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GSE58827: Dynamics of the Mouse Liver

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Results for Hoxd9

Z-value: 0.86

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Transcription factors associated with Hoxd9

Gene Symbol Gene ID Gene Info
Hoxd9
ENSMUSG00000043342.10 homeobox D9

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Hoxd9mm39_v1_chr2_+_74528071_745280970.289.9e-02Click!

Activity profile of Hoxd9 motif

Sorted Z-values of Hoxd9 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr6_-_41291634 5.89 ENSMUST00000064324.12
Try5
trypsin 5
chr14_+_66043281 4.02 ENSMUST00000022612.10
Pbk
PDZ binding kinase
chr15_+_6673167 3.91 ENSMUST00000163073.2
Fyb
FYN binding protein
chr3_-_115923098 3.86 ENSMUST00000196449.5
Vcam1
vascular cell adhesion molecule 1
chr3_-_14843512 2.99 ENSMUST00000094365.11
Car1
carbonic anhydrase 1
chrX_-_142610371 2.81 ENSMUST00000087316.6
Capn6
calpain 6
chr15_-_98832403 2.78 ENSMUST00000077577.8
Tuba1b
tubulin, alpha 1B
chr6_-_142418801 2.58 ENSMUST00000032371.8
Gys2
glycogen synthase 2
chr9_-_64080161 2.07 ENSMUST00000176299.8
ENSMUST00000130127.8
ENSMUST00000176794.8
ENSMUST00000177045.8
Zwilch
zwilch kinetochore protein
chr3_+_60503051 1.82 ENSMUST00000192757.6
ENSMUST00000193518.6
ENSMUST00000195817.3
Mbnl1
muscleblind like splicing factor 1
chrX_-_165992311 1.81 ENSMUST00000112172.4
Tmsb4x
thymosin, beta 4, X chromosome
chr16_-_75706161 1.77 ENSMUST00000114239.9
Samsn1
SAM domain, SH3 domain and nuclear localization signals, 1
chr10_-_35587888 1.75 ENSMUST00000080898.4
Amd2
S-adenosylmethionine decarboxylase 2
chr7_+_89814713 1.72 ENSMUST00000207084.2
Picalm
phosphatidylinositol binding clathrin assembly protein
chrX_-_165992145 1.67 ENSMUST00000112176.8
Tmsb4x
thymosin, beta 4, X chromosome
chr5_+_117378510 1.64 ENSMUST00000111975.3
Taok3
TAO kinase 3
chr12_+_117807224 1.64 ENSMUST00000021592.16
Cdca7l
cell division cycle associated 7 like
chrX_-_48886577 1.63 ENSMUST00000033442.14
ENSMUST00000114891.2
Igsf1
immunoglobulin superfamily, member 1
chr1_-_23948764 1.55 ENSMUST00000129254.8
Smap1
small ArfGAP 1
chr2_-_84255602 1.39 ENSMUST00000074262.9
Calcrl
calcitonin receptor-like
chr6_+_38918327 1.37 ENSMUST00000160963.2
Tbxas1
thromboxane A synthase 1, platelet
chr14_+_66378382 1.35 ENSMUST00000022620.11
Chrna2
cholinergic receptor, nicotinic, alpha polypeptide 2 (neuronal)
chr2_-_151586063 1.32 ENSMUST00000109869.2
Psmf1
proteasome (prosome, macropain) inhibitor subunit 1
chr17_-_78991691 1.28 ENSMUST00000145480.2
Strn
striatin, calmodulin binding protein
chr1_-_138103021 1.23 ENSMUST00000182755.8
ENSMUST00000193650.2
ENSMUST00000182283.8
Ptprc
protein tyrosine phosphatase, receptor type, C
chrX_-_133652140 1.22 ENSMUST00000052431.12
Armcx6
armadillo repeat containing, X-linked 6
chr19_-_56536646 1.22 ENSMUST00000182276.2
Dclre1a
DNA cross-link repair 1A
chr2_+_11176891 1.19 ENSMUST00000028118.9
Prkcq
protein kinase C, theta
chr9_-_39515420 1.17 ENSMUST00000042485.11
ENSMUST00000141370.8
AW551984
expressed sequence AW551984
chr1_+_88139678 1.14 ENSMUST00000073049.7
Ugt1a1
UDP glucuronosyltransferase 1 family, polypeptide A1
chr10_+_89580849 1.12 ENSMUST00000020112.7
Uhrf1bp1l
UHRF1 (ICBP90) binding protein 1-like
chr6_-_87510200 1.09 ENSMUST00000113637.9
ENSMUST00000071024.7
Arhgap25
Rho GTPase activating protein 25
chr3_-_129834788 1.09 ENSMUST00000168644.3
Sec24b
Sec24 related gene family, member B (S. cerevisiae)
chr6_-_69800923 1.09 ENSMUST00000103368.3
Igkv5-43
immunoglobulin kappa chain variable 5-43
chr16_+_29884153 1.06 ENSMUST00000023171.8
Hes1
hes family bHLH transcription factor 1
chr1_-_97689263 1.06 ENSMUST00000171129.8
Ppip5k2
diphosphoinositol pentakisphosphate kinase 2
chr14_+_43951187 1.04 ENSMUST00000094051.6
Gm7324
predicted gene 7324
chrX_-_133652080 1.04 ENSMUST00000113194.8
Armcx6
armadillo repeat containing, X-linked 6
chr4_-_129472328 1.03 ENSMUST00000052835.9
Fam167b
family with sequence similarity 167, member B
chr19_+_56536685 1.03 ENSMUST00000071423.7
Nhlrc2
NHL repeat containing 2
chr5_-_18054702 1.01 ENSMUST00000165232.8
Cd36
CD36 molecule
chr10_-_93727003 0.98 ENSMUST00000180840.8
Metap2
methionine aminopeptidase 2
chr1_-_154975376 0.96 ENSMUST00000055322.6
Ier5
immediate early response 5
chr12_-_41536430 0.91 ENSMUST00000043884.6
Lrrn3
leucine rich repeat protein 3, neuronal
chr7_+_120450406 0.89 ENSMUST00000143322.9
ENSMUST00000106488.3
Eef2k
eukaryotic elongation factor-2 kinase
chr19_+_45433899 0.87 ENSMUST00000224478.2
Btrc
beta-transducin repeat containing protein
chr7_+_127661807 0.87 ENSMUST00000064821.14
Itgam
integrin alpha M
chr15_-_37459570 0.86 ENSMUST00000119730.8
ENSMUST00000120746.8
Ncald
neurocalcin delta
chrX_-_10083157 0.86 ENSMUST00000072393.9
ENSMUST00000044598.13
ENSMUST00000073392.11
ENSMUST00000115533.8
ENSMUST00000115532.2
Rpgr
retinitis pigmentosa GTPase regulator
chr1_-_138102972 0.85 ENSMUST00000195533.6
ENSMUST00000183301.8
Ptprc
protein tyrosine phosphatase, receptor type, C
chr6_-_68840015 0.84 ENSMUST00000103336.2
Igkv1-88
immunoglobulin kappa chain variable 1-88
chrX_-_133442596 0.81 ENSMUST00000054213.5
Timm8a1
translocase of inner mitochondrial membrane 8A1
chr11_+_23234644 0.80 ENSMUST00000150750.3
Xpo1
exportin 1
chrX_+_55493325 0.78 ENSMUST00000079663.7
Gm2174
predicted gene 2174
chr6_+_57679621 0.75 ENSMUST00000050077.15
Lancl2
LanC (bacterial lantibiotic synthetase component C)-like 2
chr19_-_56536443 0.74 ENSMUST00000182059.2
Dclre1a
DNA cross-link repair 1A
chr12_-_113589576 0.72 ENSMUST00000103446.2
Ighv5-6
immunoglobulin heavy variable 5-6
chr1_-_160079007 0.72 ENSMUST00000191909.6
Rabgap1l
RAB GTPase activating protein 1-like
chr5_+_145282064 0.71 ENSMUST00000079268.9
Cyp3a57
cytochrome P450, family 3, subfamily a, polypeptide 57
chr4_+_5724305 0.71 ENSMUST00000108380.2
Fam110b
family with sequence similarity 110, member B
chr12_-_118265103 0.69 ENSMUST00000222314.2
ENSMUST00000026367.11
Sp4
trans-acting transcription factor 4
chr6_+_70192384 0.68 ENSMUST00000103383.3
Igkv6-25
immunoglobulin kappa chain variable 6-25
chr3_+_5815863 0.65 ENSMUST00000192045.2
Gm8797
predicted pseudogene 8797
chr18_+_42669322 0.63 ENSMUST00000236418.2
Tcerg1
transcription elongation regulator 1 (CA150)
chr6_+_83985684 0.61 ENSMUST00000203803.3
ENSMUST00000204591.3
ENSMUST00000113823.8
ENSMUST00000153860.4
Dysf
dysferlin
chr1_-_128030148 0.58 ENSMUST00000086614.12
Zranb3
zinc finger, RAN-binding domain containing 3
chr11_+_67061908 0.57 ENSMUST00000018641.8
Myh2
myosin, heavy polypeptide 2, skeletal muscle, adult
chr1_+_180158035 0.56 ENSMUST00000070181.7
Itpkb
inositol 1,4,5-trisphosphate 3-kinase B
chr10_+_74872898 0.56 ENSMUST00000147802.9
ENSMUST00000020391.13
ENSMUST00000234625.2
Rab36
RAB36, member RAS oncogene family
chr6_+_48514518 0.56 ENSMUST00000040361.8
Atp6v0e2
ATPase, H+ transporting, lysosomal V0 subunit E2
chr18_+_31922173 0.53 ENSMUST00000025106.5
ENSMUST00000234146.2
Polr2d
polymerase (RNA) II (DNA directed) polypeptide D
chr10_-_129107354 0.50 ENSMUST00000204573.3
Olfr777
olfactory receptor 777
chr2_+_91357100 0.49 ENSMUST00000111338.10
Ckap5
cytoskeleton associated protein 5
chr3_+_32490525 0.49 ENSMUST00000108242.2
Pik3ca
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha
chr5_-_62923463 0.46 ENSMUST00000076623.8
ENSMUST00000159470.3
Arap2
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
chr5_-_100521343 0.45 ENSMUST00000182433.8
Sec31a
Sec31 homolog A (S. cerevisiae)
chr3_+_103078971 0.45 ENSMUST00000005830.15
Bcas2
breast carcinoma amplified sequence 2
chr8_-_41469332 0.45 ENSMUST00000131965.2
Mtus1
mitochondrial tumor suppressor 1
chr14_-_75991903 0.43 ENSMUST00000049168.9
Cog3
component of oligomeric golgi complex 3
chr16_-_22847760 0.41 ENSMUST00000039338.13
Kng2
kininogen 2
chr8_+_85583611 0.39 ENSMUST00000003906.13
ENSMUST00000109754.2
Farsa
phenylalanyl-tRNA synthetase, alpha subunit
chr11_+_31823096 0.38 ENSMUST00000155278.2
Cpeb4
cytoplasmic polyadenylation element binding protein 4
chr7_+_100435548 0.37 ENSMUST00000216021.2
Fam168a
family with sequence similarity 168, member A
chr16_-_22847829 0.37 ENSMUST00000100046.9
Kng2
kininogen 2
chr1_-_171854818 0.35 ENSMUST00000138714.2
ENSMUST00000027837.13
ENSMUST00000111264.8
Vangl2
VANGL planar cell polarity 2
chr5_-_104125192 0.34 ENSMUST00000120320.8
Hsd17b13
hydroxysteroid (17-beta) dehydrogenase 13
chr11_+_67061837 0.33 ENSMUST00000170159.8
Myh2
myosin, heavy polypeptide 2, skeletal muscle, adult
chr19_-_57185928 0.33 ENSMUST00000111544.8
Ablim1
actin-binding LIM protein 1
chr6_+_108771840 0.33 ENSMUST00000204483.2
Arl8b
ADP-ribosylation factor-like 8B
chr4_-_43710231 0.32 ENSMUST00000217544.2
ENSMUST00000107862.3
Olfr71
olfactory receptor 71
chr2_+_83642910 0.31 ENSMUST00000051454.4
Fam171b
family with sequence similarity 171, member B
chr19_-_57185988 0.30 ENSMUST00000099294.9
Ablim1
actin-binding LIM protein 1
chr14_-_123151162 0.30 ENSMUST00000160401.8
Ggact
gamma-glutamylamine cyclotransferase
chr2_-_85966272 0.30 ENSMUST00000216566.3
ENSMUST00000214364.2
Olfr1039
olfactory receptor 1039
chr6_-_98319684 0.28 ENSMUST00000164491.3
Mdfic2
MyoD family inhibitor domain containing 2
chr16_-_22847808 0.28 ENSMUST00000115349.9
Kng2
kininogen 2
chr10_-_18890281 0.28 ENSMUST00000146388.2
Tnfaip3
tumor necrosis factor, alpha-induced protein 3
chr7_-_84328553 0.26 ENSMUST00000069537.3
ENSMUST00000207865.2
ENSMUST00000178385.9
ENSMUST00000208782.2
Zfand6
zinc finger, AN1-type domain 6
chr17_+_75742881 0.26 ENSMUST00000164192.9
Rasgrp3
RAS, guanyl releasing protein 3
chr16_-_65359406 0.25 ENSMUST00000231259.2
Chmp2b
charged multivesicular body protein 2B
chr3_+_32490300 0.25 ENSMUST00000029201.14
Pik3ca
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha
chr3_+_113824181 0.25 ENSMUST00000123619.8
ENSMUST00000092155.12
Col11a1
collagen, type XI, alpha 1
chr5_-_69748126 0.25 ENSMUST00000166298.8
Gnpda2
glucosamine-6-phosphate deaminase 2
chr8_+_66838927 0.25 ENSMUST00000039540.12
ENSMUST00000110253.3
Marchf1
membrane associated ring-CH-type finger 1
chr1_-_140111138 0.24 ENSMUST00000111976.9
ENSMUST00000066859.13
Cfh
complement component factor h
chrX_+_41241049 0.24 ENSMUST00000128799.3
Stag2
stromal antigen 2
chr3_-_49711706 0.23 ENSMUST00000191794.2
Pcdh18
protocadherin 18
chr2_-_45000389 0.23 ENSMUST00000201804.4
ENSMUST00000028229.13
ENSMUST00000202187.4
ENSMUST00000153561.6
ENSMUST00000201490.2
Zeb2
zinc finger E-box binding homeobox 2
chr2_-_37537224 0.23 ENSMUST00000028279.10
Strbp
spermatid perinuclear RNA binding protein
chr16_+_21644692 0.21 ENSMUST00000232240.2
Map3k13
mitogen-activated protein kinase kinase kinase 13
chr3_+_30656204 0.21 ENSMUST00000192715.6
Mynn
myoneurin
chr7_+_45271229 0.20 ENSMUST00000033100.5
Izumo1
izumo sperm-egg fusion 1
chr6_+_18848600 0.20 ENSMUST00000201141.3
Lsm8
LSM8 homolog, U6 small nuclear RNA associated
chr13_+_49697919 0.19 ENSMUST00000177948.2
ENSMUST00000021820.14
Aspn
asporin
chr3_+_67799510 0.18 ENSMUST00000063263.5
ENSMUST00000182006.4
Iqcj
Iqschfp
IQ motif containing J
Iqcj and Schip1 fusion protein
chr14_-_56137697 0.17 ENSMUST00000111325.5
Sdr39u1
short chain dehydrogenase/reductase family 39U, member 1
chr1_-_140111018 0.17 ENSMUST00000192880.6
ENSMUST00000111977.8
Cfh
complement component factor h
chr2_-_152422220 0.16 ENSMUST00000053180.4
Defb19
defensin beta 19
chr3_+_35808269 0.16 ENSMUST00000029257.15
Atp11b
ATPase, class VI, type 11B
chrX_+_113384008 0.15 ENSMUST00000113371.8
ENSMUST00000040504.12
Klhl4
kelch-like 4
chr3_-_49711765 0.14 ENSMUST00000035931.13
Pcdh18
protocadherin 18
chr2_-_76700830 0.14 ENSMUST00000138542.2
Ttn
titin
chr1_-_82746169 0.14 ENSMUST00000027331.3
Tm4sf20
transmembrane 4 L six family member 20
chr3_-_144525255 0.14 ENSMUST00000029929.12
Clca3a2
chloride channel accessory 3A2
chr6_+_149226891 0.13 ENSMUST00000189837.2
Resf1
retroelement silencing factor 1
chr19_+_34078333 0.13 ENSMUST00000025685.8
Lipm
lipase, family member M
chr5_-_69699932 0.12 ENSMUST00000202423.2
Yipf7
Yip1 domain family, member 7
chr5_-_21087023 0.12 ENSMUST00000118174.8
Phtf2
putative homeodomain transcription factor 2
chr9_-_60594742 0.10 ENSMUST00000114032.8
ENSMUST00000166168.8
ENSMUST00000132366.2
Lrrc49
leucine rich repeat containing 49
chr4_+_109092610 0.10 ENSMUST00000106628.8
Calr4
calreticulin 4
chr19_+_39980868 0.09 ENSMUST00000049178.3
Cyp2c37
cytochrome P450, family 2. subfamily c, polypeptide 37
chr3_-_75177378 0.09 ENSMUST00000039047.5
Serpini2
serine (or cysteine) peptidase inhibitor, clade I, member 2
chr9_-_18297277 0.09 ENSMUST00000166825.8
Naalad2
N-acetylated alpha-linked acidic dipeptidase 2
chr6_+_83985495 0.08 ENSMUST00000113821.8
Dysf
dysferlin
chr13_+_93441447 0.08 ENSMUST00000109497.8
ENSMUST00000109498.8
ENSMUST00000060490.11
ENSMUST00000109492.9
ENSMUST00000109496.8
ENSMUST00000109495.8
Homer1
homer scaffolding protein 1
chr10_+_40559249 0.08 ENSMUST00000058747.4
Mettl24
methyltransferase like 24
chr19_-_57185861 0.08 ENSMUST00000111550.8
Ablim1
actin-binding LIM protein 1
chr2_-_88534814 0.07 ENSMUST00000216928.2
ENSMUST00000216977.2
Olfr1196
olfactory receptor 1196
chr5_+_136982100 0.07 ENSMUST00000111094.8
ENSMUST00000111097.8
Fis1
fission, mitochondrial 1
chr2_-_115895202 0.06 ENSMUST00000110906.9
Meis2
Meis homeobox 2
chr10_+_129153986 0.06 ENSMUST00000215503.2
Olfr780
olfactory receptor 780
chr2_+_85648823 0.06 ENSMUST00000214416.2
Olfr1018
olfactory receptor 1018
chr7_+_107679062 0.05 ENSMUST00000213601.2
Olfr481
olfactory receptor 481
chr6_+_41095752 0.05 ENSMUST00000103269.3
Trbv12-2
T cell receptor beta, variable 12-2
chr4_+_109092459 0.04 ENSMUST00000106631.9
Calr4
calreticulin 4
chrM_+_11735 0.04 ENSMUST00000082418.1
mt-Nd5
mitochondrially encoded NADH dehydrogenase 5
chr2_-_87467879 0.03 ENSMUST00000216082.2
Olfr1132
olfactory receptor 1132
chr10_-_81102740 0.02 ENSMUST00000046114.5
Mrpl54
mitochondrial ribosomal protein L54
chr13_-_100453124 0.02 ENSMUST00000042220.3
Naip6
NLR family, apoptosis inhibitory protein 6
chr3_+_138058139 0.02 ENSMUST00000090166.5
Adh6b
alcohol dehydrogenase 6B (class V)
chr9_+_43222104 0.02 ENSMUST00000034511.7
Trim29
tripartite motif-containing 29
chr18_+_32200781 0.01 ENSMUST00000025243.5
ENSMUST00000212675.2
Iws1
IWS1, SUPT6 interacting protein
chr17_+_78815493 0.01 ENSMUST00000024880.11
ENSMUST00000232859.2
Vit
vitrin
chr8_-_62576140 0.00 ENSMUST00000034052.14
ENSMUST00000034054.9
Anxa10
annexin A10
chr2_+_88470886 0.00 ENSMUST00000217379.2
ENSMUST00000120598.3
Olfr1191-ps1
olfactory receptor 1191, pseudogene 1
chr10_+_23952398 0.00 ENSMUST00000051133.6
Taar8a
trace amine-associated receptor 8A

Network of associatons between targets according to the STRING database.

First level regulatory network of Hoxd9

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.8 GO:0006597 spermine biosynthetic process(GO:0006597)
0.5 2.1 GO:2000471 regulation of hematopoietic stem cell migration(GO:2000471) positive regulation of hematopoietic stem cell migration(GO:2000473)
0.4 1.1 GO:0018879 biphenyl metabolic process(GO:0018879)
0.4 1.1 GO:2000978 trochlear nerve development(GO:0021558) auditory receptor cell fate determination(GO:0042668) negative regulation of forebrain neuron differentiation(GO:2000978)
0.3 1.4 GO:0034285 response to sucrose(GO:0009744) response to disaccharide(GO:0034285)
0.3 3.9 GO:0060710 chorio-allantoic fusion(GO:0060710)
0.3 1.7 GO:1902962 regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902962) negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902963)
0.3 1.1 GO:1901301 regulation of cargo loading into COPII-coated vesicle(GO:1901301)
0.2 0.7 GO:0044028 DNA hypomethylation(GO:0044028) hypomethylation of CpG island(GO:0044029)
0.2 2.0 GO:0031848 protection from non-homologous end joining at telomere(GO:0031848)
0.2 1.0 GO:0070543 response to linoleic acid(GO:0070543)
0.2 3.5 GO:0051152 positive regulation of smooth muscle cell differentiation(GO:0051152)
0.2 0.7 GO:1901421 positive regulation of response to alcohol(GO:1901421)
0.2 0.5 GO:0031990 mRNA export from nucleus in response to heat stress(GO:0031990)
0.1 1.2 GO:2000318 positive regulation of T-helper 17 type immune response(GO:2000318)
0.1 0.6 GO:0048478 replication fork protection(GO:0048478)
0.1 0.3 GO:0060448 dichotomous subdivision of terminal units involved in lung branching(GO:0060448)
0.1 0.9 GO:0014004 microglia differentiation(GO:0014004) microglia development(GO:0014005)
0.1 1.0 GO:1900034 regulation of cellular response to heat(GO:1900034)
0.1 0.4 GO:1905051 regulation of base-excision repair(GO:1905051) positive regulation of base-excision repair(GO:1905053)
0.1 0.6 GO:0033030 negative regulation of neutrophil apoptotic process(GO:0033030)
0.1 0.3 GO:0034148 regulation of granuloma formation(GO:0002631) negative regulation of granuloma formation(GO:0002632) regulation of toll-like receptor 5 signaling pathway(GO:0034147) negative regulation of toll-like receptor 5 signaling pathway(GO:0034148) negative regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070429)
0.1 1.1 GO:0006020 inositol metabolic process(GO:0006020)
0.1 0.5 GO:0030951 establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951)
0.1 0.8 GO:0000056 ribosomal small subunit export from nucleus(GO:0000056)
0.1 0.4 GO:0006432 phenylalanyl-tRNA aminoacylation(GO:0006432)
0.1 1.4 GO:0030644 cellular chloride ion homeostasis(GO:0030644)
0.1 5.7 GO:0032873 negative regulation of stress-activated MAPK cascade(GO:0032873) negative regulation of stress-activated protein kinase signaling cascade(GO:0070303)
0.1 1.2 GO:0060923 cardiac muscle cell fate commitment(GO:0060923)
0.1 2.8 GO:0071353 cellular response to interleukin-4(GO:0071353)
0.1 1.0 GO:0018206 peptidyl-methionine modification(GO:0018206)
0.1 1.1 GO:0001778 plasma membrane repair(GO:0001778)
0.1 3.0 GO:0006730 one-carbon metabolic process(GO:0006730)
0.0 0.4 GO:0045919 positive regulation of cytolysis(GO:0045919)
0.0 0.2 GO:0070171 negative regulation of tooth mineralization(GO:0070171)
0.0 1.6 GO:2000369 regulation of clathrin-mediated endocytosis(GO:2000369)
0.0 1.8 GO:0050869 negative regulation of B cell activation(GO:0050869)
0.0 3.9 GO:0045576 mast cell activation(GO:0045576)
0.0 1.3 GO:0007274 neuromuscular synaptic transmission(GO:0007274)
0.0 1.8 GO:0006376 mRNA splice site selection(GO:0006376)
0.0 5.7 GO:0007586 digestion(GO:0007586)
0.0 0.2 GO:0035989 tendon development(GO:0035989)
0.0 0.1 GO:0043056 forward locomotion(GO:0043056)
0.0 0.4 GO:2000766 negative regulation of cytoplasmic translation(GO:2000766)
0.0 0.1 GO:1904578 response to thapsigargin(GO:1904578) cellular response to thapsigargin(GO:1904579)
0.0 2.6 GO:0005978 glycogen biosynthetic process(GO:0005978) glucan biosynthetic process(GO:0009250)
0.0 0.5 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.0 0.2 GO:0032876 negative regulation of DNA endoreduplication(GO:0032876)
0.0 1.3 GO:1901799 negative regulation of proteasomal protein catabolic process(GO:1901799)
0.0 0.8 GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
0.0 2.8 GO:0001578 microtubule bundle formation(GO:0001578)
0.0 0.9 GO:0061003 positive regulation of dendritic spine morphogenesis(GO:0061003)
0.0 0.7 GO:0035855 megakaryocyte development(GO:0035855)
0.0 1.1 GO:0030195 negative regulation of blood coagulation(GO:0030195) negative regulation of hemostasis(GO:1900047)
0.0 0.3 GO:1901673 regulation of mitotic spindle assembly(GO:1901673)
0.0 0.9 GO:0042073 intraciliary transport(GO:0042073)
0.0 0.6 GO:0015991 ATP hydrolysis coupled proton transport(GO:0015991)
0.0 2.1 GO:0007093 mitotic cell cycle checkpoint(GO:0007093)
0.0 0.2 GO:0007342 fusion of sperm to egg plasma membrane(GO:0007342)
0.0 0.3 GO:0032418 lysosome localization(GO:0032418)
0.0 0.2 GO:0006044 N-acetylglucosamine metabolic process(GO:0006044)
0.0 1.0 GO:0045454 cell redox homeostasis(GO:0045454)
0.0 0.4 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.0 0.4 GO:0010758 regulation of macrophage chemotaxis(GO:0010758)
0.0 0.4 GO:0006891 intra-Golgi vesicle-mediated transport(GO:0006891)
0.0 0.3 GO:0042219 cellular modified amino acid catabolic process(GO:0042219)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.1 GO:1990423 RZZ complex(GO:1990423)
0.2 0.7 GO:0005943 phosphatidylinositol 3-kinase complex, class IA(GO:0005943)
0.2 1.7 GO:0070381 endosome to plasma membrane transport vesicle(GO:0070381)
0.1 0.4 GO:0009328 phenylalanine-tRNA ligase complex(GO:0009328)
0.1 0.3 GO:0060187 cell pole(GO:0060187)
0.1 0.9 GO:0005826 actomyosin contractile ring(GO:0005826)
0.1 1.5 GO:0030127 COPII vesicle coat(GO:0030127)
0.1 1.1 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.1 3.9 GO:0002102 podosome(GO:0002102)
0.1 2.2 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.1 1.3 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.1 0.8 GO:0005642 annulate lamellae(GO:0005642)
0.0 2.8 GO:0005876 spindle microtubule(GO:0005876)
0.0 2.8 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.0 0.6 GO:0033179 proton-transporting V-type ATPase, V0 domain(GO:0033179)
0.0 0.4 GO:0017119 Golgi transport complex(GO:0017119)
0.0 3.3 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.0 0.5 GO:0005662 Prp19 complex(GO:0000974) DNA replication factor A complex(GO:0005662)
0.0 0.4 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.0 0.9 GO:0030131 clathrin adaptor complex(GO:0030131)
0.0 0.5 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.0 1.2 GO:0016235 aggresome(GO:0016235)
0.0 0.3 GO:0000815 ESCRT III complex(GO:0000815)
0.0 1.8 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 0.2 GO:0098643 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.0 0.5 GO:0035371 microtubule plus-end(GO:0035371)
0.0 3.6 GO:0001650 fibrillar center(GO:0001650)
0.0 0.6 GO:0043596 nuclear replication fork(GO:0043596)
0.0 0.8 GO:0032391 photoreceptor connecting cilium(GO:0032391)
0.0 0.2 GO:0005688 U6 snRNP(GO:0005688)
0.0 0.2 GO:0008385 IkappaB kinase complex(GO:0008385)
0.0 0.3 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.0 0.6 GO:0008305 integrin complex(GO:0008305)
0.0 1.7 GO:0016363 nuclear matrix(GO:0016363)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 2.6 GO:0004373 glycogen (starch) synthase activity(GO:0004373)
0.5 1.4 GO:0004948 calcitonin receptor activity(GO:0004948)
0.4 3.9 GO:0008131 primary amine oxidase activity(GO:0008131)
0.4 1.1 GO:0071820 N-box binding(GO:0071820)
0.3 3.0 GO:0004064 arylesterase activity(GO:0004064)
0.3 0.9 GO:0004686 elongation factor-2 kinase activity(GO:0004686)
0.3 1.8 GO:0019808 polyamine binding(GO:0019808)
0.2 2.0 GO:0035312 5'-3' exodeoxyribonuclease activity(GO:0035312)
0.2 1.0 GO:0070892 lipoteichoic acid receptor activity(GO:0070892)
0.2 1.3 GO:0001851 complement component C3b binding(GO:0001851)
0.2 1.6 GO:0034711 inhibin binding(GO:0034711)
0.2 1.1 GO:0052723 inositol hexakisphosphate kinase activity(GO:0000828) inositol hexakisphosphate 5-kinase activity(GO:0000832) inositol hexakisphosphate 1-kinase activity(GO:0052723) inositol hexakisphosphate 3-kinase activity(GO:0052724)
0.1 0.7 GO:0008390 testosterone 16-alpha-hydroxylase activity(GO:0008390)
0.1 1.8 GO:0001069 regulatory region RNA binding(GO:0001069)
0.1 1.7 GO:0032050 clathrin heavy chain binding(GO:0032050)
0.1 0.6 GO:0008440 inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440)
0.1 2.8 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.1 0.2 GO:0004342 glucosamine-6-phosphate deaminase activity(GO:0004342)
0.1 2.1 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
0.1 3.5 GO:0003785 actin monomer binding(GO:0003785)
0.1 1.3 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848) acetylcholine binding(GO:0042166)
0.1 0.4 GO:0004826 phenylalanine-tRNA ligase activity(GO:0004826)
0.1 0.8 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.1 1.3 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.1 0.7 GO:0052813 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol bisphosphate kinase activity(GO:0052813)
0.1 1.9 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.1 0.6 GO:0036310 annealing helicase activity(GO:0036310)
0.1 1.3 GO:0070628 proteasome binding(GO:0070628)
0.1 0.3 GO:0003839 gamma-glutamylcyclotransferase activity(GO:0003839)
0.0 1.2 GO:0004697 protein kinase C activity(GO:0004697)
0.0 0.7 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.0 0.3 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.0 0.7 GO:0001972 retinoic acid binding(GO:0001972)
0.0 0.4 GO:0000900 translation repressor activity, nucleic acid binding(GO:0000900)
0.0 1.2 GO:0043014 alpha-tubulin binding(GO:0043014)
0.0 2.6 GO:0045309 protein phosphorylated amino acid binding(GO:0045309)
0.0 1.4 GO:0016860 intramolecular oxidoreductase activity(GO:0016860)
0.0 2.5 GO:0003725 double-stranded RNA binding(GO:0003725)
0.0 4.8 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 0.5 GO:0051010 microtubule plus-end binding(GO:0051010)
0.0 0.6 GO:0070064 proline-rich region binding(GO:0070064)
0.0 0.2 GO:0086080 protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
0.0 0.6 GO:0046961 proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.0 1.0 GO:0004177 aminopeptidase activity(GO:0004177)
0.0 0.1 GO:0031433 telethonin binding(GO:0031433)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.6 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.1 2.8 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.1 0.6 ST PAC1 RECEPTOR PATHWAY PAC1 Receptor Pathway
0.1 7.0 PID TCR PATHWAY TCR signaling in naïve CD4+ T cells
0.1 0.9 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.0 1.6 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.0 0.8 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.0 1.8 PID AMB2 NEUTROPHILS PATHWAY amb2 Integrin signaling
0.0 2.0 PID ER NONGENOMIC PATHWAY Plasma membrane estrogen receptor signaling
0.0 1.1 PID FANCONI PATHWAY Fanconi anemia pathway
0.0 0.3 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway
0.0 0.5 PID AURORA A PATHWAY Aurora A signaling
0.0 0.5 PID ARF6 PATHWAY Arf6 signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.8 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.1 2.1 REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.1 3.9 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
0.1 1.1 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.1 1.3 REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.1 1.5 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.1 3.6 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.1 1.9 REACTOME TCR SIGNALING Genes involved in TCR signaling
0.0 0.9 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
0.0 0.9 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 0.8 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.0 0.4 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.0 1.4 REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.0 4.5 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.0 0.9 REACTOME PROLACTIN RECEPTOR SIGNALING Genes involved in Prolactin receptor signaling
0.0 2.6 REACTOME GLUCOSE METABOLISM Genes involved in Glucose metabolism
0.0 0.5 REACTOME VIRAL MESSENGER RNA SYNTHESIS Genes involved in Viral Messenger RNA Synthesis
0.0 2.8 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.0 1.7 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.0 1.1 REACTOME REGULATION OF BETA CELL DEVELOPMENT Genes involved in Regulation of beta-cell development
0.0 0.5 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.0 0.4 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation