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GSE58827: Dynamics of the Mouse Liver

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Results for Gli3_Zic1

Z-value: 0.99

Motif logo

Transcription factors associated with Gli3_Zic1

Gene Symbol Gene ID Gene Info
ENSMUSG00000021318.16 GLI-Kruppel family member GLI3
ENSMUSG00000032368.15 zinc finger protein of the cerebellum 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Gli3mm39_v1_chr13_+_15638466_156385650.411.4e-02Click!
Zic1mm39_v1_chr9_-_91247831_912478680.096.2e-01Click!

Activity profile of Gli3_Zic1 motif

Sorted Z-values of Gli3_Zic1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr11_+_115353290 7.94 ENSMUST00000106532.4
ENSMUST00000092445.12
ENSMUST00000153466.2
solute carrier family 16 (monocarboxylic acid transporters), member 5
chr1_+_72863641 6.08 ENSMUST00000047328.11
insulin-like growth factor binding protein 2
chr7_-_142211203 5.00 ENSMUST00000097936.9
ENSMUST00000000033.12
insulin-like growth factor 2
chr9_+_62765362 3.51 ENSMUST00000213643.2
ENSMUST00000034777.14
ENSMUST00000163820.3
ENSMUST00000215870.2
ENSMUST00000214633.2
ENSMUST00000215968.2
calmodulin-like 4
chr15_-_91075933 2.40 ENSMUST00000069511.8
ATP-binding cassette, sub-family D (ALD), member 2
chr8_+_69333143 2.25 ENSMUST00000015712.15
lipoprotein lipase
chr6_-_101354858 2.22 ENSMUST00000075994.11
PDZ domain containing RING finger 3
chr4_+_123127349 2.22 ENSMUST00000040821.5
hairy/enhancer-of-split related with YRPW motif-like
chr7_-_19504446 2.08 ENSMUST00000003061.14
basal cell adhesion molecule
chr11_-_116545071 1.93 ENSMUST00000021166.6
cytoglobin
chr14_+_55797934 1.66 ENSMUST00000121622.8
ENSMUST00000143431.2
ENSMUST00000150481.8
DDB1 and CUL4 associated factor 11
chr9_+_77824646 1.66 ENSMUST00000034904.14
ELOVL family member 5, elongation of long chain fatty acids (yeast)
chr19_+_4761181 1.57 ENSMUST00000008991.8
spectrin beta, non-erythrocytic 2
chr14_+_14475188 1.57 ENSMUST00000026315.8
deoxyribonuclease 1-like 3
chr7_+_28240262 1.57 ENSMUST00000119180.4
syncollin
chr19_+_42034231 1.55 ENSMUST00000172244.8
ENSMUST00000081714.5
4-hydroxy-2-oxoglutarate aldolase 1
chr6_+_30738043 1.51 ENSMUST00000163949.9
ENSMUST00000124665.3
mesoderm specific transcript
chr14_+_55798517 1.51 ENSMUST00000117701.8
DDB1 and CUL4 associated factor 11
chr14_+_55798362 1.47 ENSMUST00000072530.11
ENSMUST00000128490.9
DDB1 and CUL4 associated factor 11
chr19_+_4282487 1.42 ENSMUST00000235306.2
polymerase (DNA-directed), delta 4
chr10_+_87357657 1.41 ENSMUST00000020241.17
phenylalanine hydroxylase
chr19_-_38113249 1.40 ENSMUST00000112335.4
retinol binding protein 4, plasma
chr19_+_52252735 1.39 ENSMUST00000039652.6
insulin I
chr10_+_87357816 1.33 ENSMUST00000218573.2
phenylalanine hydroxylase
chr2_-_29142965 1.32 ENSMUST00000155949.2
ENSMUST00000154682.8
ENSMUST00000028141.6
ENSMUST00000071201.5
RIKEN cDNA 6530402F18 gene
netrin G2
chr19_+_4281953 1.32 ENSMUST00000025773.5
polymerase (DNA-directed), delta 4
chr1_-_134163102 1.31 ENSMUST00000187631.2
ENSMUST00000038191.8
ENSMUST00000086465.6
adenosine A1 receptor
chr10_+_87357782 1.27 ENSMUST00000219813.2
phenylalanine hydroxylase
chr4_+_131649001 1.26 ENSMUST00000094666.4
transmembrane protein 200B
chr2_-_91762033 1.24 ENSMUST00000111309.8
ENSMUST00000090602.6
midkine
chr19_-_38113056 1.23 ENSMUST00000236283.2
retinol binding protein 4, plasma
chr2_-_92264374 1.22 ENSMUST00000111278.2
ENSMUST00000090559.12
cryptochrome 2 (photolyase-like)
chr18_-_38734389 1.21 ENSMUST00000025295.8
sprouty RTK signaling antagonist 4
chr5_+_30745447 1.20 ENSMUST00000066295.5
potassium channel, subfamily K, member 3
chr7_-_142209755 1.20 ENSMUST00000178921.2
insulin-like growth factor 2
chr13_+_56586156 1.19 ENSMUST00000021971.6
solute carrier family 25, member 48
chr5_+_31454787 1.13 ENSMUST00000201166.4
ENSMUST00000072228.9
glucokinase regulatory protein
chr2_-_91762119 1.13 ENSMUST00000069423.13
midkine
chr7_-_126073994 1.13 ENSMUST00000205733.2
ENSMUST00000205889.2
SH2B adaptor protein 1
chr1_-_134162231 1.12 ENSMUST00000169927.2
adenosine A1 receptor
chr5_+_31454939 1.11 ENSMUST00000201675.3
glucokinase regulatory protein
chr4_+_131648509 1.10 ENSMUST00000238733.2
transmembrane protein 200B
chr9_+_103940879 1.09 ENSMUST00000047799.13
ENSMUST00000189998.3
acyl-Coenzyme A dehydrogenase family, member 11
chr5_+_93241287 1.07 ENSMUST00000074733.11
ENSMUST00000201700.4
ENSMUST00000202196.4
ENSMUST00000202308.4
septin 11
chr19_+_4282040 1.05 ENSMUST00000237518.2
polymerase (DNA-directed), delta 4
chr17_-_35081129 1.03 ENSMUST00000154526.8
complement factor B
chr11_-_96714813 0.98 ENSMUST00000142065.2
ENSMUST00000167110.8
nuclear factor, erythroid derived 2,-like 1
chr17_-_35081456 0.96 ENSMUST00000025229.11
ENSMUST00000176203.9
ENSMUST00000128767.8
complement factor B
chr19_-_38113696 0.94 ENSMUST00000025951.14
ENSMUST00000237287.2
retinol binding protein 4, plasma
chr19_+_4771089 0.94 ENSMUST00000238976.3
spectrin beta, non-erythrocytic 2
chr14_+_33662976 0.93 ENSMUST00000100720.2
growth differentiation factor 2
chr5_+_117457126 0.93 ENSMUST00000111967.8
V-set and immunoglobulin domain containing 10
chr6_-_18030584 0.92 ENSMUST00000010941.6
wingless-type MMTV integration site family, member 2
chr6_-_113508536 0.90 ENSMUST00000032425.7
ER membrane protein complex subunit 3
chrX_-_93585668 0.89 ENSMUST00000026142.8
MAGE family member D1
chr4_-_128856213 0.88 ENSMUST00000119354.8
ENSMUST00000106068.8
ENSMUST00000030581.10
antizyme inhibitor 2
chr16_-_84970617 0.87 ENSMUST00000226232.2
ENSMUST00000227021.2
ENSMUST00000005406.12
ENSMUST00000227723.2
amyloid beta (A4) precursor protein
chr11_+_118324652 0.85 ENSMUST00000106286.3
C1q and tumor necrosis factor related protein 1
chr8_-_65146079 0.85 ENSMUST00000048967.9
carboxypeptidase E
chr16_-_84970580 0.85 ENSMUST00000227737.2
ENSMUST00000226801.2
amyloid beta (A4) precursor protein
chr9_+_50663171 0.84 ENSMUST00000214609.2
crystallin, alpha B
chr2_+_15060051 0.84 ENSMUST00000069870.11
ENSMUST00000239125.2
ENSMUST00000193836.3
ADP-ribosylation factor-like 5B
chr7_-_139696308 0.83 ENSMUST00000026538.13
enoyl Coenzyme A hydratase, short chain, 1, mitochondrial
chr2_+_150628655 0.79 ENSMUST00000045441.8
brain glycogen phosphorylase
chr11_+_68986043 0.77 ENSMUST00000101004.9
period circadian clock 1
chr5_+_93241385 0.75 ENSMUST00000201421.4
ENSMUST00000202415.4
ENSMUST00000202217.3
septin 11
chr11_+_101137231 0.75 ENSMUST00000122006.8
ENSMUST00000151830.2
receptor (calcitonin) activity modifying protein 2
chr10_-_93146825 0.73 ENSMUST00000151153.2
ELK3, member of ETS oncogene family
chr16_-_85599994 0.72 ENSMUST00000023610.15
a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 1
chr6_-_84564623 0.71 ENSMUST00000205228.3
cytochrome P450, family 26, subfamily b, polypeptide 1
chr6_+_17463925 0.71 ENSMUST00000115442.8
met proto-oncogene
chr2_-_35994072 0.70 ENSMUST00000112961.10
ENSMUST00000112966.10
LIM homeobox protein 6
chr2_+_157401998 0.70 ENSMUST00000153739.9
ENSMUST00000173595.2
ENSMUST00000109526.2
ENSMUST00000173839.2
ENSMUST00000173041.8
ENSMUST00000173793.8
ENSMUST00000172487.2
ENSMUST00000088484.6
neuronatin
chr10_-_93146937 0.69 ENSMUST00000008542.12
ELK3, member of ETS oncogene family
chr15_-_89263790 0.67 ENSMUST00000238996.2
outer dense fiber of sperm tails 3B
chr9_-_110572721 0.66 ENSMUST00000166716.8
parathyroid hormone 1 receptor
chr11_-_100830288 0.66 ENSMUST00000138438.2
signal transducer and activator of transcription 3
chr16_-_46317318 0.65 ENSMUST00000023335.13
ENSMUST00000023334.15
nectin cell adhesion molecule 3
chrX_+_7439839 0.64 ENSMUST00000144719.9
ENSMUST00000234896.2
Foxp3 regulating long intergenic noncoding RNA
forkhead box P3
chr6_-_142647985 0.64 ENSMUST00000205202.3
ENSMUST00000073173.12
ENSMUST00000111771.8
ATP-binding cassette, sub-family C (CFTR/MRP), member 9
chr6_+_86172196 0.63 ENSMUST00000032066.13
transforming growth factor alpha
chr7_+_127846121 0.63 ENSMUST00000167965.8
transforming growth factor beta 1 induced transcript 1
chr10_-_43934774 0.62 ENSMUST00000239010.2
crystallin beta-gamma domain containing 1
chr4_+_45848664 0.61 ENSMUST00000107783.8
STRA6-like
chr17_-_66079681 0.60 ENSMUST00000070673.9
RAB31, member RAS oncogene family
chr1_-_151965876 0.60 ENSMUST00000044581.14
RIKEN cDNA 1700025G04 gene
chr15_-_89263128 0.60 ENSMUST00000227834.2
outer dense fiber of sperm tails 3B
chr11_-_100830183 0.60 ENSMUST00000092671.12
ENSMUST00000103114.8
signal transducer and activator of transcription 3
chrX_+_100427331 0.59 ENSMUST00000119190.2
gap junction protein, beta 1
chr9_+_44966464 0.58 ENSMUST00000114664.8
myelin protein zero-like 3
chr11_+_4085164 0.58 ENSMUST00000003677.11
ENSMUST00000145705.8
ring finger protein 215
chr17_-_85097945 0.58 ENSMUST00000112308.9
leucine-rich PPR-motif containing
chr7_-_126074222 0.58 ENSMUST00000205497.2
SH2B adaptor protein 1
chr6_-_142647944 0.58 ENSMUST00000100827.5
ENSMUST00000087527.11
ATP-binding cassette, sub-family C (CFTR/MRP), member 9
chr4_+_45848918 0.57 ENSMUST00000030011.6
STRA6-like
chr11_-_78136767 0.57 ENSMUST00000002121.5
SPT6, histone chaperone and transcription elongation factor
chr13_-_36918424 0.57 ENSMUST00000037623.15
neuritin 1
chr7_-_111379170 0.57 ENSMUST00000049430.15
ENSMUST00000106663.2
polypeptide N-acetylgalactosaminyltransferase 18
chr1_-_75482975 0.56 ENSMUST00000113567.10
ENSMUST00000113565.3
obscurin-like 1
chr4_+_45848816 0.56 ENSMUST00000107782.8
STRA6-like
chr5_+_117457356 0.56 ENSMUST00000086464.8
V-set and immunoglobulin domain containing 10
chr7_+_127845984 0.56 ENSMUST00000164710.8
ENSMUST00000070656.12
transforming growth factor beta 1 induced transcript 1
chr11_-_100830366 0.55 ENSMUST00000127638.8
signal transducer and activator of transcription 3
chr15_-_89024824 0.55 ENSMUST00000088827.8
mitogen-activated protein kinase 12
chr9_-_44646487 0.55 ENSMUST00000034611.15
pleckstrin homology like domain, family B, member 1
chr5_-_5564730 0.54 ENSMUST00000115445.8
ENSMUST00000179804.8
ENSMUST00000125110.2
ENSMUST00000115446.8
claudin 12
chr6_+_48372520 0.54 ENSMUST00000114571.8
ENSMUST00000031815.12
ENSMUST00000203371.3
KRAB-A domain containing 1
chr19_+_6434416 0.53 ENSMUST00000035269.15
ENSMUST00000113483.2
muscle glycogen phosphorylase
chr2_-_160714473 0.53 ENSMUST00000103111.9
zinc fingers and homeoboxes 3
chr9_-_110572694 0.53 ENSMUST00000196057.2
parathyroid hormone 1 receptor
chr1_+_75336965 0.53 ENSMUST00000027409.10
desmin
chr7_+_127728712 0.52 ENSMUST00000033053.8
ENSMUST00000205460.2
integrin alpha X
chr7_-_126483851 0.52 ENSMUST00000071268.11
ENSMUST00000117394.2
TAO kinase 2
chr8_+_127790772 0.51 ENSMUST00000079777.12
ENSMUST00000160272.8
ENSMUST00000162907.8
ENSMUST00000162536.8
ENSMUST00000026921.13
ENSMUST00000162665.8
ENSMUST00000162602.8
ENSMUST00000160581.8
ENSMUST00000161355.8
ENSMUST00000162531.8
ENSMUST00000160766.8
ENSMUST00000159537.8
par-3 family cell polarity regulator
chr9_-_58065800 0.51 ENSMUST00000168864.4
immunoglobulin superfamily containing leucine-rich repeat
chr4_+_116953218 0.51 ENSMUST00000030443.12
patched 2
chr15_-_89263448 0.50 ENSMUST00000049968.9
outer dense fiber of sperm tails 3B
chrX_-_149595873 0.50 ENSMUST00000131241.2
ENSMUST00000147152.3
ENSMUST00000143843.8
MAGE family member D2
chr3_-_101017594 0.49 ENSMUST00000102694.4
prostaglandin F2 receptor negative regulator
chr16_-_46317135 0.49 ENSMUST00000149901.2
ENSMUST00000096052.9
nectin cell adhesion molecule 3
chr1_-_153061758 0.49 ENSMUST00000185356.7
laminin, gamma 2
chr4_-_150039486 0.49 ENSMUST00000038562.9
splA/ryanodine receptor domain and SOCS box containing 1
chr3_+_28038283 0.47 ENSMUST00000067757.11
ENSMUST00000123539.8
phospholipase D1
chr2_-_35995283 0.47 ENSMUST00000112960.8
ENSMUST00000112967.12
ENSMUST00000112963.8
LIM homeobox protein 6
chr11_-_35871300 0.47 ENSMUST00000018993.7
WW, C2 and coiled-coil domain containing 1
chr4_+_15265798 0.47 ENSMUST00000062684.9
transmembrane protein 64
chr9_-_50663648 0.47 ENSMUST00000217159.2
heat shock protein 2
chr17_-_13070780 0.47 ENSMUST00000162389.2
ENSMUST00000162119.8
ENSMUST00000159223.8
MAS1 oncogene
chr11_-_70120503 0.46 ENSMUST00000153449.2
ENSMUST00000000326.12
B cell CLL/lymphoma 6, member B
chr10_+_40505985 0.46 ENSMUST00000019977.8
ENSMUST00000214102.2
ENSMUST00000213503.2
ENSMUST00000213442.2
ENSMUST00000216830.2
D-aspartate oxidase
chr16_+_91066602 0.46 ENSMUST00000056882.7
oligodendrocyte transcription factor 1
chrX_-_149595711 0.45 ENSMUST00000112697.10
MAGE family member D2
chr6_-_84564972 0.45 ENSMUST00000204109.2
cytochrome P450, family 26, subfamily b, polypeptide 1
chr8_+_107662352 0.45 ENSMUST00000212524.2
ENSMUST00000047425.5
syntrophin, basic 2
chr13_+_54519161 0.44 ENSMUST00000026985.9
complexin 2
chr5_-_5564873 0.44 ENSMUST00000060947.14
claudin 12
chr11_-_30218167 0.44 ENSMUST00000006629.14
spectrin beta, non-erythrocytic 1
chr5_-_24935633 0.42 ENSMUST00000068693.12
WD repeat domain 86
chr9_-_106315368 0.42 ENSMUST00000190900.2
ENSMUST00000214275.2
aminoacylase 1
chr16_-_85347305 0.41 ENSMUST00000175700.8
ENSMUST00000114174.3
cysteine and tyrosine-rich protein 1
chr13_-_9815350 0.41 ENSMUST00000110636.9
ENSMUST00000152725.8
zinc finger, MYND domain containing 11
chr5_+_115644727 0.41 ENSMUST00000067268.15
ENSMUST00000086523.7
ENSMUST00000212819.3
paxillin
chr13_-_9815173 0.41 ENSMUST00000062658.15
ENSMUST00000222358.2
zinc finger, MYND domain containing 11
chr6_+_17491231 0.41 ENSMUST00000080469.12
met proto-oncogene
chr17_+_15230438 0.41 ENSMUST00000097395.5
predicted gene 3435
chr11_+_77654072 0.40 ENSMUST00000108375.9
myosin XVIIIA
chr17_+_56633040 0.40 ENSMUST00000139679.8
ENSMUST00000025036.11
ENSMUST00000086835.12
lysine (K)-specific demethylase 4B
chr19_+_5524933 0.40 ENSMUST00000236518.2
epidermal growth factor-containing fibulin-like extracellular matrix protein 2
chr17_+_15261896 0.40 ENSMUST00000226599.2
ENSMUST00000228518.2
ENSMUST00000226213.2
ER membrane associated RNA degradation
chr2_+_70305267 0.40 ENSMUST00000100043.3
trans-acting transcription factor 5
chr4_+_106418224 0.39 ENSMUST00000047973.4
24-dehydrocholesterol reductase
chr4_-_4138432 0.39 ENSMUST00000070375.8
preproenkephalin
chr2_+_26969384 0.39 ENSMUST00000091233.7
ADAMTS-like 2
chr8_-_41494890 0.38 ENSMUST00000051379.14
mitochondrial tumor suppressor 1
chr13_+_54722823 0.38 ENSMUST00000026988.11
ADP-ribosylation factor-like 10
chr17_-_24869241 0.38 ENSMUST00000234557.2
ENSMUST00000002572.6
solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 2
chr3_+_115801106 0.38 ENSMUST00000029575.12
ENSMUST00000106501.8
exostosin-like glycosyltransferase 2
chr9_+_50664288 0.38 ENSMUST00000214962.2
ENSMUST00000216755.2
crystallin, alpha B
chr3_-_95811993 0.37 ENSMUST00000147962.3
ENSMUST00000036181.15
carbonic anhydrase 14
chr7_+_127078371 0.37 ENSMUST00000205432.3
fibrosin
chr4_-_70453140 0.37 ENSMUST00000107359.9
multiple EGF-like-domains 9
chr17_+_34406523 0.37 ENSMUST00000170086.8
transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
chr9_+_50664207 0.36 ENSMUST00000034562.9
crystallin, alpha B
chr11_+_69656797 0.36 ENSMUST00000108642.8
ENSMUST00000156932.8
zinc finger and BTB domain containing 4
chr13_-_9814979 0.36 ENSMUST00000110634.8
zinc finger, MYND domain containing 11
chr11_-_118139331 0.36 ENSMUST00000017276.14
cytohesin 1
chr16_-_17711950 0.36 ENSMUST00000155943.9
DiGeorge syndrome critical region gene 2
chr2_-_181234526 0.35 ENSMUST00000108789.9
ENSMUST00000153998.2
zinc finger protein 512B
chr16_+_18595589 0.35 ENSMUST00000043577.3
claudin 5
chr8_-_34614187 0.35 ENSMUST00000033910.9
leptin receptor overlapping transcript-like 1
chr11_+_70538083 0.34 ENSMUST00000037534.8
ring finger protein 167
chr17_+_35113490 0.34 ENSMUST00000052778.10
zinc finger and BTB domain containing 12
chr13_+_55097200 0.34 ENSMUST00000026994.14
ENSMUST00000109994.9
unc-5 netrin receptor A
chr4_+_42949814 0.34 ENSMUST00000037872.10
ENSMUST00000098112.9
DnaJ heat shock protein family (Hsp40) member B5
chr12_-_80483343 0.33 ENSMUST00000054145.8
DDB1 and CUL4 associated factor 5
chr2_+_119378178 0.33 ENSMUST00000014221.13
ENSMUST00000119172.2
calcineurin-like EF hand protein 1
chr17_+_34406762 0.32 ENSMUST00000041633.15
transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
chr11_-_118139418 0.32 ENSMUST00000106305.9
cytohesin 1
chr11_-_69260203 0.32 ENSMUST00000092971.13
ENSMUST00000108661.8
chromodomain helicase DNA binding protein 3
chr1_+_153776323 0.32 ENSMUST00000140685.4
ENSMUST00000139476.8
glutamate-ammonia ligase (glutamine synthetase)
chr7_+_12615091 0.31 ENSMUST00000144578.2
zinc finger protein 128
chr11_+_101066867 0.31 ENSMUST00000103109.4
contactin associated protein-like 1
chr10_-_128640232 0.31 ENSMUST00000051011.14
transmembrane protein 198b
chr16_-_30369378 0.31 ENSMUST00000140402.8
transmembrane protein 44
chr11_-_118139312 0.31 ENSMUST00000100181.11
cytohesin 1
chr11_-_120440519 0.31 ENSMUST00000034913.5
MAPK regulated corepressor interacting protein 1
chr11_+_95734419 0.30 ENSMUST00000107708.2
guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 2
chr11_+_115921129 0.30 ENSMUST00000021116.12
ENSMUST00000106452.2
unkempt family zinc finger
chr10_-_115151451 0.30 ENSMUST00000020343.9
ENSMUST00000218831.2
RAB21, member RAS oncogene family
chrX_+_73372664 0.30 ENSMUST00000004326.4
plexin A3
chr7_-_44702269 0.29 ENSMUST00000057293.8
proline rich 12
chr3_-_115800989 0.28 ENSMUST00000067485.4
solute carrier family 30 (zinc transporter), member 7
chr5_-_125135434 0.28 ENSMUST00000134404.6
ENSMUST00000199561.2
nuclear receptor co-repressor 2
chr5_-_142803405 0.28 ENSMUST00000151477.8
trinucleotide repeat containing 18
chr11_+_78136569 0.28 ENSMUST00000002133.9
stromal cell derived factor 2
chr4_+_12140263 0.28 ENSMUST00000050069.9
ENSMUST00000069128.8
RNA binding motif protein 12 B1
chr15_-_99717956 0.28 ENSMUST00000109024.9
LIM domain and actin binding 1
chr17_-_24424456 0.28 ENSMUST00000201583.2
ENSMUST00000202925.4
ENSMUST00000167791.9
ENSMUST00000201960.4
ENSMUST00000040474.11
ENSMUST00000201089.4
ENSMUST00000201301.4
ENSMUST00000201805.4
ENSMUST00000168410.9
ENSMUST00000097376.10
TBC1 domain family, member 24
chr10_+_128542120 0.28 ENSMUST00000054125.9
premelanosome protein
chr17_+_35354172 0.27 ENSMUST00000172571.8
ENSMUST00000173491.8
BCL2-associated athanogene 6

Network of associatons between targets according to the STRING database.

First level regulatory network of Gli3_Zic1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 4.0 GO:0006571 tyrosine biosynthetic process(GO:0006571) aromatic amino acid family biosynthetic process(GO:0009073) aromatic amino acid family biosynthetic process, prephenate pathway(GO:0009095)
0.8 2.4 GO:0042323 regulation of nucleoside transport(GO:0032242) negative regulation of circadian sleep/wake cycle, non-REM sleep(GO:0042323) negative regulation of mucus secretion(GO:0070256)
0.7 3.3 GO:0048807 female genitalia morphogenesis(GO:0048807)
0.6 1.7 GO:0071938 vitamin A transport(GO:0071938) vitamin A import(GO:0071939)
0.6 1.7 GO:0071874 smooth endoplasmic reticulum calcium ion homeostasis(GO:0051563) cellular response to norepinephrine stimulus(GO:0071874)
0.5 6.2 GO:2000467 positive regulation of glycogen (starch) synthase activity(GO:2000467)
0.4 1.2 GO:2000847 negative regulation of corticosteroid hormone secretion(GO:2000847) negative regulation of glucocorticoid secretion(GO:2000850)
0.4 2.4 GO:0030421 defecation(GO:0030421)
0.4 1.5 GO:0009436 glyoxylate catabolic process(GO:0009436)
0.4 2.2 GO:0072014 proximal tubule development(GO:0072014)
0.4 1.8 GO:1902728 positive regulation of skeletal muscle satellite cell proliferation(GO:1902724) positive regulation of growth factor dependent skeletal muscle satellite cell proliferation(GO:1902728)
0.3 2.3 GO:0055095 lipoprotein particle mediated signaling(GO:0055095) low-density lipoprotein particle mediated signaling(GO:0055096)
0.3 2.2 GO:0009750 response to fructose(GO:0009750)
0.3 0.9 GO:1904954 canonical Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation(GO:1904954)
0.3 0.9 GO:0030070 insulin processing(GO:0030070)
0.2 2.4 GO:0042760 very long-chain fatty acid catabolic process(GO:0042760)
0.2 0.7 GO:0046967 cytosol to ER transport(GO:0046967)
0.2 0.9 GO:1902269 positive regulation of polyamine transmembrane transport(GO:1902269)
0.2 0.6 GO:0002851 positive regulation of tolerance induction dependent upon immune response(GO:0002654) regulation of peripheral tolerance induction(GO:0002658) positive regulation of peripheral tolerance induction(GO:0002660) regulation of peripheral T cell tolerance induction(GO:0002849) positive regulation of peripheral T cell tolerance induction(GO:0002851)
0.2 1.9 GO:0015671 oxygen transport(GO:0015671)
0.2 6.1 GO:0043567 regulation of insulin-like growth factor receptor signaling pathway(GO:0043567)
0.2 1.2 GO:1902811 tongue muscle cell differentiation(GO:0035981) positive regulation of skeletal muscle fiber differentiation(GO:1902811) regulation of tongue muscle cell differentiation(GO:2001035) positive regulation of tongue muscle cell differentiation(GO:2001037)
0.2 1.2 GO:1904936 cerebral cortex GABAergic interneuron migration(GO:0021853) interneuron migration(GO:1904936)
0.2 1.1 GO:0070495 regulation of thrombin receptor signaling pathway(GO:0070494) negative regulation of thrombin receptor signaling pathway(GO:0070495)
0.2 0.5 GO:0044339 canonical Wnt signaling pathway involved in osteoblast differentiation(GO:0044339)
0.2 0.5 GO:0006533 aspartate catabolic process(GO:0006533)
0.1 0.9 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
0.1 0.6 GO:0000957 mitochondrial RNA catabolic process(GO:0000957) regulation of mitochondrial RNA catabolic process(GO:0000960)
0.1 1.6 GO:0007021 tubulin complex assembly(GO:0007021)
0.1 1.7 GO:0019367 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.1 0.4 GO:1903028 regulation of opsonization(GO:1903027) positive regulation of opsonization(GO:1903028)
0.1 0.3 GO:0010726 positive regulation of hydrogen peroxide metabolic process(GO:0010726)
0.1 1.2 GO:0030579 ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.1 0.8 GO:0097167 circadian regulation of translation(GO:0097167) negative regulation of glucocorticoid receptor signaling pathway(GO:2000323)
0.1 0.9 GO:0070294 renal sodium ion absorption(GO:0070294)
0.1 2.0 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.1 0.2 GO:0097017 renal protein absorption(GO:0097017)
0.1 0.9 GO:0036506 maintenance of unfolded protein(GO:0036506) maintenance of unfolded protein involved in ERAD pathway(GO:1904378)
0.1 0.6 GO:0061086 negative regulation of histone H3-K27 methylation(GO:0061086)
0.1 0.3 GO:0070194 synaptonemal complex disassembly(GO:0070194)
0.1 0.2 GO:0070671 response to interleukin-12(GO:0070671)
0.1 0.3 GO:0006542 glutamine biosynthetic process(GO:0006542)
0.1 2.5 GO:0021692 cerebellar Purkinje cell layer morphogenesis(GO:0021692)
0.1 1.5 GO:0060732 positive regulation of inositol phosphate biosynthetic process(GO:0060732)
0.1 3.4 GO:0000731 DNA synthesis involved in DNA repair(GO:0000731)
0.1 0.6 GO:0003383 apical constriction(GO:0003383)
0.1 0.4 GO:1904953 Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation(GO:1904953)
0.1 0.3 GO:0010615 positive regulation of cardiac muscle adaptation(GO:0010615) positive regulation of cardiac muscle hypertrophy in response to stress(GO:1903244)
0.1 0.9 GO:2000860 positive regulation of mineralocorticoid secretion(GO:2000857) positive regulation of aldosterone secretion(GO:2000860)
0.1 0.7 GO:0097646 calcitonin family receptor signaling pathway(GO:0097646) amylin receptor signaling pathway(GO:0097647)
0.1 0.3 GO:0032417 positive regulation of sodium:proton antiporter activity(GO:0032417)
0.1 0.5 GO:0035331 negative regulation of hippo signaling(GO:0035331)
0.1 0.2 GO:0060010 Sertoli cell fate commitment(GO:0060010)
0.1 0.2 GO:1904742 regulation of telomeric DNA binding(GO:1904742)
0.1 1.6 GO:0006309 apoptotic DNA fragmentation(GO:0006309)
0.1 0.3 GO:0072365 regulation of cellular ketone metabolic process by negative regulation of transcription from RNA polymerase II promoter(GO:0072365)
0.1 0.3 GO:1905035 regulation of antifungal innate immune response(GO:1905034) negative regulation of antifungal innate immune response(GO:1905035)
0.1 0.4 GO:0019276 UDP-N-acetylgalactosamine metabolic process(GO:0019276)
0.1 0.2 GO:0060167 regulation of adenosine receptor signaling pathway(GO:0060167) positive regulation of adenosine receptor signaling pathway(GO:0060168) regulation of G-protein coupled receptor internalization(GO:1904020)
0.1 0.2 GO:0046061 dATP catabolic process(GO:0046061)
0.1 0.1 GO:0071288 cellular response to mercury ion(GO:0071288)
0.1 0.2 GO:0014022 neural plate elongation(GO:0014022) convergent extension involved in neural plate elongation(GO:0022007)
0.1 1.1 GO:1902414 protein localization to cell junction(GO:1902414)
0.1 0.6 GO:0007525 somatic muscle development(GO:0007525)
0.1 1.2 GO:0051481 negative regulation of cytosolic calcium ion concentration(GO:0051481)
0.1 0.6 GO:0015868 purine ribonucleotide transport(GO:0015868)
0.1 1.5 GO:0005980 glycogen catabolic process(GO:0005980) glucan catabolic process(GO:0009251) cellular polysaccharide catabolic process(GO:0044247)
0.1 0.3 GO:0014886 transition between slow and fast fiber(GO:0014886)
0.0 0.3 GO:0032511 late endosome to vacuole transport via multivesicular body sorting pathway(GO:0032511)
0.0 0.2 GO:0061534 gamma-aminobutyric acid secretion, neurotransmission(GO:0061534)
0.0 0.3 GO:0060296 regulation of cilium movement involved in cell motility(GO:0060295) regulation of cilium beat frequency involved in ciliary motility(GO:0060296) regulation of cilium-dependent cell motility(GO:1902019)
0.0 0.2 GO:0002018 renin-angiotensin regulation of aldosterone production(GO:0002018)
0.0 1.3 GO:0045603 positive regulation of endothelial cell differentiation(GO:0045603)
0.0 1.1 GO:0033539 fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
0.0 0.7 GO:0001542 ovulation from ovarian follicle(GO:0001542)
0.0 0.4 GO:0007182 common-partner SMAD protein phosphorylation(GO:0007182)
0.0 0.3 GO:0010961 cellular magnesium ion homeostasis(GO:0010961)
0.0 0.9 GO:0090190 positive regulation of branching involved in ureteric bud morphogenesis(GO:0090190)
0.0 0.3 GO:1902287 trigeminal nerve morphogenesis(GO:0021636) trigeminal nerve structural organization(GO:0021637) semaphorin-plexin signaling pathway involved in axon guidance(GO:1902287)
0.0 0.8 GO:0070831 basement membrane assembly(GO:0070831)
0.0 0.1 GO:0010512 negative regulation of phosphatidylinositol biosynthetic process(GO:0010512)
0.0 0.2 GO:0017055 negative regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0017055)
0.0 0.1 GO:0001180 transcription initiation from RNA polymerase I promoter for nuclear large rRNA transcript(GO:0001180)
0.0 0.4 GO:0015669 gas transport(GO:0015669)
0.0 0.5 GO:0032534 regulation of microvillus assembly(GO:0032534)
0.0 0.6 GO:0071688 striated muscle myosin thick filament assembly(GO:0071688)
0.0 0.4 GO:1900113 negative regulation of histone H3-K9 trimethylation(GO:1900113)
0.0 2.2 GO:0045840 positive regulation of mitotic nuclear division(GO:0045840)
0.0 2.2 GO:0007528 neuromuscular junction development(GO:0007528)
0.0 0.3 GO:0033564 anterior/posterior axon guidance(GO:0033564)
0.0 0.4 GO:0031915 positive regulation of synaptic plasticity(GO:0031915)
0.0 0.3 GO:0040031 snRNA modification(GO:0040031)
0.0 0.3 GO:0002175 protein localization to paranode region of axon(GO:0002175)
0.0 0.4 GO:0007183 SMAD protein complex assembly(GO:0007183)
0.0 0.3 GO:2000766 negative regulation of cytoplasmic translation(GO:2000766)
0.0 0.3 GO:2000643 positive regulation of early endosome to late endosome transport(GO:2000643)
0.0 0.7 GO:0034389 lipid particle organization(GO:0034389)
0.0 1.0 GO:0090162 establishment of epithelial cell polarity(GO:0090162)
0.0 0.2 GO:1901509 regulation of endothelial tube morphogenesis(GO:1901509)
0.0 0.5 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.0 0.4 GO:2000987 positive regulation of fear response(GO:1903367) positive regulation of behavioral fear response(GO:2000987)
0.0 0.4 GO:0060481 lobar bronchus epithelium development(GO:0060481)
0.0 1.2 GO:0010107 potassium ion import(GO:0010107)
0.0 0.1 GO:0003221 right ventricular cardiac muscle tissue morphogenesis(GO:0003221)
0.0 0.2 GO:0021873 forebrain neuroblast division(GO:0021873)
0.0 0.2 GO:0030050 vesicle transport along actin filament(GO:0030050)
0.0 1.4 GO:0046329 negative regulation of JNK cascade(GO:0046329)
0.0 1.2 GO:0010883 regulation of lipid storage(GO:0010883)
0.0 0.3 GO:0071712 ER-associated misfolded protein catabolic process(GO:0071712)
0.0 0.1 GO:0010360 negative regulation of anion channel activity(GO:0010360)
0.0 0.3 GO:0046543 development of secondary female sexual characteristics(GO:0046543)
0.0 0.4 GO:0036342 post-anal tail morphogenesis(GO:0036342)
0.0 0.2 GO:0006689 ganglioside catabolic process(GO:0006689) oligosaccharide catabolic process(GO:0009313)
0.0 0.0 GO:0019046 release from viral latency(GO:0019046)
0.0 0.4 GO:0014067 negative regulation of phosphatidylinositol 3-kinase signaling(GO:0014067)
0.0 0.4 GO:0060396 growth hormone receptor signaling pathway(GO:0060396) cellular response to growth hormone stimulus(GO:0071378)
0.0 0.3 GO:0061088 sequestering of zinc ion(GO:0032119) regulation of sequestering of zinc ion(GO:0061088)
0.0 1.5 GO:0043407 negative regulation of MAP kinase activity(GO:0043407)
0.0 0.3 GO:0048023 positive regulation of melanin biosynthetic process(GO:0048023) positive regulation of secondary metabolite biosynthetic process(GO:1900378)
0.0 0.1 GO:2000812 regulation of barbed-end actin filament capping(GO:2000812)
0.0 0.2 GO:0070863 positive regulation of protein exit from endoplasmic reticulum(GO:0070863)
0.0 0.5 GO:0045109 intermediate filament organization(GO:0045109)
0.0 0.3 GO:0048681 negative regulation of axon regeneration(GO:0048681)
0.0 0.1 GO:0021914 negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning(GO:0021914)
0.0 0.2 GO:0090050 positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050)
0.0 0.2 GO:2001288 positive regulation of caveolin-mediated endocytosis(GO:2001288)
0.0 0.1 GO:0006703 estrogen biosynthetic process(GO:0006703)
0.0 0.4 GO:0030539 male genitalia development(GO:0030539)
0.0 0.1 GO:0045084 positive regulation of interleukin-12 biosynthetic process(GO:0045084)
0.0 0.3 GO:0043116 negative regulation of vascular permeability(GO:0043116)
0.0 0.1 GO:0001927 exocyst assembly(GO:0001927)
0.0 0.6 GO:0090382 phagosome maturation(GO:0090382)
0.0 0.2 GO:0043615 astrocyte cell migration(GO:0043615)
0.0 0.8 GO:0006635 fatty acid beta-oxidation(GO:0006635)
0.0 0.3 GO:0008272 sulfate transport(GO:0008272)
0.0 0.5 GO:0000186 activation of MAPKK activity(GO:0000186)
0.0 0.1 GO:0019348 dolichol metabolic process(GO:0019348)
0.0 0.0 GO:0032847 regulation of nitrogen utilization(GO:0006808) nitrogen utilization(GO:0019740) regulation of cellular pH reduction(GO:0032847)
0.0 0.1 GO:0009957 epidermal cell fate specification(GO:0009957)
0.0 0.2 GO:0051085 chaperone mediated protein folding requiring cofactor(GO:0051085)
0.0 0.3 GO:1900078 positive regulation of cellular response to insulin stimulus(GO:1900078)
0.0 0.1 GO:0090161 Golgi ribbon formation(GO:0090161)
0.0 0.3 GO:2001224 positive regulation of neuron migration(GO:2001224)
0.0 0.5 GO:0042092 type 2 immune response(GO:0042092)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 3.8 GO:0043625 delta DNA polymerase complex(GO:0043625)
0.4 1.7 GO:0097447 dendritic tree(GO:0097447)
0.4 2.9 GO:0008091 spectrin(GO:0008091)
0.2 0.5 GO:0005607 laminin-2 complex(GO:0005607)
0.2 1.7 GO:1990761 growth cone lamellipodium(GO:1990761) growth cone filopodium(GO:1990812)
0.1 1.2 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.1 5.0 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.1 0.7 GO:1903440 calcitonin family receptor complex(GO:1903439) amylin receptor complex(GO:1903440)
0.1 0.9 GO:0071818 BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
0.1 2.5 GO:0098984 neuron to neuron synapse(GO:0098984)
0.1 2.3 GO:0042627 chylomicron(GO:0042627)
0.1 0.4 GO:0070033 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex(GO:0070033)
0.1 0.9 GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.1 0.7 GO:0042825 TAP complex(GO:0042825)
0.1 0.6 GO:0033269 internode region of axon(GO:0033269)
0.1 0.3 GO:0098559 cytoplasmic side of early endosome membrane(GO:0098559)
0.0 0.2 GO:0043293 apoptosome(GO:0043293)
0.0 0.5 GO:0045098 type III intermediate filament(GO:0045098)
0.0 0.5 GO:0030478 actin cap(GO:0030478)
0.0 0.2 GO:0000308 cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308)
0.0 0.8 GO:0031045 dense core granule(GO:0031045)
0.0 0.3 GO:0005955 calcineurin complex(GO:0005955)
0.0 0.1 GO:0005668 RNA polymerase transcription factor SL1 complex(GO:0005668)
0.0 0.7 GO:0033270 paranode region of axon(GO:0033270)
0.0 0.4 GO:0072546 ER membrane protein complex(GO:0072546)
0.0 0.3 GO:0032585 multivesicular body membrane(GO:0032585)
0.0 0.4 GO:1990909 Wnt signalosome(GO:1990909)
0.0 0.3 GO:0072687 meiotic spindle(GO:0072687)
0.0 0.6 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.0 0.2 GO:0044214 spanning component of plasma membrane(GO:0044214) spanning component of membrane(GO:0089717)
0.0 2.4 GO:0005778 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.0 1.7 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 0.6 GO:0005922 connexon complex(GO:0005922)
0.0 0.2 GO:0000322 storage vacuole(GO:0000322)
0.0 0.1 GO:0033185 dolichol-phosphate-mannose synthase complex(GO:0033185)
0.0 0.6 GO:0005859 muscle myosin complex(GO:0005859)
0.0 0.1 GO:0031310 integral component of vacuolar membrane(GO:0031166) intrinsic component of vacuolar membrane(GO:0031310)
0.0 0.4 GO:0042641 actomyosin(GO:0042641)
0.0 0.3 GO:0045180 basal cortex(GO:0045180)
0.0 1.6 GO:0031594 neuromuscular junction(GO:0031594)
0.0 0.6 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.0 2.3 GO:0032432 actin filament bundle(GO:0032432)
0.0 1.1 GO:0030667 secretory granule membrane(GO:0030667)
0.0 0.7 GO:0009925 basal plasma membrane(GO:0009925)
0.0 0.1 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.0 0.3 GO:0097386 glial cell projection(GO:0097386)
0.0 0.3 GO:0090545 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.0 0.5 GO:0008305 integrin complex(GO:0008305)
0.0 0.8 GO:0016328 lateral plasma membrane(GO:0016328)
0.0 0.2 GO:0031011 Ino80 complex(GO:0031011)
0.0 4.1 GO:0016324 apical plasma membrane(GO:0016324)
0.0 0.6 GO:0005834 heterotrimeric G-protein complex(GO:0005834)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 3.6 GO:0034632 retinol transporter activity(GO:0034632)
0.7 2.2 GO:0035939 microsatellite binding(GO:0035939)
0.7 4.0 GO:0004505 phenylalanine 4-monooxygenase activity(GO:0004505)
0.6 6.1 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.5 1.9 GO:0004096 catalase activity(GO:0004096)
0.4 1.2 GO:0008281 sulfonylurea receptor activity(GO:0008281)
0.4 1.5 GO:0016833 oxo-acid-lyase activity(GO:0016833)
0.4 1.5 GO:0008184 glycogen phosphorylase activity(GO:0008184)
0.4 1.1 GO:0017099 very-long-chain-acyl-CoA dehydrogenase activity(GO:0017099)
0.4 1.4 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.3 1.1 GO:0005008 hepatocyte growth factor-activated receptor activity(GO:0005008)
0.3 2.4 GO:0032795 heterotrimeric G-protein binding(GO:0032795)
0.2 1.7 GO:0051425 PTB domain binding(GO:0051425)
0.2 0.7 GO:0046980 peptide antigen-transporting ATPase activity(GO:0015433) tapasin binding(GO:0046980)
0.2 2.2 GO:0070095 fructose-6-phosphate binding(GO:0070095)
0.2 0.9 GO:0042978 ornithine decarboxylase activator activity(GO:0042978)
0.2 1.2 GO:0048495 Roundabout binding(GO:0048495)
0.2 1.2 GO:0008401 retinoic acid 4-hydroxylase activity(GO:0008401)
0.2 1.3 GO:0004991 parathyroid hormone receptor activity(GO:0004991)
0.2 1.8 GO:0031730 CCR5 chemokine receptor binding(GO:0031730)
0.1 1.7 GO:0102337 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.1 6.2 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.1 0.4 GO:0001888 glucuronyl-galactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0001888)
0.1 0.4 GO:0010428 methyl-CpNpG binding(GO:0010428)
0.1 0.5 GO:0003884 D-amino-acid oxidase activity(GO:0003884)
0.1 7.5 GO:0008028 monocarboxylic acid transmembrane transporter activity(GO:0008028)
0.1 2.3 GO:0004806 triglyceride lipase activity(GO:0004806)
0.1 0.7 GO:0097643 amylin receptor activity(GO:0097643)
0.1 3.8 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.1 0.3 GO:0004356 glutamate-ammonia ligase activity(GO:0004356) ammonia ligase activity(GO:0016211)
0.1 0.4 GO:0051435 BH4 domain binding(GO:0051435)
0.1 0.4 GO:0050436 microfibril binding(GO:0050436)
0.1 0.2 GO:0052642 lysophosphatidic acid phosphatase activity(GO:0052642)
0.1 0.9 GO:0009881 photoreceptor activity(GO:0009881)
0.1 0.5 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.1 0.9 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.1 0.4 GO:0004046 aminoacylase activity(GO:0004046)
0.1 1.4 GO:0044548 S100 protein binding(GO:0044548)
0.1 0.8 GO:0004300 enoyl-CoA hydratase activity(GO:0004300)
0.1 1.7 GO:0005212 structural constituent of eye lens(GO:0005212)
0.1 0.5 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.1 0.5 GO:0001595 angiotensin receptor activity(GO:0001595)
0.1 0.2 GO:0045159 myosin II binding(GO:0045159)
0.1 0.6 GO:0000990 transcription factor activity, core RNA polymerase binding(GO:0000990)
0.1 0.2 GO:0004609 phosphatidylserine decarboxylase activity(GO:0004609)
0.1 0.4 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.0 0.4 GO:0001515 opioid peptide activity(GO:0001515)
0.0 0.2 GO:0031687 A2A adenosine receptor binding(GO:0031687)
0.0 2.0 GO:0043236 laminin binding(GO:0043236)
0.0 0.3 GO:0033192 calmodulin-dependent protein phosphatase activity(GO:0033192)
0.0 0.6 GO:0051525 NFAT protein binding(GO:0051525)
0.0 0.3 GO:0005042 netrin receptor activity(GO:0005042)
0.0 0.8 GO:0015643 toxic substance binding(GO:0015643)
0.0 0.2 GO:0030280 structural constituent of epidermis(GO:0030280)
0.0 0.2 GO:0002153 steroid receptor RNA activator RNA binding(GO:0002153)
0.0 0.3 GO:0045545 syndecan binding(GO:0045545)
0.0 0.6 GO:0005243 gap junction channel activity(GO:0005243)
0.0 0.8 GO:0048018 receptor agonist activity(GO:0048018)
0.0 0.2 GO:0016997 exo-alpha-sialidase activity(GO:0004308) alpha-sialidase activity(GO:0016997) exo-alpha-(2->3)-sialidase activity(GO:0052794) exo-alpha-(2->6)-sialidase activity(GO:0052795) exo-alpha-(2->8)-sialidase activity(GO:0052796)
0.0 0.6 GO:0097493 structural molecule activity conferring elasticity(GO:0097493)
0.0 0.2 GO:0089720 caspase binding(GO:0089720)
0.0 0.6 GO:0004707 MAP kinase activity(GO:0004707)
0.0 0.6 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0 0.3 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.0 0.3 GO:1990715 mRNA CDS binding(GO:1990715)
0.0 0.1 GO:0003857 3-hydroxyacyl-CoA dehydrogenase activity(GO:0003857)
0.0 0.3 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.0 1.0 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 0.3 GO:0017154 semaphorin receptor activity(GO:0017154)
0.0 0.4 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 0.4 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.0 0.2 GO:0047134 protein-disulfide reductase activity(GO:0047134)
0.0 0.2 GO:0043560 insulin receptor substrate binding(GO:0043560)
0.0 0.2 GO:0035014 phosphatidylinositol 3-kinase regulator activity(GO:0035014)
0.0 3.0 GO:0008083 growth factor activity(GO:0008083)
0.0 0.1 GO:0005119 smoothened binding(GO:0005119) hedgehog receptor activity(GO:0008158)
0.0 1.4 GO:0035064 methylated histone binding(GO:0035064)
0.0 0.3 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0 0.1 GO:0015168 glycerol transmembrane transporter activity(GO:0015168)
0.0 0.4 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 1.0 GO:0005158 insulin receptor binding(GO:0005158)
0.0 0.3 GO:0043008 ATP-dependent protein binding(GO:0043008)
0.0 1.5 GO:0035591 signaling adaptor activity(GO:0035591)
0.0 0.5 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 0.2 GO:0032554 purine deoxyribonucleotide binding(GO:0032554)
0.0 0.3 GO:0051861 glycolipid binding(GO:0051861)
0.0 0.3 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.0 0.5 GO:0005109 frizzled binding(GO:0005109)
0.0 0.9 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.0 0.4 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.0 0.1 GO:0004035 alkaline phosphatase activity(GO:0004035)
0.0 0.4 GO:0016628 oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor(GO:0016628)
0.0 0.6 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.0 0.8 GO:0070888 E-box binding(GO:0070888)
0.0 0.3 GO:0019870 potassium channel inhibitor activity(GO:0019870)
0.0 0.1 GO:0004045 aminoacyl-tRNA hydrolase activity(GO:0004045)
0.0 0.2 GO:0046703 natural killer cell lectin-like receptor binding(GO:0046703)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.8 ST STAT3 PATHWAY STAT3 Pathway
0.1 7.3 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.1 2.0 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.1 2.0 ST G ALPHA S PATHWAY G alpha s Pathway
0.1 2.4 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.0 0.5 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.0 1.4 PID GLYPICAN 1PATHWAY Glypican 1 network
0.0 0.6 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.0 0.6 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.0 0.9 PID ALK1 PATHWAY ALK1 signaling events
0.0 0.6 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway
0.0 2.8 PID TRKR PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.0 0.8 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 0.5 PID ARF6 DOWNSTREAM PATHWAY Arf6 downstream pathway
0.0 4.3 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 0.1 PID NFKAPPAB ATYPICAL PATHWAY Atypical NF-kappaB pathway
0.0 0.7 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway
0.0 0.5 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.0 0.5 PID ERBB1 RECEPTOR PROXIMAL PATHWAY EGF receptor (ErbB1) signaling pathway
0.0 0.9 PID ARF6 TRAFFICKING PATHWAY Arf6 trafficking events
0.0 0.5 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.0 0.3 PID RET PATHWAY Signaling events regulated by Ret tyrosine kinase
0.0 0.7 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 0.7 PID TGFBR PATHWAY TGF-beta receptor signaling
0.0 0.4 PID NETRIN PATHWAY Netrin-mediated signaling events
0.0 0.5 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.0 0.7 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 12.3 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.3 3.8 REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
0.1 2.0 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.1 1.7 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.1 1.8 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.1 2.4 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.1 2.3 REACTOME NUCLEOTIDE LIKE PURINERGIC RECEPTORS Genes involved in Nucleotide-like (purinergic) receptors
0.1 2.3 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.1 1.2 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.1 1.7 REACTOME ALPHA LINOLENIC ACID ALA METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.1 1.4 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.1 1.7 REACTOME PROLACTIN RECEPTOR SIGNALING Genes involved in Prolactin receptor signaling
0.1 1.2 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport
0.1 2.2 REACTOME REGULATION OF GLUCOKINASE BY GLUCOKINASE REGULATORY PROTEIN Genes involved in Regulation of Glucokinase by Glucokinase Regulatory Protein
0.1 0.8 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.0 1.2 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 0.8 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.0 2.7 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0 0.7 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.0 2.0 REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0 1.3 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.0 1.2 REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.0 0.6 REACTOME DSCAM INTERACTIONS Genes involved in DSCAM interactions
0.0 3.7 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 0.6 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.0 0.5 REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.0 2.9 REACTOME NCAM SIGNALING FOR NEURITE OUT GROWTH Genes involved in NCAM signaling for neurite out-growth
0.0 1.1 REACTOME SEMA4D IN SEMAPHORIN SIGNALING Genes involved in Sema4D in semaphorin signaling
0.0 0.7 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.0 0.3 REACTOME ERKS ARE INACTIVATED Genes involved in ERKs are inactivated
0.0 0.3 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.0 0.2 REACTOME P75NTR RECRUITS SIGNALLING COMPLEXES Genes involved in p75NTR recruits signalling complexes
0.0 0.2 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.0 0.4 REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
0.0 0.3 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.0 0.1 REACTOME ACTIVATION OF NF KAPPAB IN B CELLS Genes involved in Activation of NF-kappaB in B Cells
0.0 0.5 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA