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GSE58827: Dynamics of the Mouse Liver

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Results for Meis2

Z-value: 0.80

Motif logo

Transcription factors associated with Meis2

Gene Symbol Gene ID Gene Info
ENSMUSG00000027210.21 Meis homeobox 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Meis2mm39_v1_chr2_-_115894993_1158950800.096.0e-01Click!

Activity profile of Meis2 motif

Sorted Z-values of Meis2 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr1_+_88139678 7.77 ENSMUST00000073049.7
UDP glucuronosyltransferase 1 family, polypeptide A1
chr8_+_105460627 6.06 ENSMUST00000034346.15
ENSMUST00000164182.3
carboxylesterase 2A
chr6_-_48549594 5.58 ENSMUST00000009425.7
ENSMUST00000204267.3
ENSMUST00000204930.3
ENSMUST00000204182.2
retinoic acid receptor responder (tazarotene induced) 2
chr13_-_63036096 5.27 ENSMUST00000092888.11
fructose bisphosphatase 1
chr7_+_119217004 5.06 ENSMUST00000047929.13
ENSMUST00000135683.3
acyl-CoA synthetase medium-chain family member 1
chr1_-_121255448 4.69 ENSMUST00000186915.2
ENSMUST00000160968.8
ENSMUST00000162582.2
insulin induced gene 2
chr8_-_94063823 4.64 ENSMUST00000044602.8
carboxylesterase 1G
chr1_-_121255400 4.42 ENSMUST00000159085.8
ENSMUST00000159125.2
ENSMUST00000161818.2
insulin induced gene 2
chr5_-_87485023 4.39 ENSMUST00000031195.3
UDP glucuronosyltransferase 2 family, polypeptide A3
chr5_+_137979763 4.38 ENSMUST00000035390.7
alpha-2-glycoprotein 1, zinc
chr8_-_118400418 4.34 ENSMUST00000173522.8
ENSMUST00000174450.2
short chain dehydrogenase/reductase family 42E, member 1
chr7_-_30643444 4.22 ENSMUST00000062620.9
hepcidin antimicrobial peptide
chr16_+_22769822 4.13 ENSMUST00000023590.9
histidine-rich glycoprotein
chr11_+_83637766 4.06 ENSMUST00000070832.3
WAP four-disulfide core domain 21
chr1_-_180023518 4.02 ENSMUST00000162769.8
ENSMUST00000161379.2
ENSMUST00000027766.13
ENSMUST00000161814.8
coenzyme Q8A
chr1_-_180023467 3.98 ENSMUST00000161746.2
ENSMUST00000160879.7
coenzyme Q8A
chr17_-_33136021 3.90 ENSMUST00000054174.9
cytochrome P450, family 4, subfamily f, polypeptide 14
chr6_-_85892586 3.73 ENSMUST00000174369.3
N-acetyltransferase 8 (GCN5-related) family member 1
chr17_-_56424577 3.59 ENSMUST00000019808.12
perilipin 5
chr16_+_22769844 3.59 ENSMUST00000232422.2
histidine-rich glycoprotein
chr9_+_106325828 3.53 ENSMUST00000217496.2
abhydrolase domain containing 14b
chr8_+_105573693 3.47 ENSMUST00000055052.6
carboxylesterase 2C
chr17_-_26309194 3.38 ENSMUST00000237265.2
ENSMUST00000236268.2
ENSMUST00000237875.2
ENSMUST00000150534.9
ENSMUST00000040907.8
2-4-dienoyl-Coenzyme A reductase 2, peroxisomal
chr11_-_4068779 3.38 ENSMUST00000003681.8
SEC14-like lipid binding 2
chr18_+_32064358 3.26 ENSMUST00000025254.9
LIM and senescent cell antigen like domains 2
chr9_-_71075939 3.21 ENSMUST00000113570.8
aquaporin 9
chr14_-_66246652 3.21 ENSMUST00000059970.9
gulonolactone (L-) oxidase
chr9_+_106325860 3.17 ENSMUST00000185527.3
abhydrolase domain containing 14b
chr8_+_107877252 3.08 ENSMUST00000034400.5
cytochrome b5 type B
chr7_-_126873219 3.04 ENSMUST00000082428.6
selenophosphate synthetase 2
chr15_+_4756684 3.04 ENSMUST00000161997.8
ENSMUST00000022788.15
complement component 6
chr7_+_25872836 3.02 ENSMUST00000082214.5
cytochrome P450, family 2, subfamily b, polypeptide 9
chr15_+_4756657 2.99 ENSMUST00000162585.8
complement component 6
chr8_-_118398264 2.91 ENSMUST00000037955.14
short chain dehydrogenase/reductase family 42E, member 1
chr19_-_8382424 2.83 ENSMUST00000064507.12
ENSMUST00000120540.2
ENSMUST00000096269.11
solute carrier family 22, member 30
chrX_+_59044796 2.80 ENSMUST00000033477.5
coagulation factor IX
chr10_+_23770586 2.80 ENSMUST00000041416.8
vanin 1
chr1_+_87983099 2.77 ENSMUST00000138182.8
ENSMUST00000113142.10
UDP glycosyltransferase 1 family, polypeptide A10
chr1_-_121255503 2.75 ENSMUST00000160688.2
insulin induced gene 2
chr17_-_32643067 2.74 ENSMUST00000237130.2
peptidoglycan recognition protein 2
chr12_-_81015479 2.73 ENSMUST00000218162.2
solute carrier family 10 (sodium/bile acid cotransporter family), member 1
chr2_-_27136826 2.72 ENSMUST00000149733.8
sarcosine dehydrogenase
chr6_-_106777014 2.66 ENSMUST00000013882.10
ENSMUST00000113239.10
cereblon
chr12_-_103956176 2.64 ENSMUST00000151709.3
ENSMUST00000176246.3
ENSMUST00000074693.13
ENSMUST00000120251.9
serine (or cysteine) peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 11
chr7_-_132178101 2.57 ENSMUST00000084500.8
ornithine aminotransferase
chr18_+_56565188 2.54 ENSMUST00000070166.6
GRAM domain containing 3
chr4_+_140966810 2.49 ENSMUST00000141834.9
Rho guanine nucleotide exchange factor (GEF) 19
chr3_-_107876477 2.47 ENSMUST00000004136.10
glutathione S-transferase, mu 3
chr15_+_10981833 2.44 ENSMUST00000070877.7
alpha-methylacyl-CoA racemase
chr16_-_22847808 2.40 ENSMUST00000115349.9
kininogen 2
chr16_-_22847760 2.39 ENSMUST00000039338.13
kininogen 2
chr16_+_22877000 2.38 ENSMUST00000039492.14
ENSMUST00000023589.15
ENSMUST00000089902.8
kininogen 1
chr16_-_22847829 2.31 ENSMUST00000100046.9
kininogen 2
chr15_+_7159038 2.29 ENSMUST00000067190.12
ENSMUST00000164529.9
LIF receptor alpha
chr15_+_82439273 2.29 ENSMUST00000229103.2
ENSMUST00000068861.8
ENSMUST00000229904.2
cytochrome P450, family 2, subfamily d, polypeptide 12
chr15_+_88703786 2.28 ENSMUST00000024042.5
cysteine-rich with EGF-like domains 2
chr15_-_60793115 2.20 ENSMUST00000096418.5
alpha-1-B glycoprotein
chr10_-_115198093 2.11 ENSMUST00000219890.2
ENSMUST00000218731.2
ENSMUST00000217887.2
ENSMUST00000092170.7
transmembrane protein 19
chr2_+_71811526 2.10 ENSMUST00000090826.12
ENSMUST00000102698.10
Rap guanine nucleotide exchange factor (GEF) 4
chr6_-_41012435 2.08 ENSMUST00000031931.6
RIKEN cDNA 2210010C04 gene
chr13_+_114954741 2.00 ENSMUST00000166104.9
ENSMUST00000166176.9
ENSMUST00000184335.8
ENSMUST00000184245.8
ENSMUST00000015680.11
ENSMUST00000184214.8
ENSMUST00000165022.9
ENSMUST00000164737.8
ENSMUST00000184781.8
ENSMUST00000183407.2
ENSMUST00000184672.8
molybdenum cofactor synthesis 2
chr2_+_27599259 1.98 ENSMUST00000100251.9
retinoid X receptor alpha
chr9_-_103099262 1.91 ENSMUST00000170904.2
transferrin
chr10_-_89342493 1.89 ENSMUST00000058126.15
ENSMUST00000105296.9
nuclear receptor subfamily 1, group H, member 4
chr11_-_51579441 1.80 ENSMUST00000007921.9
RIKEN cDNA 0610009B22 gene
chr2_-_30095805 1.78 ENSMUST00000113663.9
ENSMUST00000044038.10
kynurenine aminotransferase 1
chr16_-_22848153 1.76 ENSMUST00000232459.2
kininogen 2
chr15_-_82278223 1.76 ENSMUST00000170255.2
cytochrome P450, family 2, subfamily d, polypeptide 11
chr17_+_35482063 1.71 ENSMUST00000172503.3
histocompatibility 2, D region locus 1
chr5_+_121798932 1.70 ENSMUST00000111765.8
BRCA1 associated protein
chr2_+_43445359 1.69 ENSMUST00000050511.7
kynureninase
chr6_-_113412708 1.68 ENSMUST00000032416.11
ENSMUST00000113089.8
cell death-inducing DFFA-like effector c
chr2_-_30095784 1.67 ENSMUST00000113662.8
kynurenine aminotransferase 1
chr10_-_115197775 1.67 ENSMUST00000217848.2
transmembrane protein 19
chr1_+_9618173 1.66 ENSMUST00000144177.8
alcohol dehydrogenase, iron containing, 1
chr6_-_71239216 1.63 ENSMUST00000129630.3
ENSMUST00000114186.9
ENSMUST00000074301.10
SET and MYND domain containing 1
chr6_+_54016543 1.62 ENSMUST00000046856.14
chimerin 2
chr1_-_184578057 1.57 ENSMUST00000068725.10
mitochondrial amidoxime reducing component 2
chr1_+_87983189 1.55 ENSMUST00000173325.2
UDP glycosyltransferase 1 family, polypeptide A10
chr5_-_87402659 1.55 ENSMUST00000075858.4
UDP glucuronosyltransferase 2 family, polypeptide B37
chr16_+_13721016 1.54 ENSMUST00000128757.8
Mpv17 transgene, kidney disease mutant-like
chr5_+_114313940 1.52 ENSMUST00000146841.2
acetyl-Coenzyme A carboxylase beta
chr14_-_30645503 1.49 ENSMUST00000227995.2
inter-alpha trypsin inhibitor, heavy chain 3
chr2_-_25351024 1.46 ENSMUST00000151239.2
non-homologous end joining factor
chr6_-_113396271 1.45 ENSMUST00000147726.8
ENSMUST00000151618.8
ENSMUST00000060634.14
ENSMUST00000129047.8
ENSMUST00000129560.2
ENSMUST00000113092.9
RNA pseudouridylate synthase domain containing 3
chr16_-_37681508 1.43 ENSMUST00000205931.2
predicted gene, 36028
chr3_-_89294430 1.42 ENSMUST00000107433.8
zinc finger and BTB domain containing 7B
chr10_+_40505985 1.41 ENSMUST00000019977.8
ENSMUST00000214102.2
ENSMUST00000213503.2
ENSMUST00000213442.2
ENSMUST00000216830.2
D-aspartate oxidase
chr9_-_106124917 1.41 ENSMUST00000112524.9
ENSMUST00000219129.2
aminolevulinic acid synthase 1
chr19_-_7943365 1.40 ENSMUST00000182102.8
ENSMUST00000075619.5
solute carrier family 22, member 27
chr6_-_124613044 1.40 ENSMUST00000068797.3
ENSMUST00000218020.2
complement component 1, s subcomponent 2
chr7_+_44499818 1.39 ENSMUST00000136232.2
ENSMUST00000207223.2
AKT1 substrate 1 (proline-rich)
chr19_-_8109346 1.39 ENSMUST00000065651.5
solute carrier family 22, member 28
chr9_-_71678814 1.39 ENSMUST00000122065.2
ENSMUST00000121322.8
ENSMUST00000072899.9
cingulin-like 1
chr13_+_64309675 1.38 ENSMUST00000021929.10
hyaluronic acid binding protein 4
chr4_-_147989137 1.36 ENSMUST00000105716.9
ENSMUST00000105715.8
ENSMUST00000105714.8
ENSMUST00000030884.10
mitofusin 2
chr8_+_56747613 1.34 ENSMUST00000034026.10
hydroxyprostaglandin dehydrogenase 15 (NAD)
chr9_-_106125055 1.34 ENSMUST00000074082.13
aminolevulinic acid synthase 1
chr4_+_19575128 1.33 ENSMUST00000108253.8
ENSMUST00000029888.4
regulator of microtubule dynamics 1
chr11_-_120508713 1.32 ENSMUST00000106188.4
ENSMUST00000026129.16
phosphate cytidylyltransferase 2, ethanolamine
chr1_-_52766615 1.31 ENSMUST00000156876.8
ENSMUST00000087701.4
major facilitator superfamily domain containing 6
chr2_+_132688558 1.27 ENSMUST00000028835.13
ENSMUST00000110122.10
cardiolipin synthase 1
chr13_-_56696222 1.26 ENSMUST00000225183.2
leukocyte cell-derived chemotaxin 2
chr6_-_33037107 1.23 ENSMUST00000115091.2
ENSMUST00000127666.8
coiled-coil-helix-coiled-coil-helix domain containing 3
chr17_+_25798059 1.20 ENSMUST00000141606.3
ENSMUST00000063344.15
ENSMUST00000116641.9
lipase maturation factor 1
chrX_+_7588505 1.19 ENSMUST00000207675.2
ENSMUST00000116633.9
ENSMUST00000208996.2
ENSMUST00000144148.4
ENSMUST00000125991.9
ENSMUST00000148624.8
WD repeat domain 45
chr6_-_68609426 1.19 ENSMUST00000103328.3
immunoglobulin kappa variable 10-96
chrX_+_7588453 1.19 ENSMUST00000043045.10
ENSMUST00000207386.2
ENSMUST00000116634.9
ENSMUST00000208072.2
ENSMUST00000207589.2
ENSMUST00000208618.2
ENSMUST00000208443.2
ENSMUST00000207541.2
ENSMUST00000208528.2
ENSMUST00000115689.10
ENSMUST00000131077.9
ENSMUST00000115688.8
ENSMUST00000208156.2
WD repeat domain 45
predicted gene 45208
chr16_-_11727262 1.17 ENSMUST00000127972.8
ENSMUST00000121750.2
ENSMUST00000096272.11
ENSMUST00000073371.7
calcineurin-like phosphoesterase domain containing 1
chr10_+_107107477 1.16 ENSMUST00000020057.16
lin-7 homolog A (C. elegans)
chr9_-_66882669 1.16 ENSMUST00000215172.2
ENSMUST00000034929.7
lactamase, beta
chr10_-_18110682 1.14 ENSMUST00000052648.9
ENSMUST00000080860.13
ENSMUST00000173243.8
coiled-coil domain containing 28A
chr1_-_184615415 1.14 ENSMUST00000048308.6
RIKEN cDNA C130074G19 gene
chr3_+_107137924 1.13 ENSMUST00000179399.3
RIKEN cDNA A630076J17 gene
chr2_+_120807498 1.12 ENSMUST00000067582.14
transmembrane protein 62
chr7_-_126183392 1.11 ENSMUST00000128970.8
ENSMUST00000116269.9
ceroid lipofuscinosis, neuronal 3, juvenile (Batten, Spielmeyer-Vogt disease)
chr8_-_41494890 1.08 ENSMUST00000051379.14
mitochondrial tumor suppressor 1
chr5_+_31205971 1.06 ENSMUST00000013766.13
ENSMUST00000201773.4
ENSMUST00000200748.4
ENSMUST00000201136.2
all-trans retinoic acid induced differentiation factor
chr6_-_108162513 1.04 ENSMUST00000167338.8
ENSMUST00000172188.2
ENSMUST00000032191.16
sulfatase modifying factor 1
chr8_-_45747883 1.03 ENSMUST00000026907.6
kallikrein B, plasma 1
chr6_-_83654789 1.03 ENSMUST00000037882.8
CD207 antigen
chr13_+_24511387 1.01 ENSMUST00000224953.2
ENSMUST00000050859.13
ENSMUST00000167746.8
ENSMUST00000224819.2
cytidine monophospho-N-acetylneuraminic acid hydroxylase
chr4_+_59581557 1.01 ENSMUST00000030078.12
hydroxysteroid dehydrogenase like 2
chr6_-_33037191 1.00 ENSMUST00000066379.11
coiled-coil-helix-coiled-coil-helix domain containing 3
chr11_-_83469446 0.99 ENSMUST00000019266.6
chemokine (C-C motif) ligand 9
chr8_-_3767547 0.98 ENSMUST00000058040.7
C-type lectin domain family 4, member g
chr8_+_71823951 0.97 ENSMUST00000002469.9
ENSMUST00000110052.2
occludin/ELL domain containing 1
chr10_+_107107558 0.97 ENSMUST00000105280.5
lin-7 homolog A (C. elegans)
chr5_-_36987917 0.97 ENSMUST00000031002.10
mannosidase 2, alpha B2
chr17_-_57024660 0.92 ENSMUST00000164907.3
ENSMUST00000233208.2
vimentin-type intermediate filament associated coiled-coil protein
chr4_+_100336003 0.91 ENSMUST00000133493.9
ENSMUST00000092730.5
ubiquitin-conjugating enzyme E2U (putative)
chr2_+_68966125 0.90 ENSMUST00000041865.8
nitric oxide synthase trafficker
chr7_-_90125178 0.88 ENSMUST00000032843.9
transmembrane protein 126B
chr11_-_113456568 0.87 ENSMUST00000071539.10
ENSMUST00000106633.10
ENSMUST00000042657.16
ENSMUST00000149034.8
solute carrier family 39 (metal ion transporter), member 11
chr4_+_59581617 0.86 ENSMUST00000107528.8
hydroxysteroid dehydrogenase like 2
chr6_-_41423004 0.86 ENSMUST00000095999.7
predicted gene 10334
chr8_+_111573646 0.81 ENSMUST00000172668.8
ENSMUST00000034203.17
ENSMUST00000174398.8
component of oligomeric golgi complex 4
chr4_+_104770653 0.80 ENSMUST00000106803.9
ENSMUST00000106804.2
FYN binding protein 2
chrX_-_154121454 0.80 ENSMUST00000026328.11
peroxiredoxin 4
chr14_-_70585874 0.79 ENSMUST00000152067.8
solute carrier family 39 (zinc transporter), member 14
chr11_-_20781009 0.78 ENSMUST00000047028.9
lectin, galactoside binding-like
chr8_-_110464345 0.78 ENSMUST00000212605.2
ENSMUST00000093162.4
ENSMUST00000212726.2
ataxin 1-like
chr13_+_25029088 0.78 ENSMUST00000006893.9
RIKEN cDNA D130043K22 gene
chr2_+_30156523 0.77 ENSMUST00000091132.13
phytanoyl-CoA dioxygenase domain containing 1
chr9_+_107419416 0.77 ENSMUST00000010201.9
NPR2 like, GATOR1 complex subunit
chr3_+_81906768 0.76 ENSMUST00000107736.2
acid-sensing (proton-gated) ion channel family member 5
chr7_+_105203559 0.76 ENSMUST00000046983.10
sphingomyelin phosphodiesterase 1, acid lysosomal
chr14_+_6220581 0.76 ENSMUST00000112624.3
3-oxoacyl-ACP synthase, mitochondrial
chr8_-_107007596 0.76 ENSMUST00000212896.2
sphingomyelin phosphodiesterase 3, neutral
chr11_+_5470968 0.75 ENSMUST00000239150.2
X-box binding protein 1
chr13_+_47347301 0.75 ENSMUST00000110111.4
ring finger protein 144B
chr9_+_37466989 0.75 ENSMUST00000213126.2
sialic acid acetylesterase
chr8_+_105688344 0.74 ENSMUST00000043183.8
carboxylesterase 2G
chr3_-_116388334 0.73 ENSMUST00000197190.5
ENSMUST00000198454.2
tRNA methyltransferase 13
chr15_-_76608009 0.73 ENSMUST00000036247.10
RIKEN cDNA C030006K11 gene
chr2_-_102903680 0.73 ENSMUST00000132449.8
ENSMUST00000111183.2
ENSMUST00000011058.9
pyruvate dehydrogenase complex, component X
chr17_-_71158184 0.73 ENSMUST00000059775.15
TGFB-induced factor homeobox 1
chrX_+_141011695 0.72 ENSMUST00000112913.2
nuclear transport factor 2-like export factor 2
chr5_+_105879914 0.72 ENSMUST00000154807.2
leucine rich repeat containing 8D
chr8_+_70243813 0.72 ENSMUST00000034326.7
ATPase type 13A1
chr3_-_146518706 0.72 ENSMUST00000102515.10
protein kinase, cAMP dependent, catalytic, beta
chr11_+_77409392 0.70 ENSMUST00000147386.2
abhydrolase domain containing 15
chr16_+_87151073 0.70 ENSMUST00000054442.11
ENSMUST00000118310.8
ENSMUST00000120284.8
ENSMUST00000118115.2
N-6 adenine-specific DNA methyltransferase 1 (putative)
chr9_-_58448224 0.69 ENSMUST00000039788.11
CD276 antigen
chr3_+_85481416 0.69 ENSMUST00000107672.8
ENSMUST00000127348.8
ENSMUST00000107674.2
glutamyl-tRNA(Gln) amidotransferase, subunit B
chr10_+_60120259 0.68 ENSMUST00000165878.2
prosaposin
chr16_+_22710785 0.68 ENSMUST00000023583.7
ENSMUST00000232098.2
alpha-2-HS-glycoprotein
chr17_+_14499793 0.66 ENSMUST00000233344.2
ENSMUST00000232923.2
SPARC related modular calcium binding 2
chr1_+_87501721 0.66 ENSMUST00000166259.8
ENSMUST00000172222.8
ENSMUST00000163606.8
neuraminidase 2
chr5_-_52827015 0.66 ENSMUST00000031069.13
Sep (O-phosphoserine) tRNA:Sec (selenocysteine) tRNA synthase
chr7_-_126183716 0.65 ENSMUST00000150311.8
ceroid lipofuscinosis, neuronal 3, juvenile (Batten, Spielmeyer-Vogt disease)
chr4_+_156077834 0.65 ENSMUST00000105578.2
stromal cell derived factor 4
chr3_-_53771185 0.63 ENSMUST00000122330.2
ENSMUST00000146598.8
ubiquitin-fold modifier 1
chr2_-_101479846 0.63 ENSMUST00000078494.6
ENSMUST00000160722.8
ENSMUST00000160037.8
recombination activating 1
intraflagellar transport associated protein
chr8_-_62355690 0.61 ENSMUST00000121785.9
ENSMUST00000034057.14
palladin, cytoskeletal associated protein
chr9_-_107419309 0.61 ENSMUST00000195235.6
cytochrome b-561 domain containing 2
chr4_+_41465134 0.60 ENSMUST00000030154.7
nudix (nucleoside diphosphate linked moiety X)-type motif 2
chr5_+_67418137 0.60 ENSMUST00000161369.3
transmembrane protein 33
chr8_+_71823930 0.60 ENSMUST00000110051.2
occludin/ELL domain containing 1
chrX_-_50889955 0.59 ENSMUST00000069509.4
ENSMUST00000114869.8
ubiquitin specific peptidase 26
chr16_-_13720915 0.59 ENSMUST00000115803.9
pyridoxal-dependent decarboxylase domain containing 1
chr4_-_138641225 0.57 ENSMUST00000097830.4
OTU domain containing 3
chr16_-_13720949 0.57 ENSMUST00000023361.12
ENSMUST00000115802.2
pyridoxal-dependent decarboxylase domain containing 1
chr2_+_32489710 0.57 ENSMUST00000131229.8
ENSMUST00000140983.8
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6
chr17_-_36369263 0.57 ENSMUST00000113742.3
predicted gene 11127
chr17_-_30845845 0.57 ENSMUST00000235547.2
ENSMUST00000188852.2
glyoxalase 1
RIKEN cDNA 1700097N02 gene
chr3_+_135191366 0.57 ENSMUST00000029814.10
mannosidase, beta A, lysosomal
chr9_+_32027335 0.57 ENSMUST00000174641.8
Rho GTPase activating protein 32
chr13_+_46822992 0.56 ENSMUST00000099547.4
family with sequence similarity 8, member A1
chr11_+_51152546 0.56 ENSMUST00000130641.8
CDC like kinase 4
chr7_+_125307060 0.56 ENSMUST00000124223.8
ENSMUST00000069660.13
katanin interacting protein
chr7_-_45362867 0.56 ENSMUST00000211340.2
sphingosine kinase 2
chr17_+_14499768 0.56 ENSMUST00000024660.9
SPARC related modular calcium binding 2
chr2_+_91090167 0.55 ENSMUST00000138470.2
protein kinase C and casein kinase substrate in neurons 3
chr16_-_18904240 0.54 ENSMUST00000103746.3
immunoglobulin lambda variable 1
chr8_-_3329605 0.54 ENSMUST00000091291.5
insulin receptor
chr19_+_11943265 0.54 ENSMUST00000025590.11
oxysterol binding protein
chr1_-_182169150 0.53 ENSMUST00000051431.10
F-box protein 28
chr7_+_141503719 0.53 ENSMUST00000105989.9
ENSMUST00000075528.12
ENSMUST00000174499.8
BR serine/threonine kinase 2
chr9_+_122980006 0.53 ENSMUST00000026890.6
C-type lectin domain family 3, member b

Network of associatons between targets according to the STRING database.

First level regulatory network of Meis2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
2.6 7.8 GO:0018879 biphenyl metabolic process(GO:0018879)
2.6 7.7 GO:0097037 heme export(GO:0097037)
1.5 4.6 GO:0090320 chylomicron assembly(GO:0034378) regulation of chylomicron remnant clearance(GO:0090320)
1.5 6.0 GO:0001970 positive regulation of activation of membrane attack complex(GO:0001970)
1.3 5.3 GO:0046351 disaccharide biosynthetic process(GO:0046351)
1.2 3.7 GO:0018003 peptidyl-lysine N6-acetylation(GO:0018003)
1.2 3.5 GO:0097052 L-kynurenine metabolic process(GO:0097052)
1.1 4.2 GO:0034757 negative regulation of iron ion transport(GO:0034757) negative regulation of iron ion transmembrane transport(GO:0034760)
0.9 5.6 GO:0061760 antifungal innate immune response(GO:0061760)
0.9 2.7 GO:1901053 sarcosine metabolic process(GO:1901052) sarcosine catabolic process(GO:1901053)
0.8 3.2 GO:0015855 nucleobase transport(GO:0015851) pyrimidine nucleobase transport(GO:0015855)
0.7 3.6 GO:0035359 negative regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035359)
0.7 11.9 GO:0060363 cranial suture morphogenesis(GO:0060363)
0.6 3.2 GO:0019853 L-ascorbic acid biosynthetic process(GO:0019853)
0.6 8.7 GO:0019585 uronic acid metabolic process(GO:0006063) glucuronate metabolic process(GO:0019585) cellular glucuronidation(GO:0052695)
0.6 1.7 GO:0019442 tryptophan catabolic process to acetyl-CoA(GO:0019442)
0.5 1.5 GO:0046949 fatty-acyl-CoA biosynthetic process(GO:0046949) malonyl-CoA metabolic process(GO:2001293)
0.5 1.9 GO:0038183 histone H3-R17 methylation(GO:0034971) bile acid signaling pathway(GO:0038183)
0.5 1.4 GO:0006533 aspartate catabolic process(GO:0006533)
0.5 2.7 GO:0032827 peptidoglycan metabolic process(GO:0000270) peptidoglycan catabolic process(GO:0009253) negative regulation of natural killer cell differentiation(GO:0032824) negative regulation of natural killer cell differentiation involved in immune response(GO:0032827)
0.4 3.0 GO:0016259 selenocysteine metabolic process(GO:0016259)
0.4 2.1 GO:1904457 positive regulation of neuronal action potential(GO:1904457)
0.4 2.0 GO:0045994 regulation of translational initiation by iron(GO:0006447) positive regulation of translational initiation by iron(GO:0045994)
0.4 5.6 GO:0015747 urate transport(GO:0015747)
0.4 2.1 GO:1903361 protein localization to basolateral plasma membrane(GO:1903361)
0.4 1.4 GO:0043376 regulation of CD8-positive, alpha-beta T cell differentiation(GO:0043376)
0.4 1.8 GO:0035752 lysosomal lumen pH elevation(GO:0035752)
0.3 8.3 GO:0006744 ubiquinone biosynthetic process(GO:0006744)
0.3 1.7 GO:0002484 antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway(GO:0002484) antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent(GO:0002485)
0.3 0.3 GO:0007521 muscle cell fate determination(GO:0007521)
0.3 2.3 GO:0048861 oncostatin-M-mediated signaling pathway(GO:0038165) leukemia inhibitory factor signaling pathway(GO:0048861)
0.3 2.6 GO:0034214 protein hexamerization(GO:0034214)
0.3 0.8 GO:0070681 glutaminyl-tRNAGln biosynthesis via transamidation(GO:0070681)
0.3 1.5 GO:0010730 negative regulation of hydrogen peroxide biosynthetic process(GO:0010730)
0.3 1.0 GO:0046381 CMP-N-acetylneuraminate metabolic process(GO:0046381)
0.3 0.8 GO:1903487 regulation of lactation(GO:1903487)
0.2 2.0 GO:0006777 Mo-molybdopterin cofactor biosynthetic process(GO:0006777) Mo-molybdopterin cofactor metabolic process(GO:0019720)
0.2 1.9 GO:0070447 positive regulation of oligodendrocyte progenitor proliferation(GO:0070447)
0.2 0.7 GO:0046168 glycerol-3-phosphate catabolic process(GO:0046168)
0.2 4.3 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.2 2.4 GO:2000346 negative regulation of hepatocyte proliferation(GO:2000346)
0.2 1.0 GO:0051919 positive regulation of fibrinolysis(GO:0051919)
0.2 0.4 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.2 0.6 GO:1903896 positive regulation of IRE1-mediated unfolded protein response(GO:1903896)
0.2 1.2 GO:0034382 chylomicron remnant clearance(GO:0034382) triglyceride-rich lipoprotein particle clearance(GO:0071830)
0.2 3.7 GO:0034497 protein localization to pre-autophagosomal structure(GO:0034497)
0.2 0.6 GO:1990167 protein K27-linked deubiquitination(GO:1990167)
0.2 11.2 GO:1900047 negative regulation of blood coagulation(GO:0030195) negative regulation of hemostasis(GO:1900047)
0.2 0.8 GO:0090154 positive regulation of sphingolipid biosynthetic process(GO:0090154) positive regulation of ceramide biosynthetic process(GO:2000304)
0.2 2.4 GO:0008300 isoprenoid catabolic process(GO:0008300)
0.2 0.5 GO:1990535 neuron projection maintenance(GO:1990535)
0.2 0.7 GO:0045077 negative regulation of interferon-gamma biosynthetic process(GO:0045077)
0.2 3.4 GO:0090205 positive regulation of cholesterol biosynthetic process(GO:0045542) positive regulation of cholesterol metabolic process(GO:0090205)
0.2 0.8 GO:0022417 protein maturation by protein folding(GO:0022417)
0.2 2.8 GO:2000400 positive regulation of T cell differentiation in thymus(GO:0033089) positive regulation of thymocyte aggregation(GO:2000400)
0.1 11.0 GO:0019369 arachidonic acid metabolic process(GO:0019369)
0.1 0.6 GO:1902309 negative regulation of peptidyl-serine dephosphorylation(GO:1902309)
0.1 1.5 GO:0031119 tRNA pseudouridine synthesis(GO:0031119)
0.1 0.6 GO:0006669 sphinganine-1-phosphate biosynthetic process(GO:0006669)
0.1 2.2 GO:0042407 cristae formation(GO:0042407)
0.1 4.1 GO:0050872 white fat cell differentiation(GO:0050872)
0.1 1.4 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.1 0.6 GO:1990592 protein polyufmylation(GO:1990564) protein K69-linked ufmylation(GO:1990592)
0.1 0.6 GO:0002331 pre-B cell allelic exclusion(GO:0002331)
0.1 0.8 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.1 0.7 GO:0070895 transposon integration(GO:0070893) regulation of transposon integration(GO:0070894) negative regulation of transposon integration(GO:0070895)
0.1 0.5 GO:0042723 thiamine metabolic process(GO:0006772) thiamine-containing compound metabolic process(GO:0042723) regulation of adenosine receptor signaling pathway(GO:0060167) positive regulation of adenosine receptor signaling pathway(GO:0060168)
0.1 0.8 GO:1902035 positive regulation of hematopoietic stem cell proliferation(GO:1902035)
0.1 0.8 GO:0051792 medium-chain fatty acid biosynthetic process(GO:0051792)
0.1 2.7 GO:0090073 positive regulation of protein homodimerization activity(GO:0090073)
0.1 1.3 GO:0007567 parturition(GO:0007567)
0.1 0.3 GO:1903251 multi-ciliated epithelial cell differentiation(GO:1903251)
0.1 0.4 GO:0070625 zymogen granule exocytosis(GO:0070625)
0.1 1.5 GO:0051103 DNA ligation involved in DNA repair(GO:0051103)
0.1 0.7 GO:0061732 mitochondrial acetyl-CoA biosynthetic process from pyruvate(GO:0061732)
0.1 2.7 GO:0015721 bile acid and bile salt transport(GO:0015721)
0.1 1.0 GO:0006013 mannose metabolic process(GO:0006013)
0.1 0.3 GO:0033615 mitochondrial proton-transporting ATP synthase complex assembly(GO:0033615)
0.1 0.7 GO:0006689 ganglioside catabolic process(GO:0006689) oligosaccharide catabolic process(GO:0009313)
0.1 0.4 GO:0035694 mitochondrial protein catabolic process(GO:0035694)
0.1 3.7 GO:0006636 unsaturated fatty acid biosynthetic process(GO:0006636)
0.1 0.5 GO:0097343 ripoptosome assembly(GO:0097343) ripoptosome assembly involved in necroptotic process(GO:1901026)
0.1 0.5 GO:0010756 positive regulation of plasminogen activation(GO:0010756)
0.1 1.7 GO:0034389 lipid particle organization(GO:0034389)
0.1 0.2 GO:0002380 immunoglobulin secretion involved in immune response(GO:0002380)
0.1 0.7 GO:0006451 selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)
0.1 0.5 GO:0031038 myosin II filament organization(GO:0031038) regulation of myosin II filament organization(GO:0043519)
0.1 2.9 GO:0030212 hyaluronan metabolic process(GO:0030212)
0.1 0.2 GO:0042138 meiotic DNA double-strand break formation(GO:0042138)
0.1 0.2 GO:0000715 nucleotide-excision repair, DNA damage recognition(GO:0000715)
0.1 0.8 GO:0048280 vesicle fusion with Golgi apparatus(GO:0048280)
0.1 1.4 GO:0045792 negative regulation of cell size(GO:0045792)
0.1 5.1 GO:0035383 acyl-CoA metabolic process(GO:0006637) thioester metabolic process(GO:0035383)
0.1 0.6 GO:1990118 sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.1 0.5 GO:2000643 positive regulation of early endosome to late endosome transport(GO:2000643)
0.1 0.6 GO:0051596 methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione(GO:0019243) methylglyoxal catabolic process(GO:0051596) methylglyoxal catabolic process to lactate(GO:0061727)
0.1 0.4 GO:1903242 regulation of cardiac muscle adaptation(GO:0010612) regulation of cardiac muscle hypertrophy in response to stress(GO:1903242)
0.1 0.7 GO:1901621 negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:1901621)
0.1 0.2 GO:0060807 cardiogenic plate morphogenesis(GO:0003142) regulation of transcription from RNA polymerase II promoter involved in definitive endodermal cell fate specification(GO:0060807)
0.1 0.8 GO:0000301 retrograde transport, vesicle recycling within Golgi(GO:0000301)
0.1 0.4 GO:1900747 negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
0.1 0.6 GO:0033689 negative regulation of osteoblast proliferation(GO:0033689)
0.1 0.3 GO:0008616 queuosine biosynthetic process(GO:0008616) queuosine metabolic process(GO:0046116)
0.0 0.8 GO:0006995 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.0 0.2 GO:0032917 polyamine acetylation(GO:0032917) spermidine acetylation(GO:0032918)
0.0 0.6 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.0 0.2 GO:0002191 cap-dependent translational initiation(GO:0002191)
0.0 0.8 GO:0071578 zinc II ion transmembrane import(GO:0071578)
0.0 0.1 GO:0006478 peptidyl-tyrosine sulfation(GO:0006478)
0.0 0.2 GO:0003376 sphingosine-1-phosphate signaling pathway(GO:0003376)
0.0 0.7 GO:0060736 prostate gland growth(GO:0060736)
0.0 0.8 GO:0002710 negative regulation of T cell mediated immunity(GO:0002710)
0.0 0.4 GO:0010815 bradykinin catabolic process(GO:0010815)
0.0 0.6 GO:2000096 positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096)
0.0 0.7 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.0 1.6 GO:0045663 positive regulation of myoblast differentiation(GO:0045663)
0.0 0.4 GO:0006729 tetrahydrobiopterin biosynthetic process(GO:0006729)
0.0 7.5 GO:0006694 steroid biosynthetic process(GO:0006694)
0.0 2.8 GO:0035690 cellular response to drug(GO:0035690)
0.0 1.1 GO:0010758 regulation of macrophage chemotaxis(GO:0010758)
0.0 0.8 GO:0006516 glycoprotein catabolic process(GO:0006516)
0.0 0.2 GO:0010968 regulation of microtubule nucleation(GO:0010968)
0.0 1.2 GO:0046854 phosphatidylinositol phosphorylation(GO:0046854)
0.0 1.0 GO:0045662 negative regulation of myoblast differentiation(GO:0045662)
0.0 0.5 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.0 0.2 GO:0060332 positive regulation of response to interferon-gamma(GO:0060332) positive regulation of interferon-gamma-mediated signaling pathway(GO:0060335)
0.0 0.6 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.0 0.2 GO:0090166 positive regulation of protein glycosylation(GO:0060050) Golgi disassembly(GO:0090166) spindle assembly involved in meiosis(GO:0090306)
0.0 0.9 GO:0006829 zinc II ion transport(GO:0006829)
0.0 0.6 GO:0044406 adhesion of symbiont to host(GO:0044406)
0.0 0.3 GO:2000052 positive regulation of non-canonical Wnt signaling pathway(GO:2000052)
0.0 0.3 GO:0042637 catagen(GO:0042637)
0.0 0.4 GO:0043248 proteasome assembly(GO:0043248)
0.0 0.4 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.0 0.5 GO:0044126 regulation of growth of symbiont in host(GO:0044126)
0.0 0.6 GO:0003334 keratinocyte development(GO:0003334)
0.0 0.3 GO:0002719 negative regulation of cytokine production involved in immune response(GO:0002719)
0.0 0.3 GO:0018904 glycerol ether metabolic process(GO:0006662) ether metabolic process(GO:0018904)
0.0 0.4 GO:1901673 regulation of mitotic spindle assembly(GO:1901673)
0.0 0.7 GO:0030488 tRNA methylation(GO:0030488)
0.0 1.5 GO:0016574 histone ubiquitination(GO:0016574)
0.0 0.4 GO:1900119 positive regulation of execution phase of apoptosis(GO:1900119)
0.0 0.3 GO:0033234 negative regulation of protein sumoylation(GO:0033234)
0.0 5.2 GO:0006486 protein glycosylation(GO:0006486) macromolecule glycosylation(GO:0043413)
0.0 1.4 GO:0070059 intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress(GO:0070059)
0.0 0.2 GO:0006012 galactose metabolic process(GO:0006012)
0.0 0.0 GO:0032417 positive regulation of sodium:proton antiporter activity(GO:0032417)
0.0 0.2 GO:0007196 adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway(GO:0007196)
0.0 0.8 GO:2000171 negative regulation of dendrite development(GO:2000171)
0.0 0.3 GO:0097011 cellular response to granulocyte macrophage colony-stimulating factor stimulus(GO:0097011)
0.0 0.4 GO:0046321 positive regulation of fatty acid oxidation(GO:0046321)
0.0 0.0 GO:0070900 mitochondrial tRNA modification(GO:0070900) mitochondrial RNA modification(GO:1900864)
0.0 0.2 GO:0046007 negative regulation of activated T cell proliferation(GO:0046007)
0.0 0.7 GO:0046627 negative regulation of insulin receptor signaling pathway(GO:0046627)
0.0 0.1 GO:0006450 regulation of translational fidelity(GO:0006450)
0.0 0.4 GO:0000002 mitochondrial genome maintenance(GO:0000002)
0.0 0.1 GO:0030242 pexophagy(GO:0030242)
0.0 0.2 GO:0031581 hemidesmosome assembly(GO:0031581)
0.0 0.0 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
0.0 0.1 GO:0051095 regulation of helicase activity(GO:0051095) positive regulation of helicase activity(GO:0051096)
0.0 0.5 GO:0097031 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.0 0.1 GO:0034982 protein processing involved in protein targeting to mitochondrion(GO:0006627) mitochondrial protein processing(GO:0034982)
0.0 0.0 GO:0035521 monoubiquitinated histone deubiquitination(GO:0035521) monoubiquitinated histone H2A deubiquitination(GO:0035522)
0.0 0.4 GO:0042775 mitochondrial ATP synthesis coupled electron transport(GO:0042775)
0.0 0.2 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.0 3.1 GO:0001101 response to acid chemical(GO:0001101)
0.0 0.3 GO:0050962 detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962)
0.0 0.1 GO:1904262 negative regulation of TORC1 signaling(GO:1904262)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
2.6 7.7 GO:0061474 phagolysosome membrane(GO:0061474)
1.5 11.9 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.7 6.0 GO:0005579 membrane attack complex(GO:0005579)
0.7 2.0 GO:0019008 molybdopterin synthase complex(GO:0019008)
0.5 7.8 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.4 3.7 GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.4 1.8 GO:0044316 cone cell pedicle(GO:0044316)
0.3 2.2 GO:0061617 MICOS complex(GO:0061617)
0.3 0.8 GO:0030956 glutamyl-tRNA(Gln) amidotransferase complex(GO:0030956)
0.3 2.1 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)
0.2 1.5 GO:0043564 Ku70:Ku80 complex(GO:0043564)
0.2 1.5 GO:0033503 HULC complex(GO:0033503)
0.2 2.1 GO:0031464 Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.2 1.9 GO:0097433 dense body(GO:0097433)
0.2 0.6 GO:0031084 BLOC-2 complex(GO:0031084)
0.2 0.8 GO:1990130 Iml1 complex(GO:1990130)
0.1 0.7 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.1 2.4 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.1 1.4 GO:0031931 TORC1 complex(GO:0031931)
0.1 1.7 GO:0042612 MHC class I protein complex(GO:0042612)
0.1 0.5 GO:0098559 cytoplasmic side of early endosome membrane(GO:0098559)
0.1 0.7 GO:0045254 pyruvate dehydrogenase complex(GO:0045254)
0.1 0.5 GO:0005899 insulin receptor complex(GO:0005899)
0.1 0.3 GO:0002111 BRCA2-BRAF35 complex(GO:0002111)
0.1 0.9 GO:0045098 type III intermediate filament(GO:0045098)
0.1 20.1 GO:0072562 blood microparticle(GO:0072562)
0.1 0.5 GO:0001652 granular component(GO:0001652)
0.1 1.0 GO:0000137 Golgi cis cisterna(GO:0000137)
0.1 0.7 GO:0005796 Golgi lumen(GO:0005796)
0.1 0.2 GO:0000110 nucleotide-excision repair factor 1 complex(GO:0000110)
0.1 0.8 GO:0017119 Golgi transport complex(GO:0017119)
0.1 0.8 GO:0042599 lamellar body(GO:0042599)
0.0 5.2 GO:0005811 lipid particle(GO:0005811)
0.0 0.6 GO:0020005 symbiont-containing vacuole membrane(GO:0020005)
0.0 0.1 GO:0017071 intracellular cyclic nucleotide activated cation channel complex(GO:0017071)
0.0 1.4 GO:0031306 intrinsic component of mitochondrial outer membrane(GO:0031306)
0.0 0.6 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.0 0.2 GO:0034657 GID complex(GO:0034657)
0.0 1.2 GO:0005614 interstitial matrix(GO:0005614)
0.0 0.2 GO:0044308 axonal spine(GO:0044308)
0.0 0.2 GO:0035841 new growing cell tip(GO:0035841)
0.0 0.4 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
0.0 7.6 GO:0042579 peroxisome(GO:0005777) microbody(GO:0042579)
0.0 0.4 GO:0000815 ESCRT III complex(GO:0000815)
0.0 2.6 GO:0005795 Golgi stack(GO:0005795)
0.0 0.3 GO:0005883 neurofilament(GO:0005883)
0.0 0.3 GO:0090571 RNA polymerase II transcription repressor complex(GO:0090571)
0.0 0.1 GO:0034271 phosphatidylinositol 3-kinase complex, class III, type I(GO:0034271) phosphatidylinositol 3-kinase complex, class III, type II(GO:0034272)
0.0 1.2 GO:0030964 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 0.3 GO:0034464 BBSome(GO:0034464)
0.0 0.4 GO:0098644 complex of collagen trimers(GO:0098644)
0.0 0.2 GO:0070545 PeBoW complex(GO:0070545)
0.0 5.6 GO:0005759 mitochondrial matrix(GO:0005759)
0.0 0.4 GO:0098563 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.0 0.2 GO:0016528 sarcoplasm(GO:0016528)
0.0 1.3 GO:0016459 myosin complex(GO:0016459)
0.0 0.2 GO:0097542 ciliary tip(GO:0097542)
0.0 0.8 GO:0001772 immunological synapse(GO:0001772)
0.0 0.3 GO:0001891 phagocytic cup(GO:0001891)
0.0 25.7 GO:0005615 extracellular space(GO:0005615)
0.0 0.3 GO:0005922 connexon complex(GO:0005922)
0.0 1.7 GO:0097517 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0 3.3 GO:0016323 basolateral plasma membrane(GO:0016323)
0.0 4.6 GO:0005743 mitochondrial inner membrane(GO:0005743)
0.0 0.2 GO:0046581 intercellular canaliculus(GO:0046581)
0.0 0.2 GO:0045277 respiratory chain complex IV(GO:0045277)
0.0 15.2 GO:0005739 mitochondrion(GO:0005739)
0.0 22.5 GO:0005783 endoplasmic reticulum(GO:0005783)
0.0 1.9 GO:0098852 lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852)
0.0 0.1 GO:0000445 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 3.9 GO:0052871 tocopherol omega-hydroxylase activity(GO:0052870) alpha-tocopherol omega-hydroxylase activity(GO:0052871)
1.2 3.5 GO:0047312 L-phenylalanine:pyruvate aminotransferase activity(GO:0047312) glutamine-phenylpyruvate transaminase activity(GO:0047316) L-glutamine:pyruvate aminotransferase activity(GO:0047945)
1.0 3.0 GO:0004756 selenide, water dikinase activity(GO:0004756) phosphotransferase activity, paired acceptors(GO:0016781)
0.9 2.7 GO:0016749 5-aminolevulinate synthase activity(GO:0003870) N-succinyltransferase activity(GO:0016749)
0.9 2.7 GO:0008480 sarcosine dehydrogenase activity(GO:0008480)
0.8 3.4 GO:0019166 trans-2-enoyl-CoA reductase (NADPH) activity(GO:0019166)
0.6 3.2 GO:0005350 purine nucleobase transmembrane transporter activity(GO:0005345) pyrimidine nucleobase transmembrane transporter activity(GO:0005350) nucleobase transmembrane transporter activity(GO:0015205) glycerol channel activity(GO:0015254)
0.6 5.1 GO:0003996 acyl-CoA ligase activity(GO:0003996)
0.6 2.5 GO:0016899 oxidoreductase activity, acting on the CH-OH group of donors, oxygen as acceptor(GO:0016899)
0.5 2.3 GO:0004923 leukemia inhibitory factor receptor activity(GO:0004923)
0.5 2.7 GO:0008745 N-acetylmuramoyl-L-alanine amidase activity(GO:0008745) peptidoglycan receptor activity(GO:0016019)
0.5 7.2 GO:0003854 3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854)
0.4 18.0 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.4 1.7 GO:0016822 hydrolase activity, acting on acid carbon-carbon bonds(GO:0016822) hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances(GO:0016823)
0.4 1.9 GO:0038181 bile acid receptor activity(GO:0038181)
0.4 1.4 GO:0003884 D-amino-acid oxidase activity(GO:0003884)
0.3 2.8 GO:0034235 GPI anchor binding(GO:0034235)
0.3 2.7 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.3 3.7 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.3 1.0 GO:0030338 CMP-N-acetylneuraminate monooxygenase activity(GO:0030338)
0.3 5.6 GO:1901702 urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.3 5.3 GO:0050308 sugar-phosphatase activity(GO:0050308)
0.3 1.5 GO:0003989 acetyl-CoA carboxylase activity(GO:0003989)
0.3 2.1 GO:0097016 L27 domain binding(GO:0097016)
0.3 1.7 GO:0004022 alcohol dehydrogenase (NAD) activity(GO:0004022)
0.3 3.6 GO:0035473 lipase binding(GO:0035473)
0.3 1.9 GO:0015091 ferric iron transmembrane transporter activity(GO:0015091) trivalent inorganic cation transmembrane transporter activity(GO:0072510)
0.3 0.8 GO:0050567 glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity(GO:0050567)
0.3 1.0 GO:0004441 inositol-1,4-bisphosphate 1-phosphatase activity(GO:0004441)
0.2 2.0 GO:0004886 9-cis retinoic acid receptor activity(GO:0004886)
0.2 1.3 GO:0004957 prostaglandin E receptor activity(GO:0004957)
0.2 0.5 GO:0005009 insulin-activated receptor activity(GO:0005009)
0.2 19.6 GO:0004869 cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.2 1.5 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.2 0.8 GO:0004315 3-oxoacyl-[acyl-carrier-protein] synthase activity(GO:0004315)
0.2 0.5 GO:0052642 lysophosphatidic acid phosphatase activity(GO:0052642)
0.1 1.3 GO:0070567 cytidylyltransferase activity(GO:0070567)
0.1 0.7 GO:0034604 pyruvate dehydrogenase activity(GO:0004738) pyruvate dehydrogenase [NAD(P)+] activity(GO:0034603) pyruvate dehydrogenase (NAD+) activity(GO:0034604)
0.1 2.0 GO:0016783 sulfurtransferase activity(GO:0016783)
0.1 0.7 GO:0004367 glycerol-3-phosphate dehydrogenase [NAD+] activity(GO:0004367)
0.1 4.7 GO:0070330 aromatase activity(GO:0070330)
0.1 0.7 GO:0004308 exo-alpha-sialidase activity(GO:0004308) alpha-sialidase activity(GO:0016997) exo-alpha-(2->3)-sialidase activity(GO:0052794) exo-alpha-(2->6)-sialidase activity(GO:0052795) exo-alpha-(2->8)-sialidase activity(GO:0052796)
0.1 0.4 GO:0016838 carbon-oxygen lyase activity, acting on phosphates(GO:0016838)
0.1 1.7 GO:0030881 beta-2-microglobulin binding(GO:0030881)
0.1 2.4 GO:0016854 racemase and epimerase activity(GO:0016854)
0.1 0.8 GO:0015093 ferrous iron transmembrane transporter activity(GO:0015093)
0.1 5.4 GO:0043531 ADP binding(GO:0043531)
0.1 0.3 GO:0008113 peptide-methionine (S)-S-oxide reductase activity(GO:0008113)
0.1 1.1 GO:0005225 volume-sensitive anion channel activity(GO:0005225)
0.1 2.6 GO:0008483 transaminase activity(GO:0008483)
0.1 0.7 GO:0004565 beta-galactosidase activity(GO:0004565)
0.1 1.6 GO:0015923 mannosidase activity(GO:0015923)
0.1 0.4 GO:0043295 glutathione binding(GO:0043295) oligopeptide binding(GO:1900750)
0.1 14.7 GO:0052689 carboxylic ester hydrolase activity(GO:0052689)
0.1 0.6 GO:0015386 potassium:proton antiporter activity(GO:0015386)
0.1 0.3 GO:0016971 flavin-linked sulfhydryl oxidase activity(GO:0016971)
0.1 1.4 GO:0050321 tau-protein kinase activity(GO:0050321)
0.1 0.7 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.1 0.8 GO:0015280 ligand-gated sodium channel activity(GO:0015280)
0.1 0.6 GO:0008481 sphinganine kinase activity(GO:0008481) D-erythro-sphingosine kinase activity(GO:0017050)
0.1 0.5 GO:0046974 histone methyltransferase activity (H3-K9 specific)(GO:0046974)
0.1 0.2 GO:0033858 N-acetylgalactosamine kinase activity(GO:0033858)
0.1 0.5 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.1 0.5 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.1 0.2 GO:0019809 spermidine binding(GO:0019809)
0.1 1.4 GO:0005540 hyaluronic acid binding(GO:0005540)
0.1 1.0 GO:0019215 intermediate filament binding(GO:0019215)
0.0 1.9 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.0 2.1 GO:0008395 steroid hydroxylase activity(GO:0008395)
0.0 0.5 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.0 0.8 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.0 0.4 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.0 1.7 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.0 3.5 GO:0005507 copper ion binding(GO:0005507)
0.0 2.4 GO:0004364 glutathione transferase activity(GO:0004364)
0.0 0.8 GO:0051920 peroxiredoxin activity(GO:0051920)
0.0 0.1 GO:0008476 protein-tyrosine sulfotransferase activity(GO:0008476)
0.0 0.2 GO:0038036 sphingosine-1-phosphate receptor activity(GO:0038036)
0.0 0.4 GO:0031433 telethonin binding(GO:0031433)
0.0 1.9 GO:0030552 cAMP binding(GO:0030552)
0.0 0.3 GO:0008479 queuine tRNA-ribosyltransferase activity(GO:0008479)
0.0 0.3 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.0 7.7 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 0.6 GO:0019855 calcium channel inhibitor activity(GO:0019855)
0.0 0.9 GO:0005351 sugar:proton symporter activity(GO:0005351)
0.0 5.4 GO:0030414 peptidase inhibitor activity(GO:0030414)
0.0 0.7 GO:0008432 JUN kinase binding(GO:0008432)
0.0 0.5 GO:0043522 leucine zipper domain binding(GO:0043522)
0.0 0.6 GO:0004551 nucleotide diphosphatase activity(GO:0004551)
0.0 0.8 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
0.0 0.2 GO:0046976 histone methyltransferase activity (H3-K27 specific)(GO:0046976)
0.0 0.1 GO:0005143 interleukin-12 receptor binding(GO:0005143)
0.0 0.6 GO:0042605 peptide antigen binding(GO:0042605)
0.0 0.7 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.0 3.7 GO:0032947 protein complex scaffold(GO:0032947)
0.0 0.2 GO:0061676 importin-alpha family protein binding(GO:0061676)
0.0 0.2 GO:0001642 group III metabotropic glutamate receptor activity(GO:0001642)
0.0 0.3 GO:0022889 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.0 0.9 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 1.0 GO:0008009 chemokine activity(GO:0008009)
0.0 0.2 GO:0004111 creatine kinase activity(GO:0004111)
0.0 0.5 GO:0070273 phosphatidylinositol-4-phosphate binding(GO:0070273)
0.0 0.1 GO:0009918 sterol delta7 reductase activity(GO:0009918) 7-dehydrocholesterol reductase activity(GO:0047598)
0.0 0.2 GO:0071074 eukaryotic initiation factor eIF2 binding(GO:0071074)
0.0 1.8 GO:0020037 heme binding(GO:0020037)
0.0 0.4 GO:0031702 type 1 angiotensin receptor binding(GO:0031702)
0.0 0.1 GO:0016846 carbon-sulfur lyase activity(GO:0016846)
0.0 0.8 GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups(GO:0016765)
0.0 0.1 GO:0098519 nucleotide phosphatase activity, acting on free nucleotides(GO:0098519)
0.0 0.3 GO:0005243 gap junction channel activity(GO:0005243)
0.0 0.3 GO:0000400 four-way junction DNA binding(GO:0000400)
0.0 0.8 GO:0018024 histone-lysine N-methyltransferase activity(GO:0018024)
0.0 0.5 GO:0008137 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 0.7 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.0 0.4 GO:0031005 filamin binding(GO:0031005)
0.0 0.2 GO:0003956 NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956)
0.0 0.8 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 0.7 GO:0008276 protein methyltransferase activity(GO:0008276)
0.0 0.4 GO:0017166 vinculin binding(GO:0017166)
0.0 0.1 GO:0008502 melatonin receptor activity(GO:0008502)
0.0 0.6 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.4 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.1 3.9 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.1 0.2 PID S1P S1P2 PATHWAY S1P2 pathway
0.1 3.4 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 10.9 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 2.7 PID LKB1 PATHWAY LKB1 signaling events
0.0 2.7 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 1.6 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 0.5 PID ARF6 PATHWAY Arf6 signaling events
0.0 1.2 ST PHOSPHOINOSITIDE 3 KINASE PATHWAY PI3K Pathway
0.0 1.9 PID CERAMIDE PATHWAY Ceramide signaling pathway
0.0 0.7 PID IL3 PATHWAY IL3-mediated signaling events
0.0 0.5 PID ARF 3PATHWAY Arf1 pathway
0.0 0.5 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway
0.0 3.4 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 0.2 ST DIFFERENTIATION PATHWAY IN PC12 CELLS Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.
0.0 0.7 PID BMP PATHWAY BMP receptor signaling
0.0 0.7 PID INSULIN PATHWAY Insulin Pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 7.8 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.3 6.2 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
0.2 2.7 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.2 3.2 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.2 6.0 REACTOME COMPLEMENT CASCADE Genes involved in Complement cascade
0.2 2.4 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.1 1.7 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.1 6.4 REACTOME GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.1 1.0 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.1 2.9 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.1 0.8 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.1 1.3 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.1 2.1 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.1 5.1 REACTOME PHASE II CONJUGATION Genes involved in Phase II conjugation
0.1 0.7 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.1 6.4 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.1 1.5 REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.1 2.0 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.1 1.2 REACTOME ACYL CHAIN REMODELLING OF PG Genes involved in Acyl chain remodelling of PG
0.0 1.3 REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL Genes involved in AKT phosphorylates targets in the cytosol
0.0 1.3 REACTOME ENOS ACTIVATION AND REGULATION Genes involved in eNOS activation and regulation
0.0 1.7 REACTOME PYRUVATE METABOLISM AND CITRIC ACID TCA CYCLE Genes involved in Pyruvate metabolism and Citric Acid (TCA) cycle
0.0 0.5 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.0 2.0 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.0 1.1 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 2.7 REACTOME PPARA ACTIVATES GENE EXPRESSION Genes involved in PPARA Activates Gene Expression
0.0 0.5 REACTOME SIGNAL ATTENUATION Genes involved in Signal attenuation
0.0 0.7 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.0 0.4 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.0 1.0 REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES Genes involved in Cross-presentation of soluble exogenous antigens (endosomes)
0.0 0.4 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.0 0.5 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.0 1.2 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.0 0.3 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.0 0.5 REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0 0.4 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0 0.5 REACTOME NOD1 2 SIGNALING PATHWAY Genes involved in NOD1/2 Signaling Pathway