Project

GSE58827: Dynamics of the Mouse Liver

Navigation
Downloads

Results for Insm1

Z-value: 0.89

Motif logo

Transcription factors associated with Insm1

Gene Symbol Gene ID Gene Info
ENSMUSG00000068154.6 insulinoma-associated 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Insm1mm39_v1_chr2_+_146063841_1460638410.401.5e-02Click!

Activity profile of Insm1 motif

Sorted Z-values of Insm1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr7_+_78563964 9.44 ENSMUST00000120331.4
interferon-stimulated protein
chr7_+_78563513 7.44 ENSMUST00000038142.15
interferon-stimulated protein
chr7_+_78564062 7.41 ENSMUST00000205981.2
interferon-stimulated protein
chr7_-_125968653 5.20 ENSMUST00000205642.2
ENSMUST00000032997.8
ENSMUST00000206793.2
linker for activation of T cells
chr2_+_90912710 5.18 ENSMUST00000169852.2
spleen focus forming virus (SFFV) proviral integration oncogene
chr17_+_25235310 4.79 ENSMUST00000024983.12
intraflagellar transport 140
chr19_+_4204605 4.37 ENSMUST00000061086.9
protein tyrosine phosphatase, receptor type, C polypeptide-associated protein
chr7_+_27173187 4.17 ENSMUST00000068641.8
SERTA domain containing 3
chr3_-_104725853 3.97 ENSMUST00000106775.8
ENSMUST00000166979.8
Mov10 RISC complex RNA helicase
chr4_-_44710408 3.75 ENSMUST00000134968.9
ENSMUST00000173821.8
ENSMUST00000174319.8
ENSMUST00000173733.8
ENSMUST00000172866.8
ENSMUST00000165417.9
ENSMUST00000107825.9
ENSMUST00000102932.10
ENSMUST00000107827.9
ENSMUST00000107826.9
ENSMUST00000014174.14
paired box 5
chr17_+_25235039 3.74 ENSMUST00000142000.9
ENSMUST00000137386.8
intraflagellar transport 140
chr2_-_152673032 3.73 ENSMUST00000128172.3
BCL2-like 1
chrX_+_9138995 3.60 ENSMUST00000015486.7
X-linked Kx blood group
chr3_-_104725581 3.51 ENSMUST00000168015.8
Mov10 RISC complex RNA helicase
chr7_+_140711181 3.49 ENSMUST00000026568.10
phosphatidylserine synthase 2
chr2_+_30176395 3.44 ENSMUST00000064447.12
nucleoporin 188
chr19_-_5713648 3.42 ENSMUST00000080824.13
ENSMUST00000237874.2
ENSMUST00000071857.13
ENSMUST00000236464.2
signal-induced proliferation associated gene 1
chr3_-_104725535 3.35 ENSMUST00000002297.12
Mov10 RISC complex RNA helicase
chr17_-_35827676 3.23 ENSMUST00000160885.2
ENSMUST00000159009.2
ENSMUST00000161012.8
transcription factor 19
chr19_-_5713701 2.81 ENSMUST00000164304.9
ENSMUST00000237544.2
signal-induced proliferation associated gene 1
chr14_+_56091454 2.78 ENSMUST00000227465.2
ENSMUST00000168479.3
ENSMUST00000100529.10
NYN domain and retroviral integrase containing
chr7_-_110581652 2.73 ENSMUST00000005751.13
inositol 1,4,5-triphosphate receptor associated 1
chr7_+_4743114 2.72 ENSMUST00000098853.9
ENSMUST00000130215.8
ENSMUST00000108582.10
ENSMUST00000108583.9
lysine methyltransferase 5C
chr10_-_42152684 2.47 ENSMUST00000175881.8
ENSMUST00000056974.4
ENSMUST00000105502.8
ENSMUST00000105501.2
forkhead box O3
chr2_-_152673585 2.37 ENSMUST00000156688.2
ENSMUST00000007803.12
BCL2-like 1
chr17_+_29020064 2.29 ENSMUST00000004985.11
bromodomain and PHD finger containing, 3
chr15_-_100320926 2.24 ENSMUST00000023774.12
solute carrier family 11 (proton-coupled divalent metal ion transporters), member 2
chr1_+_87548026 2.10 ENSMUST00000169754.8
ENSMUST00000042275.15
ENSMUST00000168783.8
inositol polyphosphate-5-phosphatase D
chr15_-_99268311 1.94 ENSMUST00000081224.14
ENSMUST00000120633.2
ENSMUST00000088233.13
formin-like 3
chr7_+_65710086 1.93 ENSMUST00000153609.8
small nuclear ribonucleoprotein polypeptide A'
chr15_-_103242697 1.76 ENSMUST00000229373.2
zinc finger protein 385A
chr10_-_127024641 1.73 ENSMUST00000218654.2
Rho guanine nucleotide exchange factor (GEF) 25
chr12_-_113561594 1.71 ENSMUST00000103444.3
immunoglobulin heavy variable 5-4
chr6_-_128332789 1.70 ENSMUST00000001562.9
tubby-like protein 3
chr4_-_128699838 1.70 ENSMUST00000106072.9
ENSMUST00000170934.3
zinc finger protein 362
chr5_-_123038329 1.67 ENSMUST00000031435.14
lysine (K)-specific demethylase 2B
chr11_-_115704447 1.54 ENSMUST00000041684.11
ENSMUST00000156812.2
CASK-interacting protein 2
chr7_+_25760922 1.49 ENSMUST00000005669.9
cytochrome P450, family 2, subfamily b, polypeptide 13
chr18_+_34910064 1.43 ENSMUST00000043775.9
ENSMUST00000224715.2
KDM3B lysine (K)-specific demethylase 3B
chr2_+_30176418 1.33 ENSMUST00000138666.8
ENSMUST00000113634.3
nucleoporin 188
chr7_+_127345909 1.28 ENSMUST00000033081.14
F-box and leucine-rich repeat protein 19
chr15_-_76702170 1.23 ENSMUST00000175843.3
ENSMUST00000177026.3
ENSMUST00000176736.3
ENSMUST00000036176.16
ENSMUST00000176219.9
ENSMUST00000239134.2
ENSMUST00000239003.2
ENSMUST00000077821.10
Rho GTPase activating protein 39
chr7_+_101583283 1.22 ENSMUST00000209639.2
ENSMUST00000210679.2
nuclear mitotic apparatus protein 1
chr7_+_127376550 1.21 ENSMUST00000126761.8
ENSMUST00000047157.13
SET domain containing 1A
chr7_-_118594365 1.20 ENSMUST00000008878.10
G protein-coupled receptor, family C, group 5, member B
chr7_+_100021425 1.14 ENSMUST00000098259.11
ENSMUST00000051777.15
C2 calcium-dependent domain containing 3
chr4_-_130068484 1.12 ENSMUST00000132545.3
ENSMUST00000175992.8
ENSMUST00000105999.9
tubulointerstitial nephritis antigen-like 1
chr6_+_38086190 1.09 ENSMUST00000031851.5
transmembrane protein 213
chr7_+_127078371 1.05 ENSMUST00000205432.3
fibrosin
chr4_-_108240546 1.00 ENSMUST00000053157.7
shisa like 2A
chr19_+_6952580 0.97 ENSMUST00000237084.2
ENSMUST00000236218.2
ENSMUST00000237235.2
protein phosphatase 1, regulatory inhibitor subunit 14B
chr19_+_6952319 0.94 ENSMUST00000070850.8
protein phosphatase 1, regulatory inhibitor subunit 14B
chr9_+_106354463 0.93 ENSMUST00000047721.10
ribosomal RNA processing 9, U3 small nucleolar RNA binding protein
chr6_-_38086484 0.93 ENSMUST00000114908.5
ATPase, H+ transporting, lysosomal V0 subunit A4
chr17_+_26882171 0.91 ENSMUST00000236346.2
ATPase, H+ transporting, lysosomal V0 subunit E
chr2_+_26473870 0.89 ENSMUST00000100290.13
ENSMUST00000238983.2
ENSMUST00000102907.13
EGF-like domain 7
chr10_-_19727165 0.85 ENSMUST00000059805.6
solute carrier family 35, member D3
chr12_-_70158694 0.85 ENSMUST00000223257.2
ENSMUST00000169074.2
ENSMUST00000021468.14
ninein
chr10_+_74802996 0.84 ENSMUST00000037813.5
guanine nucleotide binding protein, alpha z subunit
chr7_+_110628158 0.82 ENSMUST00000005749.6
CTR9 homolog, Paf1/RNA polymerase II complex component
chr13_+_45543208 0.79 ENSMUST00000038275.11
myosin regulatory light chain interacting protein
chr7_+_141040988 0.75 ENSMUST00000053670.12
calcium release activated channel regulator 2B
chr7_-_44665639 0.75 ENSMUST00000085383.11
SR-related CTD-associated factor 1
chr4_-_133972890 0.73 ENSMUST00000030644.8
zinc finger protein 593
chr5_-_125511117 0.71 ENSMUST00000169485.6
DEAH (Asp-Glu-Ala-His) box polypeptide 37
chr5_+_149121458 0.69 ENSMUST00000122160.8
ENSMUST00000100410.10
ENSMUST00000119685.8
ubiquitin specific peptidase like 1
chr7_-_30251680 0.68 ENSMUST00000215288.2
ENSMUST00000108165.8
ENSMUST00000153594.3
proline and serine rich 3
chr12_-_70158739 0.68 ENSMUST00000222835.2
ENSMUST00000221275.2
ENSMUST00000095666.13
ninein
chr2_+_28095660 0.68 ENSMUST00000102879.4
ENSMUST00000028177.11
olfactomedin 1
chr8_+_95781722 0.67 ENSMUST00000058479.7
dynein regulatory complex subunit 7
chr15_-_100976370 0.67 ENSMUST00000213610.2
fidgetin-like 2
chr8_+_125624615 0.67 ENSMUST00000034467.7
SprT-like N-terminal domain
chr2_+_51962831 0.65 ENSMUST00000112693.10
replication timing regulatory factor 1
chr15_+_78312851 0.65 ENSMUST00000159771.8
potassium channel tetramerisation domain containing 17
chr16_-_18066591 0.64 ENSMUST00000115645.10
RAN binding protein 1
chr7_-_100021514 0.62 ENSMUST00000032963.10
protein phosphatase methylesterase 1
chr15_+_78312764 0.60 ENSMUST00000162517.8
ENSMUST00000166142.10
ENSMUST00000089414.11
potassium channel tetramerisation domain containing 17
chr7_-_19449319 0.58 ENSMUST00000032555.10
ENSMUST00000093552.12
translocase of outer mitochondrial membrane 40
chr5_-_31359559 0.58 ENSMUST00000202929.2
ENSMUST00000201231.2
ENSMUST00000114590.8
zinc finger protein 513
chr11_+_105975403 0.56 ENSMUST00000002044.10
mitogen-activated protein kinase kinase kinase 3
chr7_-_110581376 0.56 ENSMUST00000154466.2
inositol 1,4,5-triphosphate receptor associated 1
chr5_+_149121488 0.54 ENSMUST00000139474.8
ENSMUST00000117878.8
ubiquitin specific peptidase like 1
chr9_-_119812829 0.53 ENSMUST00000216929.2
cysteine-serine-rich nuclear protein 1
chr1_+_64571942 0.52 ENSMUST00000171164.8
ENSMUST00000187811.7
ENSMUST00000049932.12
ENSMUST00000087366.11
cAMP responsive element binding protein 1
chr12_-_12990584 0.52 ENSMUST00000130990.2
v-myc avian myelocytomatosis viral related oncogene, neuroblastoma derived
chr10_+_85665234 0.51 ENSMUST00000217667.2
PWP1 homolog, endonuclein
chr13_+_16186410 0.50 ENSMUST00000042603.14
inhibin beta-A
chr5_-_122402451 0.50 ENSMUST00000111738.8
tectonic family member 1
chr3_+_145643760 0.49 ENSMUST00000039571.14
RIKEN cDNA 2410004B18 gene
chr2_-_165726610 0.47 ENSMUST00000177633.8
ENSMUST00000018050.14
ENSMUST00000088113.11
zinc finger, MYND-type containing 8
chr18_-_33597060 0.46 ENSMUST00000168890.2
neuronal regeneration related protein
chr12_-_113393106 0.45 ENSMUST00000192746.2
ENSMUST00000103429.2
immunoglobulin heavy joining 2
chr18_-_33596890 0.44 ENSMUST00000237066.2
neuronal regeneration related protein
chr2_+_25132941 0.44 ENSMUST00000114355.2
ENSMUST00000060818.2
ring finger protein 208
chr12_+_77285770 0.43 ENSMUST00000062804.8
fucosyltransferase 8
chr16_+_18066730 0.42 ENSMUST00000115640.8
ENSMUST00000140206.8
TRM2 tRNA methyltransferase 2A
chr6_-_97125817 0.41 ENSMUST00000204331.3
ENSMUST00000142116.2
ENSMUST00000113387.8
EGF domain-specific O-linked N-acetylglucosamine (GlcNAc) transferase
chr5_+_149121355 0.37 ENSMUST00000050472.16
ubiquitin specific peptidase like 1
chr14_-_55163311 0.35 ENSMUST00000022813.8
embryonal Fyn-associated substrate
chr17_+_35827997 0.34 ENSMUST00000164242.9
ENSMUST00000045956.14
coiled-coil alpha-helical rod protein 1
chr2_+_174171979 0.32 ENSMUST00000109083.2
GNAS (guanine nucleotide binding protein, alpha stimulating) complex locus
chr11_-_115590318 0.30 ENSMUST00000106497.8
growth factor receptor bound protein 2
chr16_+_18066825 0.30 ENSMUST00000100099.10
TRM2 tRNA methyltransferase 2A
chr3_+_31149201 0.28 ENSMUST00000118470.8
ENSMUST00000029194.12
ENSMUST00000123532.2
SKI-like
chr12_-_113392728 0.28 ENSMUST00000103428.2
immunoglobulin heavy joining 3
chr18_-_33596792 0.27 ENSMUST00000051087.16
neuronal regeneration related protein
chr10_-_82459024 0.27 ENSMUST00000183363.2
ENSMUST00000079648.12
ENSMUST00000185168.8
RIKEN cDNA 1190007I07 gene
chrX_-_52672363 0.24 ENSMUST00000088778.5
retrotransposon Gag like 8B
chr2_-_127363251 0.24 ENSMUST00000028850.15
ENSMUST00000103215.11
Kv channel interacting protein 3, calsenilin
chr19_+_5687503 0.22 ENSMUST00000025867.6
v-rel reticuloendotheliosis viral oncogene homolog A (avian)
chr14_-_55163452 0.21 ENSMUST00000227037.2
embryonal Fyn-associated substrate
chr4_+_133970973 0.20 ENSMUST00000135228.8
ENSMUST00000144222.8
ENSMUST00000143448.8
ENSMUST00000125921.8
ENSMUST00000122952.8
ENSMUST00000131447.2
RIKEN cDNA E130218I03 gene
chr5_-_100648487 0.20 ENSMUST00000239512.1
lin-54 homolog (C. elegans)
chr9_+_108685555 0.18 ENSMUST00000035218.9
ENSMUST00000195323.2
ENSMUST00000194819.2
NCK interacting protein with SH3 domain
chr6_-_131293361 0.18 ENSMUST00000121078.2
serine/threonine/tyrosine kinase 1
chr2_-_121185765 0.17 ENSMUST00000134796.3
ENSMUST00000110628.8
ENSMUST00000110627.8
ENSMUST00000110625.8
diphosphoinositol pentakisphosphate kinase 1
chrX_+_67722390 0.17 ENSMUST00000114654.8
ENSMUST00000114655.8
ENSMUST00000114657.9
ENSMUST00000114653.2
FMRP translational regulator 1
chr5_-_137739364 0.17 ENSMUST00000149512.3
neuronal tyrosine-phosphorylated phosphoinositide 3-kinase adaptor 1
chr6_-_85046430 0.13 ENSMUST00000160197.6
exocyst complex component 6B
chr9_-_44792575 0.12 ENSMUST00000114689.8
ENSMUST00000002095.11
ENSMUST00000128768.3
lysine (K)-specific methyltransferase 2A
chr12_-_114370581 0.11 ENSMUST00000191918.2
immunoglobulin heavy variable V6-4
chr11_-_115590133 0.11 ENSMUST00000106499.8
growth factor receptor bound protein 2
chr7_+_45522551 0.10 ENSMUST00000211234.2
KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1
chr9_+_56979307 0.09 ENSMUST00000169879.8
transcriptional regulator, SIN3A (yeast)
chr14_+_54862762 0.09 ENSMUST00000097177.5
proteasome (prosome, macropain) subunit, beta type, 11
chr8_+_82069177 0.09 ENSMUST00000213285.2
ENSMUST00000217122.2
ENSMUST00000215332.2
inositol polyphosphate-4-phosphatase, type II
chr11_-_59029996 0.08 ENSMUST00000219084.3
obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF
chr9_+_77543776 0.08 ENSMUST00000057781.8
kelch-like 31
chr11_-_69771797 0.07 ENSMUST00000238978.2
potassium channel tetramerisation domain containing 11
chr1_-_171854818 0.07 ENSMUST00000138714.2
ENSMUST00000027837.13
ENSMUST00000111264.8
VANGL planar cell polarity 2
chrX_-_154406114 0.07 ENSMUST00000170236.2
patched domain containing 1
chr13_-_58056089 0.04 ENSMUST00000185502.7
ENSMUST00000186271.7
ENSMUST00000185905.2
ENSMUST00000187852.7
sparc/osteonectin, cwcv and kazal-like domains proteoglycan 1
chrX_+_99019176 0.03 ENSMUST00000113781.8
ENSMUST00000113783.8
ENSMUST00000113779.8
ENSMUST00000113776.8
ENSMUST00000113775.8
ENSMUST00000113780.8
ENSMUST00000113778.8
ENSMUST00000113777.8
ENSMUST00000071453.3
ectodysplasin-A
chr4_+_134042423 0.01 ENSMUST00000105875.8
ENSMUST00000030638.7
tripartite motif-containing 63
chr7_-_45463701 0.01 ENSMUST00000210898.2
ENSMUST00000107729.10
ENSMUST00000056820.13
cytohesin 2
chr13_-_18556626 0.01 ENSMUST00000139064.10
ENSMUST00000175703.9
POU domain, class 6, transcription factor 2
chrX_+_151789457 0.00 ENSMUST00000095755.4
ubiquitin specific protease 51

Network of associatons between targets according to the STRING database.

First level regulatory network of Insm1

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
4.0 24.3 GO:0000738 DNA catabolic process, exonucleolytic(GO:0000738)
2.7 10.8 GO:0098795 mRNA cleavage involved in gene silencing by miRNA(GO:0035279) mRNA cleavage involved in gene silencing(GO:0098795)
1.5 6.1 GO:0046898 response to cycloheximide(GO:0046898)
1.2 6.2 GO:0042631 cellular response to water deprivation(GO:0042631)
1.0 5.2 GO:0045347 negative regulation of MHC class II biosynthetic process(GO:0045347)
0.7 4.8 GO:0090521 glomerular visceral epithelial cell migration(GO:0090521)
0.7 8.5 GO:0035845 photoreceptor cell outer segment organization(GO:0035845)
0.6 3.6 GO:0031133 regulation of axon diameter(GO:0031133)
0.5 2.1 GO:0045659 negative regulation of neutrophil differentiation(GO:0045659)
0.5 3.5 GO:0006659 phosphatidylserine biosynthetic process(GO:0006659)
0.4 1.8 GO:0010609 mRNA localization resulting in posttranscriptional regulation of gene expression(GO:0010609) positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902164)
0.4 1.7 GO:0060434 bronchus morphogenesis(GO:0060434)
0.4 1.7 GO:0021993 initiation of neural tube closure(GO:0021993)
0.4 1.5 GO:0090222 centrosome-templated microtubule nucleation(GO:0090222)
0.4 2.5 GO:1901300 positive regulation of hydrogen peroxide-mediated programmed cell death(GO:1901300)
0.3 1.6 GO:0030576 Cajal body organization(GO:0030576)
0.3 1.2 GO:0032887 regulation of spindle elongation(GO:0032887) regulation of mitotic spindle elongation(GO:0032888) anastral spindle assembly(GO:0055048) protein localization to spindle pole body(GO:0071988) regulation of protein localization to spindle pole body(GO:1902363) positive regulation of protein localization to spindle pole body(GO:1902365) positive regulation of mitotic spindle elongation(GO:1902846)
0.3 0.9 GO:0090481 pyrimidine nucleotide-sugar transmembrane transport(GO:0090481)
0.3 5.2 GO:0006968 cellular defense response(GO:0006968)
0.3 0.8 GO:2001160 regulation of histone H3-K79 methylation(GO:2001160)
0.3 3.2 GO:0034773 histone H4-K20 trimethylation(GO:0034773)
0.3 2.8 GO:0015074 DNA integration(GO:0015074)
0.2 0.6 GO:2001034 positive regulation of double-strand break repair via nonhomologous end joining(GO:2001034)
0.2 3.8 GO:0021670 lateral ventricle development(GO:0021670)
0.2 1.2 GO:0015676 vanadium ion transport(GO:0015676) lead ion transport(GO:0015692)
0.2 1.1 GO:0061511 neural plate axis specification(GO:0021997) centriole elongation(GO:0061511)
0.2 1.4 GO:0072718 response to cisplatin(GO:0072718)
0.2 0.6 GO:0046604 positive regulation of mitotic centrosome separation(GO:0046604)
0.2 0.5 GO:1904550 chemotaxis to arachidonic acid(GO:0034670) response to arachidonic acid(GO:1904550)
0.1 0.8 GO:0010989 negative regulation of low-density lipoprotein particle clearance(GO:0010989)
0.1 1.2 GO:1902036 regulation of hematopoietic stem cell differentiation(GO:1902036)
0.1 0.5 GO:0060279 positive regulation of ovulation(GO:0060279)
0.1 0.5 GO:1904491 protein localization to ciliary transition zone(GO:1904491)
0.1 1.2 GO:0060907 positive regulation of macrophage cytokine production(GO:0060907)
0.1 3.2 GO:0044342 type B pancreatic cell proliferation(GO:0044342)
0.1 0.7 GO:1903026 negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding(GO:1903026)
0.1 0.5 GO:1903758 regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903756) negative regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903758)
0.1 0.9 GO:0070072 vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
0.1 0.4 GO:0033578 protein glycosylation in Golgi(GO:0033578)
0.1 0.7 GO:0023041 neuronal signal transduction(GO:0023041)
0.0 1.5 GO:0019373 epoxygenase P450 pathway(GO:0019373)
0.0 0.2 GO:0071224 cellular response to peptidoglycan(GO:0071224)
0.0 0.5 GO:2000980 regulation of auditory receptor cell differentiation(GO:0045607) regulation of mechanoreceptor differentiation(GO:0045631) regulation of inner ear receptor cell differentiation(GO:2000980)
0.0 0.7 GO:0019985 translesion synthesis(GO:0019985)
0.0 0.8 GO:2001256 regulation of store-operated calcium entry(GO:2001256)
0.0 1.2 GO:0045724 positive regulation of cilium assembly(GO:0045724)
0.0 0.3 GO:0040032 post-embryonic body morphogenesis(GO:0040032)
0.0 0.1 GO:0061341 non-canonical Wnt signaling pathway involved in heart development(GO:0061341) planar cell polarity pathway involved in heart morphogenesis(GO:0061346)
0.0 0.2 GO:1901674 histone H3-K27 acetylation(GO:0043974) regulation of histone H3-K27 acetylation(GO:1901674)
0.0 0.6 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
0.0 0.9 GO:0015991 ATP hydrolysis coupled proton transport(GO:0015991)
0.0 2.3 GO:0043966 histone H3 acetylation(GO:0043966)
0.0 0.7 GO:0010569 regulation of double-strand break repair via homologous recombination(GO:0010569)
0.0 0.9 GO:0045746 negative regulation of Notch signaling pathway(GO:0045746)
0.0 0.4 GO:0060670 branching involved in labyrinthine layer morphogenesis(GO:0060670)
0.0 0.6 GO:0008214 protein demethylation(GO:0006482) protein dealkylation(GO:0008214)
0.0 0.1 GO:0006621 protein retention in ER lumen(GO:0006621)
0.0 0.0 GO:0061152 trachea submucosa development(GO:0061152) trachea gland development(GO:0061153)
0.0 0.2 GO:0006020 inositol metabolic process(GO:0006020)
0.0 1.8 GO:0006910 phagocytosis, recognition(GO:0006910)
0.0 0.2 GO:1902231 positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902231)
0.0 3.0 GO:0030308 negative regulation of cell growth(GO:0030308)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 10.2 GO:0030991 intraciliary transport particle A(GO:0030991)
0.7 4.8 GO:0044611 nuclear pore inner ring(GO:0044611)
0.5 6.1 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.4 24.4 GO:0015030 Cajal body(GO:0015030)
0.3 2.3 GO:0070775 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.2 1.2 GO:0061673 mitotic spindle astral microtubule(GO:0061673)
0.2 1.2 GO:0070826 paraferritin complex(GO:0070826)
0.2 0.9 GO:0031428 box C/D snoRNP complex(GO:0031428)
0.2 0.5 GO:0043512 inhibin A complex(GO:0043512)
0.1 1.8 GO:0033179 proton-transporting V-type ATPase, V0 domain(GO:0033179)
0.1 0.5 GO:1990589 ATF4-CREB1 transcription factor complex(GO:1990589)
0.1 5.8 GO:0008180 COP9 signalosome(GO:0008180)
0.1 1.9 GO:0005686 U2 snRNP(GO:0005686)
0.1 0.8 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
0.1 1.5 GO:0097539 ciliary transition fiber(GO:0097539)
0.1 2.7 GO:0000780 condensed nuclear chromosome, centromeric region(GO:0000780)
0.1 10.3 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.1 1.2 GO:0048188 Set1C/COMPASS complex(GO:0048188)
0.1 0.6 GO:0001940 male pronucleus(GO:0001940)
0.0 0.6 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.0 1.1 GO:0034451 centriolar satellite(GO:0034451)
0.0 0.6 GO:1904115 axon cytoplasm(GO:1904115)
0.0 0.5 GO:0036038 MKS complex(GO:0036038)
0.0 0.1 GO:0005863 striated muscle myosin thick filament(GO:0005863)
0.0 0.4 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.0 0.1 GO:0060187 cell pole(GO:0060187)
0.0 1.7 GO:0031519 PcG protein complex(GO:0031519)
0.0 0.7 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.0 3.8 GO:0001650 fibrillar center(GO:0001650)
0.0 0.7 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.0 0.2 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.0 1.2 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 1.3 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 1.3 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 1.8 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.0 6.2 GO:0030133 transport vesicle(GO:0030133)
0.0 2.1 GO:0030863 cortical cytoskeleton(GO:0030863)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
4.9 24.3 GO:0008859 exoribonuclease II activity(GO:0008859)
0.6 6.1 GO:0051434 BH3 domain binding(GO:0051434)
0.5 1.6 GO:0070140 isopeptidase activity(GO:0070122) ubiquitin-like protein-specific isopeptidase activity(GO:0070138) SUMO-specific isopeptidase activity(GO:0070140)
0.4 2.7 GO:0042799 histone methyltransferase activity (H4-K20 specific)(GO:0042799)
0.4 1.9 GO:0030620 U2 snRNA binding(GO:0030620)
0.3 5.2 GO:0051525 NFAT protein binding(GO:0051525)
0.3 3.5 GO:0017169 CDP-alcohol phosphatidyltransferase activity(GO:0017169)
0.3 2.1 GO:0016312 inositol bisphosphate phosphatase activity(GO:0016312) PTB domain binding(GO:0051425)
0.2 1.2 GO:1990188 euchromatin binding(GO:1990188)
0.2 0.9 GO:0034511 U3 snoRNA binding(GO:0034511)
0.2 1.2 GO:0015100 cadmium ion transmembrane transporter activity(GO:0015086) lead ion transmembrane transporter activity(GO:0015094) vanadium ion transmembrane transporter activity(GO:0015100) ferrous iron uptake transmembrane transporter activity(GO:0015639)
0.2 4.8 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.1 0.4 GO:0016262 protein N-acetylglucosaminyltransferase activity(GO:0016262)
0.1 1.4 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.1 0.5 GO:1990763 arrestin family protein binding(GO:1990763)
0.1 0.8 GO:0031821 G-protein coupled serotonin receptor binding(GO:0031821)
0.1 0.9 GO:0015165 pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165)
0.1 5.6 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.1 1.7 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.1 0.7 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.1 1.9 GO:0032794 GTPase activating protein binding(GO:0032794)
0.1 0.5 GO:0070699 type II activin receptor binding(GO:0070699)
0.1 1.2 GO:0051011 microtubule minus-end binding(GO:0051011)
0.1 0.6 GO:0015288 porin activity(GO:0015288)
0.1 1.8 GO:0046961 proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.1 11.2 GO:0004386 helicase activity(GO:0004386)
0.0 1.2 GO:0097602 cullin family protein binding(GO:0097602)
0.0 1.5 GO:0008392 arachidonic acid epoxygenase activity(GO:0008392)
0.0 2.5 GO:0001221 transcription cofactor binding(GO:0001221)
0.0 0.4 GO:0008417 fucosyltransferase activity(GO:0008417)
0.0 0.3 GO:0051430 corticotropin-releasing hormone receptor 1 binding(GO:0051430)
0.0 0.2 GO:0071532 ankyrin repeat binding(GO:0071532)
0.0 0.1 GO:0045322 unmethylated CpG binding(GO:0045322)
0.0 0.2 GO:0052723 inositol hexakisphosphate kinase activity(GO:0000828) inositol hexakisphosphate 5-kinase activity(GO:0000832) inositol hexakisphosphate 1-kinase activity(GO:0052723) inositol hexakisphosphate 3-kinase activity(GO:0052724)
0.0 0.8 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.0 1.5 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.0 1.1 GO:0043236 laminin binding(GO:0043236)
0.0 0.6 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
0.0 0.9 GO:0005112 Notch binding(GO:0005112)
0.0 0.1 GO:0016316 phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316) phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity(GO:0034597)
0.0 0.5 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.0 0.1 GO:0046923 ER retention sequence binding(GO:0046923)
0.0 1.8 GO:0002039 p53 binding(GO:0002039)
0.0 0.6 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 6.2 GO:0005096 GTPase activator activity(GO:0005096)
0.0 1.8 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.0 1.2 GO:0030295 protein kinase activator activity(GO:0030295)
0.0 1.5 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 5.2 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.3 6.1 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.1 8.1 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.0 2.1 ST INTERLEUKIN 4 PATHWAY Interleukin 4 (IL-4) Pathway
0.0 0.8 PID S1P S1P4 PATHWAY S1P4 pathway
0.0 6.2 PID PDGFRB PATHWAY PDGFR-beta signaling pathway
0.0 1.4 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.0 1.9 PID ILK PATHWAY Integrin-linked kinase signaling
0.0 0.6 PID P38 ALPHA BETA PATHWAY Regulation of p38-alpha and p38-beta
0.0 2.1 PID CMYB PATHWAY C-MYB transcription factor network
0.0 1.2 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.0 0.2 PID NFKAPPAB ATYPICAL PATHWAY Atypical NF-kappaB pathway
0.0 0.6 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.0 0.5 PID ALK1 PATHWAY ALK1 signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 24.3 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.3 10.8 REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION Genes involved in Pre-NOTCH Transcription and Translation
0.3 6.1 REACTOME INFLAMMASOMES Genes involved in Inflammasomes
0.2 6.2 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.1 5.2 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
0.1 4.8 REACTOME TRANSPORT OF RIBONUCLEOPROTEINS INTO THE HOST NUCLEUS Genes involved in Transport of Ribonucleoproteins into the Host Nucleus
0.1 2.5 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.1 1.2 REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES Genes involved in Recruitment of NuMA to mitotic centrosomes
0.0 0.5 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.0 0.4 REACTOME CD28 DEPENDENT VAV1 PATHWAY Genes involved in CD28 dependent Vav1 pathway
0.0 0.3 REACTOME PROSTACYCLIN SIGNALLING THROUGH PROSTACYCLIN RECEPTOR Genes involved in Prostacyclin signalling through prostacyclin receptor
0.0 0.9 REACTOME INSULIN RECEPTOR RECYCLING Genes involved in Insulin receptor recycling
0.0 0.5 REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB Genes involved in PKA-mediated phosphorylation of CREB
0.0 0.8 REACTOME G PROTEIN ACTIVATION Genes involved in G-protein activation
0.0 0.2 REACTOME NFKB IS ACTIVATED AND SIGNALS SURVIVAL Genes involved in NF-kB is activated and signals survival
0.0 0.4 REACTOME N GLYCAN ANTENNAE ELONGATION IN THE MEDIAL TRANS GOLGI Genes involved in N-glycan antennae elongation in the medial/trans-Golgi
0.0 1.7 REACTOME GLYCEROPHOSPHOLIPID BIOSYNTHESIS Genes involved in Glycerophospholipid biosynthesis
0.0 1.9 REACTOME MRNA SPLICING Genes involved in mRNA Splicing
0.0 0.6 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.0 1.4 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+