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GSE58827: Dynamics of the Mouse Liver

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Results for Mecom

Z-value: 0.75

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Transcription factors associated with Mecom

Gene Symbol Gene ID Gene Info
Mecom
ENSMUSG00000027684.17 MDS1 and EVI1 complex locus

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Mecommm39_v1_chr3_-_30563919_30563971-0.591.5e-04Click!

Activity profile of Mecom motif

Sorted Z-values of Mecom motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr4_-_62005498 21.13 ENSMUST00000107488.4
ENSMUST00000107472.8
ENSMUST00000084531.11
Mup3
major urinary protein 3
chr4_-_61259801 19.89 ENSMUST00000125461.8
Mup14
major urinary protein 14
chr6_+_138117295 7.48 ENSMUST00000008684.11
Mgst1
microsomal glutathione S-transferase 1
chr1_+_152275575 4.31 ENSMUST00000044311.9
Colgalt2
collagen beta(1-O)galactosyltransferase 2
chr7_+_140415170 2.48 ENSMUST00000211372.2
ENSMUST00000026554.11
ENSMUST00000185612.3
Urah
urate (5-hydroxyiso-) hydrolase
chr7_+_140415431 2.24 ENSMUST00000209978.2
ENSMUST00000210916.2
Urah
urate (5-hydroxyiso-) hydrolase
chr4_+_132766793 2.18 ENSMUST00000105914.2
Ahdc1
AT hook, DNA binding motif, containing 1
chr4_+_60003438 1.90 ENSMUST00000107517.8
ENSMUST00000107520.2
Mup6
major urinary protein 6
chrX_+_21581135 1.69 ENSMUST00000033414.8
Slc6a14
solute carrier family 6 (neurotransmitter transporter), member 14
chr10_+_61484331 1.49 ENSMUST00000020286.7
Ppa1
pyrophosphatase (inorganic) 1
chr2_+_34764408 1.42 ENSMUST00000113068.9
ENSMUST00000047447.13
Cutal
cutA divalent cation tolerance homolog-like
chr5_+_66417233 1.38 ENSMUST00000202994.4
ENSMUST00000201100.4
Nsun7
NOL1/NOP2/Sun domain family, member 7
chr6_-_34887743 1.36 ENSMUST00000081214.12
Wdr91
WD repeat domain 91
chr1_+_34275665 1.32 ENSMUST00000194192.3
Dst
dystonin
chr9_-_104214920 1.17 ENSMUST00000062723.14
ENSMUST00000215852.2
Acpp
acid phosphatase, prostate
chr5_-_136003294 1.15 ENSMUST00000154181.2
ENSMUST00000111152.8
ENSMUST00000111153.8
Ssc4d
scavenger receptor cysteine rich family, 4 domains
chr2_+_34764496 1.14 ENSMUST00000028228.6
Cutal
cutA divalent cation tolerance homolog-like
chr15_-_96947963 1.11 ENSMUST00000230907.2
Slc38a4
solute carrier family 38, member 4
chr17_-_32639936 1.03 ENSMUST00000170392.9
ENSMUST00000237165.2
ENSMUST00000235892.2
ENSMUST00000114455.3
Pglyrp2
peptidoglycan recognition protein 2
chr10_-_68114543 0.93 ENSMUST00000219238.2
Arid5b
AT rich interactive domain 5B (MRF1-like)
chr11_-_68277799 0.92 ENSMUST00000135141.2
Ntn1
netrin 1
chr8_+_46944000 0.87 ENSMUST00000110372.9
ENSMUST00000130563.2
Acsl1
acyl-CoA synthetase long-chain family member 1
chr6_-_145156517 0.85 ENSMUST00000111728.8
ENSMUST00000204105.2
ENSMUST00000060797.10
Casc1
cancer susceptibility candidate 1
chr11_-_115258493 0.83 ENSMUST00000123428.2
Hid1
HID1 domain containing
chrX_-_88453295 0.81 ENSMUST00000113959.8
ENSMUST00000113960.3
Dcaf8l
DDB1 and CUL4 associated factor 8 like
chrX_+_149981074 0.81 ENSMUST00000184730.8
ENSMUST00000184392.8
ENSMUST00000096285.5
Wnk3
WNK lysine deficient protein kinase 3
chr14_-_56448874 0.78 ENSMUST00000022757.5
Gzmf
granzyme F
chr16_-_48592319 0.78 ENSMUST00000239408.2
Trat1
T cell receptor associated transmembrane adaptor 1
chr1_-_189075515 0.76 ENSMUST00000193319.6
Kcnk2
potassium channel, subfamily K, member 2
chr8_-_73188887 0.73 ENSMUST00000109974.2
Calr3
calreticulin 3
chr11_-_69553390 0.66 ENSMUST00000129224.8
ENSMUST00000155200.8
Mpdu1
mannose-P-dolichol utilization defect 1
chr16_-_48592372 0.65 ENSMUST00000231701.3
Trat1
T cell receptor associated transmembrane adaptor 1
chr9_-_104214899 0.64 ENSMUST00000112590.3
Acpp
acid phosphatase, prostate
chr11_-_69553451 0.63 ENSMUST00000018905.12
Mpdu1
mannose-P-dolichol utilization defect 1
chr10_-_27492792 0.62 ENSMUST00000189575.2
Lama2
laminin, alpha 2
chr2_-_45000250 0.62 ENSMUST00000201211.4
ENSMUST00000177302.8
Zeb2
zinc finger E-box binding homeobox 2
chr6_-_30680502 0.62 ENSMUST00000133373.8
Cep41
centrosomal protein 41
chr9_-_44437801 0.61 ENSMUST00000215661.2
Cxcr5
chemokine (C-X-C motif) receptor 5
chr13_+_19362068 0.61 ENSMUST00000103553.3
Trgv7
T cell receptor gamma, variable 7
chr8_+_108669276 0.60 ENSMUST00000220518.2
Zfhx3
zinc finger homeobox 3
chr5_-_120605361 0.57 ENSMUST00000132916.2
Sdsl
serine dehydratase-like
chr1_+_119934624 0.56 ENSMUST00000072886.11
ENSMUST00000189037.2
Sctr
secretin receptor
chr5_+_34683141 0.55 ENSMUST00000125817.8
ENSMUST00000067638.14
Sh3bp2
SH3-domain binding protein 2
chr9_+_59496571 0.54 ENSMUST00000121266.8
ENSMUST00000118164.3
Celf6
CUGBP, Elav-like family member 6
chr18_+_84738996 0.54 ENSMUST00000235504.2
Dipk1c
divergent protein kinase domain 1C
chr10_+_63293284 0.52 ENSMUST00000105440.8
Ctnna3
catenin (cadherin associated protein), alpha 3
chr3_+_99161070 0.51 ENSMUST00000029462.10
Tbx15
T-box 15
chr15_-_36140539 0.46 ENSMUST00000172831.8
Rgs22
regulator of G-protein signalling 22
chr6_-_72343935 0.45 ENSMUST00000154098.3
Rnf181
ring finger protein 181
chr10_+_3690348 0.44 ENSMUST00000120274.8
Plekhg1
pleckstrin homology domain containing, family G (with RhoGef domain) member 1
chrX_+_11175063 0.44 ENSMUST00000178595.2
H2al1d
H2A histone family member L1D
chrX_-_112095181 0.44 ENSMUST00000026607.15
ENSMUST00000113388.3
Chm
choroidermia (RAB escort protein 1)
chr3_-_144511566 0.43 ENSMUST00000199029.2
Clca3a2
chloride channel accessory 3A2
chr17_+_93506590 0.42 ENSMUST00000064775.8
Adcyap1
adenylate cyclase activating polypeptide 1
chr2_+_97298002 0.42 ENSMUST00000059049.8
Lrrc4c
leucine rich repeat containing 4C
chr5_-_106606032 0.39 ENSMUST00000086795.8
Barhl2
BarH like homeobox 2
chr1_-_162812087 0.39 ENSMUST00000028010.9
Fmo3
flavin containing monooxygenase 3
chr9_-_35523237 0.37 ENSMUST00000034610.4
Pate4
prostate and testis expressed 4
chr5_+_65288418 0.36 ENSMUST00000101191.10
ENSMUST00000204348.3
Klhl5
kelch-like 5
chr17_+_93506435 0.36 ENSMUST00000234646.2
ENSMUST00000234081.2
Adcyap1
adenylate cyclase activating polypeptide 1
chr19_+_55886708 0.35 ENSMUST00000148666.3
Tcf7l2
transcription factor 7 like 2, T cell specific, HMG box
chrX_+_11187731 0.35 ENSMUST00000177926.3
H2al1h
H2A histone family member L1H
chr13_-_21476849 0.35 ENSMUST00000110491.9
Gpx5
glutathione peroxidase 5
chr11_-_82910912 0.35 ENSMUST00000130822.3
Slfn8
schlafen 8
chr8_-_43760017 0.34 ENSMUST00000082120.5
Zfp42
zinc finger protein 42
chr4_+_65042411 0.33 ENSMUST00000084501.4
Pappa
pregnancy-associated plasma protein A
chr11_+_42312150 0.32 ENSMUST00000192403.2
Gabrb2
gamma-aminobutyric acid (GABA) A receptor, subunit beta 2
chr14_-_51311892 0.32 ENSMUST00000216202.2
Olfr750
olfactory receptor 750
chr9_+_72714156 0.31 ENSMUST00000055535.9
Prtg
protogenin
chrX_+_11178173 0.31 ENSMUST00000178979.2
H2al1e
H2A histone family member L1E
chr11_-_82911548 0.30 ENSMUST00000108152.9
Slfn8
schlafen 8
chrX_+_11181397 0.30 ENSMUST00000179004.2
H2al1f
H2A histone family member L1F
chrX_+_11190898 0.30 ENSMUST00000164729.3
H2al1i
H2A histone family member L1I
chrX_+_11165496 0.27 ENSMUST00000188439.2
H2al1a
H2A histone family member L1A
chr17_-_37409147 0.27 ENSMUST00000216376.2
ENSMUST00000217372.2
Olfr91
olfactory receptor 91
chrX_+_111513971 0.26 ENSMUST00000071814.13
Zfp711
zinc finger protein 711
chr4_+_40920047 0.26 ENSMUST00000030122.5
Spink4
serine peptidase inhibitor, Kazal type 4
chr11_-_50844572 0.26 ENSMUST00000162420.2
ENSMUST00000051159.3
Prop1
paired like homeodomain factor 1
chr10_-_129948657 0.26 ENSMUST00000081469.2
Olfr823
olfactory receptor 823
chr13_+_83672654 0.26 ENSMUST00000199019.5
Mef2c
myocyte enhancer factor 2C
chr17_-_37613523 0.25 ENSMUST00000215392.2
Olfr101
olfactory receptor 101
chr6_+_24748324 0.25 ENSMUST00000031691.3
Hyal4
hyaluronoglucosaminidase 4
chr6_+_113369377 0.25 ENSMUST00000032414.11
ENSMUST00000038889.12
Ttll3
tubulin tyrosine ligase-like family, member 3
chr3_+_41697046 0.24 ENSMUST00000120167.8
ENSMUST00000108065.9
ENSMUST00000146165.8
ENSMUST00000192193.6
ENSMUST00000119572.8
ENSMUST00000026867.14
ENSMUST00000026868.13
D3Ertd751e
DNA segment, Chr 3, ERATO Doi 751, expressed
chr17_+_33651864 0.23 ENSMUST00000174088.3
Actl9
actin-like 9
chr7_-_102241093 0.23 ENSMUST00000213540.3
Olfr551
olfactory receptor 551
chr11_-_82911615 0.23 ENSMUST00000038141.15
ENSMUST00000092838.11
Slfn8
schlafen 8
chr16_-_57575070 0.22 ENSMUST00000089332.5
Col8a1
collagen, type VIII, alpha 1
chr14_+_87654045 0.22 ENSMUST00000169504.8
ENSMUST00000168275.9
ENSMUST00000170865.8
Tdrd3
tudor domain containing 3
chr11_-_59937302 0.22 ENSMUST00000000310.14
ENSMUST00000102693.9
ENSMUST00000148512.2
Pemt
phosphatidylethanolamine N-methyltransferase
chr13_-_58423461 0.22 ENSMUST00000223811.2
Gkap1
G kinase anchoring protein 1
chr7_+_6225277 0.21 ENSMUST00000072662.12
ENSMUST00000155314.2
Zscan5b
zinc finger and SCAN domain containing 5B
chr12_-_11258973 0.20 ENSMUST00000049877.3
Msgn1
mesogenin 1
chr17_-_33440626 0.20 ENSMUST00000213751.2
ENSMUST00000213642.2
ENSMUST00000215450.2
ENSMUST00000208645.3
Olfr1564
olfactory receptor 1564
chrX_+_11184495 0.17 ENSMUST00000179859.2
H2al1g
H2A histone family member L1G
chr17_-_37430949 0.15 ENSMUST00000214994.2
ENSMUST00000216341.2
Olfr92
olfactory receptor 92
chr16_-_29360301 0.14 ENSMUST00000057018.15
ENSMUST00000182627.8
Atp13a4
ATPase type 13A4
chr16_+_94225942 0.12 ENSMUST00000141176.2
Ttc3
tetratricopeptide repeat domain 3
chr3_-_151953894 0.11 ENSMUST00000196529.5
Nexn
nexilin
chr13_-_27697185 0.11 ENSMUST00000018389.5
ENSMUST00000110350.9
Prl8a8
prolactin family 8, subfamily a, member 81
chr9_+_39903409 0.11 ENSMUST00000217600.2
Olfr978
olfactory receptor 978
chr2_-_125602234 0.10 ENSMUST00000139944.2
Secisbp2l
SECIS binding protein 2-like
chrX_+_47712676 0.09 ENSMUST00000177710.2
Slc25a14
solute carrier family 25 (mitochondrial carrier, brain), member 14
chr11_-_65636651 0.09 ENSMUST00000138093.2
Map2k4
mitogen-activated protein kinase kinase 4
chr12_-_35584968 0.09 ENSMUST00000116436.9
Ahr
aryl-hydrocarbon receptor
chr15_-_48655329 0.09 ENSMUST00000160658.8
ENSMUST00000100670.10
ENSMUST00000162830.8
Csmd3
CUB and Sushi multiple domains 3
chr9_-_44437694 0.09 ENSMUST00000062215.8
Cxcr5
chemokine (C-X-C motif) receptor 5
chr3_-_123029745 0.09 ENSMUST00000106426.8
Synpo2
synaptopodin 2
chrX_+_11171894 0.09 ENSMUST00000178806.2
H2al1c
H2A histone family member L1C
chr14_+_46616871 0.08 ENSMUST00000141358.2
Gm15217
predicted gene 15217
chr3_-_123029782 0.08 ENSMUST00000106427.8
ENSMUST00000198584.2
Synpo2
synaptopodin 2
chr2_-_90301592 0.08 ENSMUST00000111493.8
Ptprj
protein tyrosine phosphatase, receptor type, J
chrX_-_153911405 0.08 ENSMUST00000076671.4
Cldn34b2
claudin 34B2
chr19_-_37153436 0.07 ENSMUST00000142973.2
ENSMUST00000154376.8
Cpeb3
cytoplasmic polyadenylation element binding protein 3
chr6_+_65502344 0.06 ENSMUST00000212375.2
Tnip3
TNFAIP3 interacting protein 3
chrX_+_9216866 0.06 ENSMUST00000178196.3
H2al1k
H2A histone family member L1K
chr5_-_151529486 0.05 ENSMUST00000233599.2
ENSMUST00000232905.2
Vmn2r18
vomeronasal 2, receptor 18
chr6_+_96090127 0.05 ENSMUST00000122120.8
Tafa1
TAFA chemokine like family member 1
chr4_-_110149916 0.04 ENSMUST00000106601.8
Elavl4
ELAV like RNA binding protein 4
chr13_-_58422647 0.04 ENSMUST00000225034.2
Gkap1
G kinase anchoring protein 1
chrX_+_11168671 0.03 ENSMUST00000189531.2
H2al1b
H2A histone family member L1B
chr9_+_38725910 0.03 ENSMUST00000213164.2
Olfr922
olfactory receptor 922
chr14_+_34097422 0.03 ENSMUST00000111908.3
Mmrn2
multimerin 2
chr10_-_107555840 0.02 ENSMUST00000050702.9
Ptprq
protein tyrosine phosphatase, receptor type, Q
chr9_-_102496047 0.02 ENSMUST00000215253.2
Cep63
centrosomal protein 63
chr2_+_109522781 0.02 ENSMUST00000111050.10
Bdnf
brain derived neurotrophic factor
chr6_+_65502292 0.00 ENSMUST00000212402.2
Tnip3
TNFAIP3 interacting protein 3

Network of associatons between targets according to the STRING database.

First level regulatory network of Mecom

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.9 7.5 GO:0071449 cellular response to lipid hydroperoxide(GO:0071449)
0.6 21.1 GO:0035634 response to stilbenoid(GO:0035634)
0.5 1.8 GO:0042723 thiamine metabolic process(GO:0006772) thiamine-containing compound metabolic process(GO:0042723) positive regulation of adenosine receptor signaling pathway(GO:0060168)
0.3 1.4 GO:0030382 sperm mitochondrion organization(GO:0030382)
0.3 0.8 GO:2000686 regulation of rubidium ion transmembrane transporter activity(GO:2000686)
0.3 0.8 GO:1900039 positive regulation of cellular response to hypoxia(GO:1900039)
0.2 1.4 GO:0001920 negative regulation of receptor recycling(GO:0001920)
0.2 1.0 GO:0032824 peptidoglycan metabolic process(GO:0000270) peptidoglycan catabolic process(GO:0009253) negative regulation of natural killer cell differentiation(GO:0032824) negative regulation of natural killer cell differentiation involved in immune response(GO:0032827)
0.2 0.8 GO:0071651 positive regulation of chemokine (C-C motif) ligand 5 production(GO:0071651)
0.2 4.7 GO:0006144 purine nucleobase metabolic process(GO:0006144)
0.1 0.6 GO:1904059 regulation of locomotor rhythm(GO:1904059)
0.1 0.6 GO:1902748 positive regulation of lens fiber cell differentiation(GO:1902748)
0.1 0.9 GO:0033564 anterior/posterior axon guidance(GO:0033564)
0.1 1.3 GO:0006488 dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.1 0.9 GO:0044539 long-chain fatty acid import(GO:0044539)
0.1 0.9 GO:0060613 fat pad development(GO:0060613)
0.1 0.5 GO:0086073 bundle of His cell-Purkinje myocyte adhesion involved in cell communication(GO:0086073)
0.1 1.3 GO:0008090 retrograde axonal transport(GO:0008090)
0.1 0.3 GO:0060126 hypophysis morphogenesis(GO:0048850) somatotropin secreting cell differentiation(GO:0060126)
0.0 0.4 GO:0018344 protein geranylgeranylation(GO:0018344)
0.0 0.3 GO:2000653 regulation of genetic imprinting(GO:2000653)
0.0 0.5 GO:0032224 positive regulation of synaptic transmission, cholinergic(GO:0032224)
0.0 0.4 GO:0044334 canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition(GO:0044334)
0.0 0.3 GO:0007199 G-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messenger(GO:0007199)
0.0 0.2 GO:0050747 positive regulation of lipoprotein metabolic process(GO:0050747)
0.0 0.1 GO:0002182 cytoplasmic translational elongation(GO:0002182) regulation of cytoplasmic translational elongation(GO:1900247) negative regulation of cytoplasmic translational elongation(GO:1900248)
0.0 0.3 GO:0003138 primary heart field specification(GO:0003138) sinoatrial valve development(GO:0003172) sinoatrial valve morphogenesis(GO:0003185)
0.0 1.1 GO:0003333 amino acid transmembrane transport(GO:0003333)
0.0 2.1 GO:0006342 chromatin silencing(GO:0006342)
0.0 0.2 GO:0006027 glycosaminoglycan catabolic process(GO:0006027)
0.0 0.1 GO:0003241 growth involved in heart morphogenesis(GO:0003241)
0.0 0.7 GO:0048535 lymph node development(GO:0048535)
0.0 0.3 GO:0071420 cellular response to histamine(GO:0071420)
0.0 0.4 GO:0017144 drug metabolic process(GO:0017144)
0.0 0.5 GO:0071625 vocalization behavior(GO:0071625)
0.0 0.2 GO:2000298 regulation of Rho-dependent protein serine/threonine kinase activity(GO:2000298)
0.0 0.1 GO:0006451 selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.3 GO:0031673 H zone(GO:0031673)
0.1 0.5 GO:0070722 Tle3-Aes complex(GO:0070722)
0.1 0.8 GO:0044305 calyx of Held(GO:0044305)
0.1 8.4 GO:0031903 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.1 0.4 GO:0005968 Rab-protein geranylgeranyltransferase complex(GO:0005968)
0.0 1.4 GO:0042101 T cell receptor complex(GO:0042101)
0.0 0.4 GO:0070369 beta-catenin-TCF7L2 complex(GO:0070369)
0.0 1.6 GO:0005771 multivesicular body(GO:0005771)
0.0 0.5 GO:0005916 fascia adherens(GO:0005916)
0.0 4.7 GO:0005777 peroxisome(GO:0005777) microbody(GO:0042579)
0.0 0.4 GO:0097524 sperm plasma membrane(GO:0097524)
0.0 0.1 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
0.0 0.5 GO:0005605 basal lamina(GO:0005605)
0.0 1.9 GO:0031526 brush border membrane(GO:0031526)
0.0 0.3 GO:1902711 GABA-A receptor complex(GO:1902711)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.6 4.7 GO:0033971 hydroxyisourate hydrolase activity(GO:0033971)
0.6 1.8 GO:0052642 lysophosphatidic acid phosphatase activity(GO:0052642)
0.6 1.7 GO:0005275 amine transmembrane transporter activity(GO:0005275)
0.4 1.5 GO:0004427 inorganic diphosphatase activity(GO:0004427)
0.3 7.5 GO:0043295 glutathione binding(GO:0043295) oligopeptide binding(GO:1900750)
0.2 21.1 GO:0005550 pheromone binding(GO:0005550)
0.2 0.6 GO:0004794 L-threonine ammonia-lyase activity(GO:0004794)
0.2 0.9 GO:0043758 acetate-CoA ligase (ADP-forming) activity(GO:0043758)
0.2 1.0 GO:0016019 N-acetylmuramoyl-L-alanine amidase activity(GO:0008745) peptidoglycan receptor activity(GO:0016019)
0.1 4.3 GO:0035250 UDP-galactosyltransferase activity(GO:0035250)
0.1 0.7 GO:0016494 C-X-C chemokine receptor activity(GO:0016494)
0.1 0.8 GO:0019869 chloride channel inhibitor activity(GO:0019869)
0.0 0.5 GO:0086080 protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
0.0 0.8 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.0 0.3 GO:0005237 inhibitory extracellular ligand-gated ion channel activity(GO:0005237)
0.0 0.4 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.0 2.6 GO:0005507 copper ion binding(GO:0005507)
0.0 0.2 GO:0004415 hyalurononglucosaminidase activity(GO:0004415)
0.0 0.8 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.0 0.2 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.0 0.7 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.0 0.4 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
0.0 0.4 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.0 0.4 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.0 0.3 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.0 0.9 GO:0048487 beta-tubulin binding(GO:0048487)
0.0 0.6 GO:0070412 R-SMAD binding(GO:0070412)
0.0 0.1 GO:0008545 JUN kinase kinase activity(GO:0008545)
0.0 0.4 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.0 0.6 GO:0005044 scavenger receptor activity(GO:0005044)
0.0 0.3 GO:0003680 AT DNA binding(GO:0003680)
0.0 0.5 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.4 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.0 1.3 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 7.5 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.1 1.7 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.1 0.9 REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING Genes involved in Role of second messengers in netrin-1 signaling
0.1 0.8 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.0 1.5 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.0 1.4 REACTOME DOWNSTREAM TCR SIGNALING Genes involved in Downstream TCR signaling
0.0 0.9 REACTOME ALPHA LINOLENIC ACID ALA METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.0 1.1 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.0 0.9 REACTOME GLUCAGON TYPE LIGAND RECEPTORS Genes involved in Glucagon-type ligand receptors
0.0 0.3 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 0.3 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.0 0.5 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions