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GSE58827: Dynamics of the Mouse Liver

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Results for Hand1

Z-value: 1.11

Motif logo

Transcription factors associated with Hand1

Gene Symbol Gene ID Gene Info
ENSMUSG00000037335.14 heart and neural crest derivatives expressed 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Hand1mm39_v1_chr11_-_57722830_577229730.573.2e-04Click!

Activity profile of Hand1 motif

Sorted Z-values of Hand1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr7_+_18618605 5.30 ENSMUST00000032573.8
peptidoglycan recognition protein 1
chr10_+_75404482 4.80 ENSMUST00000134503.8
ENSMUST00000125770.8
ENSMUST00000128886.8
ENSMUST00000151212.8
gamma-glutamyltransferase 1
chr10_+_127350820 3.77 ENSMUST00000035735.11
Ndufa4, mitochondrial complex associated like 2
chr4_-_60538151 3.67 ENSMUST00000098047.3
major urinary protein 10
chr4_-_60222580 3.57 ENSMUST00000095058.5
ENSMUST00000163931.8
major urinary protein 8
chr10_+_75404464 3.34 ENSMUST00000145928.8
ENSMUST00000131565.8
gamma-glutamyltransferase 1
chr2_-_120867529 3.30 ENSMUST00000102490.10
erythrocyte membrane protein band 4.2
chr4_-_61592331 3.30 ENSMUST00000098040.4
major urinary protein 18
chr7_+_142559375 3.30 ENSMUST00000075172.12
ENSMUST00000105923.8
tetraspanin 32
chr11_+_32226893 2.89 ENSMUST00000145569.2
hemoglobin X, alpha-like embryonic chain in Hba complex
chr4_-_60070411 2.83 ENSMUST00000079697.10
ENSMUST00000125282.2
ENSMUST00000166098.8
major urinary protein 7
chr14_-_54949596 2.66 ENSMUST00000064290.8
CCAAT/enhancer binding protein (C/EBP), epsilon
chr2_-_120867232 2.65 ENSMUST00000023987.6
erythrocyte membrane protein band 4.2
chr7_+_24069680 2.64 ENSMUST00000205428.2
ENSMUST00000171904.3
ENSMUST00000205626.2
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 4
chr7_+_142558783 2.61 ENSMUST00000009396.13
tetraspanin 32
chr4_-_60377932 2.53 ENSMUST00000107506.9
ENSMUST00000122381.8
ENSMUST00000118759.8
ENSMUST00000132829.3
major urinary protein 9
chr7_+_142558837 2.38 ENSMUST00000207211.2
tetraspanin 32
chr8_-_86091946 2.32 ENSMUST00000034133.14
myosin light chain kinase 3
chr4_-_60618357 2.30 ENSMUST00000084544.5
ENSMUST00000098046.10
major urinary protein 11
chr13_-_37233179 2.29 ENSMUST00000037491.11
coagulation factor XIII, A1 subunit
chr8_-_86091970 2.28 ENSMUST00000121972.8
myosin light chain kinase 3
chr15_+_79232137 2.08 ENSMUST00000163691.3
v-maf musculoaponeurotic fibrosarcoma oncogene family, protein F (avian)
chr5_-_124492734 2.07 ENSMUST00000031341.11
CDK2 (cyclin-dependent kinase 2)-associated protein 1
chr17_-_26314461 2.02 ENSMUST00000236128.2
ENSMUST00000025007.7
NME/NM23 nucleoside diphosphate kinase 4
chr4_+_114945905 1.95 ENSMUST00000171877.8
ENSMUST00000177647.8
ENSMUST00000106548.9
ENSMUST00000030488.3
PDZK1 interacting protein 1
chr1_-_131066004 1.95 ENSMUST00000016670.9
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
chr17_-_26314438 1.92 ENSMUST00000236547.2
NME/NM23 nucleoside diphosphate kinase 4
chr17_+_47906985 1.90 ENSMUST00000182539.8
cyclin D3
chr4_-_154110324 1.86 ENSMUST00000130175.8
ENSMUST00000182151.8
small integral membrane protein 1
chr7_+_16515265 1.84 ENSMUST00000108496.9
solute carrier family 1 (neutral amino acid transporter), member 5
chr1_+_91294133 1.79 ENSMUST00000086861.12
erythroferrone
chr6_-_60806810 1.69 ENSMUST00000163779.8
synuclein, alpha
chr6_-_60805873 1.69 ENSMUST00000114268.5
synuclein, alpha
chr15_+_79232591 1.68 ENSMUST00000229285.2
v-maf musculoaponeurotic fibrosarcoma oncogene family, protein F (avian)
chr13_+_21679387 1.60 ENSMUST00000104942.2
cDNA sequence AK157302
chr14_-_36832044 1.60 ENSMUST00000179488.3
RIKEN cDNA 2610528A11 gene
chr2_+_109522781 1.60 ENSMUST00000111050.10
brain derived neurotrophic factor
chr11_-_69838971 1.60 ENSMUST00000179298.3
ENSMUST00000018710.13
ENSMUST00000135437.3
ENSMUST00000141837.9
ENSMUST00000142500.8
solute carrier family 2 (facilitated glucose transporter), member 4
chr9_+_123195986 1.56 ENSMUST00000038863.9
ENSMUST00000216843.2
leucyl-tRNA synthetase, mitochondrial
chr17_+_28988354 1.53 ENSMUST00000233109.2
ENSMUST00000004986.14
mitogen-activated protein kinase 13
chr11_+_120653613 1.46 ENSMUST00000105046.4
high mobility group AT-hook 1B
chr15_-_81845050 1.44 ENSMUST00000071462.7
ENSMUST00000023112.12
phosphomannomutase 1
chr9_+_21176582 1.44 ENSMUST00000065005.5
autophagy related 4D, cysteine peptidase
chr17_+_28988271 1.43 ENSMUST00000233984.2
ENSMUST00000233460.2
mitogen-activated protein kinase 13
chr11_-_102815910 1.43 ENSMUST00000021311.10
kinesin family member 18B
chr1_+_134109888 1.40 ENSMUST00000156873.8
chitinase-like 1
chr7_-_141241632 1.40 ENSMUST00000239500.1
mucin 6, gastric
chr11_+_97306353 1.39 ENSMUST00000121799.8
Rho GTPase activating protein 23
chr15_+_79982033 1.38 ENSMUST00000143928.2
synaptogyrin 1
chr8_+_85449632 1.35 ENSMUST00000098571.5
RIKEN cDNA G430095P16 gene
chr4_+_109533753 1.33 ENSMUST00000102724.5
Fas-associated factor 1
chr17_+_56347424 1.33 ENSMUST00000002914.10
chromatin assembly factor 1, subunit A (p150)
chr17_+_48761916 1.23 ENSMUST00000074574.13
unc-5 family C-terminal like
chr4_-_43499608 1.23 ENSMUST00000136005.3
ENSMUST00000054538.13
Rho guanine nucleotide exchange factor (GEF) 39
chr10_-_128237087 1.19 ENSMUST00000042666.13
solute carrier family 39 (metal ion transporter), member 5
chr4_+_120896582 1.19 ENSMUST00000030372.6
collagen, type IX, alpha 2
chr18_-_74340885 1.18 ENSMUST00000177604.2
spindle and kinetochore associated complex subunit 1
chr8_-_65489834 1.18 ENSMUST00000142822.4
apelin receptor early endogenous ligand
chr6_-_126916487 1.16 ENSMUST00000144954.5
ENSMUST00000112220.8
ENSMUST00000112221.8
RAD51 associated protein 1
chr7_-_4728081 1.15 ENSMUST00000086363.5
ENSMUST00000086364.11
transmembrane protein 150B
chr5_-_77457895 1.15 ENSMUST00000047860.9
nitric oxide associated 1
chr2_-_32271921 1.14 ENSMUST00000048792.5
RIKEN cDNA 1110008P14 gene
chr11_+_69805005 1.14 ENSMUST00000057884.6
G protein pathway suppressor 2
chr15_-_81845019 1.12 ENSMUST00000230229.2
phosphomannomutase 1
chr8_+_57964921 1.12 ENSMUST00000067925.8
high mobility group box 2
chr18_-_74340842 1.10 ENSMUST00000040188.16
spindle and kinetochore associated complex subunit 1
chr11_+_4186391 1.09 ENSMUST00000075221.3
oncostatin M
chr3_+_96069271 1.09 ENSMUST00000054356.16
myotubularin related protein 11
chr17_-_74602469 1.08 ENSMUST00000233144.2
mediator of cell motility 1
chr7_-_30738471 1.05 ENSMUST00000162250.8
FXYD domain-containing ion transport regulator 5
chr7_+_28488380 1.04 ENSMUST00000209035.2
ENSMUST00000059857.8
Ras and Rab interactor-like
chr11_-_3454766 1.04 ENSMUST00000044507.12
inositol polyphosphate 5-phosphatase J
chr17_+_33774681 1.02 ENSMUST00000087605.13
ENSMUST00000174695.2
myosin IF
chr9_+_106083988 1.00 ENSMUST00000188650.2
twinfilin actin binding protein 2
chr7_+_130633776 0.99 ENSMUST00000084509.7
ENSMUST00000213064.3
ENSMUST00000208311.4
deleted in malignant brain tumors 1
chr8_-_65489791 0.98 ENSMUST00000124790.8
apelin receptor early endogenous ligand
chr1_-_120197979 0.98 ENSMUST00000112639.8
STEAP family member 3
chr5_-_138170644 0.98 ENSMUST00000000505.16
minichromosome maintenance complex component 7
chr19_-_3979723 0.98 ENSMUST00000051803.8
aldehyde dehydrogenase 3 family, member B1
chr12_-_91712783 0.97 ENSMUST00000166967.2
stonin 2
chr10_+_80662490 0.96 ENSMUST00000060987.15
ENSMUST00000177850.8
ENSMUST00000180036.8
ENSMUST00000179172.8
ornithine decarboxylase antizyme 1
chr14_-_79718890 0.95 ENSMUST00000022601.7
WW domain binding protein 4
chr8_-_89362745 0.94 ENSMUST00000034087.9
sorting nexin 20
chr8_+_57964956 0.93 ENSMUST00000210871.2
high mobility group box 2
chr13_-_115226666 0.93 ENSMUST00000109226.5
pelota mRNA surveillance and ribosome rescue factor
chr2_+_132528851 0.92 ENSMUST00000061891.11
shieldin complex subunit 1
chr5_-_113968483 0.92 ENSMUST00000100874.6
selectin, platelet (p-selectin) ligand
chr5_+_35156389 0.88 ENSMUST00000114281.8
ENSMUST00000114280.8
regulator of G-protein signaling 12
chr4_-_117740624 0.87 ENSMUST00000030266.12
UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 2
chr4_-_45084564 0.87 ENSMUST00000052236.13
F-box protein 10
chr18_+_67476664 0.86 ENSMUST00000025404.10
cell death-inducing DNA fragmentation factor, alpha subunit-like effector A
chr3_-_90297187 0.83 ENSMUST00000029541.12
solute carrier family 27 (fatty acid transporter), member 3
chr1_-_192883642 0.80 ENSMUST00000192020.6
TRAF3 interacting protein 3
chr7_-_127593003 0.80 ENSMUST00000033056.5
PYD and CARD domain containing
chr19_-_4213347 0.79 ENSMUST00000025749.15
ribosomal protein S6 kinase, polypeptide 2
chr1_-_192880260 0.79 ENSMUST00000161367.2
TRAF3 interacting protein 3
chr7_-_30144933 0.79 ENSMUST00000006828.9
amyloid beta (A4) precursor-like protein 1
chr6_-_41613322 0.79 ENSMUST00000031902.7
transient receptor potential cation channel, subfamily V, member 6
chr4_+_119494901 0.78 ENSMUST00000024015.3
guanylate cyclase activator 2a (guanylin)
chr19_-_42074777 0.78 ENSMUST00000051772.10
MORN repeat containing 4
chr1_-_192883743 0.78 ENSMUST00000043550.11
TRAF3 interacting protein 3
chr1_+_163889713 0.77 ENSMUST00000097491.10
selectin, lymphocyte
chr8_-_106553822 0.77 ENSMUST00000239468.2
ENSMUST00000041400.6
RAN binding protein 10
chr9_+_53678801 0.75 ENSMUST00000048670.10
solute carrier family 35, member F2
chr14_-_51295099 0.75 ENSMUST00000227764.2
ribonuclease, RNase A family, 12 (non-active)
chr11_-_58829738 0.74 ENSMUST00000094151.6
ring finger protein 187
chr7_-_141614758 0.74 ENSMUST00000211000.2
ENSMUST00000209725.2
ENSMUST00000084418.4
MOB kinase activator 2
chr19_-_6178171 0.73 ENSMUST00000154601.8
ENSMUST00000138931.3
sorting nexin 15
chr15_+_97990431 0.71 ENSMUST00000229280.2
ENSMUST00000163507.8
ENSMUST00000230445.2
phosphofructokinase, muscle
chr2_-_32271833 0.70 ENSMUST00000146423.2
RIKEN cDNA 1110008P14 gene
chr14_+_54713557 0.70 ENSMUST00000164766.8
rad and gem related GTP binding protein 2
chr4_+_130640436 0.68 ENSMUST00000151698.8
lysosomal-associated protein transmembrane 5
chr12_-_4283926 0.68 ENSMUST00000111169.10
ENSMUST00000020981.12
centromere protein O
chr13_+_21364330 0.68 ENSMUST00000223065.2
tripartite motif-containing 27
chr2_-_126460575 0.67 ENSMUST00000028838.5
histidine decarboxylase
chr4_+_134847949 0.67 ENSMUST00000056977.14
runt related transcription factor 3
chr5_-_138170077 0.67 ENSMUST00000155902.8
ENSMUST00000148879.8
minichromosome maintenance complex component 7
chr5_-_124490296 0.66 ENSMUST00000111472.6
CDK2 (cyclin-dependent kinase 2)-associated protein 1
chr2_+_14878480 0.66 ENSMUST00000114719.7
calcium channel, voltage-dependent, beta 2 subunit
chr11_-_114825089 0.66 ENSMUST00000149663.4
ENSMUST00000239005.2
ENSMUST00000106581.5
CD300 molecule like family member B
chr8_-_108151661 0.65 ENSMUST00000003946.9
NIN1/RPN12 binding protein 1 homolog
chr2_+_110427643 0.65 ENSMUST00000045972.13
ENSMUST00000111026.3
solute carrier family 5 (sodium/glucose cotransporter), member 12
chrX_-_74174608 0.65 ENSMUST00000033775.9
membrane protein, palmitoylated
chr17_+_34808772 0.64 ENSMUST00000038244.15
G-protein signalling modulator 3 (AGS3-like, C. elegans)
chr7_-_30119227 0.63 ENSMUST00000208740.2
ENSMUST00000075062.5
hematopoietic cell signal transducer
chr19_+_4644365 0.63 ENSMUST00000113825.4
pyruvate carboxylase
chr7_-_19338349 0.63 ENSMUST00000086041.7
CLK4-associating serine/arginine rich protein
chr4_-_117744476 0.61 ENSMUST00000132073.2
ENSMUST00000150204.8
ENSMUST00000147845.2
ENSMUST00000036380.14
ENSMUST00000136596.2
ATPase, H+ transporting, lysosomal V0 subunit B
chr19_-_53020531 0.61 ENSMUST00000236008.2
ENSMUST00000237294.2
X-prolyl aminopeptidase (aminopeptidase P) 1, soluble
chr15_+_44320918 0.60 ENSMUST00000038336.12
ENSMUST00000166957.2
ENSMUST00000209244.2
polycystic kidney and hepatic disease 1-like 1
chr1_+_74414354 0.60 ENSMUST00000187516.7
ENSMUST00000027368.6
solute carrier family 11 (proton-coupled divalent metal ion transporters), member 1
chr6_+_92846338 0.60 ENSMUST00000113434.2
predicted gene 15737
chr14_+_65187485 0.59 ENSMUST00000043914.8
ENSMUST00000239450.2
integrator complex subunit 9
chr13_+_21364069 0.58 ENSMUST00000021761.13
tripartite motif-containing 27
chr8_+_55024446 0.58 ENSMUST00000239166.2
ENSMUST00000239106.2
ENSMUST00000239152.2
ankyrin repeat and SOCs box-containing 5
chr5_-_65248962 0.58 ENSMUST00000212080.2
transmembrane protein 156
chr10_+_33780993 0.58 ENSMUST00000169670.8
radial spoke head 4 homolog A (Chlamydomonas)
chr18_+_50112580 0.57 ENSMUST00000179937.2
tumor necrosis factor, alpha-induced protein 8
chr7_-_126651120 0.57 ENSMUST00000051122.7
zymogen granule protein 16
chr19_-_4171536 0.56 ENSMUST00000025767.14
aryl-hydrocarbon receptor-interacting protein
chr2_+_149672760 0.56 ENSMUST00000109934.2
ENSMUST00000140870.8
synapse differentiation inducing 1
chr9_+_106158549 0.55 ENSMUST00000191434.2
POC1 centriolar protein A
chr12_-_32258604 0.55 ENSMUST00000053215.14
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma
chr2_+_149672708 0.55 ENSMUST00000109935.8
synapse differentiation inducing 1
chr12_-_76842263 0.54 ENSMUST00000082431.6
glutathione peroxidase 2
chr19_+_47167259 0.54 ENSMUST00000111808.11
neuralized E3 ubiquitin protein ligase 1A
chr14_+_79753055 0.53 ENSMUST00000110835.3
ENSMUST00000227192.2
E74-like factor 1
chr12_-_32258331 0.52 ENSMUST00000220366.2
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma
chr18_-_64649620 0.51 ENSMUST00000025483.11
ENSMUST00000237400.2
asparaginyl-tRNA synthetase
chr19_+_45352173 0.51 ENSMUST00000223764.2
ENSMUST00000065601.13
ENSMUST00000224102.2
ENSMUST00000111936.4
beta-transducin repeat containing protein
chr5_+_43976218 0.50 ENSMUST00000101237.8
bone marrow stromal cell antigen 1
chr9_+_69360902 0.50 ENSMUST00000034756.15
ENSMUST00000123470.8
annexin A2
chr12_-_8589545 0.50 ENSMUST00000095863.10
ENSMUST00000165657.3
solute carrier family 7 (cationic amino acid transporter, y+ system), member 15
chr17_-_27842412 0.50 ENSMUST00000025050.13
nudix (nucleotide diphosphate linked moiety X)-type motif 3
chr2_-_113678945 0.49 ENSMUST00000110949.9
Rho GTPase activating protein 11A
chr2_+_130969200 0.48 ENSMUST00000099349.10
ENSMUST00000100763.9
heat shock protein 12B
chr2_+_118493713 0.48 ENSMUST00000099557.10
p21 (RAC1) activated kinase 6
chr12_-_76869282 0.48 ENSMUST00000021459.14
RAB15, member RAS oncogene family
chr1_+_75483721 0.48 ENSMUST00000037330.5
inhibin alpha
chrX_+_162922317 0.47 ENSMUST00000112271.10
angiotensin I converting enzyme (peptidyl-dipeptidase A) 2
chr12_-_32258469 0.47 ENSMUST00000085469.6
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma
chr16_+_36648728 0.47 ENSMUST00000114819.8
ENSMUST00000023535.4
IQ calmodulin-binding motif containing 1
chr5_-_114828967 0.47 ENSMUST00000112212.2
ENSMUST00000112214.8
glycolipid transfer protein
chr4_+_155887978 0.47 ENSMUST00000030942.13
ENSMUST00000185148.8
ENSMUST00000130188.2
mitochondrial ribosomal protein L20
chr3_-_106313406 0.47 ENSMUST00000029510.9
chitinase-like 6
chr14_+_54713703 0.47 ENSMUST00000164697.8
rad and gem related GTP binding protein 2
chr11_-_69786324 0.47 ENSMUST00000001631.7
ArfGAP with coiled-coil, ankyrin repeat and PH domains 1
chr2_+_149672814 0.46 ENSMUST00000137280.2
ENSMUST00000149705.2
synapse differentiation inducing 1
chr1_+_135656885 0.45 ENSMUST00000027677.8
cysteine and glycine-rich protein 1
chr13_+_120761861 0.45 ENSMUST00000225029.2
cDNA sequence BC147527
chr2_-_152185901 0.45 ENSMUST00000040312.7
tribbles pseudokinase 3
chr11_-_54853729 0.44 ENSMUST00000108885.8
ENSMUST00000102730.9
ENSMUST00000018482.13
ENSMUST00000108886.8
ENSMUST00000102731.8
TNFAIP3 interacting protein 1
chr7_-_119078472 0.44 ENSMUST00000209095.2
ENSMUST00000033263.6
ENSMUST00000207261.2
uromodulin
chr10_+_83558729 0.44 ENSMUST00000150459.3
RIKEN cDNA 1500009L16 gene
chr2_+_158344532 0.44 ENSMUST00000059889.4
adipogenin
chr9_+_56772301 0.44 ENSMUST00000035661.7
chondroitin sulfate proteoglycan 4
chr18_-_52662728 0.43 ENSMUST00000025409.9
lysyl oxidase
chr2_-_167852538 0.42 ENSMUST00000099073.3
RIPOR family member 3
chr19_-_4213284 0.41 ENSMUST00000118483.2
ENSMUST00000155303.3
ribosomal protein S6 kinase, polypeptide 2
chr5_+_20112500 0.41 ENSMUST00000101558.10
membrane associated guanylate kinase, WW and PDZ domain containing 2
chr7_+_120411588 0.41 ENSMUST00000208668.2
predicted gene 5737
chr3_+_99161070 0.40 ENSMUST00000029462.10
T-box 15
chr15_+_51740825 0.40 ENSMUST00000137116.3
ENSMUST00000161651.2
ENSMUST00000059599.10
UTP23 small subunit processome component
chr10_-_49659355 0.40 ENSMUST00000105484.10
ENSMUST00000218598.2
ENSMUST00000079751.9
ENSMUST00000218441.2
glutamate receptor, ionotropic, kainate 2 (beta 2)
chr4_-_41731142 0.40 ENSMUST00000171251.8
AT rich interactive domain 3C (BRIGHT-like)
chr1_-_130815144 0.40 ENSMUST00000121040.8
interleukin 24
chr19_-_47680528 0.39 ENSMUST00000026045.14
ENSMUST00000086923.6
collagen, type XVII, alpha 1
chr7_-_30262659 0.39 ENSMUST00000043898.8
presenilin enhancer gamma secretase subunit
chr15_-_101759212 0.39 ENSMUST00000023790.5
keratin 1
chr4_+_134042423 0.39 ENSMUST00000105875.8
ENSMUST00000030638.7
tripartite motif-containing 63
chr5_+_67125902 0.39 ENSMUST00000127184.8
LIM and calponin homology domains 1
chr5_-_121045568 0.38 ENSMUST00000080322.8
2'-5' oligoadenylate synthetase 1A
chr1_-_75168567 0.38 ENSMUST00000040689.15
ENSMUST00000189702.7
autophagy related 9A
chr7_-_30262337 0.38 ENSMUST00000207031.2
presenilin enhancer gamma secretase subunit
chr5_+_20112704 0.38 ENSMUST00000115267.7
membrane associated guanylate kinase, WW and PDZ domain containing 2
chr2_+_84966569 0.37 ENSMUST00000057019.9
apelin receptor
chr18_-_64649497 0.37 ENSMUST00000237351.2
ENSMUST00000236186.2
ENSMUST00000235325.2
asparaginyl-tRNA synthetase
chr3_-_141874955 0.37 ENSMUST00000098568.8
bone morphogenetic protein receptor, type 1B
chr6_-_68887922 0.36 ENSMUST00000103337.3
immunoglobulin kappa variable 4-86
chr6_-_128332789 0.36 ENSMUST00000001562.9
tubby-like protein 3

Network of associatons between targets according to the STRING database.

First level regulatory network of Hand1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.8 5.3 GO:0051714 regulation of cytolysis in other organism(GO:0051710) positive regulation of cytolysis in other organism(GO:0051714)
1.1 3.4 GO:2000295 regulation of hydrogen peroxide catabolic process(GO:2000295)
1.0 8.1 GO:1901748 peptide modification(GO:0031179) leukotriene D4 metabolic process(GO:1901748) leukotriene D4 biosynthetic process(GO:1901750)
0.8 4.6 GO:0002528 regulation of vascular permeability involved in acute inflammatory response(GO:0002528)
0.8 8.3 GO:0030886 negative regulation of myeloid dendritic cell activation(GO:0030886)
0.6 2.6 GO:0009298 GDP-mannose biosynthetic process(GO:0009298)
0.6 1.8 GO:0015825 L-serine transport(GO:0015825)
0.5 1.6 GO:0061193 taste bud development(GO:0061193)
0.5 1.6 GO:0006429 leucyl-tRNA aminoacylation(GO:0006429)
0.4 8.0 GO:0043249 erythrocyte maturation(GO:0043249)
0.4 1.9 GO:0035617 stress granule disassembly(GO:0035617)
0.3 3.9 GO:0006228 UTP biosynthetic process(GO:0006228)
0.3 0.8 GO:0002277 myeloid dendritic cell activation involved in immune response(GO:0002277) positive regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002582) positive regulation of antigen processing and presentation of peptide antigen via MHC class II(GO:0002588)
0.3 0.8 GO:0071874 cellular response to norepinephrine stimulus(GO:0071874)
0.2 1.0 GO:1902268 negative regulation of polyamine transmembrane transport(GO:1902268)
0.2 1.2 GO:0034224 cellular response to zinc ion starvation(GO:0034224)
0.2 2.2 GO:0045654 positive regulation of megakaryocyte differentiation(GO:0045654)
0.2 0.7 GO:1904879 positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1904879)
0.2 1.3 GO:1900041 negative regulation of interleukin-2 secretion(GO:1900041)
0.2 0.8 GO:0071544 diphosphoinositol polyphosphate catabolic process(GO:0071544)
0.2 1.4 GO:0051697 protein delipidation(GO:0051697)
0.2 1.6 GO:0097428 protein maturation by iron-sulfur cluster transfer(GO:0097428)
0.2 0.6 GO:0070839 divalent metal ion export(GO:0070839)
0.2 1.0 GO:1902167 positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:1902167)
0.2 1.2 GO:1901842 negative regulation of high voltage-gated calcium channel activity(GO:1901842)
0.2 1.5 GO:0010897 negative regulation of triglyceride catabolic process(GO:0010897)
0.2 0.9 GO:0070966 nuclear-transcribed mRNA catabolic process, no-go decay(GO:0070966)
0.2 0.9 GO:0050902 leukocyte adhesive activation(GO:0050902)
0.2 0.9 GO:0006421 asparaginyl-tRNA aminoacylation(GO:0006421)
0.2 0.9 GO:0038032 termination of G-protein coupled receptor signaling pathway(GO:0038032)
0.2 0.7 GO:0060434 bronchus morphogenesis(GO:0060434)
0.2 1.3 GO:0007253 cytoplasmic sequestering of NF-kappaB(GO:0007253)
0.2 2.6 GO:0050862 positive regulation of T cell receptor signaling pathway(GO:0050862)
0.2 2.3 GO:0072378 blood coagulation, fibrin clot formation(GO:0072378)
0.2 1.1 GO:0038165 oncostatin-M-mediated signaling pathway(GO:0038165)
0.2 0.5 GO:0071640 regulation of macrophage inflammatory protein 1 alpha production(GO:0071640)
0.1 1.8 GO:0071394 cellular response to testosterone stimulus(GO:0071394)
0.1 0.9 GO:0010890 positive regulation of sequestering of triglyceride(GO:0010890)
0.1 0.3 GO:0097021 lymphocyte migration into lymphoid organs(GO:0097021)
0.1 0.7 GO:0061622 glycolytic process through glucose-1-phosphate(GO:0061622)
0.1 0.6 GO:0051344 negative regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051344)
0.1 0.5 GO:0009608 response to symbiont(GO:0009608) response to symbiotic bacterium(GO:0009609)
0.1 0.7 GO:0001692 histamine metabolic process(GO:0001692) histidine catabolic process(GO:0006548)
0.1 0.6 GO:0019072 viral genome packaging(GO:0019072) viral RNA genome packaging(GO:0019074)
0.1 1.3 GO:0034723 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.1 0.5 GO:0015827 aromatic amino acid transport(GO:0015801) tryptophan transport(GO:0015827)
0.1 1.0 GO:0032532 regulation of microvillus length(GO:0032532)
0.1 0.7 GO:0032804 negative regulation of low-density lipoprotein particle receptor catabolic process(GO:0032804)
0.1 0.7 GO:0000160 phosphorelay signal transduction system(GO:0000160)
0.1 0.4 GO:0072218 ascending thin limb development(GO:0072021) thick ascending limb development(GO:0072023) metanephric ascending thin limb development(GO:0072218) metanephric thick ascending limb development(GO:0072233)
0.1 0.3 GO:0036090 cleavage furrow ingression(GO:0036090)
0.1 0.3 GO:0006500 N-terminal protein palmitoylation(GO:0006500)
0.1 0.5 GO:0021965 spinal cord ventral commissure morphogenesis(GO:0021965)
0.1 0.3 GO:0007208 phospholipase C-activating serotonin receptor signaling pathway(GO:0007208)
0.1 0.3 GO:1902277 negative regulation of pancreatic amylase secretion(GO:1902277)
0.1 0.5 GO:0046882 negative regulation of follicle-stimulating hormone secretion(GO:0046882)
0.1 0.4 GO:0002030 inhibitory G-protein coupled receptor phosphorylation(GO:0002030)
0.1 0.6 GO:0003431 growth plate cartilage chondrocyte development(GO:0003431)
0.1 1.1 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.1 0.3 GO:2001178 mediator complex assembly(GO:0036034) regulation of mediator complex assembly(GO:2001176) positive regulation of mediator complex assembly(GO:2001178)
0.1 0.4 GO:0060382 release from viral latency(GO:0019046) regulation of DNA strand elongation(GO:0060382)
0.1 2.3 GO:0097091 synaptic vesicle clustering(GO:0097091)
0.1 0.2 GO:0006435 threonyl-tRNA aminoacylation(GO:0006435)
0.1 0.2 GO:0031117 positive regulation of microtubule depolymerization(GO:0031117)
0.1 1.8 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.1 0.4 GO:0000480 endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000480)
0.1 0.2 GO:0071929 alpha-tubulin acetylation(GO:0071929)
0.1 0.4 GO:0046341 CDP-diacylglycerol metabolic process(GO:0046341)
0.1 0.2 GO:0042494 detection of bacterial lipoprotein(GO:0042494)
0.1 0.4 GO:0048165 ovarian cumulus expansion(GO:0001550) fused antrum stage(GO:0048165)
0.1 1.9 GO:0030213 hyaluronan biosynthetic process(GO:0030213)
0.1 0.4 GO:1990504 dense core granule exocytosis(GO:1990504)
0.1 1.8 GO:2000193 positive regulation of fatty acid transport(GO:2000193)
0.1 0.4 GO:0032747 positive regulation of interleukin-23 production(GO:0032747)
0.1 0.2 GO:0051385 response to mineralocorticoid(GO:0051385)
0.1 0.5 GO:0048496 maintenance of organ identity(GO:0048496)
0.1 1.2 GO:0036297 interstrand cross-link repair(GO:0036297)
0.1 1.4 GO:0007250 activation of NF-kappaB-inducing kinase activity(GO:0007250)
0.1 0.6 GO:0010815 bradykinin catabolic process(GO:0010815)
0.1 0.8 GO:1990035 calcium ion import across plasma membrane(GO:0098703) calcium ion import into cell(GO:1990035)
0.1 0.5 GO:0044805 late nucleophagy(GO:0044805)
0.1 0.2 GO:0035624 receptor transactivation(GO:0035624) epidermal growth factor-activated receptor transactivation by G-protein coupled receptor signaling pathway(GO:0035625)
0.1 0.2 GO:0014878 response to electrical stimulus involved in regulation of muscle adaptation(GO:0014878)
0.1 0.3 GO:2001023 regulation of response to drug(GO:2001023)
0.1 2.7 GO:0030225 macrophage differentiation(GO:0030225)
0.1 0.3 GO:0045590 negative regulation of regulatory T cell differentiation(GO:0045590)
0.1 1.9 GO:0090022 regulation of neutrophil chemotaxis(GO:0090022)
0.1 0.2 GO:0010925 regulation of inositol-polyphosphate 5-phosphatase activity(GO:0010924) positive regulation of inositol-polyphosphate 5-phosphatase activity(GO:0010925) phospholipase C-inhibiting G-protein coupled receptor signaling pathway(GO:0030845) regulation of cell diameter(GO:0060305)
0.1 0.1 GO:2000417 negative regulation of eosinophil migration(GO:2000417)
0.1 1.1 GO:0007220 Notch receptor processing(GO:0007220)
0.1 0.5 GO:0006030 chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032)
0.1 0.2 GO:0045896 regulation of transcription during mitosis(GO:0045896) positive regulation of transcription during mitosis(GO:0045897)
0.1 0.3 GO:0070543 response to linoleic acid(GO:0070543)
0.1 3.6 GO:0045604 regulation of epidermal cell differentiation(GO:0045604)
0.1 1.0 GO:0043312 neutrophil degranulation(GO:0043312)
0.0 0.9 GO:0045292 mRNA cis splicing, via spliceosome(GO:0045292)
0.0 1.6 GO:0044381 glucose import in response to insulin stimulus(GO:0044381)
0.0 1.0 GO:0031115 negative regulation of microtubule polymerization(GO:0031115)
0.0 0.4 GO:1903003 positive regulation of protein deubiquitination(GO:1903003)
0.0 0.2 GO:0002101 tRNA wobble cytosine modification(GO:0002101)
0.0 0.3 GO:0050915 sensory perception of sour taste(GO:0050915)
0.0 0.5 GO:0045741 positive regulation of epidermal growth factor-activated receptor activity(GO:0045741)
0.0 1.0 GO:0046185 aldehyde catabolic process(GO:0046185)
0.0 0.6 GO:0035092 sperm chromatin condensation(GO:0035092)
0.0 0.6 GO:1900017 positive regulation of cytokine production involved in inflammatory response(GO:1900017)
0.0 2.9 GO:0060325 face morphogenesis(GO:0060325)
0.0 0.7 GO:0002446 neutrophil mediated immunity(GO:0002446)
0.0 1.2 GO:0045948 positive regulation of translational initiation(GO:0045948)
0.0 0.2 GO:0015888 thiamine transport(GO:0015888)
0.0 0.3 GO:0060770 negative regulation of epithelial cell proliferation involved in prostate gland development(GO:0060770)
0.0 1.0 GO:0001833 inner cell mass cell proliferation(GO:0001833)
0.0 0.5 GO:0018298 protein-chromophore linkage(GO:0018298)
0.0 0.2 GO:0021633 optic nerve structural organization(GO:0021633)
0.0 0.1 GO:0010916 regulation of very-low-density lipoprotein particle clearance(GO:0010915) negative regulation of very-low-density lipoprotein particle clearance(GO:0010916)
0.0 0.6 GO:0016180 snRNA processing(GO:0016180)
0.0 0.6 GO:0035428 hexose transmembrane transport(GO:0035428)
0.0 0.7 GO:0000469 cleavage involved in rRNA processing(GO:0000469)
0.0 0.4 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.0 0.3 GO:0033085 negative regulation of T cell differentiation in thymus(GO:0033085)
0.0 0.3 GO:0000055 ribosomal large subunit export from nucleus(GO:0000055) ribosomal small subunit export from nucleus(GO:0000056)
0.0 0.4 GO:0007213 G-protein coupled acetylcholine receptor signaling pathway(GO:0007213)
0.0 0.1 GO:0032025 response to cobalt ion(GO:0032025) negative regulation of mitochondrial membrane permeability involved in apoptotic process(GO:1902109)
0.0 0.1 GO:0032918 polyamine acetylation(GO:0032917) spermidine acetylation(GO:0032918)
0.0 0.2 GO:0032489 regulation of Cdc42 protein signal transduction(GO:0032489)
0.0 0.3 GO:0045040 protein import into mitochondrial outer membrane(GO:0045040)
0.0 0.1 GO:0009223 pyrimidine nucleotide catabolic process(GO:0006244) pyrimidine deoxyribonucleotide catabolic process(GO:0009223)
0.0 2.9 GO:0006970 response to osmotic stress(GO:0006970)
0.0 0.3 GO:1900113 negative regulation of histone H3-K9 trimethylation(GO:1900113)
0.0 0.2 GO:0009240 isopentenyl diphosphate biosynthetic process(GO:0009240) isopentenyl diphosphate metabolic process(GO:0046490)
0.0 0.1 GO:0099628 receptor diffusion trapping(GO:0098953) postsynaptic neurotransmitter receptor diffusion trapping(GO:0098970) neurotransmitter receptor diffusion trapping(GO:0099628)
0.0 0.5 GO:0045717 negative regulation of fatty acid biosynthetic process(GO:0045717)
0.0 0.0 GO:0061743 motor learning(GO:0061743)
0.0 0.7 GO:0042789 mRNA transcription from RNA polymerase II promoter(GO:0042789)
0.0 0.3 GO:0051418 interphase microtubule nucleation by interphase microtubule organizing center(GO:0051415) microtubule nucleation by microtubule organizing center(GO:0051418)
0.0 0.7 GO:0050872 white fat cell differentiation(GO:0050872)
0.0 0.2 GO:0048549 positive regulation of pinocytosis(GO:0048549)
0.0 0.2 GO:0038031 non-canonical Wnt signaling pathway via JNK cascade(GO:0038031)
0.0 0.7 GO:0034508 centromere complex assembly(GO:0034508)
0.0 0.1 GO:0042138 meiotic DNA double-strand break formation(GO:0042138)
0.0 0.1 GO:2000143 negative regulation of DNA-templated transcription, initiation(GO:2000143)
0.0 1.1 GO:0048488 synaptic vesicle endocytosis(GO:0048488)
0.0 0.2 GO:0032482 Rab protein signal transduction(GO:0032482)
0.0 0.0 GO:0090362 positive regulation of platelet-derived growth factor production(GO:0090362)
0.0 0.2 GO:0031914 negative regulation of synaptic plasticity(GO:0031914)
0.0 0.2 GO:0046598 positive regulation of viral entry into host cell(GO:0046598)
0.0 0.2 GO:0046477 glycosylceramide catabolic process(GO:0046477)
0.0 0.5 GO:0035641 locomotory exploration behavior(GO:0035641)
0.0 0.3 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.0 0.8 GO:0006904 vesicle docking involved in exocytosis(GO:0006904)
0.0 0.3 GO:0021520 spinal cord motor neuron cell fate specification(GO:0021520)
0.0 0.3 GO:0035067 negative regulation of histone acetylation(GO:0035067)
0.0 0.4 GO:0071420 cellular response to histamine(GO:0071420)
0.0 0.4 GO:0045899 positive regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045899)
0.0 0.6 GO:0015988 energy coupled proton transmembrane transport, against electrochemical gradient(GO:0015988) ATP hydrolysis coupled proton transport(GO:0015991)
0.0 1.1 GO:0003341 cilium movement(GO:0003341)
0.0 1.0 GO:0007019 microtubule depolymerization(GO:0007019)
0.0 0.1 GO:0006116 NADH oxidation(GO:0006116)
0.0 0.0 GO:0032277 negative regulation of gonadotropin secretion(GO:0032277)
0.0 0.2 GO:1901249 regulation of lung goblet cell differentiation(GO:1901249) negative regulation of lung goblet cell differentiation(GO:1901250)
0.0 0.1 GO:0009313 oligosaccharide catabolic process(GO:0009313)
0.0 0.1 GO:0097309 cap1 mRNA methylation(GO:0097309)
0.0 0.2 GO:0030322 stabilization of membrane potential(GO:0030322)
0.0 0.5 GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
0.0 0.1 GO:0060467 negative regulation of fertilization(GO:0060467)
0.0 0.2 GO:0090043 regulation of tubulin deacetylation(GO:0090043)
0.0 0.5 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.0 0.3 GO:0055003 cardiac myofibril assembly(GO:0055003)
0.0 1.1 GO:2000649 regulation of sodium ion transmembrane transporter activity(GO:2000649)
0.0 0.1 GO:0070200 establishment of protein localization to telomere(GO:0070200)
0.0 0.2 GO:0061158 3'-UTR-mediated mRNA destabilization(GO:0061158)
0.0 0.1 GO:0051835 positive regulation of synapse structural plasticity(GO:0051835)
0.0 0.1 GO:0010796 regulation of multivesicular body size(GO:0010796)
0.0 0.2 GO:0006614 SRP-dependent cotranslational protein targeting to membrane(GO:0006614)
0.0 0.3 GO:0014883 transition between fast and slow fiber(GO:0014883)
0.0 0.3 GO:0022027 interkinetic nuclear migration(GO:0022027)
0.0 0.4 GO:0050860 negative regulation of T cell receptor signaling pathway(GO:0050860)
0.0 0.1 GO:0051204 protein insertion into mitochondrial membrane(GO:0051204)
0.0 0.2 GO:1902260 negative regulation of delayed rectifier potassium channel activity(GO:1902260)
0.0 0.5 GO:0007339 binding of sperm to zona pellucida(GO:0007339)
0.0 0.4 GO:0042501 serine phosphorylation of STAT protein(GO:0042501)
0.0 0.1 GO:0031666 positive regulation of lipopolysaccharide-mediated signaling pathway(GO:0031666)
0.0 0.8 GO:0015908 fatty acid transport(GO:0015908)
0.0 0.2 GO:0016322 neuron remodeling(GO:0016322)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.7 8.3 GO:0070442 integrin alphaIIb-beta3 complex(GO:0070442)
0.8 3.4 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.4 2.9 GO:0005833 hemoglobin complex(GO:0005833)
0.3 1.3 GO:0033186 CAF-1 complex(GO:0033186)
0.3 1.3 GO:0005594 collagen type IX trimer(GO:0005594)
0.3 1.5 GO:0005944 phosphatidylinositol 3-kinase complex, class IB(GO:0005944)
0.2 0.7 GO:1990667 PCSK9-AnxA2 complex(GO:1990667)
0.2 4.1 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.2 0.8 GO:0097169 AIM2 inflammasome complex(GO:0097169)
0.2 1.1 GO:0031314 extrinsic component of mitochondrial inner membrane(GO:0031314)
0.2 0.7 GO:0070722 Tle3-Aes complex(GO:0070722)
0.2 0.5 GO:0043512 inhibin-betaglycan-ActRII complex(GO:0034673) inhibin A complex(GO:0043512)
0.2 2.3 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.1 0.6 GO:0030312 external encapsulating structure(GO:0030312)
0.1 0.7 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.1 1.4 GO:0000235 astral microtubule(GO:0000235)
0.1 0.3 GO:0032783 ELL-EAF complex(GO:0032783)
0.1 0.6 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
0.1 1.6 GO:0042555 MCM complex(GO:0042555)
0.1 1.6 GO:0030061 mitochondrial crista(GO:0030061)
0.1 1.9 GO:0042589 zymogen granule membrane(GO:0042589)
0.1 1.1 GO:0070765 gamma-secretase complex(GO:0070765)
0.1 1.6 GO:0032593 insulin-responsive compartment(GO:0032593)
0.1 1.4 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.1 1.3 GO:0031254 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.1 0.6 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.1 0.3 GO:1902937 inward rectifier potassium channel complex(GO:1902937)
0.1 0.7 GO:0030991 intraciliary transport particle A(GO:0030991)
0.1 0.3 GO:0008275 gamma-tubulin small complex(GO:0008275)
0.1 0.7 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.1 0.7 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.0 0.4 GO:0032983 kainate selective glutamate receptor complex(GO:0032983)
0.0 0.1 GO:0099573 glutamatergic postsynaptic density(GO:0099573)
0.0 0.8 GO:0036056 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.0 0.6 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.0 1.3 GO:0030904 retromer complex(GO:0030904)
0.0 0.2 GO:0097447 dendritic tree(GO:0097447)
0.0 0.5 GO:0032584 growth cone membrane(GO:0032584)
0.0 3.2 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.0 0.9 GO:0032426 stereocilium tip(GO:0032426)
0.0 0.2 GO:0071203 WASH complex(GO:0071203)
0.0 2.0 GO:0031901 early endosome membrane(GO:0031901)
0.0 6.6 GO:0030863 cortical cytoskeleton(GO:0030863)
0.0 1.4 GO:0097440 apical dendrite(GO:0097440)
0.0 0.6 GO:0032039 integrator complex(GO:0032039)
0.0 0.3 GO:1990635 proximal dendrite(GO:1990635)
0.0 0.2 GO:0044305 calyx of Held(GO:0044305)
0.0 0.1 GO:0070876 SOSS complex(GO:0070876)
0.0 2.4 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 1.9 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0 0.2 GO:0097427 microtubule bundle(GO:0097427)
0.0 0.2 GO:0089701 U2AF(GO:0089701)
0.0 0.3 GO:0070938 contractile ring(GO:0070938)
0.0 1.0 GO:0005771 multivesicular body(GO:0005771)
0.0 1.9 GO:0099501 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.0 0.3 GO:0031232 extrinsic component of external side of plasma membrane(GO:0031232)
0.0 0.2 GO:0005786 signal recognition particle, endoplasmic reticulum targeting(GO:0005786)
0.0 0.5 GO:1902711 GABA-A receptor complex(GO:1902711)
0.0 0.4 GO:0042627 chylomicron(GO:0042627)
0.0 0.3 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.0 0.1 GO:1990130 Iml1 complex(GO:1990130)
0.0 0.1 GO:0048237 rough endoplasmic reticulum lumen(GO:0048237)
0.0 0.1 GO:0042585 germinal vesicle(GO:0042585)
0.0 0.2 GO:0043203 axon hillock(GO:0043203)
0.0 0.2 GO:0036156 inner dynein arm(GO:0036156)
0.0 0.5 GO:0000421 autophagosome membrane(GO:0000421)
0.0 0.3 GO:0005861 troponin complex(GO:0005861)
0.0 1.4 GO:0005811 lipid particle(GO:0005811)
0.0 0.1 GO:0005964 phosphorylase kinase complex(GO:0005964)
0.0 0.4 GO:0030056 hemidesmosome(GO:0030056)
0.0 0.7 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.0 0.4 GO:0001533 cornified envelope(GO:0001533)
0.0 0.6 GO:0032809 neuronal cell body membrane(GO:0032809)
0.0 1.4 GO:0030136 clathrin-coated vesicle(GO:0030136)
0.0 0.2 GO:0000124 SAGA complex(GO:0000124)
0.0 0.3 GO:0005865 striated muscle thin filament(GO:0005865)
0.0 0.3 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.0 0.4 GO:0032040 small-subunit processome(GO:0032040)
0.0 0.3 GO:0005838 proteasome regulatory particle(GO:0005838)
0.0 0.2 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.0 0.5 GO:0032391 photoreceptor connecting cilium(GO:0032391)
0.0 1.1 GO:0043198 dendritic shaft(GO:0043198)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 5.3 GO:0016019 N-acetylmuramoyl-L-alanine amidase activity(GO:0008745) peptidoglycan receptor activity(GO:0016019)
0.9 2.6 GO:0004615 phosphomannomutase activity(GO:0004615)
0.7 7.3 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.6 7.8 GO:0036374 glutathione hydrolase activity(GO:0036374)
0.5 1.6 GO:0005169 neurotrophin TRKB receptor binding(GO:0005169)
0.5 4.7 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.5 1.6 GO:0004823 leucine-tRNA ligase activity(GO:0004823)
0.4 3.9 GO:1901612 cardiolipin binding(GO:1901612)
0.3 1.0 GO:0052658 inositol-1,4,5-trisphosphate 5-phosphatase activity(GO:0052658)
0.3 2.9 GO:0005344 oxygen transporter activity(GO:0005344)
0.3 1.6 GO:0055056 D-glucose transmembrane transporter activity(GO:0055056)
0.3 3.4 GO:1903136 cuprous ion binding(GO:1903136)
0.3 1.2 GO:0004711 ribosomal protein S6 kinase activity(GO:0004711)
0.3 2.6 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.3 0.9 GO:0004461 lactose synthase activity(GO:0004461)
0.2 1.0 GO:0008073 ornithine decarboxylase inhibitor activity(GO:0008073)
0.2 0.9 GO:0004816 asparagine-tRNA ligase activity(GO:0004816)
0.2 2.0 GO:0050786 RAGE receptor binding(GO:0050786)
0.2 0.8 GO:0031694 alpha-2A adrenergic receptor binding(GO:0031694)
0.2 0.6 GO:0036004 GAF domain binding(GO:0036004)
0.2 0.6 GO:0004736 pyruvate carboxylase activity(GO:0004736)
0.2 1.9 GO:0008061 chitin binding(GO:0008061)
0.1 0.7 GO:0003872 6-phosphofructokinase activity(GO:0003872)
0.1 1.8 GO:0022889 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.1 4.1 GO:0016676 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.1 0.5 GO:0045183 translation factor activity, non-nucleic acid binding(GO:0045183)
0.1 0.4 GO:0003881 CDP-diacylglycerol-inositol 3-phosphatidyltransferase activity(GO:0003881)
0.1 0.8 GO:0030250 cyclase activator activity(GO:0010853) guanylate cyclase activator activity(GO:0030250)
0.1 0.5 GO:0003953 NAD+ nucleosidase activity(GO:0003953)
0.1 1.0 GO:0008823 ferric-chelate reductase activity(GO:0000293) cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
0.1 1.3 GO:0070087 chromo shadow domain binding(GO:0070087)
0.1 0.8 GO:0008486 endopolyphosphatase activity(GO:0000298) diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) bis(5'-adenosyl)-hexaphosphatase activity(GO:0034431) bis(5'-adenosyl)-pentaphosphatase activity(GO:0034432)
0.1 1.5 GO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol bisphosphate kinase activity(GO:0052813)
0.1 3.0 GO:0004707 MAP kinase activity(GO:0004707)
0.1 0.7 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.1 0.8 GO:0070699 type II activin receptor binding(GO:0070699)
0.1 0.7 GO:0000155 phosphorelay sensor kinase activity(GO:0000155)
0.1 0.8 GO:0005087 Ran guanyl-nucleotide exchange factor activity(GO:0005087)
0.1 1.0 GO:0004030 aldehyde dehydrogenase [NAD(P)+] activity(GO:0004030)
0.1 0.3 GO:0030116 glial cell-derived neurotrophic factor receptor binding(GO:0030116)
0.1 0.7 GO:0086056 voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056)
0.1 3.0 GO:0070182 DNA polymerase binding(GO:0070182)
0.1 0.8 GO:0004321 fatty-acyl-CoA synthase activity(GO:0004321)
0.1 0.2 GO:0004829 threonine-tRNA ligase activity(GO:0004829)
0.1 0.8 GO:0005138 interleukin-6 receptor binding(GO:0005138)
0.1 0.2 GO:0004938 alpha2-adrenergic receptor activity(GO:0004938)
0.1 0.5 GO:0008241 peptidyl-dipeptidase activity(GO:0008241)
0.1 0.4 GO:0030280 structural constituent of epidermis(GO:0030280)
0.1 0.7 GO:0019834 phospholipase A2 inhibitor activity(GO:0019834)
0.1 0.7 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.1 0.2 GO:0052692 raffinose alpha-galactosidase activity(GO:0052692)
0.1 0.3 GO:0070052 collagen V binding(GO:0070052)
0.1 0.5 GO:0034711 inhibin binding(GO:0034711)
0.1 0.4 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.1 0.5 GO:0005042 netrin receptor activity(GO:0005042)
0.1 0.2 GO:0001565 phorbol ester receptor activity(GO:0001565) non-kinase phorbol ester receptor activity(GO:0001566)
0.1 0.2 GO:0034739 histone deacetylase activity (H4-K16 specific)(GO:0034739)
0.1 0.3 GO:0070892 lipoteichoic acid receptor activity(GO:0070892)
0.1 0.5 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.0 1.2 GO:0051861 glycolipid binding(GO:0051861)
0.0 0.4 GO:0030229 very-low-density lipoprotein particle receptor activity(GO:0030229)
0.0 0.6 GO:0051378 serotonin binding(GO:0051378)
0.0 1.6 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.0 0.2 GO:0004999 vasoactive intestinal polypeptide receptor activity(GO:0004999)
0.0 0.2 GO:0004452 isopentenyl-diphosphate delta-isomerase activity(GO:0004452)
0.0 0.7 GO:0008379 thioredoxin peroxidase activity(GO:0008379)
0.0 0.3 GO:0004065 arylsulfatase activity(GO:0004065)
0.0 0.4 GO:0019864 IgG binding(GO:0019864)
0.0 0.4 GO:0022851 GABA-gated chloride ion channel activity(GO:0022851)
0.0 1.6 GO:0004003 ATP-dependent DNA helicase activity(GO:0004003)
0.0 0.6 GO:0015299 solute:proton antiporter activity(GO:0015299)
0.0 0.2 GO:0016499 orexin receptor activity(GO:0016499)
0.0 0.1 GO:0019809 spermidine binding(GO:0019809)
0.0 0.2 GO:0030942 endoplasmic reticulum signal peptide binding(GO:0030942)
0.0 0.4 GO:0070181 small ribosomal subunit rRNA binding(GO:0070181)
0.0 1.9 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
0.0 0.4 GO:0001730 2'-5'-oligoadenylate synthetase activity(GO:0001730)
0.0 0.2 GO:0032027 myosin light chain binding(GO:0032027)
0.0 1.9 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.0 0.4 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.0 0.2 GO:0043533 inositol 1,3,4,5 tetrakisphosphate binding(GO:0043533)
0.0 0.6 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0 1.2 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 3.9 GO:0005179 hormone activity(GO:0005179)
0.0 0.2 GO:0015018 galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018)
0.0 0.3 GO:0005412 glucose:sodium symporter activity(GO:0005412)
0.0 0.3 GO:0015266 protein channel activity(GO:0015266)
0.0 0.2 GO:0031628 opioid receptor binding(GO:0031628)
0.0 0.4 GO:0031432 titin binding(GO:0031432)
0.0 1.3 GO:0005044 scavenger receptor activity(GO:0005044)
0.0 0.2 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.0 0.5 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.0 0.6 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.0 0.2 GO:0052798 beta-galactoside alpha-2,3-sialyltransferase activity(GO:0052798)
0.0 0.3 GO:0015280 ligand-gated sodium channel activity(GO:0015280)
0.0 0.9 GO:0070064 proline-rich region binding(GO:0070064)
0.0 0.5 GO:0055106 ligase regulator activity(GO:0055103) ubiquitin-protein transferase regulator activity(GO:0055106)
0.0 0.2 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.0 0.4 GO:0015271 outward rectifier potassium channel activity(GO:0015271)
0.0 0.1 GO:0016997 exo-alpha-sialidase activity(GO:0004308) alpha-sialidase activity(GO:0016997) exo-alpha-(2->3)-sialidase activity(GO:0052794) exo-alpha-(2->6)-sialidase activity(GO:0052795) exo-alpha-(2->8)-sialidase activity(GO:0052796)
0.0 1.2 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.0 0.2 GO:1990829 C-rich single-stranded DNA binding(GO:1990829)
0.0 0.3 GO:0031386 protein tag(GO:0031386)
0.0 0.1 GO:0070326 very-low-density lipoprotein particle receptor binding(GO:0070326)
0.0 0.9 GO:0003785 actin monomer binding(GO:0003785)
0.0 0.6 GO:0045503 dynein light chain binding(GO:0045503)
0.0 1.9 GO:0035254 glutamate receptor binding(GO:0035254)
0.0 0.5 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.0 0.7 GO:0051059 NF-kappaB binding(GO:0051059)
0.0 0.6 GO:0017091 AU-rich element binding(GO:0017091)
0.0 0.7 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.0 0.1 GO:0003918 DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505)
0.0 0.9 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.0 2.4 GO:0004519 endonuclease activity(GO:0004519)
0.0 0.4 GO:0042923 neuropeptide binding(GO:0042923)
0.0 0.3 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.0 0.1 GO:0008889 glycerophosphodiester phosphodiesterase activity(GO:0008889)
0.0 0.3 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.0 0.1 GO:0008294 calcium- and calmodulin-responsive adenylate cyclase activity(GO:0008294)
0.0 0.2 GO:0030628 pre-mRNA 3'-splice site binding(GO:0030628)
0.0 0.3 GO:0005355 glucose transmembrane transporter activity(GO:0005355)
0.0 0.1 GO:0004689 phosphorylase kinase activity(GO:0004689)
0.0 1.0 GO:0017080 sodium channel regulator activity(GO:0017080)
0.0 0.3 GO:0051011 microtubule minus-end binding(GO:0051011)
0.0 0.6 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0 0.1 GO:0004483 mRNA (nucleoside-2'-O-)-methyltransferase activity(GO:0004483)
0.0 0.2 GO:0015926 glucosidase activity(GO:0015926)
0.0 0.1 GO:0015166 polyol transmembrane transporter activity(GO:0015166)
0.0 0.0 GO:0004995 tachykinin receptor activity(GO:0004995)
0.0 0.1 GO:0001055 RNA polymerase II activity(GO:0001055)
0.0 0.2 GO:0016805 dipeptidase activity(GO:0016805)
0.0 0.2 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.0 1.6 GO:0003774 motor activity(GO:0003774)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 3.0 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.1 2.5 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.1 3.4 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.1 1.1 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.0 0.8 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 1.6 PID EPHA FWDPATHWAY EPHA forward signaling
0.0 1.6 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.0 1.1 PID IL3 PATHWAY IL3-mediated signaling events
0.0 2.4 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.0 1.6 PID ATR PATHWAY ATR signaling pathway
0.0 1.8 NABA COLLAGENS Genes encoding collagen proteins
0.0 1.6 PID P75 NTR PATHWAY p75(NTR)-mediated signaling
0.0 1.0 PID AURORA A PATHWAY Aurora A signaling
0.0 2.4 ST FAS SIGNALING PATHWAY Fas Signaling Pathway
0.0 0.9 PID AMB2 NEUTROPHILS PATHWAY amb2 Integrin signaling
0.0 0.1 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0 0.8 PID PTP1B PATHWAY Signaling events mediated by PTP1B
0.0 0.8 ST T CELL SIGNAL TRANSDUCTION T Cell Signal Transduction
0.0 0.7 PID NETRIN PATHWAY Netrin-mediated signaling events
0.0 0.8 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 0.4 PID RHODOPSIN PATHWAY Visual signal transduction: Rods

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 3.5 REACTOME DSCAM INTERACTIONS Genes involved in DSCAM interactions
0.2 8.1 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.2 2.0 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.1 2.3 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.1 2.6 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.1 1.9 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.1 3.6 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.1 1.6 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.1 1.2 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.1 2.4 REACTOME AMYLOIDS Genes involved in Amyloids
0.1 1.8 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.1 1.1 REACTOME REGULATED PROTEOLYSIS OF P75NTR Genes involved in Regulated proteolysis of p75NTR
0.1 0.6 REACTOME SEROTONIN RECEPTORS Genes involved in Serotonin receptors
0.1 0.5 REACTOME OPSINS Genes involved in Opsins
0.0 2.6 REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.0 1.2 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.0 1.6 REACTOME TRANSFERRIN ENDOCYTOSIS AND RECYCLING Genes involved in Transferrin endocytosis and recycling
0.0 0.4 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.0 1.4 REACTOME KERATAN SULFATE BIOSYNTHESIS Genes involved in Keratan sulfate biosynthesis
0.0 0.5 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.0 0.3 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.0 0.5 REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.0 0.5 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.0 0.7 REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.0 0.7 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0 0.8 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.0 1.8 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.0 0.3 REACTOME CTLA4 INHIBITORY SIGNALING Genes involved in CTLA4 inhibitory signaling
0.0 1.8 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 4.0 REACTOME POTASSIUM CHANNELS Genes involved in Potassium Channels
0.0 0.8 REACTOME PIP3 ACTIVATES AKT SIGNALING Genes involved in PIP3 activates AKT signaling
0.0 0.5 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.0 1.4 REACTOME G1 PHASE Genes involved in G1 Phase
0.0 1.3 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0 2.3 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.0 0.5 REACTOME PROLACTIN RECEPTOR SIGNALING Genes involved in Prolactin receptor signaling
0.0 0.2 REACTOME REGULATION OF KIT SIGNALING Genes involved in Regulation of KIT signaling
0.0 1.2 REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC Genes involved in Regulation of ornithine decarboxylase (ODC)
0.0 2.8 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.0 0.2 REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING Genes involved in Role of second messengers in netrin-1 signaling
0.0 0.7 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.0 0.3 REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES Genes involved in Recruitment of NuMA to mitotic centrosomes
0.0 0.2 REACTOME N GLYCAN TRIMMING IN THE ER AND CALNEXIN CALRETICULIN CYCLE Genes involved in N-glycan trimming in the ER and Calnexin/Calreticulin cycle
0.0 2.1 REACTOME G ALPHA I SIGNALLING EVENTS Genes involved in G alpha (i) signalling events
0.0 0.4 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.0 0.3 REACTOME ANTIGEN PROCESSING CROSS PRESENTATION Genes involved in Antigen processing-Cross presentation