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GSE58827: Dynamics of the Mouse Liver

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Results for Hoxa1

Z-value: 0.56

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Transcription factors associated with Hoxa1

Gene Symbol Gene ID Gene Info
Hoxa1
ENSMUSG00000029844.10 homeobox A1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Hoxa1mm39_v1_chr6_-_52135261_52135332-0.521.2e-03Click!

Activity profile of Hoxa1 motif

Sorted Z-values of Hoxa1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr8_-_118400418 3.41 ENSMUST00000173522.8
ENSMUST00000174450.2
Sdr42e1
short chain dehydrogenase/reductase family 42E, member 1
chr19_-_7943365 3.31 ENSMUST00000182102.8
ENSMUST00000075619.5
Slc22a27
solute carrier family 22, member 27
chr13_-_12355604 2.31 ENSMUST00000168193.8
ENSMUST00000064204.14
Actn2
actinin alpha 2
chr16_+_38722666 1.84 ENSMUST00000023478.8
Igsf11
immunoglobulin superfamily, member 11
chr16_-_10360893 1.72 ENSMUST00000184863.8
ENSMUST00000038281.6
Dexi
dexamethasone-induced transcript
chr2_-_103315483 1.51 ENSMUST00000028610.10
Cat
catalase
chr18_-_56695288 1.24 ENSMUST00000170309.8
Aldh7a1
aldehyde dehydrogenase family 7, member A1
chr18_-_56695333 1.18 ENSMUST00000066208.13
ENSMUST00000172734.8
Aldh7a1
aldehyde dehydrogenase family 7, member A1
chr6_-_21851827 1.18 ENSMUST00000202353.2
ENSMUST00000134635.2
ENSMUST00000123116.8
ENSMUST00000120965.8
ENSMUST00000143531.2
Tspan12
tetraspanin 12
chr18_-_56695259 1.18 ENSMUST00000171844.3
Aldh7a1
aldehyde dehydrogenase family 7, member A1
chr6_-_136852792 0.93 ENSMUST00000032342.3
Mgp
matrix Gla protein
chr10_-_125225298 0.90 ENSMUST00000210780.2
Slc16a7
solute carrier family 16 (monocarboxylic acid transporters), member 7
chr15_+_9140614 0.89 ENSMUST00000227556.3
Lmbrd2
LMBR1 domain containing 2
chr11_+_86375441 0.81 ENSMUST00000020827.7
Rnft1
ring finger protein, transmembrane 1
chr19_-_47452557 0.77 ENSMUST00000111800.4
Sh3pxd2a
SH3 and PX domains 2A
chr16_+_22926162 0.76 ENSMUST00000023599.13
ENSMUST00000168891.8
Eif4a2
eukaryotic translation initiation factor 4A2
chr2_+_152804405 0.75 ENSMUST00000099197.9
ENSMUST00000103155.10
Ttll9
tubulin tyrosine ligase-like family, member 9
chr6_-_83654789 0.75 ENSMUST00000037882.8
Cd207
CD207 antigen
chr13_+_41040657 0.64 ENSMUST00000069958.15
Gcnt2
glucosaminyl (N-acetyl) transferase 2, I-branching enzyme
chr14_+_70314652 0.64 ENSMUST00000035908.3
Egr3
early growth response 3
chr6_-_93889483 0.60 ENSMUST00000205116.3
Magi1
membrane associated guanylate kinase, WW and PDZ domain containing 1
chr17_-_25300112 0.59 ENSMUST00000024984.7
Tmem204
transmembrane protein 204
chr4_+_43669266 0.55 ENSMUST00000107864.8
Tmem8b
transmembrane protein 8B
chr19_-_3625698 0.55 ENSMUST00000172362.3
ENSMUST00000025846.16
ENSMUST00000226109.2
ENSMUST00000113997.9
Ppp6r3
protein phosphatase 6, regulatory subunit 3
chr2_-_104324035 0.53 ENSMUST00000111124.8
Hipk3
homeodomain interacting protein kinase 3
chr15_-_53209513 0.52 ENSMUST00000077273.9
Ext1
exostosin glycosyltransferase 1
chr1_+_153750081 0.50 ENSMUST00000055314.4
Teddm1b
transmembrane epididymal protein 1B
chr5_+_42225303 0.49 ENSMUST00000087332.5
Gm16223
predicted gene 16223
chr1_-_157240138 0.49 ENSMUST00000078308.13
Rasal2
RAS protein activator like 2
chr11_+_4833186 0.48 ENSMUST00000139737.2
Nipsnap1
nipsnap homolog 1
chr7_-_103320398 0.44 ENSMUST00000062144.4
Olfr624
olfactory receptor 624
chr4_-_145041710 0.42 ENSMUST00000030339.13
Tnfrsf8
tumor necrosis factor receptor superfamily, member 8
chr11_-_118460736 0.41 ENSMUST00000136551.3
Rbfox3
RNA binding protein, fox-1 homolog (C. elegans) 3
chr2_+_180829040 0.41 ENSMUST00000016488.13
ENSMUST00000108841.2
Ppdpf
pancreatic progenitor cell differentiation and proliferation factor
chr3_-_58433313 0.41 ENSMUST00000029385.9
Serp1
stress-associated endoplasmic reticulum protein 1
chr1_-_43866910 0.39 ENSMUST00000153317.6
ENSMUST00000128261.2
ENSMUST00000126008.8
ENSMUST00000139451.8
Uxs1
UDP-glucuronate decarboxylase 1
chr4_-_143026068 0.38 ENSMUST00000030317.14
Pdpn
podoplanin
chr6_+_95094721 0.37 ENSMUST00000032107.10
ENSMUST00000119582.3
Kbtbd8
kelch repeat and BTB (POZ) domain containing 8
chrX_+_109857866 0.36 ENSMUST00000078229.5
Pou3f4
POU domain, class 3, transcription factor 4
chr7_+_123061535 0.36 ENSMUST00000098056.6
Aqp8
aquaporin 8
chr10_-_33500583 0.35 ENSMUST00000161692.2
ENSMUST00000160299.2
ENSMUST00000019920.13
Clvs2
clavesin 2
chr5_-_138981842 0.34 ENSMUST00000110897.8
Pdgfa
platelet derived growth factor, alpha
chr11_-_40646090 0.33 ENSMUST00000020576.8
Ccng1
cyclin G1
chr5_+_88731386 0.32 ENSMUST00000031229.11
Rufy3
RUN and FYVE domain containing 3
chr4_-_148021159 0.31 ENSMUST00000105712.2
Plod1
procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1
chr9_+_121727421 0.31 ENSMUST00000214340.2
ENSMUST00000050327.5
Ackr2
atypical chemokine receptor 2
chr15_-_95426419 0.30 ENSMUST00000229933.2
ENSMUST00000166170.9
Nell2
NEL-like 2
chr9_+_78303059 0.30 ENSMUST00000113367.2
Ddx43
DEAD box helicase 43
chr17_+_26036893 0.30 ENSMUST00000235694.2
Fbxl16
F-box and leucine-rich repeat protein 16
chr17_-_90763300 0.29 ENSMUST00000159778.8
ENSMUST00000174337.8
ENSMUST00000172466.8
Nrxn1
neurexin I
chr15_+_89095724 0.28 ENSMUST00000227951.2
ENSMUST00000226221.2
ENSMUST00000238818.2
ENSMUST00000228284.2
Ppp6r2
protein phosphatase 6, regulatory subunit 2
chr3_+_97920819 0.28 ENSMUST00000079812.8
Notch2
notch 2
chr5_+_88731366 0.28 ENSMUST00000199312.5
Rufy3
RUN and FYVE domain containing 3
chr18_+_37108994 0.26 ENSMUST00000193984.2
Gm37388
predicted gene, 37388
chr2_+_158217558 0.26 ENSMUST00000109488.8
Snhg11
small nucleolar RNA host gene 11
chr2_-_63014622 0.25 ENSMUST00000075052.10
ENSMUST00000112454.8
Kcnh7
potassium voltage-gated channel, subfamily H (eag-related), member 7
chr1_+_74700952 0.25 ENSMUST00000129890.8
Ttll4
tubulin tyrosine ligase-like family, member 4
chr3_-_7678785 0.25 ENSMUST00000194279.6
Il7
interleukin 7
chr5_+_137059522 0.25 ENSMUST00000187382.2
Vgf
VGF nerve growth factor inducible
chr1_+_173964312 0.24 ENSMUST00000053941.4
Olfr424
olfactory receptor 424
chr4_-_106657446 0.24 ENSMUST00000148688.2
Acot11
acyl-CoA thioesterase 11
chr3_-_49711765 0.24 ENSMUST00000035931.13
Pcdh18
protocadherin 18
chr4_-_143026033 0.24 ENSMUST00000119654.2
Pdpn
podoplanin
chr15_+_100262423 0.24 ENSMUST00000175683.8
ENSMUST00000177211.2
Higd1c
HIG1 domain family, member 1C
chr5_+_137059127 0.24 ENSMUST00000041543.9
ENSMUST00000186451.2
Vgf
VGF nerve growth factor inducible
chr13_+_63387827 0.22 ENSMUST00000222929.2
Aopep
aminopeptidase O
chr2_-_69715899 0.22 ENSMUST00000060447.13
Mettl5
methyltransferase like 5
chr6_-_88423464 0.22 ENSMUST00000204459.3
ENSMUST00000203213.3
ENSMUST00000205179.3
ENSMUST00000165242.4
Eefsec
eukaryotic elongation factor, selenocysteine-tRNA-specific
chr2_+_32127309 0.22 ENSMUST00000123740.3
Pomt1
protein-O-mannosyltransferase 1
chr9_+_15150341 0.22 ENSMUST00000034413.8
Vstm5
V-set and transmembrane domain containing 5
chr6_+_15727798 0.22 ENSMUST00000128849.3
Mdfic
MyoD family inhibitor domain containing
chr14_+_66581745 0.21 ENSMUST00000152093.8
ENSMUST00000074523.13
Stmn4
stathmin-like 4
chr14_+_70314727 0.21 ENSMUST00000225200.2
Egr3
early growth response 3
chrX_-_7999009 0.21 ENSMUST00000130832.8
ENSMUST00000033506.13
ENSMUST00000115623.8
ENSMUST00000153839.2
Wdr13
WD repeat domain 13
chr15_+_74388044 0.21 ENSMUST00000042035.16
Adgrb1
adhesion G protein-coupled receptor B1
chr19_+_42040681 0.21 ENSMUST00000164518.4
4933411K16Rik
RIKEN cDNA 4933411K16 gene
chr3_-_49711706 0.21 ENSMUST00000191794.2
Pcdh18
protocadherin 18
chr7_+_73040908 0.20 ENSMUST00000128471.2
ENSMUST00000139780.3
Rgma
repulsive guidance molecule family member A
chr14_+_66581818 0.20 ENSMUST00000118426.8
ENSMUST00000121955.8
ENSMUST00000120229.8
ENSMUST00000134440.2
Stmn4
stathmin-like 4
chr10_+_81464536 0.20 ENSMUST00000129622.2
Ankrd24
ankyrin repeat domain 24
chr7_+_123061497 0.20 ENSMUST00000033023.10
Aqp8
aquaporin 8
chr8_+_11362805 0.19 ENSMUST00000033899.14
Col4a2
collagen, type IV, alpha 2
chr10_+_36383008 0.19 ENSMUST00000168572.8
Hs3st5
heparan sulfate (glucosamine) 3-O-sulfotransferase 5
chr3_-_88669551 0.19 ENSMUST00000183267.2
Syt11
synaptotagmin XI
chr13_+_63387870 0.19 ENSMUST00000159152.3
ENSMUST00000221820.2
Aopep
aminopeptidase O
chr2_-_63014514 0.18 ENSMUST00000112452.2
Kcnh7
potassium voltage-gated channel, subfamily H (eag-related), member 7
chr7_+_141048191 0.18 ENSMUST00000211071.2
Cd151
CD151 antigen
chr9_+_59496571 0.18 ENSMUST00000121266.8
ENSMUST00000118164.3
Celf6
CUGBP, Elav-like family member 6
chr4_-_148021217 0.17 ENSMUST00000019199.14
Plod1
procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1
chr15_+_98953776 0.17 ENSMUST00000229268.2
Prph
peripherin
chr13_+_31740117 0.16 ENSMUST00000042118.11
Foxq1
forkhead box Q1
chr3_+_58913234 0.15 ENSMUST00000040846.15
Med12l
mediator complex subunit 12-like
chr3_-_57202546 0.15 ENSMUST00000196506.2
Tm4sf1
transmembrane 4 superfamily member 1
chr3_-_89000591 0.15 ENSMUST00000090929.12
ENSMUST00000052539.13
Rusc1
RUN and SH3 domain containing 1
chr1_+_153541020 0.15 ENSMUST00000152114.8
ENSMUST00000111812.8
Rgs8
regulator of G-protein signaling 8
chr16_-_89284830 0.15 ENSMUST00000072280.5
Krtap8-1
keratin associated protein 8-1
chr9_-_4796217 0.14 ENSMUST00000027020.13
ENSMUST00000163309.2
Gria4
glutamate receptor, ionotropic, AMPA4 (alpha 4)
chr17_+_87224776 0.14 ENSMUST00000042172.7
Tmem247
transmembrane protein 247
chr3_-_7678796 0.14 ENSMUST00000192202.6
Il7
interleukin 7
chr7_+_119289249 0.13 ENSMUST00000047045.10
Acsm4
acyl-CoA synthetase medium-chain family member 4
chr12_-_8351954 0.13 ENSMUST00000220073.2
ENSMUST00000037313.6
Gdf7
growth differentiation factor 7
chr17_-_35023521 0.13 ENSMUST00000025223.9
Cyp21a1
cytochrome P450, family 21, subfamily a, polypeptide 1
chr14_+_56813060 0.13 ENSMUST00000161553.2
Parp4
poly (ADP-ribose) polymerase family, member 4
chr18_+_56695515 0.13 ENSMUST00000130163.8
ENSMUST00000132628.8
Phax
phosphorylated adaptor for RNA export
chr10_+_81068980 0.12 ENSMUST00000144087.2
ENSMUST00000117798.8
Zfr2
zinc finger RNA binding protein 2
chr1_+_153767478 0.12 ENSMUST00000050660.6
Teddm1a
transmembrane epididymal protein 1A
chr11_-_5848771 0.11 ENSMUST00000102921.4
Myl7
myosin, light polypeptide 7, regulatory
chr9_-_4796142 0.11 ENSMUST00000063508.15
Gria4
glutamate receptor, ionotropic, AMPA4 (alpha 4)
chr8_-_11362731 0.11 ENSMUST00000033898.10
Col4a1
collagen, type IV, alpha 1
chr9_+_58036345 0.11 ENSMUST00000085677.9
Stra6
stimulated by retinoic acid gene 6
chr15_-_78272957 0.11 ENSMUST00000169575.2
Tex33
testis expressed 33
chr7_+_139902515 0.10 ENSMUST00000078103.3
Olfr525
olfactory receptor 525
chr2_+_119803180 0.09 ENSMUST00000066058.8
Mapkbp1
mitogen-activated protein kinase binding protein 1
chr16_+_16714333 0.09 ENSMUST00000027373.12
ENSMUST00000232247.2
Ppm1f
protein phosphatase 1F (PP2C domain containing)
chr11_+_58556387 0.09 ENSMUST00000072030.4
Olfr322
olfactory receptor 322
chr10_+_81464370 0.08 ENSMUST00000123896.8
ENSMUST00000153573.2
ENSMUST00000119336.8
Ankrd24
ankyrin repeat domain 24
chr11_-_69439934 0.08 ENSMUST00000108659.2
Dnah2
dynein, axonemal, heavy chain 2
chr1_+_11063678 0.08 ENSMUST00000027056.12
Prex2
phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2
chr18_+_82929451 0.08 ENSMUST00000235902.2
Zfp516
zinc finger protein 516
chr4_+_138503046 0.07 ENSMUST00000030528.9
Pla2g2d
phospholipase A2, group IID
chr2_-_152793607 0.07 ENSMUST00000109811.4
Dusp15
dual specificity phosphatase-like 15
chr18_+_82929037 0.07 ENSMUST00000236858.2
Zfp516
zinc finger protein 516
chr9_+_58036759 0.06 ENSMUST00000133287.8
Stra6
stimulated by retinoic acid gene 6
chr2_-_152793469 0.06 ENSMUST00000037715.7
Dusp15
dual specificity phosphatase-like 15
chr9_+_58036604 0.06 ENSMUST00000034880.10
Stra6
stimulated by retinoic acid gene 6
chr6_-_52168675 0.05 ENSMUST00000101395.3
Hoxa4
homeobox A4
chr5_+_43673093 0.05 ENSMUST00000144558.3
C1qtnf7
C1q and tumor necrosis factor related protein 7
chr11_-_65050716 0.05 ENSMUST00000020855.5
ENSMUST00000108696.7
1700086D15Rik
RIKEN cDNA 1700086D15 gene
chr7_-_102507962 0.04 ENSMUST00000213481.2
ENSMUST00000209952.2
Olfr566
olfactory receptor 566
chr2_+_119803230 0.02 ENSMUST00000229024.2
Mapkbp1
mitogen-activated protein kinase binding protein 1
chr17_+_45866618 0.02 ENSMUST00000024742.9
ENSMUST00000233929.2
Nfkbie
nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, epsilon
chr6_+_40302106 0.02 ENSMUST00000031977.12
Agk
acylglycerol kinase
chr10_+_88721854 0.02 ENSMUST00000020255.8
Slc5a8
solute carrier family 5 (iodide transporter), member 8
chr7_+_144391786 0.02 ENSMUST00000155320.8
Fgf3
fibroblast growth factor 3
chr15_+_6552270 0.02 ENSMUST00000226412.2
Fyb
FYN binding protein
chr6_+_40419797 0.02 ENSMUST00000038907.9
ENSMUST00000141490.2
Wee2
WEE1 homolog 2 (S. pombe)
chr8_-_91544021 0.01 ENSMUST00000209208.2
Gm19935
predicted gene, 19935
chr10_+_67021509 0.01 ENSMUST00000173689.8
Jmjd1c
jumonji domain containing 1C
chrX_-_133062677 0.01 ENSMUST00000033611.5
Xkrx
X-linked Kx blood group related, X-linked
chr13_+_113429690 0.01 ENSMUST00000136755.10
Cspg4b
chondroitin sulfate proteoglycan 4B
chr5_-_135601887 0.01 ENSMUST00000004936.10
ENSMUST00000201401.2
Ccl24
chemokine (C-C motif) ligand 24
chrX_-_36432482 0.00 ENSMUST00000046557.6
Akap14
A kinase (PRKA) anchor protein 14
chr2_+_36342599 0.00 ENSMUST00000072854.2
Olfr340
olfactory receptor 340

Network of associatons between targets according to the STRING database.

First level regulatory network of Hoxa1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 2.3 GO:0086097 actin filament uncapping(GO:0051695) phospholipase C-activating angiotensin-activated signaling pathway(GO:0086097)
0.2 3.3 GO:0015747 urate transport(GO:0015747)
0.2 0.6 GO:1990764 regulation of myofibroblast contraction(GO:1904328) myofibroblast contraction(GO:1990764)
0.1 0.9 GO:1901475 pyruvate transmembrane transport(GO:1901475)
0.1 0.3 GO:0010512 negative regulation of phosphatidylinositol biosynthetic process(GO:0010512)
0.1 1.5 GO:0009650 UV protection(GO:0009650)
0.1 0.5 GO:0046946 hydroxylysine metabolic process(GO:0046946) hydroxylysine biosynthetic process(GO:0046947)
0.1 0.3 GO:1990705 intrahepatic bile duct development(GO:0035622) cholangiocyte proliferation(GO:1990705)
0.1 0.6 GO:0036438 maintenance of lens transparency(GO:0036438)
0.1 0.6 GO:0015722 canalicular bile acid transport(GO:0015722)
0.1 0.8 GO:0072675 osteoclast fusion(GO:0072675)
0.1 0.5 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.0 0.3 GO:0090126 protein complex assembly involved in synapse maturation(GO:0090126)
0.0 0.2 GO:1990927 negative regulation of membrane invagination(GO:1905154) calcium ion regulated lysosome exocytosis(GO:1990927)
0.0 0.8 GO:0033089 positive regulation of T cell differentiation in thymus(GO:0033089) positive regulation of thymocyte aggregation(GO:2000400)
0.0 0.1 GO:0051030 snRNA transport(GO:0051030)
0.0 0.4 GO:0014029 neural crest formation(GO:0014029)
0.0 0.2 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.0 0.2 GO:1904098 regulation of protein O-linked glycosylation(GO:1904098) positive regulation of protein O-linked glycosylation(GO:1904100)
0.0 0.5 GO:0043508 negative regulation of JUN kinase activity(GO:0043508)
0.0 1.2 GO:0010842 retina layer formation(GO:0010842)
0.0 0.2 GO:0061143 alveolar primary septum development(GO:0061143)
0.0 0.1 GO:0035992 tendon cell differentiation(GO:0035990) tendon formation(GO:0035992)
0.0 0.4 GO:0042535 positive regulation of tumor necrosis factor biosynthetic process(GO:0042535)
0.0 0.2 GO:0006451 selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)
0.0 1.1 GO:0010501 RNA secondary structure unwinding(GO:0010501)
0.0 0.3 GO:0018095 protein polyglutamylation(GO:0018095)
0.0 0.4 GO:2001054 negative regulation of mesenchymal cell apoptotic process(GO:2001054)
0.0 0.6 GO:2000114 regulation of establishment of cell polarity(GO:2000114)
0.0 0.3 GO:0046543 development of secondary female sexual characteristics(GO:0046543)
0.0 0.4 GO:0060124 positive regulation of growth hormone secretion(GO:0060124)
0.0 0.1 GO:0007256 activation of JNKK activity(GO:0007256) negative regulation of defense response to bacterium(GO:1900425)
0.0 0.4 GO:0031017 exocrine pancreas development(GO:0031017)
0.0 0.1 GO:0061304 retinal blood vessel morphogenesis(GO:0061304)
0.0 0.6 GO:0001945 lymph vessel development(GO:0001945)
0.0 0.4 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.0 0.2 GO:0061469 regulation of type B pancreatic cell proliferation(GO:0061469)
0.0 0.4 GO:0002360 T cell lineage commitment(GO:0002360)
0.0 0.1 GO:0002361 CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation(GO:0002361)
0.0 0.5 GO:0002021 response to dietary excess(GO:0002021)
0.0 0.8 GO:0043666 regulation of phosphoprotein phosphatase activity(GO:0043666)
0.0 0.3 GO:0007095 mitotic G2 DNA damage checkpoint(GO:0007095)
0.0 2.6 GO:0006694 steroid biosynthetic process(GO:0006694)
0.0 0.2 GO:0048681 negative regulation of axon regeneration(GO:0048681) negative regulation of receptor binding(GO:1900121)
0.0 0.2 GO:0038063 collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063)
0.0 0.1 GO:0044387 negative regulation of protein kinase activity by regulation of protein phosphorylation(GO:0044387)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.6 GO:0046691 intracellular canaliculus(GO:0046691)
0.1 0.6 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.0 0.3 GO:0098642 collagen type IV trimer(GO:0005587) network-forming collagen trimer(GO:0098642) collagen network(GO:0098645) basement membrane collagen trimer(GO:0098651)
0.0 2.3 GO:0005865 striated muscle thin filament(GO:0005865)
0.0 0.3 GO:0032983 kainate selective glutamate receptor complex(GO:0032983)
0.0 0.6 GO:0071437 invadopodium(GO:0071437)
0.0 0.5 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0 0.2 GO:0044299 C-fiber(GO:0044299)
0.0 0.3 GO:0036056 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.0 1.5 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.0 0.7 GO:0002102 podosome(GO:0002102)
0.0 0.2 GO:0032009 early phagosome(GO:0032009)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 3.6 GO:0008802 betaine-aldehyde dehydrogenase activity(GO:0008802)
0.5 2.3 GO:0051373 FATZ binding(GO:0051373)
0.2 3.4 GO:0003854 3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854)
0.2 0.8 GO:0004096 catalase activity(GO:0004096)
0.2 3.3 GO:1901702 urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.2 0.5 GO:0050508 glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.2 0.6 GO:0008109 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.1 0.9 GO:0050833 pyruvate transmembrane transporter activity(GO:0050833)
0.1 0.5 GO:0008475 procollagen-lysine 5-dioxygenase activity(GO:0008475)
0.1 1.2 GO:0015250 water channel activity(GO:0015250)
0.1 0.8 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.0 1.2 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.2 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.0 0.3 GO:0004971 AMPA glutamate receptor activity(GO:0004971)
0.0 0.2 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.0 0.4 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.0 0.4 GO:0048406 nerve growth factor binding(GO:0048406)
0.0 0.3 GO:0070739 protein-glutamic acid ligase activity(GO:0070739)
0.0 0.3 GO:0019957 C-C chemokine binding(GO:0019957)
0.0 0.9 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 0.4 GO:0070403 NAD+ binding(GO:0070403)
0.0 0.3 GO:0097109 neuroligin family protein binding(GO:0097109)
0.0 0.2 GO:0035368 selenocysteine insertion sequence binding(GO:0035368)
0.0 0.1 GO:0003996 acyl-CoA ligase activity(GO:0003996)
0.0 0.1 GO:0033192 calmodulin-dependent protein phosphatase activity(GO:0033192)
0.0 0.5 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.0 0.2 GO:1990459 transferrin receptor binding(GO:1990459)
0.0 1.1 GO:0003724 RNA helicase activity(GO:0003724) ATP-dependent RNA helicase activity(GO:0004004)
0.0 0.4 GO:0003680 AT DNA binding(GO:0003680)
0.0 0.5 GO:0042165 neurotransmitter binding(GO:0042165)
0.0 0.4 GO:0005242 inward rectifier potassium channel activity(GO:0005242)
0.0 0.2 GO:0030957 Tat protein binding(GO:0030957)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 0.9 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 0.8 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES Genes involved in Cross-presentation of soluble exogenous antigens (endosomes)
0.1 1.5 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.1 2.6 REACTOME UNBLOCKING OF NMDA RECEPTOR GLUTAMATE BINDING AND ACTIVATION Genes involved in Unblocking of NMDA receptor, glutamate binding and activation
0.1 0.9 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.0 0.6 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.0 0.8 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.0 0.3 REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.0 0.7 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 0.4 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.0 3.6 REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES Genes involved in Metabolism of amino acids and derivatives