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GSE58827: Dynamics of the Mouse Liver

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Results for Mbd2

Z-value: 0.95

Motif logo

Transcription factors associated with Mbd2

Gene Symbol Gene ID Gene Info
ENSMUSG00000024513.17 methyl-CpG binding domain protein 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Mbd2mm39_v1_chr18_+_70701260_70701469-0.828.9e-10Click!

Activity profile of Mbd2 motif

Sorted Z-values of Mbd2 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr7_+_65511777 3.90 ENSMUST00000055576.12
ENSMUST00000098391.11
proprotein convertase subtilisin/kexin type 6
chr12_+_87194476 2.80 ENSMUST00000063117.10
ENSMUST00000220574.2
glutathione transferase zeta 1 (maleylacetoacetate isomerase)
chr12_-_102671154 2.70 ENSMUST00000178697.2
ENSMUST00000046518.12
inositol 1,3,4-triphosphate 5/6 kinase
chr5_-_53370761 2.59 ENSMUST00000031090.8
sel-1 suppressor of lin-12-like 3 (C. elegans)
chr2_+_27567213 2.40 ENSMUST00000077257.12
retinoid X receptor alpha
chr15_-_31367668 2.39 ENSMUST00000110410.10
ENSMUST00000076942.5
ankyrin repeat domain 33B
chr15_-_31367872 2.36 ENSMUST00000123325.9
ankyrin repeat domain 33B
chr8_-_71834543 2.24 ENSMUST00000002466.9
nuclear receptor subfamily 2, group F, member 6
chr7_+_86895851 2.18 ENSMUST00000032781.14
NADPH oxidase 4
chr7_+_65511482 2.12 ENSMUST00000176199.8
proprotein convertase subtilisin/kexin type 6
chr16_-_20534851 2.10 ENSMUST00000120099.8
ENSMUST00000232309.2
ENSMUST00000007207.15
chloride channel, voltage-sensitive 2
chr16_-_10360893 2.08 ENSMUST00000184863.8
ENSMUST00000038281.6
dexamethasone-induced transcript
chr3_+_89680867 2.00 ENSMUST00000038356.13
ubiquitin-conjugating enzyme E2Q family member 1
chr12_+_87193922 2.00 ENSMUST00000222885.2
glutathione transferase zeta 1 (maleylacetoacetate isomerase)
chr13_-_53135064 2.00 ENSMUST00000071065.8
nuclear factor, interleukin 3, regulated
chr15_-_85918378 1.87 ENSMUST00000016172.10
cadherin, EGF LAG seven-pass G-type receptor 1
chr5_+_30971915 1.83 ENSMUST00000031058.15
microtubule-associated protein, RP/EB family, member 3
chr2_+_27567246 1.82 ENSMUST00000166775.8
retinoid X receptor alpha
chr17_+_34250757 1.82 ENSMUST00000044858.16
ENSMUST00000174299.9
retinoid X receptor beta
chr15_-_76540916 1.81 ENSMUST00000229524.2
cysteine and histidine rich 1
chr5_+_30972067 1.81 ENSMUST00000200692.4
microtubule-associated protein, RP/EB family, member 3
chr13_-_55510595 1.77 ENSMUST00000021940.8
lectin, mannose-binding 2
chr7_-_126625739 1.73 ENSMUST00000205461.2
MYC-associated zinc finger protein (purine-binding transcription factor)
chr17_+_34251041 1.72 ENSMUST00000173354.9
retinoid X receptor beta
chr19_+_6291698 1.67 ENSMUST00000045351.13
autophagy related 2A
chr12_-_87194658 1.67 ENSMUST00000037788.6
protein-O-mannosyltransferase 2
chr2_-_6327884 1.64 ENSMUST00000238876.2
RIKEN cDNA 1700014B07 gene
chr3_-_121608809 1.56 ENSMUST00000197383.5
ATP-binding cassette, sub-family D (ALD), member 3
chr2_-_160714473 1.56 ENSMUST00000103111.9
zinc fingers and homeoboxes 3
chr4_-_155430153 1.54 ENSMUST00000103178.11
protein kinase C, zeta
chr5_+_54155814 1.53 ENSMUST00000117661.9
stromal interaction molecule 2
chr7_-_126625657 1.51 ENSMUST00000205568.2
MYC-associated zinc finger protein (purine-binding transcription factor)
chr12_-_108241597 1.50 ENSMUST00000222310.2
coiled-coil domain containing 85C
chr11_-_89193158 1.49 ENSMUST00000061728.5
noggin
chr3_-_121608859 1.47 ENSMUST00000029770.8
ATP-binding cassette, sub-family D (ALD), member 3
chr7_-_127307898 1.47 ENSMUST00000207019.2
B cell CLL/lymphoma 7C
chr7_+_86895996 1.47 ENSMUST00000068829.13
NADPH oxidase 4
chr11_-_107685383 1.46 ENSMUST00000021066.4
calcium channel, voltage-dependent, gamma subunit 4
chr13_+_49340961 1.46 ENSMUST00000049022.15
ninjurin 1
chr8_+_112263255 1.44 ENSMUST00000171182.8
ENSMUST00000168428.8
zinc and ring finger 1
chr10_-_31321793 1.41 ENSMUST00000213639.2
ENSMUST00000215515.2
ENSMUST00000214644.2
ENSMUST00000213528.2
tumor protein D52-like 1
chr1_+_74430575 1.39 ENSMUST00000027367.14
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1
chr12_+_17316546 1.39 ENSMUST00000057288.7
ENSMUST00000239402.2
protein disulfide isomerase associated 6
chr12_-_107969673 1.38 ENSMUST00000109887.8
ENSMUST00000109891.3
B cell leukemia/lymphoma 11B
chr5_+_54155871 1.38 ENSMUST00000201469.4
stromal interaction molecule 2
chr11_-_106811507 1.38 ENSMUST00000103067.10
SMAD specific E3 ubiquitin protein ligase 2
chr7_+_29931309 1.37 ENSMUST00000019882.16
ENSMUST00000149654.8
polymerase (RNA) II (DNA directed) polypeptide I
chr13_+_49340995 1.37 ENSMUST00000120733.8
ninjurin 1
chr2_+_78699360 1.37 ENSMUST00000028398.14
ubiquitin-conjugating enzyme E2E 3
chr15_+_87509413 1.32 ENSMUST00000068088.8
TAFA chemokine like family member 5
chr2_-_27365612 1.31 ENSMUST00000147736.2
bromodomain containing 3
chr14_+_122712809 1.30 ENSMUST00000075888.6
zinc finger protein of the cerebellum 2
chr7_-_127308059 1.29 ENSMUST00000061468.9
B cell CLL/lymphoma 7C
chr2_+_155849965 1.27 ENSMUST00000006035.13
ERGIC and golgi 3
chr10_-_53951796 1.27 ENSMUST00000105470.9
mannosidase 1, alpha
chr5_+_37025926 1.26 ENSMUST00000201156.2
protein phosphatase 2, regulatory subunit B, gamma
chr2_+_155850002 1.25 ENSMUST00000088650.11
ERGIC and golgi 3
chr7_-_74204222 1.25 ENSMUST00000134539.2
ENSMUST00000026897.14
ENSMUST00000098371.9
solute carrier organic anion transporter family, member 3a1
chr18_-_25301729 1.24 ENSMUST00000148255.8
tubulin polyglutamylase complex subunit 2
chr9_-_110571645 1.23 ENSMUST00000006005.12
parathyroid hormone 1 receptor
chr4_-_3938352 1.22 ENSMUST00000003369.10
pleiomorphic adenoma gene 1
chr8_+_112263632 1.22 ENSMUST00000173506.8
zinc and ring finger 1
chr9_+_80072274 1.22 ENSMUST00000035889.15
ENSMUST00000113268.8
myosin VI
chr8_+_112263465 1.21 ENSMUST00000095176.12
zinc and ring finger 1
chr14_+_45457168 1.21 ENSMUST00000227086.2
ENSMUST00000147957.2
G protein-coupled receptor 137C
chr11_-_86884507 1.21 ENSMUST00000018571.5
yippee like 2
chr14_-_20844074 1.19 ENSMUST00000080440.14
ENSMUST00000100837.11
ENSMUST00000071816.7
calcium/calmodulin-dependent protein kinase II gamma
chr18_+_84106188 1.17 ENSMUST00000060223.4
zinc binding alcohol dehydrogenase, domain containing 2
chr2_+_155617251 1.16 ENSMUST00000029141.6
matrix metallopeptidase 24
chr1_+_106099482 1.15 ENSMUST00000061047.7
PH domain and leucine rich repeat protein phosphatase 1
chr11_+_87507977 1.15 ENSMUST00000093956.4
heat shock transcription factor family member 5
chr9_+_43655230 1.12 ENSMUST00000034510.9
nectin cell adhesion molecule 1
chr18_-_16942289 1.11 ENSMUST00000025166.14
cadherin 2
chr5_+_37025810 1.11 ENSMUST00000031003.11
protein phosphatase 2, regulatory subunit B, gamma
chr4_-_120604445 1.09 ENSMUST00000030376.8
potassium voltage-gated channel, subfamily Q, member 4
chr10_-_31485180 1.08 ENSMUST00000081989.8
ring finger protein 217
chr2_+_32536594 1.07 ENSMUST00000113272.8
ENSMUST00000009705.14
ENSMUST00000167841.8
endoglin
chr1_+_91729175 1.05 ENSMUST00000007949.4
ENSMUST00000186075.2
twist basic helix-loop-helix transcription factor 2
chr19_+_4147391 1.05 ENSMUST00000174514.2
ENSMUST00000174149.8
CDK2-associated protein 2
chr16_-_4238280 1.03 ENSMUST00000120080.8
adenylate cyclase 9
chr8_-_123980825 1.02 ENSMUST00000118279.2
VPS9 domain containing 1
chr11_+_108811626 1.01 ENSMUST00000140821.2
axin 2
chr15_+_74435587 1.00 ENSMUST00000185682.7
ENSMUST00000170845.8
ENSMUST00000187599.2
adhesion G protein-coupled receptor B1
chr4_+_152423344 0.99 ENSMUST00000005175.5
chromodomain helicase DNA binding protein 5
chr10_+_127216459 0.98 ENSMUST00000166820.8
R3H domain containing 2
chr2_-_94236991 0.98 ENSMUST00000111237.9
ENSMUST00000094801.5
ENSMUST00000111238.8
tetratricopeptide repeat domain 17
chr2_-_155849839 0.96 ENSMUST00000086145.10
ENSMUST00000144686.8
ENSMUST00000140657.8
RIKEN cDNA 6430550D23 gene
chr10_+_127216668 0.95 ENSMUST00000111628.9
R3H domain containing 2
chr12_-_108241392 0.95 ENSMUST00000136175.3
coiled-coil domain containing 85C
chr18_-_25302064 0.94 ENSMUST00000115817.3
tubulin polyglutamylase complex subunit 2
chr7_-_127307791 0.92 ENSMUST00000205977.2
B cell CLL/lymphoma 7C
chr12_-_101942172 0.92 ENSMUST00000221191.2
NADH:ubiquinone oxidoreductase subunit B1
chr10_-_77738300 0.91 ENSMUST00000057608.5
leucine rich repeat containing 3
chrX_+_160500623 0.91 ENSMUST00000061514.8
retinoic acid induced 2
chrX_+_150127171 0.90 ENSMUST00000073364.6
family with sequence similarity 120, member C
chr7_-_46782448 0.90 ENSMUST00000033142.13
protein tyrosine phosphatase, non-receptor type 5
chr14_-_70757601 0.89 ENSMUST00000022693.9
bone morphogenetic protein 1
chr1_+_74640706 0.89 ENSMUST00000087186.11
serine/threonine kinase 36
chr8_-_123980908 0.88 ENSMUST00000122363.8
VPS9 domain containing 1
chr11_+_97554192 0.88 ENSMUST00000044730.12
myeloid/lymphoid or mixed-lineage leukemia; translocated to, 6
chr7_+_141503719 0.87 ENSMUST00000105989.9
ENSMUST00000075528.12
ENSMUST00000174499.8
BR serine/threonine kinase 2
chr17_+_83522700 0.87 ENSMUST00000170794.8
protein kinase domain containing, cytoplasmic
chr1_+_91226058 0.86 ENSMUST00000027532.13
selenocysteine lyase
chr8_-_125161061 0.85 ENSMUST00000140012.8
piggyBac transposable element derived 5
chr14_-_39194782 0.85 ENSMUST00000168810.9
ENSMUST00000173780.2
ENSMUST00000166968.9
neuregulin 3
chr10_-_81266800 0.84 ENSMUST00000117966.2
nuclear factor I/C
chr2_+_157756535 0.84 ENSMUST00000109523.2
V-set and transmembrane domain containing 2-like
chr6_-_122463316 0.84 ENSMUST00000205114.2
ribosomal modification protein rimK-like family member B
chr9_+_80072361 0.84 ENSMUST00000184480.8
myosin VI
chr18_+_77861656 0.84 ENSMUST00000114748.2
ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1
chr18_+_69479211 0.83 ENSMUST00000201235.4
transcription factor 4
chr12_-_99359265 0.83 ENSMUST00000177451.8
forkhead box N3
chr2_-_160714749 0.83 ENSMUST00000176141.8
zinc fingers and homeoboxes 3
chr4_-_43669141 0.82 ENSMUST00000056474.7
family with sequence similarity 221, member B
chr7_-_139162706 0.81 ENSMUST00000106095.3
NK6 homeobox 2
chr1_+_74640590 0.80 ENSMUST00000087183.11
ENSMUST00000148456.8
ENSMUST00000113694.8
serine/threonine kinase 36
chr4_+_109835224 0.80 ENSMUST00000061187.4
doublesex and mab-3 related transcription factor like family A2
chr4_+_132766793 0.80 ENSMUST00000105914.2
AT hook, DNA binding motif, containing 1
chr11_+_116809669 0.80 ENSMUST00000103027.10
mannoside acetylglucosaminyltransferase 5, isoenzyme B
chr14_-_29443792 0.79 ENSMUST00000022567.9
calcium channel, voltage-dependent, alpha2/delta subunit 3
chr11_-_5394838 0.78 ENSMUST00000109867.8
ENSMUST00000143746.3
zinc and ring finger 3
chr14_+_34542053 0.78 ENSMUST00000043349.7
glutamate receptor, ionotropic, delta 1
chr15_-_76541105 0.78 ENSMUST00000176274.2
cysteine and histidine rich 1
chr19_+_8875459 0.78 ENSMUST00000096246.5
ENSMUST00000235274.2
alpha glucosidase 2 alpha neutral subunit
chr7_+_4693603 0.77 ENSMUST00000120836.8
BR serine/threonine kinase 1
chr5_-_115332343 0.77 ENSMUST00000112113.8
calcium binding protein 1
chr11_+_77928736 0.77 ENSMUST00000072289.12
ENSMUST00000100784.9
ENSMUST00000073660.7
flotillin 2
chr11_+_108811168 0.77 ENSMUST00000052915.14
axin 2
chr10_+_127000991 0.77 ENSMUST00000006914.11
beta-1,4-N-acetyl-galactosaminyl transferase 1
chr7_+_141503411 0.76 ENSMUST00000078200.12
ENSMUST00000018971.15
BR serine/threonine kinase 2
chr5_-_24556602 0.76 ENSMUST00000036092.10
potassium voltage-gated channel, subfamily H (eag-related), member 2
chr2_-_160714904 0.75 ENSMUST00000109460.8
ENSMUST00000127201.2
zinc fingers and homeoboxes 3
chr2_-_29142965 0.75 ENSMUST00000155949.2
ENSMUST00000154682.8
ENSMUST00000028141.6
ENSMUST00000071201.5
RIKEN cDNA 6530402F18 gene
netrin G2
chr7_+_4693759 0.74 ENSMUST00000048248.9
BR serine/threonine kinase 1
chr9_+_108569315 0.74 ENSMUST00000035220.12
protein kinase, cAMP dependent regulatory, type II alpha
chr10_-_127502541 0.72 ENSMUST00000026469.9
Ngfi-A binding protein 2
chr2_-_166838018 0.72 ENSMUST00000049412.12
staufen double-stranded RNA binding protein 1
chr2_-_173118315 0.71 ENSMUST00000036248.13
prostate transmembrane protein, androgen induced 1
chr17_+_35643853 0.70 ENSMUST00000113879.4
histocompatibility 2, Q region locus 6
chr6_+_124908439 0.70 ENSMUST00000032214.14
myeloid leukemia factor 2
chr4_+_129878627 0.70 ENSMUST00000120204.8
adhesion G protein-coupled receptor B2
chr15_+_89407954 0.70 ENSMUST00000230807.2
SH3 and multiple ankyrin repeat domains 3
chr2_+_139520098 0.68 ENSMUST00000184404.8
ENSMUST00000099307.4
isthmin 1, angiogenesis inhibitor
chr7_+_141503583 0.67 ENSMUST00000172652.8
BR serine/threonine kinase 2
chr2_-_166838182 0.67 ENSMUST00000109238.9
ENSMUST00000109235.8
ENSMUST00000109236.9
staufen double-stranded RNA binding protein 1
chr15_+_68800546 0.67 ENSMUST00000230847.2
KH domain containing, RNA binding, signal transduction associated 3
chr1_-_165830160 0.67 ENSMUST00000111429.11
ENSMUST00000176800.2
ENSMUST00000177358.8
POU domain, class 2, transcription factor 1
chr2_+_157120946 0.66 ENSMUST00000116380.9
ENSMUST00000029171.6
ribophorin II
chr2_+_179813278 0.66 ENSMUST00000061437.5
adhesion regulating molecule 1
chr19_-_10502468 0.65 ENSMUST00000025570.8
ENSMUST00000236455.2
succinate dehydrogenase complex assembly factor 2
chr8_+_93687561 0.65 ENSMUST00000072939.8
solute carrier family 6 (neurotransmitter transporter, noradrenalin), member 2
chr11_-_35871300 0.65 ENSMUST00000018993.7
WW, C2 and coiled-coil domain containing 1
chr9_+_26645141 0.64 ENSMUST00000115269.9
beta-1,3-glucuronyltransferase 1 (glucuronosyltransferase P)
chr17_+_35643818 0.64 ENSMUST00000174699.8
histocompatibility 2, Q region locus 6
chr19_+_11943265 0.63 ENSMUST00000025590.11
oxysterol binding protein
chr11_-_106378622 0.63 ENSMUST00000001059.9
ENSMUST00000106799.2
ENSMUST00000106800.2
endoplasmic reticulum (ER) to nucleus signalling 1
chr12_-_107969853 0.63 ENSMUST00000066060.11
B cell leukemia/lymphoma 11B
chr19_-_47452557 0.63 ENSMUST00000111800.4
SH3 and PX domains 2A
chr15_+_80118219 0.63 ENSMUST00000023048.12
mitochondrial elongation factor 1
chr19_-_10502546 0.63 ENSMUST00000237827.2
succinate dehydrogenase complex assembly factor 2
chr7_-_64806164 0.62 ENSMUST00000148459.3
ENSMUST00000119118.8
family with sequence similarity 189, member A1
chr6_+_6863769 0.62 ENSMUST00000031768.8
distal-less homeobox 6
chr4_+_43669266 0.62 ENSMUST00000107864.8
transmembrane protein 8B
chr12_-_111679379 0.62 ENSMUST00000160825.2
ENSMUST00000162953.2
BCL2-associated athanogene 5
chrX_+_160500051 0.62 ENSMUST00000112338.2
retinoic acid induced 2
chr1_-_38168801 0.61 ENSMUST00000195383.2
REV1, DNA directed polymerase
chr7_-_125681577 0.61 ENSMUST00000073935.7
GSG1-like
chr3_-_108133914 0.61 ENSMUST00000141387.4
synaptophysin-like 2
chr11_-_120515799 0.61 ENSMUST00000106183.3
ENSMUST00000080202.12
sirtuin 7
chr7_-_136915602 0.61 ENSMUST00000210774.2
early B cell factor 3
chr2_-_84717036 0.61 ENSMUST00000054514.6
ENSMUST00000151799.8
reticulon 4 receptor-like 2
chr18_+_69478893 0.60 ENSMUST00000202354.4
transcription factor 4
chr7_+_29003363 0.60 ENSMUST00000108231.8
D4, zinc and double PHD fingers family 1
chr1_+_40720731 0.60 ENSMUST00000192345.2
solute carrier family 9 (sodium/hydrogen exchanger), member 2
chr17_-_16046780 0.60 ENSMUST00000232638.2
ENSMUST00000170578.3
repulsive guidance molecule family member B
chr15_+_34837501 0.60 ENSMUST00000072868.5
K+ voltage-gated channel, subfamily S, 2
chr9_+_26645024 0.60 ENSMUST00000160899.8
ENSMUST00000161431.3
ENSMUST00000159799.8
beta-1,3-glucuronyltransferase 1 (glucuronosyltransferase P)
chr8_-_88199231 0.59 ENSMUST00000034076.16
cerebellin 1 precursor protein
chr4_+_129878890 0.59 ENSMUST00000106017.8
ENSMUST00000121049.8
adhesion G protein-coupled receptor B2
chr1_+_74894069 0.59 ENSMUST00000160379.4
cyclin-dependent kinase 5, regulatory subunit 2 (p39)
chr15_-_53209513 0.59 ENSMUST00000077273.9
exostosin glycosyltransferase 1
chr15_+_74388044 0.59 ENSMUST00000042035.16
adhesion G protein-coupled receptor B1
chr7_-_37470184 0.58 ENSMUST00000176680.8
zinc finger protein 536
chr7_+_29979512 0.58 ENSMUST00000108187.8
ENSMUST00000014072.6
RIKEN cDNA 1700020L13 gene
chr11_-_61157986 0.58 ENSMUST00000066277.10
ENSMUST00000074127.14
ENSMUST00000108715.3
aldehyde dehydrogenase family 3, subfamily A2
chr2_+_156455583 0.57 ENSMUST00000109567.10
ENSMUST00000169464.9
DLG associated protein 4
chr5_+_114706077 0.57 ENSMUST00000043650.8
family with sequence similarity 222, member A
chr6_+_124908341 0.57 ENSMUST00000203021.3
myeloid leukemia factor 2
chr4_-_57300361 0.57 ENSMUST00000153926.8
protein tyrosine phosphatase, non-receptor type 3
chr7_-_99629637 0.57 ENSMUST00000080817.6
ring finger protein 169
chr6_-_72876269 0.57 ENSMUST00000204598.3
potassium channel modulatory factor 1
chr4_+_152423075 0.56 ENSMUST00000030775.12
ENSMUST00000164662.8
chromodomain helicase DNA binding protein 5
chr5_-_138981842 0.56 ENSMUST00000110897.8
platelet derived growth factor, alpha
chr5_-_108697857 0.56 ENSMUST00000129040.2
ENSMUST00000046892.10
complexin 1
chr12_-_5425682 0.56 ENSMUST00000020958.9
kelch-like 29
chr4_-_149858694 0.55 ENSMUST00000105686.3
solute carrier family 25, member 33
chr7_-_126625617 0.54 ENSMUST00000032916.6
MYC-associated zinc finger protein (purine-binding transcription factor)
chr13_-_120252229 0.54 ENSMUST00000223812.2
zinc finger protein 131
chr10_-_17898838 0.54 ENSMUST00000220433.2
ABRA C-terminal like
chr15_+_76215488 0.54 ENSMUST00000172281.8
GPI anchor attachment protein 1

Network of associatons between targets according to the STRING database.

First level regulatory network of Mbd2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 6.0 GO:0032902 nerve growth factor production(GO:0032902)
0.9 3.6 GO:1903033 regulation of microtubule plus-end binding(GO:1903031) positive regulation of microtubule plus-end binding(GO:1903033)
0.8 4.2 GO:0006447 regulation of translational initiation by iron(GO:0006447) positive regulation of translational initiation by iron(GO:0045994)
0.8 3.0 GO:0015910 peroxisomal long-chain fatty acid import(GO:0015910)
0.7 2.0 GO:0097535 lymphoid lineage cell migration(GO:0097534) lymphoid lineage cell migration into thymus(GO:0097535)
0.6 1.9 GO:0060448 dichotomous subdivision of terminal units involved in lung branching(GO:0060448)
0.5 4.8 GO:0006572 tyrosine catabolic process(GO:0006572)
0.5 1.5 GO:0060300 regulation of cytokine activity(GO:0060300) fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060825) negative regulation of epithelial to mesenchymal transition involved in endocardial cushion formation(GO:1905006) regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:2000313)
0.4 1.7 GO:0007228 positive regulation of hh target transcription factor activity(GO:0007228)
0.4 2.9 GO:0032237 activation of store-operated calcium channel activity(GO:0032237)
0.4 1.1 GO:0003032 detection of oxygen(GO:0003032) cardiac jelly development(GO:1905072)
0.3 2.0 GO:0070459 prolactin secretion(GO:0070459)
0.3 1.3 GO:1900224 positive regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry(GO:1900224)
0.3 1.3 GO:0034553 respiratory chain complex II assembly(GO:0034552) mitochondrial respiratory chain complex II assembly(GO:0034553) mitochondrial respiratory chain complex II biogenesis(GO:0097032)
0.3 3.3 GO:0006369 termination of RNA polymerase II transcription(GO:0006369)
0.3 1.8 GO:0061181 regulation of mismatch repair(GO:0032423) regulation of chondrocyte development(GO:0061181) negative regulation of Wnt signaling pathway involved in dorsal/ventral axis specification(GO:2000054)
0.3 0.9 GO:2001160 regulation of histone H3-K79 methylation(GO:2001160)
0.3 0.8 GO:0038018 Wnt receptor catabolic process(GO:0038018)
0.2 1.7 GO:1904098 regulation of protein O-linked glycosylation(GO:1904098) positive regulation of protein O-linked glycosylation(GO:1904100)
0.2 1.2 GO:1901165 positive regulation of trophoblast cell migration(GO:1901165)
0.2 1.9 GO:0098532 histone H3-K27 trimethylation(GO:0098532)
0.2 1.4 GO:0046726 positive regulation by virus of viral protein levels in host cell(GO:0046726)
0.2 0.9 GO:2001025 positive regulation of response to drug(GO:2001025)
0.2 1.5 GO:2000667 positive regulation of interleukin-5 secretion(GO:2000664) positive regulation of interleukin-13 secretion(GO:2000667)
0.2 1.2 GO:0010991 negative regulation of SMAD protein complex assembly(GO:0010991)
0.2 1.2 GO:0021773 striatal medium spiny neuron differentiation(GO:0021773)
0.2 0.6 GO:1903173 sesquiterpenoid metabolic process(GO:0006714) phytol metabolic process(GO:0033306) fatty alcohol metabolic process(GO:1903173)
0.2 2.1 GO:0060689 cell differentiation involved in salivary gland development(GO:0060689)
0.2 0.8 GO:1902303 negative regulation of potassium ion export(GO:1902303)
0.2 0.6 GO:0010512 negative regulation of phosphatidylinositol biosynthetic process(GO:0010512)
0.2 0.5 GO:0051385 response to mineralocorticoid(GO:0051385)
0.2 0.7 GO:0060399 positive regulation of growth hormone receptor signaling pathway(GO:0060399)
0.2 0.5 GO:0035526 retrograde transport, plasma membrane to Golgi(GO:0035526)
0.2 1.4 GO:0061303 cornea development in camera-type eye(GO:0061303)
0.2 0.3 GO:0016332 establishment or maintenance of polarity of embryonic epithelium(GO:0016332)
0.2 1.1 GO:0032227 negative regulation of synaptic transmission, dopaminergic(GO:0032227)
0.2 0.6 GO:0045897 regulation of transcription during mitosis(GO:0045896) positive regulation of transcription during mitosis(GO:0045897)
0.1 3.0 GO:0060033 anatomical structure regression(GO:0060033)
0.1 0.6 GO:0021586 pons maturation(GO:0021586)
0.1 0.4 GO:0015881 creatine transport(GO:0015881)
0.1 1.2 GO:0090038 negative regulation of protein kinase C signaling(GO:0090038)
0.1 0.9 GO:0060596 mammary placode formation(GO:0060596)
0.1 1.2 GO:0016480 negative regulation of transcription from RNA polymerase III promoter(GO:0016480)
0.1 1.2 GO:0060732 positive regulation of inositol phosphate biosynthetic process(GO:0060732)
0.1 0.8 GO:0021912 regulation of transcription from RNA polymerase II promoter involved in spinal cord motor neuron fate specification(GO:0021912) regulation of transcription from RNA polymerase II promoter involved in ventral spinal cord interneuron specification(GO:0021913)
0.1 3.6 GO:0050667 homocysteine metabolic process(GO:0050667)
0.1 2.7 GO:0032957 inositol trisphosphate metabolic process(GO:0032957)
0.1 3.4 GO:0050965 detection of temperature stimulus involved in sensory perception(GO:0050961) detection of temperature stimulus involved in sensory perception of pain(GO:0050965)
0.1 0.8 GO:0044860 protein localization to plasma membrane raft(GO:0044860) regulation of establishment of T cell polarity(GO:1903903)
0.1 0.4 GO:0097065 anterior head development(GO:0097065) regulation of anterior head development(GO:2000742) positive regulation of anterior head development(GO:2000744)
0.1 0.5 GO:0003221 right ventricular cardiac muscle tissue morphogenesis(GO:0003221)
0.1 1.4 GO:0006283 transcription-coupled nucleotide-excision repair(GO:0006283)
0.1 0.9 GO:0090005 negative regulation of Golgi to plasma membrane protein transport(GO:0042997) negative regulation of establishment of protein localization to plasma membrane(GO:0090005)
0.1 0.9 GO:0070055 activation of signaling protein activity involved in unfolded protein response(GO:0006987) mRNA splicing via endonucleolytic cleavage and ligation involved in unfolded protein response(GO:0030969) mRNA splicing, via endonucleolytic cleavage and ligation(GO:0070054) mRNA endonucleolytic cleavage involved in unfolded protein response(GO:0070055)
0.1 0.5 GO:1903764 regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization(GO:1903760) regulation of potassium ion export across plasma membrane(GO:1903764) regulation of membrane repolarization during ventricular cardiac muscle cell action potential(GO:1905024)
0.1 0.9 GO:0016259 selenocysteine metabolic process(GO:0016259)
0.1 0.3 GO:0030860 regulation of polarized epithelial cell differentiation(GO:0030860)
0.1 0.6 GO:0072531 pyrimidine-containing compound transmembrane transport(GO:0072531)
0.1 2.1 GO:0071257 cellular response to electrical stimulus(GO:0071257)
0.1 2.4 GO:0070262 peptidyl-serine dephosphorylation(GO:0070262)
0.1 0.3 GO:0098928 presynaptic signal transduction(GO:0098928) presynapse to nucleus signaling pathway(GO:0099526)
0.1 1.5 GO:0002934 desmosome organization(GO:0002934)
0.1 1.7 GO:1900454 positive regulation of long term synaptic depression(GO:1900454)
0.1 1.1 GO:0097118 neuroligin clustering involved in postsynaptic membrane assembly(GO:0097118)
0.1 1.3 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.1 4.0 GO:0055012 ventricular cardiac muscle cell differentiation(GO:0055012)
0.1 0.7 GO:0030910 olfactory placode formation(GO:0030910) olfactory placode development(GO:0071698) olfactory placode morphogenesis(GO:0071699)
0.1 2.4 GO:2000311 regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000311)
0.1 0.4 GO:1905051 regulation of base-excision repair(GO:1905051) positive regulation of base-excision repair(GO:1905053)
0.1 0.5 GO:0060024 rhythmic synaptic transmission(GO:0060024)
0.1 0.6 GO:0061084 negative regulation of protein refolding(GO:0061084)
0.1 0.2 GO:0033693 neurofilament bundle assembly(GO:0033693)
0.1 1.0 GO:0072675 osteoclast fusion(GO:0072675)
0.1 2.0 GO:0006491 N-glycan processing(GO:0006491)
0.1 0.5 GO:0016255 attachment of GPI anchor to protein(GO:0016255)
0.1 0.4 GO:0051562 negative regulation of mitochondrial calcium ion concentration(GO:0051562)
0.1 0.3 GO:0048104 establishment of body hair or bristle planar orientation(GO:0048104) establishment of body hair planar orientation(GO:0048105)
0.1 1.2 GO:0006857 oligopeptide transport(GO:0006857)
0.1 0.7 GO:0051045 negative regulation of membrane protein ectodomain proteolysis(GO:0051045)
0.1 0.6 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.1 0.3 GO:0044727 DNA demethylation of male pronucleus(GO:0044727)
0.1 0.2 GO:0070634 transepithelial ammonium transport(GO:0070634)
0.1 0.2 GO:0000160 phosphorelay signal transduction system(GO:0000160)
0.1 5.4 GO:0070936 protein K48-linked ubiquitination(GO:0070936)
0.1 1.7 GO:0044804 nucleophagy(GO:0044804)
0.1 2.0 GO:0071353 cellular response to interleukin-4(GO:0071353)
0.1 0.5 GO:0051534 negative regulation of NFAT protein import into nucleus(GO:0051534)
0.1 0.6 GO:0098719 sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.1 0.4 GO:0035106 operant conditioning(GO:0035106)
0.1 0.3 GO:0033353 S-adenosylmethionine cycle(GO:0033353)
0.1 1.1 GO:2000035 regulation of stem cell division(GO:2000035)
0.1 0.4 GO:0044821 meiotic telomere tethering at nuclear periphery(GO:0044821) meiotic attachment of telomere to nuclear envelope(GO:0070197) chromosome attachment to the nuclear envelope(GO:0097240)
0.0 1.3 GO:0042118 endothelial cell activation(GO:0042118)
0.0 0.2 GO:0014886 transition between slow and fast fiber(GO:0014886)
0.0 0.2 GO:0060800 regulation of cell differentiation involved in embryonic placenta development(GO:0060800)
0.0 1.2 GO:1901897 regulation of relaxation of cardiac muscle(GO:1901897)
0.0 0.2 GO:0010510 regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510) regulation of acyl-CoA biosynthetic process(GO:0050812)
0.0 0.2 GO:0061534 gamma-aminobutyric acid secretion, neurotransmission(GO:0061534)
0.0 0.2 GO:0051835 positive regulation of synapse structural plasticity(GO:0051835)
0.0 0.3 GO:0045200 establishment or maintenance of neuroblast polarity(GO:0045196) establishment of neuroblast polarity(GO:0045200)
0.0 0.2 GO:2000182 regulation of progesterone biosynthetic process(GO:2000182)
0.0 1.0 GO:0060736 prostate gland growth(GO:0060736)
0.0 0.4 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
0.0 0.8 GO:0090141 positive regulation of mitochondrial fission(GO:0090141)
0.0 0.4 GO:0007549 dosage compensation(GO:0007549) dosage compensation by inactivation of X chromosome(GO:0009048)
0.0 0.3 GO:0098712 L-glutamate import across plasma membrane(GO:0098712)
0.0 0.8 GO:0021796 cerebral cortex regionalization(GO:0021796)
0.0 1.2 GO:0036075 endochondral ossification(GO:0001958) replacement ossification(GO:0036075)
0.0 0.9 GO:0071880 adenylate cyclase-activating adrenergic receptor signaling pathway(GO:0071880)
0.0 0.0 GO:0021679 cerebellar molecular layer development(GO:0021679)
0.0 0.1 GO:0086046 membrane depolarization during SA node cell action potential(GO:0086046)
0.0 0.3 GO:0060710 chorio-allantoic fusion(GO:0060710)
0.0 0.8 GO:0097094 craniofacial suture morphogenesis(GO:0097094)
0.0 0.2 GO:0001922 B-1 B cell homeostasis(GO:0001922)
0.0 0.5 GO:0031468 nuclear envelope reassembly(GO:0031468)
0.0 0.2 GO:0060272 embryonic skeletal joint morphogenesis(GO:0060272)
0.0 0.3 GO:2000344 positive regulation of acrosome reaction(GO:2000344)
0.0 0.4 GO:0033564 anterior/posterior axon guidance(GO:0033564)
0.0 1.1 GO:1902259 regulation of delayed rectifier potassium channel activity(GO:1902259)
0.0 2.4 GO:0045669 positive regulation of osteoblast differentiation(GO:0045669)
0.0 0.2 GO:0007354 zygotic determination of anterior/posterior axis, embryo(GO:0007354)
0.0 0.2 GO:0098703 calcium ion import across plasma membrane(GO:0098703) calcium ion import into cell(GO:1990035)
0.0 0.6 GO:0015874 norepinephrine transport(GO:0015874)
0.0 1.4 GO:0043277 apoptotic cell clearance(GO:0043277)
0.0 0.6 GO:0044126 regulation of growth of symbiont in host(GO:0044126)
0.0 0.9 GO:0061036 positive regulation of cartilage development(GO:0061036)
0.0 0.6 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.0 1.3 GO:0002474 antigen processing and presentation of peptide antigen via MHC class I(GO:0002474)
0.0 2.0 GO:0070059 intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress(GO:0070059)
0.0 0.4 GO:0090073 positive regulation of protein homodimerization activity(GO:0090073)
0.0 1.5 GO:0031572 G2 DNA damage checkpoint(GO:0031572)
0.0 0.4 GO:0021924 cell proliferation in external granule layer(GO:0021924) cerebellar granule cell precursor proliferation(GO:0021930)
0.0 0.3 GO:0035331 negative regulation of hippo signaling(GO:0035331)
0.0 0.5 GO:0007190 activation of adenylate cyclase activity(GO:0007190)
0.0 0.2 GO:0060179 male mating behavior(GO:0060179)
0.0 0.5 GO:0021511 spinal cord patterning(GO:0021511)
0.0 0.8 GO:0015985 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.0 0.5 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.0 2.1 GO:0006487 protein N-linked glycosylation(GO:0006487)
0.0 0.3 GO:0051967 negative regulation of synaptic transmission, glutamatergic(GO:0051967)
0.0 2.4 GO:0016525 negative regulation of angiogenesis(GO:0016525)
0.0 0.3 GO:2000582 regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)
0.0 0.2 GO:0070365 hepatocyte differentiation(GO:0070365)
0.0 0.2 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.0 0.2 GO:0061113 pancreas morphogenesis(GO:0061113)
0.0 0.1 GO:0071442 regulation of histone H3-K14 acetylation(GO:0071440) positive regulation of histone H3-K14 acetylation(GO:0071442)
0.0 0.2 GO:1901097 negative regulation of autophagosome maturation(GO:1901097)
0.0 0.4 GO:0042347 negative regulation of NF-kappaB import into nucleus(GO:0042347)
0.0 0.3 GO:0051481 negative regulation of cytosolic calcium ion concentration(GO:0051481)
0.0 0.4 GO:0050650 chondroitin sulfate proteoglycan biosynthetic process(GO:0050650)
0.0 0.4 GO:0044458 motile cilium assembly(GO:0044458)
0.0 0.2 GO:0035269 protein O-linked mannosylation(GO:0035269)
0.0 0.8 GO:0006890 retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)
0.0 0.2 GO:0045176 apical protein localization(GO:0045176)
0.0 0.8 GO:0035176 social behavior(GO:0035176) intraspecies interaction between organisms(GO:0051703)
0.0 0.7 GO:1901385 regulation of voltage-gated calcium channel activity(GO:1901385)
0.0 0.2 GO:0042711 maternal behavior(GO:0042711)
0.0 0.4 GO:0022038 corpus callosum development(GO:0022038)
0.0 0.8 GO:0061512 protein localization to cilium(GO:0061512)
0.0 0.7 GO:0061099 negative regulation of protein tyrosine kinase activity(GO:0061099)
0.0 0.3 GO:0042415 norepinephrine metabolic process(GO:0042415)
0.0 0.2 GO:0036120 cellular response to platelet-derived growth factor stimulus(GO:0036120)
0.0 0.5 GO:2000179 positive regulation of neural precursor cell proliferation(GO:2000179)
0.0 0.8 GO:0033120 positive regulation of RNA splicing(GO:0033120)
0.0 0.1 GO:0090557 establishment of endothelial intestinal barrier(GO:0090557)
0.0 0.3 GO:0031116 positive regulation of microtubule polymerization(GO:0031116)
0.0 0.1 GO:0002681 somatic diversification of T cell receptor genes(GO:0002568) somatic recombination of T cell receptor gene segments(GO:0002681) T cell receptor V(D)J recombination(GO:0033153)
0.0 0.4 GO:0035024 negative regulation of Rho protein signal transduction(GO:0035024)
0.0 0.3 GO:0030513 positive regulation of BMP signaling pathway(GO:0030513)
0.0 0.7 GO:2000134 negative regulation of G1/S transition of mitotic cell cycle(GO:2000134)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.9 GO:1990630 IRE1-RACK1-PP2A complex(GO:1990630)
0.2 3.6 GO:0043020 NADPH oxidase complex(GO:0043020)
0.2 0.8 GO:0017177 glucosidase II complex(GO:0017177)
0.2 0.8 GO:1902937 inward rectifier potassium channel complex(GO:1902937)
0.1 0.6 GO:0016533 cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
0.1 1.5 GO:0045179 apical cortex(GO:0045179)
0.1 0.4 GO:1990730 VCP-NSFL1C complex(GO:1990730)
0.1 2.2 GO:0016342 catenin complex(GO:0016342)
0.1 0.6 GO:0070032 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032)
0.1 3.0 GO:0005782 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.1 0.3 GO:1990257 piccolo-bassoon transport vesicle(GO:1990257)
0.1 1.3 GO:0042612 MHC class I protein complex(GO:0042612)
0.1 0.3 GO:0060187 cell pole(GO:0060187)
0.1 0.8 GO:0045261 mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275) proton-transporting ATP synthase complex, catalytic core F(1)(GO:0045261)
0.1 1.4 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.1 3.8 GO:0035371 microtubule plus-end(GO:0035371)
0.1 0.6 GO:0042406 extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.1 0.2 GO:0071595 Nem1-Spo7 phosphatase complex(GO:0071595)
0.1 0.5 GO:0042765 GPI-anchor transamidase complex(GO:0042765)
0.1 2.4 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.1 0.5 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)
0.1 0.2 GO:0005967 mitochondrial pyruvate dehydrogenase complex(GO:0005967)
0.1 1.5 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.1 0.7 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.1 0.8 GO:0016600 flotillin complex(GO:0016600)
0.1 0.7 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
0.1 0.9 GO:1990635 proximal dendrite(GO:1990635)
0.1 1.4 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.0 3.1 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 2.1 GO:0045334 clathrin-coated endocytic vesicle(GO:0045334)
0.0 1.1 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.0 0.6 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.0 0.2 GO:0000125 PCAF complex(GO:0000125)
0.0 1.7 GO:0000407 pre-autophagosomal structure(GO:0000407)
0.0 3.0 GO:0005793 endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)
0.0 0.2 GO:0005883 neurofilament(GO:0005883)
0.0 0.3 GO:0089717 spanning component of plasma membrane(GO:0044214) spanning component of membrane(GO:0089717)
0.0 0.3 GO:0001940 male pronucleus(GO:0001940)
0.0 0.4 GO:0030914 STAGA complex(GO:0030914)
0.0 0.6 GO:0030285 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.0 1.4 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 1.2 GO:0060170 ciliary membrane(GO:0060170)
0.0 1.6 GO:0034707 chloride channel complex(GO:0034707)
0.0 0.4 GO:0031229 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229)
0.0 0.1 GO:0000124 SAGA complex(GO:0000124)
0.0 2.4 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.0 3.4 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)
0.0 1.4 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 0.6 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.0 0.8 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.0 1.2 GO:0009925 basal plasma membrane(GO:0009925)
0.0 3.8 GO:0000139 Golgi membrane(GO:0000139)
0.0 2.4 GO:0005923 bicellular tight junction(GO:0005923)
0.0 0.4 GO:0055038 recycling endosome membrane(GO:0055038)
0.0 0.5 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.0 1.2 GO:0031526 brush border membrane(GO:0031526)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.6 4.8 GO:0016034 maleylacetoacetate isomerase activity(GO:0016034)
0.9 2.7 GO:0051765 inositol tetrakisphosphate kinase activity(GO:0051765)
0.8 8.2 GO:0004886 9-cis retinoic acid receptor activity(GO:0004886)
0.4 1.6 GO:0061628 H3K27me3 modified histone binding(GO:0061628)
0.3 3.0 GO:0005324 long-chain fatty acid transporter activity(GO:0005324)
0.3 6.0 GO:0048406 nerve growth factor binding(GO:0048406)
0.3 3.6 GO:0016174 NAD(P)H oxidase activity(GO:0016174)
0.3 1.2 GO:0036132 13-prostaglandin reductase activity(GO:0036132) 15-oxoprostaglandin 13-oxidase activity(GO:0047522)
0.3 0.9 GO:0070279 vitamin B6 binding(GO:0070279)
0.2 1.7 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.2 0.7 GO:0005333 norepinephrine transmembrane transporter activity(GO:0005333)
0.2 0.8 GO:0072591 citrate-L-glutamate ligase activity(GO:0072591)
0.2 0.8 GO:0043532 angiostatin binding(GO:0043532)
0.2 1.2 GO:0015018 galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018)
0.2 0.8 GO:0030144 alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity(GO:0030144)
0.2 0.6 GO:0050508 glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.2 2.9 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.2 3.8 GO:0050321 tau-protein kinase activity(GO:0050321)
0.2 1.2 GO:0015198 oligopeptide transporter activity(GO:0015198)
0.2 1.2 GO:0004991 parathyroid hormone receptor activity(GO:0004991)
0.2 1.2 GO:0030160 GKAP/Homer scaffold activity(GO:0030160)
0.2 1.0 GO:0000155 phosphorelay sensor kinase activity(GO:0000155)
0.2 0.6 GO:0034739 histone deacetylase activity (H4-K16 specific)(GO:0034739)
0.1 0.4 GO:0005308 creatine transmembrane transporter activity(GO:0005308)
0.1 0.6 GO:0016899 oxidoreductase activity, acting on the CH-OH group of donors, oxygen as acceptor(GO:0016899)
0.1 1.4 GO:0008420 CTD phosphatase activity(GO:0008420)
0.1 1.0 GO:0047288 monosialoganglioside sialyltransferase activity(GO:0047288)
0.1 1.1 GO:0005534 galactose binding(GO:0005534)
0.1 0.5 GO:0008332 low voltage-gated calcium channel activity(GO:0008332)
0.1 1.5 GO:0004016 adenylate cyclase activity(GO:0004016)
0.1 0.4 GO:0004103 choline kinase activity(GO:0004103)
0.1 1.3 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.1 2.1 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.1 0.4 GO:0004699 calcium-independent protein kinase C activity(GO:0004699) ethanol binding(GO:0035276)
0.1 0.5 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.1 1.1 GO:0045294 alpha-catenin binding(GO:0045294)
0.1 1.8 GO:0070411 I-SMAD binding(GO:0070411)
0.1 1.3 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.1 1.0 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.1 1.8 GO:0005537 mannose binding(GO:0005537)
0.1 1.3 GO:0030881 beta-2-microglobulin binding(GO:0030881)
0.1 1.4 GO:0015037 peptide disulfide oxidoreductase activity(GO:0015037)
0.1 0.5 GO:0003923 GPI-anchor transamidase activity(GO:0003923)
0.1 0.3 GO:0045503 dynein light chain binding(GO:0045503)
0.1 1.5 GO:0004697 protein kinase C activity(GO:0004697)
0.1 0.8 GO:0090599 alpha-glucosidase activity(GO:0090599)
0.1 0.5 GO:0097016 L27 domain binding(GO:0097016)
0.1 0.7 GO:0030550 acetylcholine receptor inhibitor activity(GO:0030550)
0.1 0.2 GO:0015275 stretch-activated, cation-selective, calcium channel activity(GO:0015275)
0.1 0.6 GO:0015386 potassium:proton antiporter activity(GO:0015386)
0.1 0.7 GO:0004576 oligosaccharyl transferase activity(GO:0004576) dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.1 3.7 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
0.1 0.7 GO:0061133 endopeptidase activator activity(GO:0061133)
0.1 2.8 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.1 0.6 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.1 0.2 GO:0030297 transmembrane receptor protein tyrosine kinase activator activity(GO:0030297)
0.0 0.3 GO:0043533 inositol 1,3,4,5 tetrakisphosphate binding(GO:0043533)
0.0 0.3 GO:0070579 methylcytosine dioxygenase activity(GO:0070579)
0.0 0.4 GO:0005042 netrin receptor activity(GO:0005042)
0.0 0.2 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.0 0.3 GO:0004013 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.0 1.2 GO:0005161 platelet-derived growth factor receptor binding(GO:0005161)
0.0 0.5 GO:0051378 serotonin binding(GO:0051378)
0.0 1.2 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.0 0.2 GO:0008269 JAK pathway signal transduction adaptor activity(GO:0008269)
0.0 0.6 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
0.0 0.8 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.0 0.9 GO:0045499 chemorepellent activity(GO:0045499)
0.0 0.2 GO:1902379 chemoattractant activity involved in axon guidance(GO:1902379)
0.0 2.7 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.0 1.4 GO:0003899 DNA-directed RNA polymerase activity(GO:0003899)
0.0 0.2 GO:0032184 SUMO polymer binding(GO:0032184)
0.0 2.2 GO:0004879 RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding(GO:0004879) transcription factor activity, direct ligand regulated sequence-specific DNA binding(GO:0098531)
0.0 1.6 GO:0050699 WW domain binding(GO:0050699)
0.0 0.8 GO:0005234 extracellular-glutamate-gated ion channel activity(GO:0005234)
0.0 1.9 GO:0001784 phosphotyrosine binding(GO:0001784)
0.0 1.2 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.0 0.3 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.0 7.0 GO:0061630 ubiquitin protein ligase activity(GO:0061630)
0.0 0.2 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.0 0.8 GO:0000983 transcription factor activity, RNA polymerase II core promoter sequence-specific(GO:0000983)
0.0 0.6 GO:0015248 sterol transporter activity(GO:0015248)
0.0 0.6 GO:0015215 nucleotide transmembrane transporter activity(GO:0015215)
0.0 0.4 GO:0070628 proteasome binding(GO:0070628)
0.0 0.6 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 0.2 GO:0015377 cation:chloride symporter activity(GO:0015377)
0.0 2.3 GO:0005249 voltage-gated potassium channel activity(GO:0005249)
0.0 0.3 GO:0005314 high-affinity glutamate transmembrane transporter activity(GO:0005314)
0.0 0.4 GO:0050811 GABA receptor binding(GO:0050811)
0.0 0.4 GO:0032183 SUMO binding(GO:0032183)
0.0 0.8 GO:0035255 ionotropic glutamate receptor binding(GO:0035255)
0.0 0.2 GO:0015643 toxic substance binding(GO:0015643)
0.0 1.9 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979)
0.0 0.4 GO:0003707 steroid hormone receptor activity(GO:0003707)
0.0 0.3 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.0 0.8 GO:0043531 ADP binding(GO:0043531)
0.0 1.3 GO:0031490 chromatin DNA binding(GO:0031490)
0.0 2.3 GO:0003774 motor activity(GO:0003774)
0.0 0.1 GO:0071253 connexin binding(GO:0071253)
0.0 0.7 GO:0030145 manganese ion binding(GO:0030145)
0.0 1.3 GO:0051087 chaperone binding(GO:0051087)
0.0 0.2 GO:0015026 coreceptor activity(GO:0015026)
0.0 0.4 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 1.5 GO:0019955 cytokine binding(GO:0019955)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 6.4 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.1 1.9 PID LPA4 PATHWAY LPA4-mediated signaling events
0.1 4.6 PID LKB1 PATHWAY LKB1 signaling events
0.0 0.8 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 1.4 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 2.3 PID NCADHERIN PATHWAY N-cadherin signaling events
0.0 1.7 PID NEPHRIN NEPH1 PATHWAY Nephrin/Neph1 signaling in the kidney podocyte
0.0 1.1 PID BETA CATENIN DEG PATHWAY Degradation of beta catenin
0.0 0.9 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.0 2.5 PID PTP1B PATHWAY Signaling events mediated by PTP1B
0.0 0.7 PID ALK1 PATHWAY ALK1 signaling events
0.0 0.6 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.0 1.1 PID RET PATHWAY Signaling events regulated by Ret tyrosine kinase
0.0 0.3 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 1.3 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 1.2 PID BMP PATHWAY BMP receptor signaling
0.0 5.8 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 0.5 PID WNT NONCANONICAL PATHWAY Noncanonical Wnt signaling pathway
0.0 0.8 SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES Genes related to the insulin receptor pathway
0.0 0.5 PID P53 REGULATION PATHWAY p53 pathway
0.0 0.7 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.0 0.6 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.0 0.8 PID HEDGEHOG GLI PATHWAY Hedgehog signaling events mediated by Gli proteins

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 5.7 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.1 3.0 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.1 4.6 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.1 2.1 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.1 1.2 REACTOME TRANSPORT OF ORGANIC ANIONS Genes involved in Transport of organic anions
0.1 1.2 REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
0.1 2.7 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.1 1.5 REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY Genes involved in Adenylate cyclase activating pathway
0.1 1.4 REACTOME VIRAL MESSENGER RNA SYNTHESIS Genes involved in Viral Messenger RNA Synthesis
0.1 6.4 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.1 0.9 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.1 0.5 REACTOME SEROTONIN RECEPTORS Genes involved in Serotonin receptors
0.1 3.3 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.0 0.8 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.0 0.7 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.0 1.2 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.0 0.3 REACTOME RETROGRADE NEUROTROPHIN SIGNALLING Genes involved in Retrograde neurotrophin signalling
0.0 2.0 REACTOME TRAFFICKING OF AMPA RECEPTORS Genes involved in Trafficking of AMPA receptors
0.0 0.8 REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.0 1.2 REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
0.0 2.4 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 0.6 REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB Genes involved in PKA-mediated phosphorylation of CREB
0.0 1.5 REACTOME GPVI MEDIATED ACTIVATION CASCADE Genes involved in GPVI-mediated activation cascade
0.0 1.7 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.0 0.7 REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 3 PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter
0.0 0.4 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.0 0.8 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.0 2.3 REACTOME UNFOLDED PROTEIN RESPONSE Genes involved in Unfolded Protein Response
0.0 0.3 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.0 0.4 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.0 0.4 REACTOME DAG AND IP3 SIGNALING Genes involved in DAG and IP3 signaling
0.0 1.4 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.0 0.5 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 0.3 REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
0.0 4.7 REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES Genes involved in Metabolism of amino acids and derivatives
0.0 0.5 REACTOME REGULATION OF KIT SIGNALING Genes involved in Regulation of KIT signaling
0.0 0.2 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0 0.6 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.5 REACTOME POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS Genes involved in Post-translational modification: synthesis of GPI-anchored proteins
0.0 0.9 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.0 0.4 REACTOME G ALPHA S SIGNALLING EVENTS Genes involved in G alpha (s) signalling events