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GSE58827: Dynamics of the Mouse Liver

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Results for Mef2d_Mef2a

Z-value: 1.65

Motif logo

Transcription factors associated with Mef2d_Mef2a

Gene Symbol Gene ID Gene Info
ENSMUSG00000001419.18 myocyte enhancer factor 2D
ENSMUSG00000030557.18 myocyte enhancer factor 2A

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Mef2dmm39_v1_chr3_+_88049633_88049790-0.353.6e-02Click!
Mef2amm39_v1_chr7_-_67022520_67022609-0.241.6e-01Click!

Activity profile of Mef2d_Mef2a motif

Sorted Z-values of Mef2d_Mef2a motif

Promoter Log-likelihood Transcript Gene Gene Info
chr7_-_97066937 11.51 ENSMUST00000043077.8
thyroid hormone responsive
chr14_+_55813074 11.32 ENSMUST00000022826.7
fat storage-inducing transmembrane protein 1
chr11_+_98274637 8.28 ENSMUST00000008021.3
titin-cap
chr1_-_66974492 8.07 ENSMUST00000120415.8
ENSMUST00000119429.8
myosin, light polypeptide 1
chr1_-_66974694 7.51 ENSMUST00000186202.7
myosin, light polypeptide 1
chr5_+_122239007 6.93 ENSMUST00000014080.13
ENSMUST00000111750.8
myosin, light polypeptide 2, regulatory, cardiac, slow
chr5_+_122239030 6.59 ENSMUST00000139213.8
ENSMUST00000111751.8
ENSMUST00000155612.8
myosin, light polypeptide 2, regulatory, cardiac, slow
chr19_+_20579322 6.15 ENSMUST00000087638.4
aldehyde dehydrogenase family 1, subfamily A1
chr7_-_48497771 6.10 ENSMUST00000032658.14
cysteine and glycine-rich protein 3
chr7_+_141995545 5.91 ENSMUST00000105971.8
ENSMUST00000145287.8
troponin I, skeletal, fast 2
chr10_+_87694117 5.78 ENSMUST00000122386.8
insulin-like growth factor 1
chr14_-_52151537 5.55 ENSMUST00000227402.2
ENSMUST00000227237.2
N-myc downstream regulated gene 2
chr3_-_122828592 5.46 ENSMUST00000029761.14
myozenin 2
chr14_-_52151026 5.35 ENSMUST00000228164.2
N-myc downstream regulated gene 2
chr5_+_135916764 4.93 ENSMUST00000005077.7
heat shock protein 1
chr8_+_110717062 4.71 ENSMUST00000001720.14
ENSMUST00000143741.2
tyrosine aminotransferase
chr5_+_135916847 4.60 ENSMUST00000111155.2
heat shock protein 1
chr9_+_74860133 4.58 ENSMUST00000215370.2
family with sequence similarity 214, member A
chr14_-_34310602 4.45 ENSMUST00000064098.14
ENSMUST00000090040.12
ENSMUST00000022330.9
ENSMUST00000022327.13
LIM domain binding 3
chr14_-_34310637 4.43 ENSMUST00000227819.2
LIM domain binding 3
chr1_-_66984178 4.36 ENSMUST00000027151.12
myosin, light polypeptide 1
chr11_+_67167950 4.33 ENSMUST00000019625.12
myosin, heavy polypeptide 8, skeletal muscle, perinatal
chr9_-_119852624 4.17 ENSMUST00000111635.4
xin actin-binding repeat containing 1
chr17_+_85335775 4.05 ENSMUST00000024944.9
solute carrier family 3, member 1
chr4_-_134099840 3.86 ENSMUST00000030643.3
exostosin-like glycosyltransferase 1
chr10_-_88440869 3.86 ENSMUST00000119185.8
ENSMUST00000238199.2
myosin binding protein C, slow-type
chr15_+_25940912 3.79 ENSMUST00000226438.2
reticulophagy regulator 1
chr1_-_172047282 3.74 ENSMUST00000170700.2
ENSMUST00000003554.11
calsequestrin 1
chr1_-_66984521 3.72 ENSMUST00000160100.2
myosin, light polypeptide 1
chr15_+_25940781 3.68 ENSMUST00000227275.2
reticulophagy regulator 1
chr6_-_71239216 3.53 ENSMUST00000129630.3
ENSMUST00000114186.9
ENSMUST00000074301.10
SET and MYND domain containing 1
chr11_+_67689094 3.51 ENSMUST00000168612.8
dehydrogenase/reductase (SDR family) member 7C
chr8_+_15107646 3.50 ENSMUST00000033842.4
myomesin 2
chr13_-_24118139 3.33 ENSMUST00000052776.4
H2B clustered histone 1
chr7_+_141996067 3.33 ENSMUST00000149529.8
troponin I, skeletal, fast 2
chr7_+_142052569 3.28 ENSMUST00000078497.15
ENSMUST00000105953.10
ENSMUST00000179658.8
ENSMUST00000105954.10
ENSMUST00000105952.10
ENSMUST00000105955.8
ENSMUST00000074187.13
ENSMUST00000169299.9
ENSMUST00000105957.10
ENSMUST00000180152.8
ENSMUST00000105950.11
ENSMUST00000105958.10
ENSMUST00000105949.8
troponin T3, skeletal, fast
chr15_+_25940931 3.25 ENSMUST00000110438.3
reticulophagy regulator 1
chr2_-_25359752 3.23 ENSMUST00000114259.3
ENSMUST00000015234.13
prostaglandin D2 synthase (brain)
chr7_+_80707328 3.15 ENSMUST00000107348.2
alpha-kinase 3
chr11_+_67090878 2.95 ENSMUST00000124516.8
ENSMUST00000018637.15
ENSMUST00000129018.8
myosin, heavy polypeptide 1, skeletal muscle, adult
chr2_+_90948481 2.91 ENSMUST00000137942.8
ENSMUST00000111430.10
ENSMUST00000169776.2
myosin binding protein C, cardiac
chr14_+_66205932 2.89 ENSMUST00000022616.14
clusterin
chr3_+_102981326 2.84 ENSMUST00000090715.13
ENSMUST00000155034.6
adenosine monophosphate deaminase 1
chr1_+_40844739 2.83 ENSMUST00000114765.4
transmembrane protein 182
chr11_-_94867153 2.78 ENSMUST00000103162.8
ENSMUST00000166320.8
sarcoglycan, alpha (dystrophin-associated glycoprotein)
chrX_+_100492684 2.73 ENSMUST00000033674.6
integrin beta 1 binding protein 2
chrX_-_94521712 2.70 ENSMUST00000033549.3
ankyrin repeat and SOCS box-containing 12
chr9_-_31824758 2.64 ENSMUST00000116615.5
BarH-like homeobox 2
chr2_+_102488985 2.63 ENSMUST00000080210.10
solute carrier family 1 (glial high affinity glutamate transporter), member 2
chr7_-_127805518 2.62 ENSMUST00000033049.9
cytochrome c oxidase subunit 6A2
chr10_-_88440996 2.55 ENSMUST00000121629.8
myosin binding protein C, slow-type
chrX_+_156481906 2.55 ENSMUST00000136141.2
ENSMUST00000190091.7
small muscle protein, X-linked
chr10_-_108846816 2.49 ENSMUST00000105276.8
ENSMUST00000064054.14
synaptotagmin I
chr14_-_34310438 2.49 ENSMUST00000228044.2
ENSMUST00000022328.14
LIM domain binding 3
chr4_+_133280680 2.39 ENSMUST00000042706.3
nuclear receptor subfamily 0, group B, member 2
chr13_+_89687915 2.26 ENSMUST00000022108.9
hyaluronan and proteoglycan link protein 1
chr2_-_25360043 2.22 ENSMUST00000114251.8
prostaglandin D2 synthase (brain)
chr2_-_33261498 2.20 ENSMUST00000113165.8
Ral GEF with PH domain and SH3 binding motif 1
chrX_+_156482116 2.18 ENSMUST00000112521.8
small muscle protein, X-linked
chr13_+_24118417 2.15 ENSMUST00000072391.2
H2A clustered histone 1
chr1_+_182392559 2.12 ENSMUST00000168514.7
calpain 8
chr9_+_121606750 2.12 ENSMUST00000098272.4
kelch-like 40
chr2_-_33261411 2.08 ENSMUST00000131298.7
ENSMUST00000091039.5
ENSMUST00000042615.13
Ral GEF with PH domain and SH3 binding motif 1
chr17_-_74257164 2.07 ENSMUST00000024866.6
xanthine dehydrogenase
chr7_+_127603083 2.05 ENSMUST00000106248.8
tripartite motif-containing 72
chr3_+_101993787 2.04 ENSMUST00000165540.9
ENSMUST00000164123.2
calsequestrin 2
chr2_+_69500444 2.00 ENSMUST00000100050.4
kelch-like 41
chr3_+_101993731 1.97 ENSMUST00000029454.12
calsequestrin 2
chr14_-_20718337 1.97 ENSMUST00000057090.12
ENSMUST00000117386.2
synaptopodin 2-like
chr18_-_3281089 1.97 ENSMUST00000139537.2
ENSMUST00000124747.8
cAMP responsive element modulator
chr3_-_142101339 1.96 ENSMUST00000198381.5
ENSMUST00000090134.12
ENSMUST00000196908.5
PDZ and LIM domain 5
chr9_+_110592709 1.94 ENSMUST00000079784.12
myosin, light polypeptide 3
chr13_-_36918424 1.93 ENSMUST00000037623.15
neuritin 1
chr13_+_23868175 1.93 ENSMUST00000018246.6
H2B clustered histone 4
chr9_-_70048766 1.91 ENSMUST00000034749.16
family with sequence similarity 81, member A
chr18_+_67597929 1.91 ENSMUST00000025411.9
PRELI domain containing 3A
chr3_-_95811993 1.91 ENSMUST00000147962.3
ENSMUST00000036181.15
carbonic anhydrase 14
chr5_-_113044216 1.90 ENSMUST00000086617.11
myosin XVIIIb
chr17_-_48739874 1.90 ENSMUST00000046549.5
apolipoprotein B mRNA editing enzyme, catalytic polypeptide 2
chr19_-_56378309 1.89 ENSMUST00000166203.2
ENSMUST00000167239.8
nebulin-related anchoring protein
chr2_-_32584132 1.88 ENSMUST00000028148.11
folylpolyglutamyl synthetase
chr6_+_121277186 1.84 ENSMUST00000064580.14
solute carrier family 6 (neurotransmitter transporter, GABA), member 13
chr11_+_70548513 1.83 ENSMUST00000134087.8
enolase 3, beta muscle
chr2_+_71884943 1.83 ENSMUST00000028525.6
Rap guanine nucleotide exchange factor (GEF) 4
chr6_+_121277693 1.83 ENSMUST00000142419.2
solute carrier family 6 (neurotransmitter transporter, GABA), member 13
chr18_-_39062201 1.82 ENSMUST00000134864.2
fibroblast growth factor 1
chr19_-_56378459 1.81 ENSMUST00000040711.15
ENSMUST00000095947.11
ENSMUST00000073536.13
nebulin-related anchoring protein
chr7_+_101750943 1.80 ENSMUST00000033300.4
ADP-ribosyltransferase 1
chr1_+_132996237 1.80 ENSMUST00000239467.2
phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 beta
chrX_-_8059597 1.77 ENSMUST00000143223.2
ENSMUST00000033509.15
phenylalkylamine Ca2+ antagonist (emopamil) binding protein
chr7_-_30754792 1.77 ENSMUST00000206328.2
FXYD domain-containing ion transport regulator 1
chr7_-_30755007 1.71 ENSMUST00000206474.2
ENSMUST00000205807.2
ENSMUST00000039909.13
ENSMUST00000206305.2
ENSMUST00000205439.2
FXYD domain-containing ion transport regulator 1
chr7_-_4517559 1.70 ENSMUST00000163538.8
troponin T1, skeletal, slow
chr12_+_41074089 1.65 ENSMUST00000132121.8
IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae)
chr12_+_41074328 1.64 ENSMUST00000134965.8
IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae)
chr15_-_78090591 1.61 ENSMUST00000120592.2
parvalbumin
chr1_+_182392577 1.61 ENSMUST00000048941.14
calpain 8
chr8_+_46111703 1.59 ENSMUST00000134675.8
ENSMUST00000139869.8
ENSMUST00000126067.8
sorbin and SH3 domain containing 2
chr18_-_39062514 1.59 ENSMUST00000235922.2
fibroblast growth factor 1
chr11_+_94219046 1.57 ENSMUST00000021227.6
ankyrin repeat domain 40
chr2_+_32515442 1.56 ENSMUST00000113277.8
ENSMUST00000195721.6
adenylate kinase 1
chr11_+_70548022 1.55 ENSMUST00000157027.8
ENSMUST00000072841.12
ENSMUST00000108548.8
ENSMUST00000126241.8
enolase 3, beta muscle
chr5_-_113229445 1.53 ENSMUST00000131708.2
ENSMUST00000117143.8
ENSMUST00000119627.8
crystallin, beta B3
chr13_+_102830104 1.53 ENSMUST00000172138.2
CD180 antigen
chr10_-_24588030 1.49 ENSMUST00000105520.8
ectonucleotide pyrophosphatase/phosphodiesterase 1
chr1_-_172125555 1.46 ENSMUST00000085913.11
ENSMUST00000097464.4
ATPase, Na+/K+ transporting, alpha 2 polypeptide
chr7_-_4517608 1.46 ENSMUST00000166959.8
troponin T1, skeletal, slow
chr12_+_108300599 1.45 ENSMUST00000021684.6
cytochrome P450, family 46, subfamily a, polypeptide 1
chr3_-_142101418 1.44 ENSMUST00000029941.16
ENSMUST00000058626.9
PDZ and LIM domain 5
chr11_-_77784922 1.39 ENSMUST00000017597.5
pipecolic acid oxidase
chr17_-_45903494 1.38 ENSMUST00000163492.8
solute carrier family 29 (nucleoside transporters), member 1
chr15_+_25940859 1.37 ENSMUST00000226750.2
reticulophagy regulator 1
chr15_-_76906832 1.36 ENSMUST00000019037.10
ENSMUST00000169226.9
myoglobin
chr10_-_24587884 1.36 ENSMUST00000135846.2
ectonucleotide pyrophosphatase/phosphodiesterase 1
chr16_+_8331293 1.35 ENSMUST00000065987.14
ENSMUST00000115838.8
ENSMUST00000115839.9
4-aminobutyrate aminotransferase
chr16_-_35589726 1.34 ENSMUST00000023554.9
solute carrier family 49 member 4
chr3_-_95789505 1.33 ENSMUST00000159863.2
ENSMUST00000159739.8
ENSMUST00000036418.10
ENSMUST00000161866.8
circadian associated repressor of transcription
chr3_-_137849113 1.32 ENSMUST00000098580.6
microsomal triglyceride transfer protein
chr6_+_53264255 1.30 ENSMUST00000203528.3
cAMP responsive element binding protein 5
chr14_-_20714634 1.29 ENSMUST00000119483.2
synaptopodin 2-like
chr5_+_92534738 1.29 ENSMUST00000128246.8
ADP-ribosyltransferase 3
chr12_-_84447702 1.29 ENSMUST00000122194.8
ectonucleoside triphosphate diphosphohydrolase 5
chr19_-_34856853 1.26 ENSMUST00000036584.13
pantothenate kinase 1
chrX_+_106299484 1.21 ENSMUST00000101294.9
ENSMUST00000118820.8
ENSMUST00000120971.8
G protein-coupled receptor 174
chr1_+_180678677 1.20 ENSMUST00000038091.8
SDE2 telomere maintenance homolog (S. pombe)
chr17_-_36208265 1.20 ENSMUST00000148721.8
RIKEN cDNA 2310061I04 gene
chr17_+_50816296 1.20 ENSMUST00000043938.8
phospholipase C-like 2
chr2_-_77000878 1.19 ENSMUST00000111833.3
coiled-coil domain containing 141
chr18_-_12995395 1.18 ENSMUST00000121888.8
oxysterol binding protein-like 1A
chr6_-_116050081 1.18 ENSMUST00000173548.3
transmembrane and coiled coil domains 1
chr18_-_12995261 1.17 ENSMUST00000234427.2
oxysterol binding protein-like 1A
chr3_+_102981352 1.17 ENSMUST00000176440.2
adenosine monophosphate deaminase 1
chr8_+_46111310 1.16 ENSMUST00000153798.8
sorbin and SH3 domain containing 2
chr9_+_102382949 1.15 ENSMUST00000039390.6
kyphoscoliosis peptidase
chr11_-_69260203 1.13 ENSMUST00000092971.13
ENSMUST00000108661.8
chromodomain helicase DNA binding protein 3
chr3_+_96484294 1.13 ENSMUST00000148290.2
predicted gene 16253
chr2_+_3514071 1.13 ENSMUST00000036350.3
cerebral dopamine neurotrophic factor
chr11_+_77353431 1.11 ENSMUST00000130255.2
coronin 6
chr8_+_77628916 1.07 ENSMUST00000109912.8
ENSMUST00000128862.2
ENSMUST00000109911.8
nuclear receptor subfamily 3, group C, member 2
chr11_+_108811626 1.05 ENSMUST00000140821.2
axin 2
chr12_-_84447625 1.05 ENSMUST00000117286.2
ectonucleoside triphosphate diphosphohydrolase 5
chr15_+_9140685 1.04 ENSMUST00000090380.6
LMBR1 domain containing 2
chr16_-_4340920 1.04 ENSMUST00000090500.10
ENSMUST00000023161.8
sarcalumenin
chr7_+_27879650 1.03 ENSMUST00000172467.8
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1b
chr5_-_24745970 1.03 ENSMUST00000117900.8
ankyrin repeat and SOCS box-containing 10
chr18_-_3280999 1.03 ENSMUST00000049942.13
cAMP responsive element modulator
chr4_-_73869071 1.02 ENSMUST00000095023.2
ENSMUST00000030101.4
RIKEN cDNA 2310002L09 gene
chr1_+_135727571 1.02 ENSMUST00000148201.8
troponin I, skeletal, slow 1
chr8_+_46111361 1.02 ENSMUST00000210946.2
sorbin and SH3 domain containing 2
chr1_+_131671751 1.00 ENSMUST00000049027.10
solute carrier family 26, member 9
chr4_-_44066960 1.00 ENSMUST00000173234.8
ENSMUST00000173274.2
glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase
chr6_+_42263609 0.99 ENSMUST00000238845.2
ENSMUST00000031894.13
chloride channel, voltage-sensitive 1
chr2_+_32518402 0.98 ENSMUST00000156578.8
adenylate kinase 1
chr2_+_19662529 0.98 ENSMUST00000052168.6
OTU domain containing 1
chr4_+_134042423 0.97 ENSMUST00000105875.8
ENSMUST00000030638.7
tripartite motif-containing 63
chr16_-_90866032 0.97 ENSMUST00000035689.8
ENSMUST00000114076.2
RIKEN cDNA 4932438H23 gene
chr1_+_16758731 0.97 ENSMUST00000190366.2
lymphocyte antigen 96
chr7_-_101749433 0.95 ENSMUST00000106937.8
ADP-ribosyltransferase 5
chr1_+_16758629 0.95 ENSMUST00000026881.11
lymphocyte antigen 96
chr3_+_32871669 0.95 ENSMUST00000072312.12
ENSMUST00000108228.8
ubiquitin specific peptidase 13 (isopeptidase T-3)
chr17_-_45903188 0.94 ENSMUST00000164769.8
solute carrier family 29 (nucleoside transporters), member 1
chr5_+_28370687 0.94 ENSMUST00000036177.9
engrailed 2
chr7_+_27878894 0.94 ENSMUST00000085901.13
ENSMUST00000172761.8
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1b
chr18_+_37606591 0.93 ENSMUST00000050034.3
protocadherin beta 15
chr1_+_135727140 0.93 ENSMUST00000152208.8
ENSMUST00000152075.8
troponin I, skeletal, slow 1
chr1_-_64161415 0.90 ENSMUST00000135075.2
Kruppel-like factor 7 (ubiquitous)
chr7_-_4517367 0.90 ENSMUST00000166161.8
troponin T1, skeletal, slow
chr1_+_187341225 0.90 ENSMUST00000110939.8
estrogen-related receptor gamma
chr2_+_27055245 0.89 ENSMUST00000000910.7
dopamine beta hydroxylase
chr1_+_135727228 0.89 ENSMUST00000154463.8
ENSMUST00000139986.8
troponin I, skeletal, slow 1
chrX_+_163221035 0.87 ENSMUST00000033755.6
ankyrin repeat and SOCS box-containing 11
chr17_-_45903410 0.86 ENSMUST00000166119.8
solute carrier family 29 (nucleoside transporters), member 1
chr15_-_95426108 0.86 ENSMUST00000075275.3
NEL-like 2
chr9_-_58462720 0.86 ENSMUST00000165365.3
CD276 antigen
chr11_+_94218810 0.85 ENSMUST00000107818.9
ENSMUST00000051221.13
ankyrin repeat domain 40
chr1_+_130947580 0.85 ENSMUST00000016673.6
interleukin 10
chr7_-_127423641 0.85 ENSMUST00000106267.5
syntaxin 1B
chr15_-_98705791 0.84 ENSMUST00000075444.8
dendrin
chr1_-_89942299 0.83 ENSMUST00000086882.8
ENSMUST00000097656.10
ankyrin repeat and SOCS box-containing 18
chr2_-_48839218 0.83 ENSMUST00000090976.10
ENSMUST00000149679.8
origin recognition complex, subunit 4
chr5_-_51711237 0.83 ENSMUST00000132734.8
peroxisome proliferative activated receptor, gamma, coactivator 1 alpha
chr10_+_34359395 0.83 ENSMUST00000019913.15
fyn-related kinase
chr3_+_137849189 0.82 ENSMUST00000040321.13
tRNA methyltransferase 10A
chr3_-_123029782 0.82 ENSMUST00000106427.8
ENSMUST00000198584.2
synaptopodin 2
chrX_-_46981273 0.81 ENSMUST00000153548.9
ENSMUST00000141084.3
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1
chr6_+_95094721 0.80 ENSMUST00000032107.10
ENSMUST00000119582.3
kelch repeat and BTB (POZ) domain containing 8
chr6_+_137387718 0.79 ENSMUST00000167002.4
protein tyrosine phosphatase, receptor type, O
chr1_+_187340952 0.79 ENSMUST00000127489.8
estrogen-related receptor gamma
chr10_+_69621337 0.78 ENSMUST00000182993.8
ankyrin 3, epithelial
chr6_+_42263644 0.77 ENSMUST00000163936.8
chloride channel, voltage-sensitive 1
chr9_-_110571645 0.77 ENSMUST00000006005.12
parathyroid hormone 1 receptor
chr3_+_122277372 0.77 ENSMUST00000197073.2
breast cancer anti-estrogen resistance 3
chr10_-_107330580 0.76 ENSMUST00000044210.5
myogenic factor 6
chr19_+_38253077 0.75 ENSMUST00000198045.5
leucine-rich repeat LGI family, member 1
chr5_+_138278502 0.75 ENSMUST00000160729.8
stromal antigen 3
chr14_+_66074751 0.75 ENSMUST00000022614.7
coiled-coil domain containing 25
chr7_+_16609227 0.74 ENSMUST00000108493.3
dishevelled-binding antagonist of beta-catenin 3
chr5_-_25047577 0.73 ENSMUST00000030787.9
Ras homolog enriched in brain
chr16_-_43836681 0.72 ENSMUST00000036174.10
GRAM domain containing 1C
chr3_+_20011251 0.72 ENSMUST00000108328.8
ceruloplasmin

Network of associatons between targets according to the STRING database.

First level regulatory network of Mef2d_Mef2a

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
4.5 13.5 GO:0042694 muscle cell fate specification(GO:0042694)
2.0 6.1 GO:1903920 positive regulation of actin filament severing(GO:1903920)
1.8 10.9 GO:0090360 platelet-derived growth factor production(GO:0090360) regulation of platelet-derived growth factor production(GO:0090361)
1.4 8.6 GO:0035995 detection of muscle stretch(GO:0035995)
1.4 11.3 GO:0010890 positive regulation of sequestering of triglyceride(GO:0010890)
1.3 12.1 GO:0061709 reticulophagy(GO:0061709)
1.1 3.3 GO:0061300 cerebellum vasculature development(GO:0061300)
1.1 9.5 GO:0038033 positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway(GO:0038033)
0.9 3.7 GO:0014809 regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809)
0.9 5.5 GO:2000255 negative regulation of male germ cell proliferation(GO:2000255)
0.8 5.8 GO:1904073 regulation of trophectodermal cell proliferation(GO:1904073) positive regulation of trophectodermal cell proliferation(GO:1904075)
0.7 6.1 GO:0042904 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.7 4.1 GO:0031444 slow-twitch skeletal muscle fiber contraction(GO:0031444)
0.6 1.9 GO:0046901 tetrahydrofolylpolyglutamate biosynthetic process(GO:0046901)
0.6 2.2 GO:0007522 visceral muscle development(GO:0007522)
0.5 4.7 GO:0006572 tyrosine catabolic process(GO:0006572)
0.5 1.6 GO:2000184 glomerular visceral epithelial cell apoptotic process(GO:1903210) regulation of glomerular visceral epithelial cell apoptotic process(GO:1904633) positive regulation of glomerular visceral epithelial cell apoptotic process(GO:1904635) positive regulation of progesterone biosynthetic process(GO:2000184)
0.5 3.4 GO:1901509 regulation of endothelial tube morphogenesis(GO:1901509)
0.5 1.0 GO:0014878 response to electrical stimulus involved in regulation of muscle adaptation(GO:0014878)
0.5 2.9 GO:1902998 regulation of neuronal signal transduction(GO:1902847) positive regulation of neurofibrillary tangle assembly(GO:1902998)
0.5 4.2 GO:0010880 regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum(GO:0010880)
0.5 1.4 GO:0006553 lysine metabolic process(GO:0006553)
0.5 3.2 GO:0015862 uridine transport(GO:0015862)
0.5 1.8 GO:0036092 phosphatidylinositol-3-phosphate biosynthetic process(GO:0036092)
0.4 4.0 GO:0071313 cellular response to caffeine(GO:0071313)
0.4 4.3 GO:0032485 regulation of Ral protein signal transduction(GO:0032485)
0.4 19.7 GO:0003009 skeletal muscle contraction(GO:0003009)
0.4 2.5 GO:0006172 ADP biosynthetic process(GO:0006172)
0.4 2.1 GO:0009115 xanthine catabolic process(GO:0009115)
0.4 4.0 GO:0032264 IMP salvage(GO:0032264)
0.4 3.5 GO:1903275 positive regulation of sodium ion export(GO:1903275) positive regulation of sodium ion export from cell(GO:1903278)
0.4 1.9 GO:0032497 detection of lipopolysaccharide(GO:0032497)
0.4 2.6 GO:0070777 D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.4 1.5 GO:0036060 filtration diaphragm assembly(GO:0036058) slit diaphragm assembly(GO:0036060)
0.4 1.8 GO:1904457 positive regulation of neuronal action potential(GO:1904457)
0.4 1.5 GO:1903279 regulation of calcium:sodium antiporter activity(GO:1903279)
0.3 1.0 GO:0014873 response to muscle activity involved in regulation of muscle adaptation(GO:0014873)
0.3 12.7 GO:0010866 regulation of triglyceride biosynthetic process(GO:0010866)
0.3 25.2 GO:0045214 sarcomere organization(GO:0045214)
0.3 2.5 GO:0005513 detection of calcium ion(GO:0005513)
0.3 1.2 GO:0002337 B-1a B cell differentiation(GO:0002337)
0.3 0.9 GO:0046333 octopamine biosynthetic process(GO:0006589) octopamine metabolic process(GO:0046333)
0.3 2.9 GO:0045719 negative regulation of glycogen biosynthetic process(GO:0045719)
0.3 0.9 GO:0060300 regulation of chronic inflammatory response to antigenic stimulus(GO:0002874) regulation of cytokine activity(GO:0060300)
0.3 1.4 GO:0009449 gamma-aminobutyric acid biosynthetic process(GO:0009449)
0.3 1.6 GO:0061181 regulation of mismatch repair(GO:0032423) regulation of chondrocyte development(GO:0061181) negative regulation of Wnt signaling pathway involved in dorsal/ventral axis specification(GO:2000054)
0.3 1.1 GO:0031959 mineralocorticoid receptor signaling pathway(GO:0031959)
0.3 2.1 GO:0098528 skeletal muscle fiber differentiation(GO:0098528)
0.3 3.1 GO:0042637 catagen(GO:0042637)
0.3 2.3 GO:0043569 negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.2 0.9 GO:0035523 protein K29-linked deubiquitination(GO:0035523)
0.2 0.6 GO:0046684 response to pyrethroid(GO:0046684)
0.2 2.5 GO:0098870 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.2 0.6 GO:2000537 regulation of cGMP-mediated signaling(GO:0010752) regulation of B cell chemotaxis(GO:2000537) positive regulation of B cell chemotaxis(GO:2000538)
0.2 1.0 GO:0007066 female meiosis sister chromatid cohesion(GO:0007066)
0.2 1.9 GO:0048739 cardiac muscle fiber development(GO:0048739)
0.2 0.4 GO:0060399 positive regulation of growth hormone receptor signaling pathway(GO:0060399)
0.2 0.5 GO:0040040 thermosensory behavior(GO:0040040)
0.2 0.9 GO:1904048 negative regulation of synaptic vesicle recycling(GO:1903422) regulation of spontaneous neurotransmitter secretion(GO:1904048)
0.2 0.5 GO:0071460 cellular response to cell-matrix adhesion(GO:0071460)
0.2 2.6 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.2 0.5 GO:0070563 negative regulation of vitamin D receptor signaling pathway(GO:0070563)
0.2 1.4 GO:0015671 oxygen transport(GO:0015671)
0.2 1.4 GO:0072513 positive regulation of secondary heart field cardioblast proliferation(GO:0072513)
0.1 0.4 GO:0055014 atrial cardiac muscle cell differentiation(GO:0055011) atrial cardiac muscle cell development(GO:0055014)
0.1 1.3 GO:0034196 acylglycerol transport(GO:0034196) triglyceride transport(GO:0034197)
0.1 1.9 GO:0016554 cytidine to uridine editing(GO:0016554)
0.1 0.3 GO:0086097 phospholipase C-activating angiotensin-activated signaling pathway(GO:0086097)
0.1 0.5 GO:0044208 'de novo' AMP biosynthetic process(GO:0044208)
0.1 0.5 GO:0090282 positive regulation of transcription involved in G2/M transition of mitotic cell cycle(GO:0090282)
0.1 0.5 GO:2000292 regulation of defecation(GO:2000292) negative regulation of defecation(GO:2000293)
0.1 0.8 GO:0048743 positive regulation of skeletal muscle fiber development(GO:0048743)
0.1 24.1 GO:0060048 cardiac muscle contraction(GO:0060048)
0.1 0.9 GO:0045077 negative regulation of interferon-gamma biosynthetic process(GO:0045077)
0.1 0.6 GO:0070885 negative regulation of calcineurin-NFAT signaling cascade(GO:0070885)
0.1 0.5 GO:0072023 ascending thin limb development(GO:0072021) thick ascending limb development(GO:0072023) metanephric ascending thin limb development(GO:0072218) metanephric thick ascending limb development(GO:0072233)
0.1 2.3 GO:0045821 positive regulation of glycolytic process(GO:0045821) positive regulation of cofactor metabolic process(GO:0051194) positive regulation of coenzyme metabolic process(GO:0051197)
0.1 1.5 GO:0006707 cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.1 0.4 GO:0098964 dendritic transport of ribonucleoprotein complex(GO:0098961) dendritic transport of messenger ribonucleoprotein complex(GO:0098963) anterograde dendritic transport of messenger ribonucleoprotein complex(GO:0098964)
0.1 1.0 GO:0006013 mannose metabolic process(GO:0006013)
0.1 3.5 GO:0045663 positive regulation of myoblast differentiation(GO:0045663)
0.1 0.6 GO:0003219 cardiac right ventricle formation(GO:0003219)
0.1 0.5 GO:0099525 presynaptic dense core granule exocytosis(GO:0099525)
0.1 1.1 GO:1902866 regulation of retina development in camera-type eye(GO:1902866)
0.1 0.4 GO:1904715 negative regulation of chaperone-mediated autophagy(GO:1904715)
0.1 0.5 GO:1990034 calcium ion export from cell(GO:1990034)
0.1 4.0 GO:0006471 protein ADP-ribosylation(GO:0006471)
0.1 0.8 GO:0014029 neural crest formation(GO:0014029)
0.1 0.4 GO:0051643 endoplasmic reticulum localization(GO:0051643)
0.1 0.4 GO:1902310 positive regulation of peptidyl-serine dephosphorylation(GO:1902310)
0.1 1.0 GO:2000298 regulation of Rho-dependent protein serine/threonine kinase activity(GO:2000298)
0.1 1.3 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
0.1 1.2 GO:0071286 cellular response to magnesium ion(GO:0071286)
0.1 0.7 GO:2000074 regulation of type B pancreatic cell development(GO:2000074)
0.1 0.4 GO:0046013 regulation of T cell homeostatic proliferation(GO:0046013)
0.1 0.6 GO:1900042 interleukin-4 secretion(GO:0072602) positive regulation of interleukin-2 secretion(GO:1900042)
0.1 0.9 GO:0098989 NMDA selective glutamate receptor signaling pathway(GO:0098989)
0.1 1.0 GO:0006047 UDP-N-acetylglucosamine metabolic process(GO:0006047)
0.1 0.2 GO:0051866 general adaptation syndrome(GO:0051866)
0.1 1.9 GO:0006825 copper ion transport(GO:0006825)
0.1 0.9 GO:0070050 development of secondary female sexual characteristics(GO:0046543) neuron cellular homeostasis(GO:0070050)
0.0 0.9 GO:1990403 embryonic brain development(GO:1990403)
0.0 1.1 GO:0014823 response to activity(GO:0014823)
0.0 3.3 GO:0060612 adipose tissue development(GO:0060612)
0.0 0.8 GO:0060732 positive regulation of inositol phosphate biosynthetic process(GO:0060732)
0.0 1.0 GO:0008272 sulfate transport(GO:0008272)
0.0 3.4 GO:0061001 regulation of dendritic spine morphogenesis(GO:0061001)
0.0 0.2 GO:0060023 soft palate development(GO:0060023)
0.0 1.3 GO:0045475 locomotor rhythm(GO:0045475)
0.0 0.7 GO:0035414 negative regulation of catenin import into nucleus(GO:0035414)
0.0 0.8 GO:0010960 magnesium ion homeostasis(GO:0010960)
0.0 3.0 GO:0006687 glycosphingolipid metabolic process(GO:0006687)
0.0 3.3 GO:0032233 positive regulation of actin filament bundle assembly(GO:0032233)
0.0 0.3 GO:0035902 response to immobilization stress(GO:0035902)
0.0 0.9 GO:0042761 fatty acid elongation(GO:0030497) very long-chain fatty acid biosynthetic process(GO:0042761)
0.0 0.1 GO:0044339 canonical Wnt signaling pathway involved in osteoblast differentiation(GO:0044339)
0.0 1.0 GO:0070536 protein K63-linked deubiquitination(GO:0070536)
0.0 0.7 GO:0005980 glycogen catabolic process(GO:0005980) glucan catabolic process(GO:0009251) cellular polysaccharide catabolic process(GO:0044247)
0.0 0.5 GO:0031581 hemidesmosome assembly(GO:0031581)
0.0 0.6 GO:0046475 glycerophospholipid catabolic process(GO:0046475)
0.0 1.4 GO:0006270 DNA replication initiation(GO:0006270)
0.0 1.3 GO:0051642 centrosome localization(GO:0051642)
0.0 0.9 GO:0055090 acylglycerol homeostasis(GO:0055090) triglyceride homeostasis(GO:0070328)
0.0 2.4 GO:0032024 positive regulation of insulin secretion(GO:0032024)
0.0 2.0 GO:0015914 phospholipid transport(GO:0015914)
0.0 1.8 GO:0006695 cholesterol biosynthetic process(GO:0006695)
0.0 0.6 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.0 1.4 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.0 1.1 GO:0071542 dopaminergic neuron differentiation(GO:0071542)
0.0 0.4 GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.0 0.5 GO:0035428 hexose transmembrane transport(GO:0035428)
0.0 0.1 GO:1903984 positive regulation of TRAIL-activated apoptotic signaling pathway(GO:1903984)
0.0 0.1 GO:1905150 regulation of voltage-gated sodium channel activity(GO:1905150)
0.0 1.2 GO:0043029 T cell homeostasis(GO:0043029)
0.0 0.5 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.0 0.6 GO:0003016 respiratory system process(GO:0003016)
0.0 1.4 GO:0048384 retinoic acid receptor signaling pathway(GO:0048384)
0.0 0.8 GO:0002089 lens morphogenesis in camera-type eye(GO:0002089)
0.0 0.1 GO:1904425 negative regulation of GTP binding(GO:1904425)
0.0 0.3 GO:0060789 hair follicle placode formation(GO:0060789)
0.0 0.3 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.0 1.1 GO:0007528 neuromuscular junction development(GO:0007528)
0.0 0.4 GO:0001886 endothelial cell morphogenesis(GO:0001886)
0.0 1.9 GO:0006885 regulation of pH(GO:0006885)
0.0 0.5 GO:0033141 positive regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033141)
0.0 1.2 GO:0007029 endoplasmic reticulum organization(GO:0007029)
0.0 3.2 GO:0006865 amino acid transport(GO:0006865)
0.0 1.0 GO:0043044 ATP-dependent chromatin remodeling(GO:0043044)
0.0 3.5 GO:0006486 protein glycosylation(GO:0006486) macromolecule glycosylation(GO:0043413)
0.0 0.0 GO:0060671 epithelial cell differentiation involved in embryonic placenta development(GO:0060671) epithelial cell morphogenesis involved in placental branching(GO:0060672)
0.0 1.3 GO:0038083 peptidyl-tyrosine autophosphorylation(GO:0038083)
0.0 0.3 GO:0001502 cartilage condensation(GO:0001502)
0.0 0.4 GO:0045109 intermediate filament organization(GO:0045109)
0.0 0.3 GO:0045662 negative regulation of myoblast differentiation(GO:0045662)
0.0 1.9 GO:0007601 visual perception(GO:0007601)
0.0 0.1 GO:0097106 positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388) postsynaptic density organization(GO:0097106)
0.0 0.2 GO:0002862 negative regulation of inflammatory response to antigenic stimulus(GO:0002862)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
2.6 7.8 GO:0033018 sarcoplasmic reticulum lumen(GO:0033018)
1.5 19.4 GO:0005861 troponin complex(GO:0005861)
1.3 25.5 GO:0097512 cardiac myofibril(GO:0097512)
1.2 3.5 GO:0014801 longitudinal sarcoplasmic reticulum(GO:0014801)
1.1 3.3 GO:0042720 mitochondrial inner membrane peptidase complex(GO:0042720)
1.1 8.7 GO:0005927 muscle tendon junction(GO:0005927)
0.6 15.3 GO:0005859 muscle myosin complex(GO:0005859)
0.6 5.8 GO:0042567 insulin-like growth factor ternary complex(GO:0042567)
0.5 1.6 GO:1990843 subsarcolemmal mitochondrion(GO:1990843) interfibrillar mitochondrion(GO:1990844)
0.5 5.0 GO:0032982 myosin filament(GO:0032982)
0.4 2.9 GO:0097441 basilar dendrite(GO:0097441)
0.4 1.8 GO:0044316 cone cell pedicle(GO:0044316)
0.3 1.0 GO:0090537 CERF complex(GO:0090537)
0.3 2.0 GO:0031430 M band(GO:0031430)
0.3 2.8 GO:0016012 sarcoglycan complex(GO:0016012)
0.3 0.9 GO:0060205 secretory granule lumen(GO:0034774) cytoplasmic membrane-bounded vesicle lumen(GO:0060205)
0.3 3.7 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.3 4.7 GO:0005916 fascia adherens(GO:0005916)
0.2 18.4 GO:0016459 myosin complex(GO:0016459)
0.2 1.9 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.2 0.7 GO:0099573 glutamatergic postsynaptic density(GO:0099573)
0.2 1.0 GO:0000802 transverse filament(GO:0000802)
0.2 2.5 GO:0001520 outer dense fiber(GO:0001520)
0.2 2.9 GO:0034366 spherical high-density lipoprotein particle(GO:0034366)
0.2 2.1 GO:0031672 A band(GO:0031672)
0.2 0.7 GO:0014701 junctional sarcoplasmic reticulum membrane(GO:0014701)
0.2 12.1 GO:0005801 cis-Golgi network(GO:0005801)
0.2 3.1 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.1 1.5 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.1 28.3 GO:0030018 Z disc(GO:0030018)
0.1 0.5 GO:0098831 presynaptic active zone cytoplasmic component(GO:0098831)
0.1 1.4 GO:0005664 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.1 2.5 GO:0030285 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.1 4.9 GO:0016529 sarcoplasmic reticulum(GO:0016529)
0.1 9.0 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.1 11.3 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)
0.1 0.6 GO:0031674 I band(GO:0031674)
0.1 4.6 GO:0034707 chloride channel complex(GO:0034707)
0.1 1.8 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.1 3.8 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.1 0.9 GO:0048787 presynaptic active zone membrane(GO:0048787)
0.1 2.3 GO:0030673 axolemma(GO:0030673)
0.0 0.3 GO:0005964 phosphorylase kinase complex(GO:0005964)
0.0 1.1 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.0 0.6 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.0 0.1 GO:0034680 integrin alpha10-beta1 complex(GO:0034680)
0.0 0.2 GO:1990923 PET complex(GO:1990923)
0.0 0.6 GO:0043034 costamere(GO:0043034)
0.0 0.5 GO:0032039 integrator complex(GO:0032039)
0.0 0.6 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.0 0.3 GO:0031983 vesicle lumen(GO:0031983)
0.0 0.1 GO:1990622 CHOP-ATF3 complex(GO:1990622)
0.0 0.6 GO:0071564 npBAF complex(GO:0071564)
0.0 0.3 GO:0071203 WASH complex(GO:0071203)
0.0 0.5 GO:0016528 sarcoplasm(GO:0016528)
0.0 0.3 GO:0042788 polysomal ribosome(GO:0042788)
0.0 0.4 GO:0045334 clathrin-coated endocytic vesicle(GO:0045334)
0.0 1.7 GO:0016328 lateral plasma membrane(GO:0016328)
0.0 1.9 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.0 1.8 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 0.6 GO:0001533 cornified envelope(GO:0001533)
0.0 1.3 GO:0030118 clathrin coat(GO:0030118)
0.0 1.7 GO:0043195 terminal bouton(GO:0043195)
0.0 0.5 GO:0005921 gap junction(GO:0005921)
0.0 0.5 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.0 0.8 GO:0030672 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.0 0.4 GO:0010369 chromocenter(GO:0010369)
0.0 0.6 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 0.5 GO:0032590 dendrite membrane(GO:0032590)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
2.7 13.7 GO:0051373 FATZ binding(GO:0051373)
1.6 4.7 GO:0080130 L-phenylalanine:2-oxoglutarate aminotransferase activity(GO:0080130)
1.5 6.1 GO:0031433 telethonin binding(GO:0031433)
1.4 5.5 GO:0004667 prostaglandin-D synthase activity(GO:0004667)
1.3 13.3 GO:0031014 troponin T binding(GO:0031014)
1.3 3.9 GO:0050508 glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
1.2 6.1 GO:0018479 benzaldehyde dehydrogenase (NAD+) activity(GO:0018479)
1.0 28.5 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.8 2.5 GO:0030348 syntaxin-3 binding(GO:0030348)
0.8 5.5 GO:0030899 calcium-dependent ATPase activity(GO:0030899)
0.6 1.9 GO:0004326 tetrahydrofolylpolyglutamate synthase activity(GO:0004326)
0.6 3.5 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.6 2.9 GO:0004528 phosphodiesterase I activity(GO:0004528)
0.5 3.7 GO:0005332 gamma-aminobutyric acid:sodium symporter activity(GO:0005332)
0.5 2.3 GO:0004382 guanosine-diphosphatase activity(GO:0004382)
0.4 2.6 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.4 2.1 GO:0030151 xanthine dehydrogenase activity(GO:0004854) oxidoreductase activity, acting on CH or CH2 groups, NAD or NADP as acceptor(GO:0016726) molybdenum ion binding(GO:0030151) molybdopterin cofactor binding(GO:0043546)
0.4 4.0 GO:0047623 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.4 1.1 GO:0017082 mineralocorticoid receptor activity(GO:0017082)
0.3 1.0 GO:0004572 mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity(GO:0004572)
0.3 1.9 GO:0001875 lipopolysaccharide receptor activity(GO:0001875)
0.3 1.9 GO:1990050 phosphatidic acid transporter activity(GO:1990050)
0.3 15.5 GO:0003785 actin monomer binding(GO:0003785)
0.3 0.9 GO:0004500 dopamine beta-monooxygenase activity(GO:0004500)
0.3 4.0 GO:0003956 NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956)
0.3 3.7 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.3 1.8 GO:0004769 steroid delta-isomerase activity(GO:0004769)
0.2 2.1 GO:0031432 titin binding(GO:0031432)
0.2 9.5 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.2 1.4 GO:0016647 oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor(GO:0016647)
0.2 1.3 GO:0004594 pantothenate kinase activity(GO:0004594)
0.2 1.9 GO:0004126 cytidine deaminase activity(GO:0004126)
0.2 1.0 GO:0008761 UDP-N-acetylglucosamine 2-epimerase activity(GO:0008761)
0.2 4.2 GO:0031005 filamin binding(GO:0031005)
0.2 0.9 GO:1904288 BAT3 complex binding(GO:1904288)
0.2 0.5 GO:0004019 adenylosuccinate synthase activity(GO:0004019)
0.2 2.5 GO:0004017 adenylate kinase activity(GO:0004017)
0.2 1.9 GO:0004322 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.2 0.7 GO:0008184 glycogen phosphorylase activity(GO:0008184)
0.2 3.4 GO:0044548 S100 protein binding(GO:0044548)
0.2 1.4 GO:0005344 oxygen transporter activity(GO:0005344)
0.1 3.5 GO:0004745 retinol dehydrogenase activity(GO:0004745)
0.1 3.4 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.1 0.4 GO:0004911 interleukin-2 receptor activity(GO:0004911)
0.1 5.8 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.1 1.5 GO:1990239 steroid hormone binding(GO:1990239)
0.1 2.9 GO:0051787 misfolded protein binding(GO:0051787)
0.1 0.8 GO:0009019 tRNA (guanine-N1-)-methyltransferase activity(GO:0009019)
0.1 0.8 GO:0004991 parathyroid hormone receptor activity(GO:0004991)
0.1 0.3 GO:0050262 ribosylnicotinamide kinase activity(GO:0050262) ribosylnicotinate kinase activity(GO:0061769)
0.1 3.1 GO:0015002 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.1 1.8 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.1 1.9 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.1 1.0 GO:0036310 annealing helicase activity(GO:0036310)
0.1 0.5 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
0.1 2.9 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.1 0.3 GO:0001596 angiotensin type I receptor activity(GO:0001596)
0.1 2.3 GO:0005540 hyaluronic acid binding(GO:0005540)
0.1 1.6 GO:0070411 I-SMAD binding(GO:0070411)
0.1 1.7 GO:0003708 retinoic acid receptor activity(GO:0003708)
0.1 1.8 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.1 0.6 GO:0043423 3-phosphoinositide-dependent protein kinase binding(GO:0043423)
0.1 1.4 GO:0003688 DNA replication origin binding(GO:0003688)
0.1 0.6 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.1 0.4 GO:0004647 phosphoserine phosphatase activity(GO:0004647)
0.1 1.5 GO:0005212 structural constituent of eye lens(GO:0005212)
0.1 1.2 GO:0102391 decanoate--CoA ligase activity(GO:0102391)
0.1 1.3 GO:0034185 apolipoprotein binding(GO:0034185)
0.1 3.5 GO:0018024 histone-lysine N-methyltransferase activity(GO:0018024)
0.1 0.3 GO:0002046 opsin binding(GO:0002046)
0.1 1.0 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.1 0.7 GO:0070097 delta-catenin binding(GO:0070097)
0.1 1.4 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.1 0.5 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.1 0.6 GO:0086080 protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
0.0 0.5 GO:0022820 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.0 0.3 GO:0004689 phosphorylase kinase activity(GO:0004689)
0.0 0.5 GO:0019992 diacylglycerol binding(GO:0019992)
0.0 0.6 GO:0019855 calcium channel inhibitor activity(GO:0019855)
0.0 2.4 GO:0001786 phosphatidylserine binding(GO:0001786)
0.0 0.5 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.0 0.4 GO:0008504 monoamine transmembrane transporter activity(GO:0008504)
0.0 0.7 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.0 1.5 GO:0017147 Wnt-protein binding(GO:0017147)
0.0 3.5 GO:0017022 myosin binding(GO:0017022)
0.0 0.5 GO:0086008 voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization(GO:0086008)
0.0 0.4 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.0 0.6 GO:0031402 sodium ion binding(GO:0031402)
0.0 1.4 GO:0008483 transaminase activity(GO:0008483)
0.0 1.8 GO:0030552 cAMP binding(GO:0030552)
0.0 0.2 GO:0099583 neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration(GO:0099583)
0.0 27.5 GO:0005509 calcium ion binding(GO:0005509)
0.0 0.4 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.0 2.4 GO:0015485 cholesterol binding(GO:0015485)
0.0 0.7 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.0 2.0 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.0 1.5 GO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen(GO:0016709)
0.0 0.5 GO:0004679 AMP-activated protein kinase activity(GO:0004679)
0.0 0.5 GO:0005132 type I interferon receptor binding(GO:0005132)
0.0 0.4 GO:0015491 cation:cation antiporter activity(GO:0015491)
0.0 0.6 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.0 0.1 GO:0098639 collagen binding involved in cell-matrix adhesion(GO:0098639)
0.0 0.8 GO:0005484 SNAP receptor activity(GO:0005484)
0.0 1.3 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0 0.5 GO:0030506 ankyrin binding(GO:0030506)
0.0 3.3 GO:0008236 serine-type peptidase activity(GO:0008236)
0.0 0.3 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.0 0.4 GO:0022829 wide pore channel activity(GO:0022829)
0.0 0.5 GO:0001223 transcription coactivator binding(GO:0001223)
0.0 0.3 GO:0000217 DNA secondary structure binding(GO:0000217)
0.0 0.8 GO:0036002 pre-mRNA binding(GO:0036002)
0.0 0.9 GO:0016627 oxidoreductase activity, acting on the CH-CH group of donors(GO:0016627)
0.0 1.1 GO:0003725 double-stranded RNA binding(GO:0003725)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 13.5 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.2 1.8 SIG PIP3 SIGNALING IN CARDIAC MYOCTES Genes related to PIP3 signaling in cardiac myocytes
0.2 10.8 ST P38 MAPK PATHWAY p38 MAPK Pathway
0.1 2.7 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.1 4.3 ST WNT CA2 CYCLIC GMP PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.1 5.8 PID ER NONGENOMIC PATHWAY Plasma membrane estrogen receptor signaling
0.1 9.0 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.1 0.6 PID FOXO PATHWAY FoxO family signaling
0.1 2.0 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.1 2.9 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.1 3.8 PID FGF PATHWAY FGF signaling pathway
0.1 1.9 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.1 2.3 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 1.6 PID BETA CATENIN DEG PATHWAY Degradation of beta catenin
0.0 3.8 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0 0.5 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 0.9 SIG CD40PATHWAYMAP Genes related to CD40 signaling
0.0 0.5 ST G ALPHA I PATHWAY G alpha i Pathway
0.0 0.9 PID AP1 PATHWAY AP-1 transcription factor network
0.0 0.4 PID RHODOPSIN PATHWAY Visual signal transduction: Rods
0.0 0.2 PID EPHA2 FWD PATHWAY EPHA2 forward signaling
0.0 0.9 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 0.8 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.0 0.5 PID CD8 TCR DOWNSTREAM PATHWAY Downstream signaling in naïve CD8+ T cells

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 66.5 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.6 6.1 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.2 2.5 REACTOME ACETYLCHOLINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Acetylcholine Neurotransmitter Release Cycle
0.2 3.7 REACTOME FGFR4 LIGAND BINDING AND ACTIVATION Genes involved in FGFR4 ligand binding and activation
0.2 4.0 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.1 1.9 REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1 Genes involved in IKK complex recruitment mediated by RIP1
0.1 9.5 REACTOME DESTABILIZATION OF MRNA BY AUF1 HNRNP D0 Genes involved in Destabilization of mRNA by AUF1 (hnRNP D0)
0.1 1.8 REACTOME DEFENSINS Genes involved in Defensins
0.1 2.1 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.1 1.4 REACTOME E2F ENABLED INHIBITION OF PRE REPLICATION COMPLEX FORMATION Genes involved in E2F-enabled inhibition of pre-replication complex formation
0.1 1.5 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.1 3.4 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.1 1.4 REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
0.1 1.2 REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.1 2.5 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.1 1.3 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.1 3.6 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.1 4.7 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.1 5.9 REACTOME AMINO ACID AND OLIGOPEPTIDE SLC TRANSPORTERS Genes involved in Amino acid and oligopeptide SLC transporters
0.1 2.0 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.1 0.9 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.1 1.8 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.1 2.3 REACTOME METAL ION SLC TRANSPORTERS Genes involved in Metal ion SLC transporters
0.0 1.0 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.0 1.3 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.0 0.9 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.0 1.7 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.0 0.5 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.0 0.6 REACTOME ACYL CHAIN REMODELLING OF PS Genes involved in Acyl chain remodelling of PS
0.0 1.8 REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.0 0.5 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0 1.2 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.0 0.9 REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF CAMKII Genes involved in CREB phosphorylation through the activation of CaMKII
0.0 2.4 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 0.4 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 2.8 REACTOME MHC CLASS II ANTIGEN PRESENTATION Genes involved in MHC class II antigen presentation
0.0 0.5 REACTOME PLATELET CALCIUM HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.0 1.0 REACTOME IL 2 SIGNALING Genes involved in Interleukin-2 signaling
0.0 0.5 REACTOME REGULATION OF IFNA SIGNALING Genes involved in Regulation of IFNA signaling
0.0 0.9 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0 0.2 REACTOME EICOSANOID LIGAND BINDING RECEPTORS Genes involved in Eicosanoid ligand-binding receptors
0.0 0.5 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0 1.3 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 0.6 REACTOME MEIOTIC SYNAPSIS Genes involved in Meiotic Synapsis
0.0 0.3 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.0 2.6 REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation