GSE58827: Dynamics of the Mouse Liver

• Motif significance table
• Sample table
• Mean activities
• All promoters sorted by FOV

• Activity table
• Activity delta table
• Regulatory interactions
• Motifs sorted by significance
• Download the whole report

Gene Symbol	Gene ID	Gene Info
Irf4 Links Ensembl NCBI MGI UniProt	ENSMUSG00000021356.11	interferon regulatory factor 4

Gene	Promoter	Pearson corr. coef.	P-value	Plot
Irf4	mm39_v1_chr13_+_30933209_30933290	0.10	5.7e-01	Click!

Promoter	Log-likelihood	Transcript	Gene	Gene Info
chr11_+_115353290 Show fit	3.40	ENSMUST00000106532.4 ENSMUST00000092445.12 ENSMUST00000153466.2	Slc16a5 Links Ensembl NCBI MGI UniProt Show fit	solute carrier family 16 (monocarboxylic acid transporters), member 5
chr9_-_65330231 Show fit	2.43	ENSMUST00000065894.7	Slc51b Links Ensembl NCBI MGI UniProt Show fit	solute carrier family 51, beta subunit
chr2_-_173060647 Show fit	2.36	ENSMUST00000109116.3 ENSMUST00000029018.14	Zbp1 Links Ensembl NCBI MGI UniProt Show fit	Z-DNA binding protein 1
chr19_-_58443012 Show fit	2.25	ENSMUST00000129100.8 ENSMUST00000123957.2	Gfra1 Links Ensembl NCBI MGI UniProt Show fit	glial cell line derived neurotrophic factor family receptor alpha 1
chr17_-_35081456 Show fit	1.95	ENSMUST00000025229.11 ENSMUST00000176203.9 ENSMUST00000128767.8	Cfb Links Ensembl NCBI MGI UniProt Show fit	complement factor B
chr9_+_44953723 Show fit	1.87	ENSMUST00000034600.5	Mpzl2 Links Ensembl NCBI MGI UniProt Show fit	myelin protein zero-like 2
chr14_+_14475188 Show fit	1.84	ENSMUST00000026315.8	Dnase1l3 Links Ensembl NCBI MGI UniProt Show fit	deoxyribonuclease 1-like 3
chr6_+_82018604 Show fit	1.83	ENSMUST00000042974.15	Eva1a Links Ensembl NCBI MGI UniProt Show fit	eva-1 homolog A (C. elegans)
chr1_-_97904958 Show fit	1.66	ENSMUST00000161567.8	Pam Links Ensembl NCBI MGI UniProt Show fit	peptidylglycine alpha-amidating monooxygenase
chr5_-_104169696 Show fit	1.60	ENSMUST00000119025.2	Hsd17b11 Links Ensembl NCBI MGI UniProt Show fit	hydroxysteroid (17-beta) dehydrogenase 11
chr4_-_19922599 Show fit	1.59	ENSMUST00000029900.6	Atp6v0d2 Links Ensembl NCBI MGI UniProt Show fit	ATPase, H+ transporting, lysosomal V0 subunit D2
chr19_-_58442866 Show fit	1.58	ENSMUST00000169850.8	Gfra1 Links Ensembl NCBI MGI UniProt Show fit	glial cell line derived neurotrophic factor family receptor alpha 1
chr5_-_104169785 Show fit	1.55	ENSMUST00000031251.16	Hsd17b11 Links Ensembl NCBI MGI UniProt Show fit	hydroxysteroid (17-beta) dehydrogenase 11
chr17_+_35481702 Show fit	1.46	ENSMUST00000172785.8	H2-D1 Links Ensembl NCBI MGI UniProt Show fit	histocompatibility 2, D region locus 1
chr4_-_46536088 Show fit	1.44	ENSMUST00000102924.3 ENSMUST00000046897.13	Trim14 Links Ensembl NCBI MGI UniProt Show fit	tripartite motif-containing 14
chr1_-_164763091 Show fit	1.37	ENSMUST00000027860.8	Xcl1 Links Ensembl NCBI MGI UniProt Show fit	chemokine (C motif) ligand 1
chr11_+_48977852 Show fit	1.36	ENSMUST00000046704.7 ENSMUST00000203810.3 ENSMUST00000203149.3	Ifi47 Links Ensembl NCBI MGI UniProt Show fit Olfr56 Links Ensembl NCBI MGI UniProt Show fit	interferon gamma inducible protein 47 olfactory receptor 56
chr19_-_58443830 Show fit	1.34	ENSMUST00000026076.14	Gfra1 Links Ensembl NCBI MGI UniProt Show fit	glial cell line derived neurotrophic factor family receptor alpha 1
chr17_-_35081129 Show fit	1.30	ENSMUST00000154526.8	Cfb Links Ensembl NCBI MGI UniProt Show fit	complement factor B
chr19_-_58443593 Show fit	1.28	ENSMUST00000135730.2 ENSMUST00000152507.8	Gfra1 Links Ensembl NCBI MGI UniProt Show fit	glial cell line derived neurotrophic factor family receptor alpha 1
chr11_+_46701619 Show fit	1.28	ENSMUST00000068877.7	Timd4 Links Ensembl NCBI MGI UniProt Show fit	T cell immunoglobulin and mucin domain containing 4
chr7_-_65020655 Show fit	1.24	ENSMUST00000032729.8	Tjp1 Links Ensembl NCBI MGI UniProt Show fit	tight junction protein 1
chr9_+_14187597 Show fit	1.23	ENSMUST00000208222.2	Sesn3 Links Ensembl NCBI MGI UniProt Show fit	sestrin 3
chr11_+_48977888 Show fit	1.18	ENSMUST00000214804.2	Ifi47 Links Ensembl NCBI MGI UniProt Show fit	interferon gamma inducible protein 47
chr3_+_95434093 Show fit	1.18	ENSMUST00000015667.9 ENSMUST00000116304.3	Ctss Links Ensembl NCBI MGI UniProt Show fit	cathepsin S
chr3_-_148696155 Show fit	1.15	ENSMUST00000196526.5 ENSMUST00000200543.5 ENSMUST00000200154.5	Adgrl2 Links Ensembl NCBI MGI UniProt Show fit	adhesion G protein-coupled receptor L2
chr11_+_78234300 Show fit	1.04	ENSMUST00000002127.14 ENSMUST00000108295.8	Unc119 Links Ensembl NCBI MGI UniProt Show fit	unc-119 lipid binding chaperone
chr9_-_116004386 Show fit	1.04	ENSMUST00000035014.8	Tgfbr2 Links Ensembl NCBI MGI UniProt Show fit	transforming growth factor, beta receptor II
chr1_+_52158599 Show fit	1.02	ENSMUST00000186574.7 ENSMUST00000070968.14 ENSMUST00000191435.7 ENSMUST00000186857.7 ENSMUST00000188681.7	Stat1 Links Ensembl NCBI MGI UniProt Show fit	signal transducer and activator of transcription 1
chr1_-_174749379 Show fit	0.99	ENSMUST00000055294.4	Grem2 Links Ensembl NCBI MGI UniProt Show fit	gremlin 2, DAN family BMP antagonist
chr11_-_101062111 Show fit	0.96	ENSMUST00000164474.8 ENSMUST00000043397.14	Plekhh3 Links Ensembl NCBI MGI UniProt Show fit	pleckstrin homology domain containing, family H (with MyTH4 domain) member 3
chr11_+_43365103 Show fit	0.96	ENSMUST00000173002.8 ENSMUST00000057679.10	C1qtnf2 Links Ensembl NCBI MGI UniProt Show fit	C1q and tumor necrosis factor related protein 2
chr1_+_52158693 Show fit	0.94	ENSMUST00000189347.7	Stat1 Links Ensembl NCBI MGI UniProt Show fit	signal transducer and activator of transcription 1
chr16_-_35759461 Show fit	0.91	ENSMUST00000081933.14 ENSMUST00000114885.3	Dtx3l Links Ensembl NCBI MGI UniProt Show fit	deltex 3-like, E3 ubiquitin ligase
chr14_+_34097474 Show fit	0.90	ENSMUST00000227130.2	Mmrn2 Links Ensembl NCBI MGI UniProt Show fit	multimerin 2
chr2_+_71283620 Show fit	0.89	ENSMUST00000037210.9	Metap1d Links Ensembl NCBI MGI UniProt Show fit	methionyl aminopeptidase type 1D (mitochondrial)
chr5_-_92496730 Show fit	0.85	ENSMUST00000038816.13 ENSMUST00000118006.3	Cxcl10 Links Ensembl NCBI MGI UniProt Show fit	chemokine (C-X-C motif) ligand 10
chr6_-_49191891 Show fit	0.83	ENSMUST00000031838.9	Igf2bp3 Links Ensembl NCBI MGI UniProt Show fit	insulin-like growth factor 2 mRNA binding protein 3
chr8_-_85500010 Show fit	0.83	ENSMUST00000109764.8	Nfix Links Ensembl NCBI MGI UniProt Show fit	nuclear factor I/X
chr1_+_52158721 Show fit	0.82	ENSMUST00000186057.7	Stat1 Links Ensembl NCBI MGI UniProt Show fit	signal transducer and activator of transcription 1
chr6_-_87312743 Show fit	0.78	ENSMUST00000042025.12 ENSMUST00000205033.2	Antxr1 Links Ensembl NCBI MGI UniProt Show fit	anthrax toxin receptor 1
chr7_-_18757461 Show fit	0.78	ENSMUST00000036018.6	Foxa3 Links Ensembl NCBI MGI UniProt Show fit	forkhead box A3
chrX_+_138464065 Show fit	0.77	ENSMUST00000113027.8	Rnf128 Links Ensembl NCBI MGI UniProt Show fit	ring finger protein 128
chr1_+_175459559 Show fit	0.75	ENSMUST00000040250.15	Kmo Links Ensembl NCBI MGI UniProt Show fit	kynurenine 3-monooxygenase (kynurenine 3-hydroxylase)
chr10_+_21758083 Show fit	0.74	ENSMUST00000120509.8	Sgk1 Links Ensembl NCBI MGI UniProt Show fit	serum/glucocorticoid regulated kinase 1
chr17_+_35780977 Show fit	0.74	ENSMUST00000174525.8 ENSMUST00000068291.7	H2-Q10 Links Ensembl NCBI MGI UniProt Show fit	histocompatibility 2, Q region locus 10
chr1_+_175459735 Show fit	0.71	ENSMUST00000097458.4	Kmo Links Ensembl NCBI MGI UniProt Show fit	kynurenine 3-monooxygenase (kynurenine 3-hydroxylase)
chr10_+_69048464 Show fit	0.71	ENSMUST00000020101.12	Rhobtb1 Links Ensembl NCBI MGI UniProt Show fit	Rho-related BTB domain containing 1
chr1_+_16758629 Show fit	0.71	ENSMUST00000026881.11	Ly96 Links Ensembl NCBI MGI UniProt Show fit	lymphocyte antigen 96
chr8_-_85500998 Show fit	0.70	ENSMUST00000109762.8	Nfix Links Ensembl NCBI MGI UniProt Show fit	nuclear factor I/X
chr4_-_136613498 Show fit	0.69	ENSMUST00000046384.9	C1qb Links Ensembl NCBI MGI UniProt Show fit	complement component 1, q subcomponent, beta polypeptide
chr3_+_90444613 Show fit	0.66	ENSMUST00000107335.2	S100a16 Links Ensembl NCBI MGI UniProt Show fit	S100 calcium binding protein A16
chr2_-_127630769 Show fit	0.65	ENSMUST00000028857.14 ENSMUST00000110357.2	Nphp1 Links Ensembl NCBI MGI UniProt Show fit	nephronophthisis 1 (juvenile) homolog (human)
chr6_-_39095144 Show fit	0.64	ENSMUST00000038398.7	Parp12 Links Ensembl NCBI MGI UniProt Show fit	poly (ADP-ribose) polymerase family, member 12
chr14_-_61283911 Show fit	0.64	ENSMUST00000111234.10 ENSMUST00000224371.2	Tnfrsf19 Links Ensembl NCBI MGI UniProt Show fit	tumor necrosis factor receptor superfamily, member 19
chr2_+_22958956 Show fit	0.59	ENSMUST00000226571.2 ENSMUST00000114529.10 ENSMUST00000114526.9 ENSMUST00000228050.2	Acbd5 Links Ensembl NCBI MGI UniProt Show fit	acyl-Coenzyme A binding domain containing 5
chr11_-_77784922 Show fit	0.59	ENSMUST00000017597.5	Pipox Links Ensembl NCBI MGI UniProt Show fit	pipecolic acid oxidase
chr11_+_87457479 Show fit	0.59	ENSMUST00000239011.2	Septin4 Links Ensembl NCBI MGI UniProt Show fit	septin 4
chr7_+_126895463 Show fit	0.59	ENSMUST00000106306.9 ENSMUST00000120857.8	Itgal Links Ensembl NCBI MGI UniProt Show fit	integrin alpha L
chr16_+_35759346 Show fit	0.58	ENSMUST00000023622.13	Parp9 Links Ensembl NCBI MGI UniProt Show fit	poly (ADP-ribose) polymerase family, member 9
chr10_+_128542120 Show fit	0.58	ENSMUST00000054125.9	Pmel Links Ensembl NCBI MGI UniProt Show fit	premelanosome protein
chrX_-_43879055 Show fit	0.57	ENSMUST00000060481.9	Dcaf12l1 Links Ensembl NCBI MGI UniProt Show fit	DDB1 and CUL4 associated factor 12-like 1
chr5_-_92653377 Show fit	0.57	ENSMUST00000031377.9	Scarb2 Links Ensembl NCBI MGI UniProt Show fit	scavenger receptor class B, member 2
chr3_+_90444537 Show fit	0.57	ENSMUST00000098911.10	S100a16 Links Ensembl NCBI MGI UniProt Show fit	S100 calcium binding protein A16
chr1_+_182236728 Show fit	0.57	ENSMUST00000117245.2	Trp53bp2 Links Ensembl NCBI MGI UniProt Show fit	transformation related protein 53 binding protein 2
chr3_+_142202642 Show fit	0.56	ENSMUST00000090127.7	Gbp5 Links Ensembl NCBI MGI UniProt Show fit	guanylate binding protein 5
chr11_-_107361525 Show fit	0.56	ENSMUST00000103064.10	Pitpnc1 Links Ensembl NCBI MGI UniProt Show fit	phosphatidylinositol transfer protein, cytoplasmic 1
chrX_-_43879022 Show fit	0.54	ENSMUST00000115056.2	Dcaf12l1 Links Ensembl NCBI MGI UniProt Show fit	DDB1 and CUL4 associated factor 12-like 1
chr3_-_142101418 Show fit	0.54	ENSMUST00000029941.16 ENSMUST00000058626.9	Pdlim5 Links Ensembl NCBI MGI UniProt Show fit	PDZ and LIM domain 5
chr19_+_56385531 Show fit	0.52	ENSMUST00000026062.10	Casp7 Links Ensembl NCBI MGI UniProt Show fit	caspase 7
chr10_+_69048506 Show fit	0.51	ENSMUST00000167384.8	Rhobtb1 Links Ensembl NCBI MGI UniProt Show fit	Rho-related BTB domain containing 1
chr13_-_19579898 Show fit	0.51	ENSMUST00000197565.3 ENSMUST00000221380.2 ENSMUST00000200323.3 ENSMUST00000199924.2 ENSMUST00000222869.2	Stard3nl Links Ensembl NCBI MGI UniProt Show fit	STARD3 N-terminal like
chr2_+_127967951 Show fit	0.50	ENSMUST00000089634.12 ENSMUST00000019281.14 ENSMUST00000110341.9 ENSMUST00000103211.8 ENSMUST00000103210.2	Bcl2l11 Links Ensembl NCBI MGI UniProt Show fit	BCL2-like 11 (apoptosis facilitator)
chr8_-_106665060 Show fit	0.48	ENSMUST00000034369.10	Psmb10 Links Ensembl NCBI MGI UniProt Show fit	proteasome (prosome, macropain) subunit, beta type 10
chr7_+_126895423 Show fit	0.47	ENSMUST00000117762.8	Itgal Links Ensembl NCBI MGI UniProt Show fit	integrin alpha L
chrM_+_9459 Show fit	0.46	ENSMUST00000082411.1	mt-Nd3 Links Ensembl NCBI MGI UniProt Show fit	mitochondrially encoded NADH dehydrogenase 3
chr11_-_3489228 Show fit	0.46	ENSMUST00000075118.10 ENSMUST00000136243.2 ENSMUST00000020721.15 ENSMUST00000170588.8	Smtn Links Ensembl NCBI MGI UniProt Show fit	smoothelin
chr1_-_155912216 Show fit	0.45	ENSMUST00000027738.14	Tor1aip1 Links Ensembl NCBI MGI UniProt Show fit	torsin A interacting protein 1
chr17_+_23898223 Show fit	0.45	ENSMUST00000024699.4 ENSMUST00000232719.2	Cldn6 Links Ensembl NCBI MGI UniProt Show fit	claudin 6
chr13_-_100753419 Show fit	0.45	ENSMUST00000168772.2 ENSMUST00000163163.9 ENSMUST00000022137.14	Marveld2 Links Ensembl NCBI MGI UniProt Show fit	MARVEL (membrane-associating) domain containing 2
chr14_-_73622638 Show fit	0.44	ENSMUST00000228637.2 ENSMUST00000022704.9	Itm2b Links Ensembl NCBI MGI UniProt Show fit	integral membrane protein 2B
chr5_+_102629240 Show fit	0.44	ENSMUST00000073302.12 ENSMUST00000094559.9	Arhgap24 Links Ensembl NCBI MGI UniProt Show fit	Rho GTPase activating protein 24
chr19_+_34560922 Show fit	0.42	ENSMUST00000102825.4	Ifit3 Links Ensembl NCBI MGI UniProt Show fit	interferon-induced protein with tetratricopeptide repeats 3
chr1_-_155912159 Show fit	0.42	ENSMUST00000097527.10	Tor1aip1 Links Ensembl NCBI MGI UniProt Show fit	torsin A interacting protein 1
chr13_-_19579961 Show fit	0.41	ENSMUST00000039694.13	Stard3nl Links Ensembl NCBI MGI UniProt Show fit	STARD3 N-terminal like
chr8_+_105897300 Show fit	0.41	ENSMUST00000052209.9 ENSMUST00000109392.9 ENSMUST00000109395.8	Cbfb Links Ensembl NCBI MGI UniProt Show fit	core binding factor beta
chr7_+_126895531 Show fit	0.41	ENSMUST00000170971.8	Itgal Links Ensembl NCBI MGI UniProt Show fit	integrin alpha L
chr7_-_89176294 Show fit	0.39	ENSMUST00000207932.2	Prss23 Links Ensembl NCBI MGI UniProt Show fit	protease, serine 23
chr19_+_41017714 Show fit	0.38	ENSMUST00000051806.12 ENSMUST00000112200.3	Dntt Links Ensembl NCBI MGI UniProt Show fit	deoxynucleotidyltransferase, terminal
chr19_+_46611826 Show fit	0.37	ENSMUST00000111855.5	Wbp1l Links Ensembl NCBI MGI UniProt Show fit	WW domain binding protein 1 like
chr9_+_108394761 Show fit	0.37	ENSMUST00000192819.2	Qrich1 Links Ensembl NCBI MGI UniProt Show fit	glutamine-rich 1
chr2_+_22959223 Show fit	0.37	ENSMUST00000114523.10	Acbd5 Links Ensembl NCBI MGI UniProt Show fit	acyl-Coenzyme A binding domain containing 5
chr13_+_38009981 Show fit	0.36	ENSMUST00000110238.10	Rreb1 Links Ensembl NCBI MGI UniProt Show fit	ras responsive element binding protein 1
chr5_-_99391073 Show fit	0.36	ENSMUST00000166484.2	Rasgef1b Links Ensembl NCBI MGI UniProt Show fit	RasGEF domain family, member 1B
chr13_-_100753181 Show fit	0.35	ENSMUST00000225754.2	Marveld2 Links Ensembl NCBI MGI UniProt Show fit	MARVEL (membrane-associating) domain containing 2
chr1_+_61677977 Show fit	0.35	ENSMUST00000075374.10	Pard3b Links Ensembl NCBI MGI UniProt Show fit	par-3 family cell polarity regulator beta
chr3_-_57202301 Show fit	0.34	ENSMUST00000171384.8	Tm4sf1 Links Ensembl NCBI MGI UniProt Show fit	transmembrane 4 superfamily member 1
chr7_-_4448631 Show fit	0.34	ENSMUST00000008579.14	Rdh13 Links Ensembl NCBI MGI UniProt Show fit	retinol dehydrogenase 13 (all-trans and 9-cis)
chrX_+_20714782 Show fit	0.33	ENSMUST00000001155.11 ENSMUST00000122312.8 ENSMUST00000120356.8 ENSMUST00000122850.2	Araf Links Ensembl NCBI MGI UniProt Show fit	Araf proto-oncogene, serine/threonine kinase
chr13_-_23894697 Show fit	0.33	ENSMUST00000091707.13 ENSMUST00000006787.8	Hfe Links Ensembl NCBI MGI UniProt Show fit	homeostatic iron regulator
chr19_-_57185988 Show fit	0.31	ENSMUST00000099294.9	Ablim1 Links Ensembl NCBI MGI UniProt Show fit	actin-binding LIM protein 1
chr13_-_23894828 Show fit	0.31	ENSMUST00000091706.14	Hfe Links Ensembl NCBI MGI UniProt Show fit	homeostatic iron regulator
chr1_-_156766957 Show fit	0.30	ENSMUST00000171292.8 ENSMUST00000063199.13 ENSMUST00000027886.14	Ralgps2 Links Ensembl NCBI MGI UniProt Show fit	Ral GEF with PH domain and SH3 binding motif 2
chr1_+_44158111 Show fit	0.29	ENSMUST00000155917.8	Bivm Links Ensembl NCBI MGI UniProt Show fit	basic, immunoglobulin-like variable motif containing
chrM_+_8603 Show fit	0.29	ENSMUST00000082409.1	mt-Co3 Links Ensembl NCBI MGI UniProt Show fit	mitochondrially encoded cytochrome c oxidase III
chr17_+_34783242 Show fit	0.28	ENSMUST00000015612.14	Notch4 Links Ensembl NCBI MGI UniProt Show fit	notch 4
chr19_-_24202344 Show fit	0.27	ENSMUST00000099558.5 ENSMUST00000232956.2	Tjp2 Links Ensembl NCBI MGI UniProt Show fit	tight junction protein 2
chr11_-_43727071 Show fit	0.26	ENSMUST00000167574.2	Adra1b Links Ensembl NCBI MGI UniProt Show fit	adrenergic receptor, alpha 1b
chr17_+_80597632 Show fit	0.25	ENSMUST00000227729.2 ENSMUST00000061703.10	Morn2 Links Ensembl NCBI MGI UniProt Show fit	MORN repeat containing 2
chr13_-_113182891 Show fit	0.25	ENSMUST00000231962.2 ENSMUST00000022282.6	Gpx8 Links Ensembl NCBI MGI UniProt Show fit	glutathione peroxidase 8 (putative)
chr7_-_5128936 Show fit	0.25	ENSMUST00000147835.4	Rasl2-9 Links Ensembl NCBI MGI UniProt Show fit	RAS-like, family 2, locus 9
chr8_+_46338498 Show fit	0.24	ENSMUST00000034053.7	Pdlim3 Links Ensembl NCBI MGI UniProt Show fit	PDZ and LIM domain 3
chr3_-_102871440 Show fit	0.23	ENSMUST00000058899.13	Nr1h5 Links Ensembl NCBI MGI UniProt Show fit	nuclear receptor subfamily 1, group H, member 5
chr18_+_7869705 Show fit	0.22	ENSMUST00000166062.8 ENSMUST00000169010.8	Wac Links Ensembl NCBI MGI UniProt Show fit	WW domain containing adaptor with coiled-coil
chrX_-_9335525 Show fit	0.22	ENSMUST00000015484.10	Cybb Links Ensembl NCBI MGI UniProt Show fit	cytochrome b-245, beta polypeptide
chr14_+_55815580 Show fit	0.21	ENSMUST00000174484.8	Psme1 Links Ensembl NCBI MGI UniProt Show fit	proteasome (prosome, macropain) activator subunit 1 (PA28 alpha)
chr19_-_57185928 Show fit	0.21	ENSMUST00000111544.8	Ablim1 Links Ensembl NCBI MGI UniProt Show fit	actin-binding LIM protein 1
chr1_-_184464810 Show fit	0.21	ENSMUST00000048572.7	Hlx Links Ensembl NCBI MGI UniProt Show fit	H2.0-like homeobox
chr1_+_16758731 Show fit	0.21	ENSMUST00000190366.2	Ly96 Links Ensembl NCBI MGI UniProt Show fit	lymphocyte antigen 96
chr2_+_22959452 Show fit	0.21	ENSMUST00000155602.4	Acbd5 Links Ensembl NCBI MGI UniProt Show fit	acyl-Coenzyme A binding domain containing 5
chr9_-_107419309 Show fit	0.20	ENSMUST00000195235.6	Cyb561d2 Links Ensembl NCBI MGI UniProt Show fit	cytochrome b-561 domain containing 2
chr19_-_3955230 Show fit	0.20	ENSMUST00000145791.8	Tcirg1 Links Ensembl NCBI MGI UniProt Show fit	T cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 protein A3
chr10_-_53952686 Show fit	0.18	ENSMUST00000220088.2	Man1a Links Ensembl NCBI MGI UniProt Show fit	mannosidase 1, alpha
chr4_-_129132963 Show fit	0.17	ENSMUST00000097873.10	C77080 Links Ensembl NCBI MGI UniProt Show fit	expressed sequence C77080
chr14_+_65504067 Show fit	0.16	ENSMUST00000224629.2	Fbxo16 Links Ensembl NCBI MGI UniProt Show fit	F-box protein 16
chr4_-_107035479 Show fit	0.16	ENSMUST00000058585.14	Tceanc2 Links Ensembl NCBI MGI UniProt Show fit	transcription elongation factor A (SII) N-terminal and central domain containing 2
chr14_+_55815999 Show fit	0.14	ENSMUST00000172738.2 ENSMUST00000089619.13	Psme1 Links Ensembl NCBI MGI UniProt Show fit	proteasome (prosome, macropain) activator subunit 1 (PA28 alpha)
chr10_-_12424623 Show fit	0.14	ENSMUST00000219003.2	Utrn Links Ensembl NCBI MGI UniProt Show fit	utrophin
chr10_+_56255184 Show fit	0.14	ENSMUST00000220069.2	Gja1 Links Ensembl NCBI MGI UniProt Show fit	gap junction protein, alpha 1
chr1_+_57884693 Show fit	0.14	ENSMUST00000169772.3	Spats2l Links Ensembl NCBI MGI UniProt Show fit	spermatogenesis associated, serine-rich 2-like
chr18_+_37840092 Show fit	0.14	ENSMUST00000195823.2	Pcdhga6 Links Ensembl NCBI MGI UniProt Show fit	protocadherin gamma subfamily A, 6
chr14_+_55815879 Show fit	0.14	ENSMUST00000174563.8	Psme1 Links Ensembl NCBI MGI UniProt Show fit	proteasome (prosome, macropain) activator subunit 1 (PA28 alpha)
chr10_+_18283405 Show fit	0.13	ENSMUST00000037341.14	Nhsl1 Links Ensembl NCBI MGI UniProt Show fit	NHS-like 1
chr2_+_38401826 Show fit	0.13	ENSMUST00000112895.8	Nek6 Links Ensembl NCBI MGI UniProt Show fit	NIMA (never in mitosis gene a)-related expressed kinase 6
chr6_-_70313491 Show fit	0.13	ENSMUST00000103388.4	Igkv6-20 Links Ensembl NCBI MGI UniProt Show fit	immunoglobulin kappa variable 6-20
chr19_-_57185808 Show fit	0.12	ENSMUST00000111546.8	Ablim1 Links Ensembl NCBI MGI UniProt Show fit	actin-binding LIM protein 1
chr3_+_89328926 Show fit	0.12	ENSMUST00000094378.10 ENSMUST00000137793.2	Shc1 Links Ensembl NCBI MGI UniProt Show fit	src homology 2 domain-containing transforming protein C1
chr6_-_87312681 Show fit	0.12	ENSMUST00000204805.3	Antxr1 Links Ensembl NCBI MGI UniProt Show fit	anthrax toxin receptor 1
chr14_+_55815817 Show fit	0.11	ENSMUST00000174259.8	Psme1 Links Ensembl NCBI MGI UniProt Show fit	proteasome (prosome, macropain) activator subunit 1 (PA28 alpha)
chr11_+_119283887 Show fit	0.11	ENSMUST00000093902.12 ENSMUST00000131035.10	Rnf213 Links Ensembl NCBI MGI UniProt Show fit	ring finger protein 213
chr13_-_30170031 Show fit	0.11	ENSMUST00000102948.11	E2f3 Links Ensembl NCBI MGI UniProt Show fit	E2F transcription factor 3
chr10_+_94411119 Show fit	0.10	ENSMUST00000121471.8	Tmcc3 Links Ensembl NCBI MGI UniProt Show fit	transmembrane and coiled coil domains 3
chr5_+_102629365 Show fit	0.10	ENSMUST00000112854.8	Arhgap24 Links Ensembl NCBI MGI UniProt Show fit	Rho GTPase activating protein 24
chr5_+_24598633 Show fit	0.10	ENSMUST00000138168.3 ENSMUST00000115077.8	Abcb8 Links Ensembl NCBI MGI UniProt Show fit	ATP-binding cassette, sub-family B (MDR/TAP), member 8
chr8_-_46577183 Show fit	0.09	ENSMUST00000170416.8	Snx25 Links Ensembl NCBI MGI UniProt Show fit	sorting nexin 25
chr13_-_100689212 Show fit	0.09	ENSMUST00000022140.12	Ocln Links Ensembl NCBI MGI UniProt Show fit	occludin
chr2_+_112114906 Show fit	0.08	ENSMUST00000053666.8	Slc12a6 Links Ensembl NCBI MGI UniProt Show fit	solute carrier family 12, member 6
chr9_-_35179042 Show fit	0.08	ENSMUST00000217306.2 ENSMUST00000125087.2 ENSMUST00000121564.8 ENSMUST00000063782.12 ENSMUST00000059057.14	Fam118b Links Ensembl NCBI MGI UniProt Show fit	family with sequence similarity 118, member B
chrX_+_93679671 Show fit	0.07	ENSMUST00000096368.4	Gspt2 Links Ensembl NCBI MGI UniProt Show fit	G1 to S phase transition 2
chr10_+_82696135 Show fit	0.07	ENSMUST00000219442.3	Txnrd1 Links Ensembl NCBI MGI UniProt Show fit	thioredoxin reductase 1
chr15_+_102391614 Show fit	0.06	ENSMUST00000229432.2	Pcbp2 Links Ensembl NCBI MGI UniProt Show fit	poly(rC) binding protein 2
chrX_+_135608725 Show fit	0.06	ENSMUST00000055104.6	Tceal1 Links Ensembl NCBI MGI UniProt Show fit	transcription elongation factor A (SII)-like 1
chr1_-_163141278 Show fit	0.06	ENSMUST00000027878.14	Prrx1 Links Ensembl NCBI MGI UniProt Show fit	paired related homeobox 1
chr11_+_48977495 Show fit	0.06	ENSMUST00000152914.2	Ifi47 Links Ensembl NCBI MGI UniProt Show fit	interferon gamma inducible protein 47
chr19_+_34585322 Show fit	0.06	ENSMUST00000076249.6	Ifit3b Links Ensembl NCBI MGI UniProt Show fit	interferon-induced protein with tetratricopeptide repeats 3B
chr12_-_113542610 Show fit	0.05	ENSMUST00000195468.6 ENSMUST00000103442.3	Ighv5-2 Links Ensembl NCBI MGI UniProt Show fit	immunoglobulin heavy variable 5-2
chr1_+_57445487 Show fit	0.04	ENSMUST00000027114.6	Maip1 Links Ensembl NCBI MGI UniProt Show fit	matrix AAA peptidase interacting protein 1
chr12_+_108601963 Show fit	0.04	ENSMUST00000223109.2	Evl Links Ensembl NCBI MGI UniProt Show fit	Ena-vasodilator stimulated phosphoprotein
chr16_-_43484494 Show fit	0.04	ENSMUST00000096065.6	Tigit Links Ensembl NCBI MGI UniProt Show fit	T cell immunoreceptor with Ig and ITIM domains
chr15_-_66432938 Show fit	0.04	ENSMUST00000048372.7	Tmem71 Links Ensembl NCBI MGI UniProt Show fit	transmembrane protein 71
chr2_+_38401655 Show fit	0.04	ENSMUST00000054234.10 ENSMUST00000112902.8	Nek6 Links Ensembl NCBI MGI UniProt Show fit	NIMA (never in mitosis gene a)-related expressed kinase 6
chr11_+_87938626 Show fit	0.04	ENSMUST00000107920.10	Srsf1 Links Ensembl NCBI MGI UniProt Show fit	serine and arginine-rich splicing factor 1
chr3_+_152052102 Show fit	0.03	ENSMUST00000117492.9 ENSMUST00000026507.13 ENSMUST00000197748.5	Usp33 Links Ensembl NCBI MGI UniProt Show fit	ubiquitin specific peptidase 33
chr8_+_46338557 Show fit	0.02	ENSMUST00000210422.2	Pdlim3 Links Ensembl NCBI MGI UniProt Show fit	PDZ and LIM domain 3
chr14_-_78970160 Show fit	0.02	ENSMUST00000226342.3	Dgkh Links Ensembl NCBI MGI UniProt Show fit	diacylglycerol kinase, eta
chr7_-_140846328 Show fit	0.02	ENSMUST00000106023.8 ENSMUST00000097952.9 ENSMUST00000026571.11	Irf7 Links Ensembl NCBI MGI UniProt Show fit	interferon regulatory factor 7
chrX_-_100266032 Show fit	0.00	ENSMUST00000120389.8 ENSMUST00000156473.8 ENSMUST00000077876.4	Snx12 Links Ensembl NCBI MGI UniProt Show fit	sorting nexin 12
chr14_+_65504151 Show fit	0.00	ENSMUST00000169656.3 ENSMUST00000226005.2	Fbxo16 Links Ensembl NCBI MGI UniProt Show fit	F-box protein 16
chr18_+_37637317 Show fit	0.00	ENSMUST00000052179.8	Pcdhb20 Links Ensembl NCBI MGI UniProt Show fit	protocadherin beta 20

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Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.9	2.8	GO:0034240	negative regulation of macrophage fusion(GO:0034240)
0.8	3.2	GO:0006710	androgen catabolic process(GO:0006710)
0.6	2.4	GO:2000563	positive regulation of CD4-positive, alpha-beta T cell proliferation(GO:2000563)
0.4	1.2	GO:0034769	basement membrane disassembly(GO:0034769)
0.3	1.0	GO:0060300	regulation of cytokine activity(GO:0060300)
0.3	1.5	GO:0002485	antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway(GO:0002484) antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent(GO:0002485)
0.3	1.0	GO:2001287	negative regulation of caveolin-mediated endocytosis(GO:2001287)
0.2	1.5	GO:0019805	quinolinate biosynthetic process(GO:0019805)
0.2	0.7	GO:1903348	positive regulation of bicellular tight junction assembly(GO:1903348)
0.2	0.9	GO:1901740	negative regulation of myoblast fusion(GO:1901740)
0.2	0.6	GO:1900390	regulation of antigen processing and presentation of peptide antigen via MHC class I(GO:0002589) negative regulation of antigen processing and presentation of peptide antigen via MHC class I(GO:0002590) regulation of T cell antigen processing and presentation(GO:0002625) positive regulation of iron ion transport(GO:0034758) positive regulation of iron ion transmembrane transport(GO:0034761) regulation of iron ion import(GO:1900390) regulation of ferrous iron import into cell(GO:1903989) positive regulation of ferrous iron import into cell(GO:1903991) regulation of ferrous iron binding(GO:1904432) positive regulation of ferrous iron binding(GO:1904434) regulation of transferrin receptor binding(GO:1904435) positive regulation of transferrin receptor binding(GO:1904437) regulation of ferrous iron import across plasma membrane(GO:1904438) positive regulation of ferrous iron import across plasma membrane(GO:1904440)
0.2	1.7	GO:0031179	peptide modification(GO:0031179)
0.2	0.6	GO:0006553	lysine metabolic process(GO:0006553)
0.2	0.8	GO:0070368	positive regulation of hepatocyte differentiation(GO:0070368)
0.2	3.3	GO:0006957	complement activation, alternative pathway(GO:0006957)
0.2	2.4	GO:0070863	positive regulation of protein glycosylation(GO:0060050) positive regulation of protein exit from endoplasmic reticulum(GO:0070863)
0.2	1.5	GO:0002291	T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell(GO:0002291)
0.1	0.9	GO:1903054	negative regulation of extracellular matrix organization(GO:1903054)
0.1	1.2	GO:0038203	TORC2 signaling(GO:0038203)
0.1	0.9	GO:0032497	detection of lipopolysaccharide(GO:0032497)
0.1	2.4	GO:0060340	positive regulation of type I interferon-mediated signaling pathway(GO:0060340)
0.1	1.2	GO:0030242	pexophagy(GO:0030242)
0.1	0.5	GO:0072734	response to staurosporine(GO:0072733) cellular response to staurosporine(GO:0072734)
0.1	0.5	GO:0052151	positive regulation by symbiont of host apoptotic process(GO:0052151) positive regulation of apoptotic process by virus(GO:0060139)
0.1	1.5	GO:0090557	establishment of endothelial intestinal barrier(GO:0090557)
0.1	0.3	GO:0001982	baroreceptor response to decreased systemic arterial blood pressure(GO:0001982)
0.1	1.8	GO:0006309	apoptotic DNA fragmentation(GO:0006309)
0.1	0.9	GO:0071763	nuclear membrane organization(GO:0071763)
0.1	1.5	GO:0021684	cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.1	0.6	GO:1900227	positive regulation of NLRP3 inflammasome complex assembly(GO:1900227)
0.1	1.8	GO:0007035	vacuolar acidification(GO:0007035)
0.1	0.9	GO:0030948	negative regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030948)
0.1	2.6	GO:0035458	cellular response to interferon-beta(GO:0035458)
0.1	0.4	GO:0042985	negative regulation of amyloid precursor protein biosynthetic process(GO:0042985)
0.1	0.5	GO:0035021	negative regulation of Rac protein signal transduction(GO:0035021)
0.1	0.4	GO:1903691	positive regulation of wound healing, spreading of epidermal cells(GO:1903691)
0.0	1.4	GO:0032897	negative regulation of viral transcription(GO:0032897)
0.0	0.1	GO:0003294	atrial ventricular junction remodeling(GO:0003294) regulation of cell communication by chemical coupling(GO:0010645) positive regulation of cell communication by chemical coupling(GO:0010652)
0.0	0.7	GO:0043402	glucocorticoid mediated signaling pathway(GO:0043402)
0.0	0.2	GO:0071894	histone H2B conserved C-terminal lysine ubiquitination(GO:0071894)
0.0	0.3	GO:0009644	response to high light intensity(GO:0009644)
0.0	0.2	GO:0045629	negative regulation of T-helper 2 cell differentiation(GO:0045629)
0.0	0.6	GO:0060330	regulation of response to interferon-gamma(GO:0060330)
0.0	1.0	GO:0046321	positive regulation of fatty acid oxidation(GO:0046321)
0.0	0.3	GO:1903847	regulation of aorta morphogenesis(GO:1903847) positive regulation of aorta morphogenesis(GO:1903849)
0.0	0.6	GO:0048023	positive regulation of melanin biosynthetic process(GO:0048023) positive regulation of secondary metabolite biosynthetic process(GO:1900378)
0.0	0.6	GO:1900119	positive regulation of execution phase of apoptosis(GO:1900119)
0.0	0.6	GO:0006622	protein targeting to lysosome(GO:0006622)
0.0	0.2	GO:0097411	hypoxia-inducible factor-1alpha signaling pathway(GO:0097411)
0.0	0.7	GO:0002474	antigen processing and presentation of peptide antigen via MHC class I(GO:0002474)
0.0	0.9	GO:0010390	histone monoubiquitination(GO:0010390)
0.0	0.1	GO:0002184	cytoplasmic translational termination(GO:0002184)
0.0	0.1	GO:0097475	motor neuron migration(GO:0097475)
0.0	5.8	GO:0050731	positive regulation of peptidyl-tyrosine phosphorylation(GO:0050731)
0.0	0.2	GO:0032485	regulation of Ral protein signal transduction(GO:0032485)
0.0	0.8	GO:0042036	negative regulation of cytokine biosynthetic process(GO:0042036)
0.0	0.1	GO:0071477	hypotonic salinity response(GO:0042539) cellular hypotonic salinity response(GO:0071477)
0.0	0.1	GO:0007527	adult somatic muscle development(GO:0007527)
0.0	0.1	GO:1990839	response to endothelin(GO:1990839)
0.0	0.6	GO:0019884	antigen processing and presentation of exogenous antigen(GO:0019884)
0.0	1.9	GO:0033077	T cell differentiation in thymus(GO:0033077) thymocyte aggregation(GO:0071594)
0.0	0.5	GO:0071385	cellular response to glucocorticoid stimulus(GO:0071385)
0.0	0.1	GO:0030576	Cajal body organization(GO:0030576)
0.0	0.2	GO:0033750	ribosomal subunit export from nucleus(GO:0000054) ribosome localization(GO:0033750) establishment of ribosome localization(GO:0033753)
0.0	0.1	GO:0070345	negative regulation of fat cell proliferation(GO:0070345)
0.0	0.7	GO:0070830	bicellular tight junction assembly(GO:0070830)
0.0	0.1	GO:2000051	negative regulation of non-canonical Wnt signaling pathway(GO:2000051)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	1.5	GO:0034687	integrin alphaL-beta2 complex(GO:0034687)
0.2	2.2	GO:0042612	MHC class I protein complex(GO:0042612)
0.1	0.9	GO:0046696	lipopolysaccharide receptor complex(GO:0046696)
0.1	0.6	GO:0043202	lysosomal lumen(GO:0043202)
0.1	1.2	GO:0061700	GATOR2 complex(GO:0061700)
0.1	1.6	GO:0033179	proton-transporting V-type ATPase, V0 domain(GO:0033179)
0.1	0.6	GO:0008537	proteasome activator complex(GO:0008537)
0.1	0.8	GO:0061689	paranodal junction(GO:0033010) tricellular tight junction(GO:0061689)
0.1	0.5	GO:1990111	spermatoproteasome complex(GO:1990111)
0.1	0.6	GO:1990357	terminal web(GO:1990357)
0.1	1.2	GO:0046581	intercellular canaliculus(GO:0046581)
0.1	0.6	GO:0032585	multivesicular body membrane(GO:0032585)
0.1	0.9	GO:0031258	lamellipodium membrane(GO:0031258)
0.0	0.9	GO:0044232	organelle membrane contact site(GO:0044232)
0.0	0.1	GO:0070435	Shc-EGFR complex(GO:0070435)
0.0	3.2	GO:0005811	lipid particle(GO:0005811)
0.0	6.3	GO:0031225	anchored component of membrane(GO:0031225)
0.0	0.1	GO:0018444	translation release factor complex(GO:0018444)
0.0	1.0	GO:0051233	spindle midzone(GO:0051233)
0.0	1.7	GO:0030667	secretory granule membrane(GO:0030667)
0.0	0.7	GO:0097546	ciliary base(GO:0097546)
0.0	0.5	GO:0005868	cytoplasmic dynein complex(GO:0005868)
0.0	1.6	GO:0005581	collagen trimer(GO:0005581)
0.0	0.2	GO:0043020	NADPH oxidase complex(GO:0043020)
0.0	0.2	GO:0016471	vacuolar proton-transporting V-type ATPase complex(GO:0016471)
0.0	0.4	GO:0005921	gap junction(GO:0005921)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.8	2.4	GO:0003692	left-handed Z-DNA binding(GO:0003692)
0.4	1.7	GO:0016842	amidine-lyase activity(GO:0016842)
0.3	1.0	GO:0005026	transforming growth factor beta receptor activity, type II(GO:0005026)
0.3	1.5	GO:0030369	ICAM-3 receptor activity(GO:0030369)
0.2	2.8	GO:0031730	CCR5 chemokine receptor binding(GO:0031730)
0.2	3.2	GO:0004303	estradiol 17-beta-dehydrogenase activity(GO:0004303)
0.2	2.8	GO:0030881	beta-2-microglobulin binding(GO:0030881)
0.2	0.9	GO:0001875	lipopolysaccharide receptor activity(GO:0001875)
0.1	0.9	GO:0048248	CXCR3 chemokine receptor binding(GO:0048248)
0.1	1.5	GO:0016174	NAD(P)H oxidase activity(GO:0016174)
0.1	1.4	GO:0071253	connexin binding(GO:0071253)
0.1	1.0	GO:0036122	BMP binding(GO:0036122)
0.1	0.6	GO:0016647	oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor(GO:0016647)
0.1	0.7	GO:0043423	3-phosphoinositide-dependent protein kinase binding(GO:0043423)
0.1	1.6	GO:0008553	hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.1	0.3	GO:0004937	alpha1-adrenergic receptor activity(GO:0004937)
0.1	0.6	GO:0061133	endopeptidase activator activity(GO:0061133)
0.1	3.4	GO:0008028	monocarboxylic acid transmembrane transporter activity(GO:0008028)
0.0	0.6	GO:0008526	phosphatidylinositol transporter activity(GO:0008526)
0.0	1.2	GO:0001968	fibronectin binding(GO:0001968)
0.0	6.6	GO:0005178	integrin binding(GO:0005178)
0.0	0.5	GO:0097200	cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.0	1.1	GO:0003950	NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0	1.1	GO:0008009	chemokine activity(GO:0008009)
0.0	1.0	GO:0000062	fatty-acyl-CoA binding(GO:0000062)
0.0	0.9	GO:0005521	lamin binding(GO:0005521)
0.0	1.8	GO:0004520	endodeoxyribonuclease activity(GO:0004520)
0.0	0.8	GO:0048027	mRNA 5'-UTR binding(GO:0048027)
0.0	0.1	GO:0048408	epidermal growth factor binding(GO:0048408)
0.0	1.3	GO:0001786	phosphatidylserine binding(GO:0001786)
0.0	0.5	GO:0098641	cadherin binding involved in cell-cell adhesion(GO:0098641)
0.0	0.1	GO:0035827	rubidium ion transmembrane transporter activity(GO:0035827)
0.0	0.2	GO:0016175	superoxide-generating NADPH oxidase activity(GO:0016175)
0.0	0.5	GO:0070003	threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0	0.5	GO:0001618	virus receptor activity(GO:0001618)
0.0	3.6	GO:0004252	serine-type endopeptidase activity(GO:0004252)
0.0	0.5	GO:0050136	NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0	0.5	GO:0070840	dynein complex binding(GO:0070840)
0.0	0.2	GO:0004571	mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.0	0.9	GO:0015485	cholesterol binding(GO:0015485)
0.0	0.6	GO:0051059	NF-kappaB binding(GO:0051059)
0.0	4.7	GO:0003924	GTPase activity(GO:0003924)
0.0	0.2	GO:0036442	hydrogen-exporting ATPase activity(GO:0036442) proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.0	0.3	GO:0004709	MAP kinase kinase kinase activity(GO:0004709)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	2.8	ST TYPE I INTERFERON PATHWAY	Type I Interferon (alpha/beta IFN) Pathway
0.1	3.1	ST G ALPHA S PATHWAY	G alpha s Pathway
0.1	6.6	PID RET PATHWAY	Signaling events regulated by Ret tyrosine kinase
0.0	1.5	PID INTEGRIN2 PATHWAY	Beta2 integrin cell surface interactions
0.0	0.9	PID ANTHRAX PATHWAY	Cellular roles of Anthrax toxin
0.0	1.0	PID ALK1 PATHWAY	ALK1 signaling events
0.0	1.2	PID NEPHRIN NEPH1 PATHWAY	Nephrin/Neph1 signaling in the kidney podocyte
0.0	0.9	PID TOLL ENDOGENOUS PATHWAY	Endogenous TLR signaling
0.0	0.9	PID CXCR3 PATHWAY	CXCR3-mediated signaling events
0.0	1.2	PID FOXO PATHWAY	FoxO family signaling
0.0	0.4	PID DNA PK PATHWAY	DNA-PK pathway in nonhomologous end joining
0.0	0.5	SA CASPASE CASCADE	Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0	0.3	ST ERK1 ERK2 MAPK PATHWAY	ERK1/ERK2 MAPK Pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.4	1.2	REACTOME ENDOSOMAL VACUOLAR PATHWAY	Genes involved in Endosomal/Vacuolar pathway
0.2	3.9	REACTOME INITIAL TRIGGERING OF COMPLEMENT	Genes involved in Initial triggering of complement
0.2	0.9	REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1	Genes involved in IKK complex recruitment mediated by RIP1
0.2	2.8	REACTOME IL 6 SIGNALING	Genes involved in Interleukin-6 signaling
0.1	6.5	REACTOME NCAM1 INTERACTIONS	Genes involved in NCAM1 interactions
0.1	2.4	REACTOME RIP MEDIATED NFKB ACTIVATION VIA DAI	Genes involved in RIP-mediated NFkB activation via DAI
0.1	0.9	REACTOME TRYPTOPHAN CATABOLISM	Genes involved in Tryptophan catabolism
0.1	1.4	REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS	Genes involved in Apoptotic cleavage of cell adhesion proteins
0.1	1.8	REACTOME INSULIN RECEPTOR RECYCLING	Genes involved in Insulin receptor recycling
0.0	2.2	REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES	Genes involved in Chemokine receptors bind chemokines
0.0	1.0	REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION	Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0	1.0	REACTOME SIGNALING BY BMP	Genes involved in Signaling by BMP
0.0	1.5	REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL	Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0	0.3	REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR	Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.0	0.6	REACTOME DCC MEDIATED ATTRACTIVE SIGNALING	Genes involved in DCC mediated attractive signaling
0.0	1.1	REACTOME AUTODEGRADATION OF THE E3 UBIQUITIN LIGASE COP1	Genes involved in Autodegradation of the E3 ubiquitin ligase COP1
0.0	0.5	REACTOME ACTIVATION OF BH3 ONLY PROTEINS	Genes involved in Activation of BH3-only proteins
0.0	0.4	REACTOME AMYLOIDS	Genes involved in Amyloids
0.0	0.5	REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS	Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0	0.2	REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS	Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis