO:0010360)
1.0 10.1 GO:0032264 IMP salvage(GO:0032264)
1.0 4.0 GO:0021993 initiation of neural tube closure(GO:0021993)
1.0 4.8 GO:0009597 detection of virus(GO:0009597)
0.9 6.1 GO:0015886 heme transport(GO:0015886)
0.7 3.6 GO:0097350 dendritic cell apoptotic process(GO:0097048) neutrophil clearance(GO:0097350) regulation of dendritic cell apoptotic process(GO:2000668)
0.7 2.9 GO:1901301 regulation of cargo loading into COPII-coated vesicle(GO:1901301)
0.7 12.3 GO:1901223 negative regulation of NIK/NF-kappaB signaling(GO:1901223)
0.7 2.8 GO:0070317 negative regulation of G0 to G1 transition(GO:0070317)
0.7 2.7 GO:0061188 histone H4-K20 demethylation(GO:0035574) regulation of chromatin silencing at rDNA(GO:0061187) negative regulation of chromatin silencing at rDNA(GO:0061188)
0.7 18.5 GO:0015701 bicarbonate transport(GO:0015701)
0.6 6.4 GO:2000774 positive regulation of cellular senescence(GO:2000774)
0.6 7.6 GO:1902033 vitamin D receptor signaling pathway(GO:0070561) regulation of hematopoietic stem cell proliferation(GO:1902033)
0.6 2.5 GO:0017055 negative regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0017055)
0.5 1.6 GO:0042091 interleukin-10 biosynthetic process(GO:0042091) regulation of interleukin-10 biosynthetic process(GO:0045074)
0.5 11.5 GO:0051988 regulation of attachment of spindle microtubules to kinetochore(GO:0051988)
0.5 3.1 GO:0097167 circadian regulation of translation(GO:0097167)
0.5 0.5 GO:0002729 positive regulation of natural killer cell cytokine production(GO:0002729)
0.5 2.0 GO:0071544 diphosphoinositol polyphosphate catabolic process(GO:0071544)
0.5 2.0 GO:1904879 positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1904879)
0.5 2.5 GO:0060139 positive regulation by symbiont of host apoptotic process(GO:0052151) positive regulation of apoptotic process by virus(GO:0060139)
0.5 1.9 GO:0090004 positive regulation of Golgi to plasma membrane protein transport(GO:0042998) positive regulation of establishment of protein localization to plasma membrane(GO:0090004)
0.5 1.4 GO:0050925 negative regulation of negative chemotaxis(GO:0050925)
0.4 2.7 GO:0014846 esophagus smooth muscle contraction(GO:0014846)
0.4 4.9 GO:0043553 negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553)
0.4 1.2 GO:0014878 response to electrical stimulus involved in regulation of muscle adaptation(GO:0014878)
0.4 1.6 GO:0042539 hypotonic salinity response(GO:0042539) cellular hypotonic salinity response(GO:0071477)
0.4 4.4 GO:0030916 otic vesicle formation(GO:0030916)
0.4 4.6 GO:0045876 positive regulation of sister chromatid cohesion(GO:0045876)
0.4 1.9 GO:0048014 Tie signaling pathway(GO:0048014)
0.4 1.8 GO:0036023 limb joint morphogenesis(GO:0036022) embryonic skeletal limb joint morphogenesis(GO:0036023)
0.4 2.1 GO:0072318 clathrin coat disassembly(GO:0072318)
0.4 2.8 GO:0097646 calcitonin family receptor signaling pathway(GO:0097646) amylin receptor signaling pathway(GO:0097647)
0.3 1.0 GO:0000389 mRNA 3'-splice site recognition(GO:0000389)
0.3 1.3 GO:0070358 actin polymerization-dependent cell motility(GO:0070358)
0.3 2.6 GO:0033031 positive regulation of neutrophil apoptotic process(GO:0033031)
0.3 1.3 GO:0010510 regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510)
0.3 1.6 GO:1903378 positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903378)
0.3 0.9 GO:0003032 detection of oxygen(GO:0003032)
0.3 2.8 GO:2000741 positive regulation of mesenchymal stem cell differentiation(GO:2000741)
0.3 4.1 GO:0072600 establishment of protein localization to Golgi(GO:0072600)
0.3 1.4 GO:0043490 malate-aspartate shuttle(GO:0043490)
0.3 2.1 GO:0045084 positive regulation of interleukin-12 biosynthetic process(GO:0045084)
0.3 0.8 GO:0060854 patterning of lymph vessels(GO:0060854)
0.2 1.0 GO:1901250 regulation of lung goblet cell differentiation(GO:1901249) negative regulation of lung goblet cell differentiation(GO:1901250)
0.2 4.4 GO:0021527 spinal cord association neuron differentiation(GO:0021527)
0.2 7.2 GO:0032060 bleb assembly(GO:0032060)
0.2 0.8 GO:1901675 negative regulation of histone H3-K27 acetylation(GO:1901675)
0.2 2.4 GO:0019368 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.2 1.0 GO:2000481 positive regulation of cAMP-dependent protein kinase activity(GO:2000481)
0.2 0.6 GO:0035526 retrograde transport, plasma membrane to Golgi(GO:0035526)
0.2 5.5 GO:0003417 growth plate cartilage development(GO:0003417)
0.2 0.8 GO:0051182 coenzyme transport(GO:0051182)
0.2 1.6 GO:0021842 directional guidance of interneurons involved in migration from the subpallium to the cortex(GO:0021840) chemorepulsion involved in interneuron migration from the subpallium to the cortex(GO:0021842)
0.2 6.7 GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
0.2 1.2 GO:0035735 intraciliary transport involved in cilium morphogenesis(GO:0035735)
0.2 6.1 GO:0006270 DNA replication initiation(GO:0006270)
0.2 1.8 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.2 2.6 GO:0033148 positive regulation of intracellular estrogen receptor signaling pathway(GO:0033148)
0.2 14.9 GO:0006611 protein export from nucleus(GO:0006611)
0.2 2.7 GO:0050930 induction of positive chemotaxis(GO:0050930)
0.2 11.0 GO:0045604 regulation of epidermal cell differentiation(GO:0045604)
0.2 1.4 GO:1903003 positive regulation of protein deubiquitination(GO:1903003)
0.1 0.4 GO:0021569 rhombomere 3 development(GO:0021569) rhombomere 4 development(GO:0021570) rhombomere 5 development(GO:0021571)
0.1 2.5 GO:0019374 cellular defense response(GO:0006968) galactolipid metabolic process(GO:0019374)
0.1 0.9 GO:0000821 regulation of arginine metabolic process(GO:0000821)
0.1 1.2 GO:0033353 S-adenosylmethionine cycle(GO:0033353)
0.1 1.7 GO:0002315 marginal zone B cell differentiation(GO:0002315)
0.1 2.5 GO:0061179 negative regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061179)
0.1 2.4 GO:0071243 cellular response to arsenic-containing substance(GO:0071243)
0.1 1.3 GO:0031125 rRNA 3'-end processing(GO:0031125)
0.1 1.5 GO:0043249 erythrocyte maturation(GO:0043249)
0.1 0.9 GO:0001672 regulation of chromatin assembly or disassembly(GO:0001672)
0.1 0.8 GO:0043144 snoRNA processing(GO:0043144)
0.1 2.2 GO:2001256 regulation of store-operated calcium entry(GO:2001256)
0.1 0.3 GO:0061343 cell adhesion involved in heart morphogenesis(GO:0061343)
0.1 2.9 GO:0042118 endothelial cell activation(GO:0042118)
0.1 0.8 GO:0032876 negative regulation of DNA endoreduplication(GO:0032876)
0.1 1.0 GO:0035372 protein localization to microtubule(GO:0035372)
0.1 2.7 GO:0010592 positive regulation of lamellipodium assembly(GO:0010592)
0.1 0.3 GO:0044029 DNA hypomethylation(GO:0044028) hypomethylation of CpG island(GO:0044029)
0.1 1.4 GO:2000251 positive regulation of actin cytoskeleton reorganization(GO:2000251)
0.1 0.6 GO:0098532 histone H3-K27 trimethylation(GO:0098532)
0.1 0.8 GO:0000414 regulation of histone H3-K36 methylation(GO:0000414)
0.1 8.4 GO:0045576 mast cell activation(GO:0045576)
0.1 2.4 GO:2001224 positive regulation of neuron migration(GO:2001224)
0.1 2.7 GO:0002347 response to tumor cell(GO:0002347)
0.1 5.3 GO:0045197 establishment or maintenance of epithelial cell apical/basal polarity(GO:0045197)
0.1 1.4 GO:0034067 protein localization to Golgi apparatus(GO:0034067)
0.1 0.7 GO:0018243 protein O-linked glycosylation via threonine(GO:0018243)
0.1 1.2 GO:0016576 histone dephosphorylation(GO:0016576)
0.1 0.7 GO:0090273 regulation of somatostatin secretion(GO:0090273)
0.1 2.9 GO:0048268 clathrin coat assembly(GO:0048268)
0.1 0.3 GO:0060005 vestibular reflex(GO:0060005)
0.1 2.5 GO:0090162 establishment of epithelial cell polarity(GO:0090162)
0.1 1.6 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.1 0.5 GO:0002887 negative regulation of myeloid leukocyte mediated immunity(GO:0002887) negative regulation of neutrophil degranulation(GO:0043314) negative regulation of blood vessel remodeling(GO:0060313) negative regulation of neutrophil activation(GO:1902564)
0.1 0.8 GO:0043922 negative regulation by host of viral transcription(GO:0043922)
0.1 0.8 GO:0045947 negative regulation of translational initiation(GO:0045947)
0.1 3.2 GO:1900047 negative regulation of blood coagulation(GO:0030195) negative regulation of hemostasis(GO:1900047)
0.1 4.8 GO:0038083 peptidyl-tyrosine autophosphorylation(GO:0038083)
0.1 2.3 GO:0006471 protein ADP-ribosylation(GO:0006471)
0.1 2.4 GO:0045907 positive regulation of vasoconstriction(GO:0045907)
0.0 0.3 GO:0097368 establishment of Sertoli cell barrier(GO:0097368)
0.0 0.2 GO:0019858 cytosine metabolic process(GO:0019858)
0.0 4.3 GO:0021510 spinal cord development(GO:0021510)
0.0 1.0 GO:0071425 hematopoietic stem cell proliferation(GO:0071425)
0.0 0.8 GO:0031163 iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
0.0 0.7 GO:0097264 self proteolysis(GO:0097264)
0.0 0.9 GO:0038092 nodal signaling pathway(GO:0038092)
0.0 1.0 GO:0045747 positive regulation of Notch signaling pathway(GO:0045747)
0.0 1.5 GO:0006376 mRNA splice site selection(GO:0006376)
0.0 0.5 GO:0031507 heterochromatin assembly(GO:0031507)
0.0 0.2 GO:0043578 nuclear matrix organization(GO:0043578) nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.0 0.5 GO:0007202 activation of phospholipase C activity(GO:0007202)
0.0 1.4 GO:0010107 potassium ion import(GO:0010107)
0.0 0.3 GO:0060136 embryonic process involved in female pregnancy(GO:0060136)
0.0 0.7 GO:0007141 male meiosis I(GO:0007141)
0.0 1.5 GO:0019432 triglyceride biosynthetic process(GO:0019432)
0.0 0.2 GO:0019348 dolichol metabolic process(GO:0019348)
0.0 0.7 GO:0001553 luteinization(GO:0001553)
0.0 1.0 GO:1902042 negative regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902042)
0.0 0.1 GO:0090245 axis elongation involved in somitogenesis(GO:0090245)
0.0 1.7 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.0 0.5 GO:0021796 cerebral cortex regionalization(GO:0021796)
0.0 0.6 GO:0050901 leukocyte tethering or rolling(GO:0050901)
0.0 0.3 GO:0051967 negative regulation of synaptic transmission, glutamatergic(GO:0051967)
0.0 0.6 GO:0006891 intra-Golgi vesicle-mediated transport(GO:0006891)
0.0 0.2 GO:0048935 peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.0 1.0 GO:0042147 retrograde transport, endosome to Golgi(GO:0042147)
0.0 3.3 GO:0000398 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile(GO:0000377) mRNA splicing, via spliceosome(GO:0000398)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
2.9 46.4 GO:0042555 MCM complex(GO:0042555)
2.5 7.5 GO:0036398 TCR signalosome(GO:0036398)
2.0 6.1 GO:0097135 cyclin E2-CDK2 complex(GO:0097135)
2.0 5.9 GO:0005588 collagen type V trimer(GO:0005588)
1.9 11.5 GO:0097149 centralspindlin complex(GO:0097149)
0.8 58.7 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.7 2.7 GO:0098833 presynaptic endocytic zone(GO:0098833) presynaptic endocytic zone membrane(GO:0098835)
0.7 4.6 GO:0000798 nuclear cohesin complex(GO:0000798)
0.5 6.0 GO:0097427 microtubule bundle(GO:0097427)
0.3 2.3 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
0.3 2.5 GO:0061689 tricellular tight junction(GO:0061689)
0.2 0.8 GO:0014701 junctional sarcoplasmic reticulum membrane(GO:0014701)
0.2 2.5 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.2 2.7 GO:0031209 SCAR complex(GO:0031209)
0.2 3.6 GO:0033643 host(GO:0018995) host cell part(GO:0033643) host cell(GO:0043657)
0.2 2.9 GO:0030127 COPII vesicle coat(GO:0030127)
0.2 1.3 GO:0071204 histone pre-mRNA 3'end processing complex(GO:0071204)
0.1 18.5 GO:0014704 intercalated disc(GO:0014704)
0.1 7.1 GO:0005719 nuclear euchromatin(GO:0005719)
0.1 14.9 GO:0005643 nuclear pore(GO:0005643)
0.1 2.0 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.1 1.2 GO:0002177 manchette(GO:0002177)
0.1 2.5 GO:0042589 zymogen granule membrane(GO:0042589)
0.1 0.3 GO:0005943 phosphatidylinositol 3-kinase complex, class IA(GO:0005943)
0.1 7.5 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.1 17.4 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)
0.1 2.6 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.1 1.4 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.1 9.5 GO:0071013 catalytic step 2 spliceosome(GO:0071013)
0.1 3.1 GO:0030673 axolemma(GO:0030673)
0.1 2.4 GO:0031430 M band(GO:0031430)
0.1 4.1 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 0.2 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.0 0.5 GO:0005677 chromatin silencing complex(GO:0005677)
0.0 7.2 GO:0032993 protein-DNA complex(GO:0032993)
0.0 1.0 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.0 0.8 GO:0016580 Sin3 complex(GO:0016580)
0.0 6.3 GO:0031234 extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.0 0.8 GO:0031616 spindle pole centrosome(GO:0031616)
0.0 0.3 GO:0032983 kainate selective glutamate receptor complex(GO:0032983)
0.0 2.8 GO:0000118 histone deacetylase complex(GO:0000118)
0.0 2.7 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.0 0.8 GO:0005684 U2-type spliceosomal complex(GO:0005684)
0.0 0.5 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
0.0 0.6 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 1.4 GO:0005876 spindle microtubule(GO:0005876)
0.0 2.5 GO:0031903 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.0 1.9 GO:0009925 basal plasma membrane(GO:0009925)
0.0 7.0 GO:0072562 blood microparticle(GO:0072562)
0.0 0.6 GO:0045335 phagocytic vesicle(GO:0045335)
0.0 4.3 GO:0005769 early endosome(GO:0005769)
0.0 0.2 GO:0034992 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0 6.6 GO:0016607 nuclear speck(GO:0016607)
0.0 0.8 GO:0031519 PcG protein complex(GO:0031519)
0.0 1.0 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.0 0.8 GO:0035097 histone methyltransferase complex(GO:0035097)
0.0 0.9 GO:0030315 T-tubule(GO:0030315)
0.0 4.1 GO:0044306 neuron projection terminus(GO:0044306)
0.0 5.1 GO:0031252 cell leading edge(GO:0031252)
0.0 3.5 GO:0031965 nuclear membrane(GO:0031965)
0.0 5.6 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.0 2.9 GO:0043209 myelin sheath(GO:0043209)
0.0 2.7 GO:0010008 endosome membrane(GO:0010008)
0.0 1.9 GO:0005802 trans-Golgi network(GO:0005802)
0.0 0.6 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.0 2.0 GO:0016323 basolateral plasma membrane(GO:0016323)
0.0 9.4 GO:0009986 cell surface(GO:0009986)
0.0 0.9 GO:0005882 intermediate filament(GO:0005882)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
2.9 8.6 GO:0000401 open form four-way junction DNA binding(GO:0000401) crossed form four-way junction DNA binding(GO:0000402)
1.9 9.3 GO:0097003 adipokinetic hormone receptor activity(GO:0097003)
1.2 4.9 GO:0036313 phosphatidylinositol 3-kinase catalytic subunit binding(GO:0036313)
1.1 14.9 GO:0005049 nuclear export signal receptor activity(GO:0005049)
1.1 5.5 GO:0047696 beta-adrenergic receptor kinase activity(GO:0047696)
1.1 46.4 GO:0004003 ATP-dependent DNA helicase activity(GO:0004003)
1.0 6.1 GO:0015232 heme transporter activity(GO:0015232)
1.0 58.7 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
1.0 10.1 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
1.0 5.7 GO:0008241 peptidyl-dipeptidase activity(GO:0008241)
0.8 18.5 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.8 2.5 GO:0042282 hydroxymethylglutaryl-CoA reductase (NADPH) activity(GO:0004420) hydroxymethylglutaryl-CoA reductase activity(GO:0042282)
0.8 6.6 GO:0005499 vitamin D binding(GO:0005499)
0.8 6.8 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.7 2.7 GO:0035575 histone demethylase activity (H4-K20 specific)(GO:0035575)
0.6 7.6 GO:0043024 ribosomal small subunit binding(GO:0043024)
0.6 2.5 GO:0002153 steroid receptor RNA activator RNA binding(GO:0002153)
0.5 1.6 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.5 1.4 GO:0010698 acetyltransferase activator activity(GO:0010698)
0.4 1.6 GO:0035827 rubidium ion transmembrane transporter activity(GO:0035827)
0.4 7.3 GO:0050321 tau-protein kinase activity(GO:0050321)
0.4 2.7 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.4 4.8 GO:0022889 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.3 1.0 GO:0000386 second spliceosomal transesterification activity(GO:0000386)
0.3 1.4 GO:0015183 L-aspartate transmembrane transporter activity(GO:0015183)
0.3 1.3 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.3 1.3 GO:0071207 histone pre-mRNA stem-loop binding(GO:0071207)
0.3 2.0 GO:0000298 endopolyphosphatase activity(GO:0000298) diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) bis(5'-adenosyl)-hexaphosphatase activity(GO:0034431) bis(5'-adenosyl)-pentaphosphatase activity(GO:0034432)
0.3 2.0 GO:0086056 voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056)
0.3 0.8 GO:0016781 selenide, water dikinase activity(GO:0004756) phosphotransferase activity, paired acceptors(GO:0016781)
0.3 4.0 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.2 2.8 GO:0052813 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol bisphosphate kinase activity(GO:0052813)
0.2 2.7 GO:0042609 CD4 receptor binding(GO:0042609)
0.2 2.4 GO:0102337 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.2 3.6 GO:0032036 myosin heavy chain binding(GO:0032036)
0.2 2.9 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.2 6.1 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.2 1.2 GO:0016802 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.2 2.4 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.2 1.9 GO:0071253 connexin binding(GO:0071253)
0.2 1.6 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.2 2.4 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.2 2.5 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.2 0.8 GO:0001225 RNA polymerase II transcription coactivator binding(GO:0001225)
0.2 0.9 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
0.1 1.4 GO:0008046 axon guidance receptor activity(GO:0008046)
0.1 1.5 GO:1990247 N6-methyladenosine-containing RNA binding(GO:1990247)
0.1 3.8 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.1 0.5 GO:0005134 interleukin-2 receptor binding(GO:0005134)
0.1 3.0 GO:0032041 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.1 5.9 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.1 2.0 GO:0045499 chemorepellent activity(GO:0045499)
0.1 0.8 GO:0042799 histone methyltransferase activity (H4-K20 specific)(GO:0042799)
0.1 2.2 GO:0030215 semaphorin receptor binding(GO:0030215)
0.1 0.7 GO:0005111 type 2 fibroblast growth factor receptor binding(GO:0005111)
0.1 7.0 GO:0008186 RNA helicase activity(GO:0003724) ATP-dependent RNA helicase activity(GO:0004004) RNA-dependent ATPase activity(GO:0008186)
0.1 2.4 GO:0005523 tropomyosin binding(GO:0005523)
0.1 1.3 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.1 14.8 GO:0017048 Rho GTPase binding(GO:0017048)
0.1 5.2 GO:0070888 E-box binding(GO:0070888)
0.1 1.2 GO:0031432 titin binding(GO:0031432)
0.1 4.1 GO:0005246 calcium channel regulator activity(GO:0005246)
0.1 6.3 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.1 0.4 GO:0004719 protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
0.1 6.5 GO:0045309 protein phosphorylated amino acid binding(GO:0045309)
0.1 2.8 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.1 1.6 GO:0005537 mannose binding(GO:0005537)
0.1 4.4 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.1 0.8 GO:0090482 vitamin transmembrane transporter activity(GO:0090482)
0.1 0.6 GO:0046976 histone methyltransferase activity (H3-K27 specific)(GO:0046976)
0.1 1.5 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.1 1.0 GO:0043495 protein anchor(GO:0043495)
0.1 8.8 GO:0005178 integrin binding(GO:0005178)
0.0 0.2 GO:0003976 UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity(GO:0003976)
0.0 2.7 GO:0001786 phosphatidylserine binding(GO:0001786)
0.0 0.7 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.0 0.3 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.0 0.9 GO:0015174 basic amino acid transmembrane transporter activity(GO:0015174)
0.0 2.3 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 0.9 GO:0070410 co-SMAD binding(GO:0070410)
0.0 1.4 GO:0070840 dynein complex binding(GO:0070840)
0.0 0.7 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.0 1.4 GO:0005242 inward rectifier potassium channel activity(GO:0005242)
0.0 2.3 GO:0019003 GDP binding(GO:0019003)
0.0 0.8 GO:0004407 histone deacetylase activity(GO:0004407)
0.0 0.7 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0 1.4 GO:0051019 mitogen-activated protein kinase binding(GO:0051019)
0.0 4.8 GO:0017124 SH3 domain binding(GO:0017124)
0.0 0.2 GO:0070579 methylcytosine dioxygenase activity(GO:0070579)
0.0 0.6 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0 0.5 GO:0017166 vinculin binding(GO:0017166)
0.0 0.8 GO:0051539 4 iron, 4 sulfur cluster binding(GO:0051539)
0.0 0.2 GO:0052744 phosphatidylinositol-3-phosphatase activity(GO:0004438) phosphatidylinositol monophosphate phosphatase activity(GO:0052744)
0.0 0.2 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.0 1.3 GO:0019905 syntaxin binding(GO:0019905)
0.0 1.0 GO:0051219 phosphoprotein binding(GO:0051219)
0.0 3.5 GO:0003924 GTPase activity(GO:0003924)
0.0 0.7 GO:0017080 sodium channel regulator activity(GO:0017080)
0.0 2.0 GO:0047485 protein N-terminus binding(GO:0047485)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 66.1 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.9 14.9 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.8 45.6 PID ATR PATHWAY ATR signaling pathway
0.5 7.6 PID IL5 PATHWAY IL5-mediated signaling events
0.4 6.1 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.2 8.6 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.2 12.3 PID PLK1 PATHWAY PLK1 signaling events
0.2 3.7 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.2 10.7 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.2 2.5 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.2 2.6 SA TRKA RECEPTOR The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.1 11.2 PID E2F PATHWAY E2F transcription factor network
0.1 5.9 NABA COLLAGENS Genes encoding collagen proteins
0.1 3.3 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.1 5.3 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.1 9.1 WNT SIGNALING Genes related to Wnt-mediated signal transduction
0.1 2.8 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.1 6.0 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network
0.1 2.7 PID ECADHERIN NASCENT AJ PATHWAY E-cadherin signaling in the nascent adherens junction
0.0 2.9 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.0 1.4 ST ERK1 ERK2 MAPK PATHWAY ERK1/ERK2 MAPK Pathway
0.0 0.6 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.0 3.8 PID AR PATHWAY Coregulation of Androgen receptor activity
0.0 3.8 PID HDAC CLASSI PATHWAY Signaling events mediated by HDAC Class I
0.0 3.1 PID NOTCH PATHWAY Notch signaling pathway
0.0 6.8 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 0.9 PID GLYPICAN 1PATHWAY Glypican 1 network
0.0 0.5 PID RB 1PATHWAY Regulation of retinoblastoma protein
0.0 7.1 NABA SECRETED FACTORS Genes encoding secreted soluble factors
0.0 1.8 PID RHOA REG PATHWAY Regulation of RhoA activity

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
2.9 46.4 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.9 58.7 REACTOME G1 PHASE Genes involved in G1 Phase
0.7 8.6 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.4 10.1 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.4 14.9 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
0.3 6.4 REACTOME CTNNB1 PHOSPHORYLATION CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.3 6.7 REACTOME PROLACTIN RECEPTOR SIGNALING Genes involved in Prolactin receptor signaling
0.2 8.4 REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.2 4.5 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1
0.2 1.6 REACTOME ERKS ARE INACTIVATED Genes involved in ERKs are inactivated
0.2 3.9 REACTOME RAF MAP KINASE CASCADE Genes involved in RAF/MAP kinase cascade
0.2 2.7 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.1 7.8 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.1 2.9 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.1 13.6 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.1 7.9 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.1 1.6 REACTOME SHC1 EVENTS IN ERBB4 SIGNALING Genes involved in SHC1 events in ERBB4 signaling
0.1 1.2 REACTOME CIRCADIAN CLOCK Genes involved in Circadian Clock
0.1 2.8 REACTOME AMYLOIDS Genes involved in Amyloids
0.1 5.6 REACTOME MEIOTIC SYNAPSIS Genes involved in Meiotic Synapsis
0.1 4.1 REACTOME G BETA GAMMA SIGNALLING THROUGH PLC BETA Genes involved in G beta:gamma signalling through PLC beta
0.1 2.6 REACTOME REGULATION OF SIGNALING BY CBL Genes involved in Regulation of signaling by CBL
0.1 1.3 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.1 1.8 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.1 13.7 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.1 2.1 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.1 2.5 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.1 2.2 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.1 1.5 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.1 2.4 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.1 1.6 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.1 9.6 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.1 3.0 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.1 2.1 REACTOME LYSOSOME VESICLE BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis
0.1 1.4 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0 1.5 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.0 2.9 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 0.6 REACTOME SIGNALING BY FGFR1 MUTANTS Genes involved in Signaling by FGFR1 mutants
0.0 1.2 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.0 0.8 REACTOME G ALPHA1213 SIGNALLING EVENTS Genes involved in G alpha (12/13) signalling events
0.0 0.4 REACTOME ACTIVATION OF CHAPERONES BY ATF6 ALPHA Genes involved in Activation of Chaperones by ATF6-alpha
0.0 1.4 REACTOME GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.0 0.7 REACTOME FGFR1 LIGAND BINDING AND ACTIVATION Genes involved in FGFR1 ligand binding and activation
0.0 0.3 REACTOME ACTIVATION OF KAINATE RECEPTORS UPON GLUTAMATE BINDING Genes involved in Activation of Kainate Receptors upon glutamate binding
0.0 0.2 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.0 4.4 REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.0 0.8 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.0 0.5 REACTOME CHONDROITIN SULFATE DERMATAN SULFATE METABOLISM Genes involved in Chondroitin sulfate/dermatan sulfate metabolism