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GSE58827: Dynamics of the Mouse Liver

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Results for Mef2b

Z-value: 0.69

Motif logo

Transcription factors associated with Mef2b

Gene Symbol Gene ID Gene Info
ENSMUSG00000079033.11 myocyte enhancer factor 2B

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Mef2bmm39_v1_chr8_+_70605404_70605431-0.326.1e-02Click!

Activity profile of Mef2b motif

Sorted Z-values of Mef2b motif

Promoter Log-likelihood Transcript Gene Gene Info
chr19_-_7779943 3.45 ENSMUST00000120522.8
solute carrier family 22 (organic cation transporter), member 26
chr19_-_7780025 3.42 ENSMUST00000065634.8
solute carrier family 22 (organic cation transporter), member 26
chr19_-_40175709 2.09 ENSMUST00000051846.13
cytochrome P450, family 2, subfamily c, polypeptide 70
chr3_-_98721750 1.58 ENSMUST00000029463.13
hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 6
chr1_-_66974492 1.39 ENSMUST00000120415.8
ENSMUST00000119429.8
myosin, light polypeptide 1
chr3_-_122828592 1.29 ENSMUST00000029761.14
myozenin 2
chr1_-_66974694 1.28 ENSMUST00000186202.7
myosin, light polypeptide 1
chr3_+_89366425 1.22 ENSMUST00000029564.12
phosphomevalonate kinase
chr5_+_120614587 1.21 ENSMUST00000201684.4
ENSMUST00000066540.14
serine dehydratase
chr7_+_141995545 1.11 ENSMUST00000105971.8
ENSMUST00000145287.8
troponin I, skeletal, fast 2
chr3_+_89366632 1.08 ENSMUST00000107410.8
phosphomevalonate kinase
chr7_+_141996067 1.07 ENSMUST00000149529.8
troponin I, skeletal, fast 2
chr10_-_88440869 1.01 ENSMUST00000119185.8
ENSMUST00000238199.2
myosin binding protein C, slow-type
chr7_-_48497771 1.00 ENSMUST00000032658.14
cysteine and glycine-rich protein 3
chr14_-_20706556 0.98 ENSMUST00000090469.8
myozenin 1
chr9_+_121606750 0.90 ENSMUST00000098272.4
kelch-like 40
chr10_+_87694117 0.80 ENSMUST00000122386.8
insulin-like growth factor 1
chr7_+_127603083 0.78 ENSMUST00000106248.8
tripartite motif-containing 72
chrX_+_156481906 0.78 ENSMUST00000136141.2
ENSMUST00000190091.7
small muscle protein, X-linked
chr15_+_25940912 0.78 ENSMUST00000226438.2
reticulophagy regulator 1
chr2_+_69500444 0.78 ENSMUST00000100050.4
kelch-like 41
chr3_+_101993787 0.77 ENSMUST00000165540.9
ENSMUST00000164123.2
calsequestrin 2
chr11_+_67689094 0.77 ENSMUST00000168612.8
dehydrogenase/reductase (SDR family) member 7C
chr3_+_101993731 0.76 ENSMUST00000029454.12
calsequestrin 2
chr7_+_44984681 0.75 ENSMUST00000085351.7
histidine rich calcium binding protein
chr11_+_70548022 0.73 ENSMUST00000157027.8
ENSMUST00000072841.12
ENSMUST00000108548.8
ENSMUST00000126241.8
enolase 3, beta muscle
chr15_+_25940781 0.72 ENSMUST00000227275.2
reticulophagy regulator 1
chr8_+_15107646 0.71 ENSMUST00000033842.4
myomesin 2
chr1_-_172047282 0.70 ENSMUST00000170700.2
ENSMUST00000003554.11
calsequestrin 1
chr5_+_122239007 0.69 ENSMUST00000014080.13
ENSMUST00000111750.8
myosin, light polypeptide 2, regulatory, cardiac, slow
chr5_+_122239030 0.68 ENSMUST00000139213.8
ENSMUST00000111751.8
ENSMUST00000155612.8
myosin, light polypeptide 2, regulatory, cardiac, slow
chr17_-_45903494 0.66 ENSMUST00000163492.8
solute carrier family 29 (nucleoside transporters), member 1
chr5_-_116560916 0.66 ENSMUST00000036991.5
heat shock protein 8
chr7_-_127805518 0.64 ENSMUST00000033049.9
cytochrome c oxidase subunit 6A2
chr2_-_6217844 0.62 ENSMUST00000042658.5
enoyl Coenzyme A hydratase domain containing 3
chr4_-_134099840 0.61 ENSMUST00000030643.3
exostosin-like glycosyltransferase 1
chr7_+_80707328 0.61 ENSMUST00000107348.2
alpha-kinase 3
chr11_-_94867153 0.60 ENSMUST00000103162.8
ENSMUST00000166320.8
sarcoglycan, alpha (dystrophin-associated glycoprotein)
chr16_+_4825216 0.58 ENSMUST00000185147.8
small integral membrane protein 22
chr16_+_4825146 0.57 ENSMUST00000184439.8
small integral membrane protein 22
chr17_-_45903410 0.57 ENSMUST00000166119.8
solute carrier family 29 (nucleoside transporters), member 1
chr17_+_28451674 0.55 ENSMUST00000002320.16
ENSMUST00000232879.2
ENSMUST00000166744.8
peroxisome proliferator activator receptor delta
chr11_+_70548513 0.53 ENSMUST00000134087.8
enolase 3, beta muscle
chr16_+_4825170 0.52 ENSMUST00000178155.9
small integral membrane protein 22
chrX_+_156482116 0.51 ENSMUST00000112521.8
small muscle protein, X-linked
chr8_+_105688344 0.49 ENSMUST00000043183.8
carboxylesterase 2G
chr4_-_73869071 0.49 ENSMUST00000095023.2
ENSMUST00000030101.4
RIKEN cDNA 2310002L09 gene
chr6_+_121277186 0.48 ENSMUST00000064580.14
solute carrier family 6 (neurotransmitter transporter, GABA), member 13
chr17_-_45903188 0.47 ENSMUST00000164769.8
solute carrier family 29 (nucleoside transporters), member 1
chr15_+_25940931 0.46 ENSMUST00000110438.3
reticulophagy regulator 1
chr3_-_86906591 0.45 ENSMUST00000063869.11
ENSMUST00000029717.4
CD1d1 antigen
chr9_-_119852624 0.44 ENSMUST00000111635.4
xin actin-binding repeat containing 1
chrX_-_94521712 0.43 ENSMUST00000033549.3
ankyrin repeat and SOCS box-containing 12
chr4_+_118965992 0.40 ENSMUST00000134105.8
ENSMUST00000144329.8
ENSMUST00000208090.2
solute carrier family 2 (facilitated glucose transporter), member 1
chr1_+_155433858 0.39 ENSMUST00000080138.13
ENSMUST00000035560.9
ENSMUST00000097529.5
acyl-Coenzyme A binding domain containing 6
chr2_-_160169414 0.38 ENSMUST00000099127.3
predicted gene 826
chr4_+_43493344 0.37 ENSMUST00000030181.12
ENSMUST00000107922.3
coiled-coil domain containing 107
chr4_+_118965908 0.36 ENSMUST00000030398.10
solute carrier family 2 (facilitated glucose transporter), member 1
chr5_-_24652775 0.35 ENSMUST00000123167.2
ENSMUST00000030799.15
transmembrane and ubiquitin-like domain containing 1
chr1_-_75195127 0.34 ENSMUST00000079464.13
tubulin, alpha 4A
chr3_-_158267771 0.33 ENSMUST00000199890.5
ENSMUST00000238317.3
ENSMUST00000200137.5
ENSMUST00000106044.6
leucine rich repeat containing 7
chr17_+_12597490 0.33 ENSMUST00000014578.7
plasminogen
chr15_+_25940859 0.33 ENSMUST00000226750.2
reticulophagy regulator 1
chrX_+_163221035 0.33 ENSMUST00000033755.6
ankyrin repeat and SOCS box-containing 11
chr13_+_89687915 0.32 ENSMUST00000022108.9
hyaluronan and proteoglycan link protein 1
chr3_+_32871669 0.32 ENSMUST00000072312.12
ENSMUST00000108228.8
ubiquitin specific peptidase 13 (isopeptidase T-3)
chr11_+_77353431 0.31 ENSMUST00000130255.2
coronin 6
chrX_+_10583629 0.31 ENSMUST00000115524.8
ENSMUST00000008179.7
ENSMUST00000156321.2
Mid1 interacting protein 1 (gastrulation specific G12-like (zebrafish))
chr14_-_52151026 0.31 ENSMUST00000228164.2
N-myc downstream regulated gene 2
chr5_+_115034997 0.31 ENSMUST00000031542.13
ENSMUST00000146072.8
ENSMUST00000150361.2
2'-5' oligoadenylate synthetase-like 2
chr7_-_103492361 0.30 ENSMUST00000063957.6
hemoglobin Z, beta-like embryonic chain
chr18_+_67597929 0.30 ENSMUST00000025411.9
PRELI domain containing 3A
chrX_+_67805497 0.28 ENSMUST00000071848.7
Fmr1 neighbor
chr5_+_115373895 0.28 ENSMUST00000081497.13
processing of precursor 5, ribonuclease P/MRP family (S. cerevisiae)
chr19_-_8700728 0.27 ENSMUST00000170157.8
solute carrier family 3 (activators of dibasic and neutral amino acid transport), member 2
chr11_-_54140462 0.27 ENSMUST00000019060.6
colony stimulating factor 2 (granulocyte-macrophage)
chr10_-_128384971 0.27 ENSMUST00000176906.2
ribosomal protein L41
chr10_-_128384994 0.27 ENSMUST00000177163.8
ENSMUST00000176683.8
ENSMUST00000176010.8
ribosomal protein L41
chr2_+_136555364 0.26 ENSMUST00000028727.11
ENSMUST00000110098.4
synaptosomal-associated protein 25
chr1_-_190915441 0.26 ENSMUST00000027941.14
activating transcription factor 3
chr5_-_28415020 0.25 ENSMUST00000118882.2
canopy FGF signaling regulator 1
chr9_-_36708599 0.25 ENSMUST00000238932.2
ENSMUST00000115086.13
etoposide induced 2.4 mRNA
chr2_+_90948481 0.25 ENSMUST00000137942.8
ENSMUST00000111430.10
ENSMUST00000169776.2
myosin binding protein C, cardiac
chr10_-_95159410 0.24 ENSMUST00000217809.2
CASP2 and RIPK1 domain containing adaptor with death domain
chr7_+_27878894 0.24 ENSMUST00000085901.13
ENSMUST00000172761.8
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1b
chr8_+_95584078 0.24 ENSMUST00000109521.4
polymerase (RNA) II (DNA directed) polypeptide C
chr9_-_36708569 0.24 ENSMUST00000163192.11
etoposide induced 2.4 mRNA
chr14_-_20718337 0.23 ENSMUST00000057090.12
ENSMUST00000117386.2
synaptopodin 2-like
chr6_-_88604404 0.23 ENSMUST00000120933.5
kelch repeat and BTB (POZ) domain containing 12
chr18_-_35631914 0.23 ENSMUST00000236007.2
ENSMUST00000237896.2
ENSMUST00000235778.2
ENSMUST00000235524.2
ENSMUST00000235691.2
ENSMUST00000235619.2
ENSMUST00000025215.10
endoplasmic reticulum chaperone SIL1 homolog (S. cerevisiae)
chr6_+_121277693 0.23 ENSMUST00000142419.2
solute carrier family 6 (neurotransmitter transporter, GABA), member 13
chr15_+_98065039 0.23 ENSMUST00000031914.6
coiled-coil domain containing 184
chr18_-_25887173 0.22 ENSMUST00000225477.2
CUGBP, Elav-like family member 4
chr5_-_28415166 0.22 ENSMUST00000117098.2
canopy FGF signaling regulator 1
chr12_-_56583582 0.22 ENSMUST00000001536.9
NK2 homeobox 1
chr2_+_24076481 0.22 ENSMUST00000057567.3
interleukin 1 family, member 9
chr2_-_57014015 0.22 ENSMUST00000112629.8
nuclear receptor subfamily 4, group A, member 2
chr1_-_14374794 0.21 ENSMUST00000190337.7
EYA transcriptional coactivator and phosphatase 1
chr6_+_48566540 0.21 ENSMUST00000204521.2
predicted gene 45021
chr8_+_3550533 0.21 ENSMUST00000208306.2
mucolipin 1
chr14_+_55813074 0.21 ENSMUST00000022826.7
fat storage-inducing transmembrane protein 1
chr15_+_76211597 0.21 ENSMUST00000059045.8
exosome component 4
chr1_-_14374842 0.20 ENSMUST00000188857.7
ENSMUST00000185453.7
EYA transcriptional coactivator and phosphatase 1
chr14_-_52151537 0.20 ENSMUST00000227402.2
ENSMUST00000227237.2
N-myc downstream regulated gene 2
chr10_-_95158827 0.20 ENSMUST00000220279.2
CASP2 and RIPK1 domain containing adaptor with death domain
chrX_+_67805443 0.20 ENSMUST00000069731.12
ENSMUST00000114647.8
Fmr1 neighbor
chr16_-_93400691 0.20 ENSMUST00000023669.14
ENSMUST00000233931.2
ENSMUST00000154355.3
SET domain containing 4
chr7_-_142453722 0.19 ENSMUST00000000219.10
tyrosine hydroxylase
chr10_-_18619658 0.19 ENSMUST00000215836.2
ARFGEF family member 3
chr18_+_76192529 0.19 ENSMUST00000167921.2
zinc finger and BTB domain containing 7C
chr18_-_3280999 0.19 ENSMUST00000049942.13
cAMP responsive element modulator
chrX_-_63320543 0.19 ENSMUST00000114679.2
ENSMUST00000069926.14
SLIT and NTRK-like family, member 4
chr11_-_79394904 0.18 ENSMUST00000164465.3
oligodendrocyte myelin glycoprotein
chr7_-_105230479 0.18 ENSMUST00000191601.7
amyloid beta (A4) precursor protein-binding, family B, member 1
chr7_+_27879650 0.18 ENSMUST00000172467.8
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1b
chr1_+_160806194 0.18 ENSMUST00000064725.11
ENSMUST00000191936.2
serine (or cysteine) peptidase inhibitor, clade C (antithrombin), member 1
chr11_-_74228857 0.18 ENSMUST00000214490.2
olfactory receptor 410
chr13_-_24118139 0.18 ENSMUST00000052776.4
H2B clustered histone 1
chr10_+_32959472 0.18 ENSMUST00000095762.5
ENSMUST00000218281.2
ENSMUST00000217779.2
ENSMUST00000219665.2
ENSMUST00000219931.2
triadin
chr13_-_23882437 0.18 ENSMUST00000102967.3
H4 clustered histone 3
chr19_+_6144449 0.18 ENSMUST00000235513.2
predicted gene 550
chr8_+_120588977 0.18 ENSMUST00000034287.10
kelch-like 36
chr6_+_137387718 0.18 ENSMUST00000167002.4
protein tyrosine phosphatase, receptor type, O
chr11_-_74228504 0.18 ENSMUST00000213831.2
olfactory receptor 410
chr18_+_61096597 0.18 ENSMUST00000115295.9
calcium/calmodulin-dependent protein kinase II alpha
chr5_+_92534738 0.18 ENSMUST00000128246.8
ADP-ribosyltransferase 3
chr1_+_160806241 0.17 ENSMUST00000195760.2
serine (or cysteine) peptidase inhibitor, clade C (antithrombin), member 1
chr8_+_95584146 0.17 ENSMUST00000211939.2
ENSMUST00000212124.2
polymerase (RNA) II (DNA directed) polypeptide C
chr7_+_81220987 0.17 ENSMUST00000165460.2
WAS protein homolog associated with actin, golgi membranes and microtubules
chr11_+_54195006 0.17 ENSMUST00000108904.10
ENSMUST00000108905.10
acyl-CoA synthetase long-chain family member 6
chr18_+_37093321 0.17 ENSMUST00000192168.2
protocadherin alpha 5
chr5_-_134935579 0.17 ENSMUST00000201316.4
ENSMUST00000047305.6
transmembrane protein 270
chr2_-_30068433 0.17 ENSMUST00000100220.5
SPOUT domain containing methyltransferase 1
chr7_-_101749433 0.17 ENSMUST00000106937.8
ADP-ribosyltransferase 5
chr7_+_101546059 0.17 ENSMUST00000143835.8
anaphase promoting complex C subunit 15
chrX_-_88453295 0.17 ENSMUST00000113959.8
ENSMUST00000113960.3
DDB1 and CUL4 associated factor 8 like
chr9_-_54554483 0.16 ENSMUST00000128163.8
acyl-CoA synthetase bubblegum family member 1
chr15_-_102630589 0.16 ENSMUST00000023818.11
calcium binding and coiled coil domain 1
chr2_+_111205867 0.16 ENSMUST00000062407.6
olfactory receptor 1284
chr2_+_164328375 0.16 ENSMUST00000069385.15
ENSMUST00000143690.8
dysbindin (dystrobrevin binding protein 1) domain containing 2
chr7_+_15863679 0.16 ENSMUST00000211649.2
solute carrier family 8 (sodium/calcium exchanger), member 2
chr14_-_36832044 0.16 ENSMUST00000179488.3
RIKEN cDNA 2610528A11 gene
chr6_-_68857658 0.16 ENSMUST00000198756.2
predicted gene 42543
chr2_+_31204314 0.16 ENSMUST00000113532.9
hemicentin 2
chr11_+_54194831 0.15 ENSMUST00000000145.12
ENSMUST00000138515.8
acyl-CoA synthetase long-chain family member 6
chr1_+_15382676 0.15 ENSMUST00000170146.3
potassium voltage gated channel, Shab-related subfamily, member 2
chr11_+_54194624 0.15 ENSMUST00000093106.12
acyl-CoA synthetase long-chain family member 6
chr4_+_43851565 0.15 ENSMUST00000107860.3
olfactory receptor 155
chr14_+_53743184 0.15 ENSMUST00000103583.5
T cell receptor alpha variable 10
chr1_+_78794475 0.15 ENSMUST00000057262.8
ENSMUST00000187432.2
potassium voltage-gated channel, Isk-related subfamily, gene 4
chr16_-_17019352 0.15 ENSMUST00000090192.12
ubiquitin-conjugating enzyme E2L 3
chr7_+_143420586 0.15 ENSMUST00000152910.3
ENSMUST00000207630.2
actin, epsilon 1
chr8_+_3550450 0.14 ENSMUST00000004683.13
ENSMUST00000160338.2
mucolipin 1
chrX_-_72442342 0.14 ENSMUST00000180787.3
predicted gene, 18336
chr3_-_154760978 0.14 ENSMUST00000064076.6
TNNI3 interacting kinase
chr2_-_87838612 0.14 ENSMUST00000215457.2
olfactory receptor 1160
chr3_-_64049349 0.14 ENSMUST00000177151.9
vomeronasal 2, receptor 2
chr7_-_104570689 0.14 ENSMUST00000217177.2
olfactory receptor 667
chr9_+_102382949 0.14 ENSMUST00000039390.6
kyphoscoliosis peptidase
chr6_+_137387729 0.14 ENSMUST00000203914.2
protein tyrosine phosphatase, receptor type, O
chr17_-_18498018 0.14 ENSMUST00000172190.4
ENSMUST00000231815.3
vomeronasal 2, receptor 94
chr9_-_55917834 0.14 ENSMUST00000217105.2
RIKEN cDNA 4930563M21 gene
chr17_+_44337566 0.14 ENSMUST00000229939.2
regulator of calcineurin 2
chr4_+_156300325 0.13 ENSMUST00000105572.3
PPARGC1 and ESRR induced regulator, muscle 1
chr11_-_53509485 0.13 ENSMUST00000000889.7
interleukin 4
chr12_-_40249489 0.13 ENSMUST00000220951.2
leucine-rich single-pass membrane protein 1
chr5_+_140404997 0.13 ENSMUST00000100507.8
eukaryotic translation initiation factor 3, subunit B
chr14_-_51134930 0.13 ENSMUST00000227271.2
kelch-like 33
chr7_-_105230395 0.13 ENSMUST00000188726.2
ENSMUST00000188440.7
amyloid beta (A4) precursor protein-binding, family B, member 1
chr3_-_123029782 0.13 ENSMUST00000106427.8
ENSMUST00000198584.2
synaptopodin 2
chr18_-_3281089 0.13 ENSMUST00000139537.2
ENSMUST00000124747.8
cAMP responsive element modulator
chr19_-_11291805 0.13 ENSMUST00000187467.2
membrane-spanning 4-domains, subfamily A, member 14
chr13_+_83672389 0.13 ENSMUST00000200394.5
myocyte enhancer factor 2C
chr2_+_80122811 0.12 ENSMUST00000057072.6
peroxiredoxin 6B
chr5_-_143963413 0.12 ENSMUST00000031622.13
oncomodulin
chr18_+_66006119 0.12 ENSMUST00000025395.10
gastrin releasing peptide
chr8_+_20478993 0.12 ENSMUST00000211848.2
predicted gene, 31371
chr7_+_99384352 0.12 ENSMUST00000098264.2
olfactory receptor 520
chr1_-_4430481 0.12 ENSMUST00000027032.6
retinitis pigmentosa 1 (human)
chr10_-_21943978 0.12 ENSMUST00000092672.6
RIKEN cDNA 4930444G20 gene
chr2_+_79538124 0.12 ENSMUST00000090760.9
ENSMUST00000040863.11
ENSMUST00000111780.3
protein phosphatase 1, regulatory inhibitor subunit 1C
chr15_+_94527117 0.12 ENSMUST00000080141.6
transmembrane protein 117
chr7_-_25374472 0.12 ENSMUST00000108404.8
ENSMUST00000108405.2
ENSMUST00000079439.10
transmembrane protein 91
chr1_-_39844467 0.12 ENSMUST00000171319.4
predicted gene 3646
chr5_+_73164226 0.11 ENSMUST00000031127.11
ENSMUST00000201304.2
solute carrier family 10 (sodium/bile acid cotransporter family), member 4
chr18_+_37646674 0.11 ENSMUST00000061405.6
protocadherin beta 21
chr6_-_55109960 0.11 ENSMUST00000003568.15
corticotropin releasing hormone receptor 2
chr2_-_87798643 0.11 ENSMUST00000099841.4
olfactory receptor 1157
chr18_-_3299536 0.11 ENSMUST00000129435.8
ENSMUST00000122958.8
cAMP responsive element modulator
chr11_-_101315345 0.11 ENSMUST00000107257.8
ENSMUST00000107259.4
ENSMUST00000107252.9
ENSMUST00000093933.11
predicted gene, 27029
prostaglandin E synthase 3 like
chr9_-_19799300 0.11 ENSMUST00000079660.5
olfactory receptor 862
chr18_+_66005891 0.11 ENSMUST00000173985.10
gastrin releasing peptide
chr2_+_164328763 0.11 ENSMUST00000109349.9
dysbindin (dystrobrevin binding protein 1) domain containing 2
chr14_+_26616514 0.11 ENSMUST00000238987.2
ENSMUST00000239004.2
ENSMUST00000165929.4
ENSMUST00000090337.12
ankyrin repeat and SOCS box-containing 14
chr2_-_79738734 0.11 ENSMUST00000090756.11
phosphodiesterase 1A, calmodulin-dependent
chr8_-_106670014 0.11 ENSMUST00000038896.8
lecithin cholesterol acyltransferase
chr17_-_20268598 0.11 ENSMUST00000168050.3
vomeronasal 2, receptor 104
chr8_-_13888389 0.11 ENSMUST00000071308.6
cDNA sequence AF366264
chr13_-_21826688 0.10 ENSMUST00000205631.3
olfactory receptor 11
chr7_+_144415115 0.10 ENSMUST00000060336.5
fibroblast growth factor 4

Network of associatons between targets according to the STRING database.

First level regulatory network of Mef2b

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 2.3 GO:0019287 isopentenyl diphosphate biosynthetic process, mevalonate pathway(GO:0019287)
0.5 6.9 GO:0015747 urate transport(GO:0015747)
0.5 1.4 GO:0042694 muscle cell fate specification(GO:0042694)
0.3 1.0 GO:1903920 positive regulation of actin filament severing(GO:1903920)
0.3 2.3 GO:0061709 reticulophagy(GO:0061709)
0.2 1.7 GO:0015862 uridine transport(GO:0015862)
0.2 0.7 GO:1902080 regulation of calcium ion import into sarcoplasmic reticulum(GO:1902080) negative regulation of calcium ion import into sarcoplasmic reticulum(GO:1902081)
0.2 0.7 GO:0014809 regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809)
0.2 1.5 GO:0071313 cellular response to caffeine(GO:0071313)
0.2 0.8 GO:0070837 dehydroascorbic acid transport(GO:0070837)
0.2 0.5 GO:0048007 positive regulation of interleukin-4 biosynthetic process(GO:0045404) antigen processing and presentation of lipid antigen via MHC class Ib(GO:0048003) antigen processing and presentation, exogenous lipid antigen via MHC class Ib(GO:0048007)
0.1 1.2 GO:0042866 pyruvate biosynthetic process(GO:0042866)
0.1 0.8 GO:1904073 regulation of trophectodermal cell proliferation(GO:1904073) positive regulation of trophectodermal cell proliferation(GO:1904075)
0.1 0.9 GO:0098528 skeletal muscle fiber differentiation(GO:0098528)
0.1 0.5 GO:0010747 positive regulation of plasma membrane long-chain fatty acid transport(GO:0010747)
0.1 0.8 GO:0043569 negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.1 0.3 GO:1990926 short-term synaptic potentiation(GO:1990926)
0.1 0.5 GO:0090361 platelet-derived growth factor production(GO:0090360) regulation of platelet-derived growth factor production(GO:0090361)
0.1 1.3 GO:2000291 regulation of myoblast proliferation(GO:2000291)
0.1 0.3 GO:0035523 protein K29-linked deubiquitination(GO:0035523)
0.1 0.3 GO:0036058 filtration diaphragm assembly(GO:0036058) slit diaphragm assembly(GO:0036060)
0.1 0.2 GO:0021759 globus pallidus development(GO:0021759)
0.1 0.2 GO:0051866 general adaptation syndrome(GO:0051866)
0.1 0.3 GO:0051919 positive regulation of fibrinolysis(GO:0051919)
0.1 0.3 GO:1903984 positive regulation of TRAIL-activated apoptotic signaling pathway(GO:1903984)
0.1 0.2 GO:1901740 negative regulation of myoblast fusion(GO:1901740)
0.1 0.3 GO:0060356 leucine import(GO:0060356)
0.1 0.3 GO:0032747 positive regulation of interleukin-23 production(GO:0032747)
0.1 0.3 GO:0050760 thymidylate synthase biosynthetic process(GO:0050757) regulation of thymidylate synthase biosynthetic process(GO:0050758) negative regulation of thymidylate synthase biosynthetic process(GO:0050760)
0.1 1.7 GO:0019373 epoxygenase P450 pathway(GO:0019373)
0.1 0.4 GO:0007597 blood coagulation, intrinsic pathway(GO:0007597)
0.0 0.5 GO:0071494 cellular response to UV-C(GO:0071494)
0.0 0.2 GO:1900738 psychomotor behavior(GO:0036343) positive regulation of phospholipase C-activating G-protein coupled receptor signaling pathway(GO:1900738)
0.0 0.4 GO:0072513 positive regulation of secondary heart field cardioblast proliferation(GO:0072513)
0.0 0.7 GO:0071688 striated muscle myosin thick filament assembly(GO:0071688)
0.0 0.1 GO:2000422 regulation of eosinophil chemotaxis(GO:2000422) positive regulation of eosinophil chemotaxis(GO:2000424)
0.0 2.2 GO:0003009 skeletal muscle contraction(GO:0003009)
0.0 0.2 GO:0071051 polyadenylation-dependent snoRNA 3'-end processing(GO:0071051)
0.0 0.6 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.0 0.1 GO:0003169 coronary vein morphogenesis(GO:0003169)
0.0 0.2 GO:0042414 epinephrine metabolic process(GO:0042414)
0.0 0.3 GO:0015671 oxygen transport(GO:0015671)
0.0 1.0 GO:0010880 regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum(GO:0010880)
0.0 0.1 GO:0048687 positive regulation of sprouting of injured axon(GO:0048687) positive regulation of axon extension involved in regeneration(GO:0048691) positive regulation of retinal ganglion cell axon guidance(GO:1902336)
0.0 0.2 GO:0051661 maintenance of centrosome location(GO:0051661)
0.0 0.1 GO:2000293 regulation of defecation(GO:2000292) negative regulation of defecation(GO:2000293)
0.0 0.4 GO:0006977 DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest(GO:0006977)
0.0 0.1 GO:0002304 gamma-delta intraepithelial T cell differentiation(GO:0002304) CD8-positive, gamma-delta intraepithelial T cell differentiation(GO:0002305)
0.0 0.2 GO:1990034 calcium ion export from cell(GO:1990034)
0.0 0.2 GO:0010890 positive regulation of sequestering of triglyceride(GO:0010890)
0.0 0.3 GO:0001682 tRNA 5'-leader removal(GO:0001682)
0.0 0.3 GO:1902866 regulation of retina development in camera-type eye(GO:1902866)
0.0 0.1 GO:0036092 phosphatidylinositol-3-phosphate biosynthetic process(GO:0036092)
0.0 2.0 GO:0030239 myofibril assembly(GO:0030239)
0.0 0.2 GO:0098870 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.0 4.3 GO:0006941 striated muscle contraction(GO:0006941)
0.0 0.1 GO:1902310 positive regulation of peptidyl-serine dephosphorylation(GO:1902310)
0.0 0.1 GO:0075525 viral translational termination-reinitiation(GO:0075525)
0.0 0.3 GO:0098989 NMDA selective glutamate receptor signaling pathway(GO:0098989)
0.0 0.1 GO:0002874 regulation of chronic inflammatory response to antigenic stimulus(GO:0002874) regulation of cytokine activity(GO:0060300)
0.0 0.0 GO:0006649 phospholipid transfer to membrane(GO:0006649)
0.0 0.2 GO:0018026 peptidyl-lysine monomethylation(GO:0018026)
0.0 0.1 GO:0060591 chondroblast differentiation(GO:0060591)
0.0 0.2 GO:0016926 protein desumoylation(GO:0016926)
0.0 0.2 GO:1903025 regulation of RNA polymerase II regulatory region sequence-specific DNA binding(GO:1903025)
0.0 0.1 GO:0014850 response to muscle activity(GO:0014850)
0.0 0.0 GO:0090282 positive regulation of transcription involved in G2/M transition of mitotic cell cycle(GO:0090282)
0.0 0.5 GO:0051351 positive regulation of ligase activity(GO:0051351)
0.0 0.2 GO:2000298 regulation of Rho-dependent protein serine/threonine kinase activity(GO:2000298)
0.0 1.2 GO:0006096 glycolytic process(GO:0006096)
0.0 0.2 GO:0090527 actin filament reorganization(GO:0090527)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.2 GO:0033018 sarcoplasmic reticulum lumen(GO:0033018)
0.3 0.8 GO:0014801 longitudinal sarcoplasmic reticulum(GO:0014801)
0.2 1.3 GO:0005927 muscle tendon junction(GO:0005927)
0.1 1.6 GO:0097512 cardiac myofibril(GO:0097512)
0.1 2.2 GO:0005861 troponin complex(GO:0005861)
0.1 1.3 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.1 0.3 GO:1990622 CHOP-ATF3 complex(GO:1990622)
0.1 0.8 GO:0042567 insulin-like growth factor ternary complex(GO:0042567)
0.1 0.2 GO:0099573 glutamatergic postsynaptic density(GO:0099573)
0.1 1.7 GO:0005859 muscle myosin complex(GO:0005859)
0.1 0.6 GO:0016012 sarcoglycan complex(GO:0016012)
0.1 1.7 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.1 0.3 GO:0044218 other organism cell membrane(GO:0044218) other organism membrane(GO:0044279)
0.1 0.3 GO:0070033 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032) synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex(GO:0070033)
0.0 0.3 GO:0000172 ribonuclease MRP complex(GO:0000172)
0.0 0.3 GO:0005833 hemoglobin complex(GO:0005833)
0.0 0.6 GO:0001939 female pronucleus(GO:0001939)
0.0 0.6 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.0 2.3 GO:0005801 cis-Golgi network(GO:0005801)
0.0 0.5 GO:0005916 fascia adherens(GO:0005916)
0.0 0.3 GO:1990761 growth cone lamellipodium(GO:1990761) growth cone filopodium(GO:1990812)
0.0 0.2 GO:0033162 melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.0 1.6 GO:0016459 myosin complex(GO:0016459)
0.0 4.4 GO:0031674 I band(GO:0031674)
0.0 1.9 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.0 0.2 GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.0 0.2 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
0.0 0.4 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.0 0.1 GO:0071547 piP-body(GO:0071547)
0.0 0.3 GO:0043194 axon initial segment(GO:0043194)
0.0 0.1 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
0.0 0.1 GO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 2.3 GO:0051373 FATZ binding(GO:0051373)
0.4 1.2 GO:0004794 L-threonine ammonia-lyase activity(GO:0004794)
0.4 6.9 GO:1901702 urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.2 1.6 GO:0004769 steroid delta-isomerase activity(GO:0004769)
0.2 2.2 GO:0031014 troponin T binding(GO:0031014)
0.2 0.6 GO:0050508 glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.2 0.6 GO:0016501 prostacyclin receptor activity(GO:0016501)
0.2 0.8 GO:0033300 dehydroascorbic acid transporter activity(GO:0033300)
0.1 1.0 GO:0061629 RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629)
0.1 0.7 GO:0005332 gamma-aminobutyric acid:sodium symporter activity(GO:0005332)
0.1 1.9 GO:0097493 structural molecule activity conferring elasticity(GO:0097493)
0.1 0.3 GO:0000171 ribonuclease MRP activity(GO:0000171)
0.1 1.3 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.1 0.3 GO:0031721 hemoglobin alpha binding(GO:0031721)
0.1 0.4 GO:0072345 NAADP-sensitive calcium-release channel activity(GO:0072345)
0.1 0.5 GO:0071723 lipopeptide binding(GO:0071723)
0.1 0.3 GO:1904288 BAT3 complex binding(GO:1904288)
0.1 2.1 GO:0070330 aromatase activity(GO:0070330)
0.1 0.5 GO:0061676 importin-alpha family protein binding(GO:0061676)
0.0 0.3 GO:1990050 phosphatidic acid transporter activity(GO:1990050)
0.0 0.2 GO:0034617 tetrahydrobiopterin binding(GO:0034617)
0.0 0.2 GO:0003953 NAD+ nucleosidase activity(GO:0003953)
0.0 2.3 GO:0016776 phosphotransferase activity, phosphate group as acceptor(GO:0016776)
0.0 0.1 GO:0005136 interleukin-4 receptor binding(GO:0005136)
0.0 0.8 GO:0004745 retinol dehydrogenase activity(GO:0004745)
0.0 0.4 GO:0001055 RNA polymerase II activity(GO:0001055)
0.0 0.6 GO:0102391 decanoate--CoA ligase activity(GO:0102391)
0.0 1.4 GO:0003785 actin monomer binding(GO:0003785)
0.0 0.3 GO:0001730 2'-5'-oligoadenylate synthetase activity(GO:0001730)
0.0 0.1 GO:0031013 troponin I binding(GO:0031013)
0.0 0.6 GO:0004129 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 0.1 GO:0016316 phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316) phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity(GO:0034597)
0.0 0.6 GO:0031005 filamin binding(GO:0031005)
0.0 0.4 GO:0070513 death domain binding(GO:0070513)
0.0 0.3 GO:1990405 protein antigen binding(GO:1990405)
0.0 0.1 GO:0004911 interleukin-2 receptor activity(GO:0004911)
0.0 0.2 GO:0097027 ubiquitin-protein transferase activator activity(GO:0097027)
0.0 0.1 GO:0031697 beta-1 adrenergic receptor binding(GO:0031697)
0.0 0.1 GO:0034584 piRNA binding(GO:0034584)
0.0 0.8 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.0 0.5 GO:0005337 nucleoside transmembrane transporter activity(GO:0005337)
0.0 0.1 GO:0034186 apolipoprotein A-I binding(GO:0034186)
0.0 0.1 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.0 0.1 GO:0004647 phosphoserine phosphatase activity(GO:0004647)
0.0 1.8 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.0 0.2 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.0 0.1 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.0 0.2 GO:0003956 NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956)
0.0 0.2 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.0 0.1 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.0 0.2 GO:0016929 SUMO-specific protease activity(GO:0016929)
0.0 0.8 GO:0001786 phosphatidylserine binding(GO:0001786)
0.0 0.2 GO:0048101 calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117) calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.0 0.2 GO:0001161 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161)
0.0 0.1 GO:0009019 tRNA (guanine-N1-)-methyltransferase activity(GO:0009019)
0.0 0.2 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.0 0.3 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.1 GO:0002046 opsin binding(GO:0002046)
0.0 0.3 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.0 0.4 GO:0000062 fatty-acyl-CoA binding(GO:0000062)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.4 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.0 0.9 ST WNT CA2 CYCLIC GMP PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.0 1.0 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.0 0.8 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.0 0.8 PID ER NONGENOMIC PATHWAY Plasma membrane estrogen receptor signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 6.1 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.1 2.3 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 0.7 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.0 1.7 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.0 1.3 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.0 0.3 REACTOME ACETYLCHOLINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Acetylcholine Neurotransmitter Release Cycle
0.0 0.4 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.0 0.4 REACTOME VIRAL MESSENGER RNA SYNTHESIS Genes involved in Viral Messenger RNA Synthesis
0.0 0.2 REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.0 0.3 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.0 0.3 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 0.3 REACTOME ACTIVATION OF GENES BY ATF4 Genes involved in Activation of Genes by ATF4
0.0 0.5 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs