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GSE58827: Dynamics of the Mouse Liver

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Results for Hoxc13_Hoxd13

Z-value: 0.61

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Transcription factors associated with Hoxc13_Hoxd13

Gene Symbol Gene ID Gene Info
Hoxc13
ENSMUSG00000001655.7 homeobox C13
Hoxd13
ENSMUSG00000001819.5 homeobox D13

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Hoxd13mm39_v1_chr2_+_74498551_74498654-0.144.3e-01Click!

Activity profile of Hoxc13_Hoxd13 motif

Sorted Z-values of Hoxc13_Hoxd13 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr18_-_38342815 2.95 ENSMUST00000057185.13
Pcdh1
protocadherin 1
chr4_-_141553306 2.33 ENSMUST00000102481.4
Cela2a
chymotrypsin-like elastase family, member 2A
chr17_-_31363245 2.31 ENSMUST00000024826.8
Tff2
trefoil factor 2 (spasmolytic protein 1)
chr5_-_66238313 2.04 ENSMUST00000202700.4
ENSMUST00000094757.9
ENSMUST00000113724.6
Rbm47
RNA binding motif protein 47
chr10_+_87695352 1.96 ENSMUST00000121952.8
ENSMUST00000126490.8
Igf1
insulin-like growth factor 1
chr8_+_57004125 1.46 ENSMUST00000110322.9
ENSMUST00000040218.13
ENSMUST00000210863.2
Fbxo8
F-box protein 8
chr9_-_51240201 1.29 ENSMUST00000039959.11
ENSMUST00000238450.3
1810046K07Rik
RIKEN cDNA 1810046K07 gene
chr8_-_70591799 1.27 ENSMUST00000075724.9
Rfxank
regulatory factor X-associated ankyrin-containing protein
chr10_+_87695886 1.26 ENSMUST00000062862.13
Igf1
insulin-like growth factor 1
chr13_-_63712140 1.26 ENSMUST00000195756.6
Ptch1
patched 1
chr7_+_28240262 1.19 ENSMUST00000119180.4
Sycn
syncollin
chr5_+_114284585 1.19 ENSMUST00000102582.8
Acacb
acetyl-Coenzyme A carboxylase beta
chr10_+_116111441 1.19 ENSMUST00000218553.2
Ptprb
protein tyrosine phosphatase, receptor type, B
chr6_+_108190163 1.13 ENSMUST00000203615.3
Itpr1
inositol 1,4,5-trisphosphate receptor 1
chr3_+_79793237 1.08 ENSMUST00000029567.9
Gask1b
golgi associated kinase 1B
chr14_-_66361931 1.08 ENSMUST00000070515.2
Ephx2
epoxide hydrolase 2, cytoplasmic
chr17_+_35658131 1.07 ENSMUST00000071951.14
ENSMUST00000116598.10
ENSMUST00000078205.14
ENSMUST00000076256.8
H2-Q7
histocompatibility 2, Q region locus 7
chr16_+_34815177 1.07 ENSMUST00000231589.2
Mylk
myosin, light polypeptide kinase
chr7_+_67297152 1.07 ENSMUST00000032774.16
ENSMUST00000107471.8
Ttc23
tetratricopeptide repeat domain 23
chr2_-_127634387 1.00 ENSMUST00000135091.2
Mtln
mitoregulin
chr8_-_70591746 0.98 ENSMUST00000212320.2
Rfxank
regulatory factor X-associated ankyrin-containing protein
chr7_-_73187369 0.93 ENSMUST00000172704.6
Chd2
chromodomain helicase DNA binding protein 2
chr5_-_122639840 0.92 ENSMUST00000177974.8
Atp2a2
ATPase, Ca++ transporting, cardiac muscle, slow twitch 2
chr6_-_24528012 0.86 ENSMUST00000023851.9
Ndufa5
NADH:ubiquinone oxidoreductase subunit A5
chr6_+_108190050 0.83 ENSMUST00000032192.9
Itpr1
inositol 1,4,5-trisphosphate receptor 1
chr1_+_181952302 0.83 ENSMUST00000111018.2
ENSMUST00000027792.6
Srp9
signal recognition particle 9
chr10_+_116137277 0.76 ENSMUST00000092167.7
Ptprb
protein tyrosine phosphatase, receptor type, B
chr5_+_128677863 0.74 ENSMUST00000117102.4
Fzd10
frizzled class receptor 10
chr11_-_53321242 0.71 ENSMUST00000109019.8
Uqcrq
ubiquinol-cytochrome c reductase, complex III subunit VII
chr16_-_57051829 0.71 ENSMUST00000023431.8
Tbc1d23
TBC1 domain family, member 23
chr17_-_13981703 0.71 ENSMUST00000127032.8
Tcte2
t-complex-associated testis expressed 2
chr15_-_101336669 0.70 ENSMUST00000081945.5
Krt87
keratin 87
chr11_-_5492175 0.69 ENSMUST00000020776.5
Ccdc117
coiled-coil domain containing 117
chr5_+_90708962 0.62 ENSMUST00000094615.8
ENSMUST00000200765.2
Albfm1
albumin superfamily member 1
chr3_+_81904229 0.62 ENSMUST00000029641.10
Asic5
acid-sensing (proton-gated) ion channel family member 5
chr10_-_120815232 0.62 ENSMUST00000119944.8
ENSMUST00000119093.2
Lemd3
LEM domain containing 3
chr11_-_99907030 0.61 ENSMUST00000018399.3
Krt33a
keratin 33A
chr11_+_96085118 0.60 ENSMUST00000062709.4
Hoxb13
homeobox B13
chr16_-_57051727 0.59 ENSMUST00000226586.2
Tbc1d23
TBC1 domain family, member 23
chr19_+_18609343 0.59 ENSMUST00000159572.9
Nmrk1
nicotinamide riboside kinase 1
chr11_+_96177449 0.54 ENSMUST00000049352.8
Hoxb7
homeobox B7
chr11_-_99920694 0.54 ENSMUST00000073890.4
Krt33b
keratin 33B
chr13_-_17869314 0.54 ENSMUST00000221598.2
ENSMUST00000068545.6
ENSMUST00000220514.2
Sugct
succinyl-CoA glutarate-CoA transferase
chr18_+_36431732 0.53 ENSMUST00000210490.3
Igip
IgA inducing protein
chr6_-_52195663 0.50 ENSMUST00000134367.4
Hoxa7
homeobox A7
chr4_+_54945038 0.47 ENSMUST00000133895.8
Zfp462
zinc finger protein 462
chr10_+_28544556 0.46 ENSMUST00000161345.2
Themis
thymocyte selection associated
chr16_+_41353360 0.43 ENSMUST00000099761.10
Lsamp
limbic system-associated membrane protein
chr1_+_60948149 0.41 ENSMUST00000027164.9
Ctla4
cytotoxic T-lymphocyte-associated protein 4
chr13_-_51723473 0.40 ENSMUST00000239056.2
ENSMUST00000223543.3
Shc3
src homology 2 domain-containing transforming protein C3
chr1_+_107289659 0.40 ENSMUST00000027566.3
Serpinb11
serine (or cysteine) peptidase inhibitor, clade B (ovalbumin), member 11
chr12_+_11506053 0.40 ENSMUST00000124065.2
Rad51ap2
RAD51 associated protein 2
chr8_+_105991280 0.39 ENSMUST00000036221.12
Fbxl8
F-box and leucine-rich repeat protein 8
chr5_+_106024398 0.38 ENSMUST00000150440.8
ENSMUST00000031227.11
Zfp326
zinc finger protein 326
chr2_+_74528071 0.38 ENSMUST00000059272.10
Hoxd9
homeobox D9
chr1_-_138775317 0.37 ENSMUST00000093486.10
ENSMUST00000046870.13
Lhx9
LIM homeobox protein 9
chr2_-_111815654 0.36 ENSMUST00000214537.2
Olfr1309
olfactory receptor 1309
chr6_+_48425034 0.35 ENSMUST00000212740.2
ENSMUST00000169350.9
ENSMUST00000043676.12
Sspo
SCO-spondin
chr11_-_99979052 0.34 ENSMUST00000107419.2
Krt32
keratin 32
chr12_+_75355082 0.34 ENSMUST00000118602.8
ENSMUST00000118966.8
ENSMUST00000055390.6
Rhoj
ras homolog family member J
chr8_-_25528972 0.32 ENSMUST00000084031.6
Htra4
HtrA serine peptidase 4
chr17_+_8502682 0.32 ENSMUST00000124023.8
Mpc1
mitochondrial pyruvate carrier 1
chr15_-_66158445 0.32 ENSMUST00000070256.9
Kcnq3
potassium voltage-gated channel, subfamily Q, member 3
chr10_-_128532126 0.29 ENSMUST00000000727.4
Rab5b
RAB5B, member RAS oncogene family
chr5_+_135093056 0.29 ENSMUST00000071263.7
Dnajc30
DnaJ heat shock protein family (Hsp40) member C30
chr2_-_34261121 0.29 ENSMUST00000127353.3
ENSMUST00000141653.3
Pbx3
pre B cell leukemia homeobox 3
chr5_+_17779273 0.28 ENSMUST00000030568.14
Sema3c
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
chr13_-_63712349 0.26 ENSMUST00000192155.6
Ptch1
patched 1
chr10_+_28544356 0.26 ENSMUST00000060409.13
ENSMUST00000056097.11
ENSMUST00000105516.9
Themis
thymocyte selection associated
chr5_+_150119860 0.25 ENSMUST00000202600.4
Fry
FRY microtubule binding protein
chr6_+_24528143 0.25 ENSMUST00000031696.10
Asb15
ankyrin repeat and SOCS box-containing 15
chr8_+_113296675 0.24 ENSMUST00000034225.7
ENSMUST00000118171.8
Cntnap4
contactin associated protein-like 4
chr16_-_89305201 0.24 ENSMUST00000056118.4
Krtap7-1
keratin associated protein 7-1
chr11_-_99996452 0.23 ENSMUST00000107416.3
Krt36
keratin 36
chr17_+_8502594 0.23 ENSMUST00000155364.8
ENSMUST00000046754.15
Mpc1
mitochondrial pyruvate carrier 1
chr17_-_52133594 0.23 ENSMUST00000129667.8
ENSMUST00000169480.8
ENSMUST00000148559.2
Satb1
special AT-rich sequence binding protein 1
chr11_-_99412084 0.23 ENSMUST00000076948.2
Krt39
keratin 39
chr1_-_39844467 0.22 ENSMUST00000171319.4
Gm3646
predicted gene 3646
chr9_-_110775143 0.22 ENSMUST00000199782.2
ENSMUST00000035075.13
Tdgf1
teratocarcinoma-derived growth factor 1
chr16_+_23044763 0.22 ENSMUST00000178797.8
St6gal1
beta galactoside alpha 2,6 sialyltransferase 1
chr15_-_101482320 0.21 ENSMUST00000042957.6
Krt75
keratin 75
chr6_-_52194414 0.21 ENSMUST00000140316.2
Hoxa7
homeobox A7
chr1_+_53352780 0.21 ENSMUST00000027265.10
ENSMUST00000114484.8
Osgepl1
O-sialoglycoprotein endopeptidase-like 1
chr3_-_88366159 0.20 ENSMUST00000147200.8
ENSMUST00000169222.8
Sema4a
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
chr7_-_28329924 0.20 ENSMUST00000159095.2
ENSMUST00000159418.8
ENSMUST00000159560.3
Acp7
acid phosphatase 7, tartrate resistant
chr7_-_30312246 0.20 ENSMUST00000006476.6
Upk1a
uroplakin 1A
chr4_+_21879660 0.19 ENSMUST00000029909.3
Coq3
coenzyme Q3 methyltransferase
chr5_+_48140480 0.19 ENSMUST00000173107.8
ENSMUST00000174313.8
ENSMUST00000174421.8
ENSMUST00000170109.9
Slit2
slit guidance ligand 2
chr2_-_45001141 0.18 ENSMUST00000201969.4
ENSMUST00000201623.4
Zeb2
zinc finger E-box binding homeobox 2
chr11_-_99412162 0.18 ENSMUST00000107445.8
Krt39
keratin 39
chr8_-_37200051 0.18 ENSMUST00000098826.10
Dlc1
deleted in liver cancer 1
chr15_+_23036535 0.17 ENSMUST00000164787.8
Cdh18
cadherin 18
chr14_+_65903840 0.17 ENSMUST00000022610.15
Scara5
scavenger receptor class A, member 5
chr10_-_33920300 0.16 ENSMUST00000048052.7
Calhm4
calcium homeostasis modulator family member 4
chr14_+_58308004 0.16 ENSMUST00000165526.9
Fgf9
fibroblast growth factor 9
chr7_-_28330322 0.16 ENSMUST00000040112.5
ENSMUST00000239470.2
Acp7
acid phosphatase 7, tartrate resistant
chr2_-_17465410 0.15 ENSMUST00000145492.2
Nebl
nebulette
chr5_-_106606032 0.15 ENSMUST00000086795.8
Barhl2
BarH like homeobox 2
chr11_+_105885461 0.15 ENSMUST00000190995.2
Ace3
angiotensin I converting enzyme (peptidyl-dipeptidase A) 3
chr11_-_88608958 0.14 ENSMUST00000107908.2
Msi2
musashi RNA-binding protein 2
chr15_-_101441254 0.14 ENSMUST00000023720.8
Krt84
keratin 84
chr7_-_30750828 0.13 ENSMUST00000206341.2
Fxyd7
FXYD domain-containing ion transport regulator 7
chr7_-_102408573 0.13 ENSMUST00000210453.3
ENSMUST00000232246.3
ENSMUST00000239110.2
ENSMUST00000060187.15
ENSMUST00000168007.3
Olfr560
Olfr78
olfactory receptor 560
olfactory receptor 78
chr12_-_34578842 0.13 ENSMUST00000110819.4
Hdac9
histone deacetylase 9
chr18_-_46413886 0.12 ENSMUST00000236999.2
Pggt1b
protein geranylgeranyltransferase type I, beta subunit
chr11_-_99941369 0.12 ENSMUST00000007318.2
Krt31
keratin 31
chr3_-_49711706 0.12 ENSMUST00000191794.2
Pcdh18
protocadherin 18
chr4_+_134042423 0.12 ENSMUST00000105875.8
ENSMUST00000030638.7
Trim63
tripartite motif-containing 63
chr8_-_15096046 0.12 ENSMUST00000050493.4
ENSMUST00000123331.2
BB014433
expressed sequence BB014433
chr1_+_60948307 0.12 ENSMUST00000097720.4
Ctla4
cytotoxic T-lymphocyte-associated protein 4
chr3_+_126391046 0.12 ENSMUST00000106401.8
Camk2d
calcium/calmodulin-dependent protein kinase II, delta
chr9_-_96601574 0.11 ENSMUST00000128269.8
Zbtb38
zinc finger and BTB domain containing 38
chr3_-_75359125 0.11 ENSMUST00000204341.3
Wdr49
WD repeat domain 49
chr11_-_23845207 0.11 ENSMUST00000102863.3
ENSMUST00000020513.10
Papolg
poly(A) polymerase gamma
chr16_+_39804711 0.11 ENSMUST00000187695.7
Lsamp
limbic system-associated membrane protein
chr9_-_50571080 0.10 ENSMUST00000034567.4
Dlat
dihydrolipoamide S-acetyltransferase (E2 component of pyruvate dehydrogenase complex)
chr18_+_69478893 0.10 ENSMUST00000202354.4
Tcf4
transcription factor 4
chr14_-_118289557 0.10 ENSMUST00000022725.4
Dct
dopachrome tautomerase
chr10_-_107321938 0.09 ENSMUST00000000445.2
Myf5
myogenic factor 5
chrX_+_111150171 0.09 ENSMUST00000164272.3
ENSMUST00000132037.2
4933403O08Rik
RIKEN cDNA 4933403O08 gene
chr11_-_99987051 0.09 ENSMUST00000103127.4
Krt35
keratin 35
chr5_+_92957231 0.09 ENSMUST00000113054.9
Shroom3
shroom family member 3
chr2_+_20727274 0.09 ENSMUST00000114607.8
Etl4
enhancer trap locus 4
chr7_-_30750856 0.09 ENSMUST00000073892.6
Fxyd7
FXYD domain-containing ion transport regulator 7
chr11_-_102298748 0.09 ENSMUST00000124755.2
Slc25a39
solute carrier family 25, member 39
chr17_-_57307018 0.09 ENSMUST00000002740.3
Pspn
persephin
chr9_+_110948492 0.08 ENSMUST00000217341.3
Lrrfip2
leucine rich repeat (in FLII) interacting protein 2
chr7_-_133281790 0.08 ENSMUST00000033278.8
ENSMUST00000122136.2
Mmp21
matrix metallopeptidase 21
chr5_-_62923463 0.08 ENSMUST00000076623.8
ENSMUST00000159470.3
Arap2
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
chrX_-_135769285 0.07 ENSMUST00000058814.7
Rab9b
RAB9B, member RAS oncogene family
chr11_-_102298281 0.07 ENSMUST00000107098.8
ENSMUST00000018821.9
Slc25a39
solute carrier family 25, member 39
chr8_-_43981143 0.07 ENSMUST00000080135.5
Adam26b
a disintegrin and metallopeptidase domain 26B
chr3_+_102642516 0.06 ENSMUST00000119902.6
Tspan2
tetraspanin 2
chr8_+_34143266 0.06 ENSMUST00000033992.9
Gsr
glutathione reductase
chr14_+_77394173 0.06 ENSMUST00000022589.9
Enox1
ecto-NOX disulfide-thiol exchanger 1
chr17_+_37274714 0.06 ENSMUST00000209623.2
Polr1has
RNA polymerase I subunit H, antisense
chr10_-_28862289 0.06 ENSMUST00000152363.8
ENSMUST00000015663.7
2310057J18Rik
RIKEN cDNA 2310057J18 gene
chr5_-_135092904 0.05 ENSMUST00000111205.8
ENSMUST00000141309.2
Bud23
BUD23, rRNA methyltransferase and ribosome maturation factor
chr10_-_78688000 0.05 ENSMUST00000205100.3
Olfr1356
olfactory receptor 1356
chr3_+_126390951 0.05 ENSMUST00000171289.8
Camk2d
calcium/calmodulin-dependent protein kinase II, delta
chr1_-_171854818 0.04 ENSMUST00000138714.2
ENSMUST00000027837.13
ENSMUST00000111264.8
Vangl2
VANGL planar cell polarity 2
chr2_-_44912927 0.04 ENSMUST00000202432.4
Zeb2
zinc finger E-box binding homeobox 2
chr13_-_21586858 0.03 ENSMUST00000117721.8
ENSMUST00000070785.16
ENSMUST00000116433.2
ENSMUST00000223831.2
ENSMUST00000116434.11
ENSMUST00000224820.2
Zkscan3
zinc finger with KRAB and SCAN domains 3
chr9_+_38119661 0.03 ENSMUST00000211975.3
Olfr893
olfactory receptor 893
chr14_+_65903878 0.03 ENSMUST00000069226.7
Scara5
scavenger receptor class A, member 5
chr6_-_112924205 0.02 ENSMUST00000088373.11
Srgap3
SLIT-ROBO Rho GTPase activating protein 3
chr12_+_113038376 0.02 ENSMUST00000109729.3
Tex22
testis expressed gene 22
chr18_+_37488174 0.01 ENSMUST00000192867.2
ENSMUST00000051163.3
Pcdhb8
protocadherin beta 8
chr5_+_149942140 0.01 ENSMUST00000065745.10
ENSMUST00000110496.5
ENSMUST00000201612.2
Rxfp2
relaxin/insulin-like family peptide receptor 2
chr13_-_40887444 0.00 ENSMUST00000224665.2
Tfap2a
transcription factor AP-2, alpha

Network of associatons between targets according to the STRING database.

First level regulatory network of Hoxc13_Hoxd13

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 3.2 GO:1904075 regulation of trophectodermal cell proliferation(GO:1904073) positive regulation of trophectodermal cell proliferation(GO:1904075)
0.4 1.2 GO:0046949 fatty-acyl-CoA biosynthetic process(GO:0046949) malonyl-CoA metabolic process(GO:2001293)
0.4 1.1 GO:1900673 olefin metabolic process(GO:1900673)
0.3 2.3 GO:0060455 negative regulation of gastric acid secretion(GO:0060455)
0.3 0.9 GO:1903233 regulation of calcium ion-dependent exocytosis of neurotransmitter(GO:1903233)
0.3 1.5 GO:0010157 response to chlorate(GO:0010157)
0.2 1.1 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)
0.2 2.0 GO:0050882 voluntary musculoskeletal movement(GO:0050882)
0.2 0.5 GO:1902361 mitochondrial pyruvate transport(GO:0006850) mitochondrial pyruvate transmembrane transport(GO:1902361)
0.2 2.0 GO:0016554 cytidine to uridine editing(GO:0016554)
0.2 0.6 GO:0060743 epithelial cell maturation involved in prostate gland development(GO:0060743)
0.1 0.8 GO:0045900 SRP-dependent cotranslational protein targeting to membrane, translocation(GO:0006616) negative regulation of translational elongation(GO:0045900)
0.1 0.7 GO:0021539 subthalamus development(GO:0021539)
0.1 0.3 GO:0003350 pulmonary myocardium development(GO:0003350)
0.1 0.5 GO:0045590 negative regulation of regulatory T cell differentiation(GO:0045590)
0.1 0.7 GO:0038031 non-canonical Wnt signaling pathway via JNK cascade(GO:0038031)
0.1 0.2 GO:2000821 regulation of grooming behavior(GO:2000821)
0.1 3.0 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.1 0.6 GO:0070197 meiotic telomere tethering at nuclear periphery(GO:0044821) meiotic attachment of telomere to nuclear envelope(GO:0070197) chromosome attachment to the nuclear envelope(GO:0097240)
0.1 2.0 GO:0061436 establishment of skin barrier(GO:0061436)
0.1 0.3 GO:1904428 negative regulation of tubulin deacetylation(GO:1904428)
0.1 0.2 GO:1902623 corticospinal neuron axon guidance(GO:0021966) negative regulation of neutrophil migration(GO:1902623)
0.1 0.4 GO:0035262 gonad morphogenesis(GO:0035262)
0.1 0.6 GO:0045617 negative regulation of keratinocyte differentiation(GO:0045617)
0.1 0.2 GO:0002949 tRNA threonylcarbamoyladenosine modification(GO:0002949)
0.0 0.1 GO:1900135 positive regulation of renin secretion into blood stream(GO:1900135)
0.0 0.2 GO:1990743 protein sialylation(GO:1990743)
0.0 1.5 GO:0032011 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.0 0.1 GO:0014878 response to electrical stimulus involved in regulation of muscle adaptation(GO:0014878)
0.0 0.3 GO:0048227 plasma membrane to endosome transport(GO:0048227)
0.0 0.2 GO:0035022 positive regulation of Rac protein signal transduction(GO:0035022)
0.0 0.1 GO:0006583 melanin biosynthetic process from tyrosine(GO:0006583)
0.0 0.8 GO:0060218 hematopoietic stem cell differentiation(GO:0060218)
0.0 0.2 GO:1902748 positive regulation of lens fiber cell differentiation(GO:1902748)
0.0 0.7 GO:0043383 negative T cell selection(GO:0043383)
0.0 0.3 GO:0061299 retina vasculature morphogenesis in camera-type eye(GO:0061299)
0.0 1.1 GO:0002474 antigen processing and presentation of peptide antigen via MHC class I(GO:0002474)
0.0 0.1 GO:0061732 mitochondrial acetyl-CoA biosynthetic process from pyruvate(GO:0061732)
0.0 0.5 GO:0090190 positive regulation of branching involved in ureteric bud morphogenesis(GO:0090190)
0.0 0.6 GO:0019363 pyridine nucleotide biosynthetic process(GO:0019363)
0.0 0.0 GO:0061341 non-canonical Wnt signaling pathway involved in heart development(GO:0061341) planar cell polarity pathway involved in heart morphogenesis(GO:0061346)
0.0 0.4 GO:0048935 peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.0 0.5 GO:0035641 locomotory exploration behavior(GO:0035641)
0.0 0.1 GO:0070476 rRNA (guanine-N7)-methylation(GO:0070476)
0.0 0.9 GO:0010257 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.0 0.3 GO:0002087 regulation of respiratory gaseous exchange by neurological system process(GO:0002087)
0.0 0.1 GO:0035660 MyD88-dependent toll-like receptor 4 signaling pathway(GO:0035660)
0.0 0.1 GO:0051771 negative regulation of nitric-oxide synthase biosynthetic process(GO:0051771)
0.0 0.4 GO:0045616 regulation of keratinocyte differentiation(GO:0045616)
0.0 0.1 GO:0048743 positive regulation of skeletal muscle fiber development(GO:0048743)
0.0 0.1 GO:0048742 regulation of skeletal muscle fiber development(GO:0048742)
0.0 0.2 GO:0035729 cellular response to hepatocyte growth factor stimulus(GO:0035729)
0.0 0.3 GO:0060081 membrane hyperpolarization(GO:0060081)
0.0 0.2 GO:0043374 CD8-positive, alpha-beta T cell differentiation(GO:0043374)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 2.0 GO:0031088 platelet dense granule membrane(GO:0031088)
0.3 3.2 GO:0042567 insulin-like growth factor ternary complex(GO:0042567)
0.3 0.9 GO:0014801 longitudinal sarcoplasmic reticulum(GO:0014801)
0.1 0.8 GO:0005785 signal recognition particle receptor complex(GO:0005785)
0.1 1.5 GO:0044294 dendritic growth cone(GO:0044294)
0.1 1.1 GO:0042612 MHC class I protein complex(GO:0042612)
0.1 0.7 GO:0005750 mitochondrial respiratory chain complex III(GO:0005750)
0.0 0.1 GO:0005967 mitochondrial pyruvate dehydrogenase complex(GO:0005967)
0.0 2.2 GO:0045171 intercellular bridge(GO:0045171)
0.0 0.6 GO:0005639 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229)
0.0 0.8 GO:0045095 keratin filament(GO:0045095)
0.0 2.3 GO:0005882 intermediate filament(GO:0005882)
0.0 0.2 GO:0000408 EKC/KEOPS complex(GO:0000408)
0.0 1.1 GO:0097610 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 0.9 GO:0030964 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 0.2 GO:0000138 Golgi trans cisterna(GO:0000138)
0.0 0.5 GO:0031305 integral component of mitochondrial inner membrane(GO:0031305)
0.0 0.0 GO:0060187 cell pole(GO:0060187)
0.0 0.5 GO:0045334 clathrin-coated endocytic vesicle(GO:0045334)
0.0 0.7 GO:0008180 COP9 signalosome(GO:0008180)
0.0 1.2 GO:0030667 secretory granule membrane(GO:0030667)
0.0 0.5 GO:0043194 axon initial segment(GO:0043194)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 2.0 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.2 1.2 GO:0003989 acetyl-CoA carboxylase activity(GO:0003989)
0.2 1.5 GO:0008158 smoothened binding(GO:0005119) hedgehog receptor activity(GO:0008158)
0.2 1.1 GO:0004301 epoxide hydrolase activity(GO:0004301)
0.2 0.6 GO:0050262 ribosylnicotinamide kinase activity(GO:0050262) ribosylnicotinate kinase activity(GO:0061769)
0.2 2.3 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.1 0.8 GO:0005047 signal recognition particle binding(GO:0005047)
0.1 1.1 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.1 0.7 GO:0008121 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.1 0.5 GO:0050833 pyruvate transmembrane transporter activity(GO:0050833)
0.1 3.2 GO:0043539 insulin-like growth factor receptor binding(GO:0005159) protein serine/threonine kinase activator activity(GO:0043539)
0.1 0.2 GO:0061711 N(6)-L-threonylcarbamoyladenine synthase(GO:0061711)
0.1 0.3 GO:0030280 structural constituent of epidermis(GO:0030280)
0.1 0.5 GO:0008410 CoA-transferase activity(GO:0008410)
0.1 1.1 GO:0030881 beta-2-microglobulin binding(GO:0030881)
0.1 0.6 GO:0015252 hydrogen ion channel activity(GO:0015252)
0.1 0.2 GO:0038100 nodal binding(GO:0038100)
0.0 0.2 GO:0008169 C-methyltransferase activity(GO:0008169)
0.0 0.9 GO:0044548 S100 protein binding(GO:0044548)
0.0 0.2 GO:0070287 ferritin receptor activity(GO:0070287)
0.0 0.2 GO:0003835 beta-galactoside alpha-2,6-sialyltransferase activity(GO:0003835)
0.0 0.1 GO:0016418 S-acetyltransferase activity(GO:0016418)
0.0 1.5 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 0.2 GO:0048495 Roundabout binding(GO:0048495)
0.0 0.7 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.9 GO:0008137 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 0.1 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)
0.0 0.1 GO:0004661 protein geranylgeranyltransferase activity(GO:0004661)
0.0 0.4 GO:0003993 acid phosphatase activity(GO:0003993)
0.0 0.3 GO:0031432 titin binding(GO:0031432)
0.0 0.3 GO:0038191 neuropilin binding(GO:0038191)
0.0 2.6 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 2.4 GO:0042826 histone deacetylase binding(GO:0042826)
0.0 0.1 GO:0016435 rRNA (guanine) methyltransferase activity(GO:0016435)
0.0 0.4 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.0 1.8 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.1 ST WNT CA2 CYCLIC GMP PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.1 1.5 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 3.2 PID IGF1 PATHWAY IGF1 pathway
0.0 2.4 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II
0.0 1.3 PID ARF6 PATHWAY Arf6 signaling events
0.0 0.7 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 0.8 PID IL3 PATHWAY IL3-mediated signaling events
0.0 1.1 PID AURORA B PATHWAY Aurora B signaling
0.0 0.4 PID NFKAPPAB ATYPICAL PATHWAY Atypical NF-kappaB pathway
0.0 2.9 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.2 REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.0 0.9 REACTOME PLATELET CALCIUM HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.0 1.6 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.0 1.1 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 2.3 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 0.4 REACTOME SIGNAL ATTENUATION Genes involved in Signal attenuation
0.0 0.5 REACTOME CTLA4 INHIBITORY SIGNALING Genes involved in CTLA4 inhibitory signaling
0.0 0.2 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac