ISMARA results: Foxp2

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GSE58827: Dynamics of the Mouse Liver

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Results for Foxp2_Foxp3

Z-value: 0.63

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Transcription factors associated with Foxp2_Foxp3

Gene Symbol	Gene ID	Gene Info
Foxp2 Ensembl NCBI MGI UniProt	ENSMUSG00000029563.17	forkhead box P2
Foxp3 Ensembl NCBI MGI UniProt	ENSMUSG00000039521.14	forkhead box P3

Activity-expression correlation:

Gene	Promoter	Pearson corr. coef.	P-value	Plot
Foxp3	mm39_v1_chrX_+_7446721_7446732	-0.57	3.1e-04	Click!
Foxp2	mm39_v1_chr6_+_14901439_14901531	0.15	4.0e-01	Click!

Activity profile of Foxp2_Foxp3 motif

Sorted Z-values of Foxp2_Foxp3 motif

Top targets:

Promoter	Log-likelihood	Transcript	Gene	Gene Info
chr1_-_130589321 Show fit	5.68	ENSMUST00000137276.3	C4bp Ensembl NCBI MGI UniProt Show fit	complement component 4 binding protein
chr1_-_130589349 Show fit	5.61	ENSMUST00000027657.14	C4bp Ensembl NCBI MGI UniProt Show fit	complement component 4 binding protein
chr11_+_69945157 Show fit	5.53	ENSMUST00000108585.9 ENSMUST00000018699.13	Asgr1 Ensembl NCBI MGI UniProt Show fit	asialoglycoprotein receptor 1
chr6_+_121323577 Show fit	4.89	ENSMUST00000032200.16	Slc6a12 Ensembl NCBI MGI UniProt Show fit	solute carrier family 6 (neurotransmitter transporter, betaine/GABA), member 12
chr7_+_140343652 Show fit	4.78	ENSMUST00000026552.9 ENSMUST00000209253.2 ENSMUST00000210235.2	Cyp2e1 Ensembl NCBI MGI UniProt Show fit	cytochrome P450, family 2, subfamily e, polypeptide 1
chr14_-_52150804 Show fit	4.68	ENSMUST00000004673.15 ENSMUST00000111632.5	Ndrg2 Ensembl NCBI MGI UniProt Show fit	N-myc downstream regulated gene 2
chr5_-_145816774 Show fit	4.55	ENSMUST00000035918.8	Cyp3a11 Ensembl NCBI MGI UniProt Show fit	cytochrome P450, family 3, subfamily a, polypeptide 11
chr19_+_30210320 Show fit	4.42	ENSMUST00000025797.7	Mbl2 Ensembl NCBI MGI UniProt Show fit	mannose-binding lectin (protein C) 2
chr1_-_180023518 Show fit	4.19	ENSMUST00000162769.8 ENSMUST00000161379.2 ENSMUST00000027766.13 ENSMUST00000161814.8	Coq8a Ensembl NCBI MGI UniProt Show fit	coenzyme Q8A
chr1_-_180023467 Show fit	4.13	ENSMUST00000161746.2 ENSMUST00000160879.7	Coq8a Ensembl NCBI MGI UniProt Show fit	coenzyme Q8A
chr14_-_52151537 Show fit	4.12	ENSMUST00000227402.2 ENSMUST00000227237.2	Ndrg2 Ensembl NCBI MGI UniProt Show fit	N-myc downstream regulated gene 2
chr14_-_52151026 Show fit	4.03	ENSMUST00000228164.2	Ndrg2 Ensembl NCBI MGI UniProt Show fit	N-myc downstream regulated gene 2
chr10_+_93324624 Show fit	3.98	ENSMUST00000129421.8	Hal Ensembl NCBI MGI UniProt Show fit	histidine ammonia lyase
chr5_+_90708962 Show fit	3.91	ENSMUST00000094615.8 ENSMUST00000200765.2	Albfm1 Ensembl NCBI MGI UniProt Show fit	albumin superfamily member 1
chr2_-_134396268 Show fit	3.88	ENSMUST00000028704.3	Hao1 Ensembl NCBI MGI UniProt Show fit	hydroxyacid oxidase 1, liver
chr15_-_78352801 Show fit	3.60	ENSMUST00000229124.2 ENSMUST00000230226.2 ENSMUST00000017086.5	Tmprss6 Ensembl NCBI MGI UniProt Show fit	transmembrane serine protease 6
chr14_+_55798362 Show fit	3.57	ENSMUST00000072530.11 ENSMUST00000128490.9	Dcaf11 Ensembl NCBI MGI UniProt Show fit	DDB1 and CUL4 associated factor 11
chr17_-_12894716 Show fit	3.55	ENSMUST00000024596.10	Slc22a1 Ensembl NCBI MGI UniProt Show fit	solute carrier family 22 (organic cation transporter), member 1
chr11_+_70104929 Show fit	3.53	ENSMUST00000094055.10 ENSMUST00000126296.8 ENSMUST00000136328.2 ENSMUST00000153993.3	Slc16a11 Ensembl NCBI MGI UniProt Show fit	solute carrier family 16 (monocarboxylic acid transporters), member 11
chr14_+_55797934 Show fit	3.52	ENSMUST00000121622.8 ENSMUST00000143431.2 ENSMUST00000150481.8	Dcaf11 Ensembl NCBI MGI UniProt Show fit	DDB1 and CUL4 associated factor 11
chr9_+_46179899 Show fit	3.43	ENSMUST00000121598.8	Apoa5 Ensembl NCBI MGI UniProt Show fit	apolipoprotein A-V
chr11_+_69983459 Show fit	3.21	ENSMUST00000102572.8	Asgr2 Ensembl NCBI MGI UniProt Show fit	asialoglycoprotein receptor 2
chr11_+_69983531 Show fit	3.14	ENSMUST00000124721.2	Asgr2 Ensembl NCBI MGI UniProt Show fit	asialoglycoprotein receptor 2
chr11_+_69983479 Show fit	3.09	ENSMUST00000143772.8	Asgr2 Ensembl NCBI MGI UniProt Show fit	asialoglycoprotein receptor 2
chr14_+_55798517 Show fit	3.06	ENSMUST00000117701.8	Dcaf11 Ensembl NCBI MGI UniProt Show fit	DDB1 and CUL4 associated factor 11
chr6_+_116627567 Show fit	3.04	ENSMUST00000067354.10 ENSMUST00000178241.4	Depp1 Ensembl NCBI MGI UniProt Show fit	DEPP1 autophagy regulator
chr11_+_78389913 Show fit	2.94	ENSMUST00000017488.5	Vtn Ensembl NCBI MGI UniProt Show fit	vitronectin
chr4_+_144619647 Show fit	2.86	ENSMUST00000154208.8	Dhrs3 Ensembl NCBI MGI UniProt Show fit	dehydrogenase/reductase (SDR family) member 3
chr2_+_58645189 Show fit	2.82	ENSMUST00000102755.4 ENSMUST00000230627.2 ENSMUST00000229923.2	Upp2 Ensembl NCBI MGI UniProt Show fit	uridine phosphorylase 2
chr15_+_99290832 Show fit	2.79	ENSMUST00000160635.8 ENSMUST00000161250.8 ENSMUST00000229392.2 ENSMUST00000161778.8	Tmbim6 Ensembl NCBI MGI UniProt Show fit	transmembrane BAX inhibitor motif containing 6
chr4_+_144619696 Show fit	2.76	ENSMUST00000142808.8	Dhrs3 Ensembl NCBI MGI UniProt Show fit	dehydrogenase/reductase (SDR family) member 3
chr4_+_144619397 Show fit	2.71	ENSMUST00000105744.8 ENSMUST00000171001.8	Dhrs3 Ensembl NCBI MGI UniProt Show fit	dehydrogenase/reductase (SDR family) member 3
chr5_-_87716882 Show fit	2.70	ENSMUST00000113314.3	Sult1d1 Ensembl NCBI MGI UniProt Show fit	sulfotransferase family 1D, member 1
chr11_+_108286114 Show fit	2.67	ENSMUST00000000049.6	Apoh Ensembl NCBI MGI UniProt Show fit	apolipoprotein H
chr4_+_138181616 Show fit	2.67	ENSMUST00000050918.4	Camk2n1 Ensembl NCBI MGI UniProt Show fit	calcium/calmodulin-dependent protein kinase II inhibitor 1
chr15_+_3300249 Show fit	2.65	ENSMUST00000082424.12 ENSMUST00000159158.9 ENSMUST00000159216.10 ENSMUST00000160311.3	Selenop Ensembl NCBI MGI UniProt Show fit	selenoprotein P
chr15_+_99291100 Show fit	2.64	ENSMUST00000159209.8	Tmbim6 Ensembl NCBI MGI UniProt Show fit	transmembrane BAX inhibitor motif containing 6
chrX_+_138701544 Show fit	2.63	ENSMUST00000054889.4	Cldn2 Ensembl NCBI MGI UniProt Show fit	claudin 2
chrX_+_100419965 Show fit	2.60	ENSMUST00000119080.8	Gjb1 Ensembl NCBI MGI UniProt Show fit	gap junction protein, beta 1
chr6_+_30541581 Show fit	2.60	ENSMUST00000096066.5	Cpa2 Ensembl NCBI MGI UniProt Show fit	carboxypeptidase A2, pancreatic
chr6_+_116627635 Show fit	2.55	ENSMUST00000204555.2	Depp1 Ensembl NCBI MGI UniProt Show fit	DEPP1 autophagy regulator
chr18_-_39051695 Show fit	2.55	ENSMUST00000040647.11	Fgf1 Ensembl NCBI MGI UniProt Show fit	fibroblast growth factor 1
chrX_-_7547273 Show fit	2.51	ENSMUST00000115695.4	Magix Ensembl NCBI MGI UniProt Show fit	MAGI family member, X-linked
chr8_-_122671588 Show fit	2.49	ENSMUST00000057653.8	Car5a Ensembl NCBI MGI UniProt Show fit	carbonic anhydrase 5a, mitochondrial
chr1_-_162726234 Show fit	2.42	ENSMUST00000111510.8 ENSMUST00000045902.13	Fmo2 Ensembl NCBI MGI UniProt Show fit	flavin containing monooxygenase 2
chr11_-_86884507 Show fit	2.38	ENSMUST00000018571.5	Ypel2 Ensembl NCBI MGI UniProt Show fit	yippee like 2
chr4_+_133280680 Show fit	2.37	ENSMUST00000042706.3	Nr0b2 Ensembl NCBI MGI UniProt Show fit	nuclear receptor subfamily 0, group B, member 2
chr2_+_58644922 Show fit	2.32	ENSMUST00000059102.13	Upp2 Ensembl NCBI MGI UniProt Show fit	uridine phosphorylase 2
chr1_+_130793406 Show fit	2.31	ENSMUST00000038829.7	Fcmr Ensembl NCBI MGI UniProt Show fit	Fc fragment of IgM receptor
chr10_+_87695352 Show fit	2.30	ENSMUST00000121952.8 ENSMUST00000126490.8	Igf1 Ensembl NCBI MGI UniProt Show fit	insulin-like growth factor 1
chr10_-_89369432 Show fit	2.29	ENSMUST00000105297.2	Nr1h4 Ensembl NCBI MGI UniProt Show fit	nuclear receptor subfamily 1, group H, member 4
chr11_+_70104736 Show fit	2.29	ENSMUST00000171032.8	Slc16a11 Ensembl NCBI MGI UniProt Show fit	solute carrier family 16 (monocarboxylic acid transporters), member 11
chr12_-_103871146 Show fit	2.11	ENSMUST00000074051.6	Serpina1c Ensembl NCBI MGI UniProt Show fit	serine (or cysteine) peptidase inhibitor, clade A, member 1C
chr12_-_81014849 Show fit	2.09	ENSMUST00000095572.5	Slc10a1 Ensembl NCBI MGI UniProt Show fit	solute carrier family 10 (sodium/bile acid cotransporter family), member 1
chr12_-_84497718 Show fit	2.07	ENSMUST00000085192.7 ENSMUST00000220491.2	Aldh6a1 Ensembl NCBI MGI UniProt Show fit	aldehyde dehydrogenase family 6, subfamily A1
chr1_+_171052623 Show fit	2.04	ENSMUST00000111321.8 ENSMUST00000005824.12 ENSMUST00000111320.8 ENSMUST00000111319.2	Apoa2 Ensembl NCBI MGI UniProt Show fit	apolipoprotein A-II
chr2_-_110136074 Show fit	2.02	ENSMUST00000046233.9	Bbox1 Ensembl NCBI MGI UniProt Show fit	butyrobetaine (gamma), 2-oxoglutarate dioxygenase 1 (gamma-butyrobetaine hydroxylase)
chr12_-_81014755 Show fit	1.99	ENSMUST00000218342.2	Slc10a1 Ensembl NCBI MGI UniProt Show fit	solute carrier family 10 (sodium/bile acid cotransporter family), member 1
chr14_-_31362835 Show fit	1.96	ENSMUST00000167066.8 ENSMUST00000127204.9	Hacl1 Ensembl NCBI MGI UniProt Show fit	2-hydroxyacyl-CoA lyase 1
chr11_+_114741948 Show fit	1.91	ENSMUST00000133245.2 ENSMUST00000122967.3	Gprc5c Ensembl NCBI MGI UniProt Show fit	G protein-coupled receptor, family C, group 5, member C
chr19_+_42078859 Show fit	1.88	ENSMUST00000235932.2 ENSMUST00000066778.6	Pi4k2a Ensembl NCBI MGI UniProt Show fit	phosphatidylinositol 4-kinase type 2 alpha
chr4_-_104733580 Show fit	1.87	ENSMUST00000064873.9 ENSMUST00000106808.10 ENSMUST00000048947.15	C8a Ensembl NCBI MGI UniProt Show fit	complement component 8, alpha polypeptide
chr3_+_146302832 Show fit	1.87	ENSMUST00000029837.14 ENSMUST00000147409.2 ENSMUST00000121133.2	Uox Ensembl NCBI MGI UniProt Show fit	urate oxidase
chr7_+_112806672 Show fit	1.83	ENSMUST00000047321.9 ENSMUST00000210074.2 ENSMUST00000210238.2	Arntl Ensembl NCBI MGI UniProt Show fit	aryl hydrocarbon receptor nuclear translocator-like
chr5_-_87572060 Show fit	1.83	ENSMUST00000072818.6	Ugt2b38 Ensembl NCBI MGI UniProt Show fit	UDP glucuronosyltransferase 2 family, polypeptide B38
chr3_+_107137924 Show fit	1.82	ENSMUST00000179399.3	A630076J17Rik Ensembl NCBI MGI UniProt Show fit	RIKEN cDNA A630076J17 gene
chr4_+_104623505 Show fit	1.80	ENSMUST00000031663.10 ENSMUST00000065072.7	C8b Ensembl NCBI MGI UniProt Show fit	complement component 8, beta polypeptide
chr5_+_90608751 Show fit	1.79	ENSMUST00000031314.10	Alb Ensembl NCBI MGI UniProt Show fit	albumin
chr17_+_25097199 Show fit	1.79	ENSMUST00000050714.8	Igfals Ensembl NCBI MGI UniProt Show fit	insulin-like growth factor binding protein, acid labile subunit
chr4_+_34893772 Show fit	1.76	ENSMUST00000029975.10 ENSMUST00000135871.8 ENSMUST00000108130.2	Cga Ensembl NCBI MGI UniProt Show fit	glycoprotein hormones, alpha subunit
chr14_-_66246652 Show fit	1.69	ENSMUST00000059970.9	Gulo Ensembl NCBI MGI UniProt Show fit	gulonolactone (L-) oxidase
chr15_+_99290763 Show fit	1.69	ENSMUST00000023749.15	Tmbim6 Ensembl NCBI MGI UniProt Show fit	transmembrane BAX inhibitor motif containing 6
chr19_+_23118545 Show fit	1.69	ENSMUST00000036884.3	Klf9 Ensembl NCBI MGI UniProt Show fit	Kruppel-like factor 9
chr10_-_95678786 Show fit	1.66	ENSMUST00000211096.2	Gm33543 Ensembl NCBI MGI UniProt Show fit	predicted gene, 33543
chr19_-_34856853 Show fit	1.65	ENSMUST00000036584.13	Pank1 Ensembl NCBI MGI UniProt Show fit	pantothenate kinase 1
chr14_-_31362909 Show fit	1.64	ENSMUST00000022437.16	Hacl1 Ensembl NCBI MGI UniProt Show fit	2-hydroxyacyl-CoA lyase 1
chr9_-_45866468 Show fit	1.62	ENSMUST00000162072.8	Sidt2 Ensembl NCBI MGI UniProt Show fit	SID1 transmembrane family, member 2
chr18_-_60881679 Show fit	1.61	ENSMUST00000237783.2	Ndst1 Ensembl NCBI MGI UniProt Show fit	N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1
chr4_-_19922599 Show fit	1.60	ENSMUST00000029900.6	Atp6v0d2 Ensembl NCBI MGI UniProt Show fit	ATPase, H+ transporting, lysosomal V0 subunit D2
chr9_-_45866264 Show fit	1.59	ENSMUST00000114573.9	Sidt2 Ensembl NCBI MGI UniProt Show fit	SID1 transmembrane family, member 2
chr1_+_52158693 Show fit	1.59	ENSMUST00000189347.7	Stat1 Ensembl NCBI MGI UniProt Show fit	signal transducer and activator of transcription 1
chr1_-_179373826 Show fit	1.55	ENSMUST00000027769.6	Tfb2m Ensembl NCBI MGI UniProt Show fit	transcription factor B2, mitochondrial
chr10_+_87696339 Show fit	1.51	ENSMUST00000121161.8	Igf1 Ensembl NCBI MGI UniProt Show fit	insulin-like growth factor 1
chr11_+_118913788 Show fit	1.50	ENSMUST00000026662.8	Cbx2 Ensembl NCBI MGI UniProt Show fit	chromobox 2
chr15_+_59520199 Show fit	1.50	ENSMUST00000067543.8	Trib1 Ensembl NCBI MGI UniProt Show fit	tribbles pseudokinase 1
chr1_+_52158599 Show fit	1.50	ENSMUST00000186574.7 ENSMUST00000070968.14 ENSMUST00000191435.7 ENSMUST00000186857.7 ENSMUST00000188681.7	Stat1 Ensembl NCBI MGI UniProt Show fit	signal transducer and activator of transcription 1
chr3_+_85946145 Show fit	1.49	ENSMUST00000238331.2	Sh3d19 Ensembl NCBI MGI UniProt Show fit	SH3 domain protein D19
chr7_-_80052491 Show fit	1.49	ENSMUST00000122232.8	Furin Ensembl NCBI MGI UniProt Show fit	furin (paired basic amino acid cleaving enzyme)
chr9_-_44714263 Show fit	1.48	ENSMUST00000044694.8	Ttc36 Ensembl NCBI MGI UniProt Show fit	tetratricopeptide repeat domain 36
chr3_+_52175757 Show fit	1.47	ENSMUST00000053764.7	Foxo1 Ensembl NCBI MGI UniProt Show fit	forkhead box O1
chr19_-_58443830 Show fit	1.47	ENSMUST00000026076.14	Gfra1 Ensembl NCBI MGI UniProt Show fit	glial cell line derived neurotrophic factor family receptor alpha 1
chr9_+_47441471 Show fit	1.45	ENSMUST00000114548.8 ENSMUST00000152459.8 ENSMUST00000143026.9 ENSMUST00000085909.9 ENSMUST00000114547.8 ENSMUST00000239368.2 ENSMUST00000214542.2 ENSMUST00000034581.4	Cadm1 Ensembl NCBI MGI UniProt Show fit	cell adhesion molecule 1
chr10_-_18110682 Show fit	1.44	ENSMUST00000052648.9 ENSMUST00000080860.13 ENSMUST00000173243.8	Ccdc28a Ensembl NCBI MGI UniProt Show fit	coiled-coil domain containing 28A
chr12_-_83643883 Show fit	1.44	ENSMUST00000221919.2	Zfyve1 Ensembl NCBI MGI UniProt Show fit	zinc finger, FYVE domain containing 1
chr7_+_100966289 Show fit	1.44	ENSMUST00000163799.9 ENSMUST00000164479.9	Stard10 Ensembl NCBI MGI UniProt Show fit	START domain containing 10
chr19_-_58443593 Show fit	1.44	ENSMUST00000135730.2 ENSMUST00000152507.8	Gfra1 Ensembl NCBI MGI UniProt Show fit	glial cell line derived neurotrophic factor family receptor alpha 1
chr17_-_34846323 Show fit	1.43	ENSMUST00000168709.3 ENSMUST00000064953.15 ENSMUST00000170345.8 ENSMUST00000171121.9 ENSMUST00000168391.9 ENSMUST00000169067.9	Gm20460 Ensembl NCBI MGI UniProt Show fit Ppt2 Ensembl NCBI MGI UniProt Show fit	predicted gene 20460 palmitoyl-protein thioesterase 2
chr1_+_67162176 Show fit	1.43	ENSMUST00000027144.8	Cps1 Ensembl NCBI MGI UniProt Show fit	carbamoyl-phosphate synthetase 1
chr10_+_127734384 Show fit	1.41	ENSMUST00000047134.8	Sdr9c7 Ensembl NCBI MGI UniProt Show fit	4short chain dehydrogenase/reductase family 9C, member 7
chr12_-_83643964 Show fit	1.41	ENSMUST00000048319.6	Zfyve1 Ensembl NCBI MGI UniProt Show fit	zinc finger, FYVE domain containing 1
chr6_+_134807097 Show fit	1.41	ENSMUST00000046303.12	Crebl2 Ensembl NCBI MGI UniProt Show fit	cAMP responsive element binding protein-like 2
chr1_+_9618173 Show fit	1.39	ENSMUST00000144177.8	Adhfe1 Ensembl NCBI MGI UniProt Show fit	alcohol dehydrogenase, iron containing, 1
chr11_-_84058292 Show fit	1.39	ENSMUST00000050771.8	Gm11437 Ensembl NCBI MGI UniProt Show fit	predicted gene 11437
chr1_+_52158721 Show fit	1.39	ENSMUST00000186057.7	Stat1 Ensembl NCBI MGI UniProt Show fit	signal transducer and activator of transcription 1
chr1_+_106099482 Show fit	1.38	ENSMUST00000061047.7	Phlpp1 Ensembl NCBI MGI UniProt Show fit	PH domain and leucine rich repeat protein phosphatase 1
chr3_+_20011251 Show fit	1.38	ENSMUST00000108328.8	Cp Ensembl NCBI MGI UniProt Show fit	ceruloplasmin
chr3_+_20011201 Show fit	1.36	ENSMUST00000091309.12 ENSMUST00000108329.8 ENSMUST00000003714.13	Cp Ensembl NCBI MGI UniProt Show fit	ceruloplasmin
chr10_-_95678748 Show fit	1.34	ENSMUST00000210336.2	Gm33543 Ensembl NCBI MGI UniProt Show fit	predicted gene, 33543
chr5_-_147259245 Show fit	1.34	ENSMUST00000100433.5	Urad Ensembl NCBI MGI UniProt Show fit	ureidoimidazoline (2-oxo-4-hydroxy-4-carboxy-5) decarboxylase
chr3_+_90161470 Show fit	1.31	ENSMUST00000029545.15	Crtc2 Ensembl NCBI MGI UniProt Show fit	CREB regulated transcription coactivator 2
chr6_-_52617288 Show fit	1.30	ENSMUST00000031788.9	Hibadh Ensembl NCBI MGI UniProt Show fit	3-hydroxyisobutyrate dehydrogenase
chr19_+_29078765 Show fit	1.29	ENSMUST00000064393.6 ENSMUST00000235900.2	Rcl1 Ensembl NCBI MGI UniProt Show fit	RNA terminal phosphate cyclase-like 1
chr2_+_4722956 Show fit	1.29	ENSMUST00000056914.7	Bend7 Ensembl NCBI MGI UniProt Show fit	BEN domain containing 7
chr11_-_100288566 Show fit	1.26	ENSMUST00000001592.15 ENSMUST00000107403.2	Jup Ensembl NCBI MGI UniProt Show fit	junction plakoglobin
chr15_-_96947963 Show fit	1.25	ENSMUST00000230907.2	Slc38a4 Ensembl NCBI MGI UniProt Show fit	solute carrier family 38, member 4
chr1_+_75119472 Show fit	1.25	ENSMUST00000189650.7	Retreg2 Ensembl NCBI MGI UniProt Show fit	reticulophagy regulator family member 2
chr9_+_110162470 Show fit	1.24	ENSMUST00000198761.5 ENSMUST00000197630.3	Scap Ensembl NCBI MGI UniProt Show fit	SREBF chaperone
chr7_+_127400016 Show fit	1.24	ENSMUST00000106271.2 ENSMUST00000138432.2	Hsd3b7 Ensembl NCBI MGI UniProt Show fit	hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7
chr1_+_75119419 Show fit	1.24	ENSMUST00000097694.11 ENSMUST00000190240.7	Retreg2 Ensembl NCBI MGI UniProt Show fit	reticulophagy regulator family member 2
chr2_-_64806106 Show fit	1.23	ENSMUST00000156765.2	Grb14 Ensembl NCBI MGI UniProt Show fit	growth factor receptor bound protein 14
chr15_-_39720855 Show fit	1.23	ENSMUST00000022915.11 ENSMUST00000110306.9	Dpys Ensembl NCBI MGI UniProt Show fit	dihydropyrimidinase
chr6_-_136852792 Show fit	1.23	ENSMUST00000032342.3	Mgp Ensembl NCBI MGI UniProt Show fit	matrix Gla protein
chr3_+_20011405 Show fit	1.23	ENSMUST00000108325.9	Cp Ensembl NCBI MGI UniProt Show fit	ceruloplasmin
chr4_-_49549489 Show fit	1.21	ENSMUST00000029987.10	Aldob Ensembl NCBI MGI UniProt Show fit	aldolase B, fructose-bisphosphate
chr9_+_46139878 Show fit	1.18	ENSMUST00000034588.9 ENSMUST00000132155.2	Apoa1 Ensembl NCBI MGI UniProt Show fit	apolipoprotein A-I
chr5_+_102629240 Show fit	1.16	ENSMUST00000073302.12 ENSMUST00000094559.9	Arhgap24 Ensembl NCBI MGI UniProt Show fit	Rho GTPase activating protein 24
chr10_+_96452860 Show fit	1.16	ENSMUST00000038377.9	Btg1 Ensembl NCBI MGI UniProt Show fit	BTG anti-proliferation factor 1
chr3_+_94269745 Show fit	1.14	ENSMUST00000169433.3	C2cd4d Ensembl NCBI MGI UniProt Show fit	C2 calcium-dependent domain containing 4D
chr9_-_103107495 Show fit	1.14	ENSMUST00000035158.16	Trf Ensembl NCBI MGI UniProt Show fit	transferrin
chr16_+_22710785 Show fit	1.13	ENSMUST00000023583.7 ENSMUST00000232098.2	Ahsg Ensembl NCBI MGI UniProt Show fit	alpha-2-HS-glycoprotein
chr17_+_37253802 Show fit	1.13	ENSMUST00000040498.12	Rnf39 Ensembl NCBI MGI UniProt Show fit	ring finger protein 39
chr17_+_34250757 Show fit	1.12	ENSMUST00000044858.16 ENSMUST00000174299.9	Rxrb Ensembl NCBI MGI UniProt Show fit	retinoid X receptor beta
chr17_+_25059079 Show fit	1.11	ENSMUST00000164251.8	Hagh Ensembl NCBI MGI UniProt Show fit	hydroxyacyl glutathione hydrolase
chr19_+_5927821 Show fit	1.11	ENSMUST00000145200.8 ENSMUST00000025732.14 ENSMUST00000125114.8 ENSMUST00000155697.8	Slc25a45 Ensembl NCBI MGI UniProt Show fit	solute carrier family 25, member 45
chrX_-_139443926 Show fit	1.11	ENSMUST00000055738.12	Tsc22d3 Ensembl NCBI MGI UniProt Show fit	TSC22 domain family, member 3
chr17_-_34846122 Show fit	1.11	ENSMUST00000171376.8 ENSMUST00000169287.2	Ppt2 Ensembl NCBI MGI UniProt Show fit	palmitoyl-protein thioesterase 2
chr9_-_103107460 Show fit	1.10	ENSMUST00000165296.8 ENSMUST00000112645.8	Trf Ensembl NCBI MGI UniProt Show fit	transferrin
chr19_+_4905158 Show fit	1.09	ENSMUST00000119694.3 ENSMUST00000237504.2 ENSMUST00000237011.2	Ctsf Ensembl NCBI MGI UniProt Show fit	cathepsin F
chr19_-_46661321 Show fit	1.09	ENSMUST00000026012.8	Cyp17a1 Ensembl NCBI MGI UniProt Show fit	cytochrome P450, family 17, subfamily a, polypeptide 1
chr2_+_173579285 Show fit	1.09	ENSMUST00000067530.6	Vapb Ensembl NCBI MGI UniProt Show fit	vesicle-associated membrane protein, associated protein B and C
chr9_+_53212871 Show fit	1.07	ENSMUST00000051014.2	Exph5 Ensembl NCBI MGI UniProt Show fit	exophilin 5
chr6_-_83633064 Show fit	1.07	ENSMUST00000014686.3	Clec4f Ensembl NCBI MGI UniProt Show fit	C-type lectin domain family 4, member f
chr15_-_96918203 Show fit	1.06	ENSMUST00000166223.2	Slc38a4 Ensembl NCBI MGI UniProt Show fit	solute carrier family 38, member 4
chr10_+_87695886 Show fit	1.05	ENSMUST00000062862.13	Igf1 Ensembl NCBI MGI UniProt Show fit	insulin-like growth factor 1
chr11_+_97576619 Show fit	1.05	ENSMUST00000107584.8 ENSMUST00000107585.9	Cisd3 Ensembl NCBI MGI UniProt Show fit	CDGSH iron sulfur domain 3
chr7_+_44499005 Show fit	1.05	ENSMUST00000150335.2 ENSMUST00000107882.8	Akt1s1 Ensembl NCBI MGI UniProt Show fit	AKT1 substrate 1 (proline-rich)
chr19_-_46661501 Show fit	1.05	ENSMUST00000236174.2	Cyp17a1 Ensembl NCBI MGI UniProt Show fit	cytochrome P450, family 17, subfamily a, polypeptide 1
chr19_-_34855278 Show fit	1.03	ENSMUST00000112460.3	Pank1 Ensembl NCBI MGI UniProt Show fit	pantothenate kinase 1
chr15_-_5137975 Show fit	1.03	ENSMUST00000118365.3	Card6 Ensembl NCBI MGI UniProt Show fit	caspase recruitment domain family, member 6
chr2_+_28531239 Show fit	1.03	ENSMUST00000028155.12 ENSMUST00000113869.8 ENSMUST00000113867.9	Tsc1 Ensembl NCBI MGI UniProt Show fit	TSC complex subunit 1
chr7_-_133384449 Show fit	1.03	ENSMUST00000063669.8	Dhx32 Ensembl NCBI MGI UniProt Show fit	DEAH (Asp-Glu-Ala-His) box polypeptide 32
chr1_-_184543367 Show fit	1.03	ENSMUST00000048462.13 ENSMUST00000110992.9	Mtarc1 Ensembl NCBI MGI UniProt Show fit	mitochondrial amidoxime reducing component 1
chr8_-_64659004 Show fit	1.02	ENSMUST00000066166.6	Tll1 Ensembl NCBI MGI UniProt Show fit	tolloid-like
chr17_+_34251041 Show fit	1.01	ENSMUST00000173354.9	Rxrb Ensembl NCBI MGI UniProt Show fit	retinoid X receptor beta
chr11_-_53313950 Show fit	1.01	ENSMUST00000036045.6	Leap2 Ensembl NCBI MGI UniProt Show fit	liver-expressed antimicrobial peptide 2
chr1_-_162726053 Show fit	1.00	ENSMUST00000143123.3	Fmo2 Ensembl NCBI MGI UniProt Show fit	flavin containing monooxygenase 2
chr15_+_59520493 Show fit	1.00	ENSMUST00000118228.2	Trib1 Ensembl NCBI MGI UniProt Show fit	tribbles pseudokinase 1
chr12_-_84447702 Show fit	0.99	ENSMUST00000122194.8	Entpd5 Ensembl NCBI MGI UniProt Show fit	ectonucleoside triphosphate diphosphohydrolase 5
chr8_-_85500010 Show fit	0.99	ENSMUST00000109764.8	Nfix Ensembl NCBI MGI UniProt Show fit	nuclear factor I/X
chr2_-_91025492 Show fit	0.98	ENSMUST00000111354.2	Nr1h3 Ensembl NCBI MGI UniProt Show fit	nuclear receptor subfamily 1, group H, member 3
chr18_-_32271224 Show fit	0.97	ENSMUST00000234657.2 ENSMUST00000234386.2 ENSMUST00000234651.2	Proc Ensembl NCBI MGI UniProt Show fit	protein C
chrX_+_100420873 Show fit	0.97	ENSMUST00000052130.14	Gjb1 Ensembl NCBI MGI UniProt Show fit	gap junction protein, beta 1
chr14_+_33662976 Show fit	0.97	ENSMUST00000100720.2	Gdf2 Ensembl NCBI MGI UniProt Show fit	growth differentiation factor 2
chr18_+_36797113 Show fit	0.96	ENSMUST00000036765.8	Eif4ebp3 Ensembl NCBI MGI UniProt Show fit	eukaryotic translation initiation factor 4E binding protein 3
chr2_+_67948057 Show fit	0.96	ENSMUST00000112346.3	B3galt1 Ensembl NCBI MGI UniProt Show fit	UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1
chr17_-_31363245 Show fit	0.94	ENSMUST00000024826.8	Tff2 Ensembl NCBI MGI UniProt Show fit	trefoil factor 2 (spasmolytic protein 1)
chr19_+_34268071 Show fit	0.94	ENSMUST00000112472.4 ENSMUST00000235232.2	Fas Ensembl NCBI MGI UniProt Show fit	Fas (TNF receptor superfamily member 6)
chr1_+_131898325 Show fit	0.93	ENSMUST00000027695.8	Slc45a3 Ensembl NCBI MGI UniProt Show fit	solute carrier family 45, member 3
chr19_+_31846154 Show fit	0.93	ENSMUST00000224564.2 ENSMUST00000224304.2 ENSMUST00000075838.8 ENSMUST00000224400.2	A1cf Ensembl NCBI MGI UniProt Show fit	APOBEC1 complementation factor
chr5_-_45607463 Show fit	0.91	ENSMUST00000197946.5 ENSMUST00000127562.3	Qdpr Ensembl NCBI MGI UniProt Show fit	quinoid dihydropteridine reductase
chr19_+_5927876 Show fit	0.91	ENSMUST00000235340.2	Slc25a45 Ensembl NCBI MGI UniProt Show fit	solute carrier family 25, member 45
chr6_-_124888643 Show fit	0.91	ENSMUST00000032217.2	Lag3 Ensembl NCBI MGI UniProt Show fit	lymphocyte-activation gene 3
chr6_+_79794899 Show fit	0.91	ENSMUST00000179797.3	Gm20594 Ensembl NCBI MGI UniProt Show fit	predicted gene, 20594
chr12_-_84447625 Show fit	0.90	ENSMUST00000117286.2	Entpd5 Ensembl NCBI MGI UniProt Show fit	ectonucleoside triphosphate diphosphohydrolase 5
chr6_+_87405968 Show fit	0.90	ENSMUST00000032125.7	Bmp10 Ensembl NCBI MGI UniProt Show fit	bone morphogenetic protein 10
chr19_-_34855242 Show fit	0.90	ENSMUST00000238065.2	Pank1 Ensembl NCBI MGI UniProt Show fit	pantothenate kinase 1
chrX_+_7588453 Show fit	0.90	ENSMUST00000043045.10 ENSMUST00000207386.2 ENSMUST00000116634.9 ENSMUST00000208072.2 ENSMUST00000207589.2 ENSMUST00000208618.2 ENSMUST00000208443.2 ENSMUST00000207541.2 ENSMUST00000208528.2 ENSMUST00000115689.10 ENSMUST00000131077.9 ENSMUST00000115688.8 ENSMUST00000208156.2	Wdr45 Ensembl NCBI MGI UniProt Show fit Gm45208 Ensembl NCBI MGI UniProt Show fit	WD repeat domain 45 predicted gene 45208
chr3_+_122277372 Show fit	0.90	ENSMUST00000197073.2	Bcar3 Ensembl NCBI MGI UniProt Show fit	breast cancer anti-estrogen resistance 3
chr10_+_116111441 Show fit	0.89	ENSMUST00000218553.2	Ptprb Ensembl NCBI MGI UniProt Show fit	protein tyrosine phosphatase, receptor type, B
chr15_-_53209513 Show fit	0.89	ENSMUST00000077273.9	Ext1 Ensembl NCBI MGI UniProt Show fit	exostosin glycosyltransferase 1
chr7_-_25089522 Show fit	0.89	ENSMUST00000054301.14	Lipe Ensembl NCBI MGI UniProt Show fit	lipase, hormone sensitive
chrX_+_7588505 Show fit	0.88	ENSMUST00000207675.2 ENSMUST00000116633.9 ENSMUST00000208996.2 ENSMUST00000144148.4 ENSMUST00000125991.9 ENSMUST00000148624.8	Wdr45 Ensembl NCBI MGI UniProt Show fit	WD repeat domain 45
chr4_-_45012093 Show fit	0.87	ENSMUST00000131991.2	Zbtb5 Ensembl NCBI MGI UniProt Show fit	zinc finger and BTB domain containing 5
chr11_+_96920956 Show fit	0.87	ENSMUST00000153482.2	Scrn2 Ensembl NCBI MGI UniProt Show fit	secernin 2
chr12_-_103923145 Show fit	0.86	ENSMUST00000085054.5	Serpina1e Ensembl NCBI MGI UniProt Show fit	serine (or cysteine) peptidase inhibitor, clade A, member 1E
chr7_+_44498415 Show fit	0.86	ENSMUST00000107885.8	Akt1s1 Ensembl NCBI MGI UniProt Show fit	AKT1 substrate 1 (proline-rich)
chr13_+_58305455 Show fit	0.86	ENSMUST00000226010.2 ENSMUST00000051490.15 ENSMUST00000109868.4	Idnk Ensembl NCBI MGI UniProt Show fit	idnK gluconokinase homolog (E. coli)
chr13_-_53083494 Show fit	0.86	ENSMUST00000123599.8	Auh Ensembl NCBI MGI UniProt Show fit	AU RNA binding protein/enoyl-coenzyme A hydratase
chr2_+_24866039 Show fit	0.85	ENSMUST00000045295.14	Pnpla7 Ensembl NCBI MGI UniProt Show fit	patatin-like phospholipase domain containing 7
chr19_+_46611826 Show fit	0.85	ENSMUST00000111855.5	Wbp1l Ensembl NCBI MGI UniProt Show fit	WW domain binding protein 1 like
chr15_-_96929086 Show fit	0.85	ENSMUST00000230086.2	Slc38a4 Ensembl NCBI MGI UniProt Show fit	solute carrier family 38, member 4
chr5_+_28370687 Show fit	0.85	ENSMUST00000036177.9	En2 Ensembl NCBI MGI UniProt Show fit	engrailed 2
chr9_+_44951075 Show fit	0.85	ENSMUST00000217097.2	Mpzl2 Ensembl NCBI MGI UniProt Show fit	myelin protein zero-like 2
chr3_-_146302343 Show fit	0.85	ENSMUST00000029836.9	Dnase2b Ensembl NCBI MGI UniProt Show fit	deoxyribonuclease II beta
chr11_+_114742619 Show fit	0.84	ENSMUST00000053361.12 ENSMUST00000021071.14 ENSMUST00000136785.2	Gprc5c Ensembl NCBI MGI UniProt Show fit	G protein-coupled receptor, family C, group 5, member C
chr11_-_52173391 Show fit	0.84	ENSMUST00000086844.10	Tcf7 Ensembl NCBI MGI UniProt Show fit	transcription factor 7, T cell specific
chr19_-_58444336 Show fit	0.83	ENSMUST00000131877.2	Gfra1 Ensembl NCBI MGI UniProt Show fit	glial cell line derived neurotrophic factor family receptor alpha 1
chrX_+_93278203 Show fit	0.83	ENSMUST00000153900.8	Klhl15 Ensembl NCBI MGI UniProt Show fit	kelch-like 15
chr5_-_87402659 Show fit	0.83	ENSMUST00000075858.4	Ugt2b37 Ensembl NCBI MGI UniProt Show fit	UDP glucuronosyltransferase 2 family, polypeptide B37
chr13_-_53083674 Show fit	0.82	ENSMUST00000120535.8 ENSMUST00000119311.8 ENSMUST00000021913.16 ENSMUST00000110031.4	Auh Ensembl NCBI MGI UniProt Show fit	AU RNA binding protein/enoyl-coenzyme A hydratase

Network of associatons between targets according to the STRING database.

First level regulatory network of Foxp2_Foxp3

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
2.1	12.8	GO:0090360	platelet-derived growth factor production(GO:0090360) regulation of platelet-derived growth factor production(GO:0090361)
1.7	6.6	GO:0010901	regulation of very-low-density lipoprotein particle remodeling(GO:0010901)
1.5	4.5	GO:0034240	negative regulation of macrophage fusion(GO:0034240)
1.4	7.1	GO:1904721	regulation of mRNA cleavage(GO:0031437) negative regulation of mRNA cleavage(GO:0031438) regulation of mRNA endonucleolytic cleavage involved in unfolded protein response(GO:1904720) negative regulation of mRNA endonucleolytic cleavage involved in unfolded protein response(GO:1904721)
1.1	1.1	GO:0046725	negative regulation by virus of viral protein levels in host cell(GO:0046725)
1.1	7.5	GO:0001561	fatty acid alpha-oxidation(GO:0001561)
1.0	4.9	GO:0009992	cellular water homeostasis(GO:0009992)
0.8	2.5	GO:0045645	regulation of eosinophil differentiation(GO:0045643) positive regulation of eosinophil differentiation(GO:0045645)
0.8	3.3	GO:0019859	pyrimidine nucleobase catabolic process(GO:0006208) thymine catabolic process(GO:0006210) thymine metabolic process(GO:0019859)
0.8	4.0	GO:0006548	histidine catabolic process(GO:0006548)
0.8	2.3	GO:0019740	regulation of nitrogen utilization(GO:0006808) nitrogen utilization(GO:0019740)
0.7	4.9	GO:1904075	regulation of trophectodermal cell proliferation(GO:1904073) positive regulation of trophectodermal cell proliferation(GO:1904075)
0.6	1.9	GO:0002276	basophil activation involved in immune response(GO:0002276)
0.6	1.8	GO:0051659	maintenance of mitochondrion location(GO:0051659)
0.6	3.6	GO:0010248	establishment or maintenance of transmembrane electrochemical gradient(GO:0010248)
0.6	3.4	GO:0072592	oxygen metabolic process(GO:0072592)
0.5	1.6	GO:0006391	transcription initiation from mitochondrial promoter(GO:0006391)
0.5	2.0	GO:0045329	carnitine biosynthetic process(GO:0045329)
0.4	1.2	GO:1903538	meiotic cell cycle process involved in oocyte maturation(GO:1903537) regulation of meiotic cell cycle process involved in oocyte maturation(GO:1903538)
0.4	4.1	GO:0016338	calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.4	9.3	GO:0048387	negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.4	2.7	GO:0000103	sulfate assimilation(GO:0000103)
0.4	0.8	GO:0060151	peroxisome localization(GO:0060151) microtubule-based peroxisome localization(GO:0060152)
0.4	1.5	GO:0090472	dibasic protein processing(GO:0090472)
0.4	1.8	GO:0090403	oxidative stress-induced premature senescence(GO:0090403)
0.4	2.5	GO:1901509	regulation of endothelial tube morphogenesis(GO:1901509)
0.3	8.3	GO:0006744	ubiquinone biosynthetic process(GO:0006744)
0.3	1.0	GO:0090650	rRNA export from nucleus(GO:0006407) response to oxygen-glucose deprivation(GO:0090649) cellular response to oxygen-glucose deprivation(GO:0090650)
0.3	1.7	GO:0019853	L-ascorbic acid biosynthetic process(GO:0019853)
0.3	1.0	GO:1990164	histone H3-S28 phosphorylation(GO:0043988) histone H2A phosphorylation(GO:1990164)
0.3	2.7	GO:0007597	blood coagulation, intrinsic pathway(GO:0007597)
0.3	2.6	GO:0001887	selenium compound metabolic process(GO:0001887)
0.3	3.6	GO:0015868	purine ribonucleotide transport(GO:0015868)
0.3	0.9	GO:0031104	dendrite regeneration(GO:0031104)
0.3	0.9	GO:0046340	diacylglycerol catabolic process(GO:0046340)
0.3	3.2	GO:0033227	dsRNA transport(GO:0033227)
0.3	2.3	GO:0070447	positive regulation of oligodendrocyte progenitor proliferation(GO:0070447)
0.3	0.8	GO:0002386	immune response in mucosal-associated lymphoid tissue(GO:0002386)
0.3	0.8	GO:0006553	lysine metabolic process(GO:0006553)
0.3	1.3	GO:0000480	endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000480)
0.3	0.8	GO:1902524	positive regulation of protein K48-linked ubiquitination(GO:1902524)
0.3	1.5	GO:0002159	desmosome assembly(GO:0002159)
0.2	3.0	GO:0097421	liver regeneration(GO:0097421)
0.2	1.0	GO:0090341	negative regulation of secretion of lysosomal enzymes(GO:0090341)
0.2	1.7	GO:0050847	progesterone receptor signaling pathway(GO:0050847)
0.2	0.5	GO:0060741	prostate gland stromal morphogenesis(GO:0060741)
0.2	0.9	GO:0015772	disaccharide transport(GO:0015766) sucrose transport(GO:0015770) oligosaccharide transport(GO:0015772)
0.2	0.9	GO:0010609	mRNA localization resulting in posttranscriptional regulation of gene expression(GO:0010609)
0.2	0.2	GO:0002777	antimicrobial peptide biosynthetic process(GO:0002777) antibacterial peptide biosynthetic process(GO:0002780)
0.2	3.7	GO:0006957	complement activation, alternative pathway(GO:0006957)
0.2	3.9	GO:0051873	disruption by host of symbiont cells(GO:0051852) killing by host of symbiont cells(GO:0051873)
0.2	0.4	GO:2000978	negative regulation of forebrain neuron differentiation(GO:2000978)
0.2	0.6	GO:0045013	carbon catabolite repression of transcription(GO:0045013) negative regulation of transcription by glucose(GO:0045014)
0.2	1.4	GO:0006207	'de novo' pyrimidine nucleobase biosynthetic process(GO:0006207) pyrimidine nucleobase biosynthetic process(GO:0019856)
0.2	0.6	GO:0001982	baroreceptor response to decreased systemic arterial blood pressure(GO:0001982)
0.2	1.2	GO:0006116	NADH oxidation(GO:0006116)
0.2	0.8	GO:0090187	positive regulation of pancreatic juice secretion(GO:0090187)
0.2	1.8	GO:0015014	heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.2	0.6	GO:0090673	endothelial cell-matrix adhesion(GO:0090673)
0.2	0.6	GO:0015783	GDP-fucose transport(GO:0015783) purine nucleotide-sugar transport(GO:0036079)
0.2	0.6	GO:0001966	thigmotaxis(GO:0001966)
0.2	3.6	GO:0034033	coenzyme A biosynthetic process(GO:0015937) nucleoside bisphosphate biosynthetic process(GO:0033866) ribonucleoside bisphosphate biosynthetic process(GO:0034030) purine nucleoside bisphosphate biosynthetic process(GO:0034033)
0.2	0.8	GO:0006069	ethanol oxidation(GO:0006069)
0.2	3.7	GO:0097264	self proteolysis(GO:0097264)
0.2	5.7	GO:0015721	bile acid and bile salt transport(GO:0015721)
0.2	0.6	GO:0090327	negative regulation of locomotion involved in locomotory behavior(GO:0090327)
0.2	4.8	GO:0017144	drug metabolic process(GO:0017144)
0.2	0.5	GO:0060584	regulation of prostaglandin-endoperoxide synthase activity(GO:0060584) positive regulation of prostaglandin-endoperoxide synthase activity(GO:0060585)
0.2	1.4	GO:0090038	negative regulation of protein kinase C signaling(GO:0090038)
0.2	0.5	GO:0021529	spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530)
0.2	1.5	GO:0061709	reticulophagy(GO:0061709)
0.2	1.1	GO:0032497	detection of lipopolysaccharide(GO:0032497)
0.2	0.5	GO:0030070	insulin processing(GO:0030070)
0.2	0.6	GO:0009257	histidine biosynthetic process(GO:0000105) 10-formyltetrahydrofolate biosynthetic process(GO:0009257)
0.2	0.8	GO:0070859	positive regulation of bile acid biosynthetic process(GO:0070859) positive regulation of bile acid metabolic process(GO:1904253)
0.2	0.9	GO:0060455	negative regulation of gastric acid secretion(GO:0060455)
0.2	3.0	GO:0009083	branched-chain amino acid catabolic process(GO:0009083)
0.2	1.6	GO:0035021	negative regulation of Rac protein signal transduction(GO:0035021)
0.2	1.1	GO:0071985	multivesicular body sorting pathway(GO:0071985)
0.2	0.6	GO:0000239	pachytene(GO:0000239) RNA 5'-end processing(GO:0000966)
0.1	0.4	GO:0033189	response to vitamin A(GO:0033189)
0.1	0.4	GO:0086097	phospholipase C-activating angiotensin-activated signaling pathway(GO:0086097)
0.1	3.0	GO:0006704	glucocorticoid biosynthetic process(GO:0006704)
0.1	1.0	GO:0006083	acetate metabolic process(GO:0006083)
0.1	0.7	GO:0048807	female genitalia morphogenesis(GO:0048807)
0.1	1.5	GO:0071455	cellular response to hyperoxia(GO:0071455)
0.1	0.9	GO:0071630	nucleus-associated proteasomal ubiquitin-dependent protein catabolic process(GO:0071630)
0.1	0.6	GO:0032074	negative regulation of nuclease activity(GO:0032074)
0.1	2.7	GO:0045792	negative regulation of cell size(GO:0045792)
0.1	3.2	GO:0006144	purine nucleobase metabolic process(GO:0006144)
0.1	1.7	GO:0046884	follicle-stimulating hormone secretion(GO:0046884)
0.1	0.7	GO:0038161	prolactin signaling pathway(GO:0038161)
0.1	0.2	GO:0002803	positive regulation of antimicrobial peptide production(GO:0002225) positive regulation of antibacterial peptide production(GO:0002803)
0.1	1.3	GO:0035754	B cell chemotaxis(GO:0035754)
0.1	2.3	GO:1990001	inhibition of cysteine-type endopeptidase activity involved in apoptotic process(GO:1990001)
0.1	3.1	GO:0045603	positive regulation of endothelial cell differentiation(GO:0045603)
0.1	0.7	GO:0099551	synaptic signaling via neuropeptide(GO:0099538) trans-synaptic signaling by neuropeptide(GO:0099540) trans-synaptic signaling by neuropeptide, modulating synaptic transmission(GO:0099551)
0.1	1.1	GO:0019243	methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione(GO:0019243) methylglyoxal catabolic process(GO:0051596) methylglyoxal catabolic process to lactate(GO:0061727)
0.1	0.4	GO:0032915	positive regulation of transforming growth factor beta2 production(GO:0032915)
0.1	1.2	GO:0008063	Toll signaling pathway(GO:0008063)
0.1	4.0	GO:0046688	response to copper ion(GO:0046688)
0.1	1.0	GO:0019375	galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.1	0.6	GO:0034638	phosphatidylcholine catabolic process(GO:0034638)
0.1	1.7	GO:0060501	positive regulation of epithelial cell proliferation involved in lung morphogenesis(GO:0060501)
0.1	1.1	GO:0070236	negative regulation of activation-induced cell death of T cells(GO:0070236)
0.1	1.7	GO:0034497	protein localization to pre-autophagosomal structure(GO:0034497)
0.1	0.8	GO:2000860	positive regulation of mineralocorticoid secretion(GO:2000857) positive regulation of aldosterone secretion(GO:2000860)
0.1	0.5	GO:2000124	endocannabinoid signaling pathway(GO:0071926) regulation of endocannabinoid signaling pathway(GO:2000124)
0.1	0.9	GO:0006729	tetrahydrobiopterin biosynthetic process(GO:0006729)
0.1	0.9	GO:0045085	negative regulation of interleukin-2 biosynthetic process(GO:0045085)
0.1	0.6	GO:0043415	positive regulation of skeletal muscle tissue regeneration(GO:0043415)
0.1	0.7	GO:1902732	positive regulation of chondrocyte proliferation(GO:1902732)
0.1	12.9	GO:0006958	complement activation, classical pathway(GO:0006958)
0.1	0.3	GO:1901165	positive regulation of trophoblast cell migration(GO:1901165)
0.1	0.8	GO:0002568	somatic diversification of T cell receptor genes(GO:0002568) somatic recombination of T cell receptor gene segments(GO:0002681) T cell receptor V(D)J recombination(GO:0033153)
0.1	0.3	GO:2000657	regulation of apolipoprotein binding(GO:2000656) negative regulation of apolipoprotein binding(GO:2000657)
0.1	1.3	GO:0043970	histone H3-K9 acetylation(GO:0043970)
0.1	0.8	GO:0060836	lymphatic endothelial cell differentiation(GO:0060836)
0.1	0.4	GO:0010157	response to chlorate(GO:0010157)
0.1	2.4	GO:0007035	vacuolar acidification(GO:0007035)
0.1	0.2	GO:1990926	short-term synaptic potentiation(GO:1990926)
0.1	0.2	GO:1903027	regulation of opsonization(GO:1903027) positive regulation of opsonization(GO:1903028)
0.1	0.8	GO:0060613	fat pad development(GO:0060613)
0.1	0.4	GO:0007468	regulation of rhodopsin gene expression(GO:0007468) positive regulation of rhodopsin gene expression(GO:0045872)
0.1	0.4	GO:0007084	mitotic nuclear envelope reassembly(GO:0007084)
0.1	0.3	GO:0072233	ascending thin limb development(GO:0072021) thick ascending limb development(GO:0072023) metanephric ascending thin limb development(GO:0072218) metanephric thick ascending limb development(GO:0072233)
0.1	0.5	GO:0006499	N-terminal protein myristoylation(GO:0006499)
0.1	10.8	GO:0055088	lipid homeostasis(GO:0055088)
0.1	0.8	GO:0090166	Golgi disassembly(GO:0090166)
0.1	0.2	GO:0097273	creatinine homeostasis(GO:0097273) cellular ammonia homeostasis(GO:0097275) cellular creatinine homeostasis(GO:0097276) cellular urea homeostasis(GO:0097277)
0.1	0.3	GO:2000312	regulation of kainate selective glutamate receptor activity(GO:2000312)
0.1	1.7	GO:0051044	positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.1	3.0	GO:0055012	ventricular cardiac muscle cell differentiation(GO:0055012)
0.1	0.3	GO:2001205	negative regulation of osteoclast development(GO:2001205)
0.1	1.0	GO:0043589	skin morphogenesis(GO:0043589)
0.1	1.3	GO:0045947	negative regulation of translational initiation(GO:0045947)
0.1	0.6	GO:0019532	oxalate transport(GO:0019532)
0.1	0.3	GO:0050812	regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510) regulation of acyl-CoA biosynthetic process(GO:0050812)
0.1	0.4	GO:0048496	maintenance of organ identity(GO:0048496)
0.1	0.3	GO:0072733	response to staurosporine(GO:0072733) cellular response to staurosporine(GO:0072734)
0.1	0.3	GO:0001920	negative regulation of receptor recycling(GO:0001920)
0.1	0.5	GO:0060762	germ-line stem cell division(GO:0042078) male germ-line stem cell asymmetric division(GO:0048133) regulation of branching involved in mammary gland duct morphogenesis(GO:0060762) germline stem cell asymmetric division(GO:0098728)
0.1	1.0	GO:0048752	semicircular canal morphogenesis(GO:0048752)
0.1	0.3	GO:0006432	phenylalanyl-tRNA aminoacylation(GO:0006432)
0.1	1.1	GO:0051132	NK T cell activation(GO:0051132)
0.1	0.2	GO:2001015	negative regulation of skeletal muscle cell differentiation(GO:2001015)
0.1	0.3	GO:0070495	regulation of thrombin receptor signaling pathway(GO:0070494) negative regulation of thrombin receptor signaling pathway(GO:0070495)
0.1	0.3	GO:0070602	regulation of centromeric sister chromatid cohesion(GO:0070602)
0.1	1.0	GO:0010745	negative regulation of macrophage derived foam cell differentiation(GO:0010745)
0.1	0.2	GO:2000973	regulation of pro-B cell differentiation(GO:2000973)
0.1	0.2	GO:0051182	coenzyme transport(GO:0051182)
0.1	0.3	GO:1901837	negative regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901837)
0.1	0.2	GO:0060800	regulation of cell differentiation involved in embryonic placenta development(GO:0060800)
0.1	0.7	GO:0033089	positive regulation of T cell differentiation in thymus(GO:0033089) positive regulation of thymocyte aggregation(GO:2000400)
0.1	0.8	GO:0031507	heterochromatin assembly(GO:0031507)
0.1	1.0	GO:0021707	cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.1	1.2	GO:0071501	response to sterol depletion(GO:0006991) SREBP signaling pathway(GO:0032933) cellular response to sterol depletion(GO:0071501)
0.1	0.6	GO:0033689	negative regulation of osteoblast proliferation(GO:0033689)
0.1	0.8	GO:1990403	embryonic brain development(GO:1990403)
0.1	0.5	GO:0001766	membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580)
0.1	0.5	GO:0043402	glucocorticoid mediated signaling pathway(GO:0043402)
0.1	0.6	GO:0003352	regulation of cilium movement(GO:0003352)
0.0	0.8	GO:0006309	apoptotic DNA fragmentation(GO:0006309)
0.0	0.3	GO:0048208	vesicle targeting, rough ER to cis-Golgi(GO:0048207) COPII vesicle coating(GO:0048208)
0.0	0.7	GO:0090336	positive regulation of brown fat cell differentiation(GO:0090336)
0.0	0.3	GO:2000301	negative regulation of synaptic vesicle exocytosis(GO:2000301)
0.0	0.1	GO:1901856	negative regulation of cellular respiration(GO:1901856)
0.0	0.3	GO:0072092	ureteric bud invasion(GO:0072092)
0.0	0.3	GO:0044341	sodium-dependent phosphate transport(GO:0044341)
0.0	0.1	GO:0060854	patterning of lymph vessels(GO:0060854)
0.0	0.6	GO:0061635	regulation of protein complex stability(GO:0061635)
0.0	0.6	GO:0090557	establishment of endothelial intestinal barrier(GO:0090557)
0.0	0.7	GO:0046415	urate metabolic process(GO:0046415)
0.0	1.1	GO:0030502	negative regulation of bone mineralization(GO:0030502)
0.0	0.2	GO:0061031	endodermal digestive tract morphogenesis(GO:0061031)
0.0	0.7	GO:0014850	response to muscle activity(GO:0014850)
0.0	0.1	GO:0046604	positive regulation of mitotic centrosome separation(GO:0046604)
0.0	2.0	GO:0045600	positive regulation of fat cell differentiation(GO:0045600)
0.0	0.4	GO:0015747	urate transport(GO:0015747)
0.0	0.3	GO:0070245	positive regulation of thymocyte apoptotic process(GO:0070245)
0.0	0.2	GO:0043152	induction of bacterial agglutination(GO:0043152)
0.0	2.6	GO:0006094	gluconeogenesis(GO:0006094)
0.0	0.5	GO:0019227	neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.0	0.3	GO:0006689	ganglioside catabolic process(GO:0006689) oligosaccharide catabolic process(GO:0009313)
0.0	0.1	GO:1901979	regulation of inward rectifier potassium channel activity(GO:1901979)
0.0	0.4	GO:1902715	positive regulation of interferon-gamma secretion(GO:1902715)
0.0	0.3	GO:0010792	DNA double-strand break processing involved in repair via single-strand annealing(GO:0010792)
0.0	0.3	GO:0002934	desmosome organization(GO:0002934)
0.0	0.2	GO:0043031	negative regulation of macrophage activation(GO:0043031)
0.0	0.7	GO:0007194	negative regulation of adenylate cyclase activity(GO:0007194)
0.0	0.4	GO:1901898	negative regulation of relaxation of cardiac muscle(GO:1901898)
0.0	4.5	GO:0015718	monocarboxylic acid transport(GO:0015718)
0.0	0.6	GO:0006817	phosphate ion transport(GO:0006817)
0.0	0.1	GO:0008627	intrinsic apoptotic signaling pathway in response to osmotic stress(GO:0008627)
0.0	0.3	GO:0031179	peptide modification(GO:0031179)
0.0	0.4	GO:0042136	neurotransmitter biosynthetic process(GO:0042136)
0.0	0.3	GO:0090073	positive regulation of protein homodimerization activity(GO:0090073)
0.0	0.2	GO:1904694	negative regulation of vascular smooth muscle contraction(GO:1904694)
0.0	2.5	GO:0032024	positive regulation of insulin secretion(GO:0032024)
0.0	0.3	GO:0035988	chondrocyte proliferation(GO:0035988)
0.0	0.5	GO:0002031	G-protein coupled receptor internalization(GO:0002031)
0.0	0.5	GO:0015697	quaternary ammonium group transport(GO:0015697)
0.0	0.5	GO:0006123	mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.0	0.3	GO:0046543	development of secondary female sexual characteristics(GO:0046543)
0.0	1.5	GO:0003333	amino acid transmembrane transport(GO:0003333)
0.0	0.3	GO:0032625	interleukin-21 production(GO:0032625) interleukin-21 secretion(GO:0072619)
0.0	0.1	GO:0048743	positive regulation of skeletal muscle fiber development(GO:0048743)
0.0	0.1	GO:0061055	myotome development(GO:0061055)
0.0	0.1	GO:0045039	protein import into mitochondrial inner membrane(GO:0045039)
0.0	0.1	GO:0061303	cornea development in camera-type eye(GO:0061303)
0.0	2.9	GO:0009166	nucleotide catabolic process(GO:0009166)
0.0	0.4	GO:0071447	cellular response to hydroperoxide(GO:0071447)
0.0	0.3	GO:0072189	ureter development(GO:0072189)
0.0	0.2	GO:0048227	plasma membrane to endosome transport(GO:0048227)
0.0	0.2	GO:0002727	natural killer cell cytokine production(GO:0002370) regulation of natural killer cell cytokine production(GO:0002727)
0.0	0.3	GO:0032525	somite rostral/caudal axis specification(GO:0032525)
0.0	0.3	GO:0006977	DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest(GO:0006977) signal transduction involved in mitotic G1 DNA damage checkpoint(GO:0072431) intracellular signal transduction involved in G1 DNA damage checkpoint(GO:1902400)
0.0	0.1	GO:0021759	globus pallidus development(GO:0021759)
0.0	0.3	GO:0043653	mitochondrial fragmentation involved in apoptotic process(GO:0043653)
0.0	0.2	GO:0035887	aortic smooth muscle cell differentiation(GO:0035887)
0.0	0.9	GO:0002089	lens morphogenesis in camera-type eye(GO:0002089)
0.0	0.2	GO:0036438	maintenance of lens transparency(GO:0036438)
0.0	0.0	GO:2000546	positive regulation of cell chemotaxis to fibroblast growth factor(GO:1904849) positive regulation of endothelial cell chemotaxis to fibroblast growth factor(GO:2000546)
0.0	4.4	GO:0031668	cellular response to extracellular stimulus(GO:0031668)
0.0	0.1	GO:0038128	ERBB2 signaling pathway(GO:0038128)
0.0	0.8	GO:0003301	physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.0	0.5	GO:0031954	positive regulation of protein autophosphorylation(GO:0031954)
0.0	0.2	GO:0060136	embryonic process involved in female pregnancy(GO:0060136)
0.0	0.1	GO:0036151	phosphatidylcholine acyl-chain remodeling(GO:0036151)
0.0	0.8	GO:0070207	protein homotrimerization(GO:0070207)
0.0	0.4	GO:0021520	spinal cord motor neuron cell fate specification(GO:0021520)
0.0	0.1	GO:0007621	negative regulation of female receptivity(GO:0007621)
0.0	1.0	GO:0001938	positive regulation of endothelial cell proliferation(GO:0001938)
0.0	0.2	GO:2000507	positive regulation of energy homeostasis(GO:2000507)
0.0	0.1	GO:1902310	positive regulation of peptidyl-serine dephosphorylation(GO:1902310)
0.0	0.6	GO:1905144	acetylcholine receptor signaling pathway(GO:0095500) signal transduction involved in cellular response to ammonium ion(GO:1903831) response to acetylcholine(GO:1905144) cellular response to acetylcholine(GO:1905145)
0.0	0.3	GO:1902236	negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway(GO:1902236)
0.0	0.2	GO:0010839	negative regulation of keratinocyte proliferation(GO:0010839)
0.0	0.2	GO:0030277	maintenance of gastrointestinal epithelium(GO:0030277)
0.0	0.5	GO:0070536	protein K63-linked deubiquitination(GO:0070536)
0.0	0.0	GO:0060244	negative regulation of cell proliferation involved in contact inhibition(GO:0060244)
0.0	0.1	GO:1903054	negative regulation of extracellular matrix organization(GO:1903054)
0.0	0.2	GO:0019800	peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.0	0.2	GO:0006883	cellular sodium ion homeostasis(GO:0006883)
0.0	0.1	GO:1905053	regulation of base-excision repair(GO:1905051) positive regulation of base-excision repair(GO:1905053)
0.0	0.3	GO:0033539	fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
0.0	0.1	GO:0051919	positive regulation of fibrinolysis(GO:0051919)
0.0	0.1	GO:0045945	positive regulation of transcription from RNA polymerase III promoter(GO:0045945)
0.0	2.4	GO:0007601	visual perception(GO:0007601)
0.0	0.1	GO:0044314	protein K27-linked ubiquitination(GO:0044314)
0.0	2.5	GO:0050731	positive regulation of peptidyl-tyrosine phosphorylation(GO:0050731)
0.0	0.2	GO:0061002	negative regulation of dendritic spine morphogenesis(GO:0061002)
0.0	0.2	GO:0042594	response to starvation(GO:0042594)
0.0	0.3	GO:0071108	protein K48-linked deubiquitination(GO:0071108)
0.0	0.8	GO:0071594	T cell differentiation in thymus(GO:0033077) thymocyte aggregation(GO:0071594)
0.0	0.2	GO:0000188	inactivation of MAPK activity(GO:0000188)
0.0	0.7	GO:0006940	regulation of smooth muscle contraction(GO:0006940)
0.0	0.0	GO:0097156	fasciculation of motor neuron axon(GO:0097156)
0.0	0.0	GO:0035038	female pronucleus assembly(GO:0035038)
0.0	0.2	GO:0007602	phototransduction(GO:0007602)
0.0	0.2	GO:0002693	positive regulation of cellular extravasation(GO:0002693)
0.0	0.1	GO:0006030	chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032)
0.0	0.5	GO:0009250	glycogen biosynthetic process(GO:0005978) glucan biosynthetic process(GO:0009250)
0.0	0.7	GO:0022904	respiratory electron transport chain(GO:0022904)
0.0	0.5	GO:0007040	lysosome organization(GO:0007040) lytic vacuole organization(GO:0080171)
0.0	0.2	GO:2000480	negative regulation of cAMP-dependent protein kinase activity(GO:2000480)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.7	6.6	GO:0042567	insulin-like growth factor ternary complex(GO:0042567)
0.5	3.5	GO:0048237	rough endoplasmic reticulum lumen(GO:0048237)
0.5	2.8	GO:0097629	extrinsic component of omegasome membrane(GO:0097629)
0.5	5.1	GO:0045098	type III intermediate filament(GO:0045098)
0.4	3.9	GO:0005579	membrane attack complex(GO:0005579)
0.4	9.8	GO:0042627	chylomicron(GO:0042627)
0.4	1.9	GO:0044279	other organism cell membrane(GO:0044218) other organism membrane(GO:0044279)
0.3	10.4	GO:0080008	Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.3	2.8	GO:0097433	dense body(GO:0097433)
0.3	1.0	GO:0033596	TSC1-TSC2 complex(GO:0033596)
0.2	2.7	GO:0031931	TORC1 complex(GO:0031931)
0.2	1.2	GO:0030868	smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425)
0.2	1.0	GO:0043625	delta DNA polymerase complex(GO:0043625)
0.2	0.6	GO:0044753	amphisome(GO:0044753)
0.2	0.2	GO:0016942	insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454)
0.2	2.9	GO:0046581	intercellular canaliculus(GO:0046581)
0.1	3.6	GO:0005922	connexon complex(GO:0005922)
0.1	1.1	GO:0046696	lipopolysaccharide receptor complex(GO:0046696)
0.1	2.1	GO:0033179	proton-transporting V-type ATPase, V0 domain(GO:0033179)
0.1	0.6	GO:0044307	dendritic branch(GO:0044307)
0.1	1.7	GO:0034045	pre-autophagosomal structure membrane(GO:0034045)
0.1	0.9	GO:0045293	mRNA editing complex(GO:0045293)
0.1	1.3	GO:0071664	catenin-TCF7L2 complex(GO:0071664)
0.1	0.9	GO:0031265	CD95 death-inducing signaling complex(GO:0031265)
0.1	0.4	GO:0097543	ciliary inversin compartment(GO:0097543)
0.1	1.8	GO:0033391	chromatoid body(GO:0033391)
0.1	1.5	GO:0070852	cell body fiber(GO:0070852)
0.1	1.4	GO:0012510	trans-Golgi network transport vesicle membrane(GO:0012510)
0.1	0.8	GO:0005677	chromatin silencing complex(GO:0005677)
0.1	0.3	GO:0000221	vacuolar proton-transporting V-type ATPase, V1 domain(GO:0000221)
0.1	1.3	GO:0035102	PRC1 complex(GO:0035102)
0.1	0.6	GO:0030485	smooth muscle contractile fiber(GO:0030485)
0.1	0.6	GO:0030478	actin cap(GO:0030478)
0.1	0.5	GO:0035032	phosphatidylinositol 3-kinase complex, class III(GO:0035032)
0.1	4.3	GO:0046658	anchored component of plasma membrane(GO:0046658)
0.1	0.3	GO:0000839	Hrd1p ubiquitin ligase ERAD-L complex(GO:0000839)
0.1	0.4	GO:0019907	cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907)
0.0	0.5	GO:0042587	glycogen granule(GO:0042587)
0.0	2.9	GO:0009295	nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.0	0.2	GO:0070033	synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032) synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex(GO:0070033)
0.0	11.3	GO:0005777	peroxisome(GO:0005777) microbody(GO:0042579)
0.0	0.1	GO:0042721	mitochondrial inner membrane protein insertion complex(GO:0042721)
0.0	24.6	GO:0005789	endoplasmic reticulum membrane(GO:0005789)
0.0	0.4	GO:0090571	RNA polymerase II transcription repressor complex(GO:0090571)
0.0	0.4	GO:0031983	vesicle lumen(GO:0031983)
0.0	0.2	GO:0070022	transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.0	5.7	GO:0031225	anchored component of membrane(GO:0031225)
0.0	0.2	GO:0035976	AP1 complex(GO:0035976)
0.0	2.0	GO:0030118	clathrin coat(GO:0030118)
0.0	0.2	GO:0033269	internode region of axon(GO:0033269)
0.0	0.2	GO:0033503	HULC complex(GO:0033503)
0.0	0.7	GO:0035253	ciliary rootlet(GO:0035253)
0.0	0.3	GO:0005921	gap junction(GO:0005921)
0.0	0.5	GO:0005751	mitochondrial respiratory chain complex IV(GO:0005751)
0.0	0.3	GO:0016342	catenin complex(GO:0016342) growth cone membrane(GO:0032584)
0.0	1.7	GO:0031463	Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0	0.4	GO:0043196	varicosity(GO:0043196)
0.0	1.2	GO:0070469	respiratory chain(GO:0070469)
0.0	0.2	GO:0044294	dendritic growth cone(GO:0044294)
0.0	1.6	GO:0005581	collagen trimer(GO:0005581)
0.0	0.7	GO:0031201	SNARE complex(GO:0031201)
0.0	28.3	GO:0005739	mitochondrion(GO:0005739)
0.0	0.2	GO:0030670	phagocytic vesicle membrane(GO:0030670)
0.0	0.4	GO:0031588	nucleotide-activated protein kinase complex(GO:0031588)
0.0	0.2	GO:0032433	filopodium tip(GO:0032433)
0.0	0.3	GO:0005614	interstitial matrix(GO:0005614)
0.0	0.3	GO:0030057	desmosome(GO:0030057)
0.0	0.1	GO:0000813	ESCRT I complex(GO:0000813)
0.0	0.3	GO:0042101	T cell receptor complex(GO:0042101)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.4	5.6	GO:0016899	oxidoreductase activity, acting on the CH-OH group of donors, oxygen as acceptor(GO:0016899)
1.3	4.0	GO:0005333	acetylcholine transmembrane transporter activity(GO:0005277) norepinephrine transmembrane transporter activity(GO:0005333) acetate ester transmembrane transporter activity(GO:1901375)
1.2	8.3	GO:0052650	NADP-retinol dehydrogenase activity(GO:0052650)
1.2	7.1	GO:0060698	endoribonuclease inhibitor activity(GO:0060698)
1.0	4.2	GO:0005118	sevenless binding(GO:0005118)
1.0	6.1	GO:0060230	lipoprotein lipase activator activity(GO:0060230)
0.9	5.1	GO:0004850	uridine phosphorylase activity(GO:0004850)
0.8	3.2	GO:0070653	high-density lipoprotein particle receptor binding(GO:0070653)
0.7	4.9	GO:0005332	gamma-aminobutyric acid:sodium symporter activity(GO:0005332)
0.7	5.5	GO:0005534	galactose binding(GO:0005534)
0.7	2.7	GO:0004062	aryl sulfotransferase activity(GO:0004062)
0.6	3.6	GO:0004594	pantothenate kinase activity(GO:0004594)
0.6	4.0	GO:0016841	ammonia-lyase activity(GO:0016841)
0.5	3.2	GO:0051032	nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033)
0.5	2.7	GO:0008427	calcium-dependent protein kinase inhibitor activity(GO:0008427)
0.5	1.6	GO:0000179	rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179)
0.5	4.1	GO:0008508	bile acid:sodium symporter activity(GO:0008508)
0.5	1.4	GO:0004087	carbamoyl-phosphate synthase (ammonia) activity(GO:0004087) carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity(GO:0004088)
0.5	1.9	GO:0035651	AP-3 adaptor complex binding(GO:0035651)
0.5	2.3	GO:0038181	bile acid receptor activity(GO:0038181)
0.4	1.3	GO:0004616	phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
0.4	3.5	GO:0050649	testosterone 6-beta-hydroxylase activity(GO:0050649)
0.4	1.3	GO:0003963	RNA-3'-phosphate cyclase activity(GO:0003963)
0.4	1.2	GO:0002058	uracil binding(GO:0002058) pyrimidine nucleobase binding(GO:0002061)
0.4	1.9	GO:0004382	guanosine-diphosphatase activity(GO:0004382)
0.4	4.5	GO:0031730	CCR5 chemokine receptor binding(GO:0031730)
0.4	1.1	GO:0033149	FFAT motif binding(GO:0033149)
0.4	2.1	GO:0004022	alcohol dehydrogenase (NAD) activity(GO:0004022)
0.3	3.8	GO:0004322	ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.3	1.0	GO:0019807	aspartoacylase activity(GO:0019807)
0.3	2.2	GO:0015091	ferric iron transmembrane transporter activity(GO:0015091) trivalent inorganic cation transmembrane transporter activity(GO:0072510)
0.3	3.4	GO:0004499	N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.3	1.2	GO:0047016	cholest-5-ene-3-beta,7-alpha-diol 3-beta-dehydrogenase activity(GO:0047016)
0.3	0.9	GO:0004155	6,7-dihydropteridine reductase activity(GO:0004155)
0.3	3.6	GO:0030976	thiamine pyrophosphate binding(GO:0030976)
0.3	0.9	GO:0050508	glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.3	2.1	GO:0030375	thyroid hormone receptor coactivator activity(GO:0030375)
0.3	0.8	GO:0034632	retinol transporter activity(GO:0034632)
0.3	2.5	GO:0008474	palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.2	3.9	GO:0005243	gap junction channel activity(GO:0005243)
0.2	1.0	GO:0032422	purine-rich negative regulatory element binding(GO:0032422)
0.2	1.0	GO:0047275	glucosaminylgalactosylglucosylceramide beta-galactosyltransferase activity(GO:0047275)
0.2	0.9	GO:0015154	sucrose:proton symporter activity(GO:0008506) sucrose transmembrane transporter activity(GO:0008515) disaccharide transmembrane transporter activity(GO:0015154) oligosaccharide transmembrane transporter activity(GO:0015157)
0.2	1.0	GO:0070012	oligopeptidase activity(GO:0070012)
0.2	0.6	GO:0005457	GDP-fucose transmembrane transporter activity(GO:0005457) purine nucleotide-sugar transmembrane transporter activity(GO:0036080)
0.2	1.1	GO:0030294	receptor signaling protein tyrosine kinase inhibitor activity(GO:0030294)
0.2	1.8	GO:0008140	cAMP response element binding protein binding(GO:0008140)
0.2	0.8	GO:0004531	deoxyribonuclease II activity(GO:0004531)
0.2	1.0	GO:0032810	sterol response element binding(GO:0032810)
0.2	0.6	GO:0004329	formate-tetrahydrofolate ligase activity(GO:0004329)
0.2	3.4	GO:0016832	aldehyde-lyase activity(GO:0016832)
0.2	1.9	GO:0017162	aryl hydrocarbon receptor binding(GO:0017162)
0.2	0.6	GO:0004937	alpha1-adrenergic receptor activity(GO:0004937)
0.2	0.9	GO:0042289	MHC class II protein binding(GO:0042289)
0.1	0.9	GO:0001875	lipopolysaccharide receptor activity(GO:0001875)
0.1	0.9	GO:0042328	heparan sulfate N-acetylglucosaminyltransferase activity(GO:0042328)
0.1	2.6	GO:0008430	selenium binding(GO:0008430)
0.1	0.9	GO:0038049	glucocorticoid receptor activity(GO:0004883) transcription factor activity, ligand-activated RNA polymerase II transcription factor binding(GO:0038049) glucocorticoid-activated RNA polymerase II transcription factor binding transcription factor activity(GO:0038051)
0.1	0.4	GO:0001596	angiotensin type I receptor activity(GO:0001596)
0.1	1.9	GO:0016661	oxidoreductase activity, acting on other nitrogenous compounds as donors(GO:0016661)
0.1	0.7	GO:0004925	prolactin receptor activity(GO:0004925)
0.1	0.4	GO:0071820	N-box binding(GO:0071820)
0.1	1.7	GO:0004300	enoyl-CoA hydratase activity(GO:0004300)
0.1	1.1	GO:0004416	hydroxyacylglutathione hydrolase activity(GO:0004416)
0.1	1.1	GO:0043426	MRF binding(GO:0043426)
0.1	0.6	GO:0031699	beta-3 adrenergic receptor binding(GO:0031699)
0.1	8.9	GO:0043531	ADP binding(GO:0043531)
0.1	4.8	GO:0016712	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen(GO:0016712)
0.1	0.4	GO:0015152	glucose-6-phosphate transmembrane transporter activity(GO:0015152)
0.1	0.5	GO:0031708	endothelin B receptor binding(GO:0031708)
0.1	0.6	GO:0004528	phosphodiesterase I activity(GO:0004528)
0.1	0.9	GO:0042134	rRNA primary transcript binding(GO:0042134)
0.1	0.6	GO:0015319	sodium:inorganic phosphate symporter activity(GO:0015319)
0.1	0.6	GO:0034584	piRNA binding(GO:0034584)
0.1	3.3	GO:0001848	complement binding(GO:0001848)
0.1	0.7	GO:0008401	retinoic acid 4-hydroxylase activity(GO:0008401)
0.1	2.5	GO:0044548	S100 protein binding(GO:0044548)
0.1	5.8	GO:0008028	monocarboxylic acid transmembrane transporter activity(GO:0008028)
0.1	4.9	GO:0043539	protein serine/threonine kinase activator activity(GO:0043539)
0.1	0.7	GO:0060175	brain-derived neurotrophic factor-activated receptor activity(GO:0060175)
0.1	2.8	GO:0001871	pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.1	1.0	GO:0042500	aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.1	2.1	GO:0008553	hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.1	1.8	GO:0015643	toxic substance binding(GO:0015643)
0.1	1.5	GO:0045294	alpha-catenin binding(GO:0045294)
0.1	0.7	GO:0031433	telethonin binding(GO:0031433)
0.1	1.5	GO:0001206	transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.1	0.6	GO:0030549	acetylcholine receptor activator activity(GO:0030549)
0.1	1.4	GO:0004745	retinol dehydrogenase activity(GO:0004745)
0.1	1.5	GO:0004089	carbonate dehydratase activity(GO:0004089)
0.1	1.7	GO:0055106	ubiquitin-protein transferase regulator activity(GO:0055106)
0.1	0.7	GO:0034235	GPI anchor binding(GO:0034235)
0.1	0.7	GO:0034711	inhibin binding(GO:0034711)
0.1	2.3	GO:0005520	insulin-like growth factor binding(GO:0005520)
0.1	3.1	GO:0015020	glucuronosyltransferase activity(GO:0015020)
0.1	0.3	GO:0005008	hepatocyte growth factor-activated receptor activity(GO:0005008)
0.1	0.5	GO:0071532	ankyrin repeat binding(GO:0071532)
0.1	1.0	GO:0045236	CXCR chemokine receptor binding(GO:0045236)
0.1	0.5	GO:0043423	3-phosphoinositide-dependent protein kinase binding(GO:0043423)
0.1	0.3	GO:0015321	sodium-dependent phosphate transmembrane transporter activity(GO:0015321)
0.1	0.2	GO:0008330	protein tyrosine/threonine phosphatase activity(GO:0008330)
0.1	0.3	GO:0004740	pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.1	1.1	GO:0015143	urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.1	0.3	GO:0016842	amidine-lyase activity(GO:0016842)
0.1	0.4	GO:0004792	thiosulfate sulfurtransferase activity(GO:0004792)
0.1	1.8	GO:0043325	phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.1	0.2	GO:0010698	acetyltransferase activator activity(GO:0010698)
0.1	1.8	GO:0042975	peroxisome proliferator activated receptor binding(GO:0042975)
0.1	0.3	GO:0052796	exo-alpha-sialidase activity(GO:0004308) alpha-sialidase activity(GO:0016997) exo-alpha-(2->3)-sialidase activity(GO:0052794) exo-alpha-(2->6)-sialidase activity(GO:0052795) exo-alpha-(2->8)-sialidase activity(GO:0052796)
0.1	1.0	GO:0008190	eukaryotic initiation factor 4E binding(GO:0008190)
0.1	0.5	GO:0070290	N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.1	0.4	GO:0005119	smoothened binding(GO:0005119) hedgehog receptor activity(GO:0008158)
0.1	0.4	GO:0004028	3-chloroallyl aldehyde dehydrogenase activity(GO:0004028)
0.1	4.2	GO:0038024	cargo receptor activity(GO:0038024)
0.1	0.2	GO:0034597	phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316) phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity(GO:0034597)
0.1	0.6	GO:0070739	protein-glutamic acid ligase activity(GO:0070739)
0.0	0.3	GO:0004826	phenylalanine-tRNA ligase activity(GO:0004826)
0.0	2.1	GO:0016790	thiolester hydrolase activity(GO:0016790)
0.0	0.3	GO:0004556	alpha-amylase activity(GO:0004556)
0.0	0.5	GO:0035473	lipase binding(GO:0035473)
0.0	1.7	GO:0080025	phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.0	0.9	GO:0004622	lysophospholipase activity(GO:0004622)
0.0	1.0	GO:0032794	GTPase activating protein binding(GO:0032794)
0.0	1.6	GO:0001223	transcription coactivator binding(GO:0001223)
0.0	0.3	GO:0019784	NEDD8-specific protease activity(GO:0019784)
0.0	0.5	GO:0004185	serine-type carboxypeptidase activity(GO:0004185)
0.0	0.6	GO:0003906	DNA-(apurinic or apyrimidinic site) lyase activity(GO:0003906)
0.0	0.9	GO:0004190	aspartic-type endopeptidase activity(GO:0004190)
0.0	0.5	GO:0047372	acylglycerol lipase activity(GO:0047372)
0.0	0.8	GO:0070513	death domain binding(GO:0070513)
0.0	1.2	GO:0050136	NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0	1.1	GO:0051537	2 iron, 2 sulfur cluster binding(GO:0051537)
0.0	0.8	GO:0016646	oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor(GO:0016646)
0.0	0.2	GO:0033192	calmodulin-dependent protein phosphatase activity(GO:0033192)
0.0	0.5	GO:0015093	ferrous iron transmembrane transporter activity(GO:0015093)
0.0	0.5	GO:0019911	structural constituent of myelin sheath(GO:0019911)
0.0	0.8	GO:0016805	dipeptidase activity(GO:0016805)
0.0	0.1	GO:0097604	temperature-gated cation channel activity(GO:0097604)
0.0	0.2	GO:0042030	ATPase inhibitor activity(GO:0042030)
0.0	0.5	GO:0043522	leucine zipper domain binding(GO:0043522)
0.0	0.5	GO:0019531	oxalate transmembrane transporter activity(GO:0019531)
0.0	0.2	GO:0047288	monosialoganglioside sialyltransferase activity(GO:0047288)
0.0	0.2	GO:0070915	lysophosphatidic acid receptor activity(GO:0070915)
0.0	0.3	GO:0046790	virion binding(GO:0046790)
0.0	0.9	GO:0005035	tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.0	5.4	GO:0004252	serine-type endopeptidase activity(GO:0004252)
0.0	1.7	GO:0005070	SH3/SH2 adaptor activity(GO:0005070)
0.0	1.3	GO:0016831	carboxy-lyase activity(GO:0016831)
0.0	0.2	GO:0005005	transmembrane-ephrin receptor activity(GO:0005005)
0.0	0.3	GO:0003997	acyl-CoA oxidase activity(GO:0003997)
0.0	0.3	GO:0048101	calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117) calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.0	0.1	GO:0003953	NAD+ nucleosidase activity(GO:0003953)
0.0	0.1	GO:0030156	benzodiazepine receptor binding(GO:0030156)
0.0	0.3	GO:0038062	protein tyrosine kinase collagen receptor activity(GO:0038062)
0.0	0.7	GO:0004129	cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0	0.8	GO:0017166	vinculin binding(GO:0017166)
0.0	0.2	GO:0030275	LRR domain binding(GO:0030275)
0.0	0.3	GO:0004806	triglyceride lipase activity(GO:0004806)
0.0	0.8	GO:0008395	steroid hydroxylase activity(GO:0008395)
0.0	0.6	GO:0070530	K63-linked polyubiquitin binding(GO:0070530)
0.0	0.1	GO:0033038	bitter taste receptor activity(GO:0033038)
0.0	0.6	GO:0031434	mitogen-activated protein kinase kinase binding(GO:0031434)
0.0	0.8	GO:0050750	low-density lipoprotein particle receptor binding(GO:0050750)
0.0	1.2	GO:0015485	cholesterol binding(GO:0015485)
0.0	0.9	GO:0005484	SNAP receptor activity(GO:0005484)
0.0	0.1	GO:0004969	histamine receptor activity(GO:0004969)
0.0	0.2	GO:0003956	NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956)
0.0	0.2	GO:0070679	inositol 1,4,5 trisphosphate binding(GO:0070679)
0.0	0.9	GO:0005160	transforming growth factor beta receptor binding(GO:0005160)
0.0	0.3	GO:0070411	I-SMAD binding(GO:0070411)
0.0	0.5	GO:0004115	3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0	0.2	GO:0016176	superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.0	0.1	GO:0004647	phosphoserine phosphatase activity(GO:0004647)
0.0	0.3	GO:1990381	ubiquitin-specific protease binding(GO:1990381)
0.0	0.6	GO:0070064	proline-rich region binding(GO:0070064)
0.0	0.3	GO:0036442	hydrogen-exporting ATPase activity(GO:0036442)
0.0	0.1	GO:0047498	calcium-dependent phospholipase A2 activity(GO:0047498)
0.0	0.2	GO:0090482	vitamin transmembrane transporter activity(GO:0090482)
0.0	0.1	GO:0015272	ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.0	0.9	GO:0001205	transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.0	0.4	GO:0001221	transcription cofactor binding(GO:0001221)
0.0	0.1	GO:0005113	patched binding(GO:0005113)
0.0	0.6	GO:0051879	Hsp90 protein binding(GO:0051879)
0.0	0.9	GO:0004722	protein serine/threonine phosphatase activity(GO:0004722)
0.0	0.4	GO:0071837	HMG box domain binding(GO:0071837)
0.0	0.3	GO:0005212	structural constituent of eye lens(GO:0005212)
0.0	0.1	GO:0008020	G-protein coupled photoreceptor activity(GO:0008020)
0.0	0.1	GO:0004568	chitinase activity(GO:0004568)
0.0	0.2	GO:0005540	hyaluronic acid binding(GO:0005540)
0.0	0.8	GO:0016706	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors(GO:0016706)
0.0	0.1	GO:0016308	1-phosphatidylinositol-4-phosphate 5-kinase activity(GO:0016308)
0.0	1.1	GO:0004197	cysteine-type endopeptidase activity(GO:0004197)
0.0	0.2	GO:0004862	cAMP-dependent protein kinase inhibitor activity(GO:0004862)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.4	4.5	ST TYPE I INTERFERON PATHWAY	Type I Interferon (alpha/beta IFN) Pathway
0.1	2.4	PID ERB GENOMIC PATHWAY	Validated nuclear estrogen receptor beta network
0.1	2.9	PID INTEGRIN5 PATHWAY	Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.1	9.8	PID TAP63 PATHWAY	Validated transcriptional targets of TAp63 isoforms
0.1	5.1	PID RXR VDR PATHWAY	RXR and RAR heterodimerization with other nuclear receptor
0.1	6.5	PID HNF3B PATHWAY	FOXA2 and FOXA3 transcription factor networks
0.1	1.9	ST G ALPHA S PATHWAY	G alpha s Pathway
0.1	3.6	PID RET PATHWAY	Signaling events regulated by Ret tyrosine kinase
0.1	8.2	PID MYC REPRESS PATHWAY	Validated targets of C-MYC transcriptional repression
0.1	4.6	PID IGF1 PATHWAY	IGF1 pathway
0.1	4.2	PID LKB1 PATHWAY	LKB1 signaling events
0.1	0.6	PID INTEGRIN3 PATHWAY	Beta3 integrin cell surface interactions
0.1	1.4	PID CIRCADIAN PATHWAY	Circadian rhythm pathway
0.1	0.9	PID PI3KCI AKT PATHWAY	Class I PI3K signaling events mediated by Akt
0.1	1.6	SA CASPASE CASCADE	Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.1	1.4	PID WNT CANONICAL PATHWAY	Canonical Wnt signaling pathway
0.0	1.6	PID ALK1 PATHWAY	ALK1 signaling events
0.0	1.4	PID ECADHERIN KERATINOCYTE PATHWAY	E-cadherin signaling in keratinocytes
0.0	1.7	PID INSULIN PATHWAY	Insulin Pathway
0.0	2.8	PID FGF PATHWAY	FGF signaling pathway
0.0	3.4	PID HIF1 TFPATHWAY	HIF-1-alpha transcription factor network
0.0	0.8	PID LPA4 PATHWAY	LPA4-mediated signaling events
0.0	0.8	PID UPA UPAR PATHWAY	Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.0	0.9	PID INTEGRIN2 PATHWAY	Beta2 integrin cell surface interactions
0.0	0.3	PID IL5 PATHWAY	IL5-mediated signaling events
0.0	0.7	PID FOXM1 PATHWAY	FOXM1 transcription factor network
0.0	0.8	PID HIV NEF PATHWAY	HIV-1 Nef: Negative effector of Fas and TNF-alpha
0.0	1.5	PID REG GR PATHWAY	Glucocorticoid receptor regulatory network
0.0	1.1	PID ATF2 PATHWAY	ATF-2 transcription factor network
0.0	0.4	PID IFNG PATHWAY	IFN-gamma pathway
0.0	0.8	PID HNF3A PATHWAY	FOXA1 transcription factor network
0.0	0.5	PID ARF 3PATHWAY	Arf1 pathway
0.0	0.7	PID PTP1B PATHWAY	Signaling events mediated by PTP1B
0.0	0.4	PID HEDGEHOG 2PATHWAY	Signaling events mediated by the Hedgehog family
0.0	0.7	PID BMP PATHWAY	BMP receptor signaling
0.0	0.3	PID INTEGRIN A9B1 PATHWAY	Alpha9 beta1 integrin signaling events
0.0	0.7	PID AJDISS 2PATHWAY	Posttranslational regulation of adherens junction stability and dissassembly
0.0	0.2	PID BETA CATENIN DEG PATHWAY	Degradation of beta catenin
0.0	0.2	ST JNK MAPK PATHWAY	JNK MAPK Pathway
0.0	0.2	PID EPHRINB REV PATHWAY	Ephrin B reverse signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.6	4.8	REACTOME XENOBIOTICS	Genes involved in Xenobiotics
0.7	5.8	REACTOME CREATION OF C4 AND C2 ACTIVATORS	Genes involved in Creation of C4 and C2 activators
0.5	5.9	REACTOME RECYCLING OF BILE ACIDS AND SALTS	Genes involved in Recycling of bile acids and salts
0.3	6.4	REACTOME PYRIMIDINE CATABOLISM	Genes involved in Pyrimidine catabolism
0.3	4.0	REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT	Genes involved in Organic cation/anion/zwitterion transport
0.3	4.6	REACTOME VITAMIN B5 PANTOTHENATE METABOLISM	Genes involved in Vitamin B5 (pantothenate) metabolism
0.3	4.5	REACTOME IL 6 SIGNALING	Genes involved in Interleukin-6 signaling
0.3	3.9	REACTOME ANDROGEN BIOSYNTHESIS	Genes involved in Androgen biosynthesis
0.2	7.1	REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT	Genes involved in Chylomicron-mediated lipid transport
0.2	4.9	REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS	Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.2	5.0	REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM	Genes involved in Branched-chain amino acid catabolism
0.2	3.9	REACTOME COMPLEMENT CASCADE	Genes involved in Complement cascade
0.2	2.5	REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS	Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.2	3.6	REACTOME GAP JUNCTION ASSEMBLY	Genes involved in Gap junction assembly
0.1	3.6	REACTOME PEROXISOMAL LIPID METABOLISM	Genes involved in Peroxisomal lipid metabolism
0.1	2.6	REACTOME FGFR4 LIGAND BINDING AND ACTIVATION	Genes involved in FGFR4 ligand binding and activation
0.1	1.1	REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1	Genes involved in IKK complex recruitment mediated by RIP1
0.1	2.0	REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 7ALPHA HYDROXYCHOLESTEROL	Genes involved in Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol
0.1	2.2	REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS	Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.1	1.4	REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK	Genes involved in Regulation of Rheb GTPase activity by AMPK
0.1	4.4	REACTOME PIP3 ACTIVATES AKT SIGNALING	Genes involved in PIP3 activates AKT signaling
0.1	1.2	REACTOME IRAK1 RECRUITS IKK COMPLEX	Genes involved in IRAK1 recruits IKK complex
0.1	5.4	REACTOME IRON UPTAKE AND TRANSPORT	Genes involved in Iron uptake and transport
0.1	1.9	REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE	Genes involved in Synthesis of PIPs at the early endosome membrane
0.1	0.6	REACTOME REGULATION OF AMPK ACTIVITY VIA LKB1	Genes involved in Regulation of AMPK activity via LKB1
0.1	2.7	REACTOME ADHERENS JUNCTIONS INTERACTIONS	Genes involved in Adherens junctions interactions
0.1	4.1	REACTOME PHASE1 FUNCTIONALIZATION OF COMPOUNDS	Genes involved in Phase 1 - Functionalization of compounds
0.1	7.7	REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY	Genes involved in Nuclear Receptor transcription pathway
0.1	2.9	REACTOME CELL CELL JUNCTION ORGANIZATION	Genes involved in Cell-cell junction organization
0.1	1.6	REACTOME NRIF SIGNALS CELL DEATH FROM THE NUCLEUS	Genes involved in NRIF signals cell death from the nucleus
0.1	1.8	REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA	Genes involved in Circadian Repression of Expression by REV-ERBA
0.1	0.9	REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS	Genes involved in Extrinsic Pathway for Apoptosis
0.1	12.4	REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES	Genes involved in Metabolism of amino acids and derivatives
0.0	1.3	REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS	Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0	1.7	REACTOME HS GAG BIOSYNTHESIS	Genes involved in HS-GAG biosynthesis
0.0	1.0	REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX	Genes involved in Degradation of the extracellular matrix
0.0	1.9	REACTOME PYRUVATE METABOLISM AND CITRIC ACID TCA CYCLE	Genes involved in Pyruvate metabolism and Citric Acid (TCA) cycle
0.0	0.8	REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS	Genes involved in Regulation of gene expression in beta cells
0.0	0.3	REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF RAS	Genes involved in CREB phosphorylation through the activation of Ras
0.0	0.5	REACTOME ACTIVATION OF CHAPERONES BY ATF6 ALPHA	Genes involved in Activation of Chaperones by ATF6-alpha
0.0	0.6	REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS	Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0	0.4	REACTOME ROLE OF DCC IN REGULATING APOPTOSIS	Genes involved in Role of DCC in regulating apoptosis
0.0	0.5	REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS	Genes involved in Facilitative Na+-independent glucose transporters
0.0	3.4	REACTOME INTEGRIN CELL SURFACE INTERACTIONS	Genes involved in Integrin cell surface interactions
0.0	0.5	REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS	Genes involved in Activation of the AP-1 family of transcription factors
0.0	1.3	REACTOME NCAM1 INTERACTIONS	Genes involved in NCAM1 interactions
0.0	0.2	REACTOME OLFACTORY SIGNALING PATHWAY	Genes involved in Olfactory Signaling Pathway
0.0	1.1	REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS	Genes involved in Sphingolipid de novo biosynthesis
0.0	0.2	REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.0	0.8	REACTOME SIGNALING BY BMP	Genes involved in Signaling by BMP
0.0	0.3	REACTOME REGULATION OF BETA CELL DEVELOPMENT	Genes involved in Regulation of beta-cell development
0.0	0.9	REACTOME GLUCONEOGENESIS	Genes involved in Gluconeogenesis
0.0	0.7	REACTOME NGF SIGNALLING VIA TRKA FROM THE PLASMA MEMBRANE	Genes involved in NGF signalling via TRKA from the plasma membrane
0.0	0.6	REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF CAMKII	Genes involved in CREB phosphorylation through the activation of CaMKII
0.0	0.7	REACTOME AMINE LIGAND BINDING RECEPTORS	Genes involved in Amine ligand-binding receptors
0.0	0.7	REACTOME GROWTH HORMONE RECEPTOR SIGNALING	Genes involved in Growth hormone receptor signaling
0.0	0.9	REACTOME COLLAGEN FORMATION	Genes involved in Collagen formation
0.0	1.6	REACTOME RNA POL I RNA POL III AND MITOCHONDRIAL TRANSCRIPTION	Genes involved in RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription
0.0	0.2	REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING	Genes involved in Role of second messengers in netrin-1 signaling
0.0	0.2	REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION	Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.0	0.1	REACTOME OPSINS	Genes involved in Opsins
0.0	0.2	REACTOME GAP JUNCTION TRAFFICKING	Genes involved in Gap junction trafficking
0.0	0.2	REACTOME P2Y RECEPTORS	Genes involved in P2Y receptors
0.0	0.3	REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS	Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0	0.6	REACTOME METABOLISM OF VITAMINS AND COFACTORS	Genes involved in Metabolism of vitamins and cofactors
0.0	0.3	REACTOME SIGNALING BY HIPPO	Genes involved in Signaling by Hippo

Results for Foxp2_Foxp3

Z-value: 0.63

Motif logo

Transcription factors associated with Foxp2_Foxp3

Activity-expression correlation:

Activity profile of Foxp2_Foxp3 motif

Sorted Z-values of Foxp2_Foxp3 motif

Top targets:

Network of associatons between targets according to the STRING database.

First level regulatory network of Foxp2_Foxp3

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: