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GSE58827: Dynamics of the Mouse Liver

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Results for Isl2

Z-value: 0.46

Motif logo

Transcription factors associated with Isl2

Gene Symbol Gene ID Gene Info
ENSMUSG00000032318.13 insulin related protein 2 (islet 2)

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Isl2mm39_v1_chr9_+_55448432_55448493-0.382.2e-02Click!

Activity profile of Isl2 motif

Sorted Z-values of Isl2 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr8_+_114860375 3.49 ENSMUST00000147605.8
ENSMUST00000134593.2
nudix (nucleoside diphosphate linked moiety X)-type motif 7
chr6_-_41012435 3.32 ENSMUST00000031931.6
RIKEN cDNA 2210010C04 gene
chr17_-_28779678 3.14 ENSMUST00000114785.3
ENSMUST00000025062.5
colipase, pancreatic
chr8_+_114860342 2.95 ENSMUST00000109109.8
nudix (nucleoside diphosphate linked moiety X)-type motif 7
chr8_+_114860297 2.69 ENSMUST00000073521.12
ENSMUST00000066514.13
nudix (nucleoside diphosphate linked moiety X)-type motif 7
chr19_-_39637489 2.48 ENSMUST00000067328.7
cytochrome P450, family 2, subfamily c, polypeptide 67
chr19_-_8109346 2.03 ENSMUST00000065651.5
solute carrier family 22, member 28
chr19_+_12673147 2.00 ENSMUST00000025598.10
ENSMUST00000138545.8
ENSMUST00000154822.2
kidney expressed gene 1
chr3_-_67422821 1.98 ENSMUST00000054825.5
retinoic acid receptor responder (tazarotene induced) 1
chr1_+_88139678 1.93 ENSMUST00000073049.7
UDP glucuronosyltransferase 1 family, polypeptide A1
chr1_-_139786421 1.56 ENSMUST00000194186.6
ENSMUST00000094489.5
ENSMUST00000239380.2
complement factor H-related 2
chr17_-_56312555 1.46 ENSMUST00000043785.8
signal transducing adaptor family member 2
chr6_-_136899167 1.32 ENSMUST00000032343.7
endoplasmic reticulum protein 27
chr19_-_39801188 1.27 ENSMUST00000162507.2
ENSMUST00000160476.9
ENSMUST00000239028.2
cytochrome P450, family 2, subfamily c, polypeptide 40
chr1_-_121260298 1.17 ENSMUST00000071064.13
insulin induced gene 2
chr19_-_39875192 1.13 ENSMUST00000168838.3
cytochrome P450, family 2, subfamily c, polypeptide 69
chr9_+_118931532 1.13 ENSMUST00000165231.8
ENSMUST00000140326.8
deleted in lung and esophageal cancer 1
chr19_+_37425180 1.12 ENSMUST00000128184.3
hematopoietically expressed homeobox
chr1_+_87983099 1.11 ENSMUST00000138182.8
ENSMUST00000113142.10
UDP glycosyltransferase 1 family, polypeptide A10
chr1_+_87998487 1.09 ENSMUST00000073772.5
UDP glucuronosyltransferase 1 family, polypeptide A9
chr10_+_23727325 1.08 ENSMUST00000020190.8
vanin 3
chr7_-_100306160 1.05 ENSMUST00000107046.8
ENSMUST00000107045.9
ENSMUST00000139708.9
pleckstrin homology domain containing, family B (evectins) member 1
chr4_+_43493344 0.89 ENSMUST00000030181.12
ENSMUST00000107922.3
coiled-coil domain containing 107
chr17_+_85335775 0.87 ENSMUST00000024944.9
solute carrier family 3, member 1
chr1_-_121260274 0.83 ENSMUST00000161068.2
insulin induced gene 2
chr5_+_87148697 0.81 ENSMUST00000031186.9
UDP glucuronosyltransferase 2 family, polypeptide B35
chr1_+_87983189 0.80 ENSMUST00000173325.2
UDP glycosyltransferase 1 family, polypeptide A10
chr1_+_180878797 0.76 ENSMUST00000036819.7
RIKEN cDNA 9130409I23 gene
chrM_+_10167 0.71 ENSMUST00000082414.1
mitochondrially encoded NADH dehydrogenase 4
chr3_+_89366425 0.71 ENSMUST00000029564.12
phosphomevalonate kinase
chr3_-_75177378 0.71 ENSMUST00000039047.5
serine (or cysteine) peptidase inhibitor, clade I, member 2
chr5_+_90708962 0.70 ENSMUST00000094615.8
ENSMUST00000200765.2
albumin superfamily member 1
chrX_+_100427331 0.68 ENSMUST00000119190.2
gap junction protein, beta 1
chr13_-_12476313 0.67 ENSMUST00000143693.8
ENSMUST00000144283.2
ENSMUST00000099820.10
ENSMUST00000135166.8
lectin, galactose binding, soluble 8
chr9_-_15212849 0.65 ENSMUST00000034414.10
RIKEN cDNA 4931406C07 gene
chr9_+_119170486 0.65 ENSMUST00000175743.8
ENSMUST00000176397.8
acetyl-Coenzyme A acyltransferase 1A
chr7_+_86895996 0.63 ENSMUST00000068829.13
NADPH oxidase 4
chr7_-_12829100 0.61 ENSMUST00000209822.3
ENSMUST00000235753.2
vomeronasal 1 receptor 85
chr4_-_119217079 0.61 ENSMUST00000143494.3
ENSMUST00000154606.9
coiled-coil domain containing 30
chr11_+_109434519 0.60 ENSMUST00000106696.2
arylsulfatase G
chr11_+_5470652 0.58 ENSMUST00000063084.16
X-box binding protein 1
chr9_+_108167628 0.57 ENSMUST00000035227.8
nicolin 1
chrM_+_9459 0.56 ENSMUST00000082411.1
mitochondrially encoded NADH dehydrogenase 3
chr6_-_83098255 0.56 ENSMUST00000205023.2
ENSMUST00000146328.4
ENSMUST00000151393.7
ENSMUST00000032111.11
ENSMUST00000113936.10
WW domain binding protein 1
chr9_+_107765320 0.55 ENSMUST00000191906.6
ENSMUST00000035202.4
MON1 homolog A, secretory traffciking associated
chr11_-_101169753 0.52 ENSMUST00000168089.2
ENSMUST00000017332.4
cytochrome C oxidase assembly factor 3
chr6_-_115569504 0.47 ENSMUST00000112957.2
makorin, ring finger protein 2, opposite strand
chr6_+_124281607 0.46 ENSMUST00000032234.5
ENSMUST00000112541.8
CD163 antigen
chrM_+_3906 0.40 ENSMUST00000082396.1
mitochondrially encoded NADH dehydrogenase 2
chr8_+_127898139 0.39 ENSMUST00000238870.2
par-3 family cell polarity regulator
chr17_+_79919267 0.38 ENSMUST00000223924.2
regulator of microtubule dynamics 2
chrM_+_14138 0.38 ENSMUST00000082421.1
mitochondrially encoded cytochrome b
chr4_+_22357543 0.38 ENSMUST00000039234.10
F-box and leucine-rich repeat protein 4
chr12_-_84664001 0.37 ENSMUST00000221070.2
ENSMUST00000021666.6
ENSMUST00000223107.2
ATP-binding cassette, sub-family D (ALD), member 4
chrM_+_9870 0.37 ENSMUST00000084013.1
mitochondrially encoded NADH dehydrogenase 4L
chr6_+_78347636 0.37 ENSMUST00000204873.3
regenerating islet-derived 3 beta
chr5_-_3697806 0.35 ENSMUST00000119783.2
ENSMUST00000007559.15
GATA zinc finger domain containing 1
chr11_+_94218810 0.35 ENSMUST00000107818.9
ENSMUST00000051221.13
ankyrin repeat domain 40
chr11_-_49004584 0.35 ENSMUST00000203007.2
olfactory receptor 1396
chr3_-_96104886 0.34 ENSMUST00000016087.4
bolA-like 1 (E. coli)
chr11_+_94219046 0.34 ENSMUST00000021227.6
ankyrin repeat domain 40
chr19_+_45064539 0.33 ENSMUST00000026234.5
Kazal-type serine peptidase inhibitor domain 1
chr15_+_100251030 0.33 ENSMUST00000075675.7
ENSMUST00000088142.6
ENSMUST00000176287.2
methyltransferase hypoxia inducible domain containing 1
methyltransferase like 7A2
chr2_+_69727563 0.33 ENSMUST00000055758.16
ENSMUST00000112251.9
ubiquitin protein ligase E3 component n-recognin 3
chr5_-_118382926 0.33 ENSMUST00000117177.8
ENSMUST00000133372.2
ENSMUST00000154786.8
ENSMUST00000121369.8
ring finger protein, transmembrane 2
chr2_+_68966125 0.32 ENSMUST00000041865.8
nitric oxide synthase trafficker
chr12_+_10440755 0.32 ENSMUST00000020947.7
retinol dehydrogenase 14 (all-trans and 9-cis)
chr9_-_51240201 0.32 ENSMUST00000039959.11
ENSMUST00000238450.3
RIKEN cDNA 1810046K07 gene
chr9_+_107440484 0.32 ENSMUST00000193418.2
tumor suppressor 2, mitochondrial calcium regulator
chr1_-_57008986 0.32 ENSMUST00000176759.2
ENSMUST00000177424.2
special AT-rich sequence binding protein 2
chr13_-_43634695 0.31 ENSMUST00000144326.4
RAN binding protein 9
chr11_+_69729340 0.31 ENSMUST00000133967.8
ENSMUST00000094065.5
transmembrane protein 256
chr15_+_99192968 0.31 ENSMUST00000128352.8
ENSMUST00000145482.8
pre-mRNA processing factor 40B
chr6_+_40619913 0.30 ENSMUST00000238599.2
maltase-glucoamylase
chr9_+_21634779 0.30 ENSMUST00000034713.9
low density lipoprotein receptor
chr3_-_49711706 0.30 ENSMUST00000191794.2
protocadherin 18
chr16_-_48592319 0.30 ENSMUST00000239408.2
T cell receptor associated transmembrane adaptor 1
chrX_-_103024847 0.30 ENSMUST00000121153.8
ENSMUST00000070705.6
ring finger protein, LIM domain interacting
chr13_+_74554509 0.29 ENSMUST00000222435.2
ferritin light polypeptide 1, pseudogene 1
chr4_+_105014536 0.29 ENSMUST00000064139.8
phospholipid phosphatase 3
chr19_-_7943365 0.28 ENSMUST00000182102.8
ENSMUST00000075619.5
solute carrier family 22, member 27
chr11_+_58062467 0.28 ENSMUST00000020820.2
mitochondrial ribosomal protein L22
chr9_+_81745723 0.28 ENSMUST00000057067.10
ENSMUST00000189832.7
ENSMUST00000189391.2
meiotic double-stranded break formation protein 4
chr6_+_134617903 0.27 ENSMUST00000062755.10
BLOC-1 related complex subunit 5
chr3_-_49711765 0.27 ENSMUST00000035931.13
protocadherin 18
chr15_-_3333003 0.27 ENSMUST00000165386.2
coiled-coil domain containing 152
chr6_+_78382131 0.26 ENSMUST00000023906.4
regenerating islet-derived 2
chr6_-_108162513 0.25 ENSMUST00000167338.8
ENSMUST00000172188.2
ENSMUST00000032191.16
sulfatase modifying factor 1
chr9_-_15212745 0.24 ENSMUST00000217042.2
RIKEN cDNA 4931406C07 gene
chr17_-_40630096 0.24 ENSMUST00000026498.5
cysteine-rich secretory protein 1
chr14_-_68771138 0.24 ENSMUST00000022640.8
a disintegrin and metallopeptidase domain 7
chr8_+_72973560 0.24 ENSMUST00000003123.10
family with sequence similarity 32, member A
chr16_-_48592372 0.23 ENSMUST00000231701.3
T cell receptor associated transmembrane adaptor 1
chr8_+_121842902 0.23 ENSMUST00000054691.8
forkhead box C2
chr2_+_124978518 0.23 ENSMUST00000238754.2
cortexin 2
chr16_+_11224481 0.23 ENSMUST00000122168.8
sorting nexin 29
chr15_+_79113341 0.22 ENSMUST00000163571.8
protein interacting with C kinase 1
chr7_+_18853778 0.21 ENSMUST00000053109.5
F-box protein 46
chr3_-_94949854 0.21 ENSMUST00000117355.2
ENSMUST00000071664.12
ENSMUST00000107237.8
proteasome (prosome, macropain) 26S subunit, non-ATPase, 4
chr1_+_155911136 0.21 ENSMUST00000111757.10
torsin A interacting protein 2
chr19_+_43741550 0.21 ENSMUST00000153295.2
cutC copper transporter
chr11_+_97732108 0.21 ENSMUST00000155954.3
ENSMUST00000164364.2
ENSMUST00000170806.2
RIKEN cDNA B230217C12 gene
chr4_-_14621669 0.21 ENSMUST00000143105.2
solute carrier family 26, member 7
chr5_+_88073483 0.20 ENSMUST00000113271.3
casein kappa
chr12_+_86993805 0.20 ENSMUST00000189246.7
CLOCK interacting protein, circadian
chr2_+_69727599 0.19 ENSMUST00000131553.2
ubiquitin protein ligase E3 component n-recognin 3
chr2_+_127696548 0.19 ENSMUST00000028859.8
acyl-Coenzyme A oxidase-like
chr8_-_55177352 0.19 ENSMUST00000129132.3
ENSMUST00000150488.8
ENSMUST00000127511.9
WD repeat domain 17
chr4_-_14621805 0.19 ENSMUST00000042221.14
solute carrier family 26, member 7
chr17_+_26934617 0.19 ENSMUST00000062519.14
ENSMUST00000144221.2
ENSMUST00000142539.8
ENSMUST00000151681.2
CREB3 regulatory factor
chr4_-_94817025 0.19 ENSMUST00000030309.6
equatorin, sperm acrosome associated
chr13_+_67981349 0.19 ENSMUST00000222626.2
ENSMUST00000060609.8
predicted gene 10037
chr14_+_70077841 0.19 ENSMUST00000022678.5
phosphatidylethanolamine binding protein 4
chr6_+_125026865 0.18 ENSMUST00000112413.8
proacrosin binding protein
chr17_+_79223946 0.17 ENSMUST00000063817.7
CCAAT/enhancer binding protein (C/EBP), zeta, opposite strand
chr2_+_36575800 0.17 ENSMUST00000213258.2
olfactory receptor 346
chr6_+_65019793 0.17 ENSMUST00000204696.3
SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1
chr19_-_44541270 0.17 ENSMUST00000166808.2
predicted gene 20538
chr9_-_102231884 0.17 ENSMUST00000035129.14
ENSMUST00000085169.12
ENSMUST00000149800.3
Eph receptor B1
chr9_+_100479732 0.17 ENSMUST00000124487.8
stromal antigen 1
chr1_-_160405464 0.17 ENSMUST00000238289.2
G protein-coupled receptor 52
chr2_+_87854404 0.17 ENSMUST00000217006.2
olfactory receptor 1161
chr14_-_54520382 0.16 ENSMUST00000059996.7
olfactory receptor 49
chr18_-_73887528 0.16 ENSMUST00000041138.3
elaC ribonuclease Z 1
chr5_+_107655487 0.16 ENSMUST00000143074.2
predicted gene 42669
chr2_+_124978612 0.16 ENSMUST00000099452.3
ENSMUST00000238377.2
cortexin 2
chr4_-_86587728 0.16 ENSMUST00000149700.8
perilipin 2
chr14_+_122272069 0.16 ENSMUST00000045976.7
translocase of inner mitochondrial membrane 8A2
chr16_-_17379103 0.16 ENSMUST00000232637.2
ENSMUST00000100123.10
ENSMUST00000023442.13
leucine rich repeat containing 74B
chr3_+_41517790 0.16 ENSMUST00000163764.8
jade family PHD finger 1
chr14_+_53574579 0.16 ENSMUST00000179580.3
T cell receptor alpha variable 13N-3
chrM_-_14061 0.15 ENSMUST00000082419.1
mitochondrially encoded NADH dehydrogenase 6
chr1_+_88234454 0.15 ENSMUST00000040210.14
transient receptor potential cation channel, subfamily M, member 8
chrX_-_111315519 0.15 ENSMUST00000124335.8
spermidine/spermine N1-acetyl transferase-like 1
chr5_+_14564932 0.15 ENSMUST00000182407.8
ENSMUST00000030691.17
piccolo (presynaptic cytomatrix protein)
chr12_+_116239006 0.15 ENSMUST00000090195.5
predicted gene 11027
chr9_-_123461593 0.15 ENSMUST00000026273.11
solute carrier family 6 (neurotransmitter transporter), member 20B
chr5_+_87814058 0.15 ENSMUST00000199506.5
ENSMUST00000197631.5
ENSMUST00000094641.9
casein alpha s1
chr14_-_63221950 0.15 ENSMUST00000100493.3
defensin beta 48
chr4_+_102843540 0.14 ENSMUST00000030248.12
ENSMUST00000125417.9
ENSMUST00000169211.3
dynein light chain Tctex-type 5
chr17_+_14087827 0.14 ENSMUST00000239324.2
afadin, adherens junction formation factor
chr13_-_67599702 0.14 ENSMUST00000225479.2
ENSMUST00000057241.15
ENSMUST00000075255.6
zinc finger protein 874a
chr9_+_18320390 0.14 ENSMUST00000098973.3
upstream binding transcription factor, RNA polymerase I-like 1
chr13_+_23343482 0.14 ENSMUST00000226845.2
ENSMUST00000228666.2
ENSMUST00000227388.2
vomeronasal 1 receptor 219
chrX_+_72719098 0.14 ENSMUST00000171398.2
solute carrier family 6 (neurotransmitter transporter, creatine), member 8
chr13_+_22563988 0.13 ENSMUST00000227685.2
ENSMUST00000227689.2
ENSMUST00000227846.2
vomeronasal 1 receptor 199
chr5_+_88073438 0.13 ENSMUST00000001667.13
ENSMUST00000113267.8
casein kappa
chr9_+_121606750 0.13 ENSMUST00000098272.4
kelch-like 40
chr10_+_61007733 0.13 ENSMUST00000122261.8
ENSMUST00000121297.8
ENSMUST00000035894.12
thymus, brain and testes associated
chr8_-_62355690 0.13 ENSMUST00000121785.9
ENSMUST00000034057.14
palladin, cytoskeletal associated protein
chr16_-_44153288 0.13 ENSMUST00000136381.8
SID1 transmembrane family, member 1
chr1_+_44187007 0.13 ENSMUST00000027214.4
excision repair cross-complementing rodent repair deficiency, complementation group 5
chr7_-_19621833 0.13 ENSMUST00000052605.8
carcinoembryonic antigen-related cell adhesion molecule 19
chr9_-_107749594 0.13 ENSMUST00000183035.2
RNA binding motif protein 6
chr14_-_51433380 0.12 ENSMUST00000051274.2
angiogenin, ribonuclease A family, member 2
chr1_-_169938298 0.12 ENSMUST00000192312.6
discoidin domain receptor family, member 2
chr13_+_19394484 0.12 ENSMUST00000200495.2
T cell receptor gamma joining 1
chr15_-_35938155 0.12 ENSMUST00000156915.3
cytochrome c oxidase subunit 6C
chr7_-_106392405 0.12 ENSMUST00000215952.2
ENSMUST00000216307.2
olfactory receptor 699
chrM_+_8603 0.12 ENSMUST00000082409.1
mitochondrially encoded cytochrome c oxidase III
chr5_-_25107313 0.12 ENSMUST00000131486.2
protein kinase, AMP-activated, gamma 2 non-catalytic subunit
chr11_-_97909134 0.11 ENSMUST00000107561.9
calcium channel, voltage-dependent, beta 1 subunit
chr14_+_65504067 0.11 ENSMUST00000224629.2
F-box protein 16
chr8_+_22682816 0.11 ENSMUST00000033866.9
vacuolar protein sorting 36
chr2_-_17465410 0.11 ENSMUST00000145492.2
nebulette
chr1_-_139304832 0.11 ENSMUST00000198445.5
crumbs family member 1, photoreceptor morphogenesis associated
chr3_+_87343071 0.11 ENSMUST00000194102.6
Fc receptor-like 5
chr4_+_147592057 0.11 ENSMUST00000063704.8
zinc finger protein 982
chr4_-_101838246 0.10 ENSMUST00000106916.2
predicted gene 12790
chr3_+_87343127 0.10 ENSMUST00000166297.7
ENSMUST00000049926.15
ENSMUST00000178261.3
Fc receptor-like 5
chr3_+_87343105 0.10 ENSMUST00000193229.6
Fc receptor-like 5
chr1_+_173876771 0.10 ENSMUST00000213381.2
ENSMUST00000213211.2
olfactory receptor 432
chr4_-_14621497 0.10 ENSMUST00000149633.2
solute carrier family 26, member 7
chrY_-_1245685 0.10 ENSMUST00000143286.8
ENSMUST00000137048.8
ENSMUST00000069309.14
ENSMUST00000139365.8
ENSMUST00000154004.8
ubiquitously transcribed tetratricopeptide repeat containing, Y-linked
chr5_+_73164226 0.10 ENSMUST00000031127.11
ENSMUST00000201304.2
solute carrier family 10 (sodium/bile acid cotransporter family), member 4
chr1_+_46105898 0.10 ENSMUST00000069293.10
dynein, axonemal, heavy chain 7B
chr7_-_106354591 0.10 ENSMUST00000214306.2
ENSMUST00000216255.2
olfactory receptor 698
chr19_+_4015900 0.09 ENSMUST00000025794.7
aldehyde dehydrogenase 3 family, member B3
chr10_-_128885867 0.09 ENSMUST00000216460.2
olfactory receptor 765
chr10_+_29074950 0.09 ENSMUST00000217011.2
predicted gene, 49353
chr8_-_65582206 0.09 ENSMUST00000098713.5
small integral membrane protein 31
chr2_+_85876205 0.09 ENSMUST00000213496.2
olfactory receptor 1034
chr11_+_58485940 0.09 ENSMUST00000214990.2
ENSMUST00000216965.2
olfactory receptor 324
chr7_-_106531426 0.09 ENSMUST00000215468.2
olfactory receptor 709, pseudogene 1
chr2_+_57887896 0.09 ENSMUST00000112616.8
ENSMUST00000166729.2
polypeptide N-acetylgalactosaminyltransferase 5
chr7_+_126575781 0.09 ENSMUST00000206450.2
ENSMUST00000205830.2
CDP-diacylglycerol--inositol 3-phosphatidyltransferase (phosphatidylinositol synthase)
chr6_+_67873135 0.09 ENSMUST00000103310.3
immunoglobulin kappa variable 14-126
chrX_+_163221035 0.09 ENSMUST00000033755.6
ankyrin repeat and SOCS box-containing 11
chr14_+_53562089 0.09 ENSMUST00000178100.3
T cell receptor alpha variable 7N-6
chr4_-_94817056 0.09 ENSMUST00000107097.9
equatorin, sperm acrosome associated
chr13_+_22508759 0.09 ENSMUST00000226225.2
ENSMUST00000227017.2
vomeronasal 1 receptor 197
chr4_+_139380849 0.09 ENSMUST00000030510.14
ENSMUST00000166773.2
taste receptor, type 1, member 2
chr7_-_103191924 0.09 ENSMUST00000214269.3
olfactory receptor 612
chr2_+_36263531 0.08 ENSMUST00000072114.4
ENSMUST00000217511.2
olfactory receptor 338
chr8_+_96429665 0.08 ENSMUST00000073139.14
ENSMUST00000080666.8
ENSMUST00000212160.2
N-myc downstream regulated gene 4
chr4_+_146033882 0.08 ENSMUST00000105730.2
ENSMUST00000091878.6
zinc finger protein 987
chr6_-_70313491 0.08 ENSMUST00000103388.4
immunoglobulin kappa variable 6-20
chr7_-_139982831 0.08 ENSMUST00000080153.4
ENSMUST00000216053.2
ENSMUST00000217167.2
olfactory receptor 531
chr3_+_84081411 0.08 ENSMUST00000193882.2
predicted pseudogene 6525
chr18_-_36899245 0.08 ENSMUST00000061522.8
DND microRNA-mediated repression inhibitor 1

Network of associatons between targets according to the STRING database.

First level regulatory network of Isl2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
2.3 9.1 GO:0033869 coenzyme A catabolic process(GO:0015938) nucleoside bisphosphate catabolic process(GO:0033869) ribonucleoside bisphosphate catabolic process(GO:0034031) purine nucleoside bisphosphate catabolic process(GO:0034034) acetyl-CoA catabolic process(GO:0046356)
0.6 1.9 GO:0018879 biphenyl metabolic process(GO:0018879)
0.3 3.0 GO:0052696 flavonoid glucuronidation(GO:0052696) xenobiotic glucuronidation(GO:0052697)
0.2 0.6 GO:1903487 regulation of lactation(GO:1903487)
0.2 1.1 GO:0061017 hepatoblast differentiation(GO:0061017)
0.2 0.7 GO:0019287 isopentenyl diphosphate biosynthetic process, mevalonate pathway(GO:0019287)
0.1 4.7 GO:0019373 epoxygenase P450 pathway(GO:0019373)
0.1 2.1 GO:0015747 urate transport(GO:0015747)
0.1 0.7 GO:0002317 plasma cell differentiation(GO:0002317)
0.1 0.5 GO:0071596 ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596)
0.1 2.0 GO:0060363 cranial suture morphogenesis(GO:0060363)
0.1 0.3 GO:0052572 interleukin-15 production(GO:0032618) response to immune response of other organism involved in symbiotic interaction(GO:0052564) response to host immune response(GO:0052572)
0.1 0.3 GO:0042138 meiotic DNA double-strand break formation(GO:0042138)
0.1 0.5 GO:0001920 negative regulation of receptor recycling(GO:0001920)
0.1 0.2 GO:0035470 positive regulation of vascular wound healing(GO:0035470)
0.1 0.3 GO:0090118 regulation of phosphatidylcholine catabolic process(GO:0010899) receptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport(GO:0090118) positive regulation of lysosomal protein catabolic process(GO:1905167)
0.1 3.1 GO:0032094 response to food(GO:0032094)
0.1 0.4 GO:0009235 cobalamin metabolic process(GO:0009235)
0.1 0.7 GO:0015868 purine ribonucleotide transport(GO:0015868)
0.1 0.3 GO:0044330 canonical Wnt signaling pathway involved in positive regulation of wound healing(GO:0044330)
0.1 0.4 GO:0003383 apical constriction(GO:0003383)
0.1 0.5 GO:0019532 oxalate transport(GO:0019532)
0.1 0.4 GO:1903208 neuron death in response to hydrogen peroxide(GO:0036476) regulation of hydrogen peroxide-induced neuron death(GO:1903207) negative regulation of hydrogen peroxide-induced neuron death(GO:1903208)
0.1 1.1 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.0 0.1 GO:0099526 presynaptic signal transduction(GO:0098928) presynapse to nucleus signaling pathway(GO:0099526)
0.0 0.4 GO:0033762 response to glucagon(GO:0033762)
0.0 0.3 GO:0060478 acrosomal vesicle exocytosis(GO:0060478)
0.0 0.1 GO:0015881 creatine transport(GO:0015881)
0.0 0.1 GO:0006295 nucleotide-excision repair, DNA incision, 3'-to lesion(GO:0006295)
0.0 0.5 GO:0070131 positive regulation of mitochondrial translation(GO:0070131)
0.0 0.2 GO:0038161 prolactin signaling pathway(GO:0038161)
0.0 1.1 GO:0006767 water-soluble vitamin metabolic process(GO:0006767)
0.0 0.2 GO:0032918 polyamine acetylation(GO:0032917) spermidine acetylation(GO:0032918)
0.0 0.1 GO:0043328 protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043328)
0.0 0.2 GO:0042780 tRNA 3'-end processing(GO:0042780)
0.0 0.3 GO:0009048 dosage compensation(GO:0007549) dosage compensation by inactivation of X chromosome(GO:0009048)
0.0 0.3 GO:0021902 commitment of neuronal cell to specific neuron type in forebrain(GO:0021902)
0.0 0.6 GO:0050667 homocysteine metabolic process(GO:0050667)
0.0 0.2 GO:0034316 negative regulation of Arp2/3 complex-mediated actin nucleation(GO:0034316)
0.0 0.3 GO:0050859 negative regulation of B cell receptor signaling pathway(GO:0050859)
0.0 0.1 GO:0034334 adherens junction maintenance(GO:0034334)
0.0 0.1 GO:0031635 adenylate cyclase-inhibiting opioid receptor signaling pathway(GO:0031635)
0.0 0.2 GO:2001015 optic nerve morphogenesis(GO:0021631) negative regulation of skeletal muscle cell differentiation(GO:2001015)
0.0 0.2 GO:0033227 dsRNA transport(GO:0033227)
0.0 0.1 GO:0050916 sensory perception of sweet taste(GO:0050916)
0.0 0.1 GO:0098528 skeletal muscle fiber differentiation(GO:0098528)
0.0 0.1 GO:0070268 cornification(GO:0070268)
0.0 0.1 GO:0060005 vestibular reflex(GO:0060005)
0.0 0.6 GO:0008206 bile acid metabolic process(GO:0008206)
0.0 0.6 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.0 0.2 GO:0050955 thermoception(GO:0050955)
0.0 0.2 GO:0043248 proteasome assembly(GO:0043248)
0.0 0.1 GO:1902714 negative regulation of interferon-gamma secretion(GO:1902714)
0.0 0.1 GO:0071557 histone H3-K27 demethylation(GO:0071557)
0.0 0.3 GO:0042572 retinol metabolic process(GO:0042572)
0.0 0.2 GO:0090435 protein localization to nuclear envelope(GO:0090435)
0.0 0.8 GO:0046513 ceramide biosynthetic process(GO:0046513)
0.0 0.1 GO:0090669 telomerase RNA stabilization(GO:0090669)
0.0 0.1 GO:0097680 double-strand break repair via classical nonhomologous end joining(GO:0097680)
0.0 0.3 GO:0001967 suckling behavior(GO:0001967)
0.0 0.0 GO:2000360 negative regulation of binding of sperm to zona pellucida(GO:2000360)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 2.0 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.1 1.9 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.1 0.3 GO:1990666 PCSK9-LDLR complex(GO:1990666)
0.1 0.2 GO:0098842 postsynaptic early endosome(GO:0098842)
0.1 0.3 GO:0002079 inner acrosomal membrane(GO:0002079)
0.0 0.1 GO:0044317 rod spherule(GO:0044317)
0.0 0.4 GO:0033269 internode region of axon(GO:0033269)
0.0 10.2 GO:0042579 peroxisome(GO:0005777) microbody(GO:0042579)
0.0 0.1 GO:0000814 ESCRT II complex(GO:0000814)
0.0 0.3 GO:0098574 cytoplasmic side of lysosomal membrane(GO:0098574)
0.0 0.4 GO:0045275 respiratory chain complex III(GO:0045275)
0.0 0.4 GO:0043020 NADPH oxidase complex(GO:0043020)
0.0 0.7 GO:0005922 connexon complex(GO:0005922)
0.0 2.2 GO:0070469 respiratory chain(GO:0070469)
0.0 0.6 GO:0042101 T cell receptor complex(GO:0042101)
0.0 0.2 GO:0008540 proteasome regulatory particle, base subcomplex(GO:0008540)
0.0 0.3 GO:0071004 U2-type prespliceosome(GO:0071004)
0.0 0.1 GO:0097637 intrinsic component of autophagosome membrane(GO:0097636) integral component of autophagosome membrane(GO:0097637)
0.0 0.0 GO:0060473 cortical granule(GO:0060473)
0.0 0.2 GO:0036156 inner dynein arm(GO:0036156)
0.0 0.3 GO:0005614 interstitial matrix(GO:0005614)
0.0 0.1 GO:0005958 DNA-dependent protein kinase-DNA ligase 4 complex(GO:0005958) DNA ligase IV complex(GO:0032807)
0.0 0.4 GO:0042588 zymogen granule(GO:0042588)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.8 9.1 GO:0003986 acetyl-CoA hydrolase activity(GO:0003986)
0.5 2.0 GO:0047961 glycine N-acyltransferase activity(GO:0047961)
0.2 0.6 GO:0008775 acetate CoA-transferase activity(GO:0008775)
0.2 0.8 GO:0042284 sphingolipid delta-4 desaturase activity(GO:0042284)
0.1 5.7 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.1 2.3 GO:0015143 urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.1 4.7 GO:0008392 arachidonic acid epoxygenase activity(GO:0008392)
0.1 0.3 GO:0042392 sphingosine-1-phosphate phosphatase activity(GO:0042392)
0.1 2.2 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.1 1.1 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.1 0.6 GO:0016174 NAD(P)H oxidase activity(GO:0016174)
0.1 0.2 GO:0001588 dopamine neurotransmitter receptor activity, coupled via Gs(GO:0001588)
0.1 0.3 GO:0032450 maltose alpha-glucosidase activity(GO:0032450)
0.0 0.4 GO:0008121 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.0 0.1 GO:0005308 creatine transmembrane transporter activity(GO:0005308)
0.0 0.7 GO:0005243 gap junction channel activity(GO:0005243)
0.0 0.2 GO:0019809 spermidine binding(GO:0019809)
0.0 0.3 GO:0030229 very-low-density lipoprotein particle receptor activity(GO:0030229)
0.0 0.2 GO:0051033 nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033)
0.0 0.5 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.0 0.2 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.0 0.6 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
0.0 0.1 GO:0005152 interleukin-1 receptor antagonist activity(GO:0005152)
0.0 0.2 GO:0003997 acyl-CoA oxidase activity(GO:0003997)
0.0 0.1 GO:0008607 phosphorylase kinase regulator activity(GO:0008607)
0.0 0.3 GO:0008106 alcohol dehydrogenase (NADP+) activity(GO:0008106)
0.0 0.1 GO:0000405 bubble DNA binding(GO:0000405)
0.0 0.2 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.0 0.1 GO:0071558 histone demethylase activity (H3-K27 specific)(GO:0071558)
0.0 3.1 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 0.1 GO:0004030 aldehyde dehydrogenase [NAD(P)+] activity(GO:0004030)
0.0 0.0 GO:0070002 glutamic-type peptidase activity(GO:0070002)
0.0 0.3 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.0 0.1 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.0 0.7 GO:0016776 phosphotransferase activity, phosphate group as acceptor(GO:0016776)
0.0 0.3 GO:0015002 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 0.1 GO:0004985 opioid receptor activity(GO:0004985)
0.0 1.1 GO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides(GO:0016811)
0.0 0.5 GO:0005044 scavenger receptor activity(GO:0005044)

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 2.9 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.1 0.8 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.1 0.3 REACTOME DIGESTION OF DIETARY CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
0.1 3.1 REACTOME METABOLISM OF STEROID HORMONES AND VITAMINS A AND D Genes involved in Metabolism of steroid hormones and vitamins A and D
0.1 0.6 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0 0.7 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.0 0.7 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 0.6 REACTOME DOWNSTREAM TCR SIGNALING Genes involved in Downstream TCR signaling
0.0 0.4 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0 0.9 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.0 0.3 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport