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GSE58827: Dynamics of the Mouse Liver

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Results for Msx2_Hoxd4

Z-value: 0.68

Motif logo

Transcription factors associated with Msx2_Hoxd4

Gene Symbol Gene ID Gene Info
ENSMUSG00000021469.10 msh homeobox 2
ENSMUSG00000101174.9 homeobox D4

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Msx2mm39_v1_chr13_-_53627110_536271100.391.7e-02Click!

Activity profile of Msx2_Hoxd4 motif

Sorted Z-values of Msx2_Hoxd4 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr2_+_4022537 3.80 ENSMUST00000177457.8
FERM domain containing 4A
chr1_-_132318039 3.75 ENSMUST00000132435.2
transmembrane and coiled-coil domains 2
chr15_+_6673167 3.32 ENSMUST00000163073.2
FYN binding protein
chr5_+_117378510 2.70 ENSMUST00000111975.3
TAO kinase 3
chrX_+_135145813 2.55 ENSMUST00000048687.11
transcription elongation factor A like 9
chr18_-_43610829 2.44 ENSMUST00000057110.11
eukaryotic translation initiation factor 3, subunit J2
chr3_-_14843512 2.26 ENSMUST00000094365.11
carbonic anhydrase 1
chr1_+_45834645 2.17 ENSMUST00000147308.2
WD repeat domain 75
chrX_+_55500170 1.89 ENSMUST00000039374.9
ENSMUST00000101553.9
ENSMUST00000186445.7
integrator complex subunit 6 like
chr6_-_136918885 1.75 ENSMUST00000111891.4
Rho, GDP dissociation inhibitor (GDI) beta
chrX_+_149330371 1.61 ENSMUST00000066337.13
ENSMUST00000112715.2
aminolevulinic acid synthase 2, erythroid
chr18_+_34973605 1.58 ENSMUST00000043484.8
receptor accessory protein 2
chr7_-_115459082 1.56 ENSMUST00000206123.2
SRY (sex determining region Y)-box 6
chr5_-_62923463 1.56 ENSMUST00000076623.8
ENSMUST00000159470.3
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
chr19_-_46033353 1.54 ENSMUST00000026252.14
ENSMUST00000156585.9
ENSMUST00000185355.7
ENSMUST00000152946.8
LIM domain binding 1
chr7_-_120673761 1.47 ENSMUST00000047194.4
immunoglobulin superfamily, member 6
chr7_+_89814713 1.39 ENSMUST00000207084.2
phosphatidylinositol binding clathrin assembly protein
chr19_+_45433899 1.35 ENSMUST00000224478.2
beta-transducin repeat containing protein
chr6_-_87510200 1.29 ENSMUST00000113637.9
ENSMUST00000071024.7
Rho GTPase activating protein 25
chr6_-_36787096 1.08 ENSMUST00000201321.2
ENSMUST00000101534.5
pleiotrophin
chr17_+_46471950 1.08 ENSMUST00000024748.14
ENSMUST00000172170.8
GTP binding protein 2
chr1_-_149836974 1.07 ENSMUST00000190507.2
ENSMUST00000070200.15
phospholipase A2, group IVA (cytosolic, calcium-dependent)
chr7_-_73191484 1.05 ENSMUST00000197642.2
ENSMUST00000026895.14
ENSMUST00000169922.9
chromodomain helicase DNA binding protein 2
chr7_-_45570828 1.00 ENSMUST00000038876.13
epithelial membrane protein 3
chr9_-_114219685 0.96 ENSMUST00000084881.5
cartilage associated protein
chr7_-_55669702 0.96 ENSMUST00000052204.6
non imprinted in Prader-Willi/Angelman syndrome 1 homolog (human)
chr11_-_79421397 0.89 ENSMUST00000103236.4
ENSMUST00000170799.8
ENSMUST00000170422.4
ecotropic viral integration site 2a
ecotropic viral integration site 2
chr1_-_165535654 0.87 ENSMUST00000097474.9
RCSD domain containing 1
chr7_-_45570254 0.85 ENSMUST00000164119.3
epithelial membrane protein 3
chr7_-_45570538 0.83 ENSMUST00000210297.2
epithelial membrane protein 3
chr18_+_4920513 0.83 ENSMUST00000126977.8
supervillin
chr11_+_67061908 0.83 ENSMUST00000018641.8
myosin, heavy polypeptide 2, skeletal muscle, adult
chr11_+_67061837 0.82 ENSMUST00000170159.8
myosin, heavy polypeptide 2, skeletal muscle, adult
chrX_+_100683662 0.82 ENSMUST00000119299.8
ENSMUST00000044475.5
O-linked N-acetylglucosamine (GlcNAc) transferase (UDP-N-acetylglucosamine:polypeptide-N-acetylglucosaminyl transferase)
chr5_-_23821523 0.81 ENSMUST00000088392.9
serine/arginine-rich protein specific kinase 2
chr6_+_68233361 0.79 ENSMUST00000103320.3
immunoglobulin kappa variable 14-111
chrX_+_158491589 0.78 ENSMUST00000080394.13
SH3-domain kinase binding protein 1
chr7_-_115423934 0.77 ENSMUST00000169129.8
SRY (sex determining region Y)-box 6
chr14_+_79753055 0.77 ENSMUST00000110835.3
ENSMUST00000227192.2
E74-like factor 1
chr2_-_84255602 0.75 ENSMUST00000074262.9
calcitonin receptor-like
chr7_-_45570674 0.75 ENSMUST00000210939.2
epithelial membrane protein 3
chr9_-_107648144 0.73 ENSMUST00000183248.3
ENSMUST00000182022.8
ENSMUST00000035199.13
ENSMUST00000182659.8
RNA binding motif protein 5
chr6_-_129449739 0.72 ENSMUST00000112076.9
ENSMUST00000184581.3
C-type lectin domain family 7, member a
chr2_-_163259012 0.71 ENSMUST00000127038.2
oxidative stress responsive serine rich 1
chrX_+_158086253 0.71 ENSMUST00000112491.2
ribosomal protein S6 kinase polypeptide 3
chr6_+_136495784 0.69 ENSMUST00000032335.13
ENSMUST00000185724.7
activating transcription factor 7 interacting protein
chr18_+_7905440 0.67 ENSMUST00000170854.2
WW domain containing adaptor with coiled-coil
chr2_-_45002902 0.66 ENSMUST00000076836.13
ENSMUST00000176732.8
ENSMUST00000200844.4
zinc finger E-box binding homeobox 2
chr6_+_83142902 0.64 ENSMUST00000077407.12
ENSMUST00000113913.8
ENSMUST00000130212.8
dynactin 1
chr1_-_80255156 0.62 ENSMUST00000168372.2
cullin 3
chr2_-_73284262 0.58 ENSMUST00000102679.8
WAS/WASL interacting protein family, member 1
chr1_+_128079543 0.58 ENSMUST00000189317.3
R3H domain containing 1
chr11_+_98689479 0.58 ENSMUST00000037930.13
male specific lethal 1
chr5_+_65505657 0.57 ENSMUST00000031096.11
klotho beta
chr13_-_100753419 0.57 ENSMUST00000168772.2
ENSMUST00000163163.9
ENSMUST00000022137.14
MARVEL (membrane-associating) domain containing 2
chr9_-_56151334 0.56 ENSMUST00000188142.7
pseudopodium-enriched atypical kinase 1
chr6_+_29361408 0.55 ENSMUST00000156163.2
calumenin
chr17_+_71923210 0.53 ENSMUST00000047086.10
WD repeat domain 43
chr4_+_3940747 0.50 ENSMUST00000119403.2
coiled-coil-helix-coiled-coil-helix domain containing 7
chr2_+_85809620 0.50 ENSMUST00000056849.3
olfactory receptor 1030
chr2_-_59955995 0.49 ENSMUST00000112550.8
bromodomain adjacent to zinc finger domain, 2B
chr3_+_40755211 0.49 ENSMUST00000204473.2
polo like kinase 4
chr10_+_5543769 0.48 ENSMUST00000051809.10
myc target 1
chr6_+_34722887 0.44 ENSMUST00000123823.8
ENSMUST00000136907.8
caldesmon 1
chr3_+_84859453 0.43 ENSMUST00000029727.8
F-box and WD-40 domain protein 7
chr9_-_106666329 0.43 ENSMUST00000046502.7
RAD54 like 2 (S. cerevisiae)
chr5_-_72325482 0.42 ENSMUST00000196241.2
ENSMUST00000013693.11
COMM domain containing 8
chr11_-_74615496 0.42 ENSMUST00000021091.15
platelet-activating factor acetylhydrolase, isoform 1b, subunit 1
chr17_-_37523969 0.39 ENSMUST00000060728.7
ENSMUST00000216318.2
olfactory receptor 95
chr6_+_136495818 0.38 ENSMUST00000186577.7
activating transcription factor 7 interacting protein
chr13_+_51562675 0.37 ENSMUST00000087978.5
sphingosine-1-phosphate receptor 3
chr6_-_69584812 0.37 ENSMUST00000103359.3
immunoglobulin kappa variable 4-55
chr10_+_128139191 0.37 ENSMUST00000005825.8
PAN2 poly(A) specific ribonuclease subunit
chr3_+_32490300 0.37 ENSMUST00000029201.14
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha
chr5_-_108022900 0.36 ENSMUST00000138111.8
ENSMUST00000112642.8
ecotropic viral integration site 5
chr7_-_84328553 0.36 ENSMUST00000069537.3
ENSMUST00000207865.2
ENSMUST00000178385.9
ENSMUST00000208782.2
zinc finger, AN1-type domain 6
chr19_-_24178000 0.34 ENSMUST00000233658.3
tight junction protein 2
chr13_-_76091931 0.34 ENSMUST00000022078.12
ENSMUST00000109606.3
Rho-related BTB domain containing 3
chr18_+_23885390 0.34 ENSMUST00000170802.8
ENSMUST00000155708.8
ENSMUST00000118826.9
microtubule-associated protein, RP/EB family, member 2
chr14_-_86986541 0.33 ENSMUST00000226254.2
diaphanous related formin 3
chr6_+_34722926 0.33 ENSMUST00000126181.8
caldesmon 1
chr15_+_41694317 0.31 ENSMUST00000166917.3
ENSMUST00000230127.2
ENSMUST00000230131.2
oxidation resistance 1
chr13_-_100753181 0.31 ENSMUST00000225754.2
MARVEL (membrane-associating) domain containing 2
chr1_+_179788675 0.30 ENSMUST00000076687.12
ENSMUST00000097450.10
ENSMUST00000212756.2
CDC42 binding protein kinase alpha
chr1_+_179936757 0.30 ENSMUST00000143176.8
ENSMUST00000135056.8
CDC42 binding protein kinase alpha
chr6_+_34723304 0.29 ENSMUST00000142716.3
caldesmon 1
chr3_-_126918491 0.28 ENSMUST00000238781.2
ankyrin 2, brain
chr18_-_33346885 0.28 ENSMUST00000025236.9
StAR-related lipid transfer (START) domain containing 4
chr13_+_49761506 0.28 ENSMUST00000021822.7
osteoglycin
chr4_+_109092610 0.27 ENSMUST00000106628.8
calreticulin 4
chr3_+_132335575 0.27 ENSMUST00000212804.2
ENSMUST00000212852.2
GIMAP family P-loop NTPase domain containing 1
chr8_+_107757847 0.27 ENSMUST00000034388.10
vacuolar protein sorting 4A
chr10_+_127257077 0.26 ENSMUST00000168780.8
R3H domain containing 2
chr5_-_123127346 0.26 ENSMUST00000118027.8
lysine (K)-specific demethylase 2B
chr2_-_45000389 0.25 ENSMUST00000201804.4
ENSMUST00000028229.13
ENSMUST00000202187.4
ENSMUST00000153561.6
ENSMUST00000201490.2
zinc finger E-box binding homeobox 2
chr2_+_87404246 0.25 ENSMUST00000213315.2
ENSMUST00000214773.2
olfactory receptor 1129
chr14_+_27598021 0.25 ENSMUST00000211684.2
ENSMUST00000210924.2
ELKS/RAB6-interacting/CAST family member 2
chr12_-_113733922 0.25 ENSMUST00000180013.3
immunoglobulin heavy variable 2-9-1
chr6_+_29853745 0.25 ENSMUST00000064872.13
ENSMUST00000152581.8
ENSMUST00000176265.8
ENSMUST00000154079.8
S-adenosylhomocysteine hydrolase-like 2
chr10_-_129107354 0.25 ENSMUST00000204573.3
olfactory receptor 777
chr10_+_127256736 0.25 ENSMUST00000064793.13
R3H domain containing 2
chr18_+_44237577 0.25 ENSMUST00000239465.2
serine peptidase inhibitor, Kazal type 12
chr13_+_19398273 0.24 ENSMUST00000103558.3
T cell receptor gamma, constant 1
chr6_+_15196950 0.24 ENSMUST00000140557.8
ENSMUST00000131414.8
ENSMUST00000115469.8
forkhead box P2
chr10_+_127256993 0.24 ENSMUST00000170336.8
R3H domain containing 2
chr3_+_7494108 0.23 ENSMUST00000193330.2
protein kinase inhibitor, alpha
chr18_-_33346819 0.23 ENSMUST00000119991.8
ENSMUST00000118990.2
StAR-related lipid transfer (START) domain containing 4
chr7_+_122723365 0.23 ENSMUST00000205514.2
ENSMUST00000094053.7
trinucleotide repeat containing 6a
chr6_+_149226891 0.22 ENSMUST00000189837.2
retroelement silencing factor 1
chr9_+_38788422 0.22 ENSMUST00000078289.3
olfactory receptor 926
chr8_-_26609153 0.22 ENSMUST00000037182.14
hook microtubule tethering protein 3
chr1_+_157353696 0.18 ENSMUST00000111700.8
SEC16 homolog B (S. cerevisiae)
chr14_-_52273600 0.18 ENSMUST00000214342.2
olfactory receptor 221
chr8_+_31601837 0.18 ENSMUST00000046941.8
ENSMUST00000217278.2
ring finger protein 122
chr4_+_101365144 0.18 ENSMUST00000149047.8
ENSMUST00000106929.10
DnaJ heat shock protein family (Hsp40) member C6
chr19_+_31846154 0.16 ENSMUST00000224564.2
ENSMUST00000224304.2
ENSMUST00000075838.8
ENSMUST00000224400.2
APOBEC1 complementation factor
chr10_-_63039709 0.16 ENSMUST00000095580.3
myopalladin
chr9_+_74959259 0.16 ENSMUST00000170310.2
ENSMUST00000166549.2
cAMP-regulated phosphoprotein 19
chr4_-_43710231 0.16 ENSMUST00000217544.2
ENSMUST00000107862.3
olfactory receptor 71
chr8_-_49296915 0.15 ENSMUST00000211812.2
teneurin transmembrane protein 3
chr18_+_44237474 0.15 ENSMUST00000081271.7
serine peptidase inhibitor, Kazal type 12
chr17_-_29226700 0.15 ENSMUST00000233441.2
serine/threonine kinase 38
chr5_-_102217770 0.15 ENSMUST00000053177.14
ENSMUST00000174698.2
WD repeat and FYVE domain containing 3
chr6_-_30936013 0.15 ENSMUST00000101589.5
Kruppel-like factor 14
chr10_-_23977810 0.15 ENSMUST00000170267.3
trace amine-associated receptor 8C
chr2_-_88519531 0.15 ENSMUST00000213545.2
olfactory receptor 1195
chr14_+_8283087 0.14 ENSMUST00000206298.3
ENSMUST00000216079.2
olfactory receptor 720
chr19_-_55229668 0.14 ENSMUST00000069183.8
guanylate cyclase 2g
chr19_-_47680528 0.13 ENSMUST00000026045.14
ENSMUST00000086923.6
collagen, type XVII, alpha 1
chr4_+_101365052 0.13 ENSMUST00000038207.12
DnaJ heat shock protein family (Hsp40) member C6
chr2_+_36342599 0.13 ENSMUST00000072854.2
olfactory receptor 340
chr6_+_83985684 0.13 ENSMUST00000203803.3
ENSMUST00000204591.3
ENSMUST00000113823.8
ENSMUST00000153860.4
dysferlin
chr1_-_156766351 0.13 ENSMUST00000189648.2
Ral GEF with PH domain and SH3 binding motif 2
chr4_+_109092459 0.13 ENSMUST00000106631.9
calreticulin 4
chr1_-_155293141 0.12 ENSMUST00000111775.8
ENSMUST00000111774.2
xenotropic and polytropic retrovirus receptor 1
chr11_+_76795346 0.12 ENSMUST00000072633.4
transmembrane and immunoglobulin domain containing 1
chr13_+_21546990 0.11 ENSMUST00000225545.2
ENSMUST00000053293.14
zinc finger and SCAN domain containing 12
chr6_+_57180275 0.11 ENSMUST00000226892.2
ENSMUST00000227421.2
vomeronasal 1 receptor 13
chr2_+_83554741 0.11 ENSMUST00000028499.11
integrin alpha V
chr18_+_37453427 0.11 ENSMUST00000078271.4
protocadherin beta 5
chr5_+_107655487 0.10 ENSMUST00000143074.2
predicted gene 42669
chr11_-_73742280 0.10 ENSMUST00000213365.2
olfactory receptor 393
chr1_+_179788037 0.10 ENSMUST00000097453.9
ENSMUST00000111117.8
CDC42 binding protein kinase alpha
chr1_-_156766381 0.10 ENSMUST00000188656.7
Ral GEF with PH domain and SH3 binding motif 2
chr6_-_129600798 0.10 ENSMUST00000095412.10
killer cell lectin-like receptor subfamily K, member 1
chr12_-_113896002 0.09 ENSMUST00000103463.3
immunoglobulin heavy variable 14-1
chr11_-_99265721 0.09 ENSMUST00000006963.3
keratin 28
chr10_+_23952398 0.09 ENSMUST00000051133.6
trace amine-associated receptor 8A
chr16_-_59092995 0.09 ENSMUST00000216834.2
olfactory receptor 201
chr3_-_144275897 0.09 ENSMUST00000043325.9
heparan sulfate 2-O-sulfotransferase 1
chr1_+_174192688 0.08 ENSMUST00000217962.2
ENSMUST00000220394.2
olfactory receptor 417
chr4_+_13784749 0.08 ENSMUST00000098256.4
RUNX1 translocation partner 1
chr8_-_3675274 0.08 ENSMUST00000004749.7
Purkinje cell protein 2 (L7)
chr9_+_77959206 0.08 ENSMUST00000024104.9
glial cells missing homolog 1
chr14_-_36641270 0.07 ENSMUST00000182797.8
coiled-coil serine rich 2
chr6_-_129600812 0.07 ENSMUST00000168919.8
killer cell lectin-like receptor subfamily K, member 1
chr7_+_107679062 0.06 ENSMUST00000213601.2
olfactory receptor 481
chr2_+_83554868 0.06 ENSMUST00000111740.9
integrin alpha V
chr4_-_3872105 0.06 ENSMUST00000105158.2
Moloney sarcoma oncogene
chr4_-_82768958 0.06 ENSMUST00000139401.2
zinc finger, DHHC domain containing 21
chr14_+_53599724 0.05 ENSMUST00000196105.2
T cell receptor alpha variable 13N-4
chr3_+_67799510 0.05 ENSMUST00000063263.5
ENSMUST00000182006.4
IQ motif containing J
Iqcj and Schip1 fusion protein
chr14_+_8282925 0.05 ENSMUST00000217642.2
olfactory receptor 720
chr15_-_101422054 0.04 ENSMUST00000230067.3
predicted gene, 49425
chr17_-_90395771 0.04 ENSMUST00000197268.5
ENSMUST00000173917.8
neurexin I
chr5_-_121641461 0.04 ENSMUST00000079368.5
a disintegrin and metallopeptidase domain 1b
chr10_+_89906956 0.04 ENSMUST00000183109.2
ankyrin repeat and sterile alpha motif domain containing 1B
chr17_-_21006419 0.04 ENSMUST00000233605.2
ENSMUST00000232812.2
ENSMUST00000233186.2
ENSMUST00000233164.2
vomeronasal 1 receptor 228
chr6_-_13871475 0.04 ENSMUST00000139231.2
RIKEN cDNA 2610001J05 gene
chr13_+_49697919 0.03 ENSMUST00000177948.2
ENSMUST00000021820.14
asporin
chr14_-_4506874 0.03 ENSMUST00000224934.2
thyroid hormone receptor beta
chr1_+_106866678 0.03 ENSMUST00000112724.3
serine (or cysteine) peptidase inhibitor, clade B (ovalbumin), member 12
chr10_+_115405891 0.02 ENSMUST00000173620.2
RIKEN cDNA A930009A15 gene
chr2_+_109522781 0.02 ENSMUST00000111050.10
brain derived neurotrophic factor
chr15_+_79999643 0.02 ENSMUST00000135727.2
synaptogyrin 1
chr1_-_54233207 0.02 ENSMUST00000120904.8
HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2
chr2_+_20742115 0.01 ENSMUST00000114606.8
ENSMUST00000114608.3
enhancer trap locus 4
chr19_+_26727111 0.01 ENSMUST00000175842.4
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr10_+_129601351 0.01 ENSMUST00000203236.3
olfactory receptor 808
chr4_+_80752535 0.01 ENSMUST00000102831.8
tyrosinase-related protein 1
chr7_-_10011933 0.01 ENSMUST00000227719.2
ENSMUST00000228622.2
ENSMUST00000228086.2
vomeronasal 1 receptor 66
chr2_+_14828903 0.00 ENSMUST00000193800.6
calcium channel, voltage-dependent, beta 2 subunit
chr14_+_50360643 0.00 ENSMUST00000215317.2
olfactory receptor 727
chr14_-_50586329 0.00 ENSMUST00000216634.2
olfactory receptor 735
chr3_+_106020545 0.00 ENSMUST00000079132.12
ENSMUST00000139086.2
chitinase, acidic 1
chr3_+_14545751 0.00 ENSMUST00000037321.8
ENSMUST00000120484.8
ENSMUST00000120801.2
solute carrier family 7 (cationic amino acid transporter, y+ system), member 12

Network of associatons between targets according to the STRING database.

First level regulatory network of Msx2_Hoxd4

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.5 GO:0043973 histone H3-K4 acetylation(GO:0043973)
0.3 1.0 GO:1901873 regulation of post-translational protein modification(GO:1901873) negative regulation of post-translational protein modification(GO:1901874)
0.3 2.7 GO:2000234 positive regulation of ribosome biogenesis(GO:0090070) positive regulation of rRNA processing(GO:2000234)
0.3 0.8 GO:0090526 regulation of gluconeogenesis involved in cellular glucose homeostasis(GO:0090526)
0.3 1.1 GO:1904395 positive regulation of skeletal muscle acetylcholine-gated channel clustering(GO:1904395)
0.3 1.6 GO:0050916 sensory perception of sweet taste(GO:0050916)
0.2 1.4 GO:1902962 regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902962) negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902963)
0.2 1.1 GO:0070966 nuclear-transcribed mRNA catabolic process, no-go decay(GO:0070966)
0.2 2.3 GO:2000741 positive regulation of mesenchymal stem cell differentiation(GO:2000741)
0.2 1.7 GO:1901164 negative regulation of trophoblast cell migration(GO:1901164)
0.2 0.7 GO:0034285 response to sucrose(GO:0009744) response to disaccharide(GO:0034285)
0.2 1.1 GO:0031394 positive regulation of prostaglandin biosynthetic process(GO:0031394) positive regulation of unsaturated fatty acid biosynthetic process(GO:2001280)
0.2 0.8 GO:0035063 nuclear speck organization(GO:0035063)
0.2 0.6 GO:0090063 positive regulation of microtubule nucleation(GO:0090063)
0.1 0.7 GO:0071894 histone H2B conserved C-terminal lysine ubiquitination(GO:0071894)
0.1 0.4 GO:0044028 DNA hypomethylation(GO:0044028) hypomethylation of CpG island(GO:0044029)
0.1 0.8 GO:1902748 positive regulation of lens fiber cell differentiation(GO:1902748)
0.1 3.4 GO:0032060 bleb assembly(GO:0032060)
0.1 1.6 GO:0042541 hemoglobin biosynthetic process(GO:0042541)
0.1 0.5 GO:0010877 lipid transport involved in lipid storage(GO:0010877) positive regulation of bile acid biosynthetic process(GO:0070859) positive regulation of bile acid metabolic process(GO:1904253)
0.1 1.8 GO:0001778 plasma membrane repair(GO:0001778)
0.1 0.9 GO:0071474 cellular hyperosmotic response(GO:0071474)
0.1 2.7 GO:0007095 mitotic G2 DNA damage checkpoint(GO:0007095)
0.1 0.6 GO:0071630 trophectodermal cellular morphogenesis(GO:0001831) nucleus-associated proteasomal ubiquitin-dependent protein catabolic process(GO:0071630)
0.1 0.3 GO:0044878 mitotic cytokinesis checkpoint(GO:0044878)
0.1 0.4 GO:1903378 positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903378)
0.1 3.8 GO:0090162 establishment of epithelial cell polarity(GO:0090162)
0.1 0.6 GO:0090080 positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway(GO:0090080)
0.1 0.4 GO:0051661 maintenance of centrosome location(GO:0051661)
0.1 0.3 GO:0021592 fourth ventricle development(GO:0021592) initiation of neural tube closure(GO:0021993)
0.1 0.5 GO:0046601 positive regulation of centriole replication(GO:0046601)
0.1 0.2 GO:0030887 positive regulation of myeloid dendritic cell activation(GO:0030887)
0.1 3.7 GO:0042982 amyloid precursor protein metabolic process(GO:0042982)
0.1 1.0 GO:0015693 magnesium ion transport(GO:0015693)
0.1 0.3 GO:0072318 clathrin coat disassembly(GO:0072318)
0.0 0.3 GO:2001205 negative regulation of osteoclast development(GO:2001205)
0.0 2.5 GO:0006730 one-carbon metabolic process(GO:0006730)
0.0 0.2 GO:0010609 mRNA localization resulting in posttranscriptional regulation of gene expression(GO:0010609)
0.0 0.1 GO:0060018 astrocyte fate commitment(GO:0060018)
0.0 0.2 GO:0035973 aggrephagy(GO:0035973)
0.0 1.1 GO:0045898 regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045898)
0.0 1.4 GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
0.0 0.3 GO:0036371 protein localization to M-band(GO:0036309) protein localization to T-tubule(GO:0036371)
0.0 3.1 GO:0045576 mast cell activation(GO:0045576)
0.0 0.2 GO:0034454 microtubule anchoring at centrosome(GO:0034454)
0.0 0.2 GO:0048207 vesicle targeting, rough ER to cis-Golgi(GO:0048207) COPII vesicle coating(GO:0048208)
0.0 0.4 GO:0045602 negative regulation of endothelial cell differentiation(GO:0045602)
0.0 0.7 GO:0040023 nuclear migration(GO:0007097) establishment of nucleus localization(GO:0040023)
0.0 0.6 GO:0060218 hematopoietic stem cell differentiation(GO:0060218)
0.0 0.8 GO:0050860 negative regulation of T cell receptor signaling pathway(GO:0050860)
0.0 0.2 GO:0032485 regulation of Ral protein signal transduction(GO:0032485)
0.0 0.4 GO:0000291 nuclear-transcribed mRNA catabolic process, exonucleolytic(GO:0000291)
0.0 0.1 GO:1901994 negative regulation of meiotic cell cycle phase transition(GO:1901994)
0.0 0.2 GO:0090520 sphingolipid mediated signaling pathway(GO:0090520)
0.0 0.6 GO:0043984 histone H4-K16 acetylation(GO:0043984)
0.0 0.1 GO:0030202 heparin metabolic process(GO:0030202)
0.0 0.3 GO:1902083 negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.0 0.6 GO:0046827 positive regulation of protein export from nucleus(GO:0046827)
0.0 0.2 GO:0060501 positive regulation of epithelial cell proliferation involved in lung morphogenesis(GO:0060501)
0.0 0.9 GO:0061028 establishment of endothelial barrier(GO:0061028)
0.0 0.2 GO:0045974 miRNA mediated inhibition of translation(GO:0035278) negative regulation of translation, ncRNA-mediated(GO:0040033) regulation of translation, ncRNA-mediated(GO:0045974)
0.0 0.4 GO:0006625 protein targeting to peroxisome(GO:0006625) peroxisomal transport(GO:0043574) protein localization to peroxisome(GO:0072662) establishment of protein localization to peroxisome(GO:0072663)
0.0 0.2 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.0 1.1 GO:0006940 regulation of smooth muscle contraction(GO:0006940)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.6 GO:0005826 actomyosin contractile ring(GO:0005826)
0.2 1.4 GO:0070381 endosome to plasma membrane transport vesicle(GO:0070381)
0.1 2.4 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
0.1 0.4 GO:0005943 phosphatidylinositol 3-kinase complex, class IA(GO:0005943)
0.1 0.4 GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
0.1 1.1 GO:0030478 actin cap(GO:0030478)
0.1 0.9 GO:0033010 paranodal junction(GO:0033010) tricellular tight junction(GO:0061689)
0.1 0.6 GO:0072487 MSL complex(GO:0072487)
0.1 0.6 GO:0005827 polar microtubule(GO:0005827)
0.1 0.4 GO:0031251 PAN complex(GO:0031251)
0.1 0.5 GO:0098536 deuterosome(GO:0098536)
0.1 0.2 GO:0034274 Atg12-Atg5-Atg16 complex(GO:0034274) extrinsic component of autophagosome membrane(GO:0097635)
0.0 1.9 GO:0042588 zymogen granule(GO:0042588)
0.0 0.6 GO:0005869 dynactin complex(GO:0005869)
0.0 0.4 GO:0000235 astral microtubule(GO:0000235)
0.0 0.2 GO:0070695 FHF complex(GO:0070695)
0.0 1.1 GO:0043034 costamere(GO:0043034)
0.0 0.3 GO:0000815 ESCRT III complex(GO:0000815)
0.0 0.2 GO:0035068 micro-ribonucleoprotein complex(GO:0035068)
0.0 0.2 GO:0045293 mRNA editing complex(GO:0045293)
0.0 1.6 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.0 4.1 GO:0005923 bicellular tight junction(GO:0005923) occluding junction(GO:0070160)
0.0 1.4 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 0.3 GO:0035371 microtubule plus-end(GO:0035371)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.6 GO:0003870 5-aminolevulinate synthase activity(GO:0003870) N-succinyltransferase activity(GO:0016749)
0.3 0.8 GO:0016262 protein N-acetylglucosaminyltransferase activity(GO:0016262)
0.3 1.1 GO:0035373 chondroitin sulfate proteoglycan binding(GO:0035373)
0.2 0.7 GO:0004948 calcitonin receptor activity(GO:0004948)
0.2 2.3 GO:0004064 arylesterase activity(GO:0004064)
0.2 1.7 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.2 0.6 GO:0031208 POZ domain binding(GO:0031208)
0.1 1.1 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.1 1.5 GO:0030274 LIM domain binding(GO:0030274)
0.1 1.4 GO:0032050 clathrin heavy chain binding(GO:0032050)
0.1 2.7 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.1 0.4 GO:0050816 phosphothreonine binding(GO:0050816)
0.1 0.2 GO:0032394 MHC class Ib receptor activity(GO:0032394)
0.0 1.0 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.0 2.5 GO:0050699 WW domain binding(GO:0050699)
0.0 0.2 GO:0004013 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.0 2.4 GO:0003743 translation initiation factor activity(GO:0003743)
0.0 0.1 GO:0000822 inositol hexakisphosphate binding(GO:0000822)
0.0 0.4 GO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol bisphosphate kinase activity(GO:0052813)
0.0 1.1 GO:0070840 dynein complex binding(GO:0070840)
0.0 0.2 GO:0003831 beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity(GO:0003831)
0.0 0.4 GO:0038036 sphingosine-1-phosphate receptor activity(GO:0038036)
0.0 1.6 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.0 0.8 GO:0070412 R-SMAD binding(GO:0070412)
0.0 4.4 GO:0030674 protein binding, bridging(GO:0030674)
0.0 0.7 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.0 0.8 GO:0071889 14-3-3 protein binding(GO:0071889)
0.0 1.4 GO:0045309 protein phosphorylated amino acid binding(GO:0045309)
0.0 0.5 GO:0017127 cholesterol transporter activity(GO:0017127)
0.0 0.4 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.0 0.3 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0 0.7 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0 0.5 GO:0017134 fibroblast growth factor binding(GO:0017134)
0.0 0.1 GO:0001594 trace-amine receptor activity(GO:0001594)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.7 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.0 1.1 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.0 0.7 SA B CELL RECEPTOR COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.0 1.6 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.0 1.6 PID ARF6 PATHWAY Arf6 signaling events
0.0 2.0 PID FCER1 PATHWAY Fc-epsilon receptor I signaling in mast cells
0.0 2.5 PID TCR PATHWAY TCR signaling in naïve CD4+ T cells
0.0 0.6 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway
0.0 1.6 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.0 0.6 PID NCADHERIN PATHWAY N-cadherin signaling events
0.0 0.8 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.0 0.8 PID ERBB1 INTERNALIZATION PATHWAY Internalization of ErbB1
0.0 0.3 PID S1P META PATHWAY Sphingosine 1-phosphate (S1P) pathway
0.0 0.4 PID MYC PATHWAY C-MYC pathway
0.0 1.0 PID CDC42 PATHWAY CDC42 signaling events
0.0 0.6 PID FGF PATHWAY FGF signaling pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.3 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.1 1.6 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.1 1.1 REACTOME ACYL CHAIN REMODELLING OF PS Genes involved in Acyl chain remodelling of PS
0.0 1.4 REACTOME PROLACTIN RECEPTOR SIGNALING Genes involved in Prolactin receptor signaling
0.0 0.8 REACTOME EGFR DOWNREGULATION Genes involved in EGFR downregulation
0.0 0.7 REACTOME RECYCLING PATHWAY OF L1 Genes involved in Recycling pathway of L1
0.0 1.1 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 1.7 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.0 4.6 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.0 0.4 REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR Genes involved in Signaling by constitutively active EGFR
0.0 1.5 REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.0 0.3 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0 1.1 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 0.5 REACTOME STEROID HORMONES Genes involved in Steroid hormones