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GSE58827: Dynamics of the Mouse Liver

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Results for Hoxa4

Z-value: 1.40

Motif logo

Transcription factors associated with Hoxa4

Gene Symbol Gene ID Gene Info
ENSMUSG00000000942.11 homeobox A4

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Hoxa4mm39_v1_chr6_-_52168675_52168733-0.643.0e-05Click!

Activity profile of Hoxa4 motif

Sorted Z-values of Hoxa4 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr4_-_61259997 24.49 ENSMUST00000071005.9
ENSMUST00000075206.12
major urinary protein 14
chr4_-_60222580 22.84 ENSMUST00000095058.5
ENSMUST00000163931.8
major urinary protein 8
chr4_-_61259801 22.45 ENSMUST00000125461.8
major urinary protein 14
chr4_-_60697274 14.12 ENSMUST00000117932.2
major urinary protein 12
chr7_-_19432933 11.29 ENSMUST00000174355.8
ENSMUST00000172983.8
ENSMUST00000174710.2
ENSMUST00000003066.16
ENSMUST00000174064.9
apolipoprotein E
chr5_-_87074380 8.52 ENSMUST00000031183.3
UDP glucuronosyltransferase 2 family, polypeptide B1
chr1_-_180021039 6.65 ENSMUST00000160482.8
ENSMUST00000170472.8
coenzyme Q8A
chr9_-_50466470 6.51 ENSMUST00000119103.2
beta-carotene oxygenase 2
chr1_-_180021218 5.96 ENSMUST00000159914.8
coenzyme Q8A
chr7_+_51528715 5.68 ENSMUST00000051912.13
growth arrest specific 2
chr10_+_87695117 5.59 ENSMUST00000105300.9
insulin-like growth factor 1
chr7_+_51528788 5.14 ENSMUST00000107591.9
growth arrest specific 2
chr1_+_74324089 4.64 ENSMUST00000113805.8
ENSMUST00000027370.13
ENSMUST00000087226.11
paroxysmal nonkinesiogenic dyskinesia
chr10_+_87694924 4.51 ENSMUST00000095360.11
insulin-like growth factor 1
chr16_+_37400590 4.27 ENSMUST00000159787.8
homogentisate 1, 2-dioxygenase
chr16_+_22676589 4.13 ENSMUST00000004574.14
ENSMUST00000178320.2
ENSMUST00000166487.10
DnaJ heat shock protein family (Hsp40) member B11
chr1_+_87998487 3.95 ENSMUST00000073772.5
UDP glucuronosyltransferase 1 family, polypeptide A9
chr16_+_37400500 3.85 ENSMUST00000160847.2
homogentisate 1, 2-dioxygenase
chr11_-_43727071 3.74 ENSMUST00000167574.2
adrenergic receptor, alpha 1b
chr9_-_65792306 3.72 ENSMUST00000122410.8
ENSMUST00000117083.2
thyroid hormone receptor interactor 4
chr6_-_116084810 3.58 ENSMUST00000204353.3
transmembrane and coiled coil domains 1
chr15_+_10249646 3.54 ENSMUST00000134410.8
prolactin receptor
chrM_+_5319 3.34 ENSMUST00000082402.1
mitochondrially encoded cytochrome c oxidase I
chr12_-_57592907 3.23 ENSMUST00000044380.8
forkhead box A1
chr11_-_116080361 3.14 ENSMUST00000148601.2
acyl-Coenzyme A oxidase 1, palmitoyl
chr12_+_59176543 3.04 ENSMUST00000069430.15
ENSMUST00000177370.8
MIA SH3 domain ER export factor 2
chr11_+_94219046 3.02 ENSMUST00000021227.6
ankyrin repeat domain 40
chr2_-_5680801 2.95 ENSMUST00000114987.4
calcium/calmodulin-dependent protein kinase ID
chr2_+_70305267 2.84 ENSMUST00000100043.3
trans-acting transcription factor 5
chr11_+_94218810 2.76 ENSMUST00000107818.9
ENSMUST00000051221.13
ankyrin repeat domain 40
chr10_-_126956991 2.73 ENSMUST00000080975.6
ENSMUST00000164259.9
amplified in osteosarcoma
chr5_+_73648368 2.56 ENSMUST00000113558.8
ENSMUST00000063882.12
DCN1, defective in cullin neddylation 1, domain containing 4 (S. cerevisiae)
chr5_+_42225303 2.55 ENSMUST00000087332.5
predicted gene 16223
chr12_+_59176506 2.51 ENSMUST00000175912.8
ENSMUST00000176892.8
MIA SH3 domain ER export factor 2
chr19_+_31846154 2.43 ENSMUST00000224564.2
ENSMUST00000224304.2
ENSMUST00000075838.8
ENSMUST00000224400.2
APOBEC1 complementation factor
chr6_+_43242516 2.42 ENSMUST00000031750.14
Rho guanine nucleotide exchange factor (GEF) 5
chr4_-_134099840 2.42 ENSMUST00000030643.3
exostosin-like glycosyltransferase 1
chrX_-_105647282 2.02 ENSMUST00000113480.2
cysteinyl leukotriene receptor 1
chr5_+_30972067 2.00 ENSMUST00000200692.4
microtubule-associated protein, RP/EB family, member 3
chr14_+_47069582 1.96 ENSMUST00000068532.10
cell growth regulator with ring finger domain 1
chr1_-_93406091 1.95 ENSMUST00000188165.2
high density lipoprotein (HDL) binding protein
chrM_+_10167 1.91 ENSMUST00000082414.1
mitochondrially encoded NADH dehydrogenase 4
chr1_+_133109059 1.85 ENSMUST00000187285.7
pleckstrin homology domain containing, family A member 6
chr7_+_65343156 1.81 ENSMUST00000032726.14
ENSMUST00000107495.5
ENSMUST00000143508.3
ENSMUST00000129166.3
ENSMUST00000206517.2
ENSMUST00000206837.2
ENSMUST00000206628.2
ENSMUST00000206361.2
TM2 domain containing 3
chr9_+_7445822 1.78 ENSMUST00000034497.8
matrix metallopeptidase 3
chr10_+_84591919 1.75 ENSMUST00000060397.13
regulatory factor X, 4 (influences HLA class II expression)
chr5_-_146157711 1.71 ENSMUST00000169407.9
ENSMUST00000161331.8
ENSMUST00000159074.3
ENSMUST00000067837.10
ring finger protein (C3H2C3 type) 6
chr19_+_24853039 1.70 ENSMUST00000073080.7
predicted gene 10053
chr19_-_20931566 1.67 ENSMUST00000039500.4
transmembrane channel-like gene family 1
chr1_-_93406515 1.66 ENSMUST00000170883.8
ENSMUST00000189025.7
high density lipoprotein (HDL) binding protein
chr16_-_50252703 1.65 ENSMUST00000066037.13
ENSMUST00000089399.11
ENSMUST00000089404.10
ENSMUST00000138166.8
bobby sox HMG box containing
chr1_-_14374794 1.65 ENSMUST00000190337.7
EYA transcriptional coactivator and phosphatase 1
chr1_-_14374842 1.60 ENSMUST00000188857.7
ENSMUST00000185453.7
EYA transcriptional coactivator and phosphatase 1
chr2_+_20742115 1.50 ENSMUST00000114606.8
ENSMUST00000114608.3
enhancer trap locus 4
chr10_+_53213763 1.47 ENSMUST00000219491.2
ENSMUST00000163319.9
ENSMUST00000220197.2
ENSMUST00000046221.8
ENSMUST00000218468.2
ENSMUST00000219921.2
phospholamban
chr14_-_51134930 1.41 ENSMUST00000227271.2
kelch-like 33
chr11_-_99213769 1.40 ENSMUST00000038004.3
keratin 25
chr11_-_74228504 1.39 ENSMUST00000213831.2
olfactory receptor 410
chr12_-_83609217 1.35 ENSMUST00000222448.2
zinc finger, FYVE domain containing 1
chr2_+_70393782 1.35 ENSMUST00000123330.3
glutamate decarboxylase 1
chr19_-_43879031 1.35 ENSMUST00000212048.2
dynamin binding protein
chr6_+_54017063 1.34 ENSMUST00000127323.3
chimerin 2
chr4_+_11579648 1.32 ENSMUST00000180239.2
fibrinogen silencer binding protein
chr19_+_11943265 1.32 ENSMUST00000025590.11
oxysterol binding protein
chr7_-_84339156 1.31 ENSMUST00000209117.2
ENSMUST00000207975.2
zinc finger, AN1-type domain 6
chr14_-_80008745 1.28 ENSMUST00000039568.11
ENSMUST00000195355.2
protocadherin 8
chr14_+_47069667 1.28 ENSMUST00000140114.3
ENSMUST00000133989.8
cell growth regulator with ring finger domain 1
chr2_-_57003064 1.25 ENSMUST00000112627.2
nuclear receptor subfamily 4, group A, member 2
chr10_+_63293284 1.24 ENSMUST00000105440.8
catenin (cadherin associated protein), alpha 3
chr16_-_35891739 1.24 ENSMUST00000231351.2
ENSMUST00000004057.9
family with sequence similarity 162, member A
chr14_-_51134906 1.20 ENSMUST00000170855.2
kelch-like 33
chr2_+_83786742 1.19 ENSMUST00000178325.2
predicted gene 13698
chr14_-_30213408 1.18 ENSMUST00000112250.6
calcium channel, voltage-dependent, L type, alpha 1D subunit
chr9_+_50466127 1.15 ENSMUST00000213916.2
interleukin 18
chr6_+_29468067 1.15 ENSMUST00000143101.4
ENSMUST00000149646.3
ATPase, H+ transporting, lysosomal V1 subunit F
chr2_-_77349909 1.14 ENSMUST00000111830.9
zinc finger protein 385B
chr8_-_85663976 1.13 ENSMUST00000109741.9
ENSMUST00000119820.2
microtubule associated serine/threonine kinase 1
chr16_-_22676264 1.13 ENSMUST00000232075.2
ENSMUST00000004576.8
TBCC domain containing 1
chr8_-_45747883 1.12 ENSMUST00000026907.6
kallikrein B, plasma 1
chr16_+_35891991 1.11 ENSMUST00000164916.9
coiled-coil domain containing 58
chr19_+_8817883 1.10 ENSMUST00000086058.13
Berardinelli-Seip congenital lipodystrophy 2 (seipin)
chr17_-_43978023 1.10 ENSMUST00000233442.2
solute carrier family 25, member 27
chr11_-_74228857 1.04 ENSMUST00000214490.2
olfactory receptor 410
chr18_-_79152504 1.03 ENSMUST00000025430.11
SET binding protein 1
chr13_+_38388904 1.03 ENSMUST00000091641.13
ENSMUST00000178564.2
small nuclear ribonucleoprotein 48 (U11/U12)
chr4_+_101407608 1.00 ENSMUST00000094953.11
ENSMUST00000106933.2
DnaJ heat shock protein family (Hsp40) member C6
chr10_+_127256192 1.00 ENSMUST00000171434.8
R3H domain containing 2
chr1_-_189902868 0.99 ENSMUST00000177288.4
ENSMUST00000175916.8
prospero homeobox 1
chr3_-_32546380 0.97 ENSMUST00000164954.3
potassium large conductance calcium-activated channel, subfamily M, beta member 3
chr2_+_177969456 0.96 ENSMUST00000133267.3
phosphatase and actin regulator 3
chr8_-_68427217 0.96 ENSMUST00000098696.10
ENSMUST00000038959.16
ENSMUST00000093469.11
pleckstrin and Sec7 domain containing 3
chr14_-_36820304 0.92 ENSMUST00000022337.11
cadherin-related family member 1
chr13_-_103042294 0.91 ENSMUST00000167462.8
microtubule associated serine/threonine kinase family member 4
chr5_+_115373895 0.89 ENSMUST00000081497.13
processing of precursor 5, ribonuclease P/MRP family (S. cerevisiae)
chr11_+_21522221 0.89 ENSMUST00000131135.3
ENSMUST00000020568.10
WD repeat containing planar cell polarity effector
chr17_-_43978056 0.88 ENSMUST00000024705.6
solute carrier family 25, member 27
chr6_+_77219698 0.87 ENSMUST00000161677.2
leucine rich repeat transmembrane neuronal 1
chr17_+_93506590 0.87 ENSMUST00000064775.8
adenylate cyclase activating polypeptide 1
chr2_-_112089627 0.87 ENSMUST00000043970.2
NUT midline carcinoma, family member 1
chr6_-_69521891 0.85 ENSMUST00000103356.4
immunoglobulin kappa variable 4-57-1
chr2_+_111607774 0.85 ENSMUST00000214708.2
ENSMUST00000215244.2
olfactory receptor 1302
chrX_-_104918911 0.85 ENSMUST00000200471.2
ATRX, chromatin remodeler
chr6_+_29467717 0.82 ENSMUST00000004396.13
ATPase, H+ transporting, lysosomal V1 subunit F
chr10_+_4561974 0.82 ENSMUST00000105590.8
ENSMUST00000067086.14
estrogen receptor 1 (alpha)
chr18_+_37440497 0.82 ENSMUST00000056712.4
protocadherin beta 4
chr6_+_77219627 0.81 ENSMUST00000159616.2
leucine rich repeat transmembrane neuronal 1
chr1_-_163141230 0.81 ENSMUST00000174397.3
ENSMUST00000075805.13
paired related homeobox 1
chr17_-_46044768 0.81 ENSMUST00000178179.2
RIKEN cDNA 1600014C23 gene
chr1_-_67077906 0.80 ENSMUST00000119559.8
ENSMUST00000149996.2
ENSMUST00000027149.12
ENSMUST00000113979.10
LanC (bacterial lantibiotic synthetase component C)-like 1
chr18_-_20247666 0.79 ENSMUST00000224432.2
desmocollin 1
chr2_-_119377675 0.79 ENSMUST00000133668.2
exonuclease 3'-5' domain containing 1
chr6_+_49372463 0.79 ENSMUST00000024171.14
ENSMUST00000163954.8
ENSMUST00000172459.8
serine threonine kinase 31
chr7_-_136915602 0.78 ENSMUST00000210774.2
early B cell factor 3
chr18_+_86729645 0.78 ENSMUST00000122464.8
cerebellin 2 precursor protein
chr7_-_119744509 0.78 ENSMUST00000208874.2
ENSMUST00000033207.6
zona pellucida glycoprotein 2
chr18_+_61096597 0.77 ENSMUST00000115295.9
calcium/calmodulin-dependent protein kinase II alpha
chr18_-_61147272 0.77 ENSMUST00000025520.10
solute carrier family 6 (neurotransmitter transporter, L-proline), member 7
chr13_-_103042554 0.76 ENSMUST00000171791.8
microtubule associated serine/threonine kinase family member 4
chr13_+_83672654 0.76 ENSMUST00000199019.5
myocyte enhancer factor 2C
chrX_-_94521712 0.74 ENSMUST00000033549.3
ankyrin repeat and SOCS box-containing 12
chr4_+_150322151 0.74 ENSMUST00000141931.2
enolase 1, alpha non-neuron
chr4_+_116544509 0.74 ENSMUST00000030454.6
peroxiredoxin 1
chr7_+_141276575 0.74 ENSMUST00000185406.8
mucin 2
chr5_+_76957812 0.73 ENSMUST00000120818.8
capping protein inhibiting regulator of actin
chr3_+_41519289 0.71 ENSMUST00000168086.7
jade family PHD finger 1
chr17_+_93506435 0.71 ENSMUST00000234646.2
ENSMUST00000234081.2
adenylate cyclase activating polypeptide 1
chr1_-_163141278 0.70 ENSMUST00000027878.14
paired related homeobox 1
chr12_+_38830812 0.70 ENSMUST00000160856.8
ets variant 1
chr6_+_8949669 0.70 ENSMUST00000060369.4
neurexophilin 1
chr16_-_85698679 0.68 ENSMUST00000023611.7
a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 5 (aggrecanase-2)
chr1_-_92446141 0.67 ENSMUST00000189174.2
olfactory receptor 1414
chr12_-_84408576 0.67 ENSMUST00000021659.2
ENSMUST00000065536.9
family with sequence similarity 161, member B
chr8_+_46984016 0.67 ENSMUST00000152423.2
acyl-CoA synthetase long-chain family member 1
chr14_+_32321341 0.67 ENSMUST00000187377.7
ENSMUST00000189022.8
ENSMUST00000186452.7
paired related homeobox protein-like 1
chr13_+_83672389 0.66 ENSMUST00000200394.5
myocyte enhancer factor 2C
chr5_+_137059522 0.66 ENSMUST00000187382.2
VGF nerve growth factor inducible
chr19_-_23425757 0.66 ENSMUST00000036069.8
MAM domain containing 2
chr18_+_37433852 0.66 ENSMUST00000051754.2
protocadherin beta 3
chr11_+_97732108 0.65 ENSMUST00000155954.3
ENSMUST00000164364.2
ENSMUST00000170806.2
RIKEN cDNA B230217C12 gene
chr13_+_58956077 0.65 ENSMUST00000109838.10
neurotrophic tyrosine kinase, receptor, type 2
chr9_-_37580478 0.65 ENSMUST00000011262.4
pannexin 3
chr1_+_42734051 0.64 ENSMUST00000239323.2
ENSMUST00000199521.5
ENSMUST00000176807.3
POU domain, class 3, transcription factor 3
predicted gene 20646
chr4_+_114678919 0.64 ENSMUST00000137570.2
predicted gene 12830
chr11_-_33153587 0.63 ENSMUST00000037746.8
T cell leukemia, homeobox 3
chr15_-_99717956 0.63 ENSMUST00000109024.9
LIM domain and actin binding 1
chr7_-_34755985 0.63 ENSMUST00000130491.3
CCAAT/enhancer binding protein (C/EBP), gamma
chr19_-_38212544 0.62 ENSMUST00000067167.6
FRA10AC1 homolog (human)
chr5_+_139529643 0.62 ENSMUST00000174792.2
UNC homeobox
chr7_-_121700958 0.61 ENSMUST00000139456.2
ENSMUST00000106471.9
ENSMUST00000123296.8
ENSMUST00000033157.10
NADH:ubiquinone oxidoreductase subunit AB1
chr3_-_122910662 0.61 ENSMUST00000051443.8
synaptopodin 2
chr11_+_108814007 0.59 ENSMUST00000106711.2
axin 2
chr1_-_165762469 0.59 ENSMUST00000069609.12
ENSMUST00000111427.9
ENSMUST00000111426.11
POU domain, class 2, transcription factor 1
chr8_-_68658694 0.59 ENSMUST00000212960.2
pleckstrin and Sec7 domain containing 3
chr16_+_10630779 0.58 ENSMUST00000115822.2
predicted gene 11172
chr18_+_37622518 0.57 ENSMUST00000055949.4
protocadherin beta 18
chr5_+_115573055 0.57 ENSMUST00000136586.6
musashi RNA-binding protein 1
chr5_+_137059127 0.57 ENSMUST00000041543.9
ENSMUST00000186451.2
VGF nerve growth factor inducible
chr6_-_39787813 0.57 ENSMUST00000114797.2
ENSMUST00000031978.9
mitochondrial ribosomal protein S33
chr19_-_57185808 0.56 ENSMUST00000111546.8
actin-binding LIM protein 1
chr7_+_139753130 0.56 ENSMUST00000209314.3
ENSMUST00000213953.2
ENSMUST00000214272.2
ENSMUST00000215785.2
ENSMUST00000216023.2
olfactory receptor 523
chr11_+_56902658 0.55 ENSMUST00000094179.11
glutamate receptor, ionotropic, AMPA1 (alpha 1)
chr18_-_32082624 0.54 ENSMUST00000064016.6
G protein-coupled receptor 17
chr8_+_47439948 0.54 ENSMUST00000119686.2
ectonucleotide pyrophosphatase/phosphodiesterase 6
chr2_+_79538124 0.54 ENSMUST00000090760.9
ENSMUST00000040863.11
ENSMUST00000111780.3
protein phosphatase 1, regulatory inhibitor subunit 1C
chr3_+_93349637 0.54 ENSMUST00000064257.6
trichohyalin
chr1_-_144124871 0.54 ENSMUST00000189061.7
regulator of G-protein signaling 1
chr1_+_93406809 0.52 ENSMUST00000112912.8
septin 2
chr12_+_56742413 0.52 ENSMUST00000001538.10
paired box 9
chr14_-_109151590 0.52 ENSMUST00000100322.4
SLIT and NTRK-like family, member 1
chr1_-_92446383 0.52 ENSMUST00000062353.12
olfactory receptor 1414
chr8_+_88978600 0.51 ENSMUST00000154115.2
terminal nucleotidyltransferase 4B
chr12_-_31763859 0.50 ENSMUST00000057783.6
ENSMUST00000236002.2
ENSMUST00000174480.3
ENSMUST00000176710.2
G protein-coupled receptor 22
chr5_-_105491795 0.49 ENSMUST00000171587.2
guanylate binding protein 11
chr10_-_63926044 0.49 ENSMUST00000105439.2
leucine rich repeat transmembrane neuronal 3
chrX_+_65696608 0.49 ENSMUST00000036043.5
SLIT and NTRK-like family, member 2
chr11_+_56902624 0.48 ENSMUST00000036315.16
glutamate receptor, ionotropic, AMPA1 (alpha 1)
chr19_-_57185988 0.48 ENSMUST00000099294.9
actin-binding LIM protein 1
chr1_-_144124787 0.48 ENSMUST00000185714.2
regulator of G-protein signaling 1
chr13_+_112454981 0.47 ENSMUST00000223871.2
ankyrin repeat domain 55
chr2_-_115896279 0.47 ENSMUST00000110907.8
ENSMUST00000110908.9
Meis homeobox 2
chr17_-_84495364 0.46 ENSMUST00000060366.7
zinc finger protein 36, C3H type-like 2
chr14_-_54648057 0.46 ENSMUST00000200545.2
ENSMUST00000227967.2
solute carrier family 7 (cationic amino acid transporter, y+ system), member 7
chr1_-_5140504 0.45 ENSMUST00000147158.2
ENSMUST00000118000.8
regulator of G-protein signaling 20
chr1_+_17797257 0.45 ENSMUST00000159958.8
ENSMUST00000160305.8
ENSMUST00000095075.5
cysteine-rich secretory protein LCCL domain containing 1
chr13_+_58955506 0.45 ENSMUST00000079828.7
neurotrophic tyrosine kinase, receptor, type 2
chr13_+_22656093 0.45 ENSMUST00000226330.2
ENSMUST00000226965.2
vomeronasal 1 receptor 201
chr6_-_138404076 0.44 ENSMUST00000203435.3
LIM domain only 3
chr9_+_7347369 0.43 ENSMUST00000005950.12
ENSMUST00000065079.6
matrix metallopeptidase 12
chr7_+_131568167 0.43 ENSMUST00000045840.5
G protein-coupled receptor 26
chr18_+_61096660 0.43 ENSMUST00000039904.7
calcium/calmodulin-dependent protein kinase II alpha
chr5_-_84565218 0.42 ENSMUST00000113401.4
Eph receptor A5
chr13_+_58955675 0.42 ENSMUST00000224402.2
neurotrophic tyrosine kinase, receptor, type 2
chr10_+_34265969 0.41 ENSMUST00000105511.2
collagen, type X, alpha 1
chr7_+_144391786 0.41 ENSMUST00000155320.8
fibroblast growth factor 3
chr3_+_94744844 0.41 ENSMUST00000107270.9
pogo transposable element with ZNF domain
chr12_+_38830283 0.40 ENSMUST00000162563.8
ENSMUST00000161164.8
ENSMUST00000160996.8
ets variant 1
chr16_-_76170714 0.40 ENSMUST00000231585.2
ENSMUST00000121927.8
nuclear receptor interacting protein 1
chr6_-_52190299 0.40 ENSMUST00000128102.4
predicted gene 28308
chr12_+_38830081 0.40 ENSMUST00000095767.11
ets variant 1
chr18_+_65021974 0.39 ENSMUST00000225261.3
neural precursor cell expressed, developmentally down-regulated gene 4-like

Network of associatons between targets according to the STRING database.

First level regulatory network of Hoxa4

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
3.8 11.3 GO:1903000 regulation of lipid transport across blood brain barrier(GO:1903000) positive regulation of lipid transport across blood brain barrier(GO:1903002)
2.8 8.5 GO:0018879 biphenyl metabolic process(GO:0018879)
1.5 13.3 GO:0060741 prostate gland stromal morphogenesis(GO:0060741)
1.2 3.7 GO:0001982 baroreceptor response to decreased systemic arterial blood pressure(GO:0001982)
0.9 8.1 GO:0006572 tyrosine catabolic process(GO:0006572)
0.6 2.4 GO:0010609 mRNA localization resulting in posttranscriptional regulation of gene expression(GO:0010609)
0.6 2.4 GO:0002408 myeloid dendritic cell chemotaxis(GO:0002408)
0.6 3.5 GO:0038161 prolactin signaling pathway(GO:0038161)
0.5 3.1 GO:0033540 fatty acid beta-oxidation using acyl-CoA oxidase(GO:0033540)
0.5 6.5 GO:0008300 isoprenoid catabolic process(GO:0008300)
0.5 2.0 GO:1903033 regulation of microtubule plus-end binding(GO:1903031) positive regulation of microtubule plus-end binding(GO:1903033)
0.5 11.5 GO:0006744 ubiquinone biosynthetic process(GO:0006744)
0.5 4.6 GO:0061727 methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione(GO:0019243) methylglyoxal catabolic process(GO:0051596) methylglyoxal catabolic process to lactate(GO:0061727)
0.4 1.3 GO:0051866 general adaptation syndrome(GO:0051866)
0.4 2.0 GO:0051562 negative regulation of mitochondrial calcium ion concentration(GO:0051562)
0.4 2.7 GO:0006621 protein retention in ER lumen(GO:0006621)
0.4 3.9 GO:0052697 flavonoid glucuronidation(GO:0052696) xenobiotic glucuronidation(GO:0052697)
0.3 1.0 GO:0046619 optic placode formation involved in camera-type eye formation(GO:0046619)
0.3 1.6 GO:0071651 positive regulation of chemokine (C-C motif) ligand 5 production(GO:0071651)
0.3 3.2 GO:0072513 positive regulation of secondary heart field cardioblast proliferation(GO:0072513)
0.3 2.9 GO:0060267 positive regulation of respiratory burst(GO:0060267)
0.3 1.7 GO:0021914 negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning(GO:0021914)
0.3 1.2 GO:0042231 interleukin-13 biosynthetic process(GO:0042231)
0.3 1.7 GO:0060005 vestibular reflex(GO:0060005)
0.3 1.5 GO:0099540 synaptic signaling via neuropeptide(GO:0099538) trans-synaptic signaling by neuropeptide(GO:0099540) trans-synaptic signaling by neuropeptide, modulating synaptic transmission(GO:0099551)
0.2 1.7 GO:0044314 protein K27-linked ubiquitination(GO:0044314)
0.2 1.2 GO:0086046 membrane depolarization during SA node cell action potential(GO:0086046)
0.2 1.1 GO:0051684 maintenance of Golgi location(GO:0051684)
0.2 1.1 GO:0051919 positive regulation of fibrinolysis(GO:0051919)
0.2 3.3 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.2 1.3 GO:0009449 gamma-aminobutyric acid biosynthetic process(GO:0009449)
0.2 1.2 GO:0097394 post-embryonic appendage morphogenesis(GO:0035120) post-embryonic limb morphogenesis(GO:0035127) post-embryonic forelimb morphogenesis(GO:0035128) telomeric repeat-containing RNA transcription(GO:0097393) telomeric repeat-containing RNA transcription from RNA pol II promoter(GO:0097394) regulation of telomeric RNA transcription from RNA pol II promoter(GO:1901580) negative regulation of telomeric RNA transcription from RNA pol II promoter(GO:1901581) positive regulation of telomeric RNA transcription from RNA pol II promoter(GO:1901582)
0.2 0.8 GO:0035524 proline transmembrane transport(GO:0035524)
0.2 1.8 GO:0010727 negative regulation of hydrogen peroxide metabolic process(GO:0010727)
0.2 1.5 GO:0009249 protein lipoylation(GO:0009249)
0.2 0.6 GO:0072023 ascending thin limb development(GO:0072021) thick ascending limb development(GO:0072023) metanephric ascending thin limb development(GO:0072218) metanephric thick ascending limb development(GO:0072233)
0.1 1.5 GO:0086023 adrenergic receptor signaling pathway involved in heart process(GO:0086023)
0.1 1.2 GO:0086073 bundle of His cell-Purkinje myocyte adhesion involved in cell communication(GO:0086073)
0.1 3.6 GO:0036342 post-anal tail morphogenesis(GO:0036342)
0.1 0.8 GO:0060523 prostate epithelial cord elongation(GO:0060523)
0.1 4.1 GO:0016556 mRNA modification(GO:0016556)
0.1 0.8 GO:0060468 prevention of polyspermy(GO:0060468)
0.1 0.9 GO:0090521 glomerular visceral epithelial cell migration(GO:0090521)
0.1 0.6 GO:0071699 olfactory placode formation(GO:0030910) olfactory placode development(GO:0071698) olfactory placode morphogenesis(GO:0071699)
0.1 1.4 GO:0003185 primary heart field specification(GO:0003138) sinoatrial valve development(GO:0003172) sinoatrial valve morphogenesis(GO:0003185)
0.1 1.5 GO:0048664 neuron fate determination(GO:0048664)
0.1 1.0 GO:0005513 detection of calcium ion(GO:0005513)
0.1 1.7 GO:0002091 negative regulation of receptor internalization(GO:0002091)
0.1 0.4 GO:0001543 ovarian follicle rupture(GO:0001543)
0.1 0.6 GO:2000054 regulation of mismatch repair(GO:0032423) regulation of chondrocyte development(GO:0061181) regulation of Wnt signaling pathway involved in dorsal/ventral axis specification(GO:2000053) negative regulation of Wnt signaling pathway involved in dorsal/ventral axis specification(GO:2000054)
0.1 0.3 GO:1903487 regulation of lactation(GO:1903487)
0.1 1.2 GO:0098953 receptor diffusion trapping(GO:0098953) postsynaptic neurotransmitter receptor diffusion trapping(GO:0098970) neurotransmitter receptor diffusion trapping(GO:0099628)
0.1 1.9 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.1 0.8 GO:0019695 choline metabolic process(GO:0019695)
0.1 2.6 GO:0045116 protein neddylation(GO:0045116)
0.1 0.6 GO:0035726 common myeloid progenitor cell proliferation(GO:0035726)
0.1 1.2 GO:0043084 penile erection(GO:0043084)
0.1 1.9 GO:0045109 intermediate filament organization(GO:0045109)
0.1 0.2 GO:0060060 post-embryonic retina morphogenesis in camera-type eye(GO:0060060)
0.1 0.6 GO:0043353 enucleate erythrocyte differentiation(GO:0043353)
0.1 0.2 GO:1902871 cerebral cortex GABAergic interneuron fate commitment(GO:0021893) positive regulation of neural retina development(GO:0061075) positive regulation of retina development in camera-type eye(GO:1902868) positive regulation of amacrine cell differentiation(GO:1902871)
0.1 3.7 GO:0030520 intracellular estrogen receptor signaling pathway(GO:0030520)
0.1 0.7 GO:0044539 long-chain fatty acid import(GO:0044539)
0.1 0.3 GO:0001830 trophectodermal cell fate commitment(GO:0001830)
0.1 0.3 GO:0051799 negative regulation of hair follicle development(GO:0051799)
0.1 0.5 GO:1904627 response to phorbol 13-acetate 12-myristate(GO:1904627) cellular response to phorbol 13-acetate 12-myristate(GO:1904628)
0.1 13.0 GO:0007050 cell cycle arrest(GO:0007050)
0.1 0.3 GO:0072318 clathrin coat disassembly(GO:0072318)
0.1 0.4 GO:0072093 ureteric bud invasion(GO:0072092) metanephric renal vesicle formation(GO:0072093)
0.1 0.7 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.1 1.6 GO:0043574 protein targeting to peroxisome(GO:0006625) peroxisomal transport(GO:0043574) protein localization to peroxisome(GO:0072662) establishment of protein localization to peroxisome(GO:0072663)
0.1 2.0 GO:0015988 energy coupled proton transmembrane transport, against electrochemical gradient(GO:0015988)
0.1 1.3 GO:0044126 regulation of growth of symbiont in host(GO:0044126) modulation of growth of symbiont involved in interaction with host(GO:0044144)
0.0 0.7 GO:0030277 maintenance of gastrointestinal epithelium(GO:0030277)
0.0 0.4 GO:1902739 type I interferon secretion(GO:0072641) interferon-alpha secretion(GO:0072642) regulation of interferon-alpha secretion(GO:1902739) positive regulation of interferon-alpha secretion(GO:1902741)
0.0 1.1 GO:0034389 lipid particle organization(GO:0034389)
0.0 3.4 GO:0007029 endoplasmic reticulum organization(GO:0007029)
0.0 0.7 GO:0021559 trigeminal nerve development(GO:0021559)
0.0 0.6 GO:2000298 regulation of Rho-dependent protein serine/threonine kinase activity(GO:2000298)
0.0 4.9 GO:0042632 cholesterol homeostasis(GO:0042632) sterol homeostasis(GO:0055092)
0.0 0.4 GO:0021942 radial glia guided migration of Purkinje cell(GO:0021942)
0.0 2.6 GO:0002437 inflammatory response to antigenic stimulus(GO:0002437)
0.0 1.6 GO:0032012 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.0 0.1 GO:0006500 N-terminal protein palmitoylation(GO:0006500)
0.0 0.1 GO:0021759 globus pallidus development(GO:0021759)
0.0 0.2 GO:0014732 skeletal muscle atrophy(GO:0014732)
0.0 0.3 GO:1901621 negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:1901621)
0.0 0.5 GO:1902004 positive regulation of beta-amyloid formation(GO:1902004)
0.0 0.3 GO:0045919 positive regulation of cytolysis(GO:0045919)
0.0 0.8 GO:0034587 piRNA metabolic process(GO:0034587)
0.0 0.2 GO:1904587 response to glycoprotein(GO:1904587)
0.0 0.7 GO:0071450 removal of superoxide radicals(GO:0019430) cellular response to oxygen radical(GO:0071450) cellular response to superoxide(GO:0071451)
0.0 0.5 GO:0043983 histone H4-K12 acetylation(GO:0043983)
0.0 0.2 GO:0007527 adult somatic muscle development(GO:0007527)
0.0 0.2 GO:0097475 motor neuron migration(GO:0097475)
0.0 0.3 GO:0048935 peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.0 0.6 GO:0002087 regulation of respiratory gaseous exchange by neurological system process(GO:0002087)
0.0 0.1 GO:0008588 release of cytoplasmic sequestered NF-kappaB(GO:0008588)
0.0 1.2 GO:0090200 positive regulation of release of cytochrome c from mitochondria(GO:0090200)
0.0 0.4 GO:0032793 positive regulation of CREB transcription factor activity(GO:0032793)
0.0 0.1 GO:0010841 positive regulation of circadian sleep/wake cycle, wakefulness(GO:0010841)
0.0 0.4 GO:1904861 excitatory synapse assembly(GO:1904861)
0.0 0.6 GO:0032291 central nervous system myelination(GO:0022010) axon ensheathment in central nervous system(GO:0032291) long-chain fatty acid biosynthetic process(GO:0042759)
0.0 0.2 GO:0010966 regulation of phosphate transport(GO:0010966)
0.0 0.2 GO:1903566 positive regulation of protein localization to cilium(GO:1903566)
0.0 0.3 GO:2001288 positive regulation of caveolin-mediated endocytosis(GO:2001288)
0.0 0.2 GO:0019372 lipoxygenase pathway(GO:0019372)
0.0 3.3 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 1.0 GO:0007616 long-term memory(GO:0007616)
0.0 2.5 GO:0008203 cholesterol metabolic process(GO:0008203)
0.0 0.3 GO:0000712 resolution of meiotic recombination intermediates(GO:0000712)
0.0 1.8 GO:0030032 lamellipodium assembly(GO:0030032)
0.0 0.2 GO:1902459 positive regulation of stem cell population maintenance(GO:1902459)
0.0 0.3 GO:0007379 segment specification(GO:0007379)
0.0 2.2 GO:0007416 synapse assembly(GO:0007416)
0.0 0.4 GO:0042118 endothelial cell activation(GO:0042118)
0.0 0.3 GO:0048665 neuron fate specification(GO:0048665)
0.0 0.2 GO:0006751 glutathione catabolic process(GO:0006751)
0.0 0.5 GO:1900087 positive regulation of G1/S transition of mitotic cell cycle(GO:1900087)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
2.3 11.3 GO:0034365 discoidal high-density lipoprotein particle(GO:0034365)
1.0 10.1 GO:0042567 insulin-like growth factor ternary complex(GO:0042567)
0.4 1.2 GO:0099573 glutamatergic postsynaptic density(GO:0099573)
0.3 2.7 GO:0000835 ER ubiquitin ligase complex(GO:0000835) Hrd1p ubiquitin ligase complex(GO:0000836)
0.3 2.4 GO:0045293 mRNA editing complex(GO:0045293)
0.3 4.1 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.2 1.4 GO:0097629 extrinsic component of omegasome membrane(GO:0097629)
0.2 1.0 GO:0044308 axonal spine(GO:0044308)
0.2 1.2 GO:1990707 subtelomeric heterochromatin(GO:1990421) nuclear subtelomeric heterochromatin(GO:1990707)
0.2 3.3 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.2 2.0 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.1 0.9 GO:0000172 ribonuclease MRP complex(GO:0000172)
0.1 5.1 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
0.1 0.8 GO:0097550 transcriptional preinitiation complex(GO:0097550)
0.1 0.8 GO:1990923 PET complex(GO:1990923)
0.1 3.6 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.1 1.2 GO:0071006 U2-type catalytic step 1 spliceosome(GO:0071006)
0.1 0.3 GO:0071821 FANCM-MHF complex(GO:0071821)
0.1 1.2 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.1 0.2 GO:0034680 integrin alpha10-beta1 complex(GO:0034680)
0.1 1.7 GO:0032426 stereocilium tip(GO:0032426)
0.1 0.3 GO:1990131 Iml1 complex(GO:1990130) Gtr1-Gtr2 GTPase complex(GO:1990131)
0.1 1.2 GO:0005916 fascia adherens(GO:0005916)
0.1 0.2 GO:0071148 TEAD-1-YAP complex(GO:0071148)
0.1 0.7 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.0 1.5 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.0 2.9 GO:0048786 presynaptic active zone(GO:0048786)
0.0 1.1 GO:0031616 spindle pole centrosome(GO:0031616)
0.0 3.8 GO:0031903 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.0 1.0 GO:0005689 U12-type spliceosomal complex(GO:0005689)
0.0 2.5 GO:0070469 respiratory chain(GO:0070469)
0.0 2.9 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 0.9 GO:0030057 desmosome(GO:0030057)
0.0 3.5 GO:0031594 neuromuscular junction(GO:0031594)
0.0 0.3 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.0 0.7 GO:0005782 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.0 2.1 GO:0014704 intercalated disc(GO:0014704)
0.0 0.3 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.0 0.8 GO:0044447 axoneme part(GO:0044447)
0.0 0.1 GO:1904602 serotonin-activated cation-selective channel complex(GO:1904602)
0.0 0.7 GO:0005921 gap junction(GO:0005921)
0.0 2.6 GO:0005902 microvillus(GO:0005902)
0.0 0.7 GO:0005771 multivesicular body(GO:0005771)
0.0 2.8 GO:0032993 protein-DNA complex(GO:0032993)
0.0 0.6 GO:0035371 microtubule plus-end(GO:0035371)
0.0 1.2 GO:0030667 secretory granule membrane(GO:0030667)
0.0 0.0 GO:0016461 unconventional myosin complex(GO:0016461)
0.0 4.5 GO:0045211 postsynaptic membrane(GO:0045211)
0.0 0.3 GO:0016327 apicolateral plasma membrane(GO:0016327)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
3.8 11.3 GO:0046911 metal chelating activity(GO:0046911)
0.9 3.7 GO:0004937 alpha1-adrenergic receptor activity(GO:0004937)
0.8 2.4 GO:0050508 glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.7 3.5 GO:0004925 prolactin receptor activity(GO:0004925)
0.6 4.6 GO:0004416 hydroxyacylglutathione hydrolase activity(GO:0004416)
0.4 3.1 GO:0016401 palmitoyl-CoA oxidase activity(GO:0016401)
0.4 14.8 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.4 2.0 GO:0004974 leukotriene receptor activity(GO:0004974)
0.4 1.2 GO:0086059 voltage-gated calcium channel activity involved SA node cell action potential(GO:0086059)
0.3 12.5 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.3 0.9 GO:0000171 ribonuclease MRP activity(GO:0000171)
0.3 0.8 GO:0031798 type 1 metabotropic glutamate receptor binding(GO:0031798) RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding(GO:0038052)
0.3 0.8 GO:0032190 acrosin binding(GO:0032190)
0.3 1.5 GO:0060175 brain-derived neurotrophic factor-activated receptor activity(GO:0060175)
0.2 1.5 GO:0042030 ATPase inhibitor activity(GO:0042030)
0.2 0.6 GO:0031177 phosphopantetheine binding(GO:0031177)
0.2 12.6 GO:0043531 ADP binding(GO:0043531)
0.2 1.3 GO:0004351 glutamate decarboxylase activity(GO:0004351)
0.2 1.2 GO:0015616 DNA translocase activity(GO:0015616)
0.2 1.7 GO:0022833 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.1 0.7 GO:0043758 acetate-CoA ligase (ADP-forming) activity(GO:0043758)
0.1 1.0 GO:0099583 AMPA glutamate receptor activity(GO:0004971) neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration(GO:0099583) transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315)
0.1 3.3 GO:0016676 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.1 1.2 GO:0086080 protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
0.1 4.7 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.1 1.3 GO:0015248 sterol transporter activity(GO:0015248)
0.1 3.1 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.1 2.6 GO:0097602 cullin family protein binding(GO:0097602)
0.1 4.1 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.1 0.8 GO:0008889 glycerophosphodiester phosphodiesterase activity(GO:0008889)
0.1 0.8 GO:0015193 L-proline transmembrane transporter activity(GO:0015193)
0.1 3.6 GO:0071837 HMG box domain binding(GO:0071837)
0.1 0.5 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.1 10.1 GO:0005496 steroid binding(GO:0005496)
0.1 1.9 GO:0008137 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.1 2.0 GO:0046961 proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.1 0.7 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.1 1.7 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.0 0.2 GO:0005105 type 1 fibroblast growth factor receptor binding(GO:0005105)
0.0 0.6 GO:0008301 DNA binding, bending(GO:0008301)
0.0 0.6 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.0 1.7 GO:0050681 androgen receptor binding(GO:0050681)
0.0 0.2 GO:0098639 collagen binding involved in cell-matrix adhesion(GO:0098639)
0.0 1.6 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 1.2 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.0 0.5 GO:0008379 thioredoxin peroxidase activity(GO:0008379)
0.0 4.1 GO:0051082 unfolded protein binding(GO:0051082)
0.0 0.6 GO:0070411 I-SMAD binding(GO:0070411)
0.0 1.0 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.0 0.8 GO:0043295 glutathione binding(GO:0043295) oligopeptide binding(GO:1900750)
0.0 0.3 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.0 0.5 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.0 0.2 GO:0003839 gamma-glutamylcyclotransferase activity(GO:0003839)
0.0 10.0 GO:0008017 microtubule binding(GO:0008017)
0.0 3.1 GO:0003727 single-stranded RNA binding(GO:0003727)
0.0 2.9 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.6 GO:0031005 filamin binding(GO:0031005)
0.0 0.7 GO:0022829 wide pore channel activity(GO:0022829)
0.0 0.4 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.0 0.3 GO:0050897 cobalt ion binding(GO:0050897)
0.0 3.6 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
0.0 0.4 GO:0005234 ionotropic glutamate receptor activity(GO:0004970) extracellular-glutamate-gated ion channel activity(GO:0005234)
0.0 0.8 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 0.7 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.0 0.3 GO:0019871 sodium channel inhibitor activity(GO:0019871)
0.0 2.1 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0 0.2 GO:0016500 protein-hormone receptor activity(GO:0016500)
0.0 1.1 GO:0002039 p53 binding(GO:0002039)
0.0 0.1 GO:0005004 GPI-linked ephrin receptor activity(GO:0005004)
0.0 0.6 GO:0003785 actin monomer binding(GO:0003785)
0.0 0.1 GO:0022850 serotonin-gated cation channel activity(GO:0022850)
0.0 2.2 GO:0002020 protease binding(GO:0002020)
0.0 0.3 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0 1.0 GO:0005550 pheromone binding(GO:0005550)
0.0 0.2 GO:0001134 transcription factor activity, transcription factor recruiting(GO:0001134)
0.0 1.3 GO:0004860 protein kinase inhibitor activity(GO:0004860)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 10.1 PID IGF1 PATHWAY IGF1 pathway
0.1 10.8 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.1 2.7 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.1 5.3 PID HNF3A PATHWAY FOXA1 transcription factor network
0.1 3.8 PID PTP1B PATHWAY Signaling events mediated by PTP1B
0.0 2.2 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.0 1.2 PID IL27 PATHWAY IL27-mediated signaling events
0.0 3.8 PID LYSOPHOSPHOLIPID PATHWAY LPA receptor mediated events
0.0 1.3 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.0 2.0 PID ENDOTHELIN PATHWAY Endothelins
0.0 1.2 PID PI3K PLC TRK PATHWAY Trk receptor signaling mediated by PI3K and PLC-gamma
0.0 1.5 PID SHP2 PATHWAY SHP2 signaling
0.0 1.3 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.0 1.0 ST MYOCYTE AD PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.0 0.5 ST G ALPHA I PATHWAY G alpha i Pathway
0.0 1.0 PID EPHB FWD PATHWAY EPHB forward signaling
0.0 0.7 ST B CELL ANTIGEN RECEPTOR B Cell Antigen Receptor
0.0 1.4 PID P38 ALPHA BETA DOWNSTREAM PATHWAY Signaling mediated by p38-alpha and p38-beta
0.0 3.3 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.0 0.3 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.0 1.9 PID RHOA REG PATHWAY Regulation of RhoA activity
0.0 1.2 PID CXCR4 PATHWAY CXCR4-mediated signaling events
0.0 0.3 PID FANCONI PATHWAY Fanconi anemia pathway
0.0 0.6 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.0 0.2 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.0 0.2 PID CDC42 PATHWAY CDC42 signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 11.3 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.4 3.9 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.3 10.8 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.2 2.6 REACTOME EICOSANOID LIGAND BINDING RECEPTORS Genes involved in Eicosanoid ligand-binding receptors
0.2 3.8 REACTOME ALPHA LINOLENIC ACID ALA METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.1 3.5 REACTOME PROLACTIN RECEPTOR SIGNALING Genes involved in Prolactin receptor signaling
0.1 3.7 REACTOME AMINE LIGAND BINDING RECEPTORS Genes involved in Amine ligand-binding receptors
0.1 2.9 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.1 2.2 REACTOME UNBLOCKING OF NMDA RECEPTOR GLUTAMATE BINDING AND ACTIVATION Genes involved in Unblocking of NMDA receptor, glutamate binding and activation
0.1 3.7 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.1 2.0 REACTOME INSULIN RECEPTOR RECYCLING Genes involved in Insulin receptor recycling
0.1 1.8 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.1 1.3 REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
0.0 0.2 REACTOME HORMONE LIGAND BINDING RECEPTORS Genes involved in Hormone ligand-binding receptors
0.0 1.0 REACTOME FGFR1 LIGAND BINDING AND ACTIVATION Genes involved in FGFR1 ligand binding and activation
0.0 0.7 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.0 0.6 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0 1.0 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.0 8.4 REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES Genes involved in Metabolism of amino acids and derivatives
0.0 1.3 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 1.8 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 0.2 REACTOME DSCAM INTERACTIONS Genes involved in DSCAM interactions
0.0 1.1 REACTOME NUCLEAR SIGNALING BY ERBB4 Genes involved in Nuclear signaling by ERBB4
0.0 0.6 REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 3 PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter
0.0 0.2 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.0 0.3 REACTOME LYSOSOME VESICLE BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis
0.0 2.6 REACTOME NGF SIGNALLING VIA TRKA FROM THE PLASMA MEMBRANE Genes involved in NGF signalling via TRKA from the plasma membrane
0.0 0.3 REACTOME FANCONI ANEMIA PATHWAY Genes involved in Fanconi Anemia pathway
0.0 0.2 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions