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GSE58827: Dynamics of the Mouse Liver

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Results for Hlf

Z-value: 1.11

Motif logo

Transcription factors associated with Hlf

Gene Symbol Gene ID Gene Info
ENSMUSG00000003949.17 hepatic leukemia factor

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Hlfmm39_v1_chr11_-_90281721_902817530.455.5e-03Click!

Activity profile of Hlf motif

Sorted Z-values of Hlf motif

Promoter Log-likelihood Transcript Gene Gene Info
chr16_+_22738987 14.38 ENSMUST00000023587.12
fetuin beta
chr16_+_22769822 11.41 ENSMUST00000023590.9
histidine-rich glycoprotein
chr6_+_121815473 11.03 ENSMUST00000032228.9
murinoglobulin 1
chr10_+_23727325 9.63 ENSMUST00000020190.8
vanin 3
chr16_+_22769844 9.58 ENSMUST00000232422.2
histidine-rich glycoprotein
chr7_+_26534730 9.13 ENSMUST00000005685.15
cytochrome P450, family 2, subfamily a, polypeptide 5
chr14_+_66208498 8.92 ENSMUST00000128539.8
clusterin
chr7_+_25872836 8.87 ENSMUST00000082214.5
cytochrome P450, family 2, subfamily b, polypeptide 9
chr12_-_81014755 8.55 ENSMUST00000218342.2
solute carrier family 10 (sodium/bile acid cotransporter family), member 1
chr16_+_22739191 8.50 ENSMUST00000116625.10
fetuin beta
chr16_+_22739028 7.88 ENSMUST00000232097.2
fetuin beta
chr14_+_66208613 7.85 ENSMUST00000144619.2
clusterin
chr11_+_115353290 7.33 ENSMUST00000106532.4
ENSMUST00000092445.12
ENSMUST00000153466.2
solute carrier family 16 (monocarboxylic acid transporters), member 5
chr7_-_46392403 7.23 ENSMUST00000128088.4
serum amyloid A 1
chr5_-_87074380 6.18 ENSMUST00000031183.3
UDP glucuronosyltransferase 2 family, polypeptide B1
chr7_+_26006594 6.14 ENSMUST00000098657.5
cytochrome P450, family 2, subfamily a, polypeptide 4
chr7_-_26638802 5.90 ENSMUST00000170227.3
cytochrome P450, family 2, subfamily a, polypeptide 22
chr9_-_71070506 5.50 ENSMUST00000074465.9
aquaporin 9
chr12_-_81014849 5.47 ENSMUST00000095572.5
solute carrier family 10 (sodium/bile acid cotransporter family), member 1
chr14_+_40827317 5.46 ENSMUST00000047286.7
methionine adenosyltransferase I, alpha
chr7_+_25760922 5.44 ENSMUST00000005669.9
cytochrome P450, family 2, subfamily b, polypeptide 13
chr9_-_78254422 5.40 ENSMUST00000034902.12
glutathione S-transferase, alpha 2 (Yc2)
chr1_-_140111138 4.89 ENSMUST00000111976.9
ENSMUST00000066859.13
complement component factor h
chr1_-_140111018 4.75 ENSMUST00000192880.6
ENSMUST00000111977.8
complement component factor h
chr15_-_3612078 4.73 ENSMUST00000161770.2
growth hormone receptor
chr12_-_104831266 4.70 ENSMUST00000109937.9
calmin
chr8_-_118398264 4.69 ENSMUST00000037955.14
short chain dehydrogenase/reductase family 42E, member 1
chr4_-_49408040 4.65 ENSMUST00000081541.9
acyl-coenzyme A amino acid N-acyltransferase 2
chr15_-_76191301 4.63 ENSMUST00000171340.9
ENSMUST00000023222.13
ENSMUST00000164189.2
5-oxoprolinase (ATP-hydrolysing)
chr7_+_46401214 4.34 ENSMUST00000210769.2
ENSMUST00000210272.2
ENSMUST00000075982.4
serum amyloid A 2
chr12_-_104831335 4.13 ENSMUST00000109936.3
calmin
chr3_-_113368407 4.09 ENSMUST00000106540.8
amylase 1, salivary
chr9_-_78254443 4.07 ENSMUST00000129247.2
glutathione S-transferase, alpha 2 (Yc2)
chr10_-_95678748 4.07 ENSMUST00000210336.2
predicted gene, 33543
chr7_-_30643444 4.05 ENSMUST00000062620.9
hepcidin antimicrobial peptide
chr13_+_25127127 3.69 ENSMUST00000021773.13
glycosylphosphatidylinositol specific phospholipase D1
chr10_-_125225298 3.65 ENSMUST00000210780.2
solute carrier family 16 (monocarboxylic acid transporters), member 7
chr5_-_87240405 3.40 ENSMUST00000132667.2
ENSMUST00000145617.8
ENSMUST00000094649.11
UDP glucuronosyltransferase 2 family, polypeptide B36
chr16_+_37400590 3.38 ENSMUST00000159787.8
homogentisate 1, 2-dioxygenase
chr16_+_37400500 3.35 ENSMUST00000160847.2
homogentisate 1, 2-dioxygenase
chr10_-_95678786 3.27 ENSMUST00000211096.2
predicted gene, 33543
chr5_-_92475927 3.24 ENSMUST00000113093.5
chemokine (C-X-C motif) ligand 9
chr15_+_99291491 3.14 ENSMUST00000159531.3
transmembrane BAX inhibitor motif containing 6
chr15_+_99291455 3.11 ENSMUST00000162624.8
transmembrane BAX inhibitor motif containing 6
chr19_+_58717319 3.01 ENSMUST00000048644.6
ENSMUST00000236445.2
pancreatic lipase related protein 1
chr19_+_38995463 2.99 ENSMUST00000025966.5
cytochrome P450, family 2, subfamily c, polypeptide 55
chr8_-_93956143 2.92 ENSMUST00000176282.2
ENSMUST00000034173.14
carboxylesterase 1E
chr19_-_7779943 2.87 ENSMUST00000120522.8
solute carrier family 22 (organic cation transporter), member 26
chr14_+_70815250 2.82 ENSMUST00000228554.2
nudix (nucleoside diphosphate linked moiety X)-type motif 18
chr9_-_107546195 2.81 ENSMUST00000192990.6
solute carrier family 38, member 3
chr10_-_78300802 2.74 ENSMUST00000041616.15
pyridoxal (pyridoxine, vitamin B6) kinase
chr5_+_135038267 2.72 ENSMUST00000201890.2
ENSMUST00000154469.8
abhydrolase domain containing 11
chr8_+_86219191 2.72 ENSMUST00000034136.12
glutamic pyruvate transaminase (alanine aminotransferase) 2
chr2_+_155118217 2.71 ENSMUST00000029128.4
microtubule-associated protein 1 light chain 3 alpha
chr8_+_46924074 2.70 ENSMUST00000034046.13
ENSMUST00000211644.2
acyl-CoA synthetase long-chain family member 1
chr9_-_107546166 2.68 ENSMUST00000177567.8
solute carrier family 38, member 3
chr17_+_79922329 2.64 ENSMUST00000040368.3
regulator of microtubule dynamics 2
chr16_-_22847808 2.58 ENSMUST00000115349.9
kininogen 2
chr6_+_113460258 2.55 ENSMUST00000032422.6
cysteine-rich with EGF-like domains 1
chr16_-_22847760 2.53 ENSMUST00000039338.13
kininogen 2
chr9_+_107957621 2.52 ENSMUST00000035211.14
macrophage stimulating 1 (hepatocyte growth factor-like)
chr16_-_22847829 2.47 ENSMUST00000100046.9
kininogen 2
chr9_+_107957640 2.46 ENSMUST00000162886.2
macrophage stimulating 1 (hepatocyte growth factor-like)
chr19_-_7780025 2.46 ENSMUST00000065634.8
solute carrier family 22 (organic cation transporter), member 26
chr5_-_5564730 2.45 ENSMUST00000115445.8
ENSMUST00000179804.8
ENSMUST00000125110.2
ENSMUST00000115446.8
claudin 12
chr5_+_135038006 2.42 ENSMUST00000111216.8
ENSMUST00000046999.12
abhydrolase domain containing 11
chr18_-_35631914 2.37 ENSMUST00000236007.2
ENSMUST00000237896.2
ENSMUST00000235778.2
ENSMUST00000235524.2
ENSMUST00000235691.2
ENSMUST00000235619.2
ENSMUST00000025215.10
endoplasmic reticulum chaperone SIL1 homolog (S. cerevisiae)
chr4_+_47208004 2.36 ENSMUST00000082303.13
ENSMUST00000102917.11
collagen, type XV, alpha 1
chr14_+_79086492 2.29 ENSMUST00000040990.7
von Willebrand factor A domain containing 8
chr16_-_38253507 2.27 ENSMUST00000002926.8
phospholipase A1 member A
chr5_-_5564873 2.27 ENSMUST00000060947.14
claudin 12
chr7_+_67297152 2.22 ENSMUST00000032774.16
ENSMUST00000107471.8
tetratricopeptide repeat domain 23
chr10_-_31321793 2.17 ENSMUST00000213639.2
ENSMUST00000215515.2
ENSMUST00000214644.2
ENSMUST00000213528.2
tumor protein D52-like 1
chr10_+_21253190 2.16 ENSMUST00000042699.14
aldehyde dehydrogenase 8 family, member A1
chr12_+_37291632 2.12 ENSMUST00000049874.14
alkylglycerol monooxygenase
chr16_+_3702604 2.11 ENSMUST00000115860.8
N(alpha)-acetyltransferase 60, NatF catalytic subunit
chr7_-_126873219 2.09 ENSMUST00000082428.6
selenophosphate synthetase 2
chr1_-_71692320 2.08 ENSMUST00000186940.7
ENSMUST00000188894.7
ENSMUST00000188674.7
ENSMUST00000189821.7
ENSMUST00000187938.7
ENSMUST00000190780.7
ENSMUST00000186736.2
ENSMUST00000055226.13
ENSMUST00000186129.7
fibronectin 1
chr2_+_118692435 2.07 ENSMUST00000028807.6
isovaleryl coenzyme A dehydrogenase
chr16_+_3702523 2.06 ENSMUST00000176625.8
ENSMUST00000186375.8
N(alpha)-acetyltransferase 60, NatF catalytic subunit
chr1_-_171173198 2.05 ENSMUST00000111295.8
ENSMUST00000148339.2
ENSMUST00000111289.8
nitrilase 1
chr12_+_37291728 2.00 ENSMUST00000160768.8
alkylglycerol monooxygenase
chr14_-_59835285 1.99 ENSMUST00000022555.11
ENSMUST00000225839.2
ENSMUST00000056997.15
ENSMUST00000171683.3
ENSMUST00000167100.9
cytidine and dCMP deaminase domain containing 1
chr10_+_78410180 1.98 ENSMUST00000218061.2
ENSMUST00000218787.2
ENSMUST00000105384.5
ENSMUST00000218875.2
ilvB (bacterial acetolactate synthase)-like
chr15_-_58953838 1.95 ENSMUST00000080371.8
MTSS I-BAR domain containing 1
chr1_-_171173168 1.94 ENSMUST00000156856.8
ENSMUST00000111296.8
nitrilase 1
chr16_-_87229485 1.90 ENSMUST00000039449.9
listerin E3 ubiquitin protein ligase 1
chr16_-_22848153 1.90 ENSMUST00000232459.2
kininogen 2
chr16_+_3702493 1.89 ENSMUST00000176233.2
predicted gene 20695
chr3_+_59939175 1.86 ENSMUST00000029325.5
arylacetamide deacetylase
chr5_-_147831610 1.82 ENSMUST00000118527.8
ENSMUST00000031655.4
ENSMUST00000138244.2
solute carrier family 46, member 3
chr6_-_115569504 1.81 ENSMUST00000112957.2
makorin, ring finger protein 2, opposite strand
chr10_-_115197775 1.80 ENSMUST00000217848.2
transmembrane protein 19
chr9_+_78197205 1.79 ENSMUST00000119823.8
ENSMUST00000121273.2
glutathione S-transferase alpha 5
chr3_-_129126362 1.77 ENSMUST00000029658.14
glutamyl aminopeptidase
chr11_-_69576363 1.72 ENSMUST00000018896.14
tumor necrosis factor (ligand) superfamily, member 13
chr16_-_4608084 1.71 ENSMUST00000118703.8
cell death inducing Trp53 target 1
chr19_+_34268053 1.69 ENSMUST00000025691.13
Fas (TNF receptor superfamily member 6)
chr5_-_31265562 1.66 ENSMUST00000201396.2
ENSMUST00000202740.4
solute carrier family 30 (zinc transporter), member 3
chrX_+_93278203 1.62 ENSMUST00000153900.8
kelch-like 15
chr16_-_4607751 1.62 ENSMUST00000117713.8
cell death inducing Trp53 target 1
chr13_+_114954741 1.59 ENSMUST00000166104.9
ENSMUST00000166176.9
ENSMUST00000184335.8
ENSMUST00000184245.8
ENSMUST00000015680.11
ENSMUST00000184214.8
ENSMUST00000165022.9
ENSMUST00000164737.8
ENSMUST00000184781.8
ENSMUST00000183407.2
ENSMUST00000184672.8
molybdenum cofactor synthesis 2
chr16_+_19916292 1.57 ENSMUST00000023509.5
ENSMUST00000232088.2
ENSMUST00000231842.2
kelch-like 24
chr16_-_93726399 1.53 ENSMUST00000177648.8
ENSMUST00000142083.2
claudin 14
chr11_+_118913788 1.51 ENSMUST00000026662.8
chromobox 2
chr12_+_110245662 1.49 ENSMUST00000097228.5
deiodinase, iodothyronine type III
chr11_-_77784922 1.49 ENSMUST00000017597.5
pipecolic acid oxidase
chr13_+_51254852 1.48 ENSMUST00000095797.6
spindlin 1
chr9_+_78137927 1.48 ENSMUST00000098537.4
glutathione S-transferase, alpha 1 (Ya)
chr12_+_73333553 1.48 ENSMUST00000140523.8
ENSMUST00000126488.8
solute carrier family 38, member 6
chr1_-_36748985 1.48 ENSMUST00000043951.10
ARP1 actin-related protein 1B, centractin beta
chr19_+_34268071 1.46 ENSMUST00000112472.4
ENSMUST00000235232.2
Fas (TNF receptor superfamily member 6)
chr16_-_4607848 1.43 ENSMUST00000004173.12
cell death inducing Trp53 target 1
chr3_+_138148846 1.43 ENSMUST00000005964.7
alcohol dehydrogenase 5 (class III), chi polypeptide
chr6_+_124785621 1.38 ENSMUST00000047760.10
splA/ryanodine receptor domain and SOCS box containing 2
chr7_-_45264908 1.38 ENSMUST00000033099.6
fibroblast growth factor 21
chr10_-_31321938 1.37 ENSMUST00000000305.7
tumor protein D52-like 1
chr16_-_87229367 1.35 ENSMUST00000232095.2
listerin E3 ubiquitin protein ligase 1
chr6_+_124785834 1.30 ENSMUST00000143040.8
ENSMUST00000052727.5
ENSMUST00000130160.2
splA/ryanodine receptor domain and SOCS box containing 2
chr6_+_90442269 1.30 ENSMUST00000113530.4
Kruppel-like factor 15
chr7_-_130924021 1.25 ENSMUST00000046611.9
CUB and zona pellucida-like domains 1
chr7_+_101859542 1.21 ENSMUST00000140631.2
ENSMUST00000120879.8
ENSMUST00000146996.8
post-GPI attachment to proteins 2
chr18_-_80194682 1.18 ENSMUST00000066743.11
ADNP homeobox 2
chr2_-_90735171 1.18 ENSMUST00000005647.4
NADH:ubiquinone oxidoreductase core subunit S3
chr11_-_6394385 1.13 ENSMUST00000109737.9
H2A.Z histone variant 2
chr7_+_44145987 1.09 ENSMUST00000107927.5
family with sequence similarity 71, member E1
chr7_+_44146012 1.08 ENSMUST00000205422.2
family with sequence similarity 71, member E1
chr7_-_7301760 1.05 ENSMUST00000210061.2
chloride channel, voltage-sensitive 4
chr19_+_31846154 1.05 ENSMUST00000224564.2
ENSMUST00000224304.2
ENSMUST00000075838.8
ENSMUST00000224400.2
APOBEC1 complementation factor
chr19_-_7183596 1.05 ENSMUST00000123594.8
OTU domain, ubiquitin aldehyde binding 1
chr6_+_90443293 1.05 ENSMUST00000203607.2
Kruppel-like factor 15
chr9_+_78164402 1.03 ENSMUST00000217203.2
predicted gene 3776
chr6_+_17463748 0.99 ENSMUST00000115443.8
met proto-oncogene
chr5_-_124170305 0.98 ENSMUST00000040967.9
vacuolar protein sorting 37B
chr4_-_41774097 0.98 ENSMUST00000108036.8
ENSMUST00000108037.9
ENSMUST00000108032.3
ENSMUST00000173865.9
ENSMUST00000155240.2
chemokine (C-C motif) ligand 27A
chr10_+_121575819 0.97 ENSMUST00000065600.8
ENSMUST00000136432.2
cDNA sequence BC048403
chr11_-_6394352 0.96 ENSMUST00000093346.6
H2A.Z histone variant 2
chr19_-_7183626 0.96 ENSMUST00000025679.11
OTU domain, ubiquitin aldehyde binding 1
chr17_-_25973288 0.96 ENSMUST00000075884.8
ENSMUST00000238120.2
ENSMUST00000236137.2
ENSMUST00000237359.2
mesothelin
chr15_+_68800261 0.95 ENSMUST00000022954.7
KH domain containing, RNA binding, signal transduction associated 3
chr9_+_94551929 0.92 ENSMUST00000033463.10
solute carrier family 9 (sodium/hydrogen exchanger), member 9
chr15_+_34238174 0.89 ENSMUST00000022867.5
ENSMUST00000226627.2
lysosomal-associated protein transmembrane 4B
chr16_-_94171533 0.88 ENSMUST00000113910.8
phosphatidylinositol glycan anchor biosynthesis, class P
chr4_+_43441939 0.88 ENSMUST00000060864.13
testis specific protein kinase 1
chr7_+_44146029 0.88 ENSMUST00000205359.2
family with sequence similarity 71, member E1
chr1_-_164281344 0.87 ENSMUST00000193367.2
ATPase, Na+/K+ transporting, beta 1 polypeptide
chr7_-_114235506 0.84 ENSMUST00000205714.2
ENSMUST00000206853.2
ENSMUST00000205933.2
ENSMUST00000206156.2
ENSMUST00000032907.9
ENSMUST00000032906.11
calcitonin/calcitonin-related polypeptide, alpha
chr17_-_14914484 0.82 ENSMUST00000170872.3
thrombospondin 2
chr1_+_33947250 0.81 ENSMUST00000183034.5
dystonin
chr1_-_58625350 0.81 ENSMUST00000038372.14
ENSMUST00000097724.10
family with sequence similarity 126, member B
chr7_+_43361930 0.81 ENSMUST00000066834.8
kallikrein related-peptidase 13
chr6_+_68247469 0.80 ENSMUST00000103321.3
immunoglobulin kappa variable 1-110
chr2_+_103858066 0.80 ENSMUST00000028603.10
F-box protein 3
chr1_-_92401459 0.79 ENSMUST00000185251.2
ENSMUST00000027478.7
NADH:ubiquinone oxidoreductase subunit A10
chr7_-_138447933 0.77 ENSMUST00000118810.2
ENSMUST00000075667.5
ENSMUST00000119664.2
mitogen-activated protein kinase 1 interacting protein 1
chr19_+_43741431 0.77 ENSMUST00000026199.14
cutC copper transporter
chr7_+_138968988 0.77 ENSMUST00000106098.8
ENSMUST00000026550.14
inositol polyphosphate-5-phosphatase A
chr10_+_39488930 0.76 ENSMUST00000019987.7
TRAF3 interacting protein 2
chr16_-_94171340 0.75 ENSMUST00000138514.2
phosphatidylinositol glycan anchor biosynthesis, class P
chr8_+_95113066 0.75 ENSMUST00000161576.8
ENSMUST00000034220.8
homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
chr4_-_151129020 0.74 ENSMUST00000103204.11
period circadian clock 3
chr19_+_43741513 0.73 ENSMUST00000112047.10
cutC copper transporter
chr15_+_25910510 0.73 ENSMUST00000228600.2
reticulophagy regulator 1
chr6_+_67873135 0.72 ENSMUST00000103310.3
immunoglobulin kappa variable 14-126
chr16_-_94171556 0.71 ENSMUST00000113906.9
phosphatidylinositol glycan anchor biosynthesis, class P
chr7_-_44145830 0.71 ENSMUST00000118515.9
ENSMUST00000138328.3
ENSMUST00000239015.2
ENSMUST00000118808.9
ER membrane protein complex subunit 10
chr10_-_43934774 0.69 ENSMUST00000239010.2
crystallin beta-gamma domain containing 1
chr11_+_69214895 0.69 ENSMUST00000060956.13
trafficking protein particle complex 1
chr2_+_3514071 0.68 ENSMUST00000036350.3
cerebral dopamine neurotrophic factor
chr17_+_44112679 0.67 ENSMUST00000229744.2
regulator of calcineurin 2
chr10_-_128657445 0.67 ENSMUST00000217685.2
ENSMUST00000026409.5
ENSMUST00000219215.2
ENSMUST00000219524.2
ORM1-like 2 (S. cerevisiae)
chr7_-_133384449 0.65 ENSMUST00000063669.8
DEAH (Asp-Glu-Ala-His) box polypeptide 32
chr19_-_57170725 0.64 ENSMUST00000133369.2
actin-binding LIM protein 1
chr4_-_115911053 0.63 ENSMUST00000030475.3
NOL1/NOP2/Sun domain family, member 4
chr17_+_34863738 0.63 ENSMUST00000036720.9
FK506 binding protein-like
chr8_-_91860576 0.63 ENSMUST00000120213.9
ENSMUST00000109609.9
AKT interacting protein
chr2_+_132689640 0.62 ENSMUST00000124836.8
ENSMUST00000154160.2
cardiolipin synthase 1
chr3_-_75177378 0.62 ENSMUST00000039047.5
serine (or cysteine) peptidase inhibitor, clade I, member 2
chr11_+_110888313 0.62 ENSMUST00000106635.2
potassium inwardly-rectifying channel, subfamily J, member 16
chr11_-_58425662 0.60 ENSMUST00000213188.3
olfactory receptor 330
chr16_-_33916354 0.60 ENSMUST00000114973.9
ENSMUST00000232157.2
ENSMUST00000114964.8
kalirin, RhoGEF kinase
chr4_-_119395966 0.59 ENSMUST00000079611.13
FSHD region gene 2 family member 1
chr3_-_142101339 0.59 ENSMUST00000198381.5
ENSMUST00000090134.12
ENSMUST00000196908.5
PDZ and LIM domain 5
chr4_+_40269563 0.58 ENSMUST00000129758.3
small integral membrane protein 27
chr19_+_28941292 0.58 ENSMUST00000045674.4
phospholipid phosphatase 6
chr11_+_98828495 0.57 ENSMUST00000107475.9
ENSMUST00000068133.10
retinoic acid receptor, alpha
chr10_+_88566918 0.57 ENSMUST00000116234.9
ADP-ribosylation factor-like 1
chr16_+_43330630 0.57 ENSMUST00000114695.3
zinc finger and BTB domain containing 20
chr17_+_28910393 0.56 ENSMUST00000124886.9
ENSMUST00000114758.9
mitogen-activated protein kinase 14
chr11_+_69214883 0.56 ENSMUST00000102601.10
trafficking protein particle complex 1
chr2_-_104324035 0.55 ENSMUST00000111124.8
homeodomain interacting protein kinase 3
chr12_-_115611981 0.55 ENSMUST00000103540.3
ENSMUST00000199266.2
immunoglobulin heavy variable V8-12
chrX_-_153999333 0.55 ENSMUST00000112551.4
spermidine/spermine N1-acetyl transferase 1
chr9_+_123921573 0.55 ENSMUST00000111442.3
ENSMUST00000171499.3
chemokine (C-C motif) receptor 5
chr7_+_130294262 0.54 ENSMUST00000033141.7
transforming, acidic coiled-coil containing protein 2
chr11_-_83959175 0.54 ENSMUST00000100705.11
dual specificity phosphatase 14
chr6_-_97436223 0.54 ENSMUST00000113359.8
FERM domain containing 4B
chr8_-_91860655 0.53 ENSMUST00000125257.3
AKT interacting protein
chr17_-_15784582 0.52 ENSMUST00000147532.8
PR domain containing 9
chr1_+_171173252 0.50 ENSMUST00000006579.5
prefoldin 2

Network of associatons between targets according to the STRING database.

First level regulatory network of Hlf

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
7.0 21.0 GO:0097037 heme export(GO:0097037)
2.8 16.8 GO:1902998 regulation of neuronal signal transduction(GO:1902847) positive regulation of neurofibrillary tangle assembly(GO:1902998)
2.1 6.2 GO:0018879 biphenyl metabolic process(GO:0018879)
1.8 5.5 GO:2000487 asparagine transport(GO:0006867) positive regulation of glutamine transport(GO:2000487)
1.8 5.5 GO:0009087 methionine catabolic process(GO:0009087)
1.4 5.5 GO:0015851 nucleobase transport(GO:0015851) pyrimidine nucleobase transport(GO:0015855)
1.2 6.2 GO:1904721 regulation of mRNA cleavage(GO:0031437) negative regulation of mRNA cleavage(GO:0031438) regulation of mRNA endonucleolytic cleavage involved in unfolded protein response(GO:1904720) negative regulation of mRNA endonucleolytic cleavage involved in unfolded protein response(GO:1904721)
1.2 39.4 GO:0035634 response to stilbenoid(GO:0035634)
1.0 3.1 GO:0031104 dendrite regeneration(GO:0031104)
1.0 4.1 GO:0034757 negative regulation of iron ion transport(GO:0034757) negative regulation of iron ion transmembrane transport(GO:0034760)
0.9 2.8 GO:0046710 GDP metabolic process(GO:0046710)
0.9 3.7 GO:0010982 GPI anchor release(GO:0006507) regulation of high-density lipoprotein particle clearance(GO:0010982)
0.9 2.7 GO:0042822 pyridoxal phosphate metabolic process(GO:0042822)
0.7 6.7 GO:0006572 tyrosine catabolic process(GO:0006572)
0.7 2.1 GO:0071288 cellular response to mercury ion(GO:0071288)
0.7 2.7 GO:0042851 L-alanine metabolic process(GO:0042851)
0.6 1.7 GO:0002426 immunoglobulin production in mucosal tissue(GO:0002426)
0.6 30.8 GO:0007339 binding of sperm to zona pellucida(GO:0007339)
0.6 9.6 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.5 3.6 GO:1901475 pyruvate transmembrane transport(GO:1901475)
0.5 1.5 GO:0006553 lysine metabolic process(GO:0006553)
0.5 4.4 GO:0060763 mammary duct terminal end bud growth(GO:0060763)
0.5 1.4 GO:0046294 formaldehyde catabolic process(GO:0046294)
0.5 4.2 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
0.5 13.6 GO:0019373 epoxygenase P450 pathway(GO:0019373)
0.4 4.7 GO:0000255 allantoin metabolic process(GO:0000255)
0.4 12.8 GO:0015721 bile acid and bile salt transport(GO:0015721)
0.4 2.4 GO:0034334 adherens junction maintenance(GO:0034334)
0.4 1.6 GO:2000312 regulation of kainate selective glutamate receptor activity(GO:2000312)
0.4 5.3 GO:0015747 urate transport(GO:0015747)
0.3 4.1 GO:0046485 ether lipid metabolic process(GO:0046485)
0.3 2.1 GO:0016259 selenocysteine metabolic process(GO:0016259)
0.3 0.9 GO:1903281 positive regulation of calcium:sodium antiporter activity(GO:1903281)
0.3 0.8 GO:0001983 baroreceptor response to increased systemic arterial blood pressure(GO:0001983)
0.3 1.1 GO:0010609 mRNA localization resulting in posttranscriptional regulation of gene expression(GO:0010609)
0.2 3.2 GO:0010898 positive regulation of triglyceride catabolic process(GO:0010898)
0.2 2.7 GO:0044539 long-chain fatty acid import(GO:0044539)
0.2 2.2 GO:0042905 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.2 9.5 GO:0006767 water-soluble vitamin metabolic process(GO:0006767)
0.2 1.6 GO:0071630 nucleus-associated proteasomal ubiquitin-dependent protein catabolic process(GO:0071630)
0.2 1.6 GO:0006777 Mo-molybdopterin cofactor biosynthetic process(GO:0006777) Mo-molybdopterin cofactor metabolic process(GO:0019720)
0.2 1.0 GO:1903774 positive regulation of viral budding via host ESCRT complex(GO:1903774)
0.2 0.6 GO:0060010 Sertoli cell fate commitment(GO:0060010)
0.2 1.7 GO:0097501 stress response to metal ion(GO:0097501)
0.2 0.5 GO:0010845 positive regulation of reciprocal meiotic recombination(GO:0010845)
0.2 2.1 GO:0006551 leucine metabolic process(GO:0006551)
0.2 2.7 GO:0006995 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.2 0.7 GO:0090155 negative regulation of sphingolipid biosynthetic process(GO:0090155) cellular sphingolipid homeostasis(GO:0090156) negative regulation of ceramide biosynthetic process(GO:1900060)
0.2 1.0 GO:0071677 positive regulation of mononuclear cell migration(GO:0071677)
0.2 1.1 GO:0070495 regulation of thrombin receptor signaling pathway(GO:0070494) negative regulation of thrombin receptor signaling pathway(GO:0070495)
0.1 1.5 GO:0019336 phenol-containing compound catabolic process(GO:0019336)
0.1 0.4 GO:0000715 nucleotide-excision repair, DNA damage recognition(GO:0000715)
0.1 11.0 GO:0007566 embryo implantation(GO:0007566)
0.1 4.1 GO:1901741 positive regulation of myoblast fusion(GO:1901741)
0.1 0.8 GO:1903071 positive regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903071)
0.1 0.5 GO:1902037 negative regulation of hematopoietic stem cell differentiation(GO:1902037)
0.1 0.6 GO:0032918 polyamine acetylation(GO:0032917) spermidine acetylation(GO:0032918)
0.1 0.6 GO:0060139 positive regulation by symbiont of host apoptotic process(GO:0052151) positive regulation of apoptotic process by virus(GO:0060139)
0.1 0.3 GO:0046168 glycerol-3-phosphate catabolic process(GO:0046168)
0.1 0.3 GO:1902527 positive regulation of protein monoubiquitination(GO:1902527)
0.1 0.7 GO:0002003 angiotensin maturation(GO:0002003)
0.1 0.6 GO:0042256 mature ribosome assembly(GO:0042256)
0.1 6.3 GO:1900047 negative regulation of blood coagulation(GO:0030195) negative regulation of hemostasis(GO:1900047)
0.1 0.5 GO:0072338 creatinine metabolic process(GO:0046449) cellular lactam metabolic process(GO:0072338)
0.1 0.3 GO:0071726 response to diacyl bacterial lipopeptide(GO:0071724) cellular response to diacyl bacterial lipopeptide(GO:0071726)
0.1 0.9 GO:1990118 sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.1 0.7 GO:0061709 reticulophagy(GO:0061709)
0.1 6.0 GO:0042771 intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:0042771)
0.1 0.6 GO:0061366 behavioral response to chemical pain(GO:0061366) behavioral response to formalin induced pain(GO:0061368)
0.1 2.3 GO:0072311 renal filtration cell differentiation(GO:0061318) glomerular visceral epithelial cell differentiation(GO:0072112) glomerular epithelial cell differentiation(GO:0072311)
0.1 0.4 GO:0006384 transcription initiation from RNA polymerase III promoter(GO:0006384)
0.1 0.6 GO:0031584 activation of phospholipase D activity(GO:0031584)
0.1 2.0 GO:0071108 protein K48-linked deubiquitination(GO:0071108)
0.1 2.7 GO:0006953 acute-phase response(GO:0006953)
0.0 0.8 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.0 1.5 GO:0009303 rRNA transcription(GO:0009303)
0.0 4.6 GO:0035383 acyl-CoA metabolic process(GO:0006637) thioester metabolic process(GO:0035383)
0.0 0.1 GO:0006701 progesterone biosynthetic process(GO:0006701)
0.0 2.0 GO:0006505 GPI anchor metabolic process(GO:0006505)
0.0 0.2 GO:0097167 circadian regulation of translation(GO:0097167)
0.0 0.2 GO:1900227 positive regulation of NLRP3 inflammasome complex assembly(GO:1900227)
0.0 0.6 GO:0043508 negative regulation of JUN kinase activity(GO:0043508)
0.0 0.4 GO:0031573 intra-S DNA damage checkpoint(GO:0031573)
0.0 0.8 GO:0046855 inositol phosphate dephosphorylation(GO:0046855)
0.0 0.5 GO:0006620 posttranslational protein targeting to membrane(GO:0006620)
0.0 2.7 GO:0006749 glutathione metabolic process(GO:0006749)
0.0 0.8 GO:0008090 retrograde axonal transport(GO:0008090)
0.0 0.5 GO:0042407 cristae formation(GO:0042407)
0.0 1.0 GO:0061462 protein localization to lysosome(GO:0061462)
0.0 0.3 GO:0006983 ER overload response(GO:0006983)
0.0 0.6 GO:0097066 response to thyroid hormone(GO:0097066)
0.0 0.3 GO:0035589 G-protein coupled purinergic nucleotide receptor signaling pathway(GO:0035589)
0.0 0.6 GO:0046069 cGMP catabolic process(GO:0046069)
0.0 0.7 GO:0007614 short-term memory(GO:0007614)
0.0 0.2 GO:0000821 regulation of arginine metabolic process(GO:0000821)
0.0 0.2 GO:0042427 serotonin biosynthetic process(GO:0042427) primary amino compound biosynthetic process(GO:1901162)
0.0 0.4 GO:0006824 cobalt ion transport(GO:0006824)
0.0 0.2 GO:0070417 cellular response to cold(GO:0070417)
0.0 0.1 GO:2000503 positive regulation of natural killer cell chemotaxis(GO:2000503)
0.0 1.2 GO:0045022 early endosome to late endosome transport(GO:0045022)
0.0 0.5 GO:0022027 interkinetic nuclear migration(GO:0022027) astral microtubule organization(GO:0030953)
0.0 0.8 GO:0048305 immunoglobulin secretion(GO:0048305)
0.0 0.5 GO:0034063 stress granule assembly(GO:0034063)
0.0 1.8 GO:0051865 protein autoubiquitination(GO:0051865)
0.0 0.2 GO:0070475 rRNA base methylation(GO:0070475)
0.0 0.4 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.0 0.4 GO:0035414 negative regulation of catenin import into nucleus(GO:0035414)
0.0 0.7 GO:0045187 regulation of circadian sleep/wake cycle, sleep(GO:0045187)
0.0 0.5 GO:0071480 cellular response to gamma radiation(GO:0071480)
0.0 1.2 GO:0071300 cellular response to retinoic acid(GO:0071300)
0.0 1.0 GO:0033120 positive regulation of RNA splicing(GO:0033120)
0.0 0.2 GO:0048280 vesicle fusion with Golgi apparatus(GO:0048280)
0.0 1.0 GO:2001243 negative regulation of intrinsic apoptotic signaling pathway(GO:2001243)
0.0 0.7 GO:0071542 dopaminergic neuron differentiation(GO:0071542)
0.0 0.5 GO:0090162 establishment of epithelial cell polarity(GO:0090162)
0.0 0.2 GO:0060391 positive regulation of SMAD protein import into nucleus(GO:0060391)
0.0 0.3 GO:0007194 negative regulation of adenylate cyclase activity(GO:0007194) negative regulation of cyclase activity(GO:0031280)
0.0 0.1 GO:0014045 establishment of endothelial blood-brain barrier(GO:0014045)
0.0 1.6 GO:0006910 phagocytosis, recognition(GO:0006910) complement activation, classical pathway(GO:0006958)
0.0 0.0 GO:0015881 creatine transport(GO:0015881)
0.0 0.0 GO:0047484 regulation of response to osmotic stress(GO:0047484)
0.0 0.1 GO:0051694 pointed-end actin filament capping(GO:0051694)
0.0 0.1 GO:0043353 enucleate erythrocyte differentiation(GO:0043353)
0.0 1.3 GO:0031638 zymogen activation(GO:0031638)
0.0 1.6 GO:0046330 positive regulation of JNK cascade(GO:0046330)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
7.0 21.0 GO:0061474 phagolysosome membrane(GO:0061474)
1.6 4.7 GO:0070195 growth hormone receptor complex(GO:0070195)
1.1 16.8 GO:0034366 spherical high-density lipoprotein particle(GO:0034366)
1.0 4.8 GO:0098560 cytoplasmic side of late endosome membrane(GO:0098560)
0.6 15.2 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.5 1.6 GO:0019008 molybdopterin synthase complex(GO:0019008)
0.3 3.1 GO:0031265 CD95 death-inducing signaling complex(GO:0031265)
0.2 2.1 GO:0005577 fibrinogen complex(GO:0005577)
0.2 0.8 GO:1990037 Lewy body core(GO:1990037)
0.2 2.7 GO:0044754 autolysosome(GO:0044754)
0.2 15.6 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.2 1.2 GO:0070695 FHF complex(GO:0070695)
0.1 0.7 GO:0035339 SPOTS complex(GO:0035339)
0.1 1.1 GO:0045293 mRNA editing complex(GO:0045293)
0.1 2.4 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.1 1.8 GO:0031983 vesicle lumen(GO:0031983)
0.1 0.5 GO:0005745 m-AAA complex(GO:0005745)
0.1 0.4 GO:0071942 XPC complex(GO:0071942)
0.1 0.8 GO:0031673 H zone(GO:0031673)
0.1 1.5 GO:0005869 dynactin complex(GO:0005869)
0.1 1.0 GO:0016272 prefoldin complex(GO:0016272)
0.1 0.4 GO:0030896 checkpoint clamp complex(GO:0030896)
0.1 0.9 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.1 2.0 GO:0030008 TRAPP complex(GO:0030008)
0.1 1.1 GO:0072546 ER membrane protein complex(GO:0072546)
0.1 4.7 GO:0016328 lateral plasma membrane(GO:0016328)
0.1 20.3 GO:0072562 blood microparticle(GO:0072562)
0.1 1.5 GO:0035102 PRC1 complex(GO:0035102)
0.1 1.9 GO:0002080 acrosomal membrane(GO:0002080)
0.1 1.0 GO:0000813 ESCRT I complex(GO:0000813)
0.1 0.3 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.1 1.6 GO:0030057 desmosome(GO:0030057)
0.1 1.3 GO:0042589 zymogen granule membrane(GO:0042589)
0.1 24.4 GO:0016323 basolateral plasma membrane(GO:0016323)
0.1 1.9 GO:0030992 intraciliary transport particle B(GO:0030992)
0.1 0.2 GO:0005879 axonemal microtubule(GO:0005879)
0.0 0.4 GO:0031313 extrinsic component of endosome membrane(GO:0031313)
0.0 9.5 GO:0031225 anchored component of membrane(GO:0031225)
0.0 0.3 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.0 2.0 GO:0030964 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 8.8 GO:0042579 peroxisome(GO:0005777) microbody(GO:0042579)
0.0 0.4 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.0 3.2 GO:0005604 basement membrane(GO:0005604)
0.0 0.1 GO:0070722 Tle3-Aes complex(GO:0070722)
0.0 35.1 GO:0005615 extracellular space(GO:0005615)
0.0 9.0 GO:0005789 endoplasmic reticulum membrane(GO:0005789)
0.0 0.1 GO:0090571 RNA polymerase II transcription repressor complex(GO:0090571)
0.0 3.6 GO:0000139 Golgi membrane(GO:0000139)
0.0 1.8 GO:0043296 apical junction complex(GO:0043296)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.8 14.0 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
1.6 4.7 GO:0004903 growth hormone receptor activity(GO:0004903)
1.4 30.8 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
1.4 9.6 GO:0001851 complement component C3b binding(GO:0001851)
1.4 4.1 GO:0050479 glyceryl-ether monooxygenase activity(GO:0050479)
1.4 5.5 GO:0015182 L-asparagine transmembrane transporter activity(GO:0015182)
1.4 5.5 GO:0004478 methionine adenosyltransferase activity(GO:0004478)
1.1 5.5 GO:0015205 purine nucleobase transmembrane transporter activity(GO:0005345) pyrimidine nucleobase transmembrane transporter activity(GO:0005350) nucleobase transmembrane transporter activity(GO:0015205) glycerol channel activity(GO:0015254)
1.0 6.2 GO:0060698 endoribonuclease inhibitor activity(GO:0060698)
1.0 37.8 GO:0008392 arachidonic acid epoxygenase activity(GO:0008392)
0.9 2.8 GO:0044715 8-oxo-dGDP phosphatase activity(GO:0044715)
0.9 2.7 GO:0070279 vitamin B6 binding(GO:0070279)
0.8 3.1 GO:0043120 tumor necrosis factor binding(GO:0043120)
0.7 2.1 GO:0004756 selenide, water dikinase activity(GO:0004756) phosphotransferase activity, paired acceptors(GO:0016781)
0.6 16.8 GO:0051787 misfolded protein binding(GO:0051787)
0.6 4.1 GO:0004556 alpha-amylase activity(GO:0004556)
0.5 2.7 GO:0047635 L-alanine:2-oxoglutarate aminotransferase activity(GO:0004021) alanine-oxo-acid transaminase activity(GO:0047635)
0.5 2.7 GO:0043758 acetate-CoA ligase (ADP-forming) activity(GO:0043758)
0.5 3.2 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
0.5 3.6 GO:0050833 pyruvate transmembrane transporter activity(GO:0050833)
0.5 4.6 GO:0016812 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides(GO:0016812)
0.4 3.7 GO:0004630 phospholipase D activity(GO:0004630)
0.4 2.3 GO:0008970 phosphatidylcholine 1-acylhydrolase activity(GO:0008970)
0.4 11.0 GO:0043295 glutathione binding(GO:0043295) oligopeptide binding(GO:1900750)
0.4 1.5 GO:0004800 thyroxine 5'-deiodinase activity(GO:0004800)
0.3 5.3 GO:0015143 urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.3 4.9 GO:0004806 triglyceride lipase activity(GO:0004806)
0.3 2.0 GO:0019784 NEDD8-specific protease activity(GO:0019784)
0.3 1.1 GO:0005008 hepatocyte growth factor-activated receptor activity(GO:0005008)
0.3 10.5 GO:0042056 chemoattractant activity(GO:0042056)
0.2 1.5 GO:0016647 oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor(GO:0016647)
0.2 2.7 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.2 1.4 GO:0004022 alcohol dehydrogenase (NAD) activity(GO:0004022)
0.2 9.6 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.2 7.6 GO:0047617 acyl-CoA hydrolase activity(GO:0047617)
0.2 23.7 GO:0004869 cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.2 2.1 GO:0045340 mercury ion binding(GO:0045340)
0.2 4.2 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.2 6.7 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.2 0.6 GO:0009383 rRNA (cytosine-C5-)-methyltransferase activity(GO:0009383)
0.2 2.4 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.2 2.0 GO:0030976 thiamine pyrophosphate binding(GO:0030976)
0.2 2.2 GO:0001758 retinal dehydrogenase activity(GO:0001758)
0.1 7.1 GO:0008028 monocarboxylic acid transmembrane transporter activity(GO:0008028)
0.1 0.6 GO:0019809 spermidine binding(GO:0019809)
0.1 0.4 GO:0008107 galactoside 2-alpha-L-fucosyltransferase activity(GO:0008107) alpha-(1,2)-fucosyltransferase activity(GO:0031127)
0.1 0.4 GO:0015087 cobalt ion transmembrane transporter activity(GO:0015087)
0.1 1.6 GO:0016783 sulfurtransferase activity(GO:0016783)
0.1 0.2 GO:0016434 rRNA (cytosine) methyltransferase activity(GO:0016434)
0.1 0.9 GO:0015386 potassium:proton antiporter activity(GO:0015386)
0.1 2.1 GO:0003995 acyl-CoA dehydrogenase activity(GO:0003995)
0.1 0.7 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.1 0.9 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
0.1 1.2 GO:0003854 3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854)
0.1 0.2 GO:0004510 tryptophan 5-monooxygenase activity(GO:0004510)
0.1 1.8 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.1 0.2 GO:0070052 collagen V binding(GO:0070052)
0.1 0.3 GO:0004367 glycerol-3-phosphate dehydrogenase [NAD+] activity(GO:0004367)
0.1 2.0 GO:0008137 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.1 0.8 GO:0042731 PH domain binding(GO:0042731)
0.1 0.8 GO:0051525 NFAT protein binding(GO:0051525)
0.1 0.2 GO:0019862 IgA binding(GO:0019862)
0.1 4.2 GO:0005507 copper ion binding(GO:0005507)
0.1 0.6 GO:0004117 calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117) calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.0 2.1 GO:0003785 actin monomer binding(GO:0003785)
0.0 1.7 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.3 GO:0071723 lipopeptide binding(GO:0071723)
0.0 0.3 GO:0004969 histamine receptor activity(GO:0004969)
0.0 0.6 GO:0019957 C-C chemokine binding(GO:0019957)
0.0 1.4 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.0 0.6 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.0 2.0 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 3.7 GO:0030971 receptor tyrosine kinase binding(GO:0030971)
0.0 0.5 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0 3.0 GO:0035064 methylated histone binding(GO:0035064)
0.0 0.2 GO:0035614 snRNA stem-loop binding(GO:0035614)
0.0 4.4 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.5 GO:0030274 LIM domain binding(GO:0030274)
0.0 1.5 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 0.4 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.0 1.0 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.0 0.1 GO:0031726 CCR1 chemokine receptor binding(GO:0031726)
0.0 0.5 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.0 0.6 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.0 0.6 GO:0016780 phosphotransferase activity, for other substituted phosphate groups(GO:0016780)
0.0 0.6 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0 0.1 GO:0001226 RNA polymerase II transcription corepressor binding(GO:0001226)
0.0 0.3 GO:0045028 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.0 1.6 GO:0003727 single-stranded RNA binding(GO:0003727)
0.0 0.2 GO:0015174 basic amino acid transmembrane transporter activity(GO:0015174)
0.0 1.6 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.0 1.8 GO:0008565 protein transporter activity(GO:0008565)
0.0 0.1 GO:0048039 ubiquinone binding(GO:0048039)
0.0 0.1 GO:0001594 trace-amine receptor activity(GO:0001594)
0.0 4.3 GO:0061630 ubiquitin protein ligase activity(GO:0061630)
0.0 1.3 GO:0048306 calcium-dependent protein binding(GO:0048306)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 7.5 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.2 3.1 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.1 15.3 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.1 5.8 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.1 5.0 PID AMB2 NEUTROPHILS PATHWAY amb2 Integrin signaling
0.1 4.8 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.1 3.5 PID SYNDECAN 1 PATHWAY Syndecan-1-mediated signaling events
0.1 13.5 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.1 0.8 PID NFKAPPAB ATYPICAL PATHWAY Atypical NF-kappaB pathway
0.0 1.8 PID IL23 PATHWAY IL23-mediated signaling events
0.0 0.8 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.0 0.6 PID ARF6 DOWNSTREAM PATHWAY Arf6 downstream pathway
0.0 0.6 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.0 0.4 PID NETRIN PATHWAY Netrin-mediated signaling events
0.0 0.6 PID RETINOIC ACID PATHWAY Retinoic acid receptors-mediated signaling
0.0 0.4 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.0 0.7 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.0 2.5 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 14.0 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.7 9.6 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.3 17.4 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.3 4.5 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.3 7.2 REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
0.3 39.9 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.2 5.5 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.2 3.1 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.2 0.6 REACTOME BINDING AND ENTRY OF HIV VIRION Genes involved in Binding and entry of HIV virion
0.2 3.1 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.2 4.7 REACTOME PROLACTIN RECEPTOR SIGNALING Genes involved in Prolactin receptor signaling
0.2 6.2 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.1 2.7 REACTOME ALPHA LINOLENIC ACID ALA METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.1 5.7 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.1 2.1 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.1 2.4 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.1 1.6 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.1 1.0 REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
0.1 1.7 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.1 0.8 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.1 4.2 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.0 0.6 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.0 2.2 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 3.5 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.0 0.9 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.0 1.7 REACTOME REGULATION OF MRNA STABILITY BY PROTEINS THAT BIND AU RICH ELEMENTS Genes involved in Regulation of mRNA Stability by Proteins that Bind AU-rich Elements
0.0 0.9 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 0.8 REACTOME AMYLOIDS Genes involved in Amyloids
0.0 2.4 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 5.4 REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES Genes involved in Metabolism of amino acids and derivatives
0.0 0.8 REACTOME ACTIVATION OF GENES BY ATF4 Genes involved in Activation of Genes by ATF4
0.0 0.6 REACTOME ACYL CHAIN REMODELLING OF PG Genes involved in Acyl chain remodelling of PG
0.0 2.0 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.0 1.0 REACTOME PREFOLDIN MEDIATED TRANSFER OF SUBSTRATE TO CCT TRIC Genes involved in Prefoldin mediated transfer of substrate to CCT/TriC
0.0 1.1 REACTOME SEMA4D IN SEMAPHORIN SIGNALING Genes involved in Sema4D in semaphorin signaling
0.0 0.3 REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1 Genes involved in IKK complex recruitment mediated by RIP1
0.0 0.4 REACTOME GRB2 EVENTS IN ERBB2 SIGNALING Genes involved in GRB2 events in ERBB2 signaling
0.0 0.4 REACTOME FORMATION OF INCISION COMPLEX IN GG NER Genes involved in Formation of incision complex in GG-NER
0.0 0.4 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0 0.6 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.0 0.3 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.0 0.4 REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 3 PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter
0.0 0.3 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.0 0.7 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.0 0.4 REACTOME GLYCOLYSIS Genes involved in Glycolysis