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GSE58827: Dynamics of the Mouse Liver

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Results for Gata2_Gata1

Z-value: 5.28

Motif logo

Transcription factors associated with Gata2_Gata1

Gene Symbol Gene ID Gene Info
ENSMUSG00000015053.15 GATA binding protein 2
ENSMUSG00000031162.15 GATA binding protein 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Gata1mm39_v1_chrX_-_7834057_78341490.879.3e-12Click!
Gata2mm39_v1_chr6_+_88175312_881753160.812.7e-09Click!

Activity profile of Gata2_Gata1 motif

Sorted Z-values of Gata2_Gata1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr8_+_85428059 95.47 ENSMUST00000238364.2
ENSMUST00000238562.2
ENSMUST00000037165.6
lymphoblastomic leukemia 1
chr17_-_26417982 88.11 ENSMUST00000142410.2
ENSMUST00000120333.8
ENSMUST00000039113.14
protein disulfide isomerase associated 2
chr6_+_30639217 87.16 ENSMUST00000031806.10
carboxypeptidase A1, pancreatic
chr17_-_28779678 87.07 ENSMUST00000114785.3
ENSMUST00000025062.5
colipase, pancreatic
chr2_+_84810802 86.84 ENSMUST00000028467.6
proteoglycan 2, bone marrow
chr1_-_132295617 82.84 ENSMUST00000142609.8
transmembrane and coiled-coil domains 2
chr17_+_37180437 81.60 ENSMUST00000060524.11
tripartite motif-containing 10
chr4_-_46404224 75.96 ENSMUST00000107764.9
hemogen
chr9_+_20940669 74.58 ENSMUST00000001040.7
ENSMUST00000215077.2
intercellular adhesion molecule 4, Landsteiner-Wiener blood group
chr6_+_41369290 72.20 ENSMUST00000049079.9
predicted gene 5771
chr15_-_103159892 71.17 ENSMUST00000133600.8
ENSMUST00000134554.2
ENSMUST00000156927.8
nuclear factor, erythroid derived 2
chr6_+_41435846 69.62 ENSMUST00000031910.8
protease, serine 1 (trypsin 1)
chr6_+_41279199 67.40 ENSMUST00000031913.5
trypsin 4
chr2_-_120867529 67.10 ENSMUST00000102490.10
erythrocyte membrane protein band 4.2
chr4_-_137157824 65.91 ENSMUST00000102522.5
chymotrypsin-like elastase family, member 3B
chr15_-_103160082 65.35 ENSMUST00000149111.8
ENSMUST00000132836.8
nuclear factor, erythroid derived 2
chr9_-_44253588 63.97 ENSMUST00000215091.2
hydroxymethylbilane synthase
chr6_-_41681273 63.50 ENSMUST00000031899.14
Kell blood group
chr10_-_62178453 62.21 ENSMUST00000143179.2
ENSMUST00000130422.8
hexokinase 1
chr9_-_21874802 59.36 ENSMUST00000006397.7
erythropoietin receptor
chr6_+_30541581 59.10 ENSMUST00000096066.5
carboxypeptidase A2, pancreatic
chr4_+_134591847 58.47 ENSMUST00000030627.8
Rh blood group, D antigen
chr11_-_102360664 53.94 ENSMUST00000103086.4
integrin alpha 2b
chr2_-_120867232 52.89 ENSMUST00000023987.6
erythrocyte membrane protein band 4.2
chr2_+_103788321 48.84 ENSMUST00000156813.8
ENSMUST00000170926.8
LIM domain only 2
chr11_+_95227836 47.57 ENSMUST00000037502.7
family with sequence similarity 117, member A
chr7_-_98887770 43.99 ENSMUST00000064231.8
monoacylglycerol O-acyltransferase 2
chr17_-_35304582 43.87 ENSMUST00000038507.7
lymphocyte antigen 6 complex, locus G6F
chr6_+_41331039 43.20 ENSMUST00000072103.7
trypsin 10
chr8_+_85428391 40.67 ENSMUST00000238338.2
lymphoblastomic leukemia 1
chr9_-_44253630 39.84 ENSMUST00000097558.5
hydroxymethylbilane synthase
chr19_-_6996791 39.28 ENSMUST00000040772.9
fermitin family member 3
chrX_-_106446928 38.48 ENSMUST00000033591.6
integral membrane protein 2A
chr11_-_83177548 36.43 ENSMUST00000163961.3
schlafen 14
chr6_-_41291634 35.94 ENSMUST00000064324.12
trypsin 5
chr6_+_41498716 35.02 ENSMUST00000070380.5
protease, serine 2
chr6_+_86055018 34.54 ENSMUST00000205034.3
ENSMUST00000203724.3
adducin 2 (beta)
chr16_+_38182569 34.48 ENSMUST00000023494.13
ENSMUST00000114739.2
popeye domain containing 2
chr7_+_99184645 33.99 ENSMUST00000098266.9
ENSMUST00000179755.8
arrestin, beta 1
chr11_+_32226400 33.93 ENSMUST00000020531.9
hemoglobin X, alpha-like embryonic chain in Hba complex
chr19_-_6996696 33.76 ENSMUST00000236188.2
fermitin family member 3
chrX_+_149330371 31.32 ENSMUST00000066337.13
ENSMUST00000112715.2
aminolevulinic acid synthase 2, erythroid
chr8_-_86107593 28.81 ENSMUST00000122452.8
myosin light chain kinase 3
chr6_+_86055048 27.44 ENSMUST00000032069.8
adducin 2 (beta)
chr2_-_153083322 27.31 ENSMUST00000056924.14
pleiomorphic adenoma gene-like 2
chr14_-_70945434 27.08 ENSMUST00000228346.2
exportin 7
chr17_-_33932346 25.93 ENSMUST00000173392.2
membrane associated ring-CH-type finger 2
chrX_-_7830405 23.68 ENSMUST00000128449.2
GATA binding protein 1
chr3_-_107129038 23.42 ENSMUST00000029504.9
chymosin
chr7_+_28240262 22.74 ENSMUST00000119180.4
syncollin
chr11_+_32226893 21.84 ENSMUST00000145569.2
hemoglobin X, alpha-like embryonic chain in Hba complex
chr4_-_119047202 21.53 ENSMUST00000239029.2
ENSMUST00000138395.9
ENSMUST00000156746.3
erythroblast membrane-associated protein
chr18_-_78166595 21.00 ENSMUST00000091813.12
solute carrier family 14 (urea transporter), member 1
chr11_+_4936824 19.81 ENSMUST00000109897.8
ENSMUST00000009234.16
adaptor protein complex AP-1, beta 1 subunit
chr14_+_26722319 19.58 ENSMUST00000035433.10
homeobox gene expressed in ES cells
chr11_-_99328969 19.26 ENSMUST00000017743.3
keratin 20
chr18_-_78166539 18.88 ENSMUST00000160292.8
solute carrier family 14 (urea transporter), member 1
chr2_+_72306503 18.82 ENSMUST00000102691.11
ENSMUST00000157019.2
cell division cycle associated 7
chr3_-_20296337 18.55 ENSMUST00000001921.3
carboxypeptidase A3, mast cell
chr19_-_6065181 18.37 ENSMUST00000236537.2
ENSMUST00000025891.11
calpain 1
chr5_+_115604321 18.14 ENSMUST00000145785.8
ENSMUST00000031495.11
ENSMUST00000112071.8
ENSMUST00000125568.2
phospholipase A2, group IB, pancreas
chr9_-_57743989 17.41 ENSMUST00000164010.8
ENSMUST00000171444.8
ENSMUST00000098686.4
AT rich interactive domain 3B (BRIGHT-like)
chrX_+_92718695 17.41 ENSMUST00000045898.4
phosphate cytidylyltransferase 1, choline, beta isoform
chr4_-_119047167 17.40 ENSMUST00000030396.15
erythroblast membrane-associated protein
chr17_-_31363245 17.15 ENSMUST00000024826.8
trefoil factor 2 (spasmolytic protein 1)
chr19_-_6065415 16.64 ENSMUST00000237519.2
calpain 1
chr11_-_115968745 16.31 ENSMUST00000156545.2
ENSMUST00000075036.9
ENSMUST00000106451.8
unc-13 homolog D
chr15_+_57849269 16.05 ENSMUST00000050374.3
family with sequence similarity 83, member A
chr11_+_70529944 15.99 ENSMUST00000055184.7
ENSMUST00000108551.3
glycoprotein 1b, alpha polypeptide
chr4_-_137137088 15.69 ENSMUST00000024200.7
chymotrypsin-like elastase family, member 3A
chr17_-_35285146 15.47 ENSMUST00000174190.2
ENSMUST00000097337.8
megakaryocyte and platelet inhibitory receptor G6b
chr10_-_62163444 15.41 ENSMUST00000139228.8
hexokinase 1
chr4_-_87724533 15.24 ENSMUST00000126353.8
ENSMUST00000149357.8
myeloid/lymphoid or mixed-lineage leukemia; translocated to, 3
chr11_+_70396070 14.77 ENSMUST00000019063.3
transmembrane 4 superfamily member 5
chr6_-_136899167 14.65 ENSMUST00000032343.7
endoplasmic reticulum protein 27
chr10_+_79855454 14.49 ENSMUST00000043311.7
Rho GTPase activating protein 45
chr11_-_115968373 14.28 ENSMUST00000174822.8
unc-13 homolog D
chr8_-_86091946 14.14 ENSMUST00000034133.14
myosin light chain kinase 3
chr3_+_108272205 13.93 ENSMUST00000090563.7
myosin binding protein H-like
chr8_-_86091970 13.48 ENSMUST00000121972.8
myosin light chain kinase 3
chr4_-_119047146 13.45 ENSMUST00000124626.9
erythroblast membrane-associated protein
chr4_-_119047180 13.43 ENSMUST00000150864.3
ENSMUST00000141227.9
erythroblast membrane-associated protein
chr6_-_136918885 13.42 ENSMUST00000111891.4
Rho, GDP dissociation inhibitor (GDI) beta
chr1_-_173161069 13.40 ENSMUST00000038227.6
atypical chemokine receptor 1 (Duffy blood group)
chr16_+_58490625 12.78 ENSMUST00000060077.7
coproporphyrinogen oxidase
chr6_-_136918495 12.74 ENSMUST00000111892.8
Rho, GDP dissociation inhibitor (GDI) beta
chr4_-_59438633 12.67 ENSMUST00000040166.14
ENSMUST00000107544.2
sushi domain containing 1
chr5_-_73349191 12.66 ENSMUST00000176910.3
FRY like transcription coactivator
chr6_+_87405968 12.43 ENSMUST00000032125.7
bone morphogenetic protein 10
chr6_-_136918844 11.95 ENSMUST00000204934.2
Rho, GDP dissociation inhibitor (GDI) beta
chr10_-_80257681 11.95 ENSMUST00000156244.2
transcription factor 3
chr9_+_66257747 11.78 ENSMUST00000042824.13
HECT and RLD domain containing E3 ubiquitin protein ligase family member 1
chr6_-_136918671 11.65 ENSMUST00000032344.12
Rho, GDP dissociation inhibitor (GDI) beta
chr11_-_115968576 11.57 ENSMUST00000106450.8
unc-13 homolog D
chr3_-_14873406 10.52 ENSMUST00000181860.8
ENSMUST00000144327.3
carbonic anhydrase 1
chr15_+_80507671 10.04 ENSMUST00000043149.9
GRB2-related adaptor protein 2
chr11_-_115967873 9.94 ENSMUST00000153408.8
unc-13 homolog D
chr2_+_84867554 9.51 ENSMUST00000077798.13
structure specific recognition protein 1
chr7_+_110372860 9.41 ENSMUST00000143786.2
adenosine monophosphate deaminase 3
chr10_-_80269436 9.15 ENSMUST00000105346.10
ENSMUST00000020377.13
ENSMUST00000105340.8
ENSMUST00000020379.13
ENSMUST00000105344.8
ENSMUST00000105342.8
ENSMUST00000105345.10
ENSMUST00000105343.8
transcription factor 3
chr8_+_121215155 9.02 ENSMUST00000034279.16
genetic suppressor element 1, coiled-coil protein
chr6_+_125529911 8.65 ENSMUST00000112254.8
ENSMUST00000112253.6
Von Willebrand factor
chr7_-_119058489 8.52 ENSMUST00000207887.3
ENSMUST00000239424.2
ENSMUST00000033255.8
glycoprotein 2 (zymogen granule membrane)
chr15_-_98505508 8.50 ENSMUST00000096224.6
adenylate cyclase 6
chr4_-_87724512 8.42 ENSMUST00000148059.2
myeloid/lymphoid or mixed-lineage leukemia; translocated to, 3
chr19_-_6065799 8.34 ENSMUST00000235138.2
calpain 1
chr15_+_76788270 8.12 ENSMUST00000004072.10
ENSMUST00000229183.2
ribosomal protein L8
chr2_+_84867783 8.06 ENSMUST00000168266.8
ENSMUST00000130729.3
structure specific recognition protein 1
chr1_-_138103021 7.97 ENSMUST00000182755.8
ENSMUST00000193650.2
ENSMUST00000182283.8
protein tyrosine phosphatase, receptor type, C
chr7_-_4400704 7.77 ENSMUST00000108590.4
ENSMUST00000206928.2
glycoprotein 6 (platelet)
chr1_-_45965661 7.69 ENSMUST00000186804.2
ENSMUST00000187406.7
ENSMUST00000187420.7
solute carrier family 40 (iron-regulated transporter), member 1
chr2_-_156848923 7.40 ENSMUST00000146413.8
ENSMUST00000103129.9
ENSMUST00000103130.8
DSN1 homolog, MIS12 kinetochore complex component
chr7_+_110226857 7.35 ENSMUST00000033054.10
adrenomedullin
chr11_+_4959515 7.26 ENSMUST00000101613.3
adaptor protein complex AP-1, beta 1 subunit
chr8_+_71047110 7.16 ENSMUST00000019283.10
ENSMUST00000210005.2
myo-inositol 1-phosphate synthase A1
chr2_-_73316053 6.99 ENSMUST00000102680.8
WAS/WASL interacting protein family, member 1
chr15_+_55171138 5.87 ENSMUST00000023053.12
ENSMUST00000110217.10
collagen, type XIV, alpha 1
chr8_+_121264161 5.74 ENSMUST00000118136.2
genetic suppressor element 1, coiled-coil protein
chr10_+_39009951 5.70 ENSMUST00000019991.8
tubulin, epsilon 1
chr14_-_54891073 5.56 ENSMUST00000126166.8
ENSMUST00000141453.8
ENSMUST00000150371.8
ENSMUST00000123875.2
ENSMUST00000022794.14
ENSMUST00000148754.10
apoptotic chromatin condensation inducer 1
chr1_-_138102972 5.28 ENSMUST00000195533.6
ENSMUST00000183301.8
protein tyrosine phosphatase, receptor type, C
chr4_+_40920047 5.04 ENSMUST00000030122.5
serine peptidase inhibitor, Kazal type 4
chr5_+_32616187 5.03 ENSMUST00000015100.15
protein phosphatase 1 catalytic subunit beta
chr15_+_102392586 4.97 ENSMUST00000229061.2
poly(rC) binding protein 2
chr9_+_48073296 4.93 ENSMUST00000216998.2
ENSMUST00000215780.2
neurexophilin and PC-esterase domain family, member 4
chr5_+_64969679 4.82 ENSMUST00000166409.6
ENSMUST00000197879.2
Kruppel-like factor 3 (basic)
chr16_+_44914397 4.73 ENSMUST00000061050.6
coiled-coil domain containing 80
chr9_-_44624496 4.71 ENSMUST00000144251.8
ENSMUST00000156918.8
pleckstrin homology like domain, family B, member 1
chr1_-_160134873 4.34 ENSMUST00000193185.6
RAB GTPase activating protein 1-like
chr11_-_94133527 4.27 ENSMUST00000061469.4
WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2
chr10_+_5543769 4.20 ENSMUST00000051809.10
myc target 1
chr12_-_69939931 4.09 ENSMUST00000049239.8
ENSMUST00000110570.8
mitogen-activated protein kinase kinase kinase kinase 5
chr9_-_65734826 4.01 ENSMUST00000159109.2
zinc finger protein 609
chr3_-_75177378 3.96 ENSMUST00000039047.5
serine (or cysteine) peptidase inhibitor, clade I, member 2
chr11_-_75060345 3.65 ENSMUST00000055619.5
hypermethylated in cancer 1
chr17_+_71511642 3.63 ENSMUST00000126681.8
lipin 2
chr16_+_44913974 3.57 ENSMUST00000099498.10
coiled-coil domain containing 80
chr13_-_73848807 3.56 ENSMUST00000022048.6
solute carrier family 6 (neurotransmitter transporter), member 19
chr17_-_82045800 3.44 ENSMUST00000235015.2
ENSMUST00000163123.3
solute carrier family 8 (sodium/calcium exchanger), member 1
chr15_-_38518458 3.38 ENSMUST00000127848.2
antizyme inhibitor 1
chr9_+_56982622 3.36 ENSMUST00000167715.8
transcriptional regulator, SIN3A (yeast)
chr19_-_60770628 3.33 ENSMUST00000238125.2
eukaryotic translation initiation factor 3, subunit A
chr1_+_40468720 3.31 ENSMUST00000174335.8
interleukin 1 receptor-like 1
chr3_+_89979948 3.29 ENSMUST00000121503.8
ENSMUST00000119570.8
tropomyosin 3, gamma
chr3_+_89043879 3.24 ENSMUST00000107482.10
ENSMUST00000127058.2
pyruvate kinase liver and red blood cell
chr3_+_89043440 3.21 ENSMUST00000047111.13
pyruvate kinase liver and red blood cell
chr1_+_45350698 3.05 ENSMUST00000087883.13
collagen, type III, alpha 1
chr11_-_86248395 2.95 ENSMUST00000043624.9
mediator complex subunit 13
chr16_-_63684477 2.84 ENSMUST00000232654.2
ENSMUST00000064405.8
Eph receptor A3
chr10_+_58207229 2.80 ENSMUST00000238939.2
LIM and senescent cell antigen-like domains 1
chr14_-_79718890 2.69 ENSMUST00000022601.7
WW domain binding protein 4
chr7_-_44541787 2.48 ENSMUST00000208551.2
ENSMUST00000208253.2
ENSMUST00000207654.2
ENSMUST00000207278.2
mediator complex subunit 25
chr1_+_75483721 2.48 ENSMUST00000037330.5
inhibin alpha
chr8_-_65489834 2.45 ENSMUST00000142822.4
apelin receptor early endogenous ligand
chr1_+_12762501 2.43 ENSMUST00000177608.8
ENSMUST00000180062.8
sulfatase 1
chr15_-_77037756 2.35 ENSMUST00000227314.2
ENSMUST00000227930.2
ENSMUST00000227533.2
RNA binding protein, fox-1 homolog (C. elegans) 2
chr7_-_44542098 2.34 ENSMUST00000003049.8
mediator complex subunit 25
chrX_-_104919201 2.33 ENSMUST00000198209.2
ATRX, chromatin remodeler
chr7_-_141241632 2.30 ENSMUST00000239500.1
mucin 6, gastric
chr4_-_132649798 2.29 ENSMUST00000097856.10
ENSMUST00000030696.11
family with sequence similarity 76, member A
chr5_+_24569802 2.29 ENSMUST00000115090.6
ENSMUST00000030834.7
nitric oxide synthase 3, endothelial cell
chr15_-_77037972 2.14 ENSMUST00000111581.4
ENSMUST00000166610.8
RNA binding protein, fox-1 homolog (C. elegans) 2
chr2_+_112097087 2.12 ENSMUST00000110987.9
ENSMUST00000028549.14
solute carrier family 12, member 6
chr5_-_122402451 2.11 ENSMUST00000111738.8
tectonic family member 1
chr14_-_54647647 2.07 ENSMUST00000228488.2
ENSMUST00000195970.5
solute carrier family 7 (cationic amino acid transporter, y+ system), member 7
chr11_-_53598078 1.76 ENSMUST00000124352.2
ENSMUST00000020649.14
RAD50 double strand break repair protein
chr2_+_112114906 1.72 ENSMUST00000053666.8
solute carrier family 12, member 6
chr5_-_35683035 1.70 ENSMUST00000038676.7
carboxypeptidase Z
chr8_+_85635189 1.64 ENSMUST00000003910.13
ENSMUST00000109744.8
deoxyribonuclease II alpha
chr8_-_65489791 1.60 ENSMUST00000124790.8
apelin receptor early endogenous ligand
chr19_-_37153436 1.58 ENSMUST00000142973.2
ENSMUST00000154376.8
cytoplasmic polyadenylation element binding protein 3
chr9_+_109881083 1.57 ENSMUST00000164930.8
ENSMUST00000199498.5
microtubule-associated protein 4
chr5_-_125371162 1.56 ENSMUST00000127148.2
scavenger receptor class B, member 1
chr8_+_85635341 1.48 ENSMUST00000134569.2
deoxyribonuclease II alpha
chr6_+_17306334 1.45 ENSMUST00000007799.13
ENSMUST00000115456.6
caveolin 1, caveolae protein
chr11_-_5848771 1.44 ENSMUST00000102921.4
myosin, light polypeptide 7, regulatory
chr9_-_32452885 1.42 ENSMUST00000016231.14
Friend leukemia integration 1
chr1_-_106980033 1.30 ENSMUST00000112717.3
serine (or cysteine) peptidase inhibitor, clade B (ovalbumin), member 3A
chr2_-_86109346 1.26 ENSMUST00000217294.2
ENSMUST00000217245.2
ENSMUST00000216432.2
olfactory receptor 1051
chr2_+_109522781 1.23 ENSMUST00000111050.10
brain derived neurotrophic factor
chr4_+_124696336 1.19 ENSMUST00000138807.8
ENSMUST00000030723.3
metal response element binding transcription factor 1
chr3_+_105811712 1.15 ENSMUST00000000574.3
adenosine A3 receptor
chr16_-_95260104 1.00 ENSMUST00000176345.10
ENSMUST00000121809.11
ENSMUST00000233664.2
ENSMUST00000122199.10
ETS transcription factor
chr18_+_76192529 0.95 ENSMUST00000167921.2
zinc finger and BTB domain containing 7C
chr10_-_13264574 0.92 ENSMUST00000079698.7
phosphatase and actin regulator 2
chr8_+_71047010 0.90 ENSMUST00000211117.2
myo-inositol 1-phosphate synthase A1
chr15_-_82796308 0.89 ENSMUST00000109510.10
ENSMUST00000048966.7
transcription factor 20
chr3_-_102690026 0.87 ENSMUST00000172026.8
ENSMUST00000170856.6
thyroid stimulating hormone, beta subunit
chr2_-_20973692 0.86 ENSMUST00000114594.8
Rho GTPase activating protein 21
chr17_-_84495364 0.80 ENSMUST00000060366.7
zinc finger protein 36, C3H type-like 2
chr18_+_57275854 0.77 ENSMUST00000139892.2
multiple EGF-like-domains 10
chr2_+_3705824 0.77 ENSMUST00000115054.9
family with sequence similarity 107, member B
chr8_-_40095706 0.76 ENSMUST00000210525.2
ENSMUST00000170091.3
macrophage scavenger receptor 1
chr16_-_63684425 0.75 ENSMUST00000232049.2
Eph receptor A3
chr1_+_172168764 0.72 ENSMUST00000056136.4
potassium inwardly-rectifying channel, subfamily J, member 10
chr8_+_71047263 0.72 ENSMUST00000211501.2
myo-inositol 1-phosphate synthase A1
chr8_+_85635311 0.69 ENSMUST00000145292.8
deoxyribonuclease II alpha
chr10_+_90412827 0.69 ENSMUST00000182550.8
ENSMUST00000099364.12
ankyrin repeat and sterile alpha motif domain containing 1B
chr8_+_11608412 0.60 ENSMUST00000209565.2
inhibitor of growth family, member 1
chr8_-_40095661 0.58 ENSMUST00000026021.14
macrophage scavenger receptor 1

Network of associatons between targets according to the STRING database.

First level regulatory network of Gata2_Gata1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
34.6 103.8 GO:0018160 peptidyl-pyrromethane cofactor linkage(GO:0018160)
28.9 86.8 GO:0002215 defense response to nematode(GO:0002215)
14.7 44.0 GO:0046462 monoacylglycerol metabolic process(GO:0046462)
14.6 58.5 GO:0072488 ammonium transmembrane transport(GO:0072488)
11.3 136.1 GO:0001955 blood vessel maturation(GO:0001955)
10.6 63.5 GO:0031133 regulation of axon diameter(GO:0031133)
9.7 77.6 GO:0006735 NADH regeneration(GO:0006735) canonical glycolysis(GO:0061621) glucose catabolic process to pyruvate(GO:0061718)
9.4 56.4 GO:0002528 regulation of vascular permeability involved in acute inflammatory response(GO:0002528)
9.3 175.8 GO:0043249 erythrocyte maturation(GO:0043249)
9.1 27.3 GO:0034378 chylomicron assembly(GO:0034378)
9.1 136.5 GO:0034242 negative regulation of syncytium formation by plasma membrane fusion(GO:0034242)
7.9 23.7 GO:0030221 basophil differentiation(GO:0030221)
7.3 73.0 GO:0033632 regulation of cell-cell adhesion mediated by integrin(GO:0033632)
6.9 34.5 GO:0060931 sinoatrial node cell development(GO:0060931)
6.5 52.1 GO:0002432 granuloma formation(GO:0002432)
6.2 37.3 GO:0071918 urea transmembrane transport(GO:0071918)
6.0 18.1 GO:0044240 multicellular organism lipid catabolic process(GO:0044240)
5.5 49.8 GO:1901164 negative regulation of trophoblast cell migration(GO:1901164)
5.5 38.5 GO:0002317 plasma cell differentiation(GO:0002317)
4.2 34.0 GO:0042699 follicle-stimulating hormone signaling pathway(GO:0042699)
4.2 59.4 GO:0061032 visceral serous pericardium development(GO:0061032)
3.5 48.8 GO:0097067 cellular response to thyroid hormone stimulus(GO:0097067)
3.3 83.4 GO:0046597 negative regulation of viral entry into host cell(GO:0046597)
3.3 13.3 GO:2000473 regulation of hematopoietic stem cell migration(GO:2000471) positive regulation of hematopoietic stem cell migration(GO:2000473)
2.9 8.8 GO:0006021 inositol biosynthetic process(GO:0006021)
2.8 8.5 GO:0002386 immune response in mucosal-associated lymphoid tissue(GO:0002386)
2.8 8.5 GO:1904116 response to vasopressin(GO:1904116) cellular response to vasopressin(GO:1904117)
2.6 21.1 GO:0002326 B cell lineage commitment(GO:0002326)
2.6 33.8 GO:0042541 hemoglobin biosynthetic process(GO:0042541)
2.6 7.7 GO:0070839 divalent metal ion export(GO:0070839)
2.6 12.8 GO:0046501 protoporphyrinogen IX metabolic process(GO:0046501)
2.4 17.1 GO:0060455 negative regulation of gastric acid secretion(GO:0060455)
2.3 43.3 GO:0016540 protein autoprocessing(GO:0016540)
1.9 7.4 GO:0051316 attachment of spindle microtubules to kinetochore involved in meiotic chromosome segregation(GO:0051316)
1.8 77.2 GO:1902175 regulation of oxidative stress-induced intrinsic apoptotic signaling pathway(GO:1902175)
1.8 19.6 GO:0030916 otic vesicle formation(GO:0030916)
1.8 84.3 GO:0032094 response to food(GO:0032094)
1.7 38.5 GO:0031000 response to caffeine(GO:0031000)
1.7 36.4 GO:0016075 rRNA catabolic process(GO:0016075)
1.7 62.0 GO:0051016 barbed-end actin filament capping(GO:0051016)
1.6 4.8 GO:2001176 mediator complex assembly(GO:0036034) regulation of mediator complex assembly(GO:2001176) positive regulation of mediator complex assembly(GO:2001178)
1.4 18.5 GO:0002002 regulation of angiotensin levels in blood(GO:0002002)
1.2 7.5 GO:0060298 positive regulation of sarcomere organization(GO:0060298)
1.2 3.6 GO:0097156 fasciculation of motor neuron axon(GO:0097156)
1.1 82.8 GO:0042982 amyloid precursor protein metabolic process(GO:0042982)
1.1 23.7 GO:0007379 segment specification(GO:0007379)
1.0 3.1 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)
1.0 3.8 GO:0071477 hypotonic salinity response(GO:0042539) cellular hypotonic salinity response(GO:0071477)
0.9 9.4 GO:0032264 purine nucleotide salvage(GO:0032261) IMP salvage(GO:0032264)
0.9 7.4 GO:0097646 calcitonin family receptor signaling pathway(GO:0097646) amylin receptor signaling pathway(GO:0097647)
0.9 27.1 GO:0048268 clathrin coat assembly(GO:0048268)
0.9 12.8 GO:0090527 actin filament reorganization(GO:0090527)
0.8 127.7 GO:0007586 digestion(GO:0007586)
0.8 3.4 GO:1902269 positive regulation of polyamine transmembrane transport(GO:1902269)
0.8 3.4 GO:1901675 negative regulation of histone H3-K27 acetylation(GO:1901675)
0.8 3.3 GO:0001732 formation of cytoplasmic translation initiation complex(GO:0001732)
0.8 5.6 GO:0030263 apoptotic chromosome condensation(GO:0030263)
0.8 2.3 GO:0014805 smooth muscle adaptation(GO:0014805)
0.7 11.8 GO:0021702 cerebellar Purkinje cell differentiation(GO:0021702)
0.7 64.1 GO:0070527 platelet aggregation(GO:0070527)
0.6 6.4 GO:0042866 pyruvate biosynthetic process(GO:0042866)
0.5 1.6 GO:1900248 cytoplasmic translational elongation(GO:0002182) regulation of cytoplasmic translational elongation(GO:1900247) negative regulation of cytoplasmic translational elongation(GO:1900248)
0.5 5.0 GO:0010724 regulation of definitive erythrocyte differentiation(GO:0010724)
0.5 2.9 GO:0014846 esophagus smooth muscle contraction(GO:0014846)
0.4 2.1 GO:1904491 protein localization to ciliary transition zone(GO:1904491)
0.4 7.8 GO:0038063 collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063)
0.4 1.2 GO:0061193 taste bud development(GO:0061193)
0.4 5.0 GO:0005981 regulation of glycogen catabolic process(GO:0005981)
0.4 34.1 GO:0006611 protein export from nucleus(GO:0006611)
0.4 0.7 GO:0051933 amino acid neurotransmitter reuptake(GO:0051933) glutamate reuptake(GO:0051935)
0.4 2.8 GO:2000346 negative regulation of hepatocyte proliferation(GO:2000346)
0.3 1.3 GO:0010885 regulation of cholesterol storage(GO:0010885) positive regulation of cholesterol storage(GO:0010886)
0.3 0.3 GO:0048807 female genitalia morphogenesis(GO:0048807) squamous basal epithelial stem cell differentiation involved in prostate gland acinus development(GO:0060529)
0.3 4.7 GO:1904261 regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904259) positive regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904261) basement membrane assembly involved in embryonic body morphogenesis(GO:2001197)
0.3 3.3 GO:0002826 negative regulation of T-helper 1 type immune response(GO:0002826)
0.3 40.4 GO:0045667 regulation of osteoblast differentiation(GO:0045667)
0.3 5.0 GO:0075522 IRES-dependent viral translational initiation(GO:0075522)
0.3 5.8 GO:0035855 megakaryocyte development(GO:0035855)
0.3 3.6 GO:0043517 positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517)
0.3 0.8 GO:0043654 recognition of apoptotic cell(GO:0043654)
0.3 1.5 GO:0035127 post-embryonic appendage morphogenesis(GO:0035120) post-embryonic limb morphogenesis(GO:0035127) post-embryonic forelimb morphogenesis(GO:0035128) telomeric repeat-containing RNA transcription(GO:0097393) telomeric repeat-containing RNA transcription from RNA pol II promoter(GO:0097394) regulation of telomeric RNA transcription from RNA pol II promoter(GO:1901580) negative regulation of telomeric RNA transcription from RNA pol II promoter(GO:1901581) positive regulation of telomeric RNA transcription from RNA pol II promoter(GO:1901582)
0.2 13.4 GO:0070098 chemokine-mediated signaling pathway(GO:0070098)
0.2 0.5 GO:0010700 negative regulation of norepinephrine secretion(GO:0010700)
0.2 1.6 GO:0051012 microtubule sliding(GO:0051012)
0.2 32.9 GO:0008203 cholesterol metabolic process(GO:0008203)
0.2 1.0 GO:0003199 endocardial cushion to mesenchymal transition involved in heart valve formation(GO:0003199)
0.2 8.6 GO:0030168 platelet activation(GO:0030168)
0.2 10.5 GO:0006730 one-carbon metabolic process(GO:0006730)
0.2 3.0 GO:2000291 regulation of myoblast proliferation(GO:2000291)
0.2 0.9 GO:0051684 maintenance of Golgi location(GO:0051684)
0.2 1.3 GO:0042270 protection from natural killer cell mediated cytotoxicity(GO:0042270)
0.2 2.9 GO:2000272 negative regulation of receptor activity(GO:2000272)
0.1 11.6 GO:0001541 ovarian follicle development(GO:0001541)
0.1 8.1 GO:0002181 cytoplasmic translation(GO:0002181)
0.1 1.1 GO:0002349 histamine production involved in inflammatory response(GO:0002349) histamine secretion involved in inflammatory response(GO:0002441) histamine secretion by mast cell(GO:0002553)
0.1 2.7 GO:0045292 mRNA cis splicing, via spliceosome(GO:0045292)
0.1 5.9 GO:0048873 homeostasis of number of cells within a tissue(GO:0048873)
0.1 16.1 GO:0007173 epidermal growth factor receptor signaling pathway(GO:0007173)
0.1 0.8 GO:1904627 response to phorbol 13-acetate 12-myristate(GO:1904627) cellular response to phorbol 13-acetate 12-myristate(GO:1904628)
0.1 0.5 GO:0038044 transforming growth factor-beta secretion(GO:0038044)
0.1 3.6 GO:0015804 neutral amino acid transport(GO:0015804)
0.1 4.4 GO:0038083 peptidyl-tyrosine autophosphorylation(GO:0038083)
0.1 8.2 GO:0010811 positive regulation of cell-substrate adhesion(GO:0010811)
0.1 0.3 GO:0060369 positive regulation of Fc receptor mediated stimulatory signaling pathway(GO:0060369)
0.1 0.4 GO:0000821 regulation of arginine metabolic process(GO:0000821)
0.1 21.1 GO:0006887 exocytosis(GO:0006887)
0.0 72.8 GO:0006508 proteolysis(GO:0006508)
0.0 3.8 GO:0030218 erythrocyte differentiation(GO:0030218)
0.0 3.6 GO:0009062 fatty acid catabolic process(GO:0009062)
0.0 0.5 GO:0071688 striated muscle myosin thick filament assembly(GO:0071688)
0.0 0.2 GO:0050882 voluntary musculoskeletal movement(GO:0050882)
0.0 0.3 GO:0021542 dentate gyrus development(GO:0021542)
0.0 0.0 GO:0009750 response to fructose(GO:0009750)
0.0 4.3 GO:0006260 DNA replication(GO:0006260)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
7.0 55.8 GO:0005833 hemoglobin complex(GO:0005833)
5.6 55.8 GO:0033093 Weibel-Palade body(GO:0033093)
4.1 62.0 GO:0008290 F-actin capping protein complex(GO:0008290)
2.5 7.4 GO:0000818 nuclear MIS12/MIND complex(GO:0000818)
1.8 77.6 GO:0097228 sperm principal piece(GO:0097228)
1.8 21.1 GO:0000788 nuclear nucleosome(GO:0000788)
1.6 33.0 GO:0031143 pseudopodium(GO:0031143)
1.2 70.0 GO:0002102 podosome(GO:0002102)
1.1 3.3 GO:0043614 multi-eIF complex(GO:0043614)
1.1 54.4 GO:0008305 integrin complex(GO:0008305)
0.8 2.5 GO:0034673 inhibin-betaglycan-ActRII complex(GO:0034673) inhibin A complex(GO:0043512)
0.7 128.4 GO:0032993 protein-DNA complex(GO:0032993)
0.6 7.8 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.6 120.0 GO:0030863 cortical cytoskeleton(GO:0030863)
0.6 5.5 GO:0072357 PTW/PP1 phosphatase complex(GO:0072357)
0.6 16.0 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.6 5.6 GO:0061574 ASAP complex(GO:0061574)
0.6 27.1 GO:0030131 clathrin adaptor complex(GO:0030131)
0.4 1.8 GO:0030870 Mre11 complex(GO:0030870)
0.4 23.7 GO:0008023 transcription elongation factor complex(GO:0008023)
0.4 105.3 GO:0000793 condensed chromosome(GO:0000793)
0.3 8.5 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.3 27.1 GO:0005643 nuclear pore(GO:0005643)
0.3 566.5 GO:0005615 extracellular space(GO:0005615)
0.2 62.6 GO:0009897 external side of plasma membrane(GO:0009897)
0.2 3.0 GO:0045180 basal cortex(GO:0045180)
0.2 12.3 GO:0005882 intermediate filament(GO:0005882)
0.2 17.1 GO:0030667 secretory granule membrane(GO:0030667)
0.2 3.4 GO:0016580 Sin3 complex(GO:0016580)
0.2 41.6 GO:0015629 actin cytoskeleton(GO:0015629)
0.1 0.7 GO:0097449 astrocyte projection(GO:0097449)
0.1 27.8 GO:0042383 sarcolemma(GO:0042383)
0.1 8.3 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.1 31.3 GO:0005759 mitochondrial matrix(GO:0005759)
0.1 48.9 GO:0005925 focal adhesion(GO:0005925)
0.1 1.6 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.1 0.8 GO:0001891 phagocytic cup(GO:0001891)
0.1 8.5 GO:0031225 anchored component of membrane(GO:0031225)
0.1 7.9 GO:0005769 early endosome(GO:0005769)
0.1 2.9 GO:0016592 mediator complex(GO:0016592)
0.1 10.0 GO:0031234 extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.1 53.3 GO:0031410 cytoplasmic vesicle(GO:0031410)
0.1 5.6 GO:0005884 actin filament(GO:0005884)
0.1 11.5 GO:0030427 site of polarized growth(GO:0030427)
0.1 132.2 GO:0070062 extracellular exosome(GO:0070062)
0.0 22.0 GO:0005887 integral component of plasma membrane(GO:0005887)
0.0 5.7 GO:0005874 microtubule(GO:0005874)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
34.6 103.8 GO:0004418 hydroxymethylbilane synthase activity(GO:0004418)
12.0 120.0 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
11.3 34.0 GO:0031896 V2 vasopressin receptor binding(GO:0031896)
10.8 53.9 GO:0070051 fibrinogen binding(GO:0070051)
10.4 31.3 GO:0003870 5-aminolevulinate synthase activity(GO:0003870) N-succinyltransferase activity(GO:0016749)
9.7 77.6 GO:0019158 fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
7.3 88.1 GO:0031545 peptidyl-proline 4-dioxygenase activity(GO:0031545)
7.3 44.0 GO:0003846 2-acylglycerol O-acyltransferase activity(GO:0003846)
6.3 56.4 GO:0004687 myosin light chain kinase activity(GO:0004687)
6.2 55.8 GO:0005344 oxygen transporter activity(GO:0005344)
5.7 39.9 GO:0015265 urea channel activity(GO:0015265)
5.5 49.8 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
5.3 165.5 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
4.4 17.4 GO:0004105 choline-phosphate cytidylyltransferase activity(GO:0004105)
2.9 8.8 GO:0004512 inositol-3-phosphate synthase activity(GO:0004512) intramolecular lyase activity(GO:0016872)
2.6 21.1 GO:0070644 vitamin D response element binding(GO:0070644)
2.3 134.1 GO:0050699 WW domain binding(GO:0050699)
2.1 27.1 GO:0005049 nuclear export signal receptor activity(GO:0005049)
2.0 18.1 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
1.9 58.5 GO:0008519 ammonium transmembrane transporter activity(GO:0008519)
1.7 367.0 GO:0004252 serine-type endopeptidase activity(GO:0004252)
1.4 43.3 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
1.3 23.7 GO:0008301 DNA binding, bending(GO:0008301)
1.3 6.4 GO:0004743 pyruvate kinase activity(GO:0004743)
1.2 17.1 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
1.2 8.5 GO:0008294 calcium- and calmodulin-responsive adenylate cyclase activity(GO:0008294)
1.1 3.4 GO:0099580 ion antiporter activity involved in regulation of postsynaptic membrane potential(GO:0099580)
1.1 12.4 GO:0031433 telethonin binding(GO:0031433)
1.1 3.4 GO:0042978 ornithine decarboxylase activator activity(GO:0042978)
1.1 3.3 GO:0002113 interleukin-33 binding(GO:0002113)
1.1 12.8 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
1.1 10.5 GO:0004064 arylesterase activity(GO:0004064)
1.0 3.8 GO:0035827 rubidium ion transmembrane transporter activity(GO:0035827)
1.0 13.4 GO:0019957 C-C chemokine binding(GO:0019957)
0.9 9.4 GO:0047623 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.8 3.8 GO:0004531 deoxyribonuclease II activity(GO:0004531)
0.7 34.5 GO:0030552 cAMP binding(GO:0030552)
0.7 60.4 GO:0030507 spectrin binding(GO:0030507)
0.6 14.5 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
0.6 107.8 GO:0005178 integrin binding(GO:0005178)
0.6 45.7 GO:0070888 E-box binding(GO:0070888)
0.6 7.8 GO:0038064 collagen receptor activity(GO:0038064)
0.6 2.3 GO:0034617 tetrahydrobiopterin binding(GO:0034617)
0.5 8.2 GO:0015093 ferrous iron transmembrane transporter activity(GO:0015093)
0.5 56.8 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.5 16.3 GO:0004190 aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.5 38.0 GO:0043022 ribosome binding(GO:0043022)
0.4 13.3 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
0.4 1.2 GO:0005169 neurotrophin TRKB receptor binding(GO:0005169)
0.4 2.9 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.4 29.4 GO:0001540 beta-amyloid binding(GO:0001540)
0.4 3.6 GO:0005004 GPI-linked ephrin receptor activity(GO:0005004)
0.4 5.0 GO:1990829 C-rich single-stranded DNA binding(GO:1990829)
0.3 43.3 GO:0004896 cytokine receptor activity(GO:0004896)
0.3 8.3 GO:0001968 fibronectin binding(GO:0001968)
0.3 2.5 GO:0034711 inhibin binding(GO:0034711)
0.3 0.8 GO:0001849 complement component C1q binding(GO:0001849)
0.3 4.1 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.2 56.0 GO:0017137 Rab GTPase binding(GO:0017137)
0.2 27.1 GO:0008565 protein transporter activity(GO:0008565)
0.2 1.5 GO:0015616 DNA translocase activity(GO:0015616)
0.2 4.3 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.2 61.0 GO:0030246 carbohydrate binding(GO:0030246)
0.2 1.8 GO:0051880 G-quadruplex DNA binding(GO:0051880)
0.2 3.6 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.1 10.0 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.1 68.4 GO:0008047 enzyme activator activity(GO:0008047)
0.1 8.1 GO:0019843 rRNA binding(GO:0019843)
0.1 0.8 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.1 2.7 GO:0070064 proline-rich region binding(GO:0070064)
0.1 0.5 GO:0004945 angiotensin type II receptor activity(GO:0004945)
0.1 0.7 GO:0015272 ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.1 13.8 GO:0047485 protein N-terminus binding(GO:0047485)
0.1 10.3 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.1 3.4 GO:0004407 histone deacetylase activity(GO:0004407)
0.1 3.6 GO:0015175 neutral amino acid transmembrane transporter activity(GO:0015175)
0.1 4.7 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.1 61.0 GO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding(GO:0000981)
0.1 3.3 GO:0003743 translation initiation factor activity(GO:0003743)
0.0 5.1 GO:0004860 protein kinase inhibitor activity(GO:0004860)
0.0 8.5 GO:0003823 antigen binding(GO:0003823)
0.0 7.0 GO:0017124 SH3 domain binding(GO:0017124)
0.0 33.6 GO:0008270 zinc ion binding(GO:0008270)
0.0 0.5 GO:0097493 structural molecule activity conferring elasticity(GO:0097493)
0.0 2.9 GO:0001104 RNA polymerase II transcription cofactor activity(GO:0001104)
0.0 0.9 GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding(GO:0000978)
0.0 0.4 GO:0015174 basic amino acid transmembrane transporter activity(GO:0015174)
0.0 0.6 GO:0035064 methylated histone binding(GO:0035064)
0.0 9.7 GO:0003682 chromatin binding(GO:0003682)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
2.1 74.3 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
1.9 86.8 NABA PROTEOGLYCANS Genes encoding proteoglycans
1.9 54.4 PID INTEGRIN CS PATHWAY Integrin family cell surface interactions
0.8 102.7 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network
0.7 34.0 PID IL8 CXCR1 PATHWAY IL8- and CXCR1-mediated signaling events
0.7 10.0 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.7 178.8 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.7 41.6 PID EPO PATHWAY EPO signaling pathway
0.6 62.0 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.6 37.7 PID PTP1B PATHWAY Signaling events mediated by PTP1B
0.6 21.1 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.5 49.8 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.4 8.5 PID LPA4 PATHWAY LPA4-mediated signaling events
0.4 25.1 PID FCER1 PATHWAY Fc-epsilon receptor I signaling in mast cells
0.3 13.3 PID BCR 5PATHWAY BCR signaling pathway
0.3 24.3 PID HDAC CLASSI PATHWAY Signaling events mediated by HDAC Class I
0.2 3.6 PID EPHA FWDPATHWAY EPHA forward signaling
0.2 2.3 PID VEGFR1 PATHWAY VEGFR1 specific signals
0.1 3.3 PID IL2 PI3K PATHWAY IL2 signaling events mediated by PI3K
0.1 4.1 PID TNF PATHWAY TNF receptor signaling pathway
0.1 8.4 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.1 11.9 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.1 3.1 PID ENDOTHELIN PATHWAY Endothelins
0.1 5.0 PID PLK1 PATHWAY PLK1 signaling events
0.1 6.4 ST INTEGRIN SIGNALING PATHWAY Integrin Signaling Pathway
0.1 2.8 PID ILK PATHWAY Integrin-linked kinase signaling
0.0 3.6 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors
0.0 1.2 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
6.2 147.9 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
3.0 93.5 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
2.8 62.6 REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS Genes involved in p130Cas linkage to MAPK signaling for integrins
1.8 27.1 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
1.4 34.0 REACTOME LYSOSOME VESICLE BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis
1.3 13.3 REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
1.3 77.7 REACTOME GLUCOSE TRANSPORT Genes involved in Glucose transport
1.2 16.0 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
1.2 68.5 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
1.0 18.1 REACTOME ACYL CHAIN REMODELLING OF PS Genes involved in Acyl chain remodelling of PS
0.9 33.8 REACTOME AMINE COMPOUND SLC TRANSPORTERS Genes involved in Amine compound SLC transporters
0.8 138.3 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.8 21.0 REACTOME SYNTHESIS OF PC Genes involved in Synthesis of PC
0.5 17.6 REACTOME ELONGATION ARREST AND RECOVERY Genes involved in Elongation arrest and recovery
0.5 8.5 REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB Genes involved in PKA-mediated phosphorylation of CREB
0.4 9.4 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.4 3.4 REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC Genes involved in Regulation of ornithine decarboxylase (ODC)
0.4 3.9 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.3 10.0 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
0.3 16.8 REACTOME MYOGENESIS Genes involved in Myogenesis
0.2 44.7 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.1 3.4 REACTOME PLATELET CALCIUM HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.1 7.7 REACTOME IRON UPTAKE AND TRANSPORT Genes involved in Iron uptake and transport
0.1 2.3 REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.1 5.0 REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
0.1 6.4 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.1 2.8 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.1 1.6 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.1 5.0 REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.1 7.4 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.1 11.4 REACTOME 3 UTR MEDIATED TRANSLATIONAL REGULATION Genes involved in 3' -UTR-mediated translational regulation
0.1 5.6 REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS Genes involved in Apoptotic cleavage of cellular proteins
0.0 5.5 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)