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GSE58827: Dynamics of the Mouse Liver

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Results for Gli1

Z-value: 0.66

Motif logo

Transcription factors associated with Gli1

Gene Symbol Gene ID Gene Info
ENSMUSG00000025407.8 GLI-Kruppel family member GLI1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Gli1mm39_v1_chr10_-_127177729_1271778430.372.5e-02Click!

Activity profile of Gli1 motif

Sorted Z-values of Gli1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr11_-_102255999 4.55 ENSMUST00000006749.10
solute carrier family 4 (anion exchanger), member 1
chr7_+_24069680 4.10 ENSMUST00000205428.2
ENSMUST00000171904.3
ENSMUST00000205626.2
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 4
chr10_+_79722081 3.89 ENSMUST00000046091.7
elastase, neutrophil expressed
chr11_+_115790768 3.39 ENSMUST00000152171.8
small integral membrane protein 5
chr6_+_30738043 2.90 ENSMUST00000163949.9
ENSMUST00000124665.3
mesoderm specific transcript
chr2_+_157401998 2.88 ENSMUST00000153739.9
ENSMUST00000173595.2
ENSMUST00000109526.2
ENSMUST00000173839.2
ENSMUST00000173041.8
ENSMUST00000173793.8
ENSMUST00000172487.2
ENSMUST00000088484.6
neuronatin
chr9_+_106083988 2.80 ENSMUST00000188650.2
twinfilin actin binding protein 2
chr7_-_24459736 2.63 ENSMUST00000063956.7
CD177 antigen
chr11_+_72889889 2.56 ENSMUST00000021141.14
purinergic receptor P2X, ligand-gated ion channel, 1
chr5_-_110987604 2.49 ENSMUST00000056937.12
HscB iron-sulfur cluster co-chaperone
chr2_-_152672535 2.45 ENSMUST00000146380.2
ENSMUST00000134902.2
ENSMUST00000134357.2
ENSMUST00000109820.5
BCL2-like 1
chr4_-_133601990 2.38 ENSMUST00000168974.9
ribosomal protein S6 kinase polypeptide 1
chr2_+_117942357 2.22 ENSMUST00000039559.9
thrombospondin 1
chr1_-_133728779 2.12 ENSMUST00000143567.8
ATPase, Ca++ transporting, plasma membrane 4
chr6_+_113508636 1.93 ENSMUST00000036340.12
ENSMUST00000204827.3
Fanconi anemia, complementation group D2
chr5_-_110987441 1.87 ENSMUST00000145318.2
HscB iron-sulfur cluster co-chaperone
chr2_+_29779750 1.87 ENSMUST00000113763.8
ENSMUST00000113757.8
ENSMUST00000113756.8
ENSMUST00000133233.8
ENSMUST00000113759.9
ENSMUST00000113755.8
ENSMUST00000137558.8
ENSMUST00000046571.14
outer dense fiber of sperm tails 2
chr5_-_115438971 1.85 ENSMUST00000112090.2
dynein light chain LC8-type 1
chr18_-_35795233 1.84 ENSMUST00000025209.12
ENSMUST00000096573.4
spermatogenesis associated 24
chr13_+_6598185 1.82 ENSMUST00000021611.10
ENSMUST00000222485.2
pitrilysin metallepetidase 1
chr15_-_103218876 1.80 ENSMUST00000079824.6
G protein-coupled receptor 84
chr5_-_115439016 1.78 ENSMUST00000009157.4
dynein light chain LC8-type 1
chr6_-_122587005 1.64 ENSMUST00000032211.5
growth differentiation factor 3
chr3_+_95836558 1.63 ENSMUST00000165307.8
ENSMUST00000015893.13
ENSMUST00000169426.8
acidic (leucine-rich) nuclear phosphoprotein 32 family, member E
chr4_+_154954042 1.52 ENSMUST00000079269.14
ENSMUST00000163732.8
ENSMUST00000080559.13
membrane metallo-endopeptidase-like 1
chr3_+_95836637 1.50 ENSMUST00000171368.8
ENSMUST00000168106.8
acidic (leucine-rich) nuclear phosphoprotein 32 family, member E
chr7_+_28682253 1.43 ENSMUST00000085835.8
mitogen-activated protein kinase kinase kinase kinase 1
chr2_-_152673032 1.42 ENSMUST00000128172.3
BCL2-like 1
chr18_-_35795175 1.36 ENSMUST00000236574.2
ENSMUST00000236971.2
spermatogenesis associated 24
chr2_+_29780122 1.34 ENSMUST00000113762.8
ENSMUST00000113765.8
outer dense fiber of sperm tails 2
chr17_+_34824827 1.27 ENSMUST00000037489.15
1-acylglycerol-3-phosphate O-acyltransferase 1 (lysophosphatidic acid acyltransferase, alpha)
chr15_-_100567377 1.24 ENSMUST00000182814.8
ENSMUST00000238935.2
ENSMUST00000182068.8
ENSMUST00000182574.2
ENSMUST00000182775.8
bridging integrator 2
chrX_+_139857640 1.16 ENSMUST00000112971.2
autophagy related 4A, cysteine peptidase
chrX_+_158086253 1.14 ENSMUST00000112491.2
ribosomal protein S6 kinase polypeptide 3
chrX_+_139857688 1.14 ENSMUST00000239541.1
autophagy related 4A, cysteine peptidase
chr19_-_46321218 1.08 ENSMUST00000238062.2
CUE domain containing 2
chr17_-_24428351 1.07 ENSMUST00000024931.6
netrin 3
chr9_-_106762818 1.04 ENSMUST00000185707.2
RNA binding motif protein 15B
chr6_-_124410452 1.04 ENSMUST00000124998.2
ENSMUST00000238807.2
calsyntenin 3
chr6_-_67014348 1.00 ENSMUST00000204369.2
growth arrest and DNA-damage-inducible 45 alpha
chr4_-_45320579 0.99 ENSMUST00000030003.10
exosome component 3
chr12_-_103304573 0.94 ENSMUST00000149431.2
ankyrin repeat and SOCS box-containing 2
chr6_-_67014191 0.91 ENSMUST00000204282.2
growth arrest and DNA-damage-inducible 45 alpha
chr6_+_28423539 0.91 ENSMUST00000020717.12
ENSMUST00000169841.2
ADP-ribosylation factor 5
chr15_-_51855073 0.90 ENSMUST00000022927.11
RAD21 cohesin complex component
chr4_-_41275091 0.85 ENSMUST00000030143.13
ENSMUST00000108068.8
ubiquitin-associated protein 2
chr2_+_29780532 0.84 ENSMUST00000113764.4
outer dense fiber of sperm tails 2
chr11_+_3239868 0.83 ENSMUST00000094471.10
ENSMUST00000110043.8
POZ (BTB) and AT hook containing zinc finger 1
chr3_-_94566107 0.81 ENSMUST00000196655.5
ENSMUST00000200407.2
ENSMUST00000006123.11
ENSMUST00000196733.5
tuftelin 1
chr17_-_90217868 0.76 ENSMUST00000086423.6
predicted pseudogene 10184
chr11_-_34724458 0.74 ENSMUST00000093191.3
spindle apparatus coiled-coil protein 1
chr11_+_76900091 0.73 ENSMUST00000129572.3
solute carrier family 6 (neurotransmitter transporter, serotonin), member 4
chr13_-_63579497 0.73 ENSMUST00000160931.2
ENSMUST00000099444.10
ENSMUST00000220684.2
ENSMUST00000161977.8
ENSMUST00000163091.8
Fanconi anemia, complementation group C
chr14_-_54646917 0.73 ENSMUST00000000984.9
solute carrier family 7 (cationic amino acid transporter, y+ system), member 7
chr4_+_118285275 0.72 ENSMUST00000006557.13
ENSMUST00000167636.8
ENSMUST00000102673.11
elongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like 1
chrX_+_154045439 0.72 ENSMUST00000026324.10
acyl-CoA thioesterase 9
chr11_-_83353787 0.71 ENSMUST00000021020.13
ENSMUST00000119346.2
ENSMUST00000103209.10
ENSMUST00000108137.9
matrix metallopeptidase 28 (epilysin)
chr2_+_29780073 0.70 ENSMUST00000028128.13
outer dense fiber of sperm tails 2
chr5_-_110927803 0.70 ENSMUST00000112426.8
pseudouridine synthase 1
chr11_-_41891111 0.69 ENSMUST00000109290.2
gamma-aminobutyric acid (GABA) A receptor, subunit gamma 2
chr2_+_84867554 0.69 ENSMUST00000077798.13
structure specific recognition protein 1
chr11_-_76289888 0.68 ENSMUST00000021204.4
nucleoredoxin
chr7_-_19504446 0.67 ENSMUST00000003061.14
basal cell adhesion molecule
chr16_-_90807983 0.63 ENSMUST00000170853.8
ENSMUST00000130813.3
ENSMUST00000118390.10
synaptojanin 1
chr2_-_91762033 0.63 ENSMUST00000111309.8
ENSMUST00000090602.6
midkine
chr7_+_79836581 0.63 ENSMUST00000032754.9
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B
chr13_+_81931196 0.60 ENSMUST00000022009.10
ENSMUST00000223793.2
centrin 3
chr2_-_91762119 0.59 ENSMUST00000069423.13
midkine
chr11_-_45846291 0.58 ENSMUST00000011398.13
tRNA-histidine guanylyltransferase 1-like (S. cerevisiae)
chr7_+_127845984 0.57 ENSMUST00000164710.8
ENSMUST00000070656.12
transforming growth factor beta 1 induced transcript 1
chr7_+_127846121 0.57 ENSMUST00000167965.8
transforming growth factor beta 1 induced transcript 1
chr10_+_79613083 0.56 ENSMUST00000020575.5
follistatin-like 3
chr2_+_152950388 0.54 ENSMUST00000189688.2
ENSMUST00000109799.8
ENSMUST00000003370.14
hemopoietic cell kinase
chr19_-_6593049 0.54 ENSMUST00000113451.9
solute carrier family 22 (organic anion/cation transporter), member 12
chrX_-_139857424 0.52 ENSMUST00000033805.15
ENSMUST00000112978.2
proteasome (prosome, macropain) 26S subunit, non-ATPase, 10
chr4_-_117539431 0.52 ENSMUST00000102687.4
DNA methyltransferase 1-associated protein 1
chr6_-_148846247 0.48 ENSMUST00000111562.8
ENSMUST00000081956.12
SIN3-HDAC complex associated factor
chr5_-_123038329 0.47 ENSMUST00000031435.14
lysine (K)-specific demethylase 2B
chr3_+_138058139 0.46 ENSMUST00000090166.5
alcohol dehydrogenase 6B (class V)
chrX_-_58613428 0.45 ENSMUST00000119833.8
ENSMUST00000131319.8
fibroblast growth factor 13
chr5_-_123127346 0.45 ENSMUST00000118027.8
lysine (K)-specific demethylase 2B
chr1_+_133278248 0.45 ENSMUST00000094556.3
renin 1 structural
chr2_+_84867783 0.44 ENSMUST00000168266.8
ENSMUST00000130729.3
structure specific recognition protein 1
chr7_-_110673269 0.43 ENSMUST00000163014.2
eukaryotic translation initiation factor 4, gamma 2
chr17_+_17669082 0.43 ENSMUST00000140134.2
limb and CNS expressed 1
chr12_-_69243871 0.42 ENSMUST00000223192.2
predicted gene, 49383
chr11_-_45845992 0.41 ENSMUST00000109254.2
tRNA-histidine guanylyltransferase 1-like (S. cerevisiae)
chr8_+_121854566 0.41 ENSMUST00000181609.2
forkhead box L1
chr2_+_106523532 0.41 ENSMUST00000111063.8
metallophosphoesterase domain containing 2
chr3_-_92393193 0.41 ENSMUST00000054599.8
small proline-rich protein 1A
chr9_+_118335294 0.39 ENSMUST00000084820.6
golgi autoantigen, golgin subfamily a, 4
chr7_+_127084283 0.39 ENSMUST00000048896.8
fibrosin
chr5_-_123859070 0.39 ENSMUST00000031376.12
zinc finger, CCHC domain containing 8
chr8_+_85763534 0.39 ENSMUST00000093360.12
transportin 2 (importin 3, karyopherin beta 2b)
chr7_+_27198740 0.37 ENSMUST00000098644.9
ENSMUST00000108355.2
ENSMUST00000238936.2
periaxin
chr5_-_123859153 0.36 ENSMUST00000196282.5
zinc finger, CCHC domain containing 8
chrX_-_166165743 0.35 ENSMUST00000026839.5
phosphoribosyl pyrophosphate synthetase 2
chr15_-_56557920 0.35 ENSMUST00000050544.8
hyaluronan synthase 2
chr10_-_63257568 0.35 ENSMUST00000054760.6
predicted gene 7075
chr2_+_118865262 0.35 ENSMUST00000028796.2
RNA pseudouridylate synthase domain containing 2
chr11_-_78136767 0.34 ENSMUST00000002121.5
SPT6, histone chaperone and transcription elongation factor
chr4_-_40948196 0.34 ENSMUST00000030125.5
ENSMUST00000108089.8
ENSMUST00000191273.7
BCL2-associated athanogene 1
chr7_+_127865472 0.34 ENSMUST00000033045.11
solute carrier family 5 (sodium/glucose cotransporter), member 2
chr15_-_85466009 0.33 ENSMUST00000023015.15
wingless-type MMTV integration site family, member 7B
chr9_+_110134241 0.33 ENSMUST00000199592.5
ENSMUST00000068071.12
elongator acetyltransferase complex subunit 6
chr10_+_22520910 0.33 ENSMUST00000042261.5
solute carrier family 2 (facilitated glucose transporter), member 12
chr2_+_181139016 0.33 ENSMUST00000108799.10
tumor protein D52-like 2
chr13_+_109822527 0.32 ENSMUST00000074103.12
phosphodiesterase 4D, cAMP specific
chr4_-_82939330 0.32 ENSMUST00000071708.12
Fras1 related extracellular matrix protein 1
chr7_+_140796537 0.32 ENSMUST00000141804.2
Ras association (RalGDS/AF-6) domain family (N-terminal) member 7
chr2_-_151815759 0.31 ENSMUST00000109865.8
ENSMUST00000109864.8
family with sequence similarity 110, member A
chr19_+_11382092 0.30 ENSMUST00000153546.8
membrane-spanning 4-domains, subfamily A, member 4C
chr2_+_181138958 0.30 ENSMUST00000149163.8
ENSMUST00000000844.15
ENSMUST00000184849.8
ENSMUST00000108800.8
ENSMUST00000069712.9
tumor protein D52-like 2
chr11_-_41891359 0.28 ENSMUST00000070735.10
gamma-aminobutyric acid (GABA) A receptor, subunit gamma 2
chr12_+_17778198 0.28 ENSMUST00000222944.2
hippocalcin-like 1
chr11_+_101066867 0.27 ENSMUST00000103109.4
contactin associated protein-like 1
chr2_+_76200299 0.27 ENSMUST00000046389.5
RNA binding motif protein 45
chr13_+_81931642 0.27 ENSMUST00000224574.2
centrin 3
chr11_+_62737936 0.27 ENSMUST00000150989.8
ENSMUST00000176577.2
F-box and WD-40 domain protein 10
chr11_+_78136569 0.26 ENSMUST00000002133.9
stromal cell derived factor 2
chr8_-_33374825 0.26 ENSMUST00000238791.2
neuregulin 1
chr6_-_41613322 0.26 ENSMUST00000031902.7
transient receptor potential cation channel, subfamily V, member 6
chr10_+_80084955 0.25 ENSMUST00000105364.8
NADH:ubiquinone oxidoreductase core subunit S7
chr18_-_70274639 0.25 ENSMUST00000121693.8
RAB27B, member RAS oncogene family
chr11_+_62737887 0.25 ENSMUST00000036085.11
F-box and WD-40 domain protein 10
chr1_-_125839897 0.25 ENSMUST00000159417.2
Ly6/Plaur domain containing 1
chr13_+_44882998 0.25 ENSMUST00000174068.8
jumonji, AT rich interactive domain 2
chr7_-_137999434 0.24 ENSMUST00000160436.2
transcription elongation regulator 1-like
chr8_+_70953766 0.24 ENSMUST00000127983.2
cytokine receptor-like factor 1
chrX_-_58612709 0.23 ENSMUST00000124402.2
fibroblast growth factor 13
chr3_+_90511068 0.22 ENSMUST00000001046.7
S100 calcium binding protein A4
chr4_+_114678919 0.22 ENSMUST00000137570.2
predicted gene 12830
chr8_-_106692668 0.21 ENSMUST00000116429.9
ENSMUST00000034370.17
solute carrier family 12, member 4
chr6_-_52195663 0.21 ENSMUST00000134367.4
homeobox A7
chr8_-_33374282 0.21 ENSMUST00000209107.4
ENSMUST00000209022.3
neuregulin 1
chr13_-_114595475 0.21 ENSMUST00000022287.8
ENSMUST00000223640.3
follistatin
chr10_+_69369590 0.20 ENSMUST00000182884.8
ankyrin 3, epithelial
chr1_+_129201081 0.20 ENSMUST00000073527.13
ENSMUST00000040311.14
thrombospondin, type I, domain containing 7B
chr12_-_114117264 0.20 ENSMUST00000103461.5
immunoglobulin heavy variable 7-3
chr3_+_88049875 0.20 ENSMUST00000107558.9
ENSMUST00000107559.3
myocyte enhancer factor 2D
chr10_+_69369854 0.20 ENSMUST00000182557.8
ankyrin 3, epithelial
chr2_+_121287444 0.20 ENSMUST00000126764.2
huntingtin interacting protein K
chr12_-_113561594 0.20 ENSMUST00000103444.3
immunoglobulin heavy variable 5-4
chr2_-_59778560 0.19 ENSMUST00000153136.2
bromodomain adjacent to zinc finger domain, 2B
chr5_-_136275407 0.19 ENSMUST00000196245.2
SH2B adaptor protein 2
chr11_+_80191692 0.19 ENSMUST00000017836.8
rhomboid like 3
chr10_-_63926044 0.19 ENSMUST00000105439.2
leucine rich repeat transmembrane neuronal 3
chr7_-_66915756 0.19 ENSMUST00000207715.2
myocyte enhancer factor 2A
chr14_-_54647647 0.19 ENSMUST00000228488.2
ENSMUST00000195970.5
solute carrier family 7 (cationic amino acid transporter, y+ system), member 7
chr12_-_70158348 0.18 ENSMUST00000220689.2
ninein
chr9_-_96774719 0.18 ENSMUST00000154146.8
2-phosphoxylose phosphatase 1
chr6_-_52222776 0.17 ENSMUST00000048026.10
homeobox A11
chr2_+_154855451 0.17 ENSMUST00000029123.3
nonagouti
chr7_-_3918484 0.17 ENSMUST00000038176.15
ENSMUST00000206077.2
ENSMUST00000090689.5
leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 6
chr2_+_26220403 0.17 ENSMUST00000114134.9
ENSMUST00000127453.2
G-protein signalling modulator 1 (AGS3-like, C. elegans)
chr13_-_63579551 0.16 ENSMUST00000073029.13
Fanconi anemia, complementation group C
chr9_+_113570506 0.16 ENSMUST00000213663.2
CLIP associating protein 2
chr10_+_69369632 0.16 ENSMUST00000182155.8
ENSMUST00000183169.8
ENSMUST00000183148.8
ankyrin 3, epithelial
chr12_-_113823290 0.16 ENSMUST00000103459.5
immunoglobulin heavy variable 5-17
chr5_+_5623799 0.16 ENSMUST00000101627.5
predicted gene 8773
chr10_+_69370038 0.15 ENSMUST00000182439.8
ENSMUST00000092434.12
ENSMUST00000047061.13
ENSMUST00000092432.12
ENSMUST00000092431.12
ENSMUST00000054167.15
ankyrin 3, epithelial
chr3_+_88049633 0.15 ENSMUST00000001455.13
ENSMUST00000119251.8
myocyte enhancer factor 2D
chr9_-_107482494 0.14 ENSMUST00000102529.10
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B
chr6_+_48603698 0.14 ENSMUST00000095938.10
expressed sequence AI854703
chr9_-_107482462 0.14 ENSMUST00000194433.6
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B
chr7_+_134870237 0.14 ENSMUST00000210697.2
ENSMUST00000097983.5
neuropeptide S
chr6_-_51989456 0.13 ENSMUST00000078214.8
ENSMUST00000204778.3
src family associated phosphoprotein 2
chrX_+_100342749 0.13 ENSMUST00000118111.8
ENSMUST00000130555.8
ENSMUST00000151528.8
neuroligin 3
chr18_+_37610858 0.13 ENSMUST00000051442.7
protocadherin beta 16
chr11_-_58692770 0.13 ENSMUST00000094156.12
ENSMUST00000239007.2
ENSMUST00000238886.2
ENSMUST00000060581.5
family with sequence similarity 183, member B
chr3_+_92195873 0.13 ENSMUST00000090872.7
small proline-rich protein 2A3
chr14_-_40730180 0.12 ENSMUST00000136661.8
peroxiredoxin like 2A
chr10_+_80085275 0.12 ENSMUST00000020361.7
NADH:ubiquinone oxidoreductase core subunit S7
chr5_+_91222470 0.12 ENSMUST00000031324.6
epiregulin
chr17_-_57338468 0.12 ENSMUST00000007814.10
ENSMUST00000233480.2
KH-type splicing regulatory protein
chr13_+_54722823 0.11 ENSMUST00000026988.11
ADP-ribosylation factor-like 10
chr18_+_61820982 0.10 ENSMUST00000025471.4
interleukin 17B
chr11_-_69435382 0.10 ENSMUST00000035539.12
dynein, axonemal, heavy chain 2
chr7_-_142453722 0.10 ENSMUST00000000219.10
tyrosine hydroxylase
chr9_+_113570580 0.10 ENSMUST00000216817.2
CLIP associating protein 2
chr10_-_98962187 0.09 ENSMUST00000060761.7
per-hexamer repeat gene 2
chr12_-_113625906 0.09 ENSMUST00000103448.3
immunoglobulin heavy variable 5-9
chr2_+_164721277 0.08 ENSMUST00000041643.5
phosphorylated CTD interacting factor 1
chr7_-_6334239 0.08 ENSMUST00000127658.2
ENSMUST00000062765.14
zinc finger protein 583
chr16_-_4376471 0.08 ENSMUST00000230875.2
transcription factor AP4
chr16_-_19703014 0.08 ENSMUST00000100083.5
ENSMUST00000231564.2
RIKEN cDNA A930003A15 gene
chr13_+_54722833 0.08 ENSMUST00000156024.2
ADP-ribosylation factor-like 10
chr13_-_114595122 0.08 ENSMUST00000231252.2
follistatin
chr15_-_101848689 0.08 ENSMUST00000023799.8
keratin 79
chr9_-_50663571 0.08 ENSMUST00000042790.5
heat shock protein 2
chr9_+_107805647 0.08 ENSMUST00000085073.2
actin-like 11
chr2_-_89623963 0.07 ENSMUST00000216587.2
ENSMUST00000111523.3
olfactory receptor 1254
chr17_-_46044768 0.07 ENSMUST00000178179.2
RIKEN cDNA 1600014C23 gene
chrX_+_118836893 0.07 ENSMUST00000040961.3
ENSMUST00000113366.2
poly(A) binding protein, cytoplasmic 5
chr4_+_127881786 0.07 ENSMUST00000184063.3
CUB and Sushi multiple domains 2
chr5_-_123185073 0.07 ENSMUST00000031437.14
MORN repeat containing 3
chr12_-_113945961 0.05 ENSMUST00000103466.2
immunoglobulin heavy variable 11-1
chr12_+_44375665 0.05 ENSMUST00000110748.4
neuronal cell adhesion molecule
chr16_+_92295009 0.05 ENSMUST00000023670.4
chloride intracellular channel 6
chr1_-_25267894 0.05 ENSMUST00000126626.8
adhesion G protein-coupled receptor B3

Network of associatons between targets according to the STRING database.

First level regulatory network of Gli1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 3.9 GO:0002777 antimicrobial peptide biosynthetic process(GO:0002777) antibacterial peptide biosynthetic process(GO:0002780) neutrophil mediated killing of fungus(GO:0070947)
1.1 4.3 GO:0010751 negative regulation of nitric oxide mediated signal transduction(GO:0010751)
1.0 3.9 GO:0046898 response to cycloheximide(GO:0046898)
0.5 4.4 GO:0097428 protein maturation by iron-sulfur cluster transfer(GO:0097428)
0.4 2.6 GO:0002554 serotonin secretion by platelet(GO:0002554)
0.3 3.6 GO:2000580 regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)
0.3 2.3 GO:0051697 protein delipidation(GO:0051697)
0.3 2.8 GO:0032532 regulation of microvillus length(GO:0032532)
0.3 2.4 GO:2000491 positive regulation of hepatic stellate cell activation(GO:2000491)
0.3 4.1 GO:0050862 positive regulation of T cell receptor signaling pathway(GO:0050862)
0.2 1.0 GO:0071043 CUT catabolic process(GO:0071034) CUT metabolic process(GO:0071043)
0.2 0.9 GO:0021993 initiation of neural tube closure(GO:0021993)
0.2 0.6 GO:0098884 postsynaptic neurotransmitter receptor internalization(GO:0098884)
0.2 1.2 GO:0030421 defecation(GO:0030421)
0.2 1.9 GO:2000348 regulation of CD40 signaling pathway(GO:2000348)
0.2 0.7 GO:0014064 positive regulation of serotonin secretion(GO:0014064) negative regulation of cerebellar granule cell precursor proliferation(GO:0021941)
0.2 1.6 GO:0048859 formation of anatomical boundary(GO:0048859)
0.2 0.5 GO:0070682 proteasome regulatory particle assembly(GO:0070682)
0.2 4.5 GO:0015701 bicarbonate transport(GO:0015701)
0.2 0.9 GO:0000821 regulation of arginine metabolic process(GO:0000821)
0.1 0.7 GO:0010760 negative regulation of macrophage chemotaxis(GO:0010760)
0.1 1.9 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.1 1.1 GO:0010936 negative regulation of macrophage cytokine production(GO:0010936)
0.1 3.1 GO:0043486 histone exchange(GO:0043486)
0.1 0.4 GO:0045226 extracellular polysaccharide biosynthetic process(GO:0045226) extracellular polysaccharide metabolic process(GO:0046379)
0.1 0.7 GO:1990481 mRNA pseudouridine synthesis(GO:1990481)
0.1 1.1 GO:0030579 ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.1 0.4 GO:0061146 Peyer's patch morphogenesis(GO:0061146)
0.1 0.7 GO:0045200 establishment or maintenance of neuroblast polarity(GO:0045196) establishment of neuroblast polarity(GO:0045200)
0.1 1.2 GO:1902474 positive regulation of protein localization to synapse(GO:1902474)
0.1 0.4 GO:0046391 5-phosphoribose 1-diphosphate biosynthetic process(GO:0006015) 5-phosphoribose 1-diphosphate metabolic process(GO:0046391)
0.1 0.3 GO:0016332 establishment or maintenance of polarity of embryonic epithelium(GO:0016332)
0.1 0.9 GO:0045876 positive regulation of sister chromatid cohesion(GO:0045876)
0.1 1.3 GO:0006654 phosphatidic acid biosynthetic process(GO:0006654)
0.1 0.4 GO:0002018 renin-angiotensin regulation of aldosterone production(GO:0002018)
0.1 0.3 GO:0061086 negative regulation of histone H3-K27 methylation(GO:0061086)
0.1 0.4 GO:0032290 peripheral nervous system myelin formation(GO:0032290)
0.1 0.7 GO:0034625 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.1 0.6 GO:2000672 negative regulation of motor neuron apoptotic process(GO:2000672)
0.1 0.7 GO:1900827 positive regulation of cell communication by electrical coupling(GO:0010650) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.1 0.2 GO:0040030 regulation of molecular function, epigenetic(GO:0040030)
0.1 4.7 GO:1902017 regulation of cilium assembly(GO:1902017)
0.1 0.8 GO:0032926 negative regulation of activin receptor signaling pathway(GO:0032926)
0.1 0.5 GO:0021842 directional guidance of interneurons involved in migration from the subpallium to the cortex(GO:0021840) chemorepulsion involved in interneuron migration from the subpallium to the cortex(GO:0021842)
0.0 0.1 GO:0010841 positive regulation of circadian sleep/wake cycle, wakefulness(GO:0010841)
0.0 0.2 GO:0090222 centrosome-templated microtubule nucleation(GO:0090222)
0.0 0.7 GO:0034501 protein localization to kinetochore(GO:0034501)
0.0 0.3 GO:0031118 rRNA pseudouridine synthesis(GO:0031118)
0.0 2.9 GO:0010883 regulation of lipid storage(GO:0010883)
0.0 1.2 GO:0097320 membrane tubulation(GO:0097320)
0.0 0.2 GO:0055005 ventricular cardiac myofibril assembly(GO:0055005)
0.0 0.2 GO:0010908 regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010908) positive regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010909)
0.0 0.5 GO:0015747 urate transport(GO:0015747)
0.0 0.9 GO:0097150 neuronal stem cell population maintenance(GO:0097150)
0.0 0.4 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.0 0.7 GO:0035428 hexose transmembrane transport(GO:0035428)
0.0 0.4 GO:0019227 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.0 0.2 GO:0001922 B-1 B cell homeostasis(GO:0001922)
0.0 0.3 GO:1903690 negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
0.0 0.3 GO:1901898 negative regulation of relaxation of cardiac muscle(GO:1901898)
0.0 0.6 GO:0071420 cellular response to histamine(GO:0071420)
0.0 0.1 GO:0048165 ovarian cumulus expansion(GO:0001550) fused antrum stage(GO:0048165)
0.0 0.1 GO:0042414 epinephrine metabolic process(GO:0042414)
0.0 0.2 GO:0045617 negative regulation of keratinocyte differentiation(GO:0045617)
0.0 0.9 GO:0006890 retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)
0.0 2.0 GO:0032024 positive regulation of insulin secretion(GO:0032024)
0.0 0.5 GO:0043968 histone H2A acetylation(GO:0043968)
0.0 0.9 GO:0050919 negative chemotaxis(GO:0050919)
0.0 0.2 GO:0051574 positive regulation of histone H3-K9 methylation(GO:0051574)
0.0 0.5 GO:0071801 regulation of podosome assembly(GO:0071801) positive regulation of actin cytoskeleton reorganization(GO:2000251)
0.0 0.0 GO:0036275 response to 5-fluorouracil(GO:0036275)
0.0 1.1 GO:0007520 myoblast fusion(GO:0007520)
0.0 0.3 GO:0035898 parathyroid hormone secretion(GO:0035898)
0.0 0.3 GO:0071712 ER-associated misfolded protein catabolic process(GO:0071712)
0.0 1.0 GO:0006400 tRNA modification(GO:0006400)
0.0 1.0 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.0 0.1 GO:2000628 regulation of miRNA metabolic process(GO:2000628)
0.0 0.2 GO:0060272 embryonic skeletal joint morphogenesis(GO:0060272)
0.0 0.3 GO:0097094 craniofacial suture morphogenesis(GO:0097094)
0.0 0.3 GO:0032402 melanosome transport(GO:0032402)
0.0 0.5 GO:0018149 peptide cross-linking(GO:0018149)
0.0 0.8 GO:0045773 positive regulation of axon extension(GO:0045773)
0.0 0.4 GO:0097352 autophagosome maturation(GO:0097352)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 2.6 GO:0030312 external encapsulating structure(GO:0030312)
0.3 3.9 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.3 4.9 GO:0097539 ciliary transition fiber(GO:0097539)
0.2 2.2 GO:0005577 fibrinogen complex(GO:0005577)
0.2 3.6 GO:1904115 axon cytoplasm(GO:1904115)
0.1 0.9 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
0.1 0.9 GO:0000798 nuclear cohesin complex(GO:0000798)
0.1 0.4 GO:0002189 ribose phosphate diphosphokinase complex(GO:0002189)
0.1 0.3 GO:1903754 cortical microtubule plus-end(GO:1903754) cytoplasmic microtubule plus-end(GO:1904511)
0.1 1.0 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
0.1 0.7 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.0 2.1 GO:0097228 sperm principal piece(GO:0097228)
0.0 0.3 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.0 0.2 GO:0097058 CRLF-CLCF1 complex(GO:0097058)
0.0 0.9 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.0 6.0 GO:0014704 intercalated disc(GO:0014704)
0.0 0.5 GO:0008540 proteasome regulatory particle, base subcomplex(GO:0008540)
0.0 1.2 GO:0001891 phagocytic cup(GO:0001891)
0.0 2.7 GO:0032420 stereocilium(GO:0032420)
0.0 0.4 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 4.0 GO:0017053 transcriptional repressor complex(GO:0017053)
0.0 0.3 GO:0032585 multivesicular body membrane(GO:0032585)
0.0 1.0 GO:0060077 inhibitory synapse(GO:0060077)
0.0 1.0 GO:0032391 photoreceptor connecting cilium(GO:0032391)
0.0 0.3 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.0 0.6 GO:0030132 clathrin coat of coated pit(GO:0030132)
0.0 0.0 GO:0097132 cyclin D2-CDK6 complex(GO:0097132)
0.0 0.5 GO:0001533 cornified envelope(GO:0001533)
0.0 1.2 GO:0031519 PcG protein complex(GO:0031519)
0.0 0.5 GO:1902562 NuA4 histone acetyltransferase complex(GO:0035267) H4/H2A histone acetyltransferase complex(GO:0043189) H4 histone acetyltransferase complex(GO:1902562)
0.0 2.9 GO:0031225 anchored component of membrane(GO:0031225)
0.0 0.1 GO:0045009 melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.0 0.2 GO:0033270 paranode region of axon(GO:0033270)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 2.2 GO:0070052 collagen V binding(GO:0070052)
0.5 4.1 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.4 3.7 GO:0051434 BH3 domain binding(GO:0051434)
0.3 1.0 GO:0008192 RNA guanylyltransferase activity(GO:0008192)
0.3 5.8 GO:0030235 nitric-oxide synthase regulator activity(GO:0030235)
0.3 1.8 GO:0004966 galanin receptor activity(GO:0004966)
0.3 2.6 GO:0035381 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.2 0.7 GO:0005330 dopamine:sodium symporter activity(GO:0005330)
0.2 4.4 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.2 1.1 GO:0048495 Roundabout binding(GO:0048495)
0.1 0.7 GO:0003986 acetyl-CoA hydrolase activity(GO:0003986)
0.1 0.6 GO:0043812 phosphatidylinositol-4-phosphate phosphatase activity(GO:0043812)
0.1 0.7 GO:0043515 kinetochore binding(GO:0043515)
0.1 4.4 GO:0001671 ATPase activator activity(GO:0001671)
0.1 1.4 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.1 0.4 GO:0004749 ribose phosphate diphosphokinase activity(GO:0004749)
0.1 0.4 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.1 0.3 GO:1902379 chemoattractant activity involved in axon guidance(GO:1902379)
0.1 0.4 GO:0030280 structural constituent of epidermis(GO:0030280)
0.1 0.7 GO:0047134 protein-disulfide reductase activity(GO:0047134)
0.1 1.9 GO:0070182 DNA polymerase binding(GO:0070182)
0.1 3.5 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.1 0.7 GO:0102336 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.1 1.0 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.1 2.8 GO:0003785 actin monomer binding(GO:0003785)
0.1 0.8 GO:0048185 activin binding(GO:0048185)
0.1 1.3 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.1 3.1 GO:0019212 phosphatase inhibitor activity(GO:0019212)
0.0 0.9 GO:0015174 basic amino acid transmembrane transporter activity(GO:0015174)
0.0 0.3 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.0 0.3 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.0 0.2 GO:0031781 melanocortin receptor binding(GO:0031779) type 3 melanocortin receptor binding(GO:0031781) type 4 melanocortin receptor binding(GO:0031782)
0.0 1.6 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.0 0.5 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
0.0 5.5 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 0.3 GO:0000990 transcription factor activity, core RNA polymerase binding(GO:0000990)
0.0 0.7 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0 0.1 GO:0034617 tetrahydrobiopterin binding(GO:0034617)
0.0 4.0 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.2 GO:0008269 JAK pathway signal transduction adaptor activity(GO:0008269)
0.0 0.5 GO:1901702 urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.0 0.3 GO:0005412 glucose:sodium symporter activity(GO:0005412)
0.0 0.1 GO:0031751 D4 dopamine receptor binding(GO:0031751)
0.0 1.7 GO:0005160 transforming growth factor beta receptor binding(GO:0005160)
0.0 0.2 GO:0030550 acetylcholine receptor inhibitor activity(GO:0030550)
0.0 0.2 GO:0050786 RAGE receptor binding(GO:0050786)
0.0 2.1 GO:0004197 cysteine-type endopeptidase activity(GO:0004197)
0.0 0.9 GO:0031683 G-protein beta/gamma-subunit complex binding(GO:0031683)
0.0 0.2 GO:0005127 ciliary neurotrophic factor receptor binding(GO:0005127)
0.0 0.2 GO:0015379 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.0 0.6 GO:0004890 GABA-A receptor activity(GO:0004890)
0.0 0.3 GO:0005355 glucose transmembrane transporter activity(GO:0005355)
0.0 0.4 GO:0048038 quinone binding(GO:0048038)
0.0 0.0 GO:0098770 FBXO family protein binding(GO:0098770)
0.0 0.4 GO:0070001 aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.0 0.3 GO:0038191 neuropilin binding(GO:0038191)
0.0 0.3 GO:0002162 dystroglycan binding(GO:0002162)
0.0 0.5 GO:0001103 RNA polymerase II repressing transcription factor binding(GO:0001103)
0.0 1.7 GO:0008083 growth factor activity(GO:0008083)
0.0 2.0 GO:0047485 protein N-terminus binding(GO:0047485)
0.0 0.4 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.0 0.2 GO:0003993 acid phosphatase activity(GO:0003993)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 3.7 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.1 1.4 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.1 3.9 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.1 3.2 SA B CELL RECEPTOR COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.1 3.4 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.1 4.8 PID PLK1 PATHWAY PLK1 signaling events
0.1 2.8 PID BARD1 PATHWAY BARD1 signaling events
0.1 1.9 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.0 1.0 PID GLYPICAN 1PATHWAY Glypican 1 network
0.0 1.1 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.0 0.6 PID EPHB FWD PATHWAY EPHB forward signaling
0.0 1.1 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 1.8 PID AR PATHWAY Coregulation of Androgen receptor activity
0.0 0.4 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.0 0.9 PID PI3KCI PATHWAY Class I PI3K signaling events
0.0 4.0 NABA SECRETED FACTORS Genes encoding secreted soluble factors

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 2.6 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.2 3.7 REACTOME INFLAMMASOMES Genes involved in Inflammasomes
0.1 1.9 REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY Genes involved in Regulation of the Fanconi anemia pathway
0.1 3.6 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.1 3.9 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.1 1.0 REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.1 4.4 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.1 3.5 REACTOME RECYCLING PATHWAY OF L1 Genes involved in Recycling pathway of L1
0.1 0.9 REACTOME FANCONI ANEMIA PATHWAY Genes involved in Fanconi Anemia pathway
0.0 0.5 REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT Genes involved in Organic cation/anion/zwitterion transport
0.0 1.1 REACTOME ELONGATION ARREST AND RECOVERY Genes involved in Elongation arrest and recovery
0.0 5.6 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0 1.3 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.0 0.6 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.0 1.6 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 0.1 REACTOME DESTABILIZATION OF MRNA BY KSRP Genes involved in Destabilization of mRNA by KSRP
0.0 3.5 REACTOME POTASSIUM CHANNELS Genes involved in Potassium Channels
0.0 0.5 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0 0.4 REACTOME HYALURONAN METABOLISM Genes involved in Hyaluronan metabolism
0.0 0.3 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.0 0.8 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 0.9 REACTOME MEIOTIC SYNAPSIS Genes involved in Meiotic Synapsis
0.0 2.2 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.0 0.5 REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
0.0 0.3 REACTOME L1CAM INTERACTIONS Genes involved in L1CAM interactions
0.0 0.6 REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane