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GSE58827: Dynamics of the Mouse Liver

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Results for Klf8

Z-value: 0.87

Motif logo

Transcription factors associated with Klf8

Gene Symbol Gene ID Gene Info
ENSMUSG00000041649.14 Kruppel-like factor 8

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Klf8mm39_v1_chrX_+_152020744_152020838-0.173.2e-01Click!

Activity profile of Klf8 motif

Sorted Z-values of Klf8 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr11_+_83637766 3.39 ENSMUST00000070832.3
WAP four-disulfide core domain 21
chr19_-_6117815 1.76 ENSMUST00000162575.8
ENSMUST00000159084.8
ENSMUST00000161718.8
ENSMUST00000162810.8
ENSMUST00000025713.12
ENSMUST00000113543.9
ENSMUST00000160417.8
ENSMUST00000161528.2
transmembrane 7 superfamily member 2
chr10_+_79716876 1.73 ENSMUST00000166201.2
proteinase 3
chrX_-_7834057 1.72 ENSMUST00000033502.14
GATA binding protein 1
chr7_-_30623592 1.48 ENSMUST00000217812.2
ENSMUST00000074671.9
hepcidin antimicrobial peptide 2
chr7_-_126625657 1.44 ENSMUST00000205568.2
MYC-associated zinc finger protein (purine-binding transcription factor)
chr7_-_126625617 1.21 ENSMUST00000032916.6
MYC-associated zinc finger protein (purine-binding transcription factor)
chr11_+_32236945 1.16 ENSMUST00000101387.4
hemoglobin, theta 1B
chr2_-_32271833 1.13 ENSMUST00000146423.2
RIKEN cDNA 1110008P14 gene
chr7_-_127529238 1.07 ENSMUST00000032988.10
ENSMUST00000206124.2
protease, serine 8 (prostasin)
chr7_-_28947882 1.06 ENSMUST00000032808.6
RIKEN cDNA 2200002D01 gene
chr11_-_5900019 1.06 ENSMUST00000102920.4
glucokinase
chr7_+_24584076 1.05 ENSMUST00000153451.9
ENSMUST00000108429.8
ribosomal protein S19
chr10_+_75399920 1.00 ENSMUST00000141062.8
ENSMUST00000152657.8
gamma-glutamyltransferase 1
chr19_+_6952580 0.95 ENSMUST00000237084.2
ENSMUST00000236218.2
ENSMUST00000237235.2
protein phosphatase 1, regulatory inhibitor subunit 14B
chr14_-_30850795 0.94 ENSMUST00000049732.11
ENSMUST00000090205.5
ENSMUST00000064032.10
small integral membrane protein 4
chr17_+_29487881 0.92 ENSMUST00000234845.2
ENSMUST00000235038.2
ENSMUST00000235050.2
ENSMUST00000120346.9
ENSMUST00000234377.2
ENSMUST00000235074.2
ENSMUST00000235040.2
ENSMUST00000234256.2
ENSMUST00000234459.2
cDNA sequence BC004004
chr6_-_72935171 0.91 ENSMUST00000114049.2
thymosin, beta 10
chr19_+_6952319 0.91 ENSMUST00000070850.8
protein phosphatase 1, regulatory inhibitor subunit 14B
chr7_-_27055405 0.90 ENSMUST00000003857.7
Sh3kbp1 binding protein 1
chr15_+_78810919 0.88 ENSMUST00000089377.6
lectin, galactose binding, soluble 1
chr9_-_21202353 0.87 ENSMUST00000086374.8
cyclin dependent kinase inhibitor 2D
chr7_-_103477126 0.86 ENSMUST00000023934.8
hemoglobin, beta adult s chain
chr9_-_21202545 0.85 ENSMUST00000215619.2
cyclin dependent kinase inhibitor 2D
chr4_-_43040278 0.84 ENSMUST00000107958.8
ENSMUST00000107959.8
ENSMUST00000152846.8
family with sequence similarity 214, member B
chr8_-_105991219 0.83 ENSMUST00000034359.10
TNFRSF1A-associated via death domain
chr2_-_29983618 0.83 ENSMUST00000081838.7
ENSMUST00000102865.11
zinc finger, DHHC domain containing 12
chr14_-_70864448 0.82 ENSMUST00000110984.4
dematin actin binding protein
chr7_+_24583994 0.82 ENSMUST00000108428.8
ribosomal protein S19
chr17_-_57554631 0.80 ENSMUST00000233568.2
ENSMUST00000005975.8
G protein-coupled receptor 108
chr8_+_23464860 0.79 ENSMUST00000110688.9
ENSMUST00000121802.9
ankyrin 1, erythroid
chr17_+_29487762 0.79 ENSMUST00000064709.13
ENSMUST00000234711.2
cDNA sequence BC004004
chr6_+_124908389 0.77 ENSMUST00000180095.4
myeloid leukemia factor 2
chr19_+_5540483 0.77 ENSMUST00000209469.2
ENSMUST00000116560.3
cofilin 1, non-muscle
chr2_-_164197987 0.76 ENSMUST00000165980.2
secretory leukocyte peptidase inhibitor
chr7_+_126294527 0.76 ENSMUST00000130498.2
bolA-like 2 (E. coli)
chr10_-_80426125 0.74 ENSMUST00000187646.2
ENSMUST00000191440.7
ENSMUST00000003436.12
abhydrolase domain containing 17A
chr12_+_109418759 0.71 ENSMUST00000056110.15
delta like non-canonical Notch ligand 1
chr17_-_24915121 0.70 ENSMUST00000046839.10
growth factor, augmenter of liver regeneration
chr2_-_164198427 0.70 ENSMUST00000109367.10
secretory leukocyte peptidase inhibitor
chr7_+_28988724 0.68 ENSMUST00000207714.2
ENSMUST00000048187.6
protein phosphatase 1, regulatory inhibitor subunit 14A
chr18_-_34505544 0.67 ENSMUST00000236887.2
receptor accessory protein 5
chr15_+_78290896 0.67 ENSMUST00000167140.8
mercaptopyruvate sulfurtransferase
chr5_+_31205971 0.66 ENSMUST00000013766.13
ENSMUST00000201773.4
ENSMUST00000200748.4
ENSMUST00000201136.2
all-trans retinoic acid induced differentiation factor
chr16_+_17884267 0.65 ENSMUST00000151266.8
ENSMUST00000066027.14
ENSMUST00000155387.8
DiGeorge syndrome critical region gene 6
chr9_-_21202693 0.64 ENSMUST00000213407.2
cyclin dependent kinase inhibitor 2D
chr17_-_34219225 0.64 ENSMUST00000238098.2
ENSMUST00000087189.7
ENSMUST00000173075.3
ENSMUST00000172912.8
ENSMUST00000236740.2
ENSMUST00000025181.18
histocompatibility 2, K1, K region
chr19_+_5540591 0.63 ENSMUST00000237122.2
cofilin 1, non-muscle
chr2_-_38534099 0.62 ENSMUST00000028083.6
proteasome (prosome, macropain) subunit, beta type 7
chr8_+_105991280 0.61 ENSMUST00000036221.12
F-box and leucine-rich repeat protein 8
chr17_+_35117905 0.61 ENSMUST00000097342.10
ENSMUST00000013931.12
euchromatic histone lysine N-methyltransferase 2
chr9_-_114610879 0.61 ENSMUST00000084867.9
ENSMUST00000216760.2
ENSMUST00000035009.16
CKLF-like MARVEL transmembrane domain containing 7
chr6_+_124908439 0.61 ENSMUST00000032214.14
myeloid leukemia factor 2
chrX_-_72965524 0.60 ENSMUST00000114389.10
N(alpha)-acetyltransferase 10, NatA catalytic subunit
chr1_+_135945705 0.59 ENSMUST00000063719.15
transmembrane protein 9
chr7_-_45750050 0.58 ENSMUST00000209291.2
potassium inwardly rectifying channel, subfamily J, member 11
chr1_+_135746330 0.57 ENSMUST00000038760.10
ladinin
chr15_+_78290975 0.57 ENSMUST00000043865.8
ENSMUST00000231159.2
ENSMUST00000169133.8
mercaptopyruvate sulfurtransferase
chr17_-_46956920 0.56 ENSMUST00000233974.2
kinesin light chain 4
chrX_-_72965434 0.55 ENSMUST00000096316.4
ENSMUST00000114390.8
ENSMUST00000114391.10
ENSMUST00000114387.8
N(alpha)-acetyltransferase 10, NatA catalytic subunit
chr1_+_135945798 0.53 ENSMUST00000117950.2
transmembrane protein 9
chr13_+_120151982 0.52 ENSMUST00000179869.3
ENSMUST00000224188.2
3-hydroxy-3-methylglutaryl-Coenzyme A synthase 1
chr15_+_100768551 0.52 ENSMUST00000082209.13
sodium channel, voltage-gated, type VIII, alpha
chr13_+_73476629 0.51 ENSMUST00000221730.2
mitochondrial ribosomal protein L36
chr17_-_26014613 0.50 ENSMUST00000235889.2
predicted gene, 50367
chrX_-_72965536 0.50 ENSMUST00000033763.15
N(alpha)-acetyltransferase 10, NatA catalytic subunit
chr17_+_35117438 0.50 ENSMUST00000114033.9
ENSMUST00000078061.13
euchromatic histone lysine N-methyltransferase 2
chr2_+_143757193 0.49 ENSMUST00000103172.4
destrin
chr4_+_127062924 0.48 ENSMUST00000046659.14
DLG associated protein 3
chr5_+_115373895 0.47 ENSMUST00000081497.13
processing of precursor 5, ribonuclease P/MRP family (S. cerevisiae)
chr7_+_28937746 0.47 ENSMUST00000108238.8
ENSMUST00000032809.10
Yip1 interacting factor homolog B (S. cerevisiae)
chr11_-_88608958 0.47 ENSMUST00000107908.2
musashi RNA-binding protein 2
chr12_-_118265163 0.46 ENSMUST00000221844.2
trans-acting transcription factor 4
chr11_+_120489358 0.45 ENSMUST00000093140.5
anaphase promoting complex subunit 11
chr2_+_122479770 0.45 ENSMUST00000047498.15
ENSMUST00000110512.4
expressed sequence AA467197
chr19_+_6547790 0.45 ENSMUST00000113458.8
ENSMUST00000113459.2
neurexin II
chr13_+_108452930 0.44 ENSMUST00000171178.2
DEP domain containing 1B
chr14_-_30850881 0.44 ENSMUST00000203261.3
small integral membrane protein 4
chr17_+_46957151 0.44 ENSMUST00000002844.14
ENSMUST00000113429.8
ENSMUST00000113430.2
mitochondrial ribosomal protein L2
chr2_-_90735171 0.43 ENSMUST00000005647.4
NADH:ubiquinone oxidoreductase core subunit S3
chr14_-_55828511 0.43 ENSMUST00000161807.8
ENSMUST00000111378.10
ENSMUST00000159687.2
proteasome (prosome, macropain) activator subunit 2 (PA28 beta)
chr5_+_31079177 0.42 ENSMUST00000031053.15
ENSMUST00000202752.2
ketohexokinase
chrX_+_93278203 0.41 ENSMUST00000153900.8
kelch-like 15
chr15_-_75439013 0.41 ENSMUST00000156032.2
ENSMUST00000127095.8
lymphocyte antigen 6 complex, locus H
chr11_+_70548022 0.41 ENSMUST00000157027.8
ENSMUST00000072841.12
ENSMUST00000108548.8
ENSMUST00000126241.8
enolase 3, beta muscle
chr11_-_115310743 0.41 ENSMUST00000106537.8
ENSMUST00000043931.9
ENSMUST00000073791.10
ATP synthase, H+ transporting, mitochondrial F0 complex, subunit D
chr9_+_114807546 0.41 ENSMUST00000183104.8
oxysterol binding protein-like 10
chr15_-_89258034 0.40 ENSMUST00000228977.2
SCO2 cytochrome c oxidase assembly protein
chr19_+_6919691 0.40 ENSMUST00000113426.8
ENSMUST00000238184.2
ENSMUST00000113423.10
ENSMUST00000237334.2
ENSMUST00000235240.2
BCL2-associated agonist of cell death
chrX_+_74460275 0.39 ENSMUST00000118428.8
ENSMUST00000114074.8
ENSMUST00000133781.8
BRCA1/BRCA2-containing complex, subunit 3
chr2_-_122199604 0.39 ENSMUST00000151130.8
Src homology 2 domain containing F
chr15_-_89258012 0.39 ENSMUST00000167643.4
SCO2 cytochrome c oxidase assembly protein
chr1_+_172327569 0.39 ENSMUST00000111230.8
transgelin 2
chr7_+_64151838 0.38 ENSMUST00000205604.2
amyloid beta (A4) precursor protein-binding, family A, member 2
chr5_+_31078911 0.38 ENSMUST00000201571.4
ketohexokinase
chr4_+_109264284 0.38 ENSMUST00000064129.14
ENSMUST00000106619.8
tetratricopeptide repeat domain 39A
chr8_+_73449907 0.38 ENSMUST00000109950.5
ENSMUST00000004494.16
ENSMUST00000212095.2
ENSMUST00000212096.2
transcriptional regulator, SIN3B (yeast)
chr3_+_90448453 0.38 ENSMUST00000107333.8
ENSMUST00000107331.8
ENSMUST00000098910.3
S100 calcium binding protein A16
chr11_-_69838971 0.38 ENSMUST00000179298.3
ENSMUST00000018710.13
ENSMUST00000135437.3
ENSMUST00000141837.9
ENSMUST00000142500.8
solute carrier family 2 (facilitated glucose transporter), member 4
chr17_-_71158703 0.38 ENSMUST00000166395.9
TGFB-induced factor homeobox 1
chr9_+_108765701 0.37 ENSMUST00000026743.14
ENSMUST00000194047.3
ubiquinol-cytochrome c reductase core protein 1
chr5_+_139777263 0.37 ENSMUST00000018287.10
v-maf musculoaponeurotic fibrosarcoma oncogene family, protein K (avian)
chr12_-_69274936 0.37 ENSMUST00000221411.2
ENSMUST00000021359.7
polymerase (DNA directed), epsilon 2 (p59 subunit)
chr5_+_32616566 0.36 ENSMUST00000202078.2
protein phosphatase 1 catalytic subunit beta
chr7_-_30754792 0.36 ENSMUST00000206328.2
FXYD domain-containing ion transport regulator 1
chr7_-_30755007 0.36 ENSMUST00000206474.2
ENSMUST00000205807.2
ENSMUST00000039909.13
ENSMUST00000206305.2
ENSMUST00000205439.2
FXYD domain-containing ion transport regulator 1
chr16_-_18630365 0.35 ENSMUST00000096990.10
cell division cycle 45
chr7_-_3551003 0.34 ENSMUST00000065703.9
ENSMUST00000203020.3
ENSMUST00000203821.3
T cell-interacting, activating receptor on myeloid cells 1
chr1_+_190830522 0.34 ENSMUST00000027943.6
basic leucine zipper transcription factor, ATF-like 3
chr7_-_19133783 0.34 ENSMUST00000047170.10
ENSMUST00000108459.9
kinesin light chain 3
chr4_-_150998857 0.34 ENSMUST00000105675.8
Parkinson disease (autosomal recessive, early onset) 7
chr12_-_103597663 0.34 ENSMUST00000121625.2
ENSMUST00000044231.12
serine (or cysteine) peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10
chr7_+_28151370 0.33 ENSMUST00000190954.7
leucine rich repeat and fibronectin type III domain containing 1
chr8_+_94537910 0.33 ENSMUST00000138659.9
guanine nucleotide binding protein, alpha O
chr5_-_123270449 0.33 ENSMUST00000186469.7
ras homolog family member F (in filopodia)
chr13_-_43324824 0.32 ENSMUST00000220787.2
TBC1 domain family, member 7
chr5_+_129924564 0.32 ENSMUST00000041466.14
zinc finger, BED type containing 5
chr2_+_156681991 0.31 ENSMUST00000073352.10
TGFB-induced factor homeobox 2
chr8_-_64659004 0.31 ENSMUST00000066166.6
tolloid-like
chrX_-_72703330 0.31 ENSMUST00000114473.8
ENSMUST00000002087.14
pregnancy upregulated non-ubiquitously expressed CaM kinase
chrX_-_50294867 0.30 ENSMUST00000114876.9
muscleblind like splicing factor 3
chr12_+_71063431 0.30 ENSMUST00000125125.2
AT rich interactive domain 4A (RBP1-like)
chrX_+_74460234 0.30 ENSMUST00000033544.14
BRCA1/BRCA2-containing complex, subunit 3
chr14_+_54713557 0.30 ENSMUST00000164766.8
rad and gem related GTP binding protein 2
chr11_-_62539284 0.30 ENSMUST00000057194.9
leucine rich repeat containing 75A
chr5_-_123270702 0.30 ENSMUST00000031401.6
ras homolog family member F (in filopodia)
chr11_-_67812960 0.29 ENSMUST00000021288.10
ENSMUST00000108677.2
ubiquitin specific peptidase 43
chr11_-_88609048 0.29 ENSMUST00000107909.8
musashi RNA-binding protein 2
chr18_+_62086122 0.29 ENSMUST00000051720.6
ENSMUST00000235860.2
SH3 domain and tetratricopeptide repeats 2
chr4_-_128699838 0.29 ENSMUST00000106072.9
ENSMUST00000170934.3
zinc finger protein 362
chr11_-_102837514 0.28 ENSMUST00000057849.6
complement component 1, q subcomponent-like 1
chr15_+_79999643 0.28 ENSMUST00000135727.2
synaptogyrin 1
chr9_-_45847344 0.28 ENSMUST00000034590.4
transgelin
chr11_+_72889889 0.28 ENSMUST00000021141.14
purinergic receptor P2X, ligand-gated ion channel, 1
chr16_+_93480061 0.28 ENSMUST00000039620.7
carbonyl reductase 3
chr17_+_23879448 0.27 ENSMUST00000062967.10
BICD family like cargo adaptor 2
chr9_-_44199626 0.27 ENSMUST00000161408.2
ATP binding cassette subfamily G member 4
chrX_+_7750483 0.26 ENSMUST00000115663.10
ENSMUST00000096514.11
solute carrier family 35 (UDP-galactose transporter), member A2
chr1_-_106641940 0.26 ENSMUST00000112751.2
B cell leukemia/lymphoma 2
chr9_-_31824758 0.26 ENSMUST00000116615.5
BarH-like homeobox 2
chr8_+_94537460 0.26 ENSMUST00000034198.15
ENSMUST00000125716.8
guanine nucleotide binding protein, alpha O
chr2_-_52566583 0.25 ENSMUST00000178799.8
calcium channel, voltage-dependent, beta 4 subunit
chr2_+_156681927 0.25 ENSMUST00000081335.13
TGFB-induced factor homeobox 2
chr4_-_155127601 0.25 ENSMUST00000135665.9
phospholipase C, eta 2
chr6_-_136150491 0.25 ENSMUST00000111905.8
ENSMUST00000152012.8
ENSMUST00000143943.8
ENSMUST00000125905.2
glutamate receptor, ionotropic, NMDA2B (epsilon 2)
chr7_+_28937898 0.25 ENSMUST00000138128.3
ENSMUST00000142519.3
Yip1 interacting factor homolog B (S. cerevisiae)
chr11_-_120538928 0.25 ENSMUST00000239158.2
ENSMUST00000026134.3
myeloid-associated differentiation marker-like 2
chr11_-_86574586 0.25 ENSMUST00000018315.10
vacuole membrane protein 1
chrX_+_7439839 0.25 ENSMUST00000144719.9
ENSMUST00000234896.2
Foxp3 regulating long intergenic noncoding RNA
forkhead box P3
chr8_+_86026318 0.24 ENSMUST00000170141.3
ENSMUST00000034132.13
origin recognition complex, subunit 6
chr4_+_129384983 0.24 ENSMUST00000106043.3
family with sequence similarity 229, member A
chr2_-_168583670 0.24 ENSMUST00000029060.11
ATPase, class II, type 9A
chr10_-_90959853 0.24 ENSMUST00000170810.8
ENSMUST00000076694.13
solute carrier family 25 (mitochondrial carrier, phosphate carrier), member 3
chr13_-_99584091 0.24 ENSMUST00000223725.2
microtubule-associated protein 1B
chr4_-_130068902 0.24 ENSMUST00000105998.8
tubulointerstitial nephritis antigen-like 1
chrX_+_73298342 0.23 ENSMUST00000096424.11
emerin
chr18_+_84738144 0.23 ENSMUST00000161429.3
ENSMUST00000052501.8
divergent protein kinase domain 1C
chr8_+_114932312 0.23 ENSMUST00000049509.7
ENSMUST00000150963.2
vesicle amine transport protein 1 like
chr11_+_70548513 0.23 ENSMUST00000134087.8
enolase 3, beta muscle
chr9_-_44199428 0.23 ENSMUST00000160384.2
ATP binding cassette subfamily G member 4
chr5_+_122347792 0.22 ENSMUST00000072602.14
hydrogen voltage-gated channel 1
chr7_+_25005510 0.22 ENSMUST00000119703.8
ENSMUST00000205639.3
ENSMUST00000108409.2
transmembrane protein 145
chr12_-_79343040 0.22 ENSMUST00000218377.2
ENSMUST00000021547.8
zinc finger, FYVE domain containing 26
chr10_-_90959817 0.22 ENSMUST00000164505.2
solute carrier family 25 (mitochondrial carrier, phosphate carrier), member 3
chr14_-_47025724 0.21 ENSMUST00000146629.3
ENSMUST00000015903.12
cornichon family AMPA receptor auxiliary protein 1
chr6_-_52185674 0.21 ENSMUST00000062829.9
homeobox A6
chr11_-_101357046 0.21 ENSMUST00000040430.8
vesicle amine transport 1
chr7_-_136915602 0.21 ENSMUST00000210774.2
early B cell factor 3
chr3_+_129007599 0.21 ENSMUST00000042587.12
paired-like homeodomain transcription factor 2
chr6_+_124908341 0.21 ENSMUST00000203021.3
myeloid leukemia factor 2
chr19_-_5962798 0.21 ENSMUST00000118623.2
D4, zinc and double PHD fingers family 2
chr2_-_26096547 0.21 ENSMUST00000028302.8
LIM homeobox protein 3
chr11_-_45835737 0.20 ENSMUST00000129820.8
U7 snRNP-specific Sm-like protein LSM11
chr11_+_69945157 0.20 ENSMUST00000108585.9
ENSMUST00000018699.13
asialoglycoprotein receptor 1
chr7_+_64151435 0.20 ENSMUST00000032732.15
amyloid beta (A4) precursor protein-binding, family A, member 2
chr13_+_55517545 0.20 ENSMUST00000063771.14
regulator of G-protein signaling 14
chrX_-_50294652 0.20 ENSMUST00000114875.8
muscleblind like splicing factor 3
chr5_+_147206769 0.20 ENSMUST00000085591.7
pancreatic and duodenal homeobox 1
chr3_+_96543143 0.20 ENSMUST00000165842.3
peroxisomal biogenesis factor 11 beta
chr17_+_25992761 0.20 ENSMUST00000237541.2
cytosolic iron-sulfur assembly component 3
chr17_-_37523969 0.20 ENSMUST00000060728.7
ENSMUST00000216318.2
olfactory receptor 95
chr16_+_20448547 0.19 ENSMUST00000003898.12
ENSMUST00000122306.8
ENSMUST00000133344.8
endothelin converting enzyme 2
chr19_+_45991907 0.19 ENSMUST00000099393.4
HPS6, biogenesis of lysosomal organelles complex 2 subunit 3
chr13_-_114595122 0.19 ENSMUST00000231252.2
follistatin
chr2_-_91540864 0.19 ENSMUST00000028678.9
ENSMUST00000076803.12
autophagy related 13
chr8_+_107237483 0.19 ENSMUST00000080797.8
cadherin 3
chr4_-_49845549 0.18 ENSMUST00000093859.11
ENSMUST00000076674.4
glutamate receptor ionotropic, NMDA3A
chr1_+_158190090 0.18 ENSMUST00000194369.6
ENSMUST00000195311.6
astrotactin 1
chrX_+_161543384 0.18 ENSMUST00000033720.12
ENSMUST00000112327.8
retinoblastoma binding protein 7, chromatin remodeling factor
chr4_-_56990306 0.18 ENSMUST00000053681.6
ferric-chelate reductase 1 like
chr7_-_142522995 0.18 ENSMUST00000009392.6
achaete-scute family bHLH transcription factor 2
chrX_+_72800675 0.18 ENSMUST00000002079.7
plexin B3
chrX_+_56008685 0.17 ENSMUST00000096431.10
adhesion G protein-coupled receptor G4
chr15_-_79976016 0.17 ENSMUST00000185306.3
ribosomal protein L3
chr14_+_54713703 0.17 ENSMUST00000164697.8
rad and gem related GTP binding protein 2
chr17_-_71158184 0.17 ENSMUST00000059775.15
TGFB-induced factor homeobox 1
chr11_-_28533995 0.17 ENSMUST00000146385.9
coiled-coil domain containing 85A
chr7_+_28937859 0.17 ENSMUST00000108237.2
Yip1 interacting factor homolog B (S. cerevisiae)
chr2_+_128971620 0.17 ENSMUST00000035481.5
coiled-coil-helix-coiled-coil-helix domain containing 5
chr11_+_115310885 0.17 ENSMUST00000103035.10
potassium channel tetramerisation domain containing 2

Network of associatons between targets according to the STRING database.

First level regulatory network of Klf8

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.7 GO:0030221 basophil differentiation(GO:0030221)
0.5 1.9 GO:0060265 positive regulation of respiratory burst involved in inflammatory response(GO:0060265)
0.5 1.4 GO:1904783 positive regulation of NMDA glutamate receptor activity(GO:1904783) regulation of establishment or maintenance of cell polarity regulating cell shape(GO:2000769) positive regulation of establishment or maintenance of cell polarity regulating cell shape(GO:2000771)
0.4 1.5 GO:0034757 negative regulation of iron ion transport(GO:0034757) negative regulation of iron ion transmembrane transport(GO:0034760)
0.3 1.7 GO:0097029 mature conventional dendritic cell differentiation(GO:0097029)
0.3 0.9 GO:0034117 erythrocyte aggregation(GO:0034117) regulation of erythrocyte aggregation(GO:0034118)
0.3 1.1 GO:0071314 cellular response to cocaine(GO:0071314)
0.3 1.3 GO:0034287 detection of carbohydrate stimulus(GO:0009730) detection of hexose stimulus(GO:0009732) detection of monosaccharide stimulus(GO:0034287) detection of glucose(GO:0051594)
0.2 2.7 GO:0006369 termination of RNA polymerase II transcription(GO:0006369)
0.2 1.6 GO:0017198 N-terminal peptidyl-serine acetylation(GO:0017198) N-terminal peptidyl-glutamic acid acetylation(GO:0018002) peptidyl-serine acetylation(GO:0030920)
0.2 0.8 GO:0009744 response to sucrose(GO:0009744) response to disaccharide(GO:0034285)
0.2 0.7 GO:0070537 histone H2A K63-linked deubiquitination(GO:0070537)
0.2 2.4 GO:0048102 autophagic cell death(GO:0048102)
0.2 0.6 GO:0002337 B-1a B cell differentiation(GO:0002337)
0.1 1.7 GO:1901727 positive regulation of histone deacetylase activity(GO:1901727)
0.1 0.8 GO:0035585 calcium-mediated signaling using extracellular calcium source(GO:0035585)
0.1 0.4 GO:1902220 positive regulation of intrinsic apoptotic signaling pathway in response to osmotic stress(GO:1902220)
0.1 0.6 GO:0002484 antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway(GO:0002484) antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent(GO:0002485)
0.1 1.0 GO:1901750 peptide modification(GO:0031179) leukotriene D4 metabolic process(GO:1901748) leukotriene D4 biosynthetic process(GO:1901750)
0.1 1.2 GO:0009092 homoserine metabolic process(GO:0009092) transsulfuration(GO:0019346) hydrogen sulfide biosynthetic process(GO:0070814)
0.1 0.5 GO:0030043 actin filament fragmentation(GO:0030043)
0.1 0.4 GO:0036388 pre-replicative complex assembly involved in nuclear cell cycle DNA replication(GO:0006267) pre-replicative complex assembly(GO:0036388) DNA replication preinitiation complex assembly(GO:0071163) pre-replicative complex assembly involved in cell cycle DNA replication(GO:1902299)
0.1 3.4 GO:0050872 white fat cell differentiation(GO:0050872)
0.1 0.3 GO:0042374 phylloquinone metabolic process(GO:0042374) phylloquinone catabolic process(GO:0042376) quinone catabolic process(GO:1901662)
0.1 0.2 GO:0010593 negative regulation of lamellipodium assembly(GO:0010593)
0.1 0.3 GO:1903167 enzyme active site formation via L-cysteine sulfinic acid(GO:0018323) primary alcohol biosynthetic process(GO:0034309) cellular response to glyoxal(GO:0036471) neuron intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:0036482) glycolate biosynthetic process(GO:0046295) positive regulation of mitochondrial electron transport, NADH to ubiquinone(GO:1902958) negative regulation of TRAIL-activated apoptotic signaling pathway(GO:1903122) regulation of pyrroline-5-carboxylate reductase activity(GO:1903167) positive regulation of pyrroline-5-carboxylate reductase activity(GO:1903168) regulation of tyrosine 3-monooxygenase activity(GO:1903176) positive regulation of tyrosine 3-monooxygenase activity(GO:1903178) L-dopa metabolic process(GO:1903184) L-dopa biosynthetic process(GO:1903185) glyoxal metabolic process(GO:1903189) regulation of L-dopa biosynthetic process(GO:1903195) positive regulation of L-dopa biosynthetic process(GO:1903197) regulation of L-dopa decarboxylase activity(GO:1903198) positive regulation of L-dopa decarboxylase activity(GO:1903200) regulation of hydrogen peroxide-induced neuron intrinsic apoptotic signaling pathway(GO:1903383) negative regulation of hydrogen peroxide-induced neuron intrinsic apoptotic signaling pathway(GO:1903384) positive regulation of cellular amino acid biosynthetic process(GO:2000284)
0.1 0.2 GO:0002660 positive regulation of tolerance induction dependent upon immune response(GO:0002654) regulation of peripheral tolerance induction(GO:0002658) positive regulation of peripheral tolerance induction(GO:0002660) regulation of peripheral T cell tolerance induction(GO:0002849) positive regulation of peripheral T cell tolerance induction(GO:0002851)
0.1 0.5 GO:1901842 negative regulation of high voltage-gated calcium channel activity(GO:1901842)
0.1 0.5 GO:0071630 nucleus-associated proteasomal ubiquitin-dependent protein catabolic process(GO:0071630)
0.1 0.9 GO:0033689 negative regulation of osteoblast proliferation(GO:0033689)
0.1 0.4 GO:0042276 error-prone translesion synthesis(GO:0042276)
0.1 0.2 GO:0021526 medial motor column neuron differentiation(GO:0021526)
0.1 0.7 GO:1903797 positive regulation of sodium ion export(GO:1903275) positive regulation of sodium ion export from cell(GO:1903278) positive regulation of inorganic anion transmembrane transport(GO:1903797)
0.1 0.4 GO:1901970 positive regulation of mitotic metaphase/anaphase transition(GO:0045842) positive regulation of mitotic sister chromatid separation(GO:1901970) positive regulation of metaphase/anaphase transition of cell cycle(GO:1902101)
0.1 1.1 GO:0070633 transepithelial transport(GO:0070633)
0.1 0.3 GO:0099558 maintenance of synapse structure(GO:0099558)
0.1 0.7 GO:0097421 liver regeneration(GO:0097421)
0.1 0.5 GO:0009249 protein lipoylation(GO:0009249)
0.1 0.2 GO:0002276 basophil activation involved in immune response(GO:0002276)
0.1 0.1 GO:0031938 regulation of chromatin silencing at telomere(GO:0031938)
0.0 0.2 GO:0099566 regulation of postsynaptic cytosolic calcium ion concentration(GO:0099566)
0.0 1.3 GO:0038092 nodal signaling pathway(GO:0038092)
0.0 0.3 GO:0002554 serotonin secretion by platelet(GO:0002554)
0.0 0.3 GO:0097368 establishment of Sertoli cell barrier(GO:0097368)
0.0 0.2 GO:0010637 negative regulation of mitochondrial fusion(GO:0010637)
0.0 0.2 GO:0060460 subthalamic nucleus development(GO:0021763) left lung morphogenesis(GO:0060460) superior vena cava morphogenesis(GO:0060578)
0.0 1.5 GO:0019731 antibacterial humoral response(GO:0019731)
0.0 0.1 GO:0034970 histone H3-R2 methylation(GO:0034970)
0.0 0.2 GO:0044375 regulation of peroxisome size(GO:0044375)
0.0 0.1 GO:0035993 deltoid tuberosity development(GO:0035993)
0.0 0.1 GO:0010286 heat acclimation(GO:0010286)
0.0 0.8 GO:0008535 cellular copper ion homeostasis(GO:0006878) respiratory chain complex IV assembly(GO:0008535)
0.0 0.0 GO:0014057 positive regulation of acetylcholine secretion, neurotransmission(GO:0014057)
0.0 0.1 GO:0045163 clustering of voltage-gated potassium channels(GO:0045163)
0.0 0.1 GO:0071469 cellular response to alkaline pH(GO:0071469)
0.0 0.0 GO:0007352 zygotic specification of dorsal/ventral axis(GO:0007352)
0.0 0.2 GO:0060708 spongiotrophoblast differentiation(GO:0060708)
0.0 0.3 GO:0032926 negative regulation of activin receptor signaling pathway(GO:0032926)
0.0 0.1 GO:0042631 cellular response to water deprivation(GO:0042631)
0.0 0.3 GO:0042637 catagen(GO:0042637)
0.0 0.1 GO:0045054 constitutive secretory pathway(GO:0045054)
0.0 2.2 GO:0006695 cholesterol biosynthetic process(GO:0006695)
0.0 0.2 GO:0051835 positive regulation of synapse structural plasticity(GO:0051835)
0.0 0.8 GO:0018345 protein palmitoylation(GO:0018345)
0.0 0.4 GO:0071294 cellular response to zinc ion(GO:0071294)
0.0 0.1 GO:2000210 positive regulation of anoikis(GO:2000210)
0.0 0.6 GO:0042297 vocal learning(GO:0042297) imitative learning(GO:0098596)
0.0 0.3 GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
0.0 0.7 GO:0045780 positive regulation of bone resorption(GO:0045780) positive regulation of bone remodeling(GO:0046852)
0.0 0.3 GO:0098870 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.0 0.8 GO:0006779 porphyrin-containing compound biosynthetic process(GO:0006779)
0.0 0.1 GO:1904879 positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1904879)
0.0 0.1 GO:0045110 intermediate filament bundle assembly(GO:0045110)
0.0 0.2 GO:0005981 regulation of glycogen catabolic process(GO:0005981)
0.0 0.3 GO:0051798 positive regulation of hair follicle development(GO:0051798)
0.0 0.3 GO:1902018 negative regulation of cilium assembly(GO:1902018)
0.0 0.2 GO:0006398 mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.0 0.1 GO:0010756 positive regulation of plasminogen activation(GO:0010756)
0.0 0.3 GO:0032287 peripheral nervous system myelin maintenance(GO:0032287)
0.0 0.2 GO:0007158 neuron cell-cell adhesion(GO:0007158)
0.0 0.1 GO:0009405 pathogenesis(GO:0009405)
0.0 0.1 GO:0046947 hydroxylysine metabolic process(GO:0046946) hydroxylysine biosynthetic process(GO:0046947)
0.0 0.4 GO:0044381 glucose import in response to insulin stimulus(GO:0044381)
0.0 0.2 GO:0031914 negative regulation of synaptic plasticity(GO:0031914)
0.0 0.7 GO:0010107 potassium ion import(GO:0010107)
0.0 0.1 GO:2000836 positive regulation of androgen secretion(GO:2000836)
0.0 0.5 GO:1905144 acetylcholine receptor signaling pathway(GO:0095500) signal transduction involved in cellular response to ammonium ion(GO:1903831) response to acetylcholine(GO:1905144) cellular response to acetylcholine(GO:1905145)
0.0 0.2 GO:0071318 cellular response to ATP(GO:0071318)
0.0 0.1 GO:0006526 arginine biosynthetic process(GO:0006526)
0.0 0.5 GO:0045662 negative regulation of myoblast differentiation(GO:0045662)
0.0 0.2 GO:0051045 negative regulation of membrane protein ectodomain proteolysis(GO:0051045)
0.0 0.1 GO:0035616 histone H2B conserved C-terminal lysine deubiquitination(GO:0035616)
0.0 0.3 GO:0043011 myeloid dendritic cell differentiation(GO:0043011)
0.0 0.4 GO:0019884 antigen processing and presentation of exogenous antigen(GO:0019884)
0.0 0.4 GO:0015985 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.0 0.3 GO:0035414 negative regulation of catenin import into nucleus(GO:0035414)
0.0 0.2 GO:0048280 vesicle fusion with Golgi apparatus(GO:0048280)
0.0 0.1 GO:0060662 tube lumen cavitation(GO:0060605) salivary gland cavitation(GO:0060662)
0.0 0.1 GO:2001183 negative regulation of interleukin-12 secretion(GO:2001183)
0.0 0.2 GO:0060134 prepulse inhibition(GO:0060134)
0.0 0.2 GO:0035721 intraciliary retrograde transport(GO:0035721)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 2.4 GO:0097129 cyclin D2-CDK4 complex(GO:0097129)
0.2 0.9 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.1 1.6 GO:0031415 NatA complex(GO:0031415)
0.1 0.8 GO:0031095 platelet dense tubular network membrane(GO:0031095)
0.1 0.4 GO:0005656 nuclear pre-replicative complex(GO:0005656) pre-replicative complex(GO:0036387)
0.1 0.5 GO:0000172 ribonuclease MRP complex(GO:0000172)
0.1 0.7 GO:0070552 BRISC complex(GO:0070552)
0.1 0.4 GO:0008622 epsilon DNA polymerase complex(GO:0008622)
0.1 0.3 GO:0030312 external encapsulating structure(GO:0030312)
0.1 0.6 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.1 0.4 GO:0000805 X chromosome(GO:0000805)
0.1 0.3 GO:0044301 climbing fiber(GO:0044301)
0.0 0.2 GO:0031084 BLOC-2 complex(GO:0031084)
0.0 0.6 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.0 0.6 GO:0042612 MHC class I protein complex(GO:0042612)
0.0 0.2 GO:0014802 terminal cisterna(GO:0014802)
0.0 0.9 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.0 0.8 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.0 0.2 GO:0005683 U7 snRNP(GO:0005683)
0.0 0.4 GO:0005750 mitochondrial respiratory chain complex III(GO:0005750)
0.0 1.9 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 0.2 GO:0072357 PTW/PP1 phosphatase complex(GO:0072357)
0.0 0.4 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.0 0.2 GO:0044279 growing cell tip(GO:0035838) other organism cell membrane(GO:0044218) other organism membrane(GO:0044279)
0.0 0.4 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0 0.2 GO:0000808 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.0 0.6 GO:0005839 proteasome core complex(GO:0005839)
0.0 1.0 GO:0030134 ER to Golgi transport vesicle(GO:0030134)
0.0 0.5 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.0 0.4 GO:0032593 insulin-responsive compartment(GO:0032593)
0.0 0.2 GO:1990316 ATG1/ULK1 kinase complex(GO:1990316)
0.0 0.3 GO:0045180 basal cortex(GO:0045180)
0.0 1.2 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 0.0 GO:0034673 inhibin-betaglycan-ActRII complex(GO:0034673) inhibin A complex(GO:0043512)
0.0 0.2 GO:0030991 intraciliary transport particle A(GO:0030991)
0.0 0.8 GO:0030964 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 0.9 GO:0000315 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0 1.9 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.0 0.3 GO:0035253 ciliary rootlet(GO:0035253)
0.0 0.4 GO:0005680 anaphase-promoting complex(GO:0005680)
0.0 0.1 GO:0031933 telomeric heterochromatin(GO:0031933)
0.0 1.8 GO:0017053 transcriptional repressor complex(GO:0017053)
0.0 0.0 GO:0045275 respiratory chain complex III(GO:0045275)
0.0 0.8 GO:0005844 polysome(GO:0005844)
0.0 0.2 GO:0005640 nuclear outer membrane(GO:0005640)
0.0 0.3 GO:0046930 pore complex(GO:0046930)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.2 GO:0016784 3-mercaptopyruvate sulfurtransferase activity(GO:0016784)
0.3 0.8 GO:0004454 ketohexokinase activity(GO:0004454)
0.2 1.6 GO:1990190 peptide-glutamate-N-acetyltransferase activity(GO:1990190)
0.2 0.9 GO:0048030 disaccharide binding(GO:0048030)
0.2 0.9 GO:0031720 haptoglobin binding(GO:0031720) hemoglobin alpha binding(GO:0031721)
0.2 0.5 GO:0004421 hydroxymethylglutaryl-CoA synthase activity(GO:0004421)
0.2 0.5 GO:0000171 ribonuclease MRP activity(GO:0000171)
0.1 0.7 GO:0016971 flavin-linked sulfhydryl oxidase activity(GO:0016971)
0.1 1.1 GO:0046974 histone methyltransferase activity (H3-K9 specific)(GO:0046974)
0.1 2.4 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.1 1.1 GO:0004340 glucokinase activity(GO:0004340) hexokinase activity(GO:0004396)
0.1 0.5 GO:0034041 sterol-transporting ATPase activity(GO:0034041)
0.1 1.7 GO:0008301 DNA binding, bending(GO:0008301)
0.1 0.3 GO:0036470 tyrosine 3-monooxygenase activator activity(GO:0036470) L-dopa decarboxylase activator activity(GO:0036478)
0.1 1.0 GO:0036374 glutathione hydrolase activity(GO:0036374)
0.1 0.4 GO:0055056 D-glucose transmembrane transporter activity(GO:0055056)
0.1 0.6 GO:0031821 G-protein coupled serotonin receptor binding(GO:0031821)
0.1 0.6 GO:0015272 ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.1 0.3 GO:0005459 UDP-galactose transmembrane transporter activity(GO:0005459)
0.1 0.6 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.1 0.4 GO:0030171 voltage-gated proton channel activity(GO:0030171)
0.1 1.1 GO:0070513 death domain binding(GO:0070513)
0.1 1.8 GO:0016628 oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor(GO:0016628)
0.1 0.2 GO:0071209 U7 snRNA binding(GO:0071209)
0.0 0.3 GO:0000253 3-keto sterol reductase activity(GO:0000253)
0.0 0.6 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.0 2.5 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.0 1.9 GO:0017134 fibroblast growth factor binding(GO:0017134)
0.0 0.4 GO:0030550 acetylcholine receptor inhibitor activity(GO:0030550)
0.0 0.2 GO:0005219 ryanodine-sensitive calcium-release channel activity(GO:0005219)
0.0 0.2 GO:0035651 AP-3 adaptor complex binding(GO:0035651)
0.0 0.4 GO:0061133 endopeptidase activator activity(GO:0061133)
0.0 0.6 GO:0030881 beta-2-microglobulin binding(GO:0030881)
0.0 0.1 GO:0046969 histone deacetylase activity (H3-K9 specific)(GO:0032129) NAD-dependent histone deacetylase activity (H3-K9 specific)(GO:0046969)
0.0 0.6 GO:0003688 DNA replication origin binding(GO:0003688)
0.0 0.3 GO:0004931 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.0 0.2 GO:0099583 neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration(GO:0099583)
0.0 0.5 GO:0008656 cysteine-type endopeptidase activator activity involved in apoptotic process(GO:0008656)
0.0 0.1 GO:0097604 temperature-gated cation channel activity(GO:0097604)
0.0 0.1 GO:0004045 aminoacyl-tRNA hydrolase activity(GO:0004045)
0.0 0.7 GO:0070410 co-SMAD binding(GO:0070410)
0.0 0.2 GO:0005519 cytoskeletal regulatory protein binding(GO:0005519)
0.0 0.8 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 0.6 GO:0070003 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0 0.6 GO:0097602 cullin family protein binding(GO:0097602)
0.0 0.4 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.0 0.3 GO:0048185 activin binding(GO:0048185)
0.0 0.1 GO:0044020 protein-arginine omega-N monomethyltransferase activity(GO:0035241) histone methyltransferase activity (H4-R3 specific)(GO:0044020)
0.0 0.2 GO:0051525 NFAT protein binding(GO:0051525)
0.0 0.2 GO:0000293 ferric-chelate reductase activity(GO:0000293)
0.0 0.1 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.0 0.2 GO:0051022 Rho GDP-dissociation inhibitor binding(GO:0051022)
0.0 1.6 GO:0017080 sodium channel regulator activity(GO:0017080)
0.0 0.5 GO:0031402 voltage-gated sodium channel activity(GO:0005248) sodium ion binding(GO:0031402)
0.0 0.1 GO:0034618 arginine binding(GO:0034618)
0.0 0.5 GO:0015114 phosphate ion transmembrane transporter activity(GO:0015114)
0.0 0.2 GO:0004972 NMDA glutamate receptor activity(GO:0004972)
0.0 0.4 GO:0016676 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 0.5 GO:0008266 poly(U) RNA binding(GO:0008266)
0.0 4.4 GO:0030414 peptidase inhibitor activity(GO:0030414)
0.0 0.1 GO:0008475 procollagen-lysine 5-dioxygenase activity(GO:0008475)
0.0 0.1 GO:0001594 trace-amine receptor activity(GO:0001594)
0.0 0.7 GO:0003785 actin monomer binding(GO:0003785)
0.0 1.8 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979)
0.0 0.0 GO:0070506 high-density lipoprotein particle receptor activity(GO:0070506)
0.0 1.0 GO:0001540 beta-amyloid binding(GO:0001540)
0.0 0.3 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.0 0.1 GO:0071535 RING-like zinc finger domain binding(GO:0071535)
0.0 0.1 GO:0008242 omega peptidase activity(GO:0008242)
0.0 0.2 GO:0008097 5S rRNA binding(GO:0008097)
0.0 0.1 GO:0030160 GKAP/Homer scaffold activity(GO:0030160)
0.0 0.2 GO:0019869 chloride channel inhibitor activity(GO:0019869)
0.0 0.4 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.0 0.1 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
0.0 0.0 GO:0016314 phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity(GO:0016314)
0.0 1.1 GO:0004843 thiol-dependent ubiquitin-specific protease activity(GO:0004843)
0.0 0.5 GO:0004407 histone deacetylase activity(GO:0004407)
0.0 0.3 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.7 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0 3.1 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 0.6 PID S1P S1P4 PATHWAY S1P4 pathway
0.0 0.1 PID LPA4 PATHWAY LPA4-mediated signaling events
0.0 0.2 PID REELIN PATHWAY Reelin signaling pathway
0.0 2.2 PID ILK PATHWAY Integrin-linked kinase signaling
0.0 3.3 PID CMYB PATHWAY C-MYB transcription factor network
0.0 0.9 PID TRAIL PATHWAY TRAIL signaling pathway
0.0 1.0 PID RAS PATHWAY Regulation of Ras family activation
0.0 0.4 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0 0.3 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.3 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 0.8 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.0 1.3 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.0 1.1 REACTOME RNA POL I TRANSCRIPTION INITIATION Genes involved in RNA Polymerase I Transcription Initiation
0.0 1.3 REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.0 2.1 REACTOME G1 PHASE Genes involved in G1 Phase
0.0 0.7 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.0 0.9 REACTOME SEMA3A PAK DEPENDENT AXON REPULSION Genes involved in Sema3A PAK dependent Axon repulsion
0.0 1.9 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0 0.9 REACTOME KINESINS Genes involved in Kinesins
0.0 0.3 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.0 0.4 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.0 1.3 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 0.2 REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX Genes involved in CDC6 association with the ORC:origin complex
0.0 0.4 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.0 0.4 REACTOME APC C CDC20 MEDIATED DEGRADATION OF CYCLIN B Genes involved in APC/C:Cdc20 mediated degradation of Cyclin B
0.0 0.4 REACTOME REPAIR SYNTHESIS FOR GAP FILLING BY DNA POL IN TC NER Genes involved in Repair synthesis for gap-filling by DNA polymerase in TC-NER
0.0 1.0 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.0 1.0 REACTOME AUTODEGRADATION OF CDH1 BY CDH1 APC C Genes involved in Autodegradation of Cdh1 by Cdh1:APC/C
0.0 0.4 REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.0 0.7 REACTOME INWARDLY RECTIFYING K CHANNELS Genes involved in Inwardly rectifying K+ channels
0.0 0.2 REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.0 0.1 REACTOME OLFACTORY SIGNALING PATHWAY Genes involved in Olfactory Signaling Pathway
0.0 1.9 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.0 0.6 REACTOME GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.0 0.7 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.0 0.6 REACTOME G PROTEIN ACTIVATION Genes involved in G-protein activation
0.0 0.2 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 0.8 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport