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GSE58827: Dynamics of the Mouse Liver

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Results for Lhx4

Z-value: 0.51

Motif logo

Transcription factors associated with Lhx4

Gene Symbol Gene ID Gene Info
ENSMUSG00000026468.15 LIM homeobox protein 4

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Lhx4mm39_v1_chr1_-_155617773_155617790-0.057.5e-01Click!

Activity profile of Lhx4 motif

Sorted Z-values of Lhx4 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr14_+_80237691 5.98 ENSMUST00000228749.2
ENSMUST00000088735.4
olfactomedin 4
chr11_+_32236945 4.13 ENSMUST00000101387.4
hemoglobin, theta 1B
chr4_+_114914880 2.83 ENSMUST00000161601.8
T cell acute lymphocytic leukemia 1
chr15_+_82225380 2.67 ENSMUST00000050349.3
PH domain containing endocytic trafficking adaptor 2
chrX_+_149330371 2.39 ENSMUST00000066337.13
ENSMUST00000112715.2
aminolevulinic acid synthase 2, erythroid
chr10_+_75402090 2.00 ENSMUST00000129232.8
ENSMUST00000143792.8
gamma-glutamyltransferase 1
chr6_-_136918885 1.93 ENSMUST00000111891.4
Rho, GDP dissociation inhibitor (GDI) beta
chrX_-_73290140 1.59 ENSMUST00000101454.9
ENSMUST00000033699.13
filamin, alpha
chr6_-_41423004 1.59 ENSMUST00000095999.7
predicted gene 10334
chr6_-_115014777 1.58 ENSMUST00000174848.8
ENSMUST00000032461.12
TAM41 mitochondrial translocator assembly and maintenance homolog
chr9_+_96140781 1.55 ENSMUST00000190104.7
ENSMUST00000179416.8
ENSMUST00000189606.7
transcription factor Dp 2
chr14_+_26722319 1.54 ENSMUST00000035433.10
homeobox gene expressed in ES cells
chrX_-_138772383 1.53 ENSMUST00000033811.14
ENSMUST00000087401.12
microrchidia 4
chr19_-_46033353 1.49 ENSMUST00000026252.14
ENSMUST00000156585.9
ENSMUST00000185355.7
ENSMUST00000152946.8
LIM domain binding 1
chr6_-_41354538 1.43 ENSMUST00000096003.7
protease, serine 3
chrX_-_73289970 1.42 ENSMUST00000130007.8
filamin, alpha
chr9_+_118892497 1.33 ENSMUST00000141185.8
ENSMUST00000126251.8
ENSMUST00000136561.2
villin-like
chr2_+_163500290 1.26 ENSMUST00000164399.8
ENSMUST00000064703.13
ENSMUST00000099105.9
ENSMUST00000152418.8
ENSMUST00000126182.8
ENSMUST00000131228.8
protein kinase inhibitor, gamma
chr17_+_34811217 1.23 ENSMUST00000038149.13
pre B cell leukemia homeobox 2
chr16_-_21980200 1.19 ENSMUST00000115379.2
insulin-like growth factor 2 mRNA binding protein 2
chr10_+_79832313 1.15 ENSMUST00000132517.8
ATP-binding cassette, sub-family A (ABC1), member 7
chr3_-_14843512 1.06 ENSMUST00000094365.11
carbonic anhydrase 1
chr7_+_30193047 0.99 ENSMUST00000058280.13
ENSMUST00000133318.8
ENSMUST00000142575.8
ENSMUST00000131040.2
proline dehydrogenase (oxidase) 2
chr5_+_35156389 0.94 ENSMUST00000114281.8
ENSMUST00000114280.8
regulator of G-protein signaling 12
chr17_+_46961250 0.94 ENSMUST00000043464.14
cullin 7
chr3_-_86827640 0.93 ENSMUST00000195561.6
doublecortin-like kinase 2
chr9_+_64188857 0.92 ENSMUST00000215031.2
ENSMUST00000213165.2
ENSMUST00000213289.2
ENSMUST00000216594.2
ENSMUST00000034964.7
timeless interacting protein
chr5_-_122959321 0.89 ENSMUST00000197074.5
ENSMUST00000199406.5
ENSMUST00000196640.5
ENSMUST00000197719.5
ENSMUST00000200645.5
anaphase-promoting complex subunit 5
chr3_-_86827664 0.87 ENSMUST00000194452.2
ENSMUST00000191752.6
doublecortin-like kinase 2
chr7_-_45480200 0.86 ENSMUST00000107723.9
ENSMUST00000131384.3
glutamate-rich WD repeat containing 1
chr1_+_34511793 0.84 ENSMUST00000188972.3
protein tyrosine phosphatase, non-receptor type 18
chr19_+_5524701 0.84 ENSMUST00000165485.8
ENSMUST00000166253.8
ENSMUST00000167371.8
ENSMUST00000167855.8
ENSMUST00000070118.14
epidermal growth factor-containing fibulin-like extracellular matrix protein 2
chr4_+_34893772 0.83 ENSMUST00000029975.10
ENSMUST00000135871.8
ENSMUST00000108130.2
glycoprotein hormones, alpha subunit
chr3_+_89622323 0.82 ENSMUST00000098924.9
adenosine deaminase, RNA-specific
chr9_+_96140750 0.81 ENSMUST00000186609.7
transcription factor Dp 2
chr10_-_35587888 0.80 ENSMUST00000080898.4
S-adenosylmethionine decarboxylase 2
chrX_-_101200670 0.80 ENSMUST00000056904.3
excision repair cross-complementing rodent repair deficiency complementation group 6 like
chr13_+_20274708 0.80 ENSMUST00000072519.7
engulfment and cell motility 1
chr2_+_36120438 0.78 ENSMUST00000062069.6
prostaglandin-endoperoxide synthase 1
chr6_+_123239076 0.75 ENSMUST00000032240.4
C-type lectin domain family 4, member d
chr15_-_103123711 0.73 ENSMUST00000122182.2
ENSMUST00000108813.10
ENSMUST00000127191.2
chromobox 5
chr7_-_108774367 0.72 ENSMUST00000207178.2
LIM domain only 1
chr1_+_63216281 0.69 ENSMUST00000188524.2
eukaryotic translation elongation factor 1 beta 2
chr6_+_72074718 0.68 ENSMUST00000187007.3
ST3 beta-galactoside alpha-2,3-sialyltransferase 5
chr17_-_56343531 0.68 ENSMUST00000233803.2
SH3-domain GRB2-like 1
chr17_-_56343625 0.68 ENSMUST00000003268.11
SH3-domain GRB2-like 1
chr6_+_72074545 0.66 ENSMUST00000069994.11
ENSMUST00000114112.4
ST3 beta-galactoside alpha-2,3-sialyltransferase 5
chr9_+_21437440 0.65 ENSMUST00000086361.12
ENSMUST00000173769.3
cDNA sequence AB124611
chr3_-_88317601 0.64 ENSMUST00000193338.6
ENSMUST00000056370.13
polyamine-modulated factor 1
chr5_+_35156454 0.63 ENSMUST00000114283.8
regulator of G-protein signaling 12
chr1_-_36312482 0.62 ENSMUST00000056946.8
neuralized E3 ubiquitin protein ligase 3
chr1_+_63215976 0.61 ENSMUST00000129339.8
eukaryotic translation elongation factor 1 beta 2
chr17_-_24292453 0.61 ENSMUST00000017090.6
potassium channel tetramerisation domain containing 5
chrX_+_152506577 0.61 ENSMUST00000140575.8
ENSMUST00000208373.2
ENSMUST00000185492.7
ENSMUST00000149514.8
negative regulator of P-body association
chr15_-_98507913 0.60 ENSMUST00000226500.2
ENSMUST00000227501.2
adenylate cyclase 6
chr19_-_39875192 0.57 ENSMUST00000168838.3
cytochrome P450, family 2, subfamily c, polypeptide 69
chr6_-_30936013 0.56 ENSMUST00000101589.5
Kruppel-like factor 14
chr1_+_85503397 0.54 ENSMUST00000178024.2
RIKEN cDNA G530012D1 gene
chr7_-_5017642 0.54 ENSMUST00000207412.2
ENSMUST00000077385.15
ENSMUST00000165320.3
Flt3 interacting zinc finger protein 1
chr10_-_37014859 0.50 ENSMUST00000092584.6
myristoylated alanine rich protein kinase C substrate
chr7_-_115459082 0.50 ENSMUST00000206123.2
SRY (sex determining region Y)-box 6
chr19_+_46385321 0.50 ENSMUST00000039922.13
ENSMUST00000111867.9
ENSMUST00000120778.8
SUFU negative regulator of hedgehog signaling
chr3_-_72875187 0.49 ENSMUST00000167334.8
sucrase isomaltase (alpha-glucosidase)
chr7_-_37472979 0.47 ENSMUST00000176534.8
zinc finger protein 536
chr10_-_75946790 0.47 ENSMUST00000120757.2
solute carrier family 5 (neutral amino acid transporters, system A), member 4b
chr3_+_68776884 0.47 ENSMUST00000054551.3
RIKEN cDNA 1110032F04 gene
chr18_+_52958382 0.46 ENSMUST00000238707.2
predicted gene, 50457
chr2_-_174188505 0.46 ENSMUST00000168292.2
predicted gene, 20721
chr7_+_45271229 0.45 ENSMUST00000033100.5
izumo sperm-egg fusion 1
chrX_+_132751729 0.44 ENSMUST00000033602.9
tenomodulin
chr14_+_57762191 0.44 ENSMUST00000089494.6
interleukin 17D
chr2_-_88157559 0.43 ENSMUST00000214207.2
olfactory receptor 1175
chrX_+_9751861 0.42 ENSMUST00000067529.9
ENSMUST00000086165.4
synaptotagmin-like 5
chr6_+_136509922 0.42 ENSMUST00000187429.4
activating transcription factor 7 interacting protein
chr2_+_109522781 0.40 ENSMUST00000111050.10
brain derived neurotrophic factor
chr7_-_15781838 0.37 ENSMUST00000210781.2
BRD4 interacting chromatin remodeling complex associated protein
chrX_-_8118541 0.37 ENSMUST00000115594.8
ENSMUST00000115595.8
ENSMUST00000033513.10
FtsJ RNA methyltransferase homolog 1 (E. coli)
chr11_+_6510167 0.37 ENSMUST00000109722.9
cerebral cavernous malformation 2
chr2_+_85838122 0.33 ENSMUST00000062166.2
olfactory receptor 1032
chr7_+_89814713 0.33 ENSMUST00000207084.2
phosphatidylinositol binding clathrin assembly protein
chrX_+_168468186 0.33 ENSMUST00000112107.8
ENSMUST00000112104.8
midline 1
chr2_+_87696836 0.33 ENSMUST00000213308.3
olfactory receptor 1152
chr2_-_34716199 0.32 ENSMUST00000113075.8
ENSMUST00000113080.9
ENSMUST00000091020.10
F-box and WD-40 domain protein 2
chr16_-_90607251 0.32 ENSMUST00000140920.2
URB1 ribosome biogenesis 1 homolog (S. cerevisiae)
chr2_-_111843053 0.31 ENSMUST00000213559.3
olfactory receptor 1310
chr9_-_49710190 0.31 ENSMUST00000114476.8
ENSMUST00000193547.6
neural cell adhesion molecule 1
chr6_-_141719536 0.30 ENSMUST00000148411.2
predicted gene 5724
chr10_-_23112973 0.30 ENSMUST00000218049.2
EYA transcriptional coactivator and phosphatase 4
chr9_-_49710058 0.30 ENSMUST00000192584.2
ENSMUST00000166811.9
neural cell adhesion molecule 1
chr10_+_102376109 0.30 ENSMUST00000055355.6
Ras association (RalGDS/AF-6) domain family (N-terminal) member 9
chr15_+_34453432 0.29 ENSMUST00000060894.9
glutamate rich 5
chr10_+_101994841 0.29 ENSMUST00000020039.13
MGAT4 family, member C
chr8_+_66964401 0.29 ENSMUST00000002025.5
ENSMUST00000183187.2
transketolase-like 2
chr5_-_53864595 0.29 ENSMUST00000200691.4
cholecystokinin A receptor
chr7_+_126575510 0.29 ENSMUST00000206780.2
CDP-diacylglycerol--inositol 3-phosphatidyltransferase (phosphatidylinositol synthase)
chr12_-_118930130 0.28 ENSMUST00000035515.5
ATP-binding cassette, sub-family B (MDR/TAP), member 5
chr4_+_146586445 0.28 ENSMUST00000105735.9
zinc finger protein 981
chr4_+_134658209 0.28 ENSMUST00000030622.3
SYF2 homolog, RNA splicing factor (S. cerevisiae)
chr10_+_74872898 0.28 ENSMUST00000147802.9
ENSMUST00000020391.13
ENSMUST00000234625.2
RAB36, member RAS oncogene family
chr5_+_107656810 0.28 ENSMUST00000160160.6
predicted gene 42669
chr4_+_148985584 0.27 ENSMUST00000147270.2
castor zinc finger 1
chr2_+_86122799 0.27 ENSMUST00000217166.2
olfactory receptor 1052
chr12_+_38833501 0.27 ENSMUST00000159334.8
ets variant 1
chr14_+_8283087 0.27 ENSMUST00000206298.3
ENSMUST00000216079.2
olfactory receptor 720
chr4_+_145311759 0.27 ENSMUST00000119718.8
zinc finger protein 268
chr12_+_59060162 0.27 ENSMUST00000021379.8
gem nuclear organelle associated protein 2
chr12_+_38833454 0.26 ENSMUST00000161980.8
ENSMUST00000160701.8
ets variant 1
chr11_+_76795292 0.26 ENSMUST00000142166.8
transmembrane and immunoglobulin domain containing 1
chr16_+_58967409 0.26 ENSMUST00000216957.3
olfactory receptor 195
chr5_-_86893645 0.26 ENSMUST00000161306.2
transmembrane protease, serine 11e
chr2_-_86944911 0.26 ENSMUST00000216088.3
olfactory receptor 259
chr12_-_111947487 0.26 ENSMUST00000190536.2
retinal degeneration 3-like
chr14_-_110992533 0.26 ENSMUST00000078386.4
SLIT and NTRK-like family, member 6
chr8_+_13919641 0.25 ENSMUST00000051870.8
ENSMUST00000128557.3
chromosome alignment maintaining phosphoprotein 1
chr10_-_40178182 0.25 ENSMUST00000099945.6
ENSMUST00000238953.2
ENSMUST00000238969.2
S-adenosylmethionine decarboxylase 1
chr2_-_34716083 0.24 ENSMUST00000113077.8
ENSMUST00000028220.10
F-box and WD-40 domain protein 2
chr12_-_111947536 0.24 ENSMUST00000185354.2
retinal degeneration 3-like
chr7_+_99808452 0.24 ENSMUST00000032967.4
lipoyl(octanoyl) transferase 2 (putative)
chr8_-_79539838 0.24 ENSMUST00000146824.2
LSM6 homolog, U6 small nuclear RNA and mRNA degradation associated
chr8_-_62576140 0.24 ENSMUST00000034052.14
ENSMUST00000034054.9
annexin A10
chr2_-_111965322 0.24 ENSMUST00000213696.2
olfactory receptor 1316
chr3_+_138058139 0.24 ENSMUST00000090166.5
alcohol dehydrogenase 6B (class V)
chr2_-_89779008 0.23 ENSMUST00000214846.2
olfactory receptor 1259
chr19_-_24178000 0.23 ENSMUST00000233658.3
tight junction protein 2
chr11_+_76795346 0.23 ENSMUST00000072633.4
transmembrane and immunoglobulin domain containing 1
chrX_+_56257374 0.23 ENSMUST00000033466.2
CD40 ligand
chr11_+_31823096 0.23 ENSMUST00000155278.2
cytoplasmic polyadenylation element binding protein 4
chr6_-_69282389 0.22 ENSMUST00000103350.3
immunoglobulin kappa variable 4-68
chr2_-_73284262 0.22 ENSMUST00000102679.8
WAS/WASL interacting protein family, member 1
chr2_-_87570322 0.22 ENSMUST00000214573.2
olfactory receptor 1138
chr14_-_50479161 0.22 ENSMUST00000214388.2
olfactory receptor 731
chr4_-_45532470 0.21 ENSMUST00000147448.2
src homology 2 domain-containing transforming protein B
chr4_-_58499398 0.20 ENSMUST00000107570.2
lysophosphatidic acid receptor 1
chr4_+_147216495 0.20 ENSMUST00000084149.10
zinc finger protein 991
chr16_-_26786995 0.20 ENSMUST00000231969.2
geminin coiled-coil domain containing
chr2_-_86257093 0.20 ENSMUST00000217481.2
olfactory receptor 1062
chr19_-_55229668 0.20 ENSMUST00000069183.8
guanylate cyclase 2g
chr13_-_52685305 0.20 ENSMUST00000057442.8
DIRAS family, GTP-binding RAS-like 2
chr7_+_99808526 0.20 ENSMUST00000207825.2
lipoyl(octanoyl) transferase 2 (putative)
chr17_+_29493113 0.20 ENSMUST00000234326.2
ENSMUST00000235117.2
cDNA sequence BC004004
chr10_-_130230201 0.20 ENSMUST00000094502.6
ENSMUST00000233146.2
vomeronasal 2, receptor 84
chr6_-_136899167 0.20 ENSMUST00000032343.7
endoplasmic reticulum protein 27
chr2_+_85648823 0.20 ENSMUST00000214416.2
olfactory receptor 1018
chr4_+_11558905 0.19 ENSMUST00000095145.12
ENSMUST00000108306.9
ENSMUST00000070755.13
RAD54 homolog B (S. cerevisiae)
chr9_-_103569984 0.19 ENSMUST00000049452.15
transmembrane protein 108
chr14_+_47710574 0.19 ENSMUST00000228740.2
F-box protein 34
chr17_+_17622934 0.19 ENSMUST00000115576.3
limb and CNS expressed 1
chr14_+_8282925 0.19 ENSMUST00000217642.2
olfactory receptor 720
chr2_-_79287095 0.19 ENSMUST00000041099.5
neurogenic differentiation 1
chr14_-_104760051 0.18 ENSMUST00000022716.4
ENSMUST00000228448.2
ENSMUST00000227640.2
ORC ubiquitin ligase 1
chr11_-_73348284 0.18 ENSMUST00000121209.3
ENSMUST00000127789.3
olfactory receptor 380
chr9_+_108216233 0.17 ENSMUST00000082429.8
glutathione peroxidase 1
chr8_-_126296495 0.17 ENSMUST00000212168.2
ENSMUST00000212987.2
signal-induced proliferation-associated 1 like 2
chr10_+_101994719 0.17 ENSMUST00000138522.8
ENSMUST00000163753.8
ENSMUST00000138016.8
MGAT4 family, member C
chr17_+_29493049 0.17 ENSMUST00000149405.4
cDNA sequence BC004004
chr2_-_88562710 0.17 ENSMUST00000213118.2
olfactory receptor 1197
chr19_-_12313274 0.17 ENSMUST00000208398.3
olfactory receptor 1438, pseudogene 1
chr11_-_99433984 0.17 ENSMUST00000107443.8
ENSMUST00000074253.4
keratin 40
chr11_+_62737887 0.17 ENSMUST00000036085.11
F-box and WD-40 domain protein 10
chr4_-_147894245 0.17 ENSMUST00000105734.10
ENSMUST00000176201.2
zinc finger protein 984
predicted gene 20707
chr3_-_96359622 0.17 ENSMUST00000093126.11
ENSMUST00000098841.4
cDNA sequence BC107364
chr11_+_58062467 0.17 ENSMUST00000020820.2
mitochondrial ribosomal protein L22
chr1_-_4430481 0.16 ENSMUST00000027032.6
retinitis pigmentosa 1 (human)
chr14_+_53994813 0.16 ENSMUST00000180380.3
T cell receptor alpha variable 13-4-DV7
chr4_+_145397238 0.16 ENSMUST00000105738.9
zinc finger protein 980
chr6_+_29859685 0.15 ENSMUST00000134438.2
S-adenosylhomocysteine hydrolase-like 2
chr7_+_84562283 0.15 ENSMUST00000216367.2
ENSMUST00000214501.3
olfactory receptor 290
chr19_-_13828056 0.15 ENSMUST00000208493.3
olfactory receptor 1501
chr14_+_27598021 0.15 ENSMUST00000211684.2
ENSMUST00000210924.2
ELKS/RAB6-interacting/CAST family member 2
chr15_+_16778187 0.15 ENSMUST00000026432.8
cadherin 9
chr11_+_62737936 0.15 ENSMUST00000150989.8
ENSMUST00000176577.2
F-box and WD-40 domain protein 10
chr6_+_29859660 0.15 ENSMUST00000128927.9
S-adenosylhomocysteine hydrolase-like 2
chr19_-_45224251 0.15 ENSMUST00000099401.6
ladybird homeobox 1
chrX_-_74621828 0.15 ENSMUST00000033545.6
RAB39B, member RAS oncogene family
chr5_+_13448833 0.15 ENSMUST00000137798.10
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
chr1_-_165462020 0.14 ENSMUST00000194437.6
ENSMUST00000068705.13
ENSMUST00000111435.9
ENSMUST00000193023.2
myelin protein zero-like 1
chr2_+_85545763 0.14 ENSMUST00000216443.3
olfactory receptor 1009
chr7_+_107679062 0.14 ENSMUST00000213601.2
olfactory receptor 481
chr17_+_29493157 0.14 ENSMUST00000234234.2
cDNA sequence BC004004
chr18_+_57601541 0.14 ENSMUST00000091892.4
ENSMUST00000209782.2
cortexin 3
chr15_-_56557920 0.14 ENSMUST00000050544.8
hyaluronan synthase 2
chr6_-_145811028 0.14 ENSMUST00000111703.2
basic helix-loop-helix family, member e41
chr2_+_111084861 0.14 ENSMUST00000218065.2
olfactory receptor 1276
chr9_-_19275301 0.14 ENSMUST00000214810.2
olfactory receptor 846
chr16_-_92196954 0.14 ENSMUST00000023672.10
regulator of calcineurin 1
chr4_+_146695418 0.13 ENSMUST00000130825.8
zinc finger protein 993
chr17_+_70829050 0.13 ENSMUST00000133717.9
ENSMUST00000148486.8
DLG associated protein 1
chr10_+_87041814 0.13 ENSMUST00000189775.2
RIKEN cDNA 1700113H08 gene
chr2_-_87504008 0.13 ENSMUST00000213835.2
olfactory receptor 1135
chr8_+_121854566 0.13 ENSMUST00000181609.2
forkhead box L1
chr19_-_13827773 0.13 ENSMUST00000215350.2
olfactory receptor 1501
chr10_+_115979787 0.12 ENSMUST00000105271.9
protein tyrosine phosphatase, receptor type, R
chr10_+_129601351 0.12 ENSMUST00000203236.3
olfactory receptor 808
chr2_-_7400690 0.12 ENSMUST00000182404.8
CUGBP, Elav-like family member 2
chr6_+_96092230 0.12 ENSMUST00000075080.6
TAFA chemokine like family member 1
chr4_+_147637714 0.12 ENSMUST00000139784.8
ENSMUST00000143885.8
ENSMUST00000081742.7
zinc finger protein 985
chr5_+_13448647 0.12 ENSMUST00000125629.8
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
chr17_-_14914484 0.12 ENSMUST00000170872.3
thrombospondin 2
chr4_+_147390131 0.12 ENSMUST00000148762.4
zinc finger protein 988
chr4_+_145311722 0.12 ENSMUST00000105739.8
zinc finger protein 268

Network of associatons between targets according to the STRING database.

First level regulatory network of Lhx4

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 3.0 GO:1905000 regulation of membrane repolarization during atrial cardiac muscle cell action potential(GO:1905000)
0.9 2.8 GO:0060217 hemangioblast cell differentiation(GO:0060217)
0.5 1.5 GO:0043973 histone H3-K4 acetylation(GO:0043973)
0.4 1.2 GO:1901074 regulation of engulfment of apoptotic cell(GO:1901074)
0.4 1.1 GO:0006597 spermine biosynthetic process(GO:0006597)
0.3 1.0 GO:0010133 proline catabolic process to glutamate(GO:0010133)
0.3 1.6 GO:0038032 termination of G-protein coupled receptor signaling pathway(GO:0038032)
0.3 0.8 GO:1900369 negative regulation of RNA interference(GO:1900369)
0.2 2.0 GO:1901750 peptide modification(GO:0031179) leukotriene D4 metabolic process(GO:1901748) leukotriene D4 biosynthetic process(GO:1901750)
0.2 1.9 GO:1901164 negative regulation of trophoblast cell migration(GO:1901164)
0.2 0.6 GO:1904116 response to vasopressin(GO:1904116) cellular response to vasopressin(GO:1904117)
0.2 0.9 GO:0048478 replication fork protection(GO:0048478)
0.2 2.4 GO:0042541 hemoglobin biosynthetic process(GO:0042541)
0.2 0.6 GO:0001928 regulation of exocyst assembly(GO:0001928)
0.1 0.4 GO:0009107 lipoate biosynthetic process(GO:0009107)
0.1 1.5 GO:0030916 otic vesicle formation(GO:0030916)
0.1 0.4 GO:0061193 taste bud development(GO:0061193)
0.1 1.4 GO:0016191 synaptic vesicle uncoating(GO:0016191)
0.1 0.8 GO:0019371 cyclooxygenase pathway(GO:0019371) maintenance of blood-brain barrier(GO:0035633)
0.1 0.7 GO:0046013 regulation of T cell homeostatic proliferation(GO:0046013)
0.1 1.1 GO:0032049 cardiolipin biosynthetic process(GO:0032049)
0.1 0.7 GO:0038094 Fc-gamma receptor signaling pathway(GO:0038094)
0.1 0.3 GO:0060220 camera-type eye photoreceptor cell fate commitment(GO:0060220)
0.1 6.1 GO:1900026 positive regulation of substrate adhesion-dependent cell spreading(GO:1900026)
0.1 0.3 GO:1903045 neural crest cell migration involved in sympathetic nervous system development(GO:1903045)
0.1 0.6 GO:0021776 smoothened signaling pathway involved in ventral spinal cord interneuron specification(GO:0021775) smoothened signaling pathway involved in spinal cord motor neuron cell fate specification(GO:0021776)
0.1 0.4 GO:0046341 CDP-diacylglycerol metabolic process(GO:0046341)
0.1 2.0 GO:0021860 pyramidal neuron development(GO:0021860)
0.1 0.2 GO:2001200 positive regulation of dendritic cell differentiation(GO:2001200)
0.1 0.8 GO:0046884 follicle-stimulating hormone secretion(GO:0046884)
0.1 0.3 GO:0009609 response to symbiont(GO:0009608) response to symbiotic bacterium(GO:0009609) response to selenium ion(GO:0010269)
0.1 0.2 GO:0060729 intestinal epithelial structure maintenance(GO:0060729)
0.1 0.6 GO:0090520 sphingolipid mediated signaling pathway(GO:0090520)
0.1 1.3 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.1 0.3 GO:1902963 regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902962) negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902963)
0.1 0.2 GO:0050925 negative regulation of negative chemotaxis(GO:0050925)
0.1 0.2 GO:1904565 response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904565) cellular response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904566)
0.1 0.5 GO:2000741 positive regulation of mesenchymal stem cell differentiation(GO:2000741)
0.0 0.3 GO:0090274 reduction of food intake in response to dietary excess(GO:0002023) positive regulation of somatostatin secretion(GO:0090274)
0.0 0.9 GO:0006337 nucleosome disassembly(GO:0006337)
0.0 0.6 GO:0035372 protein localization to microtubule(GO:0035372)
0.0 0.5 GO:1904659 glucose transmembrane transport(GO:1904659)
0.0 0.2 GO:2001205 negative regulation of osteoclast development(GO:2001205)
0.0 0.1 GO:0061146 Peyer's patch morphogenesis(GO:0061146)
0.0 0.1 GO:0038060 nitric oxide-cGMP-mediated signaling pathway(GO:0038060)
0.0 0.2 GO:0060005 vestibular reflex(GO:0060005)
0.0 0.4 GO:0016576 histone dephosphorylation(GO:0016576)
0.0 0.5 GO:0007342 fusion of sperm to egg plasma membrane(GO:0007342)
0.0 0.1 GO:0038128 ERBB2 signaling pathway(GO:0038128)
0.0 0.4 GO:0060837 blood vessel endothelial cell differentiation(GO:0060837)
0.0 0.2 GO:1990416 cellular response to brain-derived neurotrophic factor stimulus(GO:1990416)
0.0 1.1 GO:0009954 proximal/distal pattern formation(GO:0009954)
0.0 0.4 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.0 0.1 GO:0045358 negative regulation of interferon-beta biosynthetic process(GO:0045358)
0.0 1.2 GO:0006730 one-carbon metabolic process(GO:0006730)
0.0 1.3 GO:0018279 protein N-linked glycosylation via asparagine(GO:0018279)
0.0 0.1 GO:0001830 trophectodermal cell fate commitment(GO:0001830)
0.0 1.3 GO:0006414 translational elongation(GO:0006414)
0.0 0.9 GO:0070979 protein K11-linked ubiquitination(GO:0070979)
0.0 0.1 GO:0006421 asparaginyl-tRNA aminoacylation(GO:0006421)
0.0 0.2 GO:2000766 negative regulation of cytoplasmic translation(GO:2000766)
0.0 0.5 GO:0051764 actin crosslink formation(GO:0051764)
0.0 1.3 GO:0051693 actin filament capping(GO:0051693)
0.0 0.2 GO:1900194 negative regulation of oocyte maturation(GO:1900194)
0.0 2.8 GO:0007586 digestion(GO:0007586)
0.0 0.2 GO:0048664 neuron fate determination(GO:0048664)
0.0 0.2 GO:0097118 neuroligin clustering involved in postsynaptic membrane assembly(GO:0097118)
0.0 0.3 GO:0048934 peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.0 0.4 GO:0001886 endothelial cell morphogenesis(GO:0001886)
0.0 0.8 GO:0016601 Rac protein signal transduction(GO:0016601)
0.0 0.1 GO:0032489 regulation of Cdc42 protein signal transduction(GO:0032489)
0.0 0.1 GO:0002302 CD8-positive, alpha-beta T cell differentiation involved in immune response(GO:0002302)
0.0 0.9 GO:0000281 mitotic cytokinesis(GO:0000281)
0.0 0.1 GO:0001661 conditioned taste aversion(GO:0001661) amygdala development(GO:0021764)
0.0 0.4 GO:0045898 regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045898)
0.0 0.2 GO:0035845 photoreceptor cell outer segment organization(GO:0035845)
0.0 0.1 GO:0070889 platelet alpha granule organization(GO:0070889)
0.0 0.0 GO:2000729 positive regulation of mesenchymal cell proliferation involved in ureter development(GO:2000729)
0.0 0.0 GO:0051385 response to mineralocorticoid(GO:0051385)
0.0 0.0 GO:2001226 negative regulation of chloride transport(GO:2001226)
0.0 0.1 GO:0070842 aggresome assembly(GO:0070842)
0.0 0.1 GO:0010944 negative regulation of transcription by competitive promoter binding(GO:0010944)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 2.8 GO:0033193 Lsd1/2 complex(GO:0033193)
0.5 3.0 GO:0031523 Myb complex(GO:0031523)
0.2 6.0 GO:0042581 specific granule(GO:0042581)
0.2 1.3 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.2 0.9 GO:1990393 3M complex(GO:1990393)
0.1 0.8 GO:0044530 supraspliceosomal complex(GO:0044530)
0.1 0.9 GO:0031298 replication fork protection complex(GO:0031298)
0.1 0.6 GO:0000444 MIS12/MIND type complex(GO:0000444)
0.1 0.5 GO:0042585 germinal vesicle(GO:0042585)
0.0 0.3 GO:0070381 endosome to plasma membrane transport vesicle(GO:0070381)
0.0 0.8 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.0 0.3 GO:0097413 Lewy body(GO:0097413)
0.0 1.2 GO:0001891 phagocytic cup(GO:0001891)
0.0 0.3 GO:0097504 Gemini of coiled bodies(GO:0097504)
0.0 1.6 GO:0097440 apical dendrite(GO:0097440)
0.0 0.1 GO:0071007 U2-type catalytic step 2 spliceosome(GO:0071007)
0.0 0.9 GO:0005680 anaphase-promoting complex(GO:0005680)
0.0 0.7 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.0 0.3 GO:0071014 post-mRNA release spliceosomal complex(GO:0071014)
0.0 0.7 GO:0010369 chromocenter(GO:0010369)
0.0 0.1 GO:1904511 cortical microtubule plus-end(GO:1903754) cytoplasmic microtubule plus-end(GO:1904511)
0.0 0.1 GO:1990716 axonemal central apparatus(GO:1990716)
0.0 0.4 GO:0030061 mitochondrial crista(GO:0030061)
0.0 0.1 GO:0097447 dendritic tree(GO:0097447)
0.0 0.3 GO:0012510 trans-Golgi network transport vesicle membrane(GO:0012510)
0.0 0.2 GO:0005688 U6 snRNP(GO:0005688)
0.0 0.5 GO:0002080 acrosomal membrane(GO:0002080)
0.0 0.2 GO:0097542 ciliary tip(GO:0097542)
0.0 0.3 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.0 2.4 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 2.4 GO:0016749 5-aminolevulinate synthase activity(GO:0003870) N-succinyltransferase activity(GO:0016749)
0.5 1.6 GO:0004605 phosphatidate cytidylyltransferase activity(GO:0004605)
0.5 3.0 GO:0034988 Fc-gamma receptor I complex binding(GO:0034988)
0.4 1.3 GO:0047291 lactosylceramide alpha-2,3-sialyltransferase activity(GO:0047291)
0.4 1.2 GO:0030226 apolipoprotein receptor activity(GO:0030226) apolipoprotein A-I receptor activity(GO:0034188) phosphatidylserine-translocating ATPase activity(GO:0090556)
0.3 0.8 GO:0003692 left-handed Z-DNA binding(GO:0003692)
0.2 1.9 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.2 2.0 GO:0036374 glutathione hydrolase activity(GO:0036374)
0.2 1.1 GO:0019808 polyamine binding(GO:0019808)
0.1 0.4 GO:0003881 CDP-diacylglycerol-inositol 3-phosphatidyltransferase activity(GO:0003881)
0.1 0.4 GO:0005169 neurotrophin TRKB receptor binding(GO:0005169)
0.1 0.5 GO:0004574 oligo-1,6-glucosidase activity(GO:0004574)
0.1 1.1 GO:0004064 arylesterase activity(GO:0004064)
0.1 0.8 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.1 0.3 GO:0004802 transketolase activity(GO:0004802)
0.1 1.2 GO:0030274 LIM domain binding(GO:0030274)
0.1 0.2 GO:0005174 CD40 receptor binding(GO:0005174)
0.1 0.5 GO:0008294 calcium- and calmodulin-responsive adenylate cyclase activity(GO:0008294)
0.1 1.3 GO:0004862 cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.0 1.3 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 1.2 GO:0030275 LRR domain binding(GO:0030275)
0.0 0.9 GO:0003688 DNA replication origin binding(GO:0003688)
0.0 0.1 GO:0071820 N-box binding(GO:0071820)
0.0 0.5 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.0 0.5 GO:0086080 protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
0.0 3.0 GO:0070888 E-box binding(GO:0070888)
0.0 0.5 GO:0005412 glucose:sodium symporter activity(GO:0005412)
0.0 0.4 GO:0016427 tRNA (cytosine) methyltransferase activity(GO:0016427)
0.0 1.2 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.0 0.1 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.0 0.4 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.0 0.2 GO:0070915 lysophosphatidic acid receptor activity(GO:0070915)
0.0 0.3 GO:0015562 efflux transmembrane transporter activity(GO:0015562)
0.0 0.2 GO:0070699 type II activin receptor binding(GO:0070699)
0.0 0.2 GO:0015616 DNA translocase activity(GO:0015616)
0.0 1.0 GO:0071949 FAD binding(GO:0071949)
0.0 0.1 GO:0004816 asparagine-tRNA ligase activity(GO:0004816)
0.0 1.5 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.0 0.1 GO:0001093 TFIIB-class transcription factor binding(GO:0001093)
0.0 0.2 GO:0004013 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.0 0.3 GO:0032050 clathrin heavy chain binding(GO:0032050)
0.0 0.6 GO:0097602 cullin family protein binding(GO:0097602)
0.0 0.2 GO:0008046 axon guidance receptor activity(GO:0008046)
0.0 0.3 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 1.1 GO:0004601 peroxidase activity(GO:0004601)
0.0 0.1 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.0 0.2 GO:0000900 translation repressor activity, nucleic acid binding(GO:0000900)
0.0 0.2 GO:0004383 guanylate cyclase activity(GO:0004383)
0.0 5.7 GO:0045296 cadherin binding(GO:0045296)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.0 PID WNT NONCANONICAL PATHWAY Noncanonical Wnt signaling pathway
0.0 0.6 PID FGF PATHWAY FGF signaling pathway
0.0 3.2 PID E2F PATHWAY E2F transcription factor network
0.0 1.9 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.0 0.9 PID ATR PATHWAY ATR signaling pathway
0.0 0.5 PID LPA4 PATHWAY LPA4-mediated signaling events
0.0 0.8 PID IL8 CXCR2 PATHWAY IL8- and CXCR2-mediated signaling events
0.0 0.8 PID PLK1 PATHWAY PLK1 signaling events
0.0 0.4 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.0 0.3 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.4 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.1 0.8 REACTOME HORMONE LIGAND BINDING RECEPTORS Genes involved in Hormone ligand-binding receptors
0.0 1.2 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.0 0.9 REACTOME PHOSPHORYLATION OF THE APC C Genes involved in Phosphorylation of the APC/C
0.0 2.0 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.0 0.5 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0 0.5 REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY Genes involved in Adenylate cyclase activating pathway
0.0 0.8 REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
0.0 0.5 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.0 0.3 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.0 0.9 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0 0.3 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.0 0.6 REACTOME INTERFERON GAMMA SIGNALING Genes involved in Interferon gamma signaling
0.0 0.2 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.0 0.3 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport
0.0 0.6 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0 1.3 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.0 0.2 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease