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GSE58827: Dynamics of the Mouse Liver

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Results for Hoxd8

Z-value: 0.79

Motif logo

Transcription factors associated with Hoxd8

Gene Symbol Gene ID Gene Info
ENSMUSG00000027102.5 homeobox D8

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Hoxd8mm39_v1_chr2_+_74535489_74535500-0.231.8e-01Click!

Activity profile of Hoxd8 motif

Sorted Z-values of Hoxd8 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr6_+_121983720 9.00 ENSMUST00000081777.8
murinoglobulin 2
chr19_-_46661321 4.41 ENSMUST00000026012.8
cytochrome P450, family 17, subfamily a, polypeptide 1
chr7_+_140343652 4.24 ENSMUST00000026552.9
ENSMUST00000209253.2
ENSMUST00000210235.2
cytochrome P450, family 2, subfamily e, polypeptide 1
chr19_-_46661501 4.12 ENSMUST00000236174.2
cytochrome P450, family 17, subfamily a, polypeptide 1
chr10_-_127843377 3.49 ENSMUST00000219447.2
ENSMUST00000219780.2
ENSMUST00000219707.2
ENSMUST00000219953.2
ENSMUST00000219183.2
hydroxysteroid (17-beta) dehydrogenase 6
chr18_-_38999755 3.35 ENSMUST00000115582.8
ENSMUST00000236060.2
fibroblast growth factor 1
chr1_+_88093726 3.06 ENSMUST00000097659.5
UDP glucuronosyltransferase 1 family, polypeptide A5
chr5_+_87148697 2.93 ENSMUST00000031186.9
UDP glucuronosyltransferase 2 family, polypeptide B35
chr19_-_39637489 2.75 ENSMUST00000067328.7
cytochrome P450, family 2, subfamily c, polypeptide 67
chr1_+_9618173 2.66 ENSMUST00000144177.8
alcohol dehydrogenase, iron containing, 1
chr9_+_80072274 2.59 ENSMUST00000035889.15
ENSMUST00000113268.8
myosin VI
chr14_+_55797443 2.46 ENSMUST00000117236.8
DDB1 and CUL4 associated factor 11
chr3_+_94280101 2.38 ENSMUST00000029795.10
RAR-related orphan receptor gamma
chr9_+_80072361 2.11 ENSMUST00000184480.8
myosin VI
chr1_+_180878797 2.09 ENSMUST00000036819.7
RIKEN cDNA 9130409I23 gene
chr14_+_55797468 2.07 ENSMUST00000147981.2
ENSMUST00000133256.8
DDB1 and CUL4 associated factor 11
chr18_-_39000056 1.92 ENSMUST00000236630.2
ENSMUST00000237356.2
fibroblast growth factor 1
chr15_-_96929086 1.88 ENSMUST00000230086.2
solute carrier family 38, member 4
chr9_-_15212849 1.84 ENSMUST00000034414.10
RIKEN cDNA 4931406C07 gene
chr11_+_117700479 1.82 ENSMUST00000026649.14
ENSMUST00000177131.8
ENSMUST00000120928.2
ENSMUST00000175737.2
ENSMUST00000132298.2
synaptogyrin 2
predicted gene 20708
chr13_+_24023428 1.76 ENSMUST00000091698.12
ENSMUST00000110422.3
ENSMUST00000166467.9
solute carrier family 17 (sodium phosphate), member 3
chr13_-_63036096 1.71 ENSMUST00000092888.11
fructose bisphosphatase 1
chr7_-_12829100 1.67 ENSMUST00000209822.3
ENSMUST00000235753.2
vomeronasal 1 receptor 85
chr3_+_142300601 1.66 ENSMUST00000029936.5
guanylate binding protein 2b
chr1_+_87983099 1.54 ENSMUST00000138182.8
ENSMUST00000113142.10
UDP glycosyltransferase 1 family, polypeptide A10
chr17_+_79919267 1.41 ENSMUST00000223924.2
regulator of microtubule dynamics 2
chr13_+_24023386 1.35 ENSMUST00000039721.14
solute carrier family 17 (sodium phosphate), member 3
chr2_+_152511381 1.33 ENSMUST00000125366.8
ENSMUST00000109825.8
ENSMUST00000089059.9
ENSMUST00000079247.4
histocompatibility 13
chr1_+_87983189 1.22 ENSMUST00000173325.2
UDP glycosyltransferase 1 family, polypeptide A10
chr9_+_21634779 1.21 ENSMUST00000034713.9
low density lipoprotein receptor
chr7_-_44711771 1.14 ENSMUST00000210101.2
ENSMUST00000209219.2
proline-rich Gla (G-carboxyglutamic acid) polypeptide 2
chr7_-_99629637 1.09 ENSMUST00000080817.6
ring finger protein 169
chr17_+_44114894 1.02 ENSMUST00000044895.13
regulator of calcineurin 2
chr3_-_75177378 1.02 ENSMUST00000039047.5
serine (or cysteine) peptidase inhibitor, clade I, member 2
chr12_-_25147139 0.93 ENSMUST00000221761.2
inhibitor of DNA binding 2
chr3_+_20011405 0.93 ENSMUST00000108325.9
ceruloplasmin
chr11_-_59466995 0.91 ENSMUST00000215339.2
ENSMUST00000214351.2
olfactory receptor 222
chr1_-_138776315 0.90 ENSMUST00000112030.9
LIM homeobox protein 9
chr5_+_29400981 0.90 ENSMUST00000160888.8
ENSMUST00000159272.8
ENSMUST00000001247.12
ENSMUST00000161398.8
ENSMUST00000160246.8
ring finger protein 32
chr7_+_130633776 0.85 ENSMUST00000084509.7
ENSMUST00000213064.3
ENSMUST00000208311.4
deleted in malignant brain tumors 1
chr2_-_86208737 0.85 ENSMUST00000217435.2
olfactory receptor 1057
chr4_-_108158242 0.80 ENSMUST00000043616.7
zyg-ll family member B, cell cycle regulator
chr6_+_137387729 0.80 ENSMUST00000203914.2
protein tyrosine phosphatase, receptor type, O
chr17_+_46807637 0.78 ENSMUST00000046497.8
2'-deoxynucleoside 5'-phosphate N-hydrolase 1
chr16_+_11224481 0.75 ENSMUST00000122168.8
sorting nexin 29
chr11_+_77928736 0.74 ENSMUST00000072289.12
ENSMUST00000100784.9
ENSMUST00000073660.7
flotillin 2
chr3_-_19319123 0.73 ENSMUST00000121951.2
phosphodiesterase 7A
chr17_+_34866160 0.68 ENSMUST00000173984.2
activating transcription factor 6 beta
chr9_-_55419442 0.63 ENSMUST00000034866.9
electron transferring flavoprotein, alpha polypeptide
chr15_-_103473481 0.61 ENSMUST00000228060.2
ENSMUST00000228895.2
ENSMUST00000023134.5
glycosylation dependent cell adhesion molecule 1
chr2_+_81883566 0.60 ENSMUST00000047527.8
zinc finger protein 804A
chr2_-_163314480 0.59 ENSMUST00000109418.2
fat storage-inducing transmembrane protein 2
chr7_+_43077088 0.58 ENSMUST00000239023.2
predicted gene, 38999
chr2_+_151336197 0.58 ENSMUST00000028949.16
ENSMUST00000103160.5
NSFL1 (p97) cofactor (p47)
chr1_+_178233640 0.57 ENSMUST00000027775.9
EF-hand calcium binding domain 2
chr10_+_103203552 0.57 ENSMUST00000179636.3
ENSMUST00000217905.2
ENSMUST00000074204.12
solute carrier family 6 (neurotransmitter transporter), member 15
chr5_-_38649291 0.56 ENSMUST00000129099.8
solute carrier family 2 (facilitated glucose transporter), member 9
chr7_-_80055168 0.56 ENSMUST00000107362.10
ENSMUST00000135306.3
furin (paired basic amino acid cleaving enzyme)
chr12_-_84664001 0.55 ENSMUST00000221070.2
ENSMUST00000021666.6
ENSMUST00000223107.2
ATP-binding cassette, sub-family D (ALD), member 4
chr18_-_73887528 0.55 ENSMUST00000041138.3
elaC ribonuclease Z 1
chr17_+_34866090 0.54 ENSMUST00000015605.15
activating transcription factor 6 beta
chr12_-_99529767 0.53 ENSMUST00000176928.3
ENSMUST00000223484.2
forkhead box N3
chr15_+_99192968 0.53 ENSMUST00000128352.8
ENSMUST00000145482.8
pre-mRNA processing factor 40B
chr6_+_134617903 0.50 ENSMUST00000062755.10
BLOC-1 related complex subunit 5
chrX_-_158921370 0.49 ENSMUST00000033662.9
pyruvate dehydrogenase E1 alpha 1
chr11_+_109434519 0.46 ENSMUST00000106696.2
arylsulfatase G
chr8_+_46463633 0.45 ENSMUST00000110381.9
Lrp2 binding protein
chr3_-_96104886 0.45 ENSMUST00000016087.4
bolA-like 1 (E. coli)
chr10_+_116013256 0.44 ENSMUST00000155606.8
ENSMUST00000128399.2
protein tyrosine phosphatase, receptor type, R
chr10_+_23770586 0.44 ENSMUST00000041416.8
vanin 1
chr9_-_82856321 0.44 ENSMUST00000189985.2
pleckstrin homology domain interacting protein
chr1_-_14380032 0.44 ENSMUST00000187790.2
EYA transcriptional coactivator and phosphatase 1
chr3_-_95778679 0.41 ENSMUST00000142437.2
ENSMUST00000067298.5
mitochondrial ribosomal protein S21
chr11_-_99979052 0.41 ENSMUST00000107419.2
keratin 32
chr2_+_83554770 0.41 ENSMUST00000141725.3
integrin alpha V
chr8_-_117809188 0.40 ENSMUST00000109093.9
ENSMUST00000098375.6
polycystic kidney disease 1 like 2
chr1_+_88234454 0.40 ENSMUST00000040210.14
transient receptor potential cation channel, subfamily M, member 8
chr10_+_116013122 0.39 ENSMUST00000148731.8
protein tyrosine phosphatase, receptor type, R
chr6_+_30610973 0.38 ENSMUST00000062758.11
carboxypeptidase A5
chr17_-_8366536 0.38 ENSMUST00000231927.2
ribonuclease T2A
chr9_+_54446268 0.37 ENSMUST00000060242.12
SH2 domain containing 7
chr9_+_72714156 0.37 ENSMUST00000055535.9
protogenin
chrX_-_125723491 0.37 ENSMUST00000081074.5
RIKEN cDNA 4932411N23 gene
chr19_+_44481901 0.37 ENSMUST00000041163.5
wingless-type MMTV integration site family, member 8B
chr19_-_11833365 0.37 ENSMUST00000079875.4
olfactory receptor 1418
chr2_+_87854404 0.36 ENSMUST00000217006.2
olfactory receptor 1161
chrX_+_118836893 0.35 ENSMUST00000040961.3
ENSMUST00000113366.2
poly(A) binding protein, cytoplasmic 5
chr6_+_30611028 0.35 ENSMUST00000115138.8
carboxypeptidase A5
chr1_+_177557380 0.35 ENSMUST00000016106.6
RIKEN cDNA 1700016C15 gene
chr7_-_29605949 0.35 ENSMUST00000159920.2
ENSMUST00000162592.8
zinc finger protein 27
chr1_+_178626003 0.34 ENSMUST00000160789.2
kinesin family member 26B
chr2_+_87260619 0.33 ENSMUST00000215909.2
olfactory receptor 1124
chr2_-_151510453 0.33 ENSMUST00000180195.8
ENSMUST00000096439.4
RAD21-like (S. pombe)
chr12_+_87490666 0.32 ENSMUST00000161023.8
ENSMUST00000160488.8
ENSMUST00000077462.8
ENSMUST00000160880.2
SRA stem-loop interacting RNA binding protein
chr10_+_34265969 0.32 ENSMUST00000105511.2
collagen, type X, alpha 1
chr6_+_123755838 0.31 ENSMUST00000075095.7
ENSMUST00000233759.2
ENSMUST00000232985.2
vomeronasal 2, receptor 24
chr4_+_118818775 0.31 ENSMUST00000058651.5
L-amino acid oxidase 1
chr8_-_85389470 0.29 ENSMUST00000060427.6
immediate early response 2
chr9_-_99302205 0.28 ENSMUST00000123771.2
muscle and microspikes RAS
chr2_-_88909981 0.28 ENSMUST00000213724.2
olfactory receptor 1219
chr6_-_129077867 0.28 ENSMUST00000032258.8
C-type lectin domain family 2, member e
chr13_+_38388904 0.28 ENSMUST00000091641.13
ENSMUST00000178564.2
small nuclear ribonucleoprotein 48 (U11/U12)
chr1_-_160405464 0.28 ENSMUST00000238289.2
G protein-coupled receptor 52
chr2_+_89757653 0.28 ENSMUST00000213720.3
ENSMUST00000102609.3
olfactory receptor 1258
chr3_-_30194559 0.27 ENSMUST00000108271.10
MDS1 and EVI1 complex locus
chrM_+_7779 0.27 ENSMUST00000082408.1
mitochondrially encoded ATP synthase 6
chr5_-_121665249 0.27 ENSMUST00000152270.8
MAP kinase-activated protein kinase 5
chr6_-_122443494 0.25 ENSMUST00000204731.2
ribosomal modification protein rimK-like family member B
chr14_-_50521663 0.25 ENSMUST00000213701.2
olfactory receptor 732
chr11_-_87783073 0.25 ENSMUST00000213672.2
ENSMUST00000213928.2
olfactory receptor 462
chrX_+_158242121 0.25 ENSMUST00000112470.3
ENSMUST00000043151.12
ENSMUST00000156172.3
MAP7 domain containing 2
chr8_-_22396428 0.25 ENSMUST00000051965.5
defensin beta 11
chr17_+_37977879 0.25 ENSMUST00000215811.2
olfactory receptor 118
chr9_-_40015750 0.25 ENSMUST00000213858.2
olfactory receptor 984
chr1_+_65321215 0.23 ENSMUST00000140190.8
parathyroid hormone 2 receptor
chr7_+_17979272 0.23 ENSMUST00000066780.5
MHC I like leukocyte 1
chr4_+_88768324 0.23 ENSMUST00000094972.2
interferon alpha 1
chr14_-_20443676 0.22 ENSMUST00000061444.5
mitochondrial ribosomal protein S16
chrY_+_55729767 0.22 ENSMUST00000177834.2
predicted gene, 21858
chr2_-_89678487 0.22 ENSMUST00000214428.3
olfactory receptor 48
chr10_-_108535970 0.21 ENSMUST00000218023.2
predicted gene 5136
chr7_-_103191732 0.21 ENSMUST00000215663.2
olfactory receptor 612
chr1_-_63153675 0.21 ENSMUST00000097718.9
INO80 complex subunit D
chr3_-_96359622 0.21 ENSMUST00000093126.11
ENSMUST00000098841.4
cDNA sequence BC107364
chr4_+_101843823 0.21 ENSMUST00000106914.8
predicted gene 12789
chr4_+_148985584 0.20 ENSMUST00000147270.2
castor zinc finger 1
chrY_-_35875442 0.20 ENSMUST00000180332.2
predicted gene, 20896
chrY_+_84109980 0.20 ENSMUST00000177775.2
predicted gene, 21095
chr5_-_66672158 0.20 ENSMUST00000161879.8
ENSMUST00000159357.8
amyloid beta (A4) precursor protein-binding, family B, member 2
chr8_-_65440483 0.19 ENSMUST00000210982.2
tripartite motif-containing 75
chr1_-_134477400 0.18 ENSMUST00000172898.2
MGAT4 family, member E
chr8_-_65440298 0.18 ENSMUST00000095295.3
tripartite motif-containing 75
chrY_+_55211732 0.18 ENSMUST00000180249.2
predicted gene, 20931
chr10_+_116881246 0.18 ENSMUST00000073834.5
leucine rich repeat containing 10
chr7_-_103394150 0.17 ENSMUST00000213906.2
olfactory receptor 629
chr2_+_83554868 0.17 ENSMUST00000111740.9
integrin alpha V
chrY_+_65387652 0.16 ENSMUST00000178198.2
predicted gene, 20736
chr4_+_109092829 0.16 ENSMUST00000030285.8
calreticulin 4
chrY_+_79332266 0.16 ENSMUST00000178063.2
predicted gene, 20916
chr10_+_129403524 0.16 ENSMUST00000204820.3
olfactory receptor 794
chr2_+_83554741 0.16 ENSMUST00000028499.11
integrin alpha V
chr3_-_144555062 0.15 ENSMUST00000159989.2
chloride channel accessory 3B
chrM_+_7758 0.15 ENSMUST00000082407.1
mitochondrially encoded ATP synthase 8
chr2_-_165210622 0.15 ENSMUST00000141140.2
ENSMUST00000103085.8
zinc finger protein 663
chr19_-_12313274 0.15 ENSMUST00000208398.3
olfactory receptor 1438, pseudogene 1
chr3_-_33136153 0.15 ENSMUST00000108225.10
peroxisomal biogenesis factor 5-like
chrY_+_52778041 0.14 ENSMUST00000178673.2
predicted gene, 21258
chr8_+_22329942 0.14 ENSMUST00000006745.4
defensin beta 2
chr6_-_69920632 0.13 ENSMUST00000198880.5
ENSMUST00000103371.3
immunoglobulin kappa chain variable 12-38
chr11_+_73489420 0.13 ENSMUST00000214228.2
olfactory receptor 384
chr2_-_73410632 0.13 ENSMUST00000028515.4
cholinergic receptor, nicotinic, alpha polypeptide 1 (muscle)
chr1_+_58841808 0.12 ENSMUST00000190213.2
caspase 8
chr10_-_41570483 0.12 ENSMUST00000190522.2
coiled-coil domain containing 162
chr19_-_18978463 0.12 ENSMUST00000040153.15
ENSMUST00000112828.8
RAR-related orphan receptor beta
chr11_+_16207705 0.12 ENSMUST00000109645.9
ENSMUST00000109647.3
V-set and transmembrane domain containing 2A
chr4_+_145397238 0.11 ENSMUST00000105738.9
zinc finger protein 980
chr4_+_147056433 0.11 ENSMUST00000146688.3
zinc finger protein 989
chr2_-_111779785 0.10 ENSMUST00000099604.6
olfactory receptor 1307
chr16_-_69660606 0.10 ENSMUST00000076500.14
spermatogenesis associated glutamate (E)-rich protein 2
chr2_-_111820618 0.10 ENSMUST00000216948.2
ENSMUST00000214935.2
ENSMUST00000217452.2
ENSMUST00000215045.2
olfactory receptor 1309
chr16_-_19341016 0.09 ENSMUST00000214315.2
olfactory receptor 167
chr7_+_134870237 0.09 ENSMUST00000210697.2
ENSMUST00000097983.5
neuropeptide S
chr6_+_24733239 0.07 ENSMUST00000031690.6
hyaluronoglucosaminidase 6
chr8_+_40807344 0.07 ENSMUST00000136835.2
mitochondrial calcium uptake family, member 3
chr2_+_151336095 0.07 ENSMUST00000089140.13
NSFL1 (p97) cofactor (p47)
chr2_-_86257093 0.07 ENSMUST00000217481.2
olfactory receptor 1062
chr11_-_116572116 0.07 ENSMUST00000144398.2
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
chr2_+_37101586 0.05 ENSMUST00000214897.2
olfactory receptor 366
chrY_-_35085749 0.05 ENSMUST00000180170.2
predicted gene, 20855
chr5_-_23889607 0.05 ENSMUST00000197985.5
serine/arginine-rich protein specific kinase 2
chr7_-_11414074 0.05 ENSMUST00000227010.2
ENSMUST00000209638.3
vomeronasal 1 receptor 72
chr2_-_88581690 0.04 ENSMUST00000215179.3
ENSMUST00000215529.3
olfactory receptor 1198
chr14_+_69585036 0.04 ENSMUST00000064831.6
ectonucleoside triphosphate diphosphohydrolase 4
chr2_-_89779008 0.03 ENSMUST00000214846.2
olfactory receptor 1259
chr14_+_47535717 0.03 ENSMUST00000166743.9
mitogen-activated protein kinase 1 interacting protein 1-like
chr7_+_26456567 0.03 ENSMUST00000077855.8
cytochrome P450, family 2, subfamily b, polypeptide 19
chr1_-_126758520 0.03 ENSMUST00000162646.8
NCK-associated protein 5
chr4_+_115099237 0.03 ENSMUST00000118278.2
cytochrome P450, family 4, subfamily a, polypeptide 29
chr11_+_49045204 0.02 ENSMUST00000216273.2
olfactory receptor 1394
chr1_-_186947618 0.02 ENSMUST00000110945.4
ENSMUST00000183931.8
ENSMUST00000027908.13
spermatogenesis associated 17
chr5_-_103777145 0.01 ENSMUST00000031263.2
solute carrier family 10 (sodium/bile acid cotransporter family), member 6
chr15_+_57775595 0.01 ENSMUST00000022992.13
TBC1 domain family, member 31
chr19_-_13828056 0.01 ENSMUST00000208493.3
olfactory receptor 1501
chr12_+_31440842 0.01 ENSMUST00000167432.8
solute carrier family 26, member 3
chr15_-_101422054 0.01 ENSMUST00000230067.3
predicted gene, 49425
chr7_-_84661476 0.00 ENSMUST00000124773.3
ENSMUST00000233725.2
ENSMUST00000233739.2
ENSMUST00000232837.2
vomeronasal 2, receptor 66
chr16_-_58898368 0.00 ENSMUST00000216495.3
olfactory receptor 190

Network of associatons between targets according to the STRING database.

First level regulatory network of Hoxd8

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 5.3 GO:1901509 regulation of endothelial tube morphogenesis(GO:1901509)
0.5 5.8 GO:0052697 flavonoid glucuronidation(GO:0052696) xenobiotic glucuronidation(GO:0052697)
0.4 1.3 GO:1904211 membrane protein proteolysis involved in retrograde protein transport, ER to cytosol(GO:1904211)
0.4 1.7 GO:0046351 disaccharide biosynthetic process(GO:0046351)
0.4 8.5 GO:0042448 progesterone metabolic process(GO:0042448)
0.3 0.9 GO:0001966 thigmotaxis(GO:0001966)
0.3 1.2 GO:0090118 regulation of phosphatidylcholine catabolic process(GO:0010899) receptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport(GO:0090118) positive regulation of lysosomal protein catabolic process(GO:1905167)
0.2 4.7 GO:0071257 cellular response to electrical stimulus(GO:0071257)
0.2 0.7 GO:2000536 negative regulation of entry of bacterium into host cell(GO:2000536)
0.2 0.9 GO:0035262 gonad morphogenesis(GO:0035262)
0.2 2.4 GO:0072615 interleukin-17 secretion(GO:0072615)
0.2 3.1 GO:0015747 urate transport(GO:0015747)
0.2 6.6 GO:0019373 epoxygenase P450 pathway(GO:0019373)
0.2 0.8 GO:0036058 filtration diaphragm assembly(GO:0036058) slit diaphragm assembly(GO:0036060)
0.1 0.6 GO:0090472 dibasic protein processing(GO:0090472)
0.1 0.8 GO:0038128 ERBB2 signaling pathway(GO:0038128)
0.1 0.7 GO:1903903 regulation of establishment of T cell polarity(GO:1903903)
0.1 0.5 GO:0009235 cobalamin metabolic process(GO:0009235)
0.1 0.5 GO:0042780 tRNA 3'-end processing(GO:0042780)
0.1 1.2 GO:1990440 positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress(GO:1990440)
0.1 0.3 GO:0000957 mitochondrial RNA catabolic process(GO:0000957) regulation of mitochondrial RNA catabolic process(GO:0000960)
0.1 0.8 GO:0009162 deoxyribonucleoside monophosphate metabolic process(GO:0009162)
0.1 0.6 GO:0010890 positive regulation of sequestering of triglyceride(GO:0010890)
0.1 0.6 GO:0015820 branched-chain amino acid transport(GO:0015803) leucine transport(GO:0015820)
0.1 0.2 GO:0060220 camera-type eye photoreceptor cell fate commitment(GO:0060220)
0.1 1.7 GO:0044406 adhesion of symbiont to host(GO:0044406)
0.1 0.5 GO:0061732 mitochondrial acetyl-CoA biosynthetic process from pyruvate(GO:0061732)
0.1 1.1 GO:2000780 negative regulation of double-strand break repair(GO:2000780)
0.0 0.3 GO:0072092 ureteric bud invasion(GO:0072092)
0.0 0.7 GO:0031468 nuclear envelope reassembly(GO:0031468)
0.0 0.3 GO:0097240 meiotic telomere tethering at nuclear periphery(GO:0044821) meiotic attachment of telomere to nuclear envelope(GO:0070197) chromosome attachment to the nuclear envelope(GO:0097240)
0.0 0.4 GO:0072513 positive regulation of secondary heart field cardioblast proliferation(GO:0072513)
0.0 0.4 GO:0050955 thermoception(GO:0050955)
0.0 1.0 GO:0007614 short-term memory(GO:0007614)
0.0 0.6 GO:0046415 urate metabolic process(GO:0046415)
0.0 1.9 GO:0003333 amino acid transmembrane transport(GO:0003333)
0.0 0.4 GO:0090336 positive regulation of brown fat cell differentiation(GO:0090336)
0.0 0.3 GO:0090400 stress-induced premature senescence(GO:0090400)
0.0 2.0 GO:0046513 ceramide biosynthetic process(GO:0046513)
0.0 0.6 GO:0033539 fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
0.0 0.9 GO:0006825 copper ion transport(GO:0006825)
0.0 3.1 GO:0006818 hydrogen transport(GO:0006818)
0.0 0.4 GO:2000400 positive regulation of T cell differentiation in thymus(GO:0033089) positive regulation of thymocyte aggregation(GO:2000400)
0.0 0.4 GO:0043568 positive regulation of insulin-like growth factor receptor signaling pathway(GO:0043568)
0.0 0.6 GO:0001833 inner cell mass cell proliferation(GO:0001833)
0.0 0.5 GO:0097094 craniofacial suture morphogenesis(GO:0097094)
0.0 0.1 GO:0016560 protein import into peroxisome matrix, docking(GO:0016560)
0.0 0.1 GO:0036462 TRAIL-activated apoptotic signaling pathway(GO:0036462)
0.0 0.1 GO:0010841 positive regulation of circadian sleep/wake cycle, wakefulness(GO:0010841)
0.0 4.6 GO:0010466 negative regulation of peptidase activity(GO:0010466)
0.0 0.1 GO:0097503 sialylation(GO:0097503)
0.0 0.8 GO:0051438 regulation of ubiquitin-protein transferase activity(GO:0051438)
0.0 0.1 GO:0035063 nuclear speck organization(GO:0035063)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.2 GO:1990666 PCSK9-LDLR complex(GO:1990666)
0.2 1.3 GO:0071556 integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458) integral component of lumenal side of endoplasmic reticulum membrane(GO:0071556) lumenal side of endoplasmic reticulum membrane(GO:0098553)
0.2 0.7 GO:1990730 VCP-NSFL1C complex(GO:1990730)
0.2 0.7 GO:0034686 integrin alphav-beta3 complex(GO:0034683) integrin alphav-beta8 complex(GO:0034686)
0.2 0.6 GO:0045251 mitochondrial electron transfer flavoprotein complex(GO:0017133) electron transfer flavoprotein complex(GO:0045251)
0.1 1.7 GO:0020005 symbiont-containing vacuole membrane(GO:0020005)
0.1 4.5 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.1 4.7 GO:0045334 clathrin-coated endocytic vesicle(GO:0045334)
0.1 0.8 GO:0031462 Cul2-RING ubiquitin ligase complex(GO:0031462)
0.1 0.3 GO:0032156 septin cytoskeleton(GO:0032156)
0.1 0.5 GO:0045254 pyruvate dehydrogenase complex(GO:0045254)
0.1 0.9 GO:0030670 phagocytic vesicle membrane(GO:0030670)
0.1 0.5 GO:0098574 cytoplasmic side of lysosomal membrane(GO:0098574)
0.1 0.3 GO:0034991 nuclear meiotic cohesin complex(GO:0034991)
0.0 0.7 GO:0031254 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.0 0.6 GO:0012510 trans-Golgi network transport vesicle membrane(GO:0012510)
0.0 6.1 GO:0031227 intrinsic component of endoplasmic reticulum membrane(GO:0031227)
0.0 0.1 GO:0030690 Noc1p-Noc2p complex(GO:0030690)
0.0 0.4 GO:0045263 proton-transporting ATP synthase complex, coupling factor F(o)(GO:0045263)
0.0 0.5 GO:0071004 U2-type prespliceosome(GO:0071004)
0.0 1.1 GO:0035861 site of double-strand break(GO:0035861)
0.0 0.2 GO:0070552 BRISC complex(GO:0070552)
0.0 1.8 GO:0030672 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.0 0.6 GO:0000314 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.0 0.1 GO:0017071 intracellular cyclic nucleotide activated cation channel complex(GO:0017071)
0.0 1.2 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 0.9 GO:0016235 aggresome(GO:0016235)
0.0 0.0 GO:0097636 intrinsic component of autophagosome membrane(GO:0097636) integral component of autophagosome membrane(GO:0097637)
0.0 0.3 GO:0005689 U12-type spliceosomal complex(GO:0005689)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.7 GO:0019002 GMP binding(GO:0019002)
0.5 2.1 GO:0042284 sphingolipid delta-4 desaturase activity(GO:0042284)
0.5 3.5 GO:0047035 testosterone dehydrogenase (NAD+) activity(GO:0047035)
0.4 2.7 GO:0004022 alcohol dehydrogenase (NAD) activity(GO:0004022)
0.4 8.5 GO:0016832 aldehyde-lyase activity(GO:0016832)
0.4 2.4 GO:0008142 oxysterol binding(GO:0008142)
0.3 3.1 GO:0015562 efflux transmembrane transporter activity(GO:0015562)
0.2 5.3 GO:0044548 S100 protein binding(GO:0044548)
0.2 8.7 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.2 6.6 GO:0008392 arachidonic acid epoxygenase activity(GO:0008392)
0.2 1.2 GO:0030229 very-low-density lipoprotein particle receptor activity(GO:0030229)
0.1 1.3 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.1 1.0 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.1 1.7 GO:0050308 sugar-phosphatase activity(GO:0050308)
0.1 0.3 GO:0001716 L-amino-acid oxidase activity(GO:0001716)
0.1 0.5 GO:0034604 pyruvate dehydrogenase activity(GO:0004738) pyruvate dehydrogenase [NAD(P)+] activity(GO:0034603) pyruvate dehydrogenase (NAD+) activity(GO:0034604)
0.1 0.3 GO:0001588 dopamine neurotransmitter receptor activity, coupled via Gs(GO:0001588)
0.1 0.9 GO:0004322 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.1 0.7 GO:0019960 C-X3-C chemokine binding(GO:0019960) extracellular matrix protein binding(GO:1990430)
0.1 0.6 GO:0043199 sulfate binding(GO:0043199)
0.1 10.0 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.1 0.3 GO:0072591 citrate-L-glutamate ligase activity(GO:0072591)
0.1 1.2 GO:0035497 cAMP response element binding(GO:0035497)
0.1 0.6 GO:0015193 L-proline transmembrane transporter activity(GO:0015193)
0.1 0.4 GO:0034235 GPI anchor binding(GO:0034235)
0.0 1.1 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.0 0.6 GO:1901702 urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.0 0.2 GO:0004991 parathyroid hormone receptor activity(GO:0004991)
0.0 0.4 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.0 0.1 GO:0097199 cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097199)
0.0 0.8 GO:0016799 hydrolase activity, hydrolyzing N-glycosyl compounds(GO:0016799)
0.0 0.5 GO:0008484 sulfuric ester hydrolase activity(GO:0008484)
0.0 0.1 GO:0005052 peroxisome matrix targeting signal-1 binding(GO:0005052)
0.0 4.7 GO:0003774 motor activity(GO:0003774)
0.0 0.7 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 0.1 GO:0008502 melatonin receptor activity(GO:0008502)
0.0 0.8 GO:0017147 Wnt-protein binding(GO:0017147)
0.0 0.5 GO:0016891 endoribonuclease activity, producing 5'-phosphomonoesters(GO:0016891)
0.0 0.3 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.0 0.9 GO:0005044 scavenger receptor activity(GO:0005044)
0.0 1.9 GO:0015171 amino acid transmembrane transporter activity(GO:0015171)
0.0 0.4 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.0 0.2 GO:0005132 type I interferon receptor binding(GO:0005132)
0.0 0.7 GO:0035255 ionotropic glutamate receptor binding(GO:0035255)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 4.7 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.0 4.6 PID FGF PATHWAY FGF signaling pathway
0.0 0.7 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0 2.4 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.0 1.0 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.0 0.7 SIG PIP3 SIGNALING IN B LYMPHOCYTES Genes related to PIP3 signaling in B lymphocytes
0.0 0.8 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.4 4.2 REACTOME XENOBIOTICS Genes involved in Xenobiotics
0.6 8.5 REACTOME ANDROGEN BIOSYNTHESIS Genes involved in Androgen biosynthesis
0.3 3.1 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.3 5.3 REACTOME FGFR4 LIGAND BINDING AND ACTIVATION Genes involved in FGFR4 ligand binding and activation
0.2 4.7 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.1 3.1 REACTOME PYRUVATE METABOLISM AND CITRIC ACID TCA CYCLE Genes involved in Pyruvate metabolism and Citric Acid (TCA) cycle
0.1 0.5 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.0 1.2 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.0 0.6 REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.0 2.4 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.0 0.6 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.0 1.7 REACTOME GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.0 0.7 REACTOME PECAM1 INTERACTIONS Genes involved in PECAM1 interactions
0.0 2.5 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 0.9 REACTOME METAL ION SLC TRANSPORTERS Genes involved in Metal ion SLC transporters
0.0 0.2 REACTOME REGULATION OF IFNA SIGNALING Genes involved in Regulation of IFNA signaling