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GSE58827: Dynamics of the Mouse Liver

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Results for Hsf1

Z-value: 0.63

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Transcription factors associated with Hsf1

Gene Symbol Gene ID Gene Info
Hsf1
ENSMUSG00000022556.12 heat shock factor 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Hsf1mm39_v1_chr15_+_76361604_763617740.464.3e-03Click!

Activity profile of Hsf1 motif

Sorted Z-values of Hsf1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr12_-_110662256 3.50 ENSMUST00000149189.2
Hsp90aa1
heat shock protein 90, alpha (cytosolic), class A member 1
chr11_+_87684299 2.92 ENSMUST00000020779.11
Mpo
myeloperoxidase
chr5_-_149559636 2.73 ENSMUST00000201452.4
Hsph1
heat shock 105kDa/110kDa protein 1
chr12_-_110662677 2.73 ENSMUST00000124156.8
Hsp90aa1
heat shock protein 90, alpha (cytosolic), class A member 1
chr12_-_110662723 2.70 ENSMUST00000021698.13
Hsp90aa1
heat shock protein 90, alpha (cytosolic), class A member 1
chr12_-_110662765 2.61 ENSMUST00000094361.11
Hsp90aa1
heat shock protein 90, alpha (cytosolic), class A member 1
chr5_-_149559667 2.47 ENSMUST00000074846.14
Hsph1
heat shock 105kDa/110kDa protein 1
chr17_+_48606948 2.25 ENSMUST00000233092.2
Treml2
triggering receptor expressed on myeloid cells-like 2
chr3_+_79498663 2.15 ENSMUST00000029382.13
Ppid
peptidylprolyl isomerase D (cyclophilin D)
chr17_+_48607405 2.14 ENSMUST00000170941.3
Treml2
triggering receptor expressed on myeloid cells-like 2
chr6_-_51446752 1.80 ENSMUST00000204188.3
ENSMUST00000203220.3
ENSMUST00000114459.8
ENSMUST00000090002.10
Hnrnpa2b1
heterogeneous nuclear ribonucleoprotein A2/B1
chr7_-_110462446 1.76 ENSMUST00000033050.5
Lyve1
lymphatic vessel endothelial hyaluronan receptor 1
chr5_-_149559792 1.76 ENSMUST00000202361.4
ENSMUST00000202089.4
ENSMUST00000200825.2
ENSMUST00000201559.4
Hsph1
heat shock 105kDa/110kDa protein 1
chr5_-_129864202 1.63 ENSMUST00000136507.4
Psph
phosphoserine phosphatase
chr5_-_36853281 1.51 ENSMUST00000031091.13
ENSMUST00000140653.2
D5Ertd579e
DNA segment, Chr 5, ERATO Doi 579, expressed
chrX_+_41238193 1.50 ENSMUST00000115073.9
ENSMUST00000115072.8
Stag2
stromal antigen 2
chr9_+_119939414 1.48 ENSMUST00000035106.12
Slc25a38
solute carrier family 25, member 38
chr5_+_129864044 1.43 ENSMUST00000201414.5
Cct6a
chaperonin containing Tcp1, subunit 6a (zeta)
chr12_-_104964936 1.41 ENSMUST00000109927.2
ENSMUST00000095439.11
Syne3
spectrin repeat containing, nuclear envelope family member 3
chr6_-_51446850 1.33 ENSMUST00000069949.13
Hnrnpa2b1
heterogeneous nuclear ribonucleoprotein A2/B1
chr1_-_160040286 1.32 ENSMUST00000195654.2
ENSMUST00000014370.11
Cacybp
calcyclin binding protein
chr9_+_18203640 1.32 ENSMUST00000217031.2
Chordc1
cysteine and histidine-rich domain (CHORD)-containing, zinc-binding protein 1
chr2_+_157401998 1.27 ENSMUST00000153739.9
ENSMUST00000173595.2
ENSMUST00000109526.2
ENSMUST00000173839.2
ENSMUST00000173041.8
ENSMUST00000173793.8
ENSMUST00000172487.2
ENSMUST00000088484.6
Nnat
neuronatin
chr5_+_29940686 1.26 ENSMUST00000008733.15
Dnajb6
DnaJ heat shock protein family (Hsp40) member B6
chr6_+_51447317 1.22 ENSMUST00000094623.10
Cbx3
chromobox 3
chr9_+_123902143 1.21 ENSMUST00000168841.3
ENSMUST00000055918.7
Ccr2
chemokine (C-C motif) receptor 2
chr9_+_18203421 1.21 ENSMUST00000001825.9
Chordc1
cysteine and histidine-rich domain (CHORD)-containing, zinc-binding protein 1
chr14_-_66071412 1.13 ENSMUST00000022613.10
Esco2
establishment of sister chromatid cohesion N-acetyltransferase 2
chr8_+_88999031 1.10 ENSMUST00000169037.9
Adcy7
adenylate cyclase 7
chr9_+_18203558 1.04 ENSMUST00000213605.2
Chordc1
cysteine and histidine-rich domain (CHORD)-containing, zinc-binding protein 1
chr17_+_47904355 1.04 ENSMUST00000182209.8
Ccnd3
cyclin D3
chr6_-_136918885 1.01 ENSMUST00000111891.4
Arhgdib
Rho, GDP dissociation inhibitor (GDI) beta
chr11_+_22940519 0.96 ENSMUST00000173867.8
Cct4
chaperonin containing Tcp1, subunit 4 (delta)
chr17_+_47904441 0.95 ENSMUST00000182874.3
Ccnd3
cyclin D3
chr17_-_45883421 0.95 ENSMUST00000130406.2
Hsp90ab1
heat shock protein 90 alpha (cytosolic), class B member 1
chr1_-_55127312 0.94 ENSMUST00000127861.8
ENSMUST00000144077.3
Hspd1
heat shock protein 1 (chaperonin)
chr5_+_30486375 0.92 ENSMUST00000101448.5
Drc1
dynein regulatory complex subunit 1
chrX_-_60229164 0.88 ENSMUST00000166381.3
Cdr1
cerebellar degeneration related antigen 1
chr12_+_105750952 0.87 ENSMUST00000109901.9
ENSMUST00000168186.8
ENSMUST00000163473.8
ENSMUST00000170540.8
ENSMUST00000166735.8
ENSMUST00000170002.8
Papola
poly (A) polymerase alpha
chr16_-_87292592 0.87 ENSMUST00000176750.2
ENSMUST00000175977.8
Cct8
chaperonin containing Tcp1, subunit 8 (theta)
chr9_-_103357564 0.84 ENSMUST00000124310.5
Bfsp2
beaded filament structural protein 2, phakinin
chr11_+_22940599 0.83 ENSMUST00000020562.5
Cct4
chaperonin containing Tcp1, subunit 4 (delta)
chr16_-_22084700 0.83 ENSMUST00000161286.8
Tra2b
transformer 2 beta
chr5_+_29940935 0.80 ENSMUST00000114839.8
ENSMUST00000198694.5
ENSMUST00000012734.10
ENSMUST00000196528.5
Dnajb6
DnaJ heat shock protein family (Hsp40) member B6
chr11_-_5049036 0.79 ENSMUST00000102930.10
ENSMUST00000093365.12
ENSMUST00000073308.11
Ewsr1
Ewing sarcoma breakpoint region 1
chr11_+_83328503 0.78 ENSMUST00000037378.6
1700020L24Rik
RIKEN cDNA 1700020L24 gene
chr5_-_123887434 0.77 ENSMUST00000182955.8
ENSMUST00000182489.8
ENSMUST00000183147.9
ENSMUST00000050827.14
ENSMUST00000057795.12
ENSMUST00000111515.8
ENSMUST00000182309.8
Rsrc2
arginine/serine-rich coiled-coil 2
chr8_-_70411054 0.74 ENSMUST00000211960.2
Gatad2a
GATA zinc finger domain containing 2A
chr16_-_87292711 0.72 ENSMUST00000176041.8
ENSMUST00000026704.14
Cct8
chaperonin containing Tcp1, subunit 8 (theta)
chr11_-_23447866 0.69 ENSMUST00000128559.2
ENSMUST00000147157.8
ENSMUST00000109539.8
Ahsa2
AHA1, activator of heat shock protein ATPase 2
chr2_+_119727689 0.68 ENSMUST00000046717.13
ENSMUST00000079934.12
ENSMUST00000110774.8
ENSMUST00000110773.9
ENSMUST00000156510.2
Mga
MAX gene associated
chr10_-_86541349 0.67 ENSMUST00000020238.14
Hsp90b1
heat shock protein 90, beta (Grp94), member 1
chr7_+_92210348 0.64 ENSMUST00000032842.13
ENSMUST00000085017.5
Ccdc90b
coiled-coil domain containing 90B
chr5_-_149559737 0.63 ENSMUST00000200805.4
Hsph1
heat shock 105kDa/110kDa protein 1
chr1_-_55127183 0.62 ENSMUST00000027123.15
Hspd1
heat shock protein 1 (chaperonin)
chr15_-_31601652 0.61 ENSMUST00000161266.2
Cct5
chaperonin containing Tcp1, subunit 5 (epsilon)
chr8_+_84335176 0.53 ENSMUST00000212300.2
Dnajb1
DnaJ heat shock protein family (Hsp40) member B1
chr9_-_110818679 0.53 ENSMUST00000084922.6
ENSMUST00000199891.2
Rtp3
receptor transporter protein 3
chrX_-_139857424 0.52 ENSMUST00000033805.15
ENSMUST00000112978.2
Psmd10
proteasome (prosome, macropain) 26S subunit, non-ATPase, 10
chr6_+_29853745 0.52 ENSMUST00000064872.13
ENSMUST00000152581.8
ENSMUST00000176265.8
ENSMUST00000154079.8
Ahcyl2
S-adenosylhomocysteine hydrolase-like 2
chr11_-_23448030 0.49 ENSMUST00000020529.13
Ahsa2
AHA1, activator of heat shock protein ATPase 2
chr11_-_5049223 0.48 ENSMUST00000079949.13
Ewsr1
Ewing sarcoma breakpoint region 1
chr7_+_110628158 0.48 ENSMUST00000005749.6
Ctr9
CTR9 homolog, Paf1/RNA polymerase II complex component
chr1_+_91178288 0.48 ENSMUST00000171112.8
ENSMUST00000191533.2
Ube2f
ubiquitin-conjugating enzyme E2F (putative)
chr19_-_7017295 0.48 ENSMUST00000025918.9
Stip1
stress-induced phosphoprotein 1
chr6_-_128415640 0.47 ENSMUST00000032508.11
Fkbp4
FK506 binding protein 4
chr1_+_179788675 0.46 ENSMUST00000076687.12
ENSMUST00000097450.10
ENSMUST00000212756.2
Cdc42bpa
CDC42 binding protein kinase alpha
chr15_-_81284244 0.42 ENSMUST00000172107.8
ENSMUST00000169204.2
ENSMUST00000163382.2
St13
suppression of tumorigenicity 13
chr10_+_59159118 0.42 ENSMUST00000009789.15
ENSMUST00000092512.11
ENSMUST00000105466.3
P4ha1
procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), alpha 1 polypeptide
chr15_-_81283795 0.40 ENSMUST00000023039.15
St13
suppression of tumorigenicity 13
chr4_+_13784749 0.38 ENSMUST00000098256.4
Runx1t1
RUNX1 translocation partner 1
chr9_-_105372235 0.37 ENSMUST00000176190.8
ENSMUST00000163879.9
ENSMUST00000112558.10
ENSMUST00000176363.9
Atp2c1
ATPase, Ca++-sequestering
chr19_-_29790352 0.37 ENSMUST00000099525.5
Ranbp6
RAN binding protein 6
chr11_+_6510167 0.36 ENSMUST00000109722.9
Ccm2
cerebral cavernous malformation 2
chr2_+_163535925 0.34 ENSMUST00000109400.3
Pkig
protein kinase inhibitor, gamma
chr7_+_35285657 0.34 ENSMUST00000040844.16
ENSMUST00000188906.7
ENSMUST00000186245.7
ENSMUST00000190503.7
Ankrd27
ankyrin repeat domain 27 (VPS9 domain)
chr16_-_20245138 0.33 ENSMUST00000079158.13
Abcc5
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
chr15_-_100301124 0.33 ENSMUST00000124324.2
Slc11a2
solute carrier family 11 (proton-coupled divalent metal ion transporters), member 2
chr7_-_89590230 0.32 ENSMUST00000075010.12
Hikeshi
heat shock protein nuclear import factor
chr3_+_117368483 0.31 ENSMUST00000039564.11
ENSMUST00000238937.2
Plppr5
phospholipid phosphatase related 5
chr12_+_117807607 0.30 ENSMUST00000176735.8
ENSMUST00000177339.2
Cdca7l
cell division cycle associated 7 like
chrX_-_149440388 0.29 ENSMUST00000151403.9
ENSMUST00000087253.11
ENSMUST00000112709.8
ENSMUST00000163969.8
ENSMUST00000087258.10
Tro
trophinin
chr16_-_88548523 0.29 ENSMUST00000053149.4
Krtap13
keratin associated protein 13
chr1_+_57813759 0.27 ENSMUST00000167971.8
ENSMUST00000170139.8
ENSMUST00000171699.8
ENSMUST00000164302.8
Spats2l
spermatogenesis associated, serine-rich 2-like
chr6_-_72416531 0.27 ENSMUST00000205335.2
ENSMUST00000206692.2
ENSMUST00000059472.10
Mat2a
methionine adenosyltransferase II, alpha
chr9_+_22322802 0.26 ENSMUST00000058868.9
9530077C05Rik
RIKEN cDNA 9530077C05 gene
chr5_-_143831842 0.25 ENSMUST00000079624.12
ENSMUST00000110717.9
Ankrd61
ankyrin repeat domain 61
chr12_+_24881582 0.24 ENSMUST00000221952.2
ENSMUST00000078902.8
ENSMUST00000110942.11
Mboat2
membrane bound O-acyltransferase domain containing 2
chr13_+_44883270 0.24 ENSMUST00000172830.8
Jarid2
jumonji, AT rich interactive domain 2
chr13_+_44882998 0.23 ENSMUST00000174068.8
Jarid2
jumonji, AT rich interactive domain 2
chr16_-_20245071 0.23 ENSMUST00000115547.9
ENSMUST00000096199.5
Abcc5
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
chr12_-_104718159 0.22 ENSMUST00000041987.7
Dicer1
dicer 1, ribonuclease type III
chr15_+_81284333 0.21 ENSMUST00000163754.9
ENSMUST00000041609.11
Xpnpep3
X-prolyl aminopeptidase 3, mitochondrial
chr7_-_89590334 0.20 ENSMUST00000207309.2
ENSMUST00000130609.3
Hikeshi
heat shock protein nuclear import factor
chr16_-_88571089 0.19 ENSMUST00000054223.4
2310057N15Rik
RIKEN cDNA 2310057N15 gene
chr16_+_88555732 0.19 ENSMUST00000089111.5
2310034C09Rik
RIKEN cDNA 2310034C09 gene
chr17_-_57181420 0.19 ENSMUST00000043062.5
Acsbg2
acyl-CoA synthetase bubblegum family member 2
chr11_-_69768875 0.19 ENSMUST00000178597.3
Tmem95
transmembrane protein 95
chr5_-_66309244 0.16 ENSMUST00000167950.8
Rbm47
RNA binding motif protein 47
chr11_-_116226175 0.16 ENSMUST00000036215.8
Foxj1
forkhead box J1
chr5_-_86616849 0.15 ENSMUST00000101073.3
Tmprss11a
transmembrane protease, serine 11a
chr7_+_140425460 0.15 ENSMUST00000035300.7
Scgb1c1
secretoglobin, family 1C, member 1
chr6_-_128803182 0.14 ENSMUST00000204756.3
ENSMUST00000204394.3
ENSMUST00000204423.3
ENSMUST00000204677.2
ENSMUST00000205130.3
ENSMUST00000174544.2
ENSMUST00000172887.8
ENSMUST00000032472.11
Gm44511
Klrb1b
predicted gene 44511
killer cell lectin-like receptor subfamily B member 1B
chr5_+_66833434 0.14 ENSMUST00000031131.11
Uchl1
ubiquitin carboxy-terminal hydrolase L1
chr11_-_5049082 0.09 ENSMUST00000063232.7
Ewsr1
Ewing sarcoma breakpoint region 1
chrX_-_149440362 0.09 ENSMUST00000148604.2
Tro
trophinin
chr18_-_36899245 0.08 ENSMUST00000061522.8
Dnd1
DND microRNA-mediated repression inhibitor 1
chr7_-_89590404 0.08 ENSMUST00000153470.9
Hikeshi
heat shock protein nuclear import factor
chr17_+_34636321 0.08 ENSMUST00000142317.8
BC051142
cDNA sequence BC051142
chr14_-_66071337 0.07 ENSMUST00000225853.2
Esco2
establishment of sister chromatid cohesion N-acetyltransferase 2
chr7_-_35285001 0.07 ENSMUST00000069912.6
Rgs9bp
regulator of G-protein signalling 9 binding protein
chr19_+_13595285 0.06 ENSMUST00000216688.3
Olfr1487
olfactory receptor 1487
chr17_+_28749808 0.06 ENSMUST00000233837.2
ENSMUST00000025060.4
Armc12
armadillo repeat containing 12
chr17_+_25381414 0.05 ENSMUST00000073277.12
ENSMUST00000182621.8
Ccdc154
coiled-coil domain containing 154
chr15_+_88484484 0.04 ENSMUST00000066949.9
Zdhhc25
zinc finger, DHHC domain containing 25
chr7_-_99002430 0.04 ENSMUST00000094154.6
Serpinh1
serine (or cysteine) peptidase inhibitor, clade H, member 1
chr5_+_149121458 0.03 ENSMUST00000122160.8
ENSMUST00000100410.10
ENSMUST00000119685.8
Uspl1
ubiquitin specific peptidase like 1
chr16_-_55755160 0.03 ENSMUST00000122280.8
ENSMUST00000121703.3
Cep97
centrosomal protein 97
chr3_+_117368876 0.03 ENSMUST00000106473.5
Plppr5
phospholipid phosphatase related 5
chr2_+_72128239 0.03 ENSMUST00000144111.2
Map3k20
mitogen-activated protein kinase kinase kinase 20
chr16_-_64422716 0.03 ENSMUST00000209382.3
Csnka2ip
casein kinase 2, alpha prime interacting protein
chr16_-_94657531 0.02 ENSMUST00000232562.2
ENSMUST00000165538.3
Kcnj6
potassium inwardly-rectifying channel, subfamily J, member 6
chr11_+_104576528 0.02 ENSMUST00000148007.3
ENSMUST00000212287.2
Gm11639
predicted gene 11639
chr12_+_87862140 0.01 ENSMUST00000220585.2
Eif1ad4
eukaryotic translation initiation factor 1A domain containing 4
chr12_-_72283465 0.01 ENSMUST00000021497.16
ENSMUST00000137990.2
Rtn1
reticulon 1
chrX_+_70707271 0.00 ENSMUST00000070449.6
Gpr50
G-protein-coupled receptor 50

Network of associatons between targets according to the STRING database.

First level regulatory network of Hsf1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.6 11.5 GO:0045585 regulation of cytotoxic T cell differentiation(GO:0045583) positive regulation of cytotoxic T cell differentiation(GO:0045585)
1.2 3.6 GO:2000299 negative regulation of Rho-dependent protein serine/threonine kinase activity(GO:2000299)
1.0 3.1 GO:1990428 miRNA transport(GO:1990428)
1.0 2.9 GO:0002149 hypochlorous acid metabolic process(GO:0002148) hypochlorous acid biosynthetic process(GO:0002149)
0.8 7.6 GO:1903753 negative regulation of p38MAPK cascade(GO:1903753)
0.7 2.1 GO:0060715 syncytiotrophoblast cell differentiation involved in labyrinthine layer development(GO:0060715)
0.5 1.6 GO:0045041 protein import into mitochondrial intermembrane space(GO:0045041)
0.4 1.2 GO:1902567 immune complex clearance by monocytes and macrophages(GO:0002436) regulation of immune complex clearance by monocytes and macrophages(GO:0090264) positive regulation of immune complex clearance by monocytes and macrophages(GO:0090265) negative regulation of eosinophil activation(GO:1902567) positive regulation of CD8-positive, alpha-beta T cell extravasation(GO:2000451)
0.4 1.5 GO:0036233 glycine import(GO:0036233)
0.4 5.3 GO:1904871 protein localization to nuclear body(GO:1903405) protein localization to Cajal body(GO:1904867) regulation of protein localization to Cajal body(GO:1904869) positive regulation of protein localization to Cajal body(GO:1904871)
0.3 0.9 GO:0036363 transforming growth factor beta activation(GO:0036363)
0.3 2.2 GO:0071492 cellular response to UV-A(GO:0071492)
0.2 1.2 GO:0034421 post-translational protein acetylation(GO:0034421)
0.2 1.6 GO:0006564 L-serine biosynthetic process(GO:0006564)
0.2 0.5 GO:0070682 proteasome regulatory particle assembly(GO:0070682)
0.2 0.5 GO:2001160 regulation of histone H3-K79 methylation(GO:2001160)
0.1 0.8 GO:0061084 negative regulation of protein refolding(GO:0061084)
0.1 0.3 GO:0035544 negative regulation of SNARE complex assembly(GO:0035544)
0.1 1.0 GO:1901164 negative regulation of trophoblast cell migration(GO:1901164)
0.1 1.1 GO:0032876 negative regulation of DNA endoreduplication(GO:0032876)
0.1 1.4 GO:0090286 cytoskeletal anchoring at nuclear membrane(GO:0090286)
0.1 1.8 GO:0006027 glycosaminoglycan catabolic process(GO:0006027)
0.1 2.0 GO:0030213 hyaluronan biosynthetic process(GO:0030213)
0.1 0.3 GO:0055071 cellular manganese ion homeostasis(GO:0030026) Golgi calcium ion homeostasis(GO:0032468) manganese ion homeostasis(GO:0055071)
0.1 0.7 GO:0021995 anterior neuropore closure(GO:0021506) neuropore closure(GO:0021995)
0.1 1.1 GO:0071361 cellular response to ethanol(GO:0071361)
0.1 0.5 GO:0033353 S-adenosylmethionine cycle(GO:0033353)
0.1 0.3 GO:0015676 vanadium ion transport(GO:0015676) lead ion transport(GO:0015692)
0.1 0.2 GO:0070173 regulation of enamel mineralization(GO:0070173)
0.1 0.2 GO:0002663 B cell tolerance induction(GO:0002514) regulation of B cell tolerance induction(GO:0002661) positive regulation of B cell tolerance induction(GO:0002663)
0.0 0.8 GO:0070307 lens fiber cell development(GO:0070307)
0.0 0.4 GO:0018401 peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401)
0.0 0.3 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
0.0 0.5 GO:0070389 chaperone cofactor-dependent protein refolding(GO:0070389)
0.0 0.8 GO:1990403 embryonic brain development(GO:1990403)
0.0 0.7 GO:0071318 cellular response to ATP(GO:0071318)
0.0 1.3 GO:0060416 response to growth hormone(GO:0060416)
0.0 0.4 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.0 0.5 GO:0051574 positive regulation of histone H3-K9 methylation(GO:0051574)
0.0 0.9 GO:0060285 cilium or flagellum-dependent cell motility(GO:0001539) cilium-dependent cell motility(GO:0060285)
0.0 0.5 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.0 0.4 GO:0060837 blood vessel endothelial cell differentiation(GO:0060837)
0.0 0.9 GO:0031440 regulation of mRNA 3'-end processing(GO:0031440)
0.0 0.5 GO:0031115 negative regulation of microtubule polymerization(GO:0031115)
0.0 0.3 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.0 0.3 GO:0040023 nuclear migration(GO:0007097) establishment of nucleus localization(GO:0040023)
0.0 0.2 GO:0016554 cytidine to uridine editing(GO:0016554)
0.0 0.1 GO:0019896 axonal transport of mitochondrion(GO:0019896)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.9 11.5 GO:0097226 sperm mitochondrial sheath(GO:0097226)
0.3 5.3 GO:0005832 chaperonin-containing T-complex(GO:0005832)
0.2 3.1 GO:0071598 neuronal ribonucleoprotein granule(GO:0071598)
0.2 1.6 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.2 0.9 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
0.2 2.9 GO:0042582 primary lysosome(GO:0005766) azurophil granule(GO:0042582)
0.2 1.2 GO:0035985 senescence-associated heterochromatin focus(GO:0035985)
0.1 1.4 GO:0034993 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.1 0.3 GO:0048269 methionine adenosyltransferase complex(GO:0048269)
0.1 1.3 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.1 0.4 GO:0016222 procollagen-proline 4-dioxygenase complex(GO:0016222)
0.1 1.2 GO:0031618 nuclear pericentric heterochromatin(GO:0031618)
0.1 0.3 GO:0099524 region of cytosol(GO:0099522) postsynaptic cytosol(GO:0099524)
0.1 0.3 GO:0070826 paraferritin complex(GO:0070826)
0.1 0.7 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.0 0.5 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
0.0 1.1 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.0 0.3 GO:0097422 tubular endosome(GO:0097422)
0.0 0.5 GO:0008540 proteasome regulatory particle, base subcomplex(GO:0008540)
0.0 2.0 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0 0.7 GO:0090545 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.0 0.2 GO:0070578 micro-ribonucleoprotein complex(GO:0035068) RISC-loading complex(GO:0070578)
0.0 0.5 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 0.8 GO:0005637 nuclear inner membrane(GO:0005637)
0.0 0.7 GO:0044665 MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.8 12.5 GO:0002135 CTP binding(GO:0002135)
0.7 7.6 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.4 0.8 GO:0032564 dATP binding(GO:0032564)
0.4 1.2 GO:0035717 chemokine (C-C motif) ligand 7 binding(GO:0035717)
0.3 2.2 GO:0016018 cyclosporin A binding(GO:0016018)
0.3 1.4 GO:0071987 WD40-repeat domain binding(GO:0071987)
0.3 3.1 GO:1990247 N6-methyladenosine-containing RNA binding(GO:1990247)
0.3 1.6 GO:0004647 phosphoserine phosphatase activity(GO:0004647)
0.3 1.6 GO:0034186 apolipoprotein A-I binding(GO:0034186)
0.2 0.9 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)
0.1 5.4 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.1 1.0 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.1 1.2 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.1 1.5 GO:0015187 glycine transmembrane transporter activity(GO:0015187)
0.1 0.5 GO:0032767 copper-dependent protein binding(GO:0032767)
0.1 1.1 GO:0004016 adenylate cyclase activity(GO:0004016)
0.1 1.2 GO:1990226 histone methyltransferase binding(GO:1990226)
0.1 0.3 GO:0015410 manganese-transporting ATPase activity(GO:0015410)
0.1 0.5 GO:0031849 olfactory receptor binding(GO:0031849)
0.1 0.5 GO:0004013 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.1 0.4 GO:0004656 procollagen-proline 4-dioxygenase activity(GO:0004656)
0.1 0.3 GO:0004478 methionine adenosyltransferase activity(GO:0004478)
0.1 1.8 GO:0005540 hyaluronic acid binding(GO:0005540)
0.1 0.3 GO:0015094 cadmium ion transmembrane transporter activity(GO:0015086) lead ion transmembrane transporter activity(GO:0015094) vanadium ion transmembrane transporter activity(GO:0015100) ferrous iron uptake transmembrane transporter activity(GO:0015639)
0.1 3.4 GO:0043531 ADP binding(GO:0043531)
0.1 0.7 GO:0046790 virion binding(GO:0046790)
0.0 0.5 GO:0019788 NEDD8 transferase activity(GO:0019788)
0.0 0.2 GO:0032296 ribonuclease III activity(GO:0004525) double-stranded RNA-specific ribonuclease activity(GO:0032296)
0.0 2.9 GO:0004601 peroxidase activity(GO:0004601)
0.0 0.2 GO:0047184 1-acylglycerophosphocholine O-acyltransferase activity(GO:0047184)
0.0 2.0 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
0.0 0.1 GO:0031694 alpha-2A adrenergic receptor binding(GO:0031694)
0.0 1.4 GO:0001671 ATPase activator activity(GO:0001671)
0.0 0.3 GO:0042577 lipid phosphatase activity(GO:0042577)
0.0 0.8 GO:0070717 poly-purine tract binding(GO:0070717)
0.0 1.1 GO:0030544 Hsp70 protein binding(GO:0030544)
0.0 0.3 GO:0004862 cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.0 0.5 GO:0000993 RNA polymerase II core binding(GO:0000993)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 11.5 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0 2.9 PID IL23 PATHWAY IL23-mediated signaling events
0.0 1.1 PID LPA4 PATHWAY LPA4-mediated signaling events
0.0 1.4 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.0 2.0 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.0 1.4 PID BARD1 PATHWAY BARD1 signaling events
0.0 2.2 PID CMYB PATHWAY C-MYB transcription factor network
0.0 0.7 PID IL6 7 PATHWAY IL6-mediated signaling events
0.0 0.4 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.0 0.9 PID PLK1 PATHWAY PLK1 signaling events
0.0 1.0 PID CASPASE PATHWAY Caspase cascade in apoptosis

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 11.5 REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.2 5.3 REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC Genes involved in Formation of tubulin folding intermediates by CCT/TriC
0.1 1.8 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.1 1.2 REACTOME BETA DEFENSINS Genes involved in Beta defensins
0.1 0.6 REACTOME HYALURONAN METABOLISM Genes involved in Hyaluronan metabolism
0.1 0.7 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.1 1.1 REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY Genes involved in Adenylate cyclase activating pathway
0.1 0.9 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.1 1.6 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.0 0.9 REACTOME PROCESSING OF INTRONLESS PRE MRNAS Genes involved in Processing of Intronless Pre-mRNAs
0.0 2.0 REACTOME G1 PHASE Genes involved in G1 Phase
0.0 1.6 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.0 1.2 REACTOME RNA POL I TRANSCRIPTION Genes involved in RNA Polymerase I Transcription
0.0 0.2 REACTOME MICRORNA MIRNA BIOGENESIS Genes involved in MicroRNA (miRNA) Biogenesis
0.0 3.1 REACTOME MRNA SPLICING Genes involved in mRNA Splicing
0.0 1.1 REACTOME MEIOTIC SYNAPSIS Genes involved in Meiotic Synapsis