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GSE58827: Dynamics of the Mouse Liver

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Results for Hnf1b

Z-value: 2.85

Motif logo

Transcription factors associated with Hnf1b

Gene Symbol Gene ID Gene Info
ENSMUSG00000020679.12 HNF1 homeobox B

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Hnf1bmm39_v1_chr11_+_83741657_837416810.316.7e-02Click!

Activity profile of Hnf1b motif

Sorted Z-values of Hnf1b motif

Promoter Log-likelihood Transcript Gene Gene Info
chr5_-_89605622 39.87 ENSMUST00000049209.13
vitamin D binding protein
chr1_-_130589321 30.55 ENSMUST00000137276.3
complement component 4 binding protein
chr1_-_130589349 30.40 ENSMUST00000027657.14
complement component 4 binding protein
chr2_-_134396268 27.76 ENSMUST00000028704.3
hydroxyacid oxidase 1, liver
chr19_+_30210320 27.19 ENSMUST00000025797.7
mannose-binding lectin (protein C) 2
chr16_+_22769822 27.07 ENSMUST00000023590.9
histidine-rich glycoprotein
chr1_+_88139678 26.77 ENSMUST00000073049.7
UDP glucuronosyltransferase 1 family, polypeptide A1
chr16_+_22769844 26.73 ENSMUST00000232422.2
histidine-rich glycoprotein
chr11_+_101258368 25.91 ENSMUST00000019469.3
glucose-6-phosphatase, catalytic
chr10_-_95678786 25.17 ENSMUST00000211096.2
predicted gene, 33543
chr5_-_87240405 24.20 ENSMUST00000132667.2
ENSMUST00000145617.8
ENSMUST00000094649.11
UDP glucuronosyltransferase 2 family, polypeptide B36
chr13_-_24098981 24.03 ENSMUST00000110407.4
solute carrier family 17 (sodium phosphate), member 4
chr9_-_48516447 23.92 ENSMUST00000034808.12
ENSMUST00000119426.2
nicotinamide N-methyltransferase
chr5_+_90666791 22.63 ENSMUST00000113179.9
ENSMUST00000128740.2
afamin
chr13_-_24098951 22.46 ENSMUST00000021769.16
solute carrier family 17 (sodium phosphate), member 4
chr1_+_87983099 22.42 ENSMUST00000138182.8
ENSMUST00000113142.10
UDP glycosyltransferase 1 family, polypeptide A10
chr13_+_23991010 21.45 ENSMUST00000006786.11
ENSMUST00000099697.3
solute carrier family 17 (sodium phosphate), member 2
chr1_+_87998487 21.20 ENSMUST00000073772.5
UDP glucuronosyltransferase 1 family, polypeptide A9
chr13_-_4329421 19.86 ENSMUST00000021632.5
aldo-keto reductase family 1, member C12
chr1_+_88093726 19.69 ENSMUST00000097659.5
UDP glucuronosyltransferase 1 family, polypeptide A5
chr1_+_87983189 18.69 ENSMUST00000173325.2
UDP glycosyltransferase 1 family, polypeptide A10
chr5_-_87485023 17.76 ENSMUST00000031195.3
UDP glucuronosyltransferase 2 family, polypeptide A3
chr3_+_129630380 17.16 ENSMUST00000077918.7
complement component factor i
chr11_-_84058292 16.59 ENSMUST00000050771.8
predicted gene 11437
chr5_-_87716882 16.49 ENSMUST00000113314.3
sulfotransferase family 1D, member 1
chr2_-_34990689 16.47 ENSMUST00000226631.2
ENSMUST00000045776.5
ENSMUST00000226972.2
expressed sequence AI182371
chr1_+_88066086 16.28 ENSMUST00000014263.6
UDP glucuronosyltransferase 1 family, polypeptide A6A
chr17_+_12597490 16.22 ENSMUST00000014578.7
plasminogen
chr19_-_8382424 15.20 ENSMUST00000064507.12
ENSMUST00000120540.2
ENSMUST00000096269.11
solute carrier family 22, member 30
chr15_+_10216041 15.15 ENSMUST00000130720.8
prolactin receptor
chr10_-_95678748 14.54 ENSMUST00000210336.2
predicted gene, 33543
chr16_-_56984137 14.24 ENSMUST00000231733.2
nitrilase family, member 2
chr19_-_46661321 14.19 ENSMUST00000026012.8
cytochrome P450, family 17, subfamily a, polypeptide 1
chr13_+_4241149 13.72 ENSMUST00000021634.4
aldo-keto reductase family 1, member C13
chr2_-_34951443 13.69 ENSMUST00000028233.7
hemolytic complement
chr19_-_46661501 13.66 ENSMUST00000236174.2
cytochrome P450, family 17, subfamily a, polypeptide 1
chr4_-_108002186 13.56 ENSMUST00000130776.2
sterol carrier protein 2, liver
chr5_+_90608751 13.51 ENSMUST00000031314.10
albumin
chr7_+_51537645 13.42 ENSMUST00000208711.2
growth arrest specific 2
chr13_+_93810911 13.40 ENSMUST00000048001.8
dimethylglycine dehydrogenase precursor
chr5_-_87682972 13.37 ENSMUST00000120150.2
sulfotransferase family 1B, member 1
chr15_+_100202079 12.89 ENSMUST00000230252.2
ENSMUST00000231166.2
methyltransferase like 7A1
chr6_+_90310252 12.59 ENSMUST00000046128.12
ENSMUST00000164761.6
urocanase domain containing 1
chr15_+_100202061 12.29 ENSMUST00000229574.2
ENSMUST00000229217.2
methyltransferase like 7A1
chr4_+_138694422 12.12 ENSMUST00000116094.5
ENSMUST00000239443.2
ring finger protein 186
chr15_+_100202021 11.65 ENSMUST00000230472.2
methyltransferase like 7A1
chr9_-_71070506 11.57 ENSMUST00000074465.9
aquaporin 9
chr13_+_4283729 11.44 ENSMUST00000081326.7
aldo-keto reductase family 1, member C19
chr13_+_24023428 11.02 ENSMUST00000091698.12
ENSMUST00000110422.3
ENSMUST00000166467.9
solute carrier family 17 (sodium phosphate), member 3
chr11_-_11848107 10.37 ENSMUST00000178704.8
dopa decarboxylase
chr4_+_150938376 10.27 ENSMUST00000073600.9
ERBB receptor feedback inhibitor 1
chr19_+_43770619 10.03 ENSMUST00000026208.6
ATP-binding cassette, sub-family C (CFTR/MRP), member 2
chr10_-_89369432 9.96 ENSMUST00000105297.2
nuclear receptor subfamily 1, group H, member 4
chr11_-_11848044 9.55 ENSMUST00000066237.10
dopa decarboxylase
chr13_-_93810808 9.42 ENSMUST00000015941.8
betaine-homocysteine methyltransferase 2
chr5_-_108823435 9.35 ENSMUST00000051757.14
solute carrier family 26 (sulfate transporter), member 1
chr11_+_70410445 9.34 ENSMUST00000179000.2
glycolipid transfer protein domain containing 2
chr11_+_108286114 9.17 ENSMUST00000000049.6
apolipoprotein H
chr11_+_78356523 9.11 ENSMUST00000001126.4
solute carrier family 46, member 1
chr10_+_62897353 9.08 ENSMUST00000178684.3
ENSMUST00000020266.15
phenazine biosynthesis-like protein domain containing 1
chr3_-_137837117 8.98 ENSMUST00000029805.13
microsomal triglyceride transfer protein
chr13_+_24023386 8.95 ENSMUST00000039721.14
solute carrier family 17 (sodium phosphate), member 3
chr2_+_162829250 8.34 ENSMUST00000018012.14
serum/glucocorticoid regulated kinase 2
chr10_-_125225298 8.31 ENSMUST00000210780.2
solute carrier family 16 (monocarboxylic acid transporters), member 7
chr2_+_163389068 8.14 ENSMUST00000109411.8
ENSMUST00000018094.13
hepatic nuclear factor 4, alpha
chr7_-_44753168 7.88 ENSMUST00000211085.2
ENSMUST00000210642.2
ENSMUST00000003512.9
Fc fragment of IgG receptor and transporter
chr1_+_180878797 7.77 ENSMUST00000036819.7
RIKEN cDNA 9130409I23 gene
chr4_-_6275629 7.70 ENSMUST00000029905.2
cytochrome P450, family 7, subfamily a, polypeptide 1
chr2_+_162829422 7.57 ENSMUST00000117123.2
serum/glucocorticoid regulated kinase 2
chr11_+_114566257 7.34 ENSMUST00000045779.6
tweety family member 2
chr18_+_56533389 7.12 ENSMUST00000237355.2
ENSMUST00000237422.2
GRAM domain containing 3
chr19_+_42034231 6.93 ENSMUST00000172244.8
ENSMUST00000081714.5
4-hydroxy-2-oxoglutarate aldolase 1
chr12_+_59142439 6.89 ENSMUST00000219140.3
MIA SH3 domain ER export factor 2
chr9_-_70841881 6.84 ENSMUST00000214995.2
lipase, hepatic
chr4_+_98919183 6.79 ENSMUST00000030280.7
angiopoietin-like 3
chr4_-_140344373 6.65 ENSMUST00000154979.2
Rho guanine nucleotide exchange factor (GEF) 10-like
chr9_+_21746785 6.55 ENSMUST00000058777.8
angiopoietin-like 8
chr13_+_55300453 6.50 ENSMUST00000005452.6
fibroblast growth factor receptor 4
chr5_+_35198853 6.44 ENSMUST00000030985.10
ENSMUST00000202573.2
hepatocyte growth factor activator
chr17_-_35265514 6.38 ENSMUST00000007250.14
mutS homolog 5
chr10_+_60925130 6.27 ENSMUST00000020298.8
pterin 4 alpha carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha (TCF1) 1
chr1_+_133173826 6.23 ENSMUST00000105082.9
ENSMUST00000038295.15
pleckstrin homology domain containing, family A member 6
chr15_+_99291491 6.18 ENSMUST00000159531.3
transmembrane BAX inhibitor motif containing 6
chr10_+_60925108 5.96 ENSMUST00000218005.2
pterin 4 alpha carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha (TCF1) 1
chr7_-_127494750 5.93 ENSMUST00000033074.8
vitamin K epoxide reductase complex, subunit 1
chr1_+_171954316 5.89 ENSMUST00000075895.9
ENSMUST00000111252.4
peroxisomal biogenesis factor 19
chrX_+_100419965 5.83 ENSMUST00000119080.8
gap junction protein, beta 1
chr5_+_31454939 5.64 ENSMUST00000201675.3
glucokinase regulatory protein
chr15_+_99291455 5.63 ENSMUST00000162624.8
transmembrane BAX inhibitor motif containing 6
chr19_-_8196196 5.59 ENSMUST00000113298.9
solute carrier family 22. member 29
chr4_-_119217079 5.52 ENSMUST00000143494.3
ENSMUST00000154606.9
coiled-coil domain containing 30
chr19_+_56276375 5.31 ENSMUST00000166049.8
hyaluronic acid binding protein 2
chr10_+_4561974 5.29 ENSMUST00000105590.8
ENSMUST00000067086.14
estrogen receptor 1 (alpha)
chr1_-_20688196 5.23 ENSMUST00000088448.12
polycystic kidney and hepatic disease 1
chr5_-_87054796 5.22 ENSMUST00000031181.16
ENSMUST00000113333.2
UDP glucuronosyltransferase 2 family, polypeptide B34
chr12_-_25147139 4.95 ENSMUST00000221761.2
inhibitor of DNA binding 2
chr17_+_74702601 4.87 ENSMUST00000024870.9
ENSMUST00000179074.9
ENSMUST00000233799.2
ENSMUST00000233042.2
solute carrier family 30 (zinc transporter), member 6
chr11_-_73217298 4.81 ENSMUST00000155630.9
aspartoacylase
chr19_+_56276343 4.80 ENSMUST00000095948.11
hyaluronic acid binding protein 2
chr11_+_4833186 4.77 ENSMUST00000139737.2
nipsnap homolog 1
chr11_-_73217633 4.75 ENSMUST00000134079.2
aspartoacylase
chr11_+_70410009 4.75 ENSMUST00000057685.3
glycolipid transfer protein domain containing 2
chr7_-_44711771 4.74 ENSMUST00000210101.2
ENSMUST00000209219.2
proline-rich Gla (G-carboxyglutamic acid) polypeptide 2
chr10_-_8761777 4.71 ENSMUST00000015449.6
SAM and SH3 domain containing 1
chr10_-_125164399 4.58 ENSMUST00000063318.10
solute carrier family 16 (monocarboxylic acid transporters), member 7
chr5_-_38649291 4.54 ENSMUST00000129099.8
solute carrier family 2 (facilitated glucose transporter), member 9
chr15_-_50753792 4.52 ENSMUST00000185183.2
transcriptional repressor GATA binding 1
chr1_-_136888118 4.47 ENSMUST00000192357.6
ENSMUST00000027649.14
nuclear receptor subfamily 5, group A, member 2
chr4_+_48279794 4.36 ENSMUST00000030029.10
inversin
chr5_-_114582053 4.34 ENSMUST00000123256.3
ENSMUST00000112245.6
methylmalonic aciduria (cobalamin deficiency) cblB type homolog (human)
chr9_-_70842090 4.31 ENSMUST00000034731.10
lipase, hepatic
chr1_-_134289670 4.27 ENSMUST00000049470.11
transmembrane protein 183A
chr3_-_116506294 4.24 ENSMUST00000029569.9
solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member 3
chr7_-_119494669 4.18 ENSMUST00000098080.9
DCN1, defective in cullin neddylation 1, domain containing 3 (S. cerevisiae)
chr9_+_95441652 4.07 ENSMUST00000079597.7
progestin and adipoQ receptor family member IX
chr13_+_67080864 4.03 ENSMUST00000021990.4
phosphatidylserine synthase 1
chr6_-_52160816 4.01 ENSMUST00000134831.2
homeobox A3
chr5_+_31454787 3.94 ENSMUST00000201166.4
ENSMUST00000072228.9
glucokinase regulatory protein
chr3_+_154302989 3.87 ENSMUST00000140644.8
ENSMUST00000144764.8
ENSMUST00000155232.2
crystallin, zeta
chr2_+_163348728 3.87 ENSMUST00000143911.8
hepatic nuclear factor 4, alpha
chrX_-_137985960 3.76 ENSMUST00000033626.15
ENSMUST00000060824.4
serine (or cysteine) peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 7
chr12_+_76580386 3.70 ENSMUST00000219063.2
pleckstrin homology domain containing, family G (with RhoGef domain) member 3
chr3_+_90444537 3.51 ENSMUST00000098911.10
S100 calcium binding protein A16
chr7_+_119160922 3.32 ENSMUST00000130583.2
ENSMUST00000084647.13
acyl-CoA synthetase medium-chain family member 2
chrX_-_137985979 3.29 ENSMUST00000152457.2
serine (or cysteine) peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 7
chr11_+_77928736 3.15 ENSMUST00000072289.12
ENSMUST00000100784.9
ENSMUST00000073660.7
flotillin 2
chr11_-_78313043 3.11 ENSMUST00000001122.6
solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 2
chr10_-_89457115 3.11 ENSMUST00000020102.14
solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 8
chr3_-_116506345 3.02 ENSMUST00000169530.2
solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member 3
chr17_+_14087827 2.99 ENSMUST00000239324.2
afadin, adherens junction formation factor
chr1_+_133237516 2.98 ENSMUST00000094557.7
ENSMUST00000192465.2
ENSMUST00000193888.6
ENSMUST00000194044.6
ENSMUST00000184603.8
golgi transport 1A
predicted gene, 28040
predicted gene, 28040
chrM_+_2743 2.98 ENSMUST00000082392.1
mitochondrially encoded NADH dehydrogenase 1
chr3_-_113325938 2.98 ENSMUST00000132353.2
amylase 2a1
chr3_+_85946145 2.89 ENSMUST00000238331.2
SH3 domain protein D19
chr12_-_103597663 2.73 ENSMUST00000121625.2
ENSMUST00000044231.12
serine (or cysteine) peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10
chr3_-_75177378 2.71 ENSMUST00000039047.5
serine (or cysteine) peptidase inhibitor, clade I, member 2
chr16_+_43067641 2.68 ENSMUST00000079441.13
ENSMUST00000114691.8
zinc finger and BTB domain containing 20
chr4_-_150993886 2.67 ENSMUST00000128075.8
Parkinson disease (autosomal recessive, early onset) 7
chr3_+_90444613 2.63 ENSMUST00000107335.2
S100 calcium binding protein A16
chrM_+_7758 2.60 ENSMUST00000082407.1
mitochondrially encoded ATP synthase 8
chr3_-_98471301 2.52 ENSMUST00000058728.10
predicted gene 10681
chr3_-_82957104 2.44 ENSMUST00000048246.5
fibrinogen beta chain
chr8_+_96442509 2.37 ENSMUST00000034096.6
SET domain containing 6
chrX_+_139808351 2.29 ENSMUST00000033806.5
V-set and immunoglobulin domain containing 1
chr10_+_29019645 2.28 ENSMUST00000092629.4
SOGA family member 3
chrM_+_7779 2.28 ENSMUST00000082408.1
mitochondrially encoded ATP synthase 6
chr9_-_106035332 2.21 ENSMUST00000112543.9
glycerate kinase
chr1_+_58834621 2.21 ENSMUST00000191201.7
caspase 8
chr9_-_106035308 2.21 ENSMUST00000159809.2
ENSMUST00000162562.2
ENSMUST00000036382.13
glycerate kinase
chr14_+_54491637 2.13 ENSMUST00000180359.8
ENSMUST00000199338.2
abhydrolase domain containing 4
chr19_+_27194411 2.10 ENSMUST00000164746.8
ENSMUST00000172302.8
very low density lipoprotein receptor
chr7_+_130633776 2.02 ENSMUST00000084509.7
ENSMUST00000213064.3
ENSMUST00000208311.4
deleted in malignant brain tumors 1
chr7_+_119773070 1.95 ENSMUST00000033201.7
ankyrin repeat and sterile alpha motif domain containing 4B
chr6_+_116263513 1.95 ENSMUST00000221069.2
zinc finger, AN1-type domain 4
chrX_+_67805443 1.81 ENSMUST00000069731.12
ENSMUST00000114647.8
Fmr1 neighbor
chr9_+_119978773 1.79 ENSMUST00000068698.15
ENSMUST00000215512.2
ENSMUST00000111627.3
ENSMUST00000093773.8
myelin-associated oligodendrocytic basic protein
chr5_+_102992873 1.79 ENSMUST00000070000.6
Rho GTPase activating protein 24
chr2_+_3771709 1.77 ENSMUST00000177037.2
family with sequence similarity 107, member B
chr18_-_66155651 1.77 ENSMUST00000143990.2
lectin, mannose-binding, 1
chr2_+_91095597 1.76 ENSMUST00000028691.7
ADP-ribosylation factor GTPase activating protein 2
chr9_+_108925727 1.72 ENSMUST00000130366.2
plexin B1
chr2_+_173579285 1.66 ENSMUST00000067530.6
vesicle-associated membrane protein, associated protein B and C
chr17_+_57369231 1.63 ENSMUST00000097299.10
ENSMUST00000169543.8
ENSMUST00000163763.2
crumbs family member 3
chr11_-_75828551 1.56 ENSMUST00000121287.8
rabphilin 3A-like (without C2 domains)
chr8_-_23184070 1.50 ENSMUST00000131767.2
inhibitor of kappaB kinase beta
chr8_-_5155347 1.48 ENSMUST00000023835.3
solute carrier family 10, member 2
chr7_-_26866157 1.44 ENSMUST00000080058.11
egl-9 family hypoxia-inducible factor 2
chr17_+_57369490 1.43 ENSMUST00000163628.2
crumbs family member 3
chr4_-_139695337 1.41 ENSMUST00000105031.4
kelch domain containing 7A
chr5_-_100521343 1.37 ENSMUST00000182433.8
Sec31 homolog A (S. cerevisiae)
chr17_-_35265702 1.35 ENSMUST00000097338.11
mutS homolog 5
chr1_+_74700952 1.28 ENSMUST00000129890.8
tubulin tyrosine ligase-like family, member 4
chr1_+_58834532 1.26 ENSMUST00000027189.15
caspase 8
chr16_-_92155762 1.26 ENSMUST00000166707.3
potassium voltage-gated channel, Isk-related subfamily, member 1
chr14_+_33807935 1.22 ENSMUST00000022519.15
annexin A8
chr19_-_58782874 1.17 ENSMUST00000028299.11
RIKEN cDNA 1700019N19 gene
chr19_+_5928649 1.16 ENSMUST00000136833.8
ENSMUST00000141362.2
solute carrier family 25, member 45
chr3_-_98417830 1.11 ENSMUST00000196861.2
hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 4
chr10_-_7162196 1.09 ENSMUST00000015346.12
Cnksr family member 3
chr9_+_39848797 1.08 ENSMUST00000213246.3
olfactory receptor 974
chr6_-_52217821 1.08 ENSMUST00000121043.2
homeobox A10
chr5_-_35886605 1.07 ENSMUST00000070203.14
SH3 domain and tetratricopeptide repeats 1
chr11_+_83742961 1.03 ENSMUST00000146786.8
HNF1 homeobox B
chr9_+_72866067 0.94 ENSMUST00000098567.9
ENSMUST00000034734.9
dynein axonemal assembly factor 4
chr7_+_102731092 0.88 ENSMUST00000214215.2
olfactory receptor 584
chrX_+_67805497 0.87 ENSMUST00000071848.7
Fmr1 neighbor
chr14_+_33807964 0.87 ENSMUST00000120077.2
annexin A8
chr16_+_24266829 0.87 ENSMUST00000078988.10
LIM domain containing preferred translocation partner in lipoma
chr19_-_11833365 0.84 ENSMUST00000079875.4
olfactory receptor 1418
chr17_+_20634408 0.84 ENSMUST00000233980.2
ENSMUST00000233642.2
ENSMUST00000233743.2
ENSMUST00000233318.2
ENSMUST00000233161.2
ENSMUST00000233891.2
ENSMUST00000233600.2
ENSMUST00000233863.2
vomeronasal 1 receptor 224
chr18_+_47054867 0.84 ENSMUST00000234910.2
ADP-ribosylation factor-like 14 effector protein-like
chrX_-_5381319 0.83 ENSMUST00000058404.5
myc-like oncogene, s-myc protein
chr7_-_83444026 0.83 ENSMUST00000119134.8
cilia and flagella associated protein 161
chr9_-_119038162 0.83 ENSMUST00000084797.6
solute carrier family 22 (organic cation transporter), member 13
chr2_-_164063525 0.82 ENSMUST00000018355.11
ENSMUST00000109376.9
WAP four-disulfide core domain 15B
chr7_-_109271433 0.81 ENSMUST00000207394.2
DENN domain containing 2B
chr5_-_107074110 0.81 ENSMUST00000117588.8
HFM1, ATP-dependent DNA helicase homolog
chr13_-_21637874 0.79 ENSMUST00000110485.3
zinc finger and SCAN domain containing 26
chr7_-_139982831 0.78 ENSMUST00000080153.4
ENSMUST00000216053.2
ENSMUST00000217167.2
olfactory receptor 531
chr11_+_46462363 0.73 ENSMUST00000050937.7
cDNA sequence BC053393

Network of associatons between targets according to the STRING database.

First level regulatory network of Hnf1b

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
17.9 53.8 GO:0097037 heme export(GO:0097037)
10.4 125.1 GO:0052696 flavonoid glucuronidation(GO:0052696) xenobiotic glucuronidation(GO:0052697)
10.0 10.0 GO:0050787 detoxification of mercury ion(GO:0050787)
6.1 30.4 GO:0009441 glycolate metabolic process(GO:0009441)
4.5 13.5 GO:0051659 maintenance of mitochondrion location(GO:0051659)
4.5 13.4 GO:0009812 flavonoid metabolic process(GO:0009812)
4.3 17.1 GO:0052695 cellular glucuronidation(GO:0052695)
4.0 12.0 GO:0042977 regulation of activation of JAK2 kinase activity(GO:0010534) activation of JAK2 kinase activity(GO:0042977) negative regulation of activation of JAK2 kinase activity(GO:1902569)
3.4 13.6 GO:1901373 positive regulation of intracellular lipid transport(GO:0032379) positive regulation of intracellular sterol transport(GO:0032382) positive regulation of intracellular cholesterol transport(GO:0032385) lipid hydroperoxide transport(GO:1901373)
3.2 16.2 GO:0051919 positive regulation of fibrinolysis(GO:0051919)
3.0 9.1 GO:0060392 negative regulation of SMAD protein import into nucleus(GO:0060392)
2.9 11.6 GO:0015851 nucleobase transport(GO:0015851) pyrimidine nucleobase transport(GO:0015855)
2.8 19.9 GO:0015842 aminergic neurotransmitter loading into synaptic vesicle(GO:0015842)
2.8 41.6 GO:0015747 urate transport(GO:0015747)
2.7 13.7 GO:0010760 negative regulation of macrophage chemotaxis(GO:0010760)
2.6 25.9 GO:0015712 hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
2.5 15.2 GO:0038161 prolactin signaling pathway(GO:0038161)
2.5 12.6 GO:0006548 histidine catabolic process(GO:0006548)
2.5 10.0 GO:0034971 histone H3-R17 methylation(GO:0034971) bile acid signaling pathway(GO:0038183)
2.4 46.4 GO:0042359 vitamin D metabolic process(GO:0042359)
2.4 11.8 GO:1904720 regulation of mRNA cleavage(GO:0031437) negative regulation of mRNA cleavage(GO:0031438) regulation of mRNA endonucleolytic cleavage involved in unfolded protein response(GO:1904720) negative regulation of mRNA endonucleolytic cleavage involved in unfolded protein response(GO:1904721)
2.4 16.5 GO:0000103 sulfate assimilation(GO:0000103)
2.3 7.0 GO:0033189 response to vitamin A(GO:0033189)
2.3 9.1 GO:0015886 heme transport(GO:0015886)
2.2 11.2 GO:0034371 chylomicron remodeling(GO:0034371)
2.2 13.3 GO:0051005 negative regulation of lipoprotein lipase activity(GO:0051005)
2.1 27.2 GO:0001867 complement activation, lectin pathway(GO:0001867)
2.0 18.2 GO:0034196 acylglycerol transport(GO:0034196) triglyceride transport(GO:0034197)
2.0 5.9 GO:0042362 fat-soluble vitamin biosynthetic process(GO:0042362)
1.8 12.9 GO:1901475 pyruvate transmembrane transport(GO:1901475)
1.7 6.9 GO:0009436 glyoxylate catabolic process(GO:0009436)
1.7 10.3 GO:1903243 negative regulation of cardiac muscle adaptation(GO:0010616) negative regulation of cardiac muscle hypertrophy in response to stress(GO:1903243)
1.7 5.0 GO:0001966 thigmotaxis(GO:0001966)
1.6 14.2 GO:0006528 asparagine metabolic process(GO:0006528)
1.6 9.4 GO:0043102 amino acid salvage(GO:0043102) L-methionine salvage(GO:0071267)
1.6 9.3 GO:0019532 oxalate transport(GO:0019532)
1.5 7.7 GO:1904253 positive regulation of bile acid biosynthetic process(GO:0070859) positive regulation of bile acid metabolic process(GO:1904253)
1.5 13.4 GO:0019695 choline metabolic process(GO:0019695)
1.5 7.3 GO:0015788 UDP-N-acetylglucosamine transport(GO:0015788)
1.4 9.6 GO:0009750 response to fructose(GO:0009750)
1.4 9.6 GO:0006083 acetate metabolic process(GO:0006083)
1.3 27.9 GO:0006704 glucocorticoid biosynthetic process(GO:0006704)
1.2 12.2 GO:0006729 tetrahydrobiopterin biosynthetic process(GO:0006729)
1.0 5.9 GO:0016557 peroxisome membrane biogenesis(GO:0016557)
0.9 4.7 GO:1902498 regulation of protein autoubiquitination(GO:1902498)
0.9 5.3 GO:0060745 prostate epithelial cord elongation(GO:0060523) mammary gland branching involved in pregnancy(GO:0060745)
0.9 4.4 GO:0060971 embryonic heart tube left/right pattern formation(GO:0060971)
0.7 4.3 GO:0009235 cobalamin metabolic process(GO:0009235)
0.7 4.0 GO:0021615 specification of organ position(GO:0010159) glossopharyngeal nerve morphogenesis(GO:0021615)
0.6 2.4 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.6 37.5 GO:0006805 xenobiotic metabolic process(GO:0006805)
0.6 4.0 GO:0006659 phosphatidylserine biosynthetic process(GO:0006659)
0.6 3.3 GO:0036112 medium-chain fatty-acyl-CoA metabolic process(GO:0036112)
0.5 5.8 GO:0015868 purine ribonucleotide transport(GO:0015868)
0.5 3.1 GO:1903903 regulation of establishment of T cell polarity(GO:1903903)
0.5 77.7 GO:0006958 complement activation, classical pathway(GO:0006958)
0.5 3.0 GO:0034334 adherens junction maintenance(GO:0034334)
0.5 7.7 GO:0051026 chiasma assembly(GO:0051026)
0.4 1.7 GO:1900220 semaphorin-plexin signaling pathway involved in bone trabecula morphogenesis(GO:1900220)
0.4 1.7 GO:0046725 modulation by host of viral RNA genome replication(GO:0044830) negative regulation by virus of viral protein levels in host cell(GO:0046725)
0.4 4.5 GO:0061113 pancreas morphogenesis(GO:0061113)
0.4 18.8 GO:0051180 vitamin transport(GO:0051180)
0.4 2.1 GO:0034436 glycoprotein transport(GO:0034436)
0.3 3.5 GO:0036462 TRAIL-activated apoptotic signaling pathway(GO:0036462)
0.3 4.9 GO:0032119 sequestering of zinc ion(GO:0032119) regulation of sequestering of zinc ion(GO:0061088)
0.3 4.5 GO:0046415 urate metabolic process(GO:0046415)
0.3 3.1 GO:0045198 establishment of epithelial cell apical/basal polarity(GO:0045198)
0.3 1.5 GO:1903347 negative regulation of bicellular tight junction assembly(GO:1903347)
0.3 47.3 GO:0035725 sodium ion transmembrane transport(GO:0035725)
0.3 6.7 GO:0006991 response to sterol depletion(GO:0006991) SREBP signaling pathway(GO:0032933) cellular response to sterol depletion(GO:0071501)
0.3 1.0 GO:0061228 regulation of pronephros size(GO:0035565) mesonephros morphogenesis(GO:0061206) mesonephric nephron development(GO:0061215) mesonephric nephron morphogenesis(GO:0061228) mesenchymal stem cell maintenance involved in mesonephric nephron morphogenesis(GO:0061235) regulation of mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis(GO:0061295) negative regulation of mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis(GO:0061296) mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis(GO:1901146)
0.2 6.9 GO:0070328 acylglycerol homeostasis(GO:0055090) triglyceride homeostasis(GO:0070328)
0.2 2.3 GO:0030050 vesicle transport along actin filament(GO:0030050)
0.2 2.4 GO:0018026 peptidyl-lysine monomethylation(GO:0018026)
0.2 1.8 GO:0035021 negative regulation of Rac protein signal transduction(GO:0035021)
0.2 4.5 GO:1902043 positive regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902043)
0.2 0.7 GO:0032747 positive regulation of interleukin-23 production(GO:0032747)
0.2 1.4 GO:0018401 peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401)
0.2 2.3 GO:0030277 maintenance of gastrointestinal epithelium(GO:0030277)
0.1 3.3 GO:0010225 response to UV-C(GO:0010225)
0.1 16.7 GO:0032411 positive regulation of transporter activity(GO:0032411)
0.1 2.9 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.1 4.5 GO:0015985 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.1 3.0 GO:0033194 response to hydroperoxide(GO:0033194)
0.1 3.1 GO:0015813 L-glutamate transport(GO:0015813)
0.1 0.4 GO:0090080 positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway(GO:0090080)
0.1 1.3 GO:0018095 protein polyglutamylation(GO:0018095)
0.1 5.2 GO:0010824 regulation of centrosome duplication(GO:0010824)
0.1 2.0 GO:0001833 inner cell mass cell proliferation(GO:0001833)
0.1 1.4 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.1 3.2 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.1 0.7 GO:0015838 amino-acid betaine transport(GO:0015838)
0.1 13.4 GO:0007050 cell cycle arrest(GO:0007050)
0.1 0.2 GO:0052203 modulation by symbiont of host molecular function(GO:0052055) modulation of catalytic activity in other organism involved in symbiotic interaction(GO:0052203) modulation by host of symbiont catalytic activity(GO:0052422)
0.1 0.5 GO:0009249 protein lipoylation(GO:0009249)
0.1 1.5 GO:0015721 bile acid and bile salt transport(GO:0015721)
0.1 0.8 GO:0000712 resolution of meiotic recombination intermediates(GO:0000712)
0.0 21.5 GO:0032259 methylation(GO:0032259)
0.0 1.1 GO:0060065 uterus development(GO:0060065)
0.0 1.1 GO:0035634 response to stilbenoid(GO:0035634)
0.0 6.1 GO:0051592 response to calcium ion(GO:0051592)
0.0 0.7 GO:0031115 negative regulation of microtubule polymerization(GO:0031115)
0.0 0.9 GO:0032011 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.0 0.1 GO:0072161 mesenchymal cell differentiation involved in kidney development(GO:0072161) mesenchymal cell differentiation involved in renal system development(GO:2001012)
0.0 0.6 GO:0006198 cAMP catabolic process(GO:0006198)
0.0 1.8 GO:0006888 ER to Golgi vesicle-mediated transport(GO:0006888)
0.0 3.7 GO:0035023 regulation of Rho protein signal transduction(GO:0035023)
0.0 1.7 GO:0006821 chloride transport(GO:0006821)
0.0 2.3 GO:0019233 sensory perception of pain(GO:0019233)
0.0 0.5 GO:0070232 regulation of T cell apoptotic process(GO:0070232)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
17.9 53.8 GO:0061474 phagolysosome membrane(GO:0061474)
2.7 16.2 GO:0044218 other organism cell membrane(GO:0044218) other organism membrane(GO:0044279)
1.8 26.8 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
1.7 13.7 GO:0005579 membrane attack complex(GO:0005579)
1.1 4.4 GO:0097543 ciliary inversin compartment(GO:0097543)
1.0 13.6 GO:0031315 extrinsic component of mitochondrial outer membrane(GO:0031315)
0.8 5.3 GO:0097550 transcriptional preinitiation complex(GO:0097550)
0.7 3.5 GO:0030690 Noc1p-Noc2p complex(GO:0030690)
0.6 10.0 GO:0046581 intercellular canaliculus(GO:0046581)
0.5 20.3 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.4 3.1 GO:0097441 basilar dendrite(GO:0097441)
0.3 36.8 GO:0005811 lipid particle(GO:0005811)
0.3 76.5 GO:0072562 blood microparticle(GO:0072562)
0.3 4.9 GO:0045263 proton-transporting ATP synthase complex, coupling factor F(o)(GO:0045263)
0.2 25.8 GO:0005581 collagen trimer(GO:0005581)
0.2 5.8 GO:0005922 connexon complex(GO:0005922)
0.2 8.3 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
0.2 2.0 GO:0030670 phagocytic vesicle membrane(GO:0030670)
0.2 3.1 GO:0001931 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.2 10.0 GO:0005719 nuclear euchromatin(GO:0005719)
0.2 2.1 GO:0034361 very-low-density lipoprotein particle(GO:0034361) triglyceride-rich lipoprotein particle(GO:0034385)
0.1 33.6 GO:0042579 peroxisome(GO:0005777) microbody(GO:0042579)
0.1 24.6 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)
0.1 6.1 GO:0045271 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.1 1.8 GO:0030430 host cell cytoplasm(GO:0030430) host cell cytoplasm part(GO:0033655)
0.1 1.5 GO:0008385 IkappaB kinase complex(GO:0008385)
0.1 37.2 GO:0005789 endoplasmic reticulum membrane(GO:0005789)
0.1 116.0 GO:0005783 endoplasmic reticulum(GO:0005783)
0.1 5.6 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.1 2.1 GO:0031902 late endosome membrane(GO:0031902)
0.1 4.0 GO:0031526 brush border membrane(GO:0031526)
0.1 16.7 GO:0005759 mitochondrial matrix(GO:0005759)
0.1 3.7 GO:0034707 chloride channel complex(GO:0034707)
0.1 7.3 GO:0000795 synaptonemal complex(GO:0000795)
0.0 10.3 GO:0031234 extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.0 9.1 GO:0008021 synaptic vesicle(GO:0008021)
0.0 20.7 GO:0005667 transcription factor complex(GO:0005667)
0.0 1.8 GO:0030667 secretory granule membrane(GO:0030667)
0.0 6.1 GO:0043296 apical junction complex(GO:0043296)
0.0 0.5 GO:0031143 pseudopodium(GO:0031143)
0.0 0.5 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.0 15.5 GO:0005813 centrosome(GO:0005813)
0.0 0.7 GO:0044295 axonal growth cone(GO:0044295)
0.0 1.8 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.0 0.9 GO:0097610 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 31.5 GO:0005887 integral component of plasma membrane(GO:0005887)
0.0 4.0 GO:0005769 early endosome(GO:0005769)
0.0 1.5 GO:0000502 proteasome complex(GO:0000502)
0.0 1.4 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 3.3 GO:0000151 ubiquitin ligase complex(GO:0000151)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
10.0 39.9 GO:1902271 D3 vitamins binding(GO:1902271)
7.5 22.6 GO:0008431 vitamin E binding(GO:0008431)
7.5 29.9 GO:0004062 aryl sulfotransferase activity(GO:0004062)
6.9 27.8 GO:0016899 oxidoreductase activity, acting on the CH-OH group of donors, oxygen as acceptor(GO:0016899)
6.5 25.9 GO:0050309 glucose-6-phosphatase activity(GO:0004346) sugar-terminal-phosphatase activity(GO:0050309)
5.5 87.9 GO:0005436 sodium:phosphate symporter activity(GO:0005436)
5.0 19.9 GO:0004058 aromatic-L-amino-acid decarboxylase activity(GO:0004058) L-dopa decarboxylase activity(GO:0036468)
4.2 171.6 GO:0015020 glucuronosyltransferase activity(GO:0015020)
4.1 12.2 GO:0008124 4-alpha-hydroxytetrahydrobiopterin dehydratase activity(GO:0008124)
4.0 12.0 GO:0070540 stearic acid binding(GO:0070540)
3.4 27.2 GO:0005534 galactose binding(GO:0005534)
3.4 13.6 GO:0050632 propanoyl-CoA C-acyltransferase activity(GO:0033814) propionyl-CoA C2-trimethyltridecanoyltransferase activity(GO:0050632) phosphatidylethanolamine transporter activity(GO:1904121)
3.4 13.4 GO:0046997 oxidoreductase activity, acting on the CH-NH group of donors, flavin as acceptor(GO:0046997)
3.3 10.0 GO:0038181 bile acid receptor activity(GO:0038181)
3.2 9.6 GO:0019807 aspartoacylase activity(GO:0019807)
3.0 15.2 GO:0004925 prolactin receptor activity(GO:0004925)
2.3 11.6 GO:0005345 purine nucleobase transmembrane transporter activity(GO:0005345) pyrimidine nucleobase transmembrane transporter activity(GO:0005350) nucleobase transmembrane transporter activity(GO:0015205)
2.2 11.2 GO:0035478 chylomicron binding(GO:0035478)
2.0 5.9 GO:0016900 oxidoreductase activity, acting on the CH-OH group of donors, disulfide as acceptor(GO:0016900) vitamin-K-epoxide reductase (warfarin-sensitive) activity(GO:0047057)
2.0 11.8 GO:0060698 endoribonuclease inhibitor activity(GO:0060698)
1.9 7.8 GO:0042284 sphingolipid delta-4 desaturase activity(GO:0042284)
1.8 12.9 GO:0050833 pyruvate transmembrane transporter activity(GO:0050833)
1.8 5.3 GO:0031798 type 1 metabotropic glutamate receptor binding(GO:0031798) RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding(GO:0038052)
1.7 6.9 GO:0016833 oxo-acid-lyase activity(GO:0016833)
1.7 25.3 GO:0015143 urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
1.5 9.2 GO:0060230 lipoprotein lipase activator activity(GO:0060230)
1.5 9.1 GO:0015232 heme transporter activity(GO:0015232)
1.4 27.9 GO:0016832 aldehyde-lyase activity(GO:0016832)
1.2 33.6 GO:0004033 aldo-keto reductase (NADP) activity(GO:0004033)
1.2 8.5 GO:0019770 IgG receptor activity(GO:0019770)
1.2 9.4 GO:0008172 S-methyltransferase activity(GO:0008172)
1.0 16.2 GO:1990405 protein antigen binding(GO:1990405)
1.0 3.9 GO:0003960 NADPH:quinone reductase activity(GO:0003960)
1.0 9.6 GO:0070095 fructose-6-phosphate binding(GO:0070095)
0.9 3.5 GO:0097199 cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097199)
0.7 13.5 GO:0015643 toxic substance binding(GO:0015643)
0.7 2.7 GO:0036470 tyrosine 3-monooxygenase activator activity(GO:0036470) L-dopa decarboxylase activator activity(GO:0036478)
0.7 5.9 GO:0000268 peroxisome targeting sequence binding(GO:0000268)
0.6 15.9 GO:0017081 chloride channel regulator activity(GO:0017081)
0.6 6.8 GO:0004859 phospholipase inhibitor activity(GO:0004859)
0.6 7.7 GO:0030983 mismatched DNA binding(GO:0030983)
0.6 6.5 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.6 1.7 GO:0033149 FFAT motif binding(GO:0033149)
0.5 2.1 GO:0038025 glycoprotein transporter activity(GO:0034437) reelin receptor activity(GO:0038025)
0.5 9.3 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.5 0.5 GO:0031177 phosphopantetheine binding(GO:0031177)
0.4 50.1 GO:0004869 cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.4 3.3 GO:0003996 acyl-CoA ligase activity(GO:0003996)
0.4 5.8 GO:0005243 gap junction channel activity(GO:0005243)
0.3 4.8 GO:0030274 LIM domain binding(GO:0030274)
0.3 17.5 GO:0005044 scavenger receptor activity(GO:0005044)
0.3 7.3 GO:0005351 sugar:proton symporter activity(GO:0005351)
0.2 1.5 GO:0008384 IkappaB kinase activity(GO:0008384)
0.2 26.3 GO:0008170 N-methyltransferase activity(GO:0008170)
0.2 1.5 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.2 12.6 GO:0016836 hydro-lyase activity(GO:0016836)
0.2 7.7 GO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen(GO:0016709)
0.1 4.2 GO:0097602 cullin family protein binding(GO:0097602)
0.1 0.7 GO:0032767 copper-dependent protein binding(GO:0032767)
0.1 3.1 GO:0005313 L-glutamate transmembrane transporter activity(GO:0005313)
0.1 1.7 GO:0017154 semaphorin receptor activity(GO:0017154)
0.1 4.8 GO:0042165 neurotransmitter binding(GO:0042165)
0.1 14.2 GO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides(GO:0016811)
0.1 1.4 GO:0031545 peptidyl-proline 4-dioxygenase activity(GO:0031545)
0.1 1.8 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.1 4.9 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.1 1.3 GO:0070739 protein-glutamic acid ligase activity(GO:0070739)
0.1 4.7 GO:0031435 mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.1 0.7 GO:0010853 cyclase activator activity(GO:0010853) guanylate cyclase activator activity(GO:0030250)
0.1 3.0 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.1 7.0 GO:0005548 phospholipid transporter activity(GO:0005548)
0.1 4.0 GO:0071837 HMG box domain binding(GO:0071837)
0.1 8.5 GO:0003707 steroid hormone receptor activity(GO:0003707)
0.1 7.0 GO:0042562 hormone binding(GO:0042562)
0.1 1.1 GO:0003854 3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854)
0.1 10.4 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.1 9.7 GO:0043492 ATPase activity, coupled to transmembrane movement of substances(GO:0042626) ATPase activity, coupled to movement of substances(GO:0043492)
0.0 9.0 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 2.1 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.0 3.1 GO:0035255 ionotropic glutamate receptor binding(GO:0035255)
0.0 4.3 GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups(GO:0016765)
0.0 1.3 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.0 3.4 GO:0005254 chloride channel activity(GO:0005254)
0.0 4.7 GO:0005179 hormone activity(GO:0005179)
0.0 0.2 GO:0001849 complement component C1q binding(GO:0001849)
0.0 0.5 GO:0001056 RNA polymerase III activity(GO:0001056)
0.0 5.4 GO:0044325 ion channel binding(GO:0044325)
0.0 4.0 GO:0030414 peptidase inhibitor activity(GO:0030414)
0.0 0.9 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 2.4 GO:0051087 chaperone binding(GO:0051087)
0.0 0.2 GO:1901611 phosphatidylglycerol binding(GO:1901611)
0.0 0.6 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 0.6 GO:0015347 sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.0 0.3 GO:0005537 mannose binding(GO:0005537)
0.0 1.4 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.0 0.4 GO:0017134 fibroblast growth factor binding(GO:0017134)
0.0 2.3 GO:0016853 isomerase activity(GO:0016853)
0.0 2.6 GO:0001085 RNA polymerase II transcription factor binding(GO:0001085)
0.0 3.1 GO:0005516 calmodulin binding(GO:0005516)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 20.8 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.3 27.4 PID FOXO PATHWAY FoxO family signaling
0.3 14.5 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.3 67.8 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.2 3.5 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.2 15.2 PID PTP1B PATHWAY Signaling events mediated by PTP1B
0.2 10.0 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.2 13.4 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.1 27.5 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.1 17.3 PID SMAD2 3NUCLEAR PATHWAY Regulation of nuclear SMAD2/3 signaling
0.1 6.8 PID AVB3 INTEGRIN PATHWAY Integrins in angiogenesis
0.1 6.9 PID FGF PATHWAY FGF signaling pathway
0.1 2.7 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.1 6.7 PID RHOA REG PATHWAY Regulation of RhoA activity
0.1 3.1 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 1.1 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.0 5.0 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.0 0.7 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.0 5.6 NABA SECRETED FACTORS Genes encoding secreted soluble factors
0.0 0.9 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
6.1 67.0 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
3.4 27.2 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators
1.9 27.9 REACTOME ANDROGEN BIOSYNTHESIS Genes involved in Androgen biosynthesis
1.4 37.3 REACTOME STEROID HORMONES Genes involved in Steroid hormones
1.4 15.0 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
1.2 17.2 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
1.1 21.3 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 7ALPHA HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol
1.0 19.9 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
1.0 13.4 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.8 13.9 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.7 10.3 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.6 35.5 REACTOME GLUCOSE TRANSPORT Genes involved in Glucose transport
0.6 17.4 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.5 71.2 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.5 15.2 REACTOME PROLACTIN RECEPTOR SIGNALING Genes involved in Prolactin receptor signaling
0.5 16.9 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.5 5.9 REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.4 4.5 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.4 12.0 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.4 15.9 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport
0.3 23.9 REACTOME PHASE II CONJUGATION Genes involved in Phase II conjugation
0.3 6.5 REACTOME FGFR4 LIGAND BINDING AND ACTIVATION Genes involved in FGFR4 ligand binding and activation
0.3 5.8 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.3 5.5 REACTOME REGULATION OF BETA CELL DEVELOPMENT Genes involved in Regulation of beta-cell development
0.2 47.8 REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES Genes involved in Metabolism of amino acids and derivatives
0.2 7.7 REACTOME MEIOTIC RECOMBINATION Genes involved in Meiotic Recombination
0.1 8.7 REACTOME IRON UPTAKE AND TRANSPORT Genes involved in Iron uptake and transport
0.1 7.3 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.1 1.5 REACTOME NFKB ACTIVATION THROUGH FADD RIP1 PATHWAY MEDIATED BY CASPASE 8 AND10 Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
0.1 5.3 REACTOME NUCLEAR SIGNALING BY ERBB4 Genes involved in Nuclear signaling by ERBB4
0.1 1.4 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.1 1.4 REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.1 9.8 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.1 2.5 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.0 1.7 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0 4.0 REACTOME GLYCEROPHOSPHOLIPID BIOSYNTHESIS Genes involved in Glycerophospholipid biosynthesis
0.0 0.4 REACTOME FGFR LIGAND BINDING AND ACTIVATION Genes involved in FGFR ligand binding and activation
0.0 0.5 REACTOME RNA POL III CHAIN ELONGATION Genes involved in RNA Polymerase III Chain Elongation
0.0 0.9 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.6 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 0.7 REACTOME IL RECEPTOR SHC SIGNALING Genes involved in Interleukin receptor SHC signaling
0.0 0.2 REACTOME AMYLOIDS Genes involved in Amyloids