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GSE58827: Dynamics of the Mouse Liver

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Results for Gli2

Z-value: 0.87

Motif logo

Transcription factors associated with Gli2

Gene Symbol Gene ID Gene Info
ENSMUSG00000048402.15 GLI-Kruppel family member GLI2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Gli2mm39_v1_chr1_-_118981341_118981368-0.773.8e-08Click!

Activity profile of Gli2 motif

Sorted Z-values of Gli2 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr1_-_51955054 5.15 ENSMUST00000018561.14
ENSMUST00000114537.9
myosin IB
chr3_+_97536120 4.98 ENSMUST00000107050.8
ENSMUST00000029729.15
ENSMUST00000107049.2
flavin containing monooxygenase 5
chr4_-_154983533 4.85 ENSMUST00000030935.10
ENSMUST00000132281.2
peroxiredoxin like 2B
chr5_-_53370761 4.81 ENSMUST00000031090.8
sel-1 suppressor of lin-12-like 3 (C. elegans)
chr1_-_51955126 4.80 ENSMUST00000046390.14
myosin IB
chr9_+_107454114 3.80 ENSMUST00000112387.9
ENSMUST00000123005.8
ENSMUST00000010195.14
ENSMUST00000144392.2
hyaluronoglucosaminidase 1
chr1_-_180027151 3.59 ENSMUST00000161743.3
coenzyme Q8A
chr8_+_127790772 3.40 ENSMUST00000079777.12
ENSMUST00000160272.8
ENSMUST00000162907.8
ENSMUST00000162536.8
ENSMUST00000026921.13
ENSMUST00000162665.8
ENSMUST00000162602.8
ENSMUST00000160581.8
ENSMUST00000161355.8
ENSMUST00000162531.8
ENSMUST00000160766.8
ENSMUST00000159537.8
par-3 family cell polarity regulator
chr9_+_100525807 3.22 ENSMUST00000133388.2
stromal antigen 1
chr4_-_120955387 2.84 ENSMUST00000058754.9
zinc metallopeptidase, STE24
chr9_+_100525637 2.62 ENSMUST00000041418.13
stromal antigen 1
chr2_-_157408239 2.49 ENSMUST00000109528.9
ENSMUST00000088494.3
bladder cancer associated protein
chr17_-_24428351 2.31 ENSMUST00000024931.6
netrin 3
chr2_-_32271833 2.25 ENSMUST00000146423.2
RIKEN cDNA 1110008P14 gene
chr2_-_121786573 2.19 ENSMUST00000104936.4
MAGE family member B3
chr12_-_70274433 2.19 ENSMUST00000071250.13
liver glycogen phosphorylase
chr2_+_69727599 2.18 ENSMUST00000131553.2
ubiquitin protein ligase E3 component n-recognin 3
chr4_-_46536088 2.09 ENSMUST00000102924.3
ENSMUST00000046897.13
tripartite motif-containing 14
chr9_+_100525501 2.09 ENSMUST00000146312.8
ENSMUST00000129269.8
stromal antigen 1
chr9_+_108924457 2.07 ENSMUST00000072093.13
plexin B1
chr1_-_93406091 1.99 ENSMUST00000188165.2
high density lipoprotein (HDL) binding protein
chr11_+_118913788 1.99 ENSMUST00000026662.8
chromobox 2
chr6_+_137731526 1.90 ENSMUST00000203216.3
ENSMUST00000087675.9
ENSMUST00000203693.3
deoxyribose-phosphate aldolase (putative)
chr8_+_91635192 1.87 ENSMUST00000211403.2
chromodomain helicase DNA binding protein 9
chrX_-_9529189 1.79 ENSMUST00000033519.3
dynein light chain Tctex-type 3
chr8_+_77628916 1.78 ENSMUST00000109912.8
ENSMUST00000128862.2
ENSMUST00000109911.8
nuclear receptor subfamily 3, group C, member 2
chr7_-_81104423 1.75 ENSMUST00000178892.3
ENSMUST00000098331.10
cytoplasmic polyadenylation element binding protein 1
chr16_+_4825216 1.74 ENSMUST00000185147.8
small integral membrane protein 22
chr6_+_113448388 1.74 ENSMUST00000058300.14
interleukin 17 receptor C
chr6_+_137731599 1.74 ENSMUST00000204356.2
deoxyribose-phosphate aldolase (putative)
chr19_-_38113249 1.71 ENSMUST00000112335.4
retinol binding protein 4, plasma
chr1_-_175453117 1.64 ENSMUST00000027810.14
fumarate hydratase 1
chr2_+_160573604 1.62 ENSMUST00000174885.2
ENSMUST00000109462.8
phospholipase C, gamma 1
chr4_+_41760454 1.60 ENSMUST00000108040.8
interleukin 11 receptor, alpha chain 1
chr10_-_127099183 1.56 ENSMUST00000099172.5
kinesin family member 5A
chr7_+_28240262 1.50 ENSMUST00000119180.4
syncollin
chrX_-_73067514 1.50 ENSMUST00000033769.15
ENSMUST00000114352.8
ENSMUST00000068286.12
ENSMUST00000114360.10
ENSMUST00000114354.10
interleukin-1 receptor-associated kinase 1
chr11_+_72686990 1.48 ENSMUST00000069395.7
ENSMUST00000172220.8
zinc finger, ZZ-type with EF hand domain 1
chr10_+_83379805 1.45 ENSMUST00000038388.7
WASH complex subunit 4
chr2_-_37593287 1.44 ENSMUST00000072186.12
spermatid perinuclear RNA binding protein
chr12_-_69771604 1.43 ENSMUST00000021370.10
L-2-hydroxyglutarate dehydrogenase
chr7_-_65020955 1.43 ENSMUST00000102592.10
tight junction protein 1
chr10_-_127098932 1.41 ENSMUST00000217895.2
kinesin family member 5A
chr13_-_54759086 1.40 ENSMUST00000049575.8
clathrin, light polypeptide (Lcb)
chr11_+_70735751 1.39 ENSMUST00000177731.8
ENSMUST00000108533.10
ENSMUST00000081362.13
ENSMUST00000178245.2
rabaptin, RAB GTPase binding effector protein 1
chr19_+_6097111 1.38 ENSMUST00000025723.9
synovial apoptosis inhibitor 1, synoviolin
chr1_-_93406515 1.36 ENSMUST00000170883.8
ENSMUST00000189025.7
high density lipoprotein (HDL) binding protein
chr19_-_38113056 1.33 ENSMUST00000236283.2
retinol binding protein 4, plasma
chr19_+_6097083 1.32 ENSMUST00000134667.8
synovial apoptosis inhibitor 1, synoviolin
chr2_+_121786892 1.32 ENSMUST00000110578.8
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase like 2
chr8_+_120173458 1.29 ENSMUST00000098363.10
N-terminal EF-hand calcium binding protein 2
chr13_-_54759145 1.27 ENSMUST00000091609.11
clathrin, light polypeptide (Lcb)
chr2_-_121211410 1.23 ENSMUST00000038389.15
stereocilin
chrX_+_160500623 1.22 ENSMUST00000061514.8
retinoic acid induced 2
chr15_+_41310815 1.21 ENSMUST00000090096.11
ENSMUST00000110297.10
oxidation resistance 1
chr9_+_44966464 1.20 ENSMUST00000114664.8
myelin protein zero-like 3
chr12_-_32000209 1.19 ENSMUST00000176084.2
ENSMUST00000176103.8
ENSMUST00000167458.9
high mobility group box transcription factor 1
chr8_+_127790626 1.18 ENSMUST00000162309.8
par-3 family cell polarity regulator
chr7_+_81220987 1.14 ENSMUST00000165460.2
WAS protein homolog associated with actin, golgi membranes and microtubules
chr4_-_140376047 1.13 ENSMUST00000105799.8
ENSMUST00000039204.10
ENSMUST00000097820.9
Rho guanine nucleotide exchange factor (GEF) 10-like
chr4_+_155916087 1.10 ENSMUST00000105592.8
ENSMUST00000105591.2
aurora kinase A interacting protein 1
chr11_-_121279062 1.08 ENSMUST00000106107.3
Rab40B, member RAS oncogene family
chr3_+_106943472 1.08 ENSMUST00000052718.5
potassium voltage-gated channel, shaker-related subfamily, member 3
chr9_+_100956145 1.07 ENSMUST00000189616.2
MSL complex subunit 2
chr17_+_24851647 1.05 ENSMUST00000047611.4
nth (endonuclease III)-like 1 (E.coli)
chr1_+_167177545 1.05 ENSMUST00000028004.11
aldehyde dehydrogenase 9, subfamily A1
chr5_-_139805661 1.04 ENSMUST00000147328.2
transmembrane protein 184a
chr12_-_32000169 1.03 ENSMUST00000176520.8
high mobility group box transcription factor 1
chr7_-_144292257 0.94 ENSMUST00000121758.8
anoctamin 1, calcium activated chloride channel
chr14_-_65187287 0.92 ENSMUST00000067843.10
ENSMUST00000176489.8
ENSMUST00000175905.8
ENSMUST00000022544.14
ENSMUST00000175744.8
ENSMUST00000176128.8
homeobox containing 1
chr11_+_70735572 0.90 ENSMUST00000076270.13
ENSMUST00000179114.8
ENSMUST00000100928.11
rabaptin, RAB GTPase binding effector protein 1
chr17_+_28910393 0.89 ENSMUST00000124886.9
ENSMUST00000114758.9
mitogen-activated protein kinase 14
chr11_+_29476423 0.89 ENSMUST00000136351.8
ENSMUST00000020749.13
ENSMUST00000144321.8
ENSMUST00000093239.11
mitochondrial translational initiation factor 2
chr8_-_27664651 0.89 ENSMUST00000054212.7
ENSMUST00000033878.14
ENSMUST00000209377.2
RAB11 family interacting protein 1 (class I)
chr1_-_172418058 0.87 ENSMUST00000065679.8
SLAM family member 8
chr1_-_36484328 0.87 ENSMUST00000125304.8
ENSMUST00000115011.8
lectin, mannose-binding 2-like
chrX_-_140508177 0.84 ENSMUST00000067841.8
insulin receptor substrate 4
chr8_+_85786684 0.84 ENSMUST00000095220.4
F-box and WD-40 domain protein 9
chr18_+_61688329 0.83 ENSMUST00000165123.8
casein kinase 1, alpha 1
chr7_-_65020655 0.82 ENSMUST00000032729.8
tight junction protein 1
chr11_+_29476385 0.82 ENSMUST00000133452.8
mitochondrial translational initiation factor 2
chr16_+_19579651 0.82 ENSMUST00000119468.2
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5
chr7_+_101034604 0.81 ENSMUST00000130016.8
ENSMUST00000134143.2
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1
chr7_+_40547608 0.80 ENSMUST00000044705.12
V-set and transmembrane domain containing 2B
chr8_-_13939964 0.80 ENSMUST00000209371.2
coordinator of PRMT5, differentiation stimulator
chr11_+_72687080 0.79 ENSMUST00000207107.2
zinc finger, ZZ-type with EF hand domain 1
chr13_-_48779047 0.74 ENSMUST00000222028.2
protein tyrosine phosphatase domain containing 1
chr7_-_144292288 0.74 ENSMUST00000238848.2
ENSMUST00000118556.9
ENSMUST00000033393.15
anoctamin 1, calcium activated chloride channel
chr5_-_92231517 0.72 ENSMUST00000202258.4
ENSMUST00000113127.7
GTPase activating protein (SH3 domain) binding protein 2
chr4_+_43401232 0.72 ENSMUST00000125399.2
RUN and SH3 domain containing 2
chr17_-_56916771 0.71 ENSMUST00000052832.6
mitochondrial contact site and cristae organizing system subunit 13
chr18_-_35348049 0.71 ENSMUST00000091636.5
ENSMUST00000236680.2
leucine rich repeat transmembrane neuronal 2
chr11_+_106256298 0.70 ENSMUST00000009354.10
proline rich 29
chr7_-_132724344 0.67 ENSMUST00000167218.8
C-terminal binding protein 2
chrX_+_160500051 0.64 ENSMUST00000112338.2
retinoic acid induced 2
chr3_-_59102517 0.61 ENSMUST00000200095.2
G protein-coupled receptor 87
chr8_-_13940234 0.61 ENSMUST00000033839.9
coordinator of PRMT5, differentiation stimulator
chr17_+_45874800 0.59 ENSMUST00000224905.2
ENSMUST00000226086.2
ENSMUST00000041353.7
solute carrier family 35, member B2
chr2_+_180141686 0.59 ENSMUST00000029084.9
neurotensin receptor 1
chr11_+_68582897 0.59 ENSMUST00000108673.8
myosin, heavy polypeptide 10, non-muscle
chr10_-_34003933 0.58 ENSMUST00000062784.8
calcium homeostasis modulator family member 6
chr7_-_132725041 0.57 ENSMUST00000171022.8
C-terminal binding protein 2
chr11_-_94595325 0.57 ENSMUST00000069852.2
predicted gene 11541
chr13_-_48779072 0.54 ENSMUST00000035824.11
protein tyrosine phosphatase domain containing 1
chr7_-_57159119 0.53 ENSMUST00000206382.2
gamma-aminobutyric acid (GABA) A receptor, subunit alpha 5
chr11_+_73220553 0.52 ENSMUST00000092926.11
ENSMUST00000117445.2
spermatogenesis associated 22
predicted gene, 49340
chrX_+_7439839 0.52 ENSMUST00000144719.9
ENSMUST00000234896.2
Foxp3 regulating long intergenic noncoding RNA
forkhead box P3
chrX_-_166165743 0.51 ENSMUST00000026839.5
phosphoribosyl pyrophosphate synthetase 2
chr16_+_8647959 0.50 ENSMUST00000023150.7
RIKEN cDNA 1810013L24 gene
chr8_+_10056631 0.49 ENSMUST00000207792.3
tumor necrosis factor (ligand) superfamily, member 13b
chr17_-_25716189 0.48 ENSMUST00000165183.10
ENSMUST00000051864.5
somatostatin receptor 5
chr12_-_32000534 0.48 ENSMUST00000172314.9
high mobility group box transcription factor 1
chr18_+_61688378 0.48 ENSMUST00000165721.8
ENSMUST00000115246.9
ENSMUST00000166990.8
ENSMUST00000163205.8
ENSMUST00000170862.8
casein kinase 1, alpha 1
chr3_-_85909798 0.48 ENSMUST00000061343.4
protease, serine 48
chr7_-_132725137 0.48 ENSMUST00000170459.8
C-terminal binding protein 2
chr11_+_70506716 0.43 ENSMUST00000144960.2
RIKEN cDNA 4930544D05 gene
chr11_-_100741550 0.42 ENSMUST00000004143.3
signal transducer and activator of transcription 5B
chr18_+_35347983 0.42 ENSMUST00000235449.2
ENSMUST00000235269.2
catenin (cadherin associated protein), alpha 1
chr2_+_164328375 0.41 ENSMUST00000069385.15
ENSMUST00000143690.8
dysbindin (dystrobrevin binding protein 1) domain containing 2
chr11_+_70453666 0.41 ENSMUST00000072237.13
ENSMUST00000072873.14
misshapen-like kinase 1 (zebrafish)
chr15_-_78602313 0.40 ENSMUST00000229441.2
leucine rich repeat and fibronectin type III, extracellular 2
chr11_+_115921129 0.40 ENSMUST00000021116.12
ENSMUST00000106452.2
unkempt family zinc finger
chr9_+_62249730 0.40 ENSMUST00000156461.2
acidic (leucine-rich) nuclear phosphoprotein 32 family, member A
chr2_+_164327988 0.39 ENSMUST00000109350.9
dysbindin (dystrobrevin binding protein 1) domain containing 2
chr12_+_38830081 0.36 ENSMUST00000095767.11
ets variant 1
chr5_+_8943677 0.36 ENSMUST00000003717.13
ATP-binding cassette, sub-family B (MDR/TAP), member 4
chr8_+_10056654 0.35 ENSMUST00000033892.9
tumor necrosis factor (ligand) superfamily, member 13b
chr7_+_12615091 0.35 ENSMUST00000144578.2
zinc finger protein 128
chr5_-_24732200 0.35 ENSMUST00000088311.6
gastrulation brain homeobox 1
chr16_-_3895642 0.34 ENSMUST00000006137.9
TNF receptor-associated protein 1
chr16_-_31133622 0.34 ENSMUST00000115230.2
ENSMUST00000130560.8
apolipoprotein D
chr6_-_124441731 0.34 ENSMUST00000008297.5
calsyntenin 3
chr1_-_119924920 0.34 ENSMUST00000174370.8
ENSMUST00000174458.2
cilia and flagella associated protein 221
chr8_+_71207326 0.33 ENSMUST00000110093.9
ENSMUST00000143118.3
ENSMUST00000034301.12
ENSMUST00000110090.8
RAB3A, member RAS oncogene family
chr11_+_70453724 0.32 ENSMUST00000102559.11
misshapen-like kinase 1 (zebrafish)
chr8_+_27937691 0.32 ENSMUST00000081321.5
POTE ankyrin domain family, member G
chr7_+_44813363 0.32 ENSMUST00000085374.7
ENSMUST00000209634.2
solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 7
chr11_-_68762664 0.32 ENSMUST00000101017.9
nudE neurodevelopment protein 1 like 1
chr2_+_121786444 0.31 ENSMUST00000036647.13
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase like 2
chr4_-_126150066 0.30 ENSMUST00000122129.8
ENSMUST00000061143.15
ENSMUST00000106132.3
MAP7 domain containing 1
chr7_+_130294262 0.29 ENSMUST00000033141.7
transforming, acidic coiled-coil containing protein 2
chrX_-_95000496 0.29 ENSMUST00000079987.13
ENSMUST00000113864.3
LAS1-like (S. cerevisiae)
chr10_-_128727542 0.29 ENSMUST00000026408.7
growth differentiation factor 11
chr7_+_140908033 0.28 ENSMUST00000133012.8
ENSMUST00000026578.14
transmembrane protein 80
chr11_+_117198958 0.26 ENSMUST00000153668.8
septin 9
chr2_-_104542467 0.25 ENSMUST00000111118.8
ENSMUST00000028597.4
t-complex 11 like 1
chr5_-_71253107 0.25 ENSMUST00000197284.5
gamma-aminobutyric acid (GABA) A receptor, subunit alpha 2
chr5_+_147206769 0.24 ENSMUST00000085591.7
pancreatic and duodenal homeobox 1
chr17_-_84495364 0.24 ENSMUST00000060366.7
zinc finger protein 36, C3H type-like 2
chr11_+_70453806 0.24 ENSMUST00000079244.12
ENSMUST00000102558.11
misshapen-like kinase 1 (zebrafish)
chr6_-_38614155 0.24 ENSMUST00000096030.7
ENSMUST00000201345.2
killer cell lectin-like receptor subfamily G, member 2
chr17_-_52139693 0.23 ENSMUST00000144331.8
special AT-rich sequence binding protein 1
chr2_+_74566740 0.23 ENSMUST00000111982.8
homeobox D3
chr14_-_55354392 0.21 ENSMUST00000022819.13
junctophilin 4
chr5_+_73563418 0.20 ENSMUST00000031040.13
ENSMUST00000065543.8
cell wall biogenesis 43 C-terminal homolog
chr4_-_135699205 0.19 ENSMUST00000105852.8
lysophospholipase 2
chr4_+_63133639 0.18 ENSMUST00000036300.13
collagen, type XXVII, alpha 1
chr7_-_132725075 0.18 ENSMUST00000163601.8
ENSMUST00000033269.15
ENSMUST00000124096.8
C-terminal binding protein 2
fibroblast growth factor receptor 2
chrX_+_99773784 0.18 ENSMUST00000113744.2
glycerophosphodiester phosphodiesterase domain containing 2
chr1_-_72576089 0.18 ENSMUST00000047786.6
membrane associated ring-CH-type finger 4
chr4_+_116953218 0.15 ENSMUST00000030443.12
patched 2
chr18_+_38383297 0.12 ENSMUST00000025314.7
ENSMUST00000236078.2
DAP3 binding cell death enhancer 1
chr9_+_107805647 0.12 ENSMUST00000085073.2
actin-like 11
chr2_-_120439764 0.11 ENSMUST00000102496.8
leucine rich repeat containing 57
chr11_-_41891359 0.10 ENSMUST00000070735.10
gamma-aminobutyric acid (GABA) A receptor, subunit gamma 2
chr2_-_120439981 0.09 ENSMUST00000133612.2
ENSMUST00000102498.8
ENSMUST00000102499.8
leucine rich repeat containing 57
chr9_+_24009292 0.09 ENSMUST00000133787.8
ENSMUST00000059650.11
neuropeptide S receptor 1
chr16_+_3648742 0.08 ENSMUST00000214238.2
ENSMUST00000214590.2
olfactory receptor 15
chr2_-_120439826 0.08 ENSMUST00000102497.10
leucine rich repeat containing 57
chr12_+_38830283 0.07 ENSMUST00000162563.8
ENSMUST00000161164.8
ENSMUST00000160996.8
ets variant 1
chr1_+_55127110 0.06 ENSMUST00000075242.7
heat shock protein 1 (chaperonin 10)
chr9_+_20943350 0.05 ENSMUST00000019616.6
intercellular adhesion molecule 5, telencephalin
chrX_+_99773523 0.05 ENSMUST00000019503.14
glycerophosphodiester phosphodiesterase domain containing 2
chr4_+_155915729 0.04 ENSMUST00000139651.8
ENSMUST00000084097.12
aurora kinase A interacting protein 1
chr1_+_97697881 0.04 ENSMUST00000112844.10
ENSMUST00000112842.8
ENSMUST00000027571.13
gypsy retrotransposon integrase 1
chr4_+_134879807 0.03 ENSMUST00000119564.2
runt related transcription factor 3
chr9_-_69668204 0.03 ENSMUST00000071281.5
forkhead box B1
chr4_+_40472180 0.02 ENSMUST00000049655.3
transmembrane protein 215
chr2_+_71042050 0.01 ENSMUST00000112142.8
ENSMUST00000112139.8
ENSMUST00000112140.8
ENSMUST00000112138.8
dynein cytoplasmic 1 intermediate chain 2
chr11_-_118800314 0.00 ENSMUST00000117731.8
ENSMUST00000106278.9
ENSMUST00000120061.8
ENSMUST00000017576.11
RNA binding protein, fox-1 homolog (C. elegans) 3
chr17_-_24851549 0.00 ENSMUST00000227607.2
ENSMUST00000227509.2
ENSMUST00000227745.2
TSC complex subunit 2

Network of associatons between targets according to the STRING database.

First level regulatory network of Gli2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 3.8 GO:1900104 hyaluranon cable assembly(GO:0036118) regulation of hyaluranon cable assembly(GO:1900104) positive regulation of hyaluranon cable assembly(GO:1900106)
0.9 2.8 GO:0030327 prenylated protein catabolic process(GO:0030327)
0.7 2.7 GO:0006015 5-phosphoribose 1-diphosphate biosynthetic process(GO:0006015) 5-phosphoribose 1-diphosphate metabolic process(GO:0046391)
0.7 4.6 GO:0003383 apical constriction(GO:0003383)
0.6 3.0 GO:0048807 female genitalia morphogenesis(GO:0048807)
0.6 3.6 GO:0046121 deoxyribonucleoside catabolic process(GO:0046121)
0.6 3.0 GO:0098971 anterograde dendritic transport of neurotransmitter receptor complex(GO:0098971)
0.5 1.6 GO:0006106 fumarate metabolic process(GO:0006106)
0.5 2.2 GO:0071596 ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596)
0.5 2.1 GO:1900220 semaphorin-plexin signaling pathway involved in bone trabecula morphogenesis(GO:1900220)
0.4 1.8 GO:0031959 mineralocorticoid receptor signaling pathway(GO:0031959)
0.4 1.3 GO:1904020 regulation of G-protein coupled receptor internalization(GO:1904020)
0.4 1.1 GO:0006296 base-excision repair, AP site formation(GO:0006285) nucleotide-excision repair, DNA incision, 5'-to lesion(GO:0006296)
0.3 0.9 GO:1902623 negative regulation of neutrophil migration(GO:1902623)
0.2 1.4 GO:0043985 histone H4-R3 methylation(GO:0043985)
0.2 2.2 GO:2000766 negative regulation of cytoplasmic translation(GO:2000766)
0.2 1.5 GO:0090370 negative regulation of cholesterol efflux(GO:0090370)
0.2 1.0 GO:0018992 germ-line sex determination(GO:0018992)
0.2 0.5 GO:0002851 positive regulation of tolerance induction dependent upon immune response(GO:0002654) regulation of peripheral tolerance induction(GO:0002658) positive regulation of peripheral tolerance induction(GO:0002660) regulation of peripheral T cell tolerance induction(GO:0002849) positive regulation of peripheral T cell tolerance induction(GO:0002851)
0.2 1.7 GO:0015705 iodide transport(GO:0015705)
0.1 3.6 GO:0006744 ubiquinone biosynthetic process(GO:0006744)
0.1 0.9 GO:0070164 negative regulation of adiponectin secretion(GO:0070164)
0.1 2.7 GO:0010745 negative regulation of macrophage derived foam cell differentiation(GO:0010745)
0.1 2.3 GO:0090557 establishment of endothelial intestinal barrier(GO:0090557)
0.1 0.8 GO:0002636 positive regulation of germinal center formation(GO:0002636) B cell costimulation(GO:0031296)
0.1 0.4 GO:1903413 response to bile acid(GO:1903412) cellular response to bile acid(GO:1903413)
0.1 0.6 GO:0090238 positive regulation of arachidonic acid secretion(GO:0090238)
0.1 0.4 GO:0097374 sensory neuron axon guidance(GO:0097374)
0.1 1.6 GO:1901339 regulation of store-operated calcium channel activity(GO:1901339)
0.1 0.3 GO:1901856 negative regulation of cellular respiration(GO:1901856)
0.1 0.3 GO:2000097 negative regulation of lipoprotein oxidation(GO:0034443) regulation of smooth muscle cell-matrix adhesion(GO:2000097)
0.1 0.9 GO:0014835 myoblast differentiation involved in skeletal muscle regeneration(GO:0014835) positive regulation of interleukin-12 secretion(GO:2001184)
0.1 0.3 GO:0097401 synaptic vesicle lumen acidification(GO:0097401)
0.1 3.0 GO:1902236 negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway(GO:1902236)
0.1 1.7 GO:1900017 positive regulation of cytokine production involved in inflammatory response(GO:1900017)
0.1 0.5 GO:0000711 meiotic DNA repair synthesis(GO:0000711)
0.1 1.0 GO:0042136 neurotransmitter biosynthetic process(GO:0042136)
0.1 1.4 GO:0090527 actin filament reorganization(GO:0090527)
0.1 10.0 GO:0006892 post-Golgi vesicle-mediated transport(GO:0006892)
0.1 1.3 GO:1904424 regulation of GTP binding(GO:1904424)
0.1 1.8 GO:0035563 positive regulation of chromatin binding(GO:0035563)
0.1 0.4 GO:2001045 negative regulation of integrin-mediated signaling pathway(GO:2001045)
0.1 0.6 GO:0035589 G-protein coupled purinergic nucleotide receptor signaling pathway(GO:0035589)
0.1 1.6 GO:0046697 decidualization(GO:0046697)
0.1 0.3 GO:0099558 maintenance of synapse structure(GO:0099558)
0.1 0.6 GO:0051503 adenine nucleotide transport(GO:0051503)
0.1 0.2 GO:0002084 protein depalmitoylation(GO:0002084) macromolecule depalmitoylation(GO:0098734)
0.1 2.5 GO:0030262 apoptotic nuclear changes(GO:0030262)
0.1 1.2 GO:1902083 negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.1 0.4 GO:0046544 development of secondary male sexual characteristics(GO:0046544)
0.1 1.0 GO:0070050 neuron cellular homeostasis(GO:0070050)
0.1 1.6 GO:0046827 positive regulation of protein export from nucleus(GO:0046827)
0.0 0.3 GO:1902474 positive regulation of protein localization to synapse(GO:1902474)
0.0 1.2 GO:0060088 auditory receptor cell stereocilium organization(GO:0060088)
0.0 1.1 GO:0071501 response to sterol depletion(GO:0006991) SREBP signaling pathway(GO:0032933) cellular response to sterol depletion(GO:0071501)
0.0 1.3 GO:0032897 negative regulation of viral transcription(GO:0032897)
0.0 0.7 GO:0002091 negative regulation of receptor internalization(GO:0002091)
0.0 2.3 GO:0007520 myoblast fusion(GO:0007520)
0.0 0.2 GO:0021615 glossopharyngeal nerve morphogenesis(GO:0021615)
0.0 1.9 GO:0007638 mechanosensory behavior(GO:0007638)
0.0 0.8 GO:0001921 positive regulation of receptor recycling(GO:0001921)
0.0 0.7 GO:0034063 stress granule assembly(GO:0034063)
0.0 1.1 GO:0043984 histone H4-K16 acetylation(GO:0043984)
0.0 0.3 GO:0030397 membrane disassembly(GO:0030397) nuclear envelope disassembly(GO:0051081)
0.0 0.0 GO:0021855 hypothalamus cell migration(GO:0021855)
0.0 0.1 GO:1903999 negative regulation of eating behavior(GO:1903999)
0.0 1.4 GO:0007032 endosome organization(GO:0007032)
0.0 2.7 GO:0072583 clathrin-mediated endocytosis(GO:0072583)
0.0 0.2 GO:1904628 response to phorbol 13-acetate 12-myristate(GO:1904627) cellular response to phorbol 13-acetate 12-myristate(GO:1904628)
0.0 0.2 GO:0003431 growth plate cartilage chondrocyte development(GO:0003431)
0.0 0.3 GO:0030953 astral microtubule organization(GO:0030953)
0.0 3.4 GO:0008203 cholesterol metabolic process(GO:0008203)
0.0 0.3 GO:0000478 endonucleolytic cleavage involved in rRNA processing(GO:0000478)
0.0 7.9 GO:0007059 chromosome segregation(GO:0007059)
0.0 0.5 GO:0032467 positive regulation of cytokinesis(GO:0032467)
0.0 0.2 GO:0009957 epidermal cell fate specification(GO:0009957)
0.0 0.5 GO:0060384 innervation(GO:0060384)
0.0 0.2 GO:2001256 regulation of store-operated calcium entry(GO:2001256)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 4.6 GO:0033269 internode region of axon(GO:0033269)
0.5 2.7 GO:0000839 Hrd1p ubiquitin ligase ERAD-L complex(GO:0000839)
0.3 10.0 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.2 2.7 GO:0030130 clathrin coat of trans-Golgi network vesicle(GO:0030130)
0.2 1.1 GO:0072487 MSL complex(GO:0072487)
0.1 0.6 GO:0032280 symmetric synapse(GO:0032280)
0.1 1.7 GO:0072687 meiotic spindle(GO:0072687)
0.1 2.6 GO:0046581 intercellular canaliculus(GO:0046581)
0.1 0.5 GO:0002189 ribose phosphate diphosphokinase complex(GO:0002189)
0.1 3.0 GO:0035253 ciliary rootlet(GO:0035253)
0.1 1.1 GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.1 1.2 GO:0060091 kinocilium(GO:0060091)
0.1 2.0 GO:0035102 PRC1 complex(GO:0035102)
0.1 1.4 GO:0071203 WASH complex(GO:0071203)
0.1 1.6 GO:0045239 tricarboxylic acid cycle enzyme complex(GO:0045239)
0.1 1.3 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.1 3.4 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.0 0.9 GO:0097470 ribbon synapse(GO:0097470)
0.0 3.6 GO:0030667 secretory granule membrane(GO:0030667)
0.0 0.4 GO:0016342 catenin complex(GO:0016342)
0.0 0.9 GO:0005697 telomerase holoenzyme complex(GO:0005697)
0.0 0.3 GO:0060053 neurofilament cytoskeleton(GO:0060053)
0.0 0.6 GO:0030285 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.0 0.2 GO:0030314 junctional membrane complex(GO:0030314)
0.0 3.1 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)
0.0 0.8 GO:0030672 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.0 1.5 GO:0005811 lipid particle(GO:0005811)
0.0 0.2 GO:0098643 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.0 2.3 GO:0030139 endocytic vesicle(GO:0030139)
0.0 0.5 GO:0032809 neuronal cell body membrane(GO:0032809)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 3.0 GO:0034632 retinol transporter activity(GO:0034632)
0.9 3.5 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.6 1.8 GO:0017082 mineralocorticoid receptor activity(GO:0017082)
0.5 2.2 GO:0008184 glycogen phosphorylase activity(GO:0008184)
0.5 5.0 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.4 1.6 GO:0019970 interleukin-11 receptor activity(GO:0004921) interleukin-11 binding(GO:0019970)
0.3 8.0 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.3 1.3 GO:0031687 A2A adenosine receptor binding(GO:0031687)
0.3 1.7 GO:0015111 iodide transmembrane transporter activity(GO:0015111)
0.3 0.8 GO:0047256 beta-galactosyl-N-acetylglucosaminylgalactosylglucosyl-ceramide beta-1,3-acetylglucosaminyltransferase activity(GO:0008457) lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase activity(GO:0047256)
0.3 1.1 GO:0000702 oxidized base lesion DNA N-glycosylase activity(GO:0000702)
0.2 0.6 GO:0046964 3'-phosphoadenosine 5'-phosphosulfate transmembrane transporter activity(GO:0046964)
0.2 0.6 GO:0016492 G-protein coupled neurotensin receptor activity(GO:0016492)
0.2 1.7 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.2 2.3 GO:0071253 connexin binding(GO:0071253)
0.2 2.7 GO:0032050 clathrin heavy chain binding(GO:0032050)
0.2 3.6 GO:0016832 aldehyde-lyase activity(GO:0016832)
0.2 2.1 GO:0017154 semaphorin receptor activity(GO:0017154)
0.2 2.7 GO:1904264 ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.1 1.0 GO:0004028 3-chloroallyl aldehyde dehydrogenase activity(GO:0004028)
0.1 0.5 GO:0004749 ribose phosphate diphosphokinase activity(GO:0004749)
0.1 2.0 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.1 1.6 GO:0005168 neurotrophin TRKA receptor binding(GO:0005168)
0.1 0.9 GO:0003720 telomerase activity(GO:0003720) RNA-directed DNA polymerase activity(GO:0003964)
0.1 1.4 GO:0051525 NFAT protein binding(GO:0051525)
0.1 0.9 GO:0016618 hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267)
0.1 1.1 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.1 5.4 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.1 3.6 GO:0043531 ADP binding(GO:0043531)
0.1 0.3 GO:0015319 sodium:inorganic phosphate symporter activity(GO:0015319) sodium-dependent phosphate transmembrane transporter activity(GO:0015321)
0.1 0.3 GO:0070012 oligopeptidase activity(GO:0070012)
0.1 1.5 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.1 1.0 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.1 0.4 GO:0090554 phosphatidylcholine-translocating ATPase activity(GO:0090554)
0.1 1.1 GO:0015271 outward rectifier potassium channel activity(GO:0015271)
0.0 0.7 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 3.0 GO:0019894 kinesin binding(GO:0019894)
0.0 0.4 GO:1990715 mRNA CDS binding(GO:1990715)
0.0 0.6 GO:0045028 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.0 0.3 GO:0022851 GABA-gated chloride ion channel activity(GO:0022851)
0.0 0.5 GO:0050811 GABA receptor binding(GO:0050811)
0.0 2.8 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 2.0 GO:0035064 methylated histone binding(GO:0035064)
0.0 0.2 GO:0008889 glycerophosphodiester phosphodiesterase activity(GO:0008889)
0.0 0.2 GO:0008158 smoothened binding(GO:0005119) hedgehog receptor activity(GO:0008158)
0.0 1.6 GO:0016836 hydro-lyase activity(GO:0016836)
0.0 0.2 GO:0098599 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.0 1.4 GO:0003743 translation initiation factor activity(GO:0003743)
0.0 0.8 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 2.6 GO:0008083 growth factor activity(GO:0008083)
0.0 0.8 GO:0005158 insulin receptor binding(GO:0005158)
0.0 0.9 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.0 0.4 GO:0045295 gamma-catenin binding(GO:0045295)
0.0 1.4 GO:0003725 double-stranded RNA binding(GO:0003725)
0.0 0.3 GO:0031489 myosin V binding(GO:0031489)
0.0 1.8 GO:0042393 histone binding(GO:0042393)
0.0 0.4 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.0 2.6 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.7 PID ARF 3PATHWAY Arf1 pathway
0.1 5.4 SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES Genes related to the insulin receptor pathway
0.1 2.7 PID MYC PATHWAY C-MYC pathway
0.1 3.9 PID NEPHRIN NEPH1 PATHWAY Nephrin/Neph1 signaling in the kidney podocyte
0.1 3.2 PID AURORA A PATHWAY Aurora A signaling
0.0 1.3 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.0 1.3 PID BETA CATENIN DEG PATHWAY Degradation of beta catenin
0.0 1.5 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.0 0.4 PID IL5 PATHWAY IL5-mediated signaling events
0.0 0.4 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.0 3.8 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 1.0 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.0 2.3 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 3.8 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.3 1.3 REACTOME SIGNALING BY WNT Genes involved in Signaling by Wnt
0.2 4.6 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.1 7.9 REACTOME MEIOTIC SYNAPSIS Genes involved in Meiotic Synapsis
0.1 2.7 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.1 1.5 REACTOME NFKB IS ACTIVATED AND SIGNALS SURVIVAL Genes involved in NF-kB is activated and signals survival
0.1 1.6 REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING Genes involved in Role of second messengers in netrin-1 signaling
0.1 2.2 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.1 2.3 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.1 3.0 REACTOME KINESINS Genes involved in Kinesins
0.1 0.9 REACTOME DSCAM INTERACTIONS Genes involved in DSCAM interactions
0.0 2.7 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0 2.7 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 0.4 REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.0 0.3 REACTOME ACETYLCHOLINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Acetylcholine Neurotransmitter Release Cycle
0.0 0.3 REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
0.0 1.4 REACTOME PYRUVATE METABOLISM AND CITRIC ACID TCA CYCLE Genes involved in Pyruvate metabolism and Citric Acid (TCA) cycle
0.0 0.5 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.0 0.4 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.0 1.1 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.0 1.8 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 2.1 REACTOME G ALPHA1213 SIGNALLING EVENTS Genes involved in G alpha (12/13) signalling events
0.0 0.8 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.0 0.6 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules