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GSE58827: Dynamics of the Mouse Liver

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Results for Hoxd12

Z-value: 0.64

Motif logo

Transcription factors associated with Hoxd12

Gene Symbol Gene ID Gene Info
ENSMUSG00000001823.6 homeobox D12

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Hoxd12mm39_v1_chr2_+_74505350_74505357-0.271.1e-01Click!

Activity profile of Hoxd12 motif

Sorted Z-values of Hoxd12 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr3_+_138121245 4.03 ENSMUST00000161312.8
ENSMUST00000013458.9
alcohol dehydrogenase 4 (class II), pi polypeptide
chr19_+_40078132 3.93 ENSMUST00000068094.13
ENSMUST00000080171.3
cytochrome P450, family 2, subfamily c, polypeptide 50
chr19_+_24853039 2.07 ENSMUST00000073080.7
predicted gene 10053
chr8_-_5155347 1.66 ENSMUST00000023835.3
solute carrier family 10, member 2
chrM_+_5319 1.35 ENSMUST00000082402.1
mitochondrially encoded cytochrome c oxidase I
chr8_-_70355208 1.08 ENSMUST00000110167.5
NADH:ubiquinone oxidoreductase subunit A13
chr7_+_123061535 1.05 ENSMUST00000098056.6
aquaporin 8
chr7_+_123061497 1.01 ENSMUST00000033023.10
aquaporin 8
chr2_+_155453103 0.97 ENSMUST00000092995.6
myosin, heavy chain 7B, cardiac muscle, beta
chr6_-_119365632 0.89 ENSMUST00000169744.8
adiponectin receptor 2
chr10_-_30531768 0.86 ENSMUST00000092610.12
nuclear receptor coactivator 7
chr4_+_43641262 0.86 ENSMUST00000123351.8
ENSMUST00000128549.3
natriuretic peptide receptor 2
chr17_+_3447465 0.83 ENSMUST00000072156.7
T cell lymphoma invasion and metastasis 2
chr16_+_42727926 0.78 ENSMUST00000151244.8
ENSMUST00000114694.9
zinc finger and BTB domain containing 20
chr10_-_30531832 0.76 ENSMUST00000217138.2
ENSMUST00000217644.2
ENSMUST00000216172.2
nuclear receptor coactivator 7
chr17_+_31652029 0.73 ENSMUST00000136384.9
phosphodiesterase 9A
chr16_-_35589726 0.73 ENSMUST00000023554.9
solute carrier family 49 member 4
chr1_-_57008986 0.73 ENSMUST00000176759.2
ENSMUST00000177424.2
special AT-rich sequence binding protein 2
chr16_+_11223512 0.70 ENSMUST00000096273.9
sorting nexin 29
chr17_+_31652073 0.70 ENSMUST00000237363.2
phosphodiesterase 9A
chr1_-_46927230 0.69 ENSMUST00000185520.2
solute carrier family 39 (zinc transporter), member 10
chr19_-_45800730 0.69 ENSMUST00000086993.11
Kv channel-interacting protein 2
chr4_+_31964082 0.68 ENSMUST00000037607.11
ENSMUST00000080933.13
ENSMUST00000108183.8
ENSMUST00000108184.3
mitogen-activated protein kinase kinase kinase 7
chr3_-_154036180 0.63 ENSMUST00000177846.8
LIM homeobox protein 8
chr13_-_23806530 0.63 ENSMUST00000062045.4
H1.4 linker histone, cluster member
chr14_-_68771138 0.62 ENSMUST00000022640.8
a disintegrin and metallopeptidase domain 7
chr10_+_43400074 0.60 ENSMUST00000057649.8
ENSMUST00000216543.2
predicted gene 9803
chr3_+_66893280 0.58 ENSMUST00000161726.2
ENSMUST00000160504.2
arginine/serine-rich coiled-coil 1
chr5_+_128677863 0.58 ENSMUST00000117102.4
frizzled class receptor 10
chr5_-_101812862 0.57 ENSMUST00000044125.11
NK6 homeobox 1
chr19_-_50667079 0.57 ENSMUST00000209413.2
ENSMUST00000072685.13
ENSMUST00000164039.9
sortilin-related VPS10 domain containing receptor 1
chrX_+_139357362 0.57 ENSMUST00000033809.4
phosphoribosyl pyrophosphate synthetase 1
chr3_+_75981577 0.56 ENSMUST00000038364.15
follistatin-like 5
chr1_+_46464625 0.56 ENSMUST00000189749.7
dynein, axonemal, heavy chain 7C
chr3_+_103482547 0.56 ENSMUST00000121834.8
synaptotagmin VI
chr3_+_103482591 0.56 ENSMUST00000090697.11
ENSMUST00000239027.2
synaptotagmin VI
chrM_+_3906 0.55 ENSMUST00000082396.1
mitochondrially encoded NADH dehydrogenase 2
chr7_+_43339842 0.53 ENSMUST00000056329.7
kallikrein related-peptidase 14
chr8_+_45960804 0.52 ENSMUST00000067065.14
ENSMUST00000124544.8
ENSMUST00000138049.9
ENSMUST00000132139.9
sorbin and SH3 domain containing 2
chr7_+_80863314 0.51 ENSMUST00000026672.8
phosphodiesterase 8A
chr6_+_71176811 0.50 ENSMUST00000067492.8
fatty acid binding protein 1, liver
chr1_-_176041498 0.50 ENSMUST00000111167.2
phospholipase D family, member 5
chr8_+_45960931 0.49 ENSMUST00000171337.10
ENSMUST00000067107.15
sorbin and SH3 domain containing 2
chr14_-_48900192 0.48 ENSMUST00000122009.8
orthodenticle homeobox 2
chr11_+_31823096 0.48 ENSMUST00000155278.2
cytoplasmic polyadenylation element binding protein 4
chr10_-_116732813 0.47 ENSMUST00000048229.9
myelin regulatory factor-like
chr7_+_89780785 0.47 ENSMUST00000208684.2
phosphatidylinositol binding clathrin assembly protein
chr10_+_34359395 0.46 ENSMUST00000019913.15
fyn-related kinase
chr18_-_3281727 0.46 ENSMUST00000154705.8
ENSMUST00000151084.8
cAMP responsive element modulator
chrX_-_142716085 0.46 ENSMUST00000087313.10
doublecortin
chr10_-_42459624 0.45 ENSMUST00000019938.11
nuclear receptor subfamily 2, group E, member 1
chr17_-_36207965 0.44 ENSMUST00000150056.2
ENSMUST00000156817.2
ENSMUST00000146451.8
ENSMUST00000148482.8
RIKEN cDNA 2310061I04 gene
chr10_+_23814470 0.44 ENSMUST00000079134.5
trace amine-associated receptor 2
chr8_-_47805383 0.44 ENSMUST00000110367.10
storkhead box 2
chr10_+_52267702 0.44 ENSMUST00000067085.7
nephrocan
chr15_+_8997480 0.44 ENSMUST00000227191.3
RAN binding protein 3-like
chr3_-_141637245 0.43 ENSMUST00000106232.8
bone morphogenetic protein receptor, type 1B
chr3_+_66893031 0.43 ENSMUST00000046542.13
ENSMUST00000162693.8
arginine/serine-rich coiled-coil 1
chr9_-_89620461 0.42 ENSMUST00000060700.4
ENSMUST00000185470.3
ankyrin repeat domain 34C
chr17_-_91400142 0.42 ENSMUST00000160800.9
neurexin I
chr8_-_25528972 0.41 ENSMUST00000084031.6
HtrA serine peptidase 4
chr10_-_67972401 0.40 ENSMUST00000218532.2
AT rich interactive domain 5B (MRF1-like)
chr2_+_57887896 0.40 ENSMUST00000112616.8
ENSMUST00000166729.2
polypeptide N-acetylgalactosaminyltransferase 5
chr1_+_128069716 0.39 ENSMUST00000187557.2
R3H domain containing 1
chr13_-_21826688 0.39 ENSMUST00000205631.3
olfactory receptor 11
chr10_-_25076008 0.39 ENSMUST00000100012.3
A kinase (PRKA) anchor protein 7
chr19_+_22425565 0.39 ENSMUST00000037901.14
transient receptor potential cation channel, subfamily M, member 3
chr10_+_4561974 0.39 ENSMUST00000105590.8
ENSMUST00000067086.14
estrogen receptor 1 (alpha)
chr9_+_45230370 0.38 ENSMUST00000034597.8
transmembrane protease, serine 13
chr17_-_52133594 0.38 ENSMUST00000129667.8
ENSMUST00000169480.8
ENSMUST00000148559.2
special AT-rich sequence binding protein 1
chr4_-_83203388 0.38 ENSMUST00000150522.8
tetratricopeptide repeat domain 39B
chr1_-_165762469 0.37 ENSMUST00000069609.12
ENSMUST00000111427.9
ENSMUST00000111426.11
POU domain, class 2, transcription factor 1
chr5_+_142678212 0.36 ENSMUST00000198728.5
solute carrier family 29 (nucleoside transporters), member 4
chr18_-_20135139 0.35 ENSMUST00000115848.5
desmocollin 3
chr18_-_20135012 0.35 ENSMUST00000225110.2
desmocollin 3
chr10_+_34359513 0.35 ENSMUST00000170771.3
fyn-related kinase
chr2_-_103114105 0.35 ENSMUST00000111174.8
ets homologous factor
chr7_+_5017414 0.34 ENSMUST00000207901.2
zinc finger protein 524
chrX_-_142716200 0.34 ENSMUST00000112851.8
ENSMUST00000112856.3
ENSMUST00000033642.10
doublecortin
chr13_-_43632368 0.34 ENSMUST00000222651.2
RAN binding protein 9
chr11_-_46581135 0.34 ENSMUST00000169584.8
T cell immunoglobulin and mucin domain containing 2
chr5_-_25047577 0.34 ENSMUST00000030787.9
Ras homolog enriched in brain
chr1_+_132128701 0.34 ENSMUST00000189062.2
LEM domain containing 1
chr17_-_36208265 0.33 ENSMUST00000148721.8
RIKEN cDNA 2310061I04 gene
chr10_+_116013256 0.33 ENSMUST00000155606.8
ENSMUST00000128399.2
protein tyrosine phosphatase, receptor type, R
chr18_-_20135396 0.33 ENSMUST00000223946.2
desmocollin 3
chr4_-_154721288 0.33 ENSMUST00000030902.13
ENSMUST00000105637.8
ENSMUST00000070313.14
ENSMUST00000105636.8
ENSMUST00000105638.9
ENSMUST00000097759.9
ENSMUST00000124771.2
PR domain containing 16
chr10_+_116013122 0.33 ENSMUST00000148731.8
protein tyrosine phosphatase, receptor type, R
chr5_-_65855511 0.33 ENSMUST00000201948.4
PDS5 cohesin associated factor A
chr11_-_88608958 0.32 ENSMUST00000107908.2
musashi RNA-binding protein 2
chr3_+_66892979 0.32 ENSMUST00000162362.8
ENSMUST00000065074.14
ENSMUST00000065047.13
arginine/serine-rich coiled-coil 1
chrX_+_35459557 0.32 ENSMUST00000115258.9
zinc finger, CCHC domain containing 12
chr14_-_52011035 0.32 ENSMUST00000073860.6
angiogenin, ribonuclease A family, member 4
chr16_-_89305201 0.32 ENSMUST00000056118.4
keratin associated protein 7-1
chr17_+_35235552 0.31 ENSMUST00000007245.8
ENSMUST00000172499.2
von Willebrand factor A domain containing 7
chr14_-_118289557 0.31 ENSMUST00000022725.4
dopachrome tautomerase
chr7_+_30264835 0.31 ENSMUST00000043850.14
IGF-like family receptor 1
chr11_-_42070517 0.31 ENSMUST00000206105.2
ENSMUST00000153147.3
gamma-aminobutyric acid (GABA) A receptor, subunit alpha 1
chr9_+_40092216 0.31 ENSMUST00000218134.2
ENSMUST00000216720.2
ENSMUST00000214763.2
olfactory receptor 986
chrX_+_35459621 0.31 ENSMUST00000115256.2
zinc finger, CCHC domain containing 12
chrX_+_35459589 0.30 ENSMUST00000048067.10
zinc finger, CCHC domain containing 12
chr15_+_25774070 0.30 ENSMUST00000125667.3
myosin X
chr1_-_69147185 0.30 ENSMUST00000121473.8
erb-b2 receptor tyrosine kinase 4
chr1_+_163875783 0.30 ENSMUST00000027874.6
selectin, endothelial cell
chr15_-_8739893 0.29 ENSMUST00000157065.2
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chrX_+_35459601 0.29 ENSMUST00000115257.8
zinc finger, CCHC domain containing 12
chr13_-_53627110 0.29 ENSMUST00000021922.10
msh homeobox 2
chr5_-_148489593 0.29 ENSMUST00000201595.4
ENSMUST00000164904.2
ubiquitin-like 3
chr9_-_14815050 0.28 ENSMUST00000148155.2
ENSMUST00000121116.8
IZUMO1 receptor, JUNO
chr14_-_67106037 0.28 ENSMUST00000022629.9
dihydropyrimidinase-like 2
chr14_+_31807760 0.28 ENSMUST00000170600.8
ENSMUST00000168986.7
ENSMUST00000169649.2
oxidoreductase NAD-binding domain containing 1
chr10_-_80257681 0.27 ENSMUST00000156244.2
transcription factor 3
chrX_-_71961890 0.27 ENSMUST00000152200.2
centrin 2
chr17_+_72088281 0.27 ENSMUST00000229874.2
CAP-GLY domain containing linker protein family, member 4
chr1_+_6805048 0.27 ENSMUST00000139838.8
suppression of tumorigenicity 18
chr9_+_65268304 0.27 ENSMUST00000147185.3
ubiquitin-associated protein 1-like
chr12_+_33197776 0.27 ENSMUST00000125192.9
ENSMUST00000136644.8
ataxin 7-like 1
chr11_-_99996452 0.27 ENSMUST00000107416.3
keratin 36
chr1_+_128069677 0.27 ENSMUST00000187023.7
R3H domain containing 1
chr16_-_56616186 0.26 ENSMUST00000023437.5
adhesion G protein-coupled receptor G7
chr16_+_57173632 0.26 ENSMUST00000099667.3
filamin A interacting protein 1-like
chr1_+_82817794 0.26 ENSMUST00000186043.2
ArfGAP with FG repeats 1
chr19_+_26725589 0.26 ENSMUST00000207812.2
ENSMUST00000175791.9
ENSMUST00000207118.2
ENSMUST00000209085.2
ENSMUST00000112637.10
ENSMUST00000207054.2
ENSMUST00000208589.2
ENSMUST00000176475.9
ENSMUST00000176698.9
ENSMUST00000207832.2
ENSMUST00000177252.9
ENSMUST00000208712.2
ENSMUST00000208186.2
ENSMUST00000208806.2
ENSMUST00000208027.2
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr11_-_43492367 0.26 ENSMUST00000020672.5
fatty acid binding protein 6
chr9_-_14815163 0.26 ENSMUST00000069408.10
IZUMO1 receptor, JUNO
chr19_+_60744385 0.25 ENSMUST00000088237.6
nanos C2HC-type zinc finger 1
chrX_-_103244728 0.25 ENSMUST00000056502.7
neurite extension and migration factor
chr11_+_29413734 0.25 ENSMUST00000155854.8
coiled coil domain containing 88A
chr9_-_123778334 0.24 ENSMUST00000071404.5
chemokine (C-C motif) receptor 1-like 1
chr15_-_34356567 0.24 ENSMUST00000179647.2
RIKEN cDNA 9430069I07 gene
chr2_+_48839505 0.24 ENSMUST00000112745.8
ENSMUST00000112754.8
methyl-CpG binding domain protein 5
chr3_-_26386609 0.24 ENSMUST00000193603.6
neuroligin 1
chr10_+_19232281 0.23 ENSMUST00000053225.7
oligodendrocyte transcription factor 3
chr14_-_31807552 0.23 ENSMUST00000022461.11
ENSMUST00000067955.12
ENSMUST00000124303.9
diphthamine biosynthesis 3
chr12_+_33197692 0.23 ENSMUST00000077456.13
ENSMUST00000110824.9
ataxin 7-like 1
chrX_-_103244784 0.23 ENSMUST00000118314.8
neurite extension and migration factor
chr1_-_37535170 0.23 ENSMUST00000148047.2
mannoside acetylglucosaminyltransferase 4, isoenzyme A
chr12_+_33197753 0.22 ENSMUST00000146040.9
ataxin 7-like 1
chr14_-_36641270 0.22 ENSMUST00000182797.8
coiled-coil serine rich 2
chr5_-_74692327 0.22 ENSMUST00000072857.13
ENSMUST00000113542.9
ENSMUST00000151474.3
Sec1 family domain containing 2
chr1_+_173986288 0.22 ENSMUST00000068403.4
olfactory receptor 420
chr14_-_36641470 0.21 ENSMUST00000182042.2
coiled-coil serine rich 2
chr18_-_3281752 0.21 ENSMUST00000140332.8
ENSMUST00000147138.8
cAMP responsive element modulator
chr1_-_37535202 0.21 ENSMUST00000143636.8
mannoside acetylglucosaminyltransferase 4, isoenzyme A
chr18_-_35348049 0.21 ENSMUST00000091636.5
ENSMUST00000236680.2
leucine rich repeat transmembrane neuronal 2
chr4_-_82423985 0.20 ENSMUST00000107245.9
ENSMUST00000107246.2
nuclear factor I/B
chr3_-_19217174 0.20 ENSMUST00000029125.10
armadillo repeat containing 1
chr17_-_45047521 0.20 ENSMUST00000113572.9
runt related transcription factor 2
chr10_+_119828821 0.20 ENSMUST00000105261.9
glutamate receptor interacting protein 1
chr6_+_15185202 0.20 ENSMUST00000154448.2
forkhead box P2
chr11_-_101785181 0.20 ENSMUST00000057054.8
mesenchyme homeobox 1
chr5_-_28672091 0.19 ENSMUST00000002708.5
sonic hedgehog
chr3_-_64049349 0.19 ENSMUST00000177151.9
vomeronasal 2, receptor 2
chr9_-_77255171 0.19 ENSMUST00000185039.8
muscular LMNA-interacting protein
chr2_-_35994819 0.19 ENSMUST00000148852.4
LIM homeobox protein 6
chr4_+_148085179 0.19 ENSMUST00000103230.5
natriuretic peptide type A
chr10_-_107321938 0.18 ENSMUST00000000445.2
myogenic factor 5
chrX_+_159551009 0.18 ENSMUST00000033650.14
retinoschisis (X-linked, juvenile) 1 (human)
chr9_+_109641348 0.17 ENSMUST00000200555.5
serine peptidase inhibitor, Kazal type 8
chr16_-_50252703 0.17 ENSMUST00000066037.13
ENSMUST00000089399.11
ENSMUST00000089404.10
ENSMUST00000138166.8
bobby sox HMG box containing
chr2_-_18053595 0.16 ENSMUST00000142856.2
SKI/DACH domain containing 1
chr12_+_55883101 0.16 ENSMUST00000059250.8
breast cancer metastasis-suppressor 1-like
chr7_-_102408573 0.16 ENSMUST00000210453.3
ENSMUST00000232246.3
ENSMUST00000239110.2
ENSMUST00000060187.15
ENSMUST00000168007.3
olfactory receptor 560
olfactory receptor 78
chr6_+_15185562 0.16 ENSMUST00000137628.8
forkhead box P2
chrX_-_49108236 0.16 ENSMUST00000213556.3
ENSMUST00000213463.2
olfactory receptor 1323
chr17_-_47169380 0.16 ENSMUST00000233455.2
BRD4 interacting chromatin remodeling complex associated protein like
chr4_-_82423944 0.16 ENSMUST00000107248.8
ENSMUST00000107247.8
nuclear factor I/B
chr8_+_45960855 0.16 ENSMUST00000141039.8
sorbin and SH3 domain containing 2
chr3_-_117153802 0.15 ENSMUST00000197743.2
phospholipid phosphatase related 4
chr15_+_81821112 0.15 ENSMUST00000135663.2
cold shock domain containing C2, RNA binding
chr2_+_85822163 0.15 ENSMUST00000050942.3
olfactory receptor 1031
chr8_+_70354828 0.15 ENSMUST00000050373.7
testis-specific serine kinase 6
chr10_+_87926932 0.14 ENSMUST00000048621.8
pro-melanin-concentrating hormone
chr2_+_111327525 0.14 ENSMUST00000121345.4
olfactory receptor 1291, pseudogene 1
chr5_+_18167547 0.14 ENSMUST00000030561.9
guanine nucleotide binding protein, alpha transducing 3
chr13_-_3995349 0.14 ENSMUST00000058610.8
urocortin 3
chr18_-_84854841 0.14 ENSMUST00000236689.2
predicted gene, 17266
chr6_+_90179768 0.14 ENSMUST00000078371.6
vomeronasal 1 receptor, A8
chr1_+_59296065 0.13 ENSMUST00000160662.8
ENSMUST00000114248.3
cyclin-dependent kinase 15
chr15_+_36179676 0.13 ENSMUST00000171205.3
sperm associated antigen 1
chr9_+_43222104 0.13 ENSMUST00000034511.7
tripartite motif-containing 29
chr2_+_73102269 0.13 ENSMUST00000090813.6
trans-acting transcription factor 9
chr4_-_82423511 0.12 ENSMUST00000050872.15
ENSMUST00000064770.9
nuclear factor I/B
chr12_-_69838004 0.11 ENSMUST00000221646.2
cyclin-dependent kinase-like 1 (CDC2-related kinase)
chr7_+_103379581 0.11 ENSMUST00000098193.4
olfactory receptor 628
chr15_-_8740218 0.11 ENSMUST00000005493.14
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr14_+_26616514 0.11 ENSMUST00000238987.2
ENSMUST00000239004.2
ENSMUST00000165929.4
ENSMUST00000090337.12
ankyrin repeat and SOCS box-containing 14
chr14_+_53048391 0.11 ENSMUST00000103646.5
T cell receptor alpha variable 10D
chr2_-_45007407 0.10 ENSMUST00000176438.9
zinc finger E-box binding homeobox 2
chr5_+_143864993 0.10 ENSMUST00000172367.3
predicted gene, 42421
chr6_+_136528155 0.10 ENSMUST00000186742.2
activating transcription factor 7 interacting protein
chr6_+_15185399 0.09 ENSMUST00000115474.8
ENSMUST00000115472.8
ENSMUST00000031545.14
forkhead box P2
chr2_+_65676176 0.09 ENSMUST00000053910.10
cysteine-serine-rich nuclear protein 3
chrX_+_159551171 0.09 ENSMUST00000112368.3
retinoschisis (X-linked, juvenile) 1 (human)
chr13_+_83672389 0.09 ENSMUST00000200394.5
myocyte enhancer factor 2C
chr9_+_110948492 0.09 ENSMUST00000217341.3
leucine rich repeat (in FLII) interacting protein 2
chr9_-_123507937 0.08 ENSMUST00000040960.13
solute carrier family 6 (neurotransmitter transporter), member 20A
chr6_-_38230890 0.08 ENSMUST00000117556.8
ENSMUST00000169256.5
RIKEN cDNA D630045J12 gene
chr9_-_14815228 0.08 ENSMUST00000034409.14
ENSMUST00000117620.8
IZUMO1 receptor, JUNO
chr4_+_136012019 0.08 ENSMUST00000130223.8
zinc finger protein 46

Network of associatons between targets according to the STRING database.

First level regulatory network of Hoxd12

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 4.0 GO:0006069 ethanol oxidation(GO:0006069)
0.3 3.9 GO:0043651 linoleic acid metabolic process(GO:0043651)
0.3 2.1 GO:0015722 canalicular bile acid transport(GO:0015722)
0.2 1.1 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
0.2 1.2 GO:2000325 regulation of ligand-dependent nuclear receptor transcription coactivator activity(GO:2000325) positive regulation of ligand-dependent nuclear receptor transcription coactivator activity(GO:2000327)
0.2 0.6 GO:0046100 hypoxanthine metabolic process(GO:0046100) hypoxanthine biosynthetic process(GO:0046101)
0.2 1.1 GO:0060478 acrosomal vesicle exocytosis(GO:0060478)
0.1 0.5 GO:2000795 negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
0.1 0.7 GO:0045163 clustering of voltage-gated potassium channels(GO:0045163)
0.1 0.7 GO:0097343 ripoptosome assembly(GO:0097343) ripoptosome assembly involved in necroptotic process(GO:1901026)
0.1 0.7 GO:0038128 ERBB2 signaling pathway(GO:0038128)
0.1 0.4 GO:0046604 positive regulation of mitotic centrosome separation(GO:0046604)
0.1 1.0 GO:0007168 receptor guanylyl cyclase signaling pathway(GO:0007168)
0.1 0.3 GO:0006583 melanin biosynthetic process from tyrosine(GO:0006583)
0.1 0.3 GO:2001055 positive regulation of mesenchymal cell apoptotic process(GO:2001055)
0.1 0.6 GO:0060523 prostate epithelial cord elongation(GO:0060523)
0.1 0.6 GO:0021912 regulation of transcription from RNA polymerase II promoter involved in spinal cord motor neuron fate specification(GO:0021912) regulation of transcription from RNA polymerase II promoter involved in ventral spinal cord interneuron specification(GO:0021913)
0.1 0.7 GO:0021902 commitment of neuronal cell to specific neuron type in forebrain(GO:0021902)
0.1 0.4 GO:0048165 ovarian cumulus expansion(GO:0001550) fused antrum stage(GO:0048165)
0.1 1.6 GO:1902083 negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.1 1.4 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.1 0.3 GO:0098749 cerebellar neuron development(GO:0098749)
0.1 0.4 GO:0043490 malate-aspartate shuttle(GO:0043490)
0.1 0.5 GO:0042706 eye photoreceptor cell fate commitment(GO:0042706) photoreceptor cell fate commitment(GO:0046552)
0.1 0.5 GO:1902963 regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902962) negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902963)
0.1 0.2 GO:0048789 cytoskeletal matrix organization at active zone(GO:0048789) neurexin clustering involved in presynaptic membrane assembly(GO:0097115) retrograde trans-synaptic signaling by trans-synaptic protein complex(GO:0098942)
0.1 0.4 GO:1902261 positive regulation of delayed rectifier potassium channel activity(GO:1902261)
0.1 0.4 GO:0021960 amygdala development(GO:0021764) anterior commissure morphogenesis(GO:0021960) regulation of timing of neuron differentiation(GO:0060164)
0.1 0.3 GO:0061026 cardiac muscle tissue regeneration(GO:0061026)
0.1 0.8 GO:0061042 vascular wound healing(GO:0061042)
0.1 0.6 GO:0038031 non-canonical Wnt signaling pathway via JNK cascade(GO:0038031)
0.1 0.4 GO:0090126 protein complex assembly involved in synapse maturation(GO:0090126)
0.1 1.7 GO:0015721 bile acid and bile salt transport(GO:0015721)
0.1 0.3 GO:0036367 adaptation of rhodopsin mediated signaling(GO:0016062) light adaption(GO:0036367)
0.1 1.4 GO:0046069 cGMP catabolic process(GO:0046069)
0.1 0.4 GO:0071699 olfactory placode formation(GO:0030910) olfactory placode development(GO:0071698) olfactory placode morphogenesis(GO:0071699)
0.1 0.7 GO:0050861 positive regulation of B cell receptor signaling pathway(GO:0050861)
0.1 0.2 GO:0060399 positive regulation of growth hormone receptor signaling pathway(GO:0060399)
0.1 0.2 GO:1900135 positive regulation of renin secretion into blood stream(GO:1900135)
0.0 0.1 GO:0046005 positive regulation of circadian sleep/wake cycle, REM sleep(GO:0046005)
0.0 0.2 GO:0097476 spinal cord motor neuron migration(GO:0097476)
0.0 0.8 GO:0048672 positive regulation of collateral sprouting(GO:0048672)
0.0 0.5 GO:2000766 negative regulation of cytoplasmic translation(GO:2000766)
0.0 0.6 GO:0007342 fusion of sperm to egg plasma membrane(GO:0007342)
0.0 0.2 GO:1903566 positive regulation of protein localization to cilium(GO:1903566)
0.0 0.2 GO:0061056 sclerotome development(GO:0061056)
0.0 0.4 GO:0060501 positive regulation of epithelial cell proliferation involved in lung morphogenesis(GO:0060501)
0.0 0.3 GO:0002326 B cell lineage commitment(GO:0002326)
0.0 0.6 GO:0036159 inner dynein arm assembly(GO:0036159)
0.0 0.3 GO:0035887 aortic smooth muscle cell differentiation(GO:0035887)
0.0 0.5 GO:0032000 positive regulation of fatty acid beta-oxidation(GO:0032000)
0.0 0.3 GO:2000074 regulation of type B pancreatic cell development(GO:2000074)
0.0 0.5 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.0 0.4 GO:0007320 insemination(GO:0007320)
0.0 0.2 GO:0048743 positive regulation of skeletal muscle fiber development(GO:0048743)
0.0 1.4 GO:0046677 response to antibiotic(GO:0046677)
0.0 0.1 GO:0050916 sensory perception of sweet taste(GO:0050916) sensory perception of umami taste(GO:0050917)
0.0 0.1 GO:0035524 proline transmembrane transport(GO:0035524)
0.0 0.3 GO:0090336 positive regulation of brown fat cell differentiation(GO:0090336)
0.0 1.2 GO:0003298 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.0 0.4 GO:0043374 CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.0 0.1 GO:0035660 MyD88-dependent toll-like receptor 4 signaling pathway(GO:0035660)
0.0 0.3 GO:2001269 positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:2001269)
0.0 0.2 GO:0002051 osteoblast fate commitment(GO:0002051)
0.0 0.8 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.0 0.3 GO:0071420 cellular response to histamine(GO:0071420)
0.0 0.5 GO:1903206 negative regulation of hydrogen peroxide-induced cell death(GO:1903206)
0.0 0.1 GO:1902748 positive regulation of lens fiber cell differentiation(GO:1902748)
0.0 0.4 GO:0061436 establishment of skin barrier(GO:0061436)
0.0 0.2 GO:1900003 regulation of serine-type endopeptidase activity(GO:1900003) negative regulation of serine-type endopeptidase activity(GO:1900004) regulation of serine-type peptidase activity(GO:1902571) negative regulation of serine-type peptidase activity(GO:1902572)
0.0 0.4 GO:0007289 spermatid nucleus differentiation(GO:0007289)
0.0 0.3 GO:0043162 ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043162)
0.0 0.0 GO:1904499 regulation of chromatin-mediated maintenance of transcription(GO:1904499) positive regulation of chromatin-mediated maintenance of transcription(GO:1904501) regulation of euchromatin binding(GO:1904793)
0.0 0.1 GO:0097118 neuroligin clustering involved in postsynaptic membrane assembly(GO:0097118)
0.0 0.1 GO:0048478 replication fork protection(GO:0048478)
0.0 0.3 GO:0014049 positive regulation of glutamate secretion(GO:0014049)
0.0 0.4 GO:0030325 adrenal gland development(GO:0030325)
0.0 0.3 GO:0007202 activation of phospholipase C activity(GO:0007202)
0.0 0.2 GO:0002091 negative regulation of receptor internalization(GO:0002091)
0.0 0.2 GO:0090026 positive regulation of monocyte chemotaxis(GO:0090026)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 2.1 GO:0046691 intracellular canaliculus(GO:0046691)
0.1 0.6 GO:0002189 ribose phosphate diphosphokinase complex(GO:0002189)
0.1 1.4 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.1 0.3 GO:0071942 XPC complex(GO:0071942)
0.1 0.5 GO:0070381 endosome to plasma membrane transport vesicle(GO:0070381)
0.1 0.4 GO:0097550 transcriptional preinitiation complex(GO:0097550)
0.1 1.0 GO:0097512 cardiac myofibril(GO:0097512)
0.0 0.5 GO:0045179 apical cortex(GO:0045179)
0.0 0.6 GO:0036156 inner dynein arm(GO:0036156)
0.0 0.9 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.0 1.0 GO:0030057 desmosome(GO:0030057)
0.0 1.1 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.0 0.5 GO:0036056 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.0 0.5 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.0 0.3 GO:0000788 nuclear nucleosome(GO:0000788)
0.0 0.5 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.0 1.1 GO:0045271 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 0.5 GO:0070469 respiratory chain(GO:0070469)
0.0 0.3 GO:0000813 ESCRT I complex(GO:0000813)
0.0 0.2 GO:0042629 mast cell granule(GO:0042629)
0.0 1.7 GO:0000502 proteasome complex(GO:0000502)
0.0 0.4 GO:0005614 interstitial matrix(GO:0005614)
0.0 0.3 GO:1902711 GABA-A receptor complex(GO:1902711)
0.0 0.2 GO:0032433 filopodium tip(GO:0032433)
0.0 0.3 GO:0071564 npBAF complex(GO:0071564)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 4.0 GO:0004024 alcohol dehydrogenase activity, zinc-dependent(GO:0004024)
1.0 3.9 GO:0071614 linoleic acid epoxygenase activity(GO:0071614)
0.2 1.7 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.2 0.9 GO:0097003 adipokinetic hormone receptor activity(GO:0097003)
0.1 0.9 GO:0016941 natriuretic peptide receptor activity(GO:0016941)
0.1 0.6 GO:0004749 ribose phosphate diphosphokinase activity(GO:0004749)
0.1 0.7 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.1 0.4 GO:0038052 type 1 metabotropic glutamate receptor binding(GO:0031798) RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding(GO:0038052)
0.1 2.1 GO:0015250 water channel activity(GO:0015250)
0.1 0.8 GO:0032052 bile acid binding(GO:0032052)
0.1 0.3 GO:0070287 ferritin receptor activity(GO:0070287)
0.1 0.4 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.1 0.4 GO:0001594 trace-amine receptor activity(GO:0001594)
0.1 0.3 GO:0030280 structural constituent of epidermis(GO:0030280)
0.1 1.6 GO:0008137 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 1.4 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555)
0.0 0.1 GO:0051431 corticotropin-releasing hormone receptor 2 binding(GO:0051431)
0.0 0.3 GO:0070644 vitamin D response element binding(GO:0070644)
0.0 0.4 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.0 0.3 GO:1904315 transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315)
0.0 0.6 GO:0070492 oligosaccharide binding(GO:0070492)
0.0 0.4 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.0 1.2 GO:0032183 SUMO binding(GO:0032183)
0.0 0.3 GO:0004716 receptor signaling protein tyrosine kinase activity(GO:0004716)
0.0 0.5 GO:0032050 clathrin heavy chain binding(GO:0032050)
0.0 0.4 GO:0008504 monoamine transmembrane transporter activity(GO:0008504)
0.0 0.3 GO:0032795 heterotrimeric G-protein binding(GO:0032795)
0.0 0.4 GO:0097109 neuroligin family protein binding(GO:0097109)
0.0 0.4 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 0.8 GO:0004129 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 0.7 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.0 0.5 GO:0000900 translation repressor activity, nucleic acid binding(GO:0000900)
0.0 0.6 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.7 GO:0045295 gamma-catenin binding(GO:0045295)
0.0 0.6 GO:0005542 folic acid binding(GO:0005542)
0.0 0.4 GO:0016208 AMP binding(GO:0016208)
0.0 0.6 GO:0008569 ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569)
0.0 0.4 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0 0.2 GO:0005113 patched binding(GO:0005113)
0.0 0.7 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 1.0 GO:0001786 phosphatidylserine binding(GO:0001786)
0.0 0.5 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 0.3 GO:0016863 intramolecular oxidoreductase activity, transposing C=C bonds(GO:0016863)
0.0 0.8 GO:0008536 Ran GTPase binding(GO:0008536)
0.0 0.4 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.0 0.7 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.0 0.2 GO:0016493 C-C chemokine receptor activity(GO:0016493)
0.0 0.1 GO:0031697 beta-1 adrenergic receptor binding(GO:0031697)
0.0 0.5 GO:0000983 transcription factor activity, RNA polymerase II core promoter sequence-specific(GO:0000983)
0.0 0.0 GO:0004574 oligo-1,6-glucosidase activity(GO:0004574)
0.0 0.2 GO:0051959 dynein light intermediate chain binding(GO:0051959)
0.0 0.8 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.0 0.2 GO:0042577 lipid phosphatase activity(GO:0042577)
0.0 0.3 GO:0008266 poly(U) RNA binding(GO:0008266)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.7 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.0 2.1 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.0 1.1 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 1.6 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network
0.0 0.6 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 0.8 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.0 0.7 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.0 0.3 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.0 1.4 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 4.0 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.2 1.9 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.1 2.1 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.1 0.7 REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.0 1.4 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.0 0.7 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.0 0.3 REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.0 0.9 REACTOME RNA POL III TRANSCRIPTION Genes involved in RNA Polymerase III Transcription
0.0 0.4 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.0 0.6 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.0 1.1 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.0 0.3 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.0 0.4 REACTOME AMINE LIGAND BINDING RECEPTORS Genes involved in Amine ligand-binding receptors
0.0 0.3 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.0 1.3 REACTOME PPARA ACTIVATES GENE EXPRESSION Genes involved in PPARA Activates Gene Expression