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GSE58827: Dynamics of the Mouse Liver

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Results for Klf15

Z-value: 1.61

Motif logo

Transcription factors associated with Klf15

Gene Symbol Gene ID Gene Info
ENSMUSG00000030087.12 Kruppel-like factor 15

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Klf15mm39_v1_chr6_+_90439544_904395650.798.8e-09Click!

Activity profile of Klf15 motif

Sorted Z-values of Klf15 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr7_-_99276310 9.43 ENSMUST00000178124.3
trophoblast glycoprotein-like
chr17_+_31605184 8.06 ENSMUST00000047168.13
ENSMUST00000127929.8
ENSMUST00000134525.9
ENSMUST00000236454.2
ENSMUST00000238091.2
ENSMUST00000235719.2
phosphodiesterase 9A
chr5_+_21391282 8.03 ENSMUST00000036031.13
ENSMUST00000198937.2
gamma-secretase activating protein
chr4_+_139350152 7.47 ENSMUST00000039818.10
aldehyde dehydrogenase 4 family, member A1
chr8_-_41586713 7.37 ENSMUST00000155055.2
ENSMUST00000059115.13
ENSMUST00000145860.2
mitochondrial tumor suppressor 1
chr18_-_38345010 7.24 ENSMUST00000159405.3
ENSMUST00000160721.8
protocadherin 1
chr6_+_54016543 7.13 ENSMUST00000046856.14
chimerin 2
chr2_-_5719302 6.59 ENSMUST00000044009.14
calcium/calmodulin-dependent protein kinase ID
chr9_-_21838584 6.59 ENSMUST00000213698.2
transmembrane protein 205
chr9_-_21838758 6.33 ENSMUST00000046831.11
ENSMUST00000238930.2
transmembrane protein 205
chr10_-_53951825 6.31 ENSMUST00000003843.16
mannosidase 1, alpha
chr9_-_43151179 6.02 ENSMUST00000034512.7
out at first homolog
chr11_+_98239230 5.87 ENSMUST00000078694.13
protein phosphatase 1, regulatory inhibitor subunit 1B
chr10_-_53951796 5.66 ENSMUST00000105470.9
mannosidase 1, alpha
chr14_-_20844074 5.65 ENSMUST00000080440.14
ENSMUST00000100837.11
ENSMUST00000071816.7
calcium/calmodulin-dependent protein kinase II gamma
chr2_-_147887810 5.64 ENSMUST00000109964.8
forkhead box A2
chr16_-_97763780 5.61 ENSMUST00000232187.2
ENSMUST00000231263.2
ENSMUST00000052089.9
ENSMUST00000063605.15
ENSMUST00000113734.9
ENSMUST00000231560.2
ENSMUST00000232165.2
zinc finger and BTB domain containing 21
C2 calcium-dependent domain containing 2
chr7_-_16348862 5.28 ENSMUST00000171937.2
ENSMUST00000075845.11
Rho GTPase activating protein 35
chr9_+_108174052 4.40 ENSMUST00000035230.7
aminomethyltransferase
chrX_+_169106356 4.22 ENSMUST00000178693.4
acetylserotonin O-methyltransferase
chr4_+_107035566 4.18 ENSMUST00000030361.11
transmembrane protein 59
chr17_-_33166346 4.16 ENSMUST00000139353.8
cytochrome P450, family 4, subfamily f, polypeptide 13
chr2_+_128660212 4.09 ENSMUST00000143398.3
ENSMUST00000152210.2
transmembrane protein 87B
chr9_-_110571645 4.09 ENSMUST00000006005.12
parathyroid hormone 1 receptor
chr10_-_81262948 3.92 ENSMUST00000078185.14
ENSMUST00000020461.15
ENSMUST00000105321.10
nuclear factor I/C
chr19_+_53891802 3.86 ENSMUST00000165617.3
programmed cell death 4
chr4_+_107035615 3.75 ENSMUST00000128123.3
ENSMUST00000106753.3
transmembrane protein 59
chr11_-_100661762 3.73 ENSMUST00000139341.2
ENSMUST00000017891.14
GH3 domain containing
chr6_-_84564623 3.72 ENSMUST00000205228.3
cytochrome P450, family 26, subfamily b, polypeptide 1
chr9_+_21838767 3.65 ENSMUST00000006403.7
ENSMUST00000170304.9
ENSMUST00000216710.2
coiled-coil domain containing 159
chr2_+_32496990 3.60 ENSMUST00000095045.9
ENSMUST00000095044.10
ENSMUST00000126636.8
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6
chr14_-_64654397 3.47 ENSMUST00000210428.2
methionine sulfoxide reductase A
chr14_-_64654592 3.44 ENSMUST00000210363.2
methionine sulfoxide reductase A
chr4_-_118148471 3.34 ENSMUST00000222620.2
protein tyrosine phosphatase, receptor type, F
chr6_+_54017063 3.33 ENSMUST00000127323.3
chimerin 2
chr1_-_93406515 3.26 ENSMUST00000170883.8
ENSMUST00000189025.7
high density lipoprotein (HDL) binding protein
chr16_-_95883588 3.10 ENSMUST00000099502.9
ENSMUST00000023631.17
ENSMUST00000232755.2
bromodomain and WD repeat domain containing 1
chrX_-_146337046 3.10 ENSMUST00000112819.9
ENSMUST00000136789.8
leucine-rich repeats and calponin homology (CH) domain containing 2
chr4_-_118148537 3.08 ENSMUST00000049074.13
protein tyrosine phosphatase, receptor type, F
chr9_+_43996236 3.04 ENSMUST00000065461.9
ENSMUST00000176416.8
ubiquitin specific peptidase 2
chr10_-_80096793 3.00 ENSMUST00000020359.7
guanidinoacetate methyltransferase
chr11_-_72686627 2.97 ENSMUST00000079681.6
cytochrome b5 domain containing 2
chr10_-_80096842 2.91 ENSMUST00000105363.8
guanidinoacetate methyltransferase
chr10_+_80192293 2.91 ENSMUST00000039836.15
ENSMUST00000105351.2
polo like kinase 5
chr17_+_53873964 2.79 ENSMUST00000000724.15
K(lysine) acetyltransferase 2B
chr5_+_127709302 2.73 ENSMUST00000118139.3
glycosyltransferase 1 domain containing 1
chr9_+_107957621 2.70 ENSMUST00000035211.14
macrophage stimulating 1 (hepatocyte growth factor-like)
chr5_+_135093056 2.65 ENSMUST00000071263.7
DnaJ heat shock protein family (Hsp40) member C30
chr12_+_103498542 2.64 ENSMUST00000021631.12
protein phosphatase 4, regulatory subunit 4
chr9_+_107957640 2.63 ENSMUST00000162886.2
macrophage stimulating 1 (hepatocyte growth factor-like)
chr1_-_160862364 2.63 ENSMUST00000177003.2
ENSMUST00000159250.9
ENSMUST00000162226.9
zinc finger and BTB domain containing 37
chr14_-_20844034 2.62 ENSMUST00000226630.2
calcium/calmodulin-dependent protein kinase II gamma
chr1_-_93406091 2.61 ENSMUST00000188165.2
high density lipoprotein (HDL) binding protein
chr6_+_54249817 2.61 ENSMUST00000204921.3
ENSMUST00000203091.3
ENSMUST00000204115.3
ENSMUST00000203941.3
ENSMUST00000204746.2
chimerin 2
chr9_+_45817795 2.58 ENSMUST00000039059.8
proprotein convertase subtilisin/kexin type 7
chr1_-_74924481 2.57 ENSMUST00000159232.2
ENSMUST00000068631.4
FEV transcription factor, ETS family member
chr18_-_3337467 2.55 ENSMUST00000154135.8
ENSMUST00000142690.2
ENSMUST00000025069.11
ENSMUST00000165086.8
ENSMUST00000082141.12
ENSMUST00000149803.8
cAMP responsive element modulator
chr15_-_89064936 2.54 ENSMUST00000109331.9
plexin B2
chr15_-_78687216 2.54 ENSMUST00000164826.8
caspase recruitment domain family, member 10
chr6_-_113354668 2.54 ENSMUST00000193384.2
transcriptional adaptor 3
chr15_+_75865604 2.53 ENSMUST00000089669.6
mitogen-activated protein kinase 15
chr13_+_51254852 2.49 ENSMUST00000095797.6
spindlin 1
chr2_-_90410922 2.49 ENSMUST00000168621.3
protein tyrosine phosphatase, receptor type, J
chr5_-_138980690 2.49 ENSMUST00000046901.14
ENSMUST00000076095.14
platelet derived growth factor, alpha
chr12_-_108241597 2.44 ENSMUST00000222310.2
coiled-coil domain containing 85C
chr10_-_127502541 2.43 ENSMUST00000026469.9
Ngfi-A binding protein 2
chr8_+_108020132 2.41 ENSMUST00000151114.8
ENSMUST00000125721.8
ENSMUST00000075922.11
nuclear factor of activated T cells 5
chr2_+_128659997 2.37 ENSMUST00000110325.8
transmembrane protein 87B
chr15_+_87509413 2.36 ENSMUST00000068088.8
TAFA chemokine like family member 5
chrX_+_160500623 2.34 ENSMUST00000061514.8
retinoic acid induced 2
chr14_-_70757601 2.32 ENSMUST00000022693.9
bone morphogenetic protein 1
chr7_+_97229065 2.30 ENSMUST00000107153.3
remodeling and spacing factor 1
chr18_-_38068430 2.29 ENSMUST00000025337.14
diaphanous related formin 1
chr8_+_108020092 2.28 ENSMUST00000169453.8
nuclear factor of activated T cells 5
chr4_+_136197066 2.27 ENSMUST00000170102.8
ENSMUST00000105849.9
ENSMUST00000129230.3
leucine zipper protein 1
chr1_-_175319842 2.24 ENSMUST00000195324.6
ENSMUST00000192227.6
ENSMUST00000194555.6
regulator of G protein signaling 7
chr5_-_65650133 2.24 ENSMUST00000196121.2
predicted gene 43552
chr13_+_58550499 2.20 ENSMUST00000225815.2
RecQ mediated genome instability 1
chr19_-_44017637 2.18 ENSMUST00000026211.10
ENSMUST00000211830.2
cytochrome P450, family 2, subfamily c, polypeptide 23
chr2_+_140237366 2.18 ENSMUST00000110061.2
mono-ADP ribosylhydrolase 2
chr2_+_140237229 2.14 ENSMUST00000110067.8
ENSMUST00000110063.8
ENSMUST00000110064.8
ENSMUST00000110062.8
ENSMUST00000043836.8
ENSMUST00000078027.12
mono-ADP ribosylhydrolase 2
chr7_+_100355798 2.14 ENSMUST00000107042.9
ENSMUST00000207564.2
ENSMUST00000049053.9
family with sequence similarity 168, member A
chr4_+_131649001 2.14 ENSMUST00000094666.4
transmembrane protein 200B
chr10_-_127502467 2.12 ENSMUST00000099157.4
Ngfi-A binding protein 2
chr18_-_3337679 2.11 ENSMUST00000150235.8
ENSMUST00000154470.8
cAMP responsive element modulator
chr4_+_47353277 2.09 ENSMUST00000044234.14
transforming growth factor, beta receptor I
chr2_+_91087668 2.08 ENSMUST00000111349.9
ENSMUST00000131711.8
protein kinase C and casein kinase substrate in neurons 3
chr18_+_35963353 2.08 ENSMUST00000235169.2
CXXC finger 5
chr18_-_38068456 2.07 ENSMUST00000080033.7
ENSMUST00000115631.8
ENSMUST00000115634.8
diaphanous related formin 1
chr11_-_115310743 2.07 ENSMUST00000106537.8
ENSMUST00000043931.9
ENSMUST00000073791.10
ATP synthase, H+ transporting, mitochondrial F0 complex, subunit D
chr15_-_82783978 2.05 ENSMUST00000230403.2
transcription factor 20
chr3_-_30563611 2.00 ENSMUST00000173899.8
MDS1 and EVI1 complex locus
chr7_-_80052491 1.99 ENSMUST00000122232.8
furin (paired basic amino acid cleaving enzyme)
chr1_-_16589511 1.97 ENSMUST00000162751.8
ENSMUST00000027052.13
ENSMUST00000149320.9
staufen double-stranded RNA binding protein 2
chr17_+_43978377 1.97 ENSMUST00000233627.2
ENSMUST00000233437.2
cytochrome P450, family 39, subfamily a, polypeptide 1
chrX_+_140258381 1.93 ENSMUST00000112931.8
ENSMUST00000112930.8
collagen, type IV, alpha 5
chr9_+_60701749 1.92 ENSMUST00000214354.2
ENSMUST00000050183.7
ENSMUST00000217656.2
uveal autoantigen with coiled-coil domains and ankyrin repeats
chr17_+_43978280 1.85 ENSMUST00000170988.2
cytochrome P450, family 39, subfamily a, polypeptide 1
chr7_+_46045862 1.84 ENSMUST00000025202.8
potassium voltage gated channel, Shaw-related subfamily, member 1
chr17_+_11059309 1.83 ENSMUST00000233706.2
parkin RBR E3 ubiquitin protein ligase
chr19_-_29790352 1.78 ENSMUST00000099525.5
RAN binding protein 6
chr10_-_127098932 1.78 ENSMUST00000217895.2
kinesin family member 5A
chr11_+_115310963 1.78 ENSMUST00000106533.8
ENSMUST00000123345.2
potassium channel tetramerisation domain containing 2
chr4_+_47353217 1.78 ENSMUST00000007757.15
transforming growth factor, beta receptor I
chr13_+_81859460 1.74 ENSMUST00000057598.7
ENSMUST00000224299.2
metallo-beta-lactamase domain containing 2
chr10_+_62935430 1.74 ENSMUST00000044059.5
atonal bHLH transcription factor 7
chr17_+_86475205 1.73 ENSMUST00000097275.9
protein kinase C, epsilon
chr5_-_124563611 1.70 ENSMUST00000198420.5
strawberry notch 1
chr9_-_20657643 1.68 ENSMUST00000215999.2
olfactomedin 2
chr7_-_24643919 1.68 ENSMUST00000206705.3
ETS repressor factor like
chr2_-_84545504 1.66 ENSMUST00000035840.6
zinc finger, DHHC domain containing 5
chr11_-_119438569 1.66 ENSMUST00000026670.5
neuronal pentraxin 1
chr1_-_55401851 1.63 ENSMUST00000114423.7
boule homolog, RNA binding protein
chr18_+_35962881 1.60 ENSMUST00000237291.2
CXXC finger 5
chr11_-_97464755 1.59 ENSMUST00000126287.2
ENSMUST00000107590.9
SRC kinase signaling inhibitor 1
chr17_+_31783708 1.59 ENSMUST00000097352.11
ENSMUST00000237248.2
ENSMUST00000235869.2
ENSMUST00000175806.9
Pbx/knotted 1 homeobox
chr7_+_100355910 1.58 ENSMUST00000207875.2
ENSMUST00000208013.2
family with sequence similarity 168, member A
chr18_+_35962832 1.57 ENSMUST00000060722.8
CXXC finger 5
chr2_-_25982160 1.55 ENSMUST00000114159.9
nucleus accumbens associated 2, BEN and BTB (POZ) domain containing
chr16_-_94657531 1.55 ENSMUST00000232562.2
ENSMUST00000165538.3
potassium inwardly-rectifying channel, subfamily J, member 6
chr11_+_115310885 1.54 ENSMUST00000103035.10
potassium channel tetramerisation domain containing 2
chr9_-_81515865 1.53 ENSMUST00000183482.2
5-hydroxytryptamine (serotonin) receptor 1B
chr13_-_9814467 1.53 ENSMUST00000154994.8
ENSMUST00000146039.2
ENSMUST00000110635.8
ENSMUST00000110638.8
zinc finger, MYND domain containing 11
chr2_+_91087156 1.52 ENSMUST00000144394.8
ENSMUST00000028694.12
ENSMUST00000168916.8
ENSMUST00000156919.8
protein kinase C and casein kinase substrate in neurons 3
chr16_-_95883714 1.50 ENSMUST00000113827.4
bromodomain and WD repeat domain containing 1
chr11_-_97464866 1.50 ENSMUST00000207653.2
ENSMUST00000107593.8
SRC kinase signaling inhibitor 1
chr15_+_74827488 1.49 ENSMUST00000191436.7
ENSMUST00000191145.7
lymphocyte antigen 6 complex, locus E
chr19_+_6547790 1.47 ENSMUST00000113458.8
ENSMUST00000113459.2
neurexin II
chr13_-_9814407 1.47 ENSMUST00000146059.8
ENSMUST00000110637.8
zinc finger, MYND domain containing 11
chr11_+_77821626 1.45 ENSMUST00000093995.10
ENSMUST00000000646.14
seizure related gene 6
chr17_+_11059248 1.44 ENSMUST00000191124.7
parkin RBR E3 ubiquitin protein ligase
chr7_-_28329924 1.43 ENSMUST00000159095.2
ENSMUST00000159418.8
ENSMUST00000159560.3
acid phosphatase 7, tartrate resistant
chr12_-_98703664 1.43 ENSMUST00000170188.8
protein tyrosine phosphatase, non-receptor type 21
chr13_+_119565669 1.42 ENSMUST00000173627.8
ENSMUST00000126957.9
ENSMUST00000174691.8
polyadenylate binding protein-interacting protein 1
chr5_-_124564014 1.41 ENSMUST00000196329.5
ENSMUST00000196644.5
strawberry notch 1
chr15_+_99192968 1.40 ENSMUST00000128352.8
ENSMUST00000145482.8
pre-mRNA processing factor 40B
chr5_-_65650269 1.39 ENSMUST00000121661.8
small integral membrane protein 14
chr7_+_126376319 1.35 ENSMUST00000132643.2
yippee like 3
chr3_+_135144287 1.35 ENSMUST00000196591.5
ubiquitin-conjugating enzyme E2D 3
chr9_-_45817666 1.34 ENSMUST00000161187.8
ring finger protein 214
chr10_-_83173289 1.34 ENSMUST00000126617.2
solute carrier family 41, member 2
chr2_-_120144622 1.33 ENSMUST00000054651.8
phospholipase A2, group IVF
chr13_-_9814901 1.31 ENSMUST00000223421.2
ENSMUST00000128658.8
zinc finger, MYND domain containing 11
chr5_+_130477642 1.30 ENSMUST00000111288.4
calneuron 1
chr18_+_77273510 1.30 ENSMUST00000075290.8
ENSMUST00000079618.11
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 5
chr12_+_52550775 1.29 ENSMUST00000219443.2
Rho GTPase activating protein 5
chr11_-_100650566 1.29 ENSMUST00000107361.9
potassium voltage-gated channel, subfamily H (eag-related), member 4
chr13_+_58550046 1.27 ENSMUST00000225828.2
ENSMUST00000042450.10
RecQ mediated genome instability 1
chr6_+_110622533 1.26 ENSMUST00000071076.13
ENSMUST00000172951.2
glutamate receptor, metabotropic 7
chr13_-_46118433 1.26 ENSMUST00000167708.4
ENSMUST00000091628.11
ENSMUST00000180110.9
ataxin 1
chr15_-_83609127 1.24 ENSMUST00000171496.9
ENSMUST00000043634.12
ENSMUST00000076060.12
ENSMUST00000016907.8
signal peptide, CUB domain, EGF-like 1
chr1_+_55445033 1.24 ENSMUST00000042986.10
phospholipase C-like 1
chr11_-_116197994 1.22 ENSMUST00000124281.2
exocyst complex component 7
chr11_-_3813895 1.21 ENSMUST00000070552.14
oxysterol binding protein 2
chr17_-_28569721 1.19 ENSMUST00000156862.3
TEA domain family member 3
chr4_+_55350043 1.19 ENSMUST00000030134.9
RAD23 homolog B, nucleotide excision repair protein
chr4_+_97665992 1.18 ENSMUST00000107062.9
ENSMUST00000052018.12
ENSMUST00000107057.8
nuclear factor I/A
chr12_+_55646209 1.18 ENSMUST00000051857.5
insulinoma-associated 2
chr17_-_15596230 1.16 ENSMUST00000014917.8
delta like canonical Notch ligand 1
chr4_+_97665843 1.16 ENSMUST00000075448.13
ENSMUST00000092532.13
nuclear factor I/A
chr6_-_113354826 1.14 ENSMUST00000032410.14
transcriptional adaptor 3
chr1_+_75523166 1.14 ENSMUST00000138814.2
solute carrier family 4 (anion exchanger), member 3
chr4_+_131648509 1.13 ENSMUST00000238733.2
transmembrane protein 200B
chr5_-_124563969 1.12 ENSMUST00000065263.12
strawberry notch 1
chr7_+_127111576 1.12 ENSMUST00000186672.7
Snf2-related CREBBP activator protein
chr4_+_129878627 1.12 ENSMUST00000120204.8
adhesion G protein-coupled receptor B2
chr16_-_13977084 1.11 ENSMUST00000090300.6
meiosis regulator and mRNA stability 1
chr2_-_63014622 1.10 ENSMUST00000075052.10
ENSMUST00000112454.8
potassium voltage-gated channel, subfamily H (eag-related), member 7
chr5_+_30745447 1.09 ENSMUST00000066295.5
potassium channel, subfamily K, member 3
chr10_-_77879414 1.05 ENSMUST00000145975.8
ENSMUST00000130972.8
ENSMUST00000128241.8
ENSMUST00000155021.8
ENSMUST00000140636.8
ENSMUST00000148469.8
ENSMUST00000019257.15
ENSMUST00000105395.9
ENSMUST00000156417.8
ENSMUST00000105396.9
ENSMUST00000154374.2
autoimmune regulator (autoimmune polyendocrinopathy candidiasis ectodermal dystrophy)
chr7_-_28330322 1.05 ENSMUST00000040112.5
ENSMUST00000239470.2
acid phosphatase 7, tartrate resistant
chr18_-_89787603 1.05 ENSMUST00000097495.5
docking protein 6
chr7_+_16609227 1.03 ENSMUST00000108493.3
dishevelled-binding antagonist of beta-catenin 3
chr11_+_76563281 1.02 ENSMUST00000056184.2
basic helix-loop-helix family, member a9
chr17_-_25652236 1.01 ENSMUST00000159623.2
calcium channel, voltage-dependent, T type, alpha 1H subunit
chr1_+_105918383 1.01 ENSMUST00000119166.8
zinc finger, CCHC domain containing 2
chr17_+_27152012 1.00 ENSMUST00000073724.7
ENSMUST00000237189.2
PHD finger protein 1
chr2_-_26335187 1.00 ENSMUST00000114082.9
ENSMUST00000091252.5
SEC16 homolog A, endoplasmic reticulum export factor
chr5_-_135092904 0.98 ENSMUST00000111205.8
ENSMUST00000141309.2
BUD23, rRNA methyltransferase and ribosome maturation factor
chr19_+_48194464 0.98 ENSMUST00000078880.6
sortilin-related VPS10 domain containing receptor 3
chr10_-_84938350 0.97 ENSMUST00000059383.8
ENSMUST00000216889.2
four and a half LIM domains 4
chr8_-_35432783 0.96 ENSMUST00000033929.6
tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase
chrX_-_58179754 0.95 ENSMUST00000033473.12
fibroblast growth factor 13
chr9_+_21077010 0.95 ENSMUST00000039413.15
phosphodiesterase 4A, cAMP specific
chr1_+_93406809 0.94 ENSMUST00000112912.8
septin 2
chr1_+_105918114 0.94 ENSMUST00000118196.8
zinc finger, CCHC domain containing 2
chr11_-_52173391 0.94 ENSMUST00000086844.10
transcription factor 7, T cell specific
chr11_-_116197523 0.94 ENSMUST00000133468.2
ENSMUST00000106411.10
ENSMUST00000106413.10
ENSMUST00000021147.14
exocyst complex component 7
chr18_+_61178211 0.92 ENSMUST00000025522.11
ENSMUST00000115274.2
platelet derived growth factor receptor, beta polypeptide
chr5_-_71815318 0.92 ENSMUST00000199357.2
gamma-aminobutyric acid (GABA) A receptor, subunit alpha 4
chr1_-_16589425 0.90 ENSMUST00000159558.8
ENSMUST00000054668.13
ENSMUST00000162627.8
ENSMUST00000162007.8
ENSMUST00000128957.9
ENSMUST00000115359.10
ENSMUST00000151888.8
staufen double-stranded RNA binding protein 2
chr4_+_155334417 0.89 ENSMUST00000178473.8
ENSMUST00000105627.8
ENSMUST00000097747.9
Fanconi anemia core complex associated protein 20
chr3_+_94385661 0.87 ENSMUST00000200342.5
CUGBP, Elav-like family member 3
chr2_-_63014514 0.86 ENSMUST00000112452.2
potassium voltage-gated channel, subfamily H (eag-related), member 7
chr13_-_99653045 0.86 ENSMUST00000064762.6
microtubule-associated protein 1B
chr17_-_25716189 0.86 ENSMUST00000165183.10
ENSMUST00000051864.5
somatostatin receptor 5
chr13_-_58261406 0.85 ENSMUST00000160860.9
kelch-like 3
chr11_-_100541519 0.85 ENSMUST00000103119.10
zinc finger protein 385C
chr13_-_9814979 0.84 ENSMUST00000110634.8
zinc finger, MYND domain containing 11
chr9_+_89791943 0.84 ENSMUST00000189545.2
ENSMUST00000034909.11
ENSMUST00000034912.6
RAS protein-specific guanine nucleotide-releasing factor 1

Network of associatons between targets according to the STRING database.

First level regulatory network of Klf15

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
2.6 7.9 GO:0090285 negative regulation of protein glycosylation in Golgi(GO:0090285)
2.5 7.5 GO:0010133 proline catabolic process to glutamate(GO:0010133)
2.0 5.9 GO:0006601 creatine biosynthetic process(GO:0006601)
1.9 5.6 GO:0045013 carbon catabolite repression of transcription(GO:0045013) negative regulation of transcription by glucose(GO:0045014)
1.5 4.4 GO:0019464 glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464)
1.4 4.2 GO:2000019 negative regulation of male gonad development(GO:2000019)
1.3 3.9 GO:1905223 epicardium morphogenesis(GO:1905223)
1.3 3.9 GO:0060938 cardiac fibroblast cell differentiation(GO:0060935) cardiac fibroblast cell development(GO:0060936) epicardium-derived cardiac fibroblast cell differentiation(GO:0060938) epicardium-derived cardiac fibroblast cell development(GO:0060939) negative regulation of myofibroblast differentiation(GO:1904761) negative regulation of vascular smooth muscle cell differentiation(GO:1905064)
1.3 3.8 GO:0030573 bile acid catabolic process(GO:0030573)
1.2 2.5 GO:0010512 negative regulation of phosphatidylinositol biosynthetic process(GO:0010512)
1.2 5.9 GO:0007621 negative regulation of female receptivity(GO:0007621)
1.1 6.4 GO:0051387 negative regulation of neurotrophin TRK receptor signaling pathway(GO:0051387)
0.9 3.7 GO:1905053 regulation of base-excision repair(GO:1905051) positive regulation of base-excision repair(GO:1905053)
0.9 0.9 GO:2000591 positive regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway(GO:0035793) regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway(GO:1900238) positive regulation of metanephric mesenchymal cell migration(GO:2000591)
0.8 5.3 GO:0030950 establishment or maintenance of actin cytoskeleton polarity(GO:0030950)
0.7 2.9 GO:0098964 dendritic transport of ribonucleoprotein complex(GO:0098961) dendritic transport of messenger ribonucleoprotein complex(GO:0098963) anterograde dendritic transport of messenger ribonucleoprotein complex(GO:0098964)
0.7 6.6 GO:0060267 positive regulation of respiratory burst(GO:0060267)
0.7 2.6 GO:0080163 regulation of protein serine/threonine phosphatase activity(GO:0080163)
0.6 3.7 GO:0035981 tongue muscle cell differentiation(GO:0035981) positive regulation of skeletal muscle fiber differentiation(GO:1902811) regulation of tongue muscle cell differentiation(GO:2001035) positive regulation of tongue muscle cell differentiation(GO:2001037)
0.6 4.3 GO:0051725 protein de-ADP-ribosylation(GO:0051725)
0.6 5.3 GO:0060763 mammary duct terminal end bud growth(GO:0060763)
0.6 3.5 GO:0002023 reduction of food intake in response to dietary excess(GO:0002023)
0.6 2.3 GO:0016584 nucleosome positioning(GO:0016584)
0.5 1.6 GO:1900477 negative regulation of G1/S transition of mitotic cell cycle by negative regulation of transcription from RNA polymerase II promoter(GO:1900477)
0.5 4.6 GO:0016480 negative regulation of transcription from RNA polymerase III promoter(GO:0016480)
0.5 2.0 GO:0090472 dibasic protein processing(GO:0090472)
0.4 1.3 GO:0071603 trabecular meshwork development(GO:0002930) endothelial cell-cell adhesion(GO:0071603)
0.4 8.0 GO:1902004 positive regulation of beta-amyloid formation(GO:1902004)
0.4 3.6 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.4 12.0 GO:0006491 N-glycan processing(GO:0006491)
0.4 1.2 GO:0000715 nucleotide-excision repair, DNA damage recognition(GO:0000715)
0.4 1.2 GO:0021693 cerebellar Purkinje cell layer structural organization(GO:0021693)
0.4 1.9 GO:0014063 negative regulation of serotonin secretion(GO:0014063)
0.4 8.1 GO:0046069 cGMP catabolic process(GO:0046069)
0.4 1.8 GO:0098971 anterograde dendritic transport of neurotransmitter receptor complex(GO:0098971)
0.4 2.8 GO:0071442 positive regulation of histone H3-K14 acetylation(GO:0071442)
0.3 1.7 GO:0051562 negative regulation of mitochondrial calcium ion concentration(GO:0051562)
0.3 8.3 GO:1901897 regulation of relaxation of cardiac muscle(GO:1901897)
0.3 1.0 GO:0070476 rRNA (guanine-N7)-methylation(GO:0070476)
0.3 1.0 GO:1904742 regulation of telomeric DNA binding(GO:1904742)
0.3 4.4 GO:0035372 protein localization to microtubule(GO:0035372)
0.3 1.2 GO:0002302 CD8-positive, alpha-beta T cell differentiation involved in immune response(GO:0002302)
0.3 1.5 GO:0061086 negative regulation of histone H3-K27 methylation(GO:0061086)
0.3 2.6 GO:0051611 regulation of serotonin uptake(GO:0051611)
0.3 0.8 GO:1904456 negative regulation of neuronal action potential(GO:1904456)
0.3 1.1 GO:0007172 signal complex assembly(GO:0007172)
0.3 1.1 GO:2000410 peripheral T cell tolerance induction(GO:0002458) peripheral tolerance induction(GO:0002465) regulation of thymocyte migration(GO:2000410)
0.3 9.9 GO:0010758 regulation of macrophage chemotaxis(GO:0010758)
0.2 0.7 GO:0035526 retrograde transport, plasma membrane to Golgi(GO:0035526)
0.2 4.1 GO:0060732 positive regulation of inositol phosphate biosynthetic process(GO:0060732)
0.2 0.7 GO:1902868 cerebral cortex GABAergic interneuron fate commitment(GO:0021893) positive regulation of neural retina development(GO:0061075) positive regulation of retina development in camera-type eye(GO:1902868) positive regulation of amacrine cell differentiation(GO:1902871)
0.2 1.7 GO:0035865 response to potassium ion(GO:0035864) cellular response to potassium ion(GO:0035865)
0.2 0.7 GO:0040040 thermosensory behavior(GO:0040040)
0.2 8.1 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.2 0.6 GO:2000793 cell proliferation involved in heart valve development(GO:2000793)
0.2 1.3 GO:0001661 conditioned taste aversion(GO:0001661)
0.2 0.8 GO:0007161 calcium-independent cell-matrix adhesion(GO:0007161)
0.2 2.9 GO:2000535 entry of bacterium into host cell(GO:0035635) regulation of entry of bacterium into host cell(GO:2000535)
0.2 2.1 GO:0055059 asymmetric neuroblast division(GO:0055059)
0.2 1.3 GO:0034651 cortisol biosynthetic process(GO:0034651)
0.2 0.5 GO:0071579 regulation of zinc ion transport(GO:0071579)
0.2 2.0 GO:0090336 positive regulation of brown fat cell differentiation(GO:0090336)
0.2 1.3 GO:0043569 negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.1 0.9 GO:2001023 regulation of response to drug(GO:2001023)
0.1 3.6 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.1 2.3 GO:0001842 neural fold formation(GO:0001842)
0.1 1.2 GO:1900122 positive regulation of receptor binding(GO:1900122)
0.1 4.2 GO:0006691 leukotriene metabolic process(GO:0006691)
0.1 0.9 GO:0061084 negative regulation of protein refolding(GO:0061084)
0.1 2.5 GO:0007250 activation of NF-kappaB-inducing kinase activity(GO:0007250)
0.1 4.8 GO:0009649 entrainment of circadian clock(GO:0009649)
0.1 0.6 GO:1904751 positive regulation of protein localization to nucleolus(GO:1904751)
0.1 0.7 GO:0021912 regulation of transcription from RNA polymerase II promoter involved in spinal cord motor neuron fate specification(GO:0021912) regulation of transcription from RNA polymerase II promoter involved in ventral spinal cord interneuron specification(GO:0021913)
0.1 1.5 GO:0048242 epinephrine secretion(GO:0048242)
0.1 0.7 GO:0060596 mammary placode formation(GO:0060596)
0.1 4.7 GO:0070884 regulation of calcineurin-NFAT signaling cascade(GO:0070884)
0.1 5.5 GO:0034243 regulation of transcription elongation from RNA polymerase II promoter(GO:0034243)
0.1 2.0 GO:0045060 negative thymic T cell selection(GO:0045060)
0.1 0.7 GO:0016185 synaptic vesicle budding from presynaptic endocytic zone membrane(GO:0016185)
0.1 0.3 GO:0072302 negative regulation of metanephric glomerulus development(GO:0072299) negative regulation of metanephric glomerular mesangial cell proliferation(GO:0072302) regulation of metanephric ureteric bud development(GO:2001074) positive regulation of metanephric ureteric bud development(GO:2001076)
0.1 0.7 GO:0098532 histone H3-K27 trimethylation(GO:0098532)
0.1 0.3 GO:0002396 MHC protein complex assembly(GO:0002396) peptide antigen assembly with MHC protein complex(GO:0002501)
0.1 0.8 GO:0070294 renal sodium ion absorption(GO:0070294)
0.1 0.9 GO:0006198 cAMP catabolic process(GO:0006198)
0.1 1.7 GO:0051152 positive regulation of smooth muscle cell differentiation(GO:0051152)
0.1 0.6 GO:0032483 regulation of Rab protein signal transduction(GO:0032483)
0.1 1.1 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.1 1.8 GO:1903818 positive regulation of voltage-gated potassium channel activity(GO:1903818)
0.1 0.7 GO:0006621 protein retention in ER lumen(GO:0006621)
0.1 0.2 GO:0010726 positive regulation of hydrogen peroxide metabolic process(GO:0010726)
0.1 0.9 GO:0033153 somatic diversification of T cell receptor genes(GO:0002568) somatic recombination of T cell receptor gene segments(GO:0002681) T cell receptor V(D)J recombination(GO:0033153)
0.1 1.9 GO:0042347 negative regulation of NF-kappaB import into nucleus(GO:0042347)
0.1 2.9 GO:0002347 response to tumor cell(GO:0002347)
0.1 3.6 GO:0007143 female meiotic division(GO:0007143)
0.1 0.4 GO:0003430 growth plate cartilage chondrocyte growth(GO:0003430)
0.1 0.5 GO:0033140 negative regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033140)
0.1 0.5 GO:0042706 eye photoreceptor cell fate commitment(GO:0042706) photoreceptor cell fate commitment(GO:0046552)
0.1 1.6 GO:0070935 3'-UTR-mediated mRNA stabilization(GO:0070935)
0.1 0.8 GO:0045654 positive regulation of megakaryocyte differentiation(GO:0045654)
0.1 4.7 GO:0006687 glycosphingolipid metabolic process(GO:0006687)
0.1 0.5 GO:0060125 negative regulation of growth hormone secretion(GO:0060125)
0.1 1.0 GO:0090043 regulation of tubulin deacetylation(GO:0090043)
0.1 0.5 GO:1903691 positive regulation of wound healing, spreading of epidermal cells(GO:1903691)
0.1 1.0 GO:0072189 ureter development(GO:0072189)
0.1 3.1 GO:0061099 negative regulation of protein tyrosine kinase activity(GO:0061099)
0.1 2.1 GO:0015985 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.1 1.1 GO:0030322 stabilization of membrane potential(GO:0030322)
0.1 2.3 GO:0061036 positive regulation of cartilage development(GO:0061036)
0.1 1.5 GO:0042297 vocal learning(GO:0042297) imitative learning(GO:0098596)
0.1 0.4 GO:2000303 regulation of ceramide biosynthetic process(GO:2000303)
0.1 0.9 GO:0019985 translesion synthesis(GO:0019985)
0.1 1.6 GO:1904355 positive regulation of telomere capping(GO:1904355)
0.1 1.3 GO:0071236 cellular response to antibiotic(GO:0071236)
0.1 1.5 GO:0042403 thyroid hormone metabolic process(GO:0042403)
0.1 0.3 GO:1901492 positive regulation of lymphangiogenesis(GO:1901492)
0.1 0.9 GO:0061162 establishment of monopolar cell polarity(GO:0061162)
0.1 0.7 GO:0007220 Notch receptor processing(GO:0007220)
0.0 1.0 GO:0035414 negative regulation of catenin import into nucleus(GO:0035414)
0.0 1.4 GO:0030575 nuclear body organization(GO:0030575)
0.0 2.8 GO:2001222 regulation of neuron migration(GO:2001222)
0.0 1.5 GO:0090036 regulation of protein kinase C signaling(GO:0090036)
0.0 0.8 GO:0030539 male genitalia development(GO:0030539)
0.0 0.8 GO:0035020 regulation of Rac protein signal transduction(GO:0035020)
0.0 0.3 GO:0018094 protein polyglycylation(GO:0018094)
0.0 0.8 GO:2000311 regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000311)
0.0 3.6 GO:0042475 odontogenesis of dentin-containing tooth(GO:0042475)
0.0 0.7 GO:0006895 Golgi to endosome transport(GO:0006895)
0.0 1.0 GO:1900452 regulation of long term synaptic depression(GO:1900452)
0.0 1.5 GO:0002053 positive regulation of mesenchymal cell proliferation(GO:0002053)
0.0 0.7 GO:0007263 nitric oxide mediated signal transduction(GO:0007263)
0.0 0.2 GO:0033132 negative regulation of glucokinase activity(GO:0033132) negative regulation of hexokinase activity(GO:1903300)
0.0 1.2 GO:0045880 positive regulation of smoothened signaling pathway(GO:0045880)
0.0 0.5 GO:0061469 regulation of type B pancreatic cell proliferation(GO:0061469)
0.0 1.3 GO:0070979 protein K11-linked ubiquitination(GO:0070979)
0.0 0.4 GO:0006301 postreplication repair(GO:0006301)
0.0 1.0 GO:0018345 protein palmitoylation(GO:0018345)
0.0 0.6 GO:0043981 histone H4-K5 acetylation(GO:0043981) histone H4-K8 acetylation(GO:0043982)
0.0 5.3 GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043123)
0.0 0.6 GO:0007190 activation of adenylate cyclase activity(GO:0007190)
0.0 0.1 GO:1903347 negative regulation of bicellular tight junction assembly(GO:1903347)
0.0 0.1 GO:0001560 regulation of cell growth by extracellular stimulus(GO:0001560)
0.0 0.2 GO:1904628 cellular response to granulocyte macrophage colony-stimulating factor stimulus(GO:0097011) response to phorbol 13-acetate 12-myristate(GO:1904627) cellular response to phorbol 13-acetate 12-myristate(GO:1904628)
0.0 0.9 GO:0032467 positive regulation of cytokinesis(GO:0032467)
0.0 0.4 GO:0002024 diet induced thermogenesis(GO:0002024)
0.0 0.7 GO:0006383 transcription from RNA polymerase III promoter(GO:0006383)
0.0 0.6 GO:0060716 labyrinthine layer blood vessel development(GO:0060716)
0.0 1.4 GO:0051298 centrosome duplication(GO:0051298)
0.0 1.4 GO:0051453 regulation of intracellular pH(GO:0051453)
0.0 2.6 GO:0007568 aging(GO:0007568)
0.0 0.8 GO:0051057 positive regulation of small GTPase mediated signal transduction(GO:0051057)
0.0 0.4 GO:1903831 acetylcholine receptor signaling pathway(GO:0095500) signal transduction involved in cellular response to ammonium ion(GO:1903831) response to acetylcholine(GO:1905144) cellular response to acetylcholine(GO:1905145)
0.0 1.8 GO:0008203 cholesterol metabolic process(GO:0008203)
0.0 0.2 GO:0021794 thalamus development(GO:0021794)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 7.8 GO:0000138 Golgi trans cisterna(GO:0000138)
0.4 1.3 GO:0042272 nuclear RNA export factor complex(GO:0042272)
0.4 1.9 GO:0043293 apoptosome(GO:0043293)
0.3 6.5 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.3 1.2 GO:0071942 XPC complex(GO:0071942)
0.3 1.9 GO:0098651 collagen type IV trimer(GO:0005587) network-forming collagen trimer(GO:0098642) collagen network(GO:0098645) basement membrane collagen trimer(GO:0098651)
0.2 2.9 GO:0032584 growth cone membrane(GO:0032584)
0.2 0.7 GO:0098830 presynaptic endosome(GO:0098830)
0.1 12.7 GO:0005793 endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)
0.1 2.1 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.1 2.0 GO:0012510 trans-Golgi network transport vesicle membrane(GO:0012510)
0.1 5.3 GO:0097440 apical dendrite(GO:0097440)
0.1 2.2 GO:0044292 dendrite terminus(GO:0044292)
0.1 1.3 GO:0048787 presynaptic active zone membrane(GO:0048787)
0.1 0.3 GO:0070449 elongin complex(GO:0070449)
0.1 1.4 GO:0071004 U2-type prespliceosome(GO:0071004)
0.1 11.6 GO:0043204 perikaryon(GO:0043204)
0.1 3.4 GO:0032809 neuronal cell body membrane(GO:0032809)
0.1 1.2 GO:0031010 ISWI-type complex(GO:0031010)
0.1 0.7 GO:0070765 gamma-secretase complex(GO:0070765)
0.1 1.5 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.1 1.6 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.1 1.8 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.1 2.4 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.0 4.1 GO:0031526 brush border membrane(GO:0031526)
0.0 4.5 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 0.9 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.0 2.0 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.0 2.5 GO:0001772 immunological synapse(GO:0001772)
0.0 0.9 GO:1902711 GABA-A receptor complex(GO:1902711)
0.0 0.7 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.0 0.8 GO:0030665 clathrin-coated vesicle membrane(GO:0030665)
0.0 0.3 GO:0042613 MHC class II protein complex(GO:0042613)
0.0 3.9 GO:0005901 caveola(GO:0005901)
0.0 2.7 GO:0016529 sarcoplasmic reticulum(GO:0016529)
0.0 1.8 GO:0008287 protein serine/threonine phosphatase complex(GO:0008287) phosphatase complex(GO:1903293)
0.0 0.6 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.0 14.7 GO:0043025 neuronal cell body(GO:0043025)
0.0 0.9 GO:0005719 nuclear euchromatin(GO:0005719)
0.0 5.3 GO:0000139 Golgi membrane(GO:0000139)
0.0 3.1 GO:0036064 ciliary basal body(GO:0036064)
0.0 1.0 GO:0045335 phagocytic vesicle(GO:0045335)
0.0 0.6 GO:0097225 sperm midpiece(GO:0097225)
0.0 0.2 GO:0002178 palmitoyltransferase complex(GO:0002178)
0.0 2.5 GO:0005902 microvillus(GO:0005902)
0.0 0.1 GO:0032444 activin responsive factor complex(GO:0032444)
0.0 3.7 GO:0008021 synaptic vesicle(GO:0008021)
0.0 1.5 GO:0042734 presynaptic membrane(GO:0042734)
0.0 4.5 GO:0005802 trans-Golgi network(GO:0005802)
0.0 0.5 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.0 1.9 GO:0032587 ruffle membrane(GO:0032587)
0.0 0.8 GO:1990391 DNA repair complex(GO:1990391)
0.0 1.0 GO:0016328 lateral plasma membrane(GO:0016328)
0.0 0.7 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 0.7 GO:0005871 kinesin complex(GO:0005871)
0.0 1.1 GO:0031234 extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.0 0.5 GO:0035097 histone methyltransferase complex(GO:0035097)
0.0 1.9 GO:0031225 anchored component of membrane(GO:0031225)
0.0 2.0 GO:0001650 fibrillar center(GO:0001650)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
2.0 5.9 GO:0031751 D4 dopamine receptor binding(GO:0031751)
1.7 6.9 GO:0008113 peptide-methionine (S)-S-oxide reductase activity(GO:0008113)
1.6 6.4 GO:0035373 chondroitin sulfate proteoglycan binding(GO:0035373)
1.3 3.8 GO:0008396 oxysterol 7-alpha-hydroxylase activity(GO:0008396)
0.9 12.0 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.6 3.7 GO:0008401 retinoic acid 4-hydroxylase activity(GO:0008401)
0.6 4.1 GO:0004991 parathyroid hormone receptor activity(GO:0004991)
0.4 1.7 GO:0035276 calcium-independent protein kinase C activity(GO:0004699) ethanol binding(GO:0035276)
0.4 3.9 GO:0005114 type II transforming growth factor beta receptor binding(GO:0005114)
0.4 3.6 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.3 1.3 GO:0070905 serine binding(GO:0070905)
0.3 1.3 GO:0008332 low voltage-gated calcium channel activity(GO:0008332)
0.3 0.9 GO:0005017 platelet-derived growth factor-activated receptor activity(GO:0005017)
0.3 14.9 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.3 8.1 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555)
0.3 3.0 GO:0008494 translation activator activity(GO:0008494)
0.3 7.5 GO:0016646 aldehyde dehydrogenase (NAD) activity(GO:0004029) oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor(GO:0016646)
0.3 3.5 GO:0070097 delta-catenin binding(GO:0070097)
0.2 0.7 GO:0016492 G-protein coupled neurotensin receptor activity(GO:0016492)
0.2 5.6 GO:0008327 methyl-CpG binding(GO:0008327)
0.2 1.3 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.2 1.0 GO:0016435 rRNA (guanine) methyltransferase activity(GO:0016435)
0.2 2.5 GO:0017154 semaphorin receptor activity(GO:0017154)
0.2 1.9 GO:0030550 acetylcholine receptor inhibitor activity(GO:0030550)
0.2 1.5 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.1 1.3 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.1 0.9 GO:0004994 somatostatin receptor activity(GO:0004994)
0.1 0.7 GO:0046923 ER retention sequence binding(GO:0046923)
0.1 2.5 GO:0003993 acid phosphatase activity(GO:0003993)
0.1 1.5 GO:0051378 serotonin binding(GO:0051378)
0.1 2.0 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.1 3.1 GO:0008171 O-methyltransferase activity(GO:0008171)
0.1 3.3 GO:0097602 cullin family protein binding(GO:0097602)
0.1 4.4 GO:0008483 transaminase activity(GO:0008483)
0.1 1.3 GO:0034046 poly(G) binding(GO:0034046)
0.1 2.5 GO:0005161 platelet-derived growth factor receptor binding(GO:0005161)
0.1 2.0 GO:0048406 nerve growth factor binding(GO:0048406)
0.1 2.1 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.1 0.6 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.1 2.5 GO:0004707 MAP kinase activity(GO:0004707)
0.1 0.3 GO:0004968 gonadotropin-releasing hormone receptor activity(GO:0004968)
0.1 0.9 GO:0005519 cytoskeletal regulatory protein binding(GO:0005519)
0.1 8.0 GO:0035064 methylated histone binding(GO:0035064)
0.1 0.7 GO:0031821 G-protein coupled serotonin receptor binding(GO:0031821)
0.1 6.8 GO:0001540 beta-amyloid binding(GO:0001540)
0.1 5.9 GO:0019213 deacetylase activity(GO:0019213)
0.1 1.4 GO:0005522 profilin binding(GO:0005522)
0.1 3.7 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.1 0.3 GO:0010385 double-stranded methylated DNA binding(GO:0010385) hemi-methylated DNA-binding(GO:0044729)
0.1 2.5 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.1 1.3 GO:0032794 GTPase activating protein binding(GO:0032794)
0.1 1.2 GO:0070679 inositol 1,4,5 trisphosphate binding(GO:0070679)
0.1 1.4 GO:0050321 tau-protein kinase activity(GO:0050321)
0.1 0.6 GO:0043995 histone acetyltransferase activity (H4-K5 specific)(GO:0043995) histone acetyltransferase activity (H4-K8 specific)(GO:0043996) histone acetyltransferase activity (H4-K16 specific)(GO:0046972)
0.1 0.6 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.1 0.4 GO:0004645 phosphorylase activity(GO:0004645)
0.1 3.0 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.1 1.8 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.1 0.4 GO:0033188 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.1 1.4 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.1 2.0 GO:0005242 inward rectifier potassium channel activity(GO:0005242)
0.1 1.1 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.1 0.3 GO:0070736 protein-glycine ligase activity, initiating(GO:0070736)
0.1 3.0 GO:0030332 cyclin binding(GO:0030332)
0.1 1.0 GO:0046030 inositol-polyphosphate 5-phosphatase activity(GO:0004445) inositol trisphosphate phosphatase activity(GO:0046030)
0.1 1.2 GO:0030957 Tat protein binding(GO:0030957)
0.1 0.7 GO:0015379 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.1 5.9 GO:0030971 receptor tyrosine kinase binding(GO:0030971)
0.1 0.7 GO:0000182 rDNA binding(GO:0000182)
0.1 0.2 GO:0050262 ribosylnicotinamide kinase activity(GO:0050262) ribosylnicotinate kinase activity(GO:0061769)
0.1 0.4 GO:0004969 histamine receptor activity(GO:0004969)
0.0 3.7 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.0 0.7 GO:0032050 clathrin heavy chain binding(GO:0032050)
0.0 1.8 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.0 0.6 GO:0004016 adenylate cyclase activity(GO:0004016)
0.0 0.5 GO:0045499 chemorepellent activity(GO:0045499)
0.0 2.9 GO:0043022 ribosome binding(GO:0043022)
0.0 1.3 GO:0070330 aromatase activity(GO:0070330)
0.0 1.1 GO:0008432 JUN kinase binding(GO:0008432)
0.0 1.1 GO:0045182 translation regulator activity(GO:0045182)
0.0 0.7 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.0 2.1 GO:0005249 voltage-gated potassium channel activity(GO:0005249)
0.0 0.5 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.0 0.9 GO:0004890 GABA-A receptor activity(GO:0004890)
0.0 1.0 GO:0019706 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 0.9 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 0.4 GO:0003708 retinoic acid receptor activity(GO:0003708)
0.0 0.4 GO:0070700 BMP receptor binding(GO:0070700)
0.0 3.0 GO:0020037 heme binding(GO:0020037)
0.0 1.6 GO:0048487 beta-tubulin binding(GO:0048487)
0.0 1.2 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
0.0 4.4 GO:0008757 S-adenosylmethionine-dependent methyltransferase activity(GO:0008757)
0.0 1.3 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.0 9.8 GO:0005096 GTPase activator activity(GO:0005096)
0.0 0.2 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.0 1.1 GO:0005158 insulin receptor binding(GO:0005158)
0.0 1.2 GO:0003684 damaged DNA binding(GO:0003684)
0.0 2.3 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.8 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 0.5 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0 0.7 GO:0003899 DNA-directed RNA polymerase activity(GO:0003899)
0.0 1.2 GO:0001085 RNA polymerase II transcription factor binding(GO:0001085)
0.0 5.6 GO:0004175 endopeptidase activity(GO:0004175)
0.0 0.8 GO:0002039 p53 binding(GO:0002039)
0.0 0.6 GO:0070888 E-box binding(GO:0070888)
0.0 0.2 GO:0004017 adenylate kinase activity(GO:0004017)
0.0 0.1 GO:0005072 transforming growth factor beta receptor, cytoplasmic mediator activity(GO:0005072) sulfate binding(GO:0043199)
0.0 0.4 GO:0051879 Hsp90 protein binding(GO:0051879)
0.0 2.9 GO:0001047 core promoter binding(GO:0001047)
0.0 4.8 GO:0045296 cadherin binding(GO:0045296)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 13.0 ST WNT CA2 CYCLIC GMP PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.2 3.9 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.1 9.0 PID HNF3A PATHWAY FOXA1 transcription factor network
0.1 10.1 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.1 2.3 PID LPA4 PATHWAY LPA4-mediated signaling events
0.1 4.7 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.1 6.6 PID RHOA REG PATHWAY Regulation of RhoA activity
0.1 6.7 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.1 5.3 PID AMB2 NEUTROPHILS PATHWAY amb2 Integrin signaling
0.1 4.5 PID RHOA PATHWAY RhoA signaling pathway
0.1 2.0 PID NECTIN PATHWAY Nectin adhesion pathway
0.1 0.5 PID AVB3 INTEGRIN PATHWAY Integrins in angiogenesis
0.1 2.9 PID ARF6 TRAFFICKING PATHWAY Arf6 trafficking events
0.0 1.3 PID BARD1 PATHWAY BARD1 signaling events
0.0 2.3 PID FANCONI PATHWAY Fanconi anemia pathway
0.0 4.8 PID NOTCH PATHWAY Notch signaling pathway
0.0 0.7 PID S1P S1P4 PATHWAY S1P4 pathway
0.0 1.9 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.0 1.5 PID LKB1 PATHWAY LKB1 signaling events
0.0 3.4 PID MTOR 4PATHWAY mTOR signaling pathway
0.0 2.3 PID CERAMIDE PATHWAY Ceramide signaling pathway
0.0 0.7 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.0 1.2 PID CD8 TCR DOWNSTREAM PATHWAY Downstream signaling in naïve CD8+ T cells
0.0 0.9 PID REELIN PATHWAY Reelin signaling pathway
0.0 1.1 PID RET PATHWAY Signaling events regulated by Ret tyrosine kinase
0.0 0.4 PID RETINOIC ACID PATHWAY Retinoic acid receptors-mediated signaling
0.0 1.3 PID TELOMERASE PATHWAY Regulation of Telomerase
0.0 0.6 PID HIF2PATHWAY HIF-2-alpha transcription factor network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 5.1 REACTOME ENDOGENOUS STEROLS Genes involved in Endogenous sterols
0.2 8.1 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.2 7.0 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.2 3.7 REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.2 1.5 REACTOME SEROTONIN RECEPTORS Genes involved in Serotonin receptors
0.1 2.8 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.1 3.9 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.1 2.0 REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.1 1.2 REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.1 5.9 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.1 2.3 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.1 2.1 REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.1 5.9 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.1 1.4 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.1 2.3 REACTOME DAG AND IP3 SIGNALING Genes involved in DAG and IP3 signaling
0.1 17.7 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.1 1.3 REACTOME ACYL CHAIN REMODELLING OF PS Genes involved in Acyl chain remodelling of PS
0.1 1.1 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.1 1.3 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.1 1.3 REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.1 1.8 REACTOME KINESINS Genes involved in Kinesins
0.1 0.7 REACTOME SIGNALING BY NOTCH2 Genes involved in Signaling by NOTCH2
0.0 1.2 REACTOME FORMATION OF INCISION COMPLEX IN GG NER Genes involved in Formation of incision complex in GG-NER
0.0 1.8 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0 12.2 REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES Genes involved in Metabolism of amino acids and derivatives
0.0 0.7 REACTOME PLC BETA MEDIATED EVENTS Genes involved in PLC beta mediated events
0.0 0.9 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.0 1.3 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.0 1.1 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.0 1.3 REACTOME METAL ION SLC TRANSPORTERS Genes involved in Metal ion SLC transporters
0.0 0.5 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.0 1.5 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0 1.0 REACTOME P75 NTR RECEPTOR MEDIATED SIGNALLING Genes involved in p75 NTR receptor-mediated signalling
0.0 0.8 REACTOME MEIOTIC RECOMBINATION Genes involved in Meiotic Recombination
0.0 0.8 REACTOME TRAFFICKING OF AMPA RECEPTORS Genes involved in Trafficking of AMPA receptors
0.0 0.6 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 0.4 REACTOME AMINE LIGAND BINDING RECEPTORS Genes involved in Amine ligand-binding receptors
0.0 2.0 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0 0.2 REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.0 0.2 REACTOME FGFR4 LIGAND BINDING AND ACTIVATION Genes involved in FGFR4 ligand binding and activation