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GSE58827: Dynamics of the Mouse Liver

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Results for Nkx2-9

Z-value: 1.43

Motif logo

Transcription factors associated with Nkx2-9

Gene Symbol Gene ID Gene Info
ENSMUSG00000058669.8 NK2 homeobox 9

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Nkx2-9mm39_v1_chr12_-_56660054_56660113-0.573.2e-04Click!

Activity profile of Nkx2-9 motif

Sorted Z-values of Nkx2-9 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr2_+_172864153 13.33 ENSMUST00000173997.2
RNA binding motif protein 38
chr4_-_119047202 12.28 ENSMUST00000239029.2
ENSMUST00000138395.9
ENSMUST00000156746.3
erythroblast membrane-associated protein
chr4_-_119047167 10.55 ENSMUST00000030396.15
erythroblast membrane-associated protein
chr9_+_98372575 10.06 ENSMUST00000035029.3
retinol binding protein 2, cellular
chr4_-_119047180 8.61 ENSMUST00000150864.3
ENSMUST00000141227.9
erythroblast membrane-associated protein
chr2_+_103799873 8.56 ENSMUST00000123437.8
LIM domain only 2
chr4_-_119047146 8.51 ENSMUST00000124626.9
erythroblast membrane-associated protein
chr11_+_117740111 7.56 ENSMUST00000093906.5
baculoviral IAP repeat-containing 5
chr9_+_54606832 4.57 ENSMUST00000070070.8
DnaJ heat shock protein family (Hsp40) member A4
chr10_-_62258195 4.19 ENSMUST00000020277.9
hexokinase domain containing 1
chr9_+_72345801 4.13 ENSMUST00000184604.8
ENSMUST00000034746.10
meiosis-specific nuclear structural protein 1
chr12_+_24758724 4.03 ENSMUST00000153058.8
ribonucleotide reductase M2
chr11_+_117740077 3.95 ENSMUST00000081387.11
baculoviral IAP repeat-containing 5
chr12_+_24758968 3.67 ENSMUST00000154588.2
ribonucleotide reductase M2
chr1_-_181669891 3.58 ENSMUST00000193028.2
ENSMUST00000191878.6
ENSMUST00000005003.12
lamin B receptor
chrX_-_101232978 3.32 ENSMUST00000033683.8
ribosomal protein S4, X-linked
chr16_-_58344548 3.16 ENSMUST00000114357.10
ST3 beta-galactoside alpha-2,3-sialyltransferase 6
chr19_-_40576782 3.08 ENSMUST00000176939.8
aldehyde dehydrogenase 18 family, member A1
chr11_-_68864666 3.01 ENSMUST00000038644.5
RAN guanine nucleotide release factor
chr16_-_58344602 2.90 ENSMUST00000114358.9
ST3 beta-galactoside alpha-2,3-sialyltransferase 6
chr4_-_61259997 2.83 ENSMUST00000071005.9
ENSMUST00000075206.12
major urinary protein 14
chrX_+_134894573 2.74 ENSMUST00000058119.9
adipocyte-related X-chromosome expressed sequence 2
chr4_-_60777462 2.65 ENSMUST00000211875.2
major urinary protein 22
chr4_-_60222580 2.63 ENSMUST00000095058.5
ENSMUST00000163931.8
major urinary protein 8
chr15_+_79575046 2.61 ENSMUST00000046463.10
GTP binding protein 1
chr4_-_61259801 2.56 ENSMUST00000125461.8
major urinary protein 14
chr4_-_61700450 2.50 ENSMUST00000107477.2
ENSMUST00000080606.9
major urinary protein 19
chr7_-_19411866 2.41 ENSMUST00000142352.9
apolipoprotein C-II
chr11_+_114559350 2.39 ENSMUST00000106602.10
ENSMUST00000077915.10
ENSMUST00000106599.8
ENSMUST00000082092.5
ribosomal protein L38
chr1_+_63215976 2.23 ENSMUST00000129339.8
eukaryotic translation elongation factor 1 beta 2
chr7_+_45084257 2.23 ENSMUST00000003964.17
glycogen synthase 1, muscle
chr6_-_40976413 2.19 ENSMUST00000166306.3
predicted gene 2663
chr9_-_45923908 2.15 ENSMUST00000217514.2
platelet-activating factor acetylhydrolase, isoform 1b, subunit 2
chr13_+_93441447 2.10 ENSMUST00000109497.8
ENSMUST00000109498.8
ENSMUST00000060490.11
ENSMUST00000109492.9
ENSMUST00000109496.8
ENSMUST00000109495.8
homer scaffolding protein 1
chr6_-_142453531 2.09 ENSMUST00000134191.3
ENSMUST00000239397.2
ENSMUST00000239395.2
ENSMUST00000032373.12
lactate dehydrogenase B
chr1_+_74193138 2.05 ENSMUST00000027372.8
ENSMUST00000106899.4
chemokine (C-X-C motif) receptor 2
chr1_+_128031055 1.92 ENSMUST00000188381.7
ENSMUST00000187900.7
ENSMUST00000036288.11
R3H domain containing 1
chr1_-_156301821 1.91 ENSMUST00000188027.2
ENSMUST00000187507.7
ENSMUST00000189661.7
sterol O-acyltransferase 1
chr7_+_45084300 1.90 ENSMUST00000211150.2
glycogen synthase 1, muscle
chr9_-_99592116 1.84 ENSMUST00000035048.12
claudin 18
chr16_-_58344497 1.82 ENSMUST00000151510.2
ENSMUST00000126978.8
ENSMUST00000123918.8
ST3 beta-galactoside alpha-2,3-sialyltransferase 6
chr2_+_121337226 1.75 ENSMUST00000099473.10
ENSMUST00000110602.9
WD repeat domain 76
chr17_+_24939225 1.72 ENSMUST00000146867.2
ribosomal protein S2
chr7_-_110462446 1.67 ENSMUST00000033050.5
lymphatic vessel endothelial hyaluronan receptor 1
chr19_-_5779648 1.61 ENSMUST00000116558.3
ENSMUST00000099955.4
ENSMUST00000161368.2
family with sequence similarity 89, member B
chr4_-_43010225 1.57 ENSMUST00000030165.5
Fanconi anemia, complementation group G
chr3_+_113824181 1.51 ENSMUST00000123619.8
ENSMUST00000092155.12
collagen, type XI, alpha 1
chr7_-_33929667 1.51 ENSMUST00000206415.2
glucose-6-phosphate isomerase 1
chr11_-_80670815 1.46 ENSMUST00000041065.14
ENSMUST00000070997.6
myosin ID
chr7_-_33929708 1.40 ENSMUST00000038027.6
glucose-6-phosphate isomerase 1
chr9_-_99592058 1.32 ENSMUST00000136429.8
claudin 18
chr1_-_136273811 1.20 ENSMUST00000048309.12
calmodulin regulated spectrin-associated protein family, member 2
chr6_-_113411489 1.18 ENSMUST00000133348.2
cell death-inducing DFFA-like effector c
chr11_+_30904390 1.18 ENSMUST00000020551.13
ENSMUST00000117883.2
ankyrin repeat and SOCS box-containing 3
chr3_+_37474422 1.16 ENSMUST00000029277.13
ENSMUST00000198968.2
spermatogenesis associated 5
chr2_+_121337195 1.15 ENSMUST00000028676.12
WD repeat domain 76
chr10_+_79518138 1.14 ENSMUST00000166603.2
ENSMUST00000219791.2
ENSMUST00000219930.2
ENSMUST00000218964.2
cell division cycle 34
chr10_+_87926932 1.11 ENSMUST00000048621.8
pro-melanin-concentrating hormone
chr12_-_113561594 1.06 ENSMUST00000103444.3
immunoglobulin heavy variable 5-4
chr7_+_88079465 1.06 ENSMUST00000107256.4
RAB38, member RAS oncogene family
chr12_-_113666198 1.01 ENSMUST00000103450.4
immunoglobulin heavy variable 5-12
chr10_+_68559553 1.01 ENSMUST00000080995.8
transmembrane protein 26
chr8_+_96360081 1.00 ENSMUST00000034094.11
ENSMUST00000212434.2
GINS complex subunit 3 (Psf3 homolog)
chr18_-_43610829 0.96 ENSMUST00000057110.11
eukaryotic translation initiation factor 3, subunit J2
chr6_-_38331482 0.93 ENSMUST00000031850.10
ENSMUST00000114898.3
zinc finger CCCH type, antiviral 1
chr13_-_59890564 0.90 ENSMUST00000055343.3
RIKEN cDNA 1700014D04 gene
chr6_+_135339929 0.89 ENSMUST00000032330.16
epithelial membrane protein 1
chrX_+_41238193 0.89 ENSMUST00000115073.9
ENSMUST00000115072.8
stromal antigen 2
chr6_-_78445846 0.89 ENSMUST00000032089.3
regenerating islet-derived 3 gamma
chr5_-_138185438 0.88 ENSMUST00000110937.8
ENSMUST00000139276.2
ENSMUST00000048698.14
ENSMUST00000123415.8
TATA-box binding protein associated factor 6
chr9_-_56068282 0.88 ENSMUST00000034876.10
tetraspanin 3
chr6_+_33226020 0.86 ENSMUST00000052266.15
ENSMUST00000090381.11
ENSMUST00000115080.2
exocyst complex component 4
chr12_-_113589576 0.84 ENSMUST00000103446.2
immunoglobulin heavy variable 5-6
chr9_+_57411279 0.81 ENSMUST00000080514.9
ribonuclease P/MRP 25 subunit
chr12_-_114443071 0.79 ENSMUST00000103492.2
immunoglobulin heavy variable 10-1
chr12_-_113802603 0.78 ENSMUST00000103458.3
ENSMUST00000193652.2
immunoglobulin heavy variable 5-16
chr8_-_81607140 0.76 ENSMUST00000210676.2
growth factor receptor bound protein 2-associated protein 1
chr11_-_103844870 0.75 ENSMUST00000103075.11
N-ethylmaleimide sensitive fusion protein
chr18_-_60981981 0.75 ENSMUST00000177172.8
ENSMUST00000175934.8
ENSMUST00000176630.8
treacle ribosome biogenesis factor 1
chr2_-_121337120 0.74 ENSMUST00000089926.6
microfibrillar-associated protein 1A
chr8_-_81607109 0.71 ENSMUST00000034150.10
growth factor receptor bound protein 2-associated protein 1
chr11_-_32217547 0.68 ENSMUST00000109389.9
ENSMUST00000129010.2
ENSMUST00000020530.12
nitrogen permease regulator-like 3
chr12_-_113700190 0.67 ENSMUST00000103452.3
ENSMUST00000192264.2
immunoglobulin heavy variable 5-9-1
chr12_-_115825934 0.66 ENSMUST00000198777.2
immunoglobulin heavy variable 1-77
chr8_+_70945806 0.63 ENSMUST00000008032.14
cytokine receptor-like factor 1
chr10_+_94034817 0.59 ENSMUST00000020209.16
ENSMUST00000179990.8
NADH:ubiquinone oxidoreductase subunit A12
chr12_-_113823290 0.59 ENSMUST00000103459.5
immunoglobulin heavy variable 5-17
chr19_+_12257218 0.55 ENSMUST00000207186.4
ENSMUST00000207915.2
olfactory receptor 1434
chr11_+_106680062 0.55 ENSMUST00000103068.10
ENSMUST00000018516.11
centrosomal protein 95
chr18_+_37102969 0.54 ENSMUST00000194544.2
predicted gene, 37013
chr3_-_154760978 0.54 ENSMUST00000064076.6
TNNI3 interacting kinase
chr2_-_105832353 0.52 ENSMUST00000155811.2
DnaJ heat shock protein family (Hsp40) member C24
chr5_-_138185686 0.52 ENSMUST00000110936.8
TATA-box binding protein associated factor 6
chr6_+_136530970 0.50 ENSMUST00000189535.2
activating transcription factor 7 interacting protein
chr7_+_75259778 0.50 ENSMUST00000207923.2
A kinase (PRKA) anchor protein 13
chrX_-_94701983 0.49 ENSMUST00000119640.8
ENSMUST00000120620.8
ENSMUST00000044382.7
zinc finger, C4H2 domain containing
chr4_-_61753422 0.49 ENSMUST00000082287.3
major urinary protein 5
chr11_-_106679983 0.49 ENSMUST00000129585.8
DEAD box helicase 5
chr14_+_53007210 0.49 ENSMUST00000178768.4
T cell receptor alpha variable 7D-4
chr16_+_17716480 0.48 ENSMUST00000055374.8
testis-specific serine kinase 2
chrX_+_7744535 0.47 ENSMUST00000033495.15
proviral integration site 2
chr12_-_113860566 0.44 ENSMUST00000103474.5
immunoglobulin heavy variable 7-1
chr11_+_69920849 0.43 ENSMUST00000143920.4
discs large MAGUK scaffold protein 4
chr13_+_109397184 0.42 ENSMUST00000153234.8
phosphodiesterase 4D, cAMP specific
chr4_+_88760098 0.42 ENSMUST00000094973.5
interferon alpha 4
chr4_+_129714494 0.41 ENSMUST00000165853.2
protein tyrosine phosphatase 4a2
chr3_+_159545309 0.39 ENSMUST00000068952.10
ENSMUST00000198878.2
wntless WNT ligand secretion mediator
chrX_-_101950075 0.39 ENSMUST00000120808.8
ENSMUST00000121197.8
DMRT-like family C1a
chr17_-_26080429 0.38 ENSMUST00000079461.15
ENSMUST00000176923.9
WD repeat domain 90
chr19_-_12147438 0.37 ENSMUST00000207679.3
ENSMUST00000219261.2
olfactory receptor 1555, pseudogene 1
chr11_+_69920956 0.37 ENSMUST00000232115.2
discs large MAGUK scaffold protein 4
chr12_-_114502585 0.37 ENSMUST00000103496.4
immunoglobulin heavy variable V1-7
chr11_+_69920542 0.37 ENSMUST00000232266.2
ENSMUST00000132597.5
discs large MAGUK scaffold protein 4
chr7_+_30121147 0.37 ENSMUST00000108176.9
nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, delta
chr14_+_54440591 0.35 ENSMUST00000103725.2
T cell receptor alpha joining 16
chr3_-_75389047 0.34 ENSMUST00000193989.4
ENSMUST00000203169.3
WD repeat domain 49
chr9_+_44238089 0.33 ENSMUST00000054708.5
dolichyl-phosphate (UDP-N-acetylglucosamine) acetylglucosaminephosphotransferase 1 (GlcNAc-1-P transferase)
chr1_-_74639723 0.33 ENSMUST00000127938.8
ENSMUST00000154874.8
ring finger protein 25
chr18_-_65527078 0.32 ENSMUST00000035548.16
alpha-kinase 2
chr5_-_24650164 0.31 ENSMUST00000115043.8
ENSMUST00000115041.2
ENSMUST00000030800.13
Fas-activated serine/threonine kinase
chr12_-_115410489 0.30 ENSMUST00000194581.2
immunoglobulin heavy variable 1-62-2
chr1_+_59296065 0.30 ENSMUST00000160662.8
ENSMUST00000114248.3
cyclin-dependent kinase 15
chr9_-_48822399 0.29 ENSMUST00000003826.8
5-hydroxytryptamine (serotonin) receptor 3A
chr12_-_114487525 0.29 ENSMUST00000103495.3
immunoglobulin heavy variable V10-3
chr13_-_64645606 0.28 ENSMUST00000180282.2
family with sequence similarity 240 member B
chr10_-_129951252 0.26 ENSMUST00000213145.2
olfactory receptor 823
chr11_+_69917640 0.25 ENSMUST00000135916.9
ENSMUST00000232659.2
discs large MAGUK scaffold protein 4
chr5_+_91222470 0.25 ENSMUST00000031324.6
epiregulin
chr7_-_101667346 0.25 ENSMUST00000209844.2
ENSMUST00000211502.2
ENSMUST00000094134.5
interleukin 18 binding protein
chr9_+_108368032 0.25 ENSMUST00000166103.9
ENSMUST00000085044.14
ENSMUST00000193678.6
ENSMUST00000178075.8
ubiquitin specific peptidase 19
chr12_-_75463555 0.24 ENSMUST00000051079.4
glycoprotein hormone beta 5
chr3_-_59009231 0.23 ENSMUST00000085040.5
G protein-coupled receptor 171
chr11_+_76792977 0.22 ENSMUST00000102495.8
transmembrane and immunoglobulin domain containing 1
chrX_+_13499008 0.21 ENSMUST00000096492.4
G protein-coupled receptor 34
chr1_+_61017057 0.20 ENSMUST00000027162.12
ENSMUST00000102827.4
inducible T cell co-stimulator
chr2_+_67004178 0.20 ENSMUST00000239009.2
ENSMUST00000238912.2
xin actin-binding repeat containing 2
chr17_+_35878332 0.20 ENSMUST00000044326.5
RIKEN cDNA 2300002M23 gene
chr17_-_26204621 0.20 ENSMUST00000041641.9
ENSMUST00000212520.2
calpain 15
chr11_-_22932090 0.19 ENSMUST00000160826.2
ENSMUST00000093270.6
ENSMUST00000071068.9
ENSMUST00000159081.8
COMM domain containing 1B
COMM domain containing 1
chr13_-_32960379 0.19 ENSMUST00000230119.2
myosin light chain kinase family, member 4
chr15_-_98816012 0.18 ENSMUST00000023736.10
limb region 1 like
chr11_-_106679312 0.18 ENSMUST00000021062.12
DEAD box helicase 5
chr3_-_37180093 0.17 ENSMUST00000029275.6
interleukin 2
chr6_-_141954471 0.17 ENSMUST00000111832.3
predicted gene 6614
chr5_-_35259847 0.16 ENSMUST00000153664.2
low density lipoprotein receptor-related protein associated protein 1
chr16_-_48232770 0.16 ENSMUST00000212197.2
predicted gene 5485
chr12_-_114793177 0.15 ENSMUST00000103511.2
ENSMUST00000195735.2
immunoglobulin heavy variable 1-31
chr7_-_133966588 0.10 ENSMUST00000172947.8
DNA segment, Chr 7, ERATO Doi 443, expressed
chr17_-_37548054 0.07 ENSMUST00000213328.2
ENSMUST00000214848.2
ENSMUST00000214622.2
ENSMUST00000073667.6
ENSMUST00000216225.2
olfactory receptor 97
chr6_-_42453259 0.07 ENSMUST00000204324.3
ENSMUST00000203396.3
olfactory receptor 457
chr7_+_34885782 0.07 ENSMUST00000135452.8
ENSMUST00000001854.12
solute carrier family 7 (cationic amino acid transporter, y+ system), member 10
chr16_+_24266829 0.06 ENSMUST00000078988.10
LIM domain containing preferred translocation partner in lipoma
chr12_-_114579763 0.06 ENSMUST00000103500.2
immunoglobulin heavy variable V1-12
chr4_-_88602149 0.05 ENSMUST00000105147.2
interferon alpha 2
chr12_+_103281188 0.05 ENSMUST00000189885.2
ENSMUST00000179363.2
family with sequence similarity 181, member A
chr17_+_34062059 0.05 ENSMUST00000002379.15
CD320 antigen
chr11_-_102837514 0.05 ENSMUST00000057849.6
complement component 1, q subcomponent-like 1
chr17_-_32491339 0.04 ENSMUST00000237008.2
bromodomain containing 4
chr1_+_24216691 0.03 ENSMUST00000054588.15
collagen, type IX, alpha 1
chr12_-_115567853 0.03 ENSMUST00000103538.3
ENSMUST00000198646.2
immunoglobulin heavy variable V1-67
chr6_+_42263644 0.02 ENSMUST00000163936.8
chloride channel, voltage-sensitive 1
chr7_-_103814019 0.02 ENSMUST00000154555.2
ENSMUST00000051137.15
olfactomedin 5
chr6_+_42263609 0.02 ENSMUST00000238845.2
ENSMUST00000031894.13
chloride channel, voltage-sensitive 1
chr5_+_117552042 0.01 ENSMUST00000180430.2
kinase suppressor of ras 2
chr8_+_67150055 0.01 ENSMUST00000039303.7
neuropeptide Y receptor Y1
chr14_+_53210216 0.01 ENSMUST00000103599.3
T cell receptor alpha variable 3D-3
chr6_-_71609881 0.00 ENSMUST00000065509.11
ENSMUST00000207023.2
lysine (K)-specific demethylase 3A

Network of associatons between targets according to the STRING database.

First level regulatory network of Nkx2-9

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.6 11.5 GO:0031536 positive regulation of exit from mitosis(GO:0031536)
1.1 10.1 GO:0006776 vitamin A metabolic process(GO:0006776)
1.0 3.1 GO:0006592 ornithine biosynthetic process(GO:0006592)
0.7 13.3 GO:0006977 DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest(GO:0006977)
0.6 1.9 GO:0042986 positive regulation of amyloid precursor protein biosynthetic process(GO:0042986)
0.6 2.4 GO:0060697 positive regulation of phospholipid catabolic process(GO:0060697)
0.5 8.6 GO:0097067 cellular response to thyroid hormone stimulus(GO:0097067)
0.5 3.2 GO:2001205 negative regulation of osteoclast development(GO:2001205)
0.4 1.1 GO:0046005 positive regulation of circadian sleep/wake cycle, REM sleep(GO:0046005)
0.4 2.9 GO:0061718 NADH regeneration(GO:0006735) canonical glycolysis(GO:0061621) glucose catabolic process to pyruvate(GO:0061718)
0.3 2.1 GO:0033030 negative regulation of neutrophil apoptotic process(GO:0033030)
0.3 7.7 GO:0009263 deoxyribonucleotide biosynthetic process(GO:0009263)
0.3 3.0 GO:0098909 regulation of cardiac muscle cell action potential involved in regulation of contraction(GO:0098909)
0.3 4.6 GO:0090084 negative regulation of inclusion body assembly(GO:0090084)
0.2 2.4 GO:0048318 axial mesoderm development(GO:0048318)
0.2 4.1 GO:0070986 left/right axis specification(GO:0070986)
0.2 1.5 GO:0035989 tendon development(GO:0035989)
0.2 4.2 GO:0046835 carbohydrate phosphorylation(GO:0046835)
0.2 2.1 GO:0019244 lactate biosynthetic process from pyruvate(GO:0019244)
0.2 1.1 GO:0090383 platelet dense granule organization(GO:0060155) phagosome acidification(GO:0090383) melanosome assembly(GO:1903232)
0.1 2.9 GO:2000001 regulation of DNA damage checkpoint(GO:2000001)
0.1 0.4 GO:0061357 positive regulation of Wnt protein secretion(GO:0061357)
0.1 7.9 GO:0018279 protein N-linked glycosylation via asparagine(GO:0018279)
0.1 0.9 GO:0051715 cytolysis in other organism(GO:0051715)
0.1 1.4 GO:0099628 receptor diffusion trapping(GO:0098953) postsynaptic neurotransmitter receptor diffusion trapping(GO:0098970) neurotransmitter receptor diffusion trapping(GO:0099628)
0.1 2.1 GO:2001256 regulation of store-operated calcium entry(GO:2001256)
0.1 1.7 GO:0001731 formation of translation preinitiation complex(GO:0001731)
0.1 1.1 GO:0043951 negative regulation of cAMP-mediated signaling(GO:0043951)
0.1 1.4 GO:0006027 glycosaminoglycan catabolic process(GO:0006027)
0.1 3.5 GO:0061014 positive regulation of mRNA catabolic process(GO:0061014)
0.1 0.9 GO:0048341 paraxial mesoderm formation(GO:0048341)
0.1 0.7 GO:1903800 positive regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903800)
0.1 0.8 GO:0001682 tRNA 5'-leader removal(GO:0001682)
0.1 0.7 GO:0014029 neural crest formation(GO:0014029)
0.1 1.5 GO:0035728 response to hepatocyte growth factor(GO:0035728)
0.1 0.2 GO:1902071 regulation of hypoxia-inducible factor-1alpha signaling pathway(GO:1902071)
0.1 0.6 GO:2000672 negative regulation of motor neuron apoptotic process(GO:2000672)
0.1 0.5 GO:0071883 activation of MAPK activity by adrenergic receptor signaling pathway(GO:0071883)
0.1 4.1 GO:0005978 glycogen biosynthetic process(GO:0005978) glucan biosynthetic process(GO:0009250)
0.1 0.3 GO:0001550 ovarian cumulus expansion(GO:0001550) fused antrum stage(GO:0048165)
0.0 7.4 GO:0006910 phagocytosis, recognition(GO:0006910)
0.0 0.3 GO:0019348 dolichol metabolic process(GO:0019348)
0.0 1.2 GO:0034389 lipid particle organization(GO:0034389)
0.0 0.4 GO:0070245 positive regulation of thymocyte apoptotic process(GO:0070245)
0.0 0.4 GO:0032876 negative regulation of DNA endoreduplication(GO:0032876)
0.0 0.2 GO:0010916 regulation of very-low-density lipoprotein particle clearance(GO:0010915) negative regulation of very-low-density lipoprotein particle clearance(GO:0010916)
0.0 3.6 GO:0016126 sterol biosynthetic process(GO:0016126)
0.0 2.2 GO:0006414 translational elongation(GO:0006414)
0.0 2.6 GO:0016239 positive regulation of macroautophagy(GO:0016239)
0.0 0.4 GO:1901898 negative regulation of relaxation of cardiac muscle(GO:1901898)
0.0 0.9 GO:0032060 bleb assembly(GO:0032060)
0.0 0.5 GO:0086069 bundle of His cell to Purkinje myocyte communication(GO:0086069)
0.0 0.2 GO:0046013 regulation of T cell homeostatic proliferation(GO:0046013)
0.0 0.2 GO:0035589 G-protein coupled purinergic nucleotide receptor signaling pathway(GO:0035589)
0.0 0.1 GO:0015825 L-serine transport(GO:0015825)
0.0 0.7 GO:2000785 regulation of autophagosome assembly(GO:2000785)
0.0 0.2 GO:0002155 thyroid hormone mediated signaling pathway(GO:0002154) regulation of thyroid hormone mediated signaling pathway(GO:0002155)
0.0 1.6 GO:0001541 ovarian follicle development(GO:0001541)
0.0 0.5 GO:0033141 positive regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033141)
0.0 0.7 GO:0001921 positive regulation of receptor recycling(GO:0001921)
0.0 1.5 GO:0006367 transcription initiation from RNA polymerase II promoter(GO:0006367)
0.0 0.2 GO:1900037 regulation of cellular response to hypoxia(GO:1900037)
0.0 1.5 GO:0010923 negative regulation of phosphatase activity(GO:0010923)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
2.9 11.5 GO:0031021 interphase microtubule organizing center(GO:0031021)
1.3 7.7 GO:0005971 ribonucleoside-diphosphate reductase complex(GO:0005971)
0.8 2.4 GO:0070992 translation initiation complex(GO:0070992)
0.3 2.2 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.2 2.4 GO:0034363 intermediate-density lipoprotein particle(GO:0034363)
0.2 2.1 GO:0042629 mast cell granule(GO:0042629)
0.2 2.6 GO:0000177 cytoplasmic exosome (RNase complex)(GO:0000177)
0.2 3.6 GO:0005639 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229)
0.1 0.7 GO:1990130 Iml1 complex(GO:1990130)
0.1 0.8 GO:0000172 ribonuclease MRP complex(GO:0000172)
0.1 1.1 GO:0033162 melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.1 0.6 GO:0097058 CRLF-CLCF1 complex(GO:0097058)
0.1 1.5 GO:0098643 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.1 0.3 GO:1904602 serotonin-activated cation-selective channel complex(GO:1904602)
0.1 1.2 GO:0036449 microtubule minus-end(GO:0036449)
0.1 1.6 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.1 5.0 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.1 1.4 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.1 0.7 GO:0071141 SMAD protein complex(GO:0071141)
0.1 0.9 GO:0032584 growth cone membrane(GO:0032584)
0.1 1.4 GO:0033276 transcription factor TFTC complex(GO:0033276)
0.1 7.4 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.1 1.0 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
0.0 0.0 GO:0044301 climbing fiber(GO:0044301)
0.0 2.9 GO:0060170 ciliary membrane(GO:0060170)
0.0 1.5 GO:0097440 apical dendrite(GO:0097440)
0.0 4.1 GO:0016234 inclusion body(GO:0016234)
0.0 0.5 GO:0001527 microfibril(GO:0001527) fibril(GO:0043205)
0.0 0.9 GO:0044216 other organism(GO:0044215) other organism cell(GO:0044216) other organism part(GO:0044217)
0.0 3.9 GO:0036126 sperm flagellum(GO:0036126)
0.0 2.9 GO:0043198 dendritic shaft(GO:0043198)
0.0 3.2 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.0 39.9 GO:0031410 cytoplasmic vesicle(GO:0031410)
0.0 2.7 GO:0001650 fibrillar center(GO:0001650)
0.0 1.2 GO:0005811 lipid particle(GO:0005811)
0.0 6.7 GO:0005667 transcription factor complex(GO:0005667)
0.0 1.9 GO:0005923 bicellular tight junction(GO:0005923)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.4 4.1 GO:0004373 glycogen (starch) synthase activity(GO:0004373)
1.3 7.7 GO:0004748 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
1.1 7.9 GO:0052798 beta-galactoside alpha-2,3-sialyltransferase activity(GO:0052798)
1.0 3.1 GO:0017084 glutamate 5-kinase activity(GO:0004349) glutamate-5-semialdehyde dehydrogenase activity(GO:0004350) delta1-pyrroline-5-carboxylate synthetase activity(GO:0017084) amino acid kinase activity(GO:0019202)
0.7 2.1 GO:0019959 interleukin-8 binding(GO:0019959)
0.6 10.1 GO:0019841 retinol binding(GO:0019841)
0.5 4.2 GO:0008865 fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.4 2.4 GO:0060230 lipoprotein lipase activator activity(GO:0060230)
0.4 1.1 GO:0036461 BLOC-2 complex binding(GO:0036461)
0.3 3.6 GO:0070087 chromo shadow domain binding(GO:0070087)
0.3 2.2 GO:0047179 platelet-activating factor acetyltransferase activity(GO:0047179)
0.3 2.9 GO:0016861 intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.3 14.5 GO:0008536 Ran GTPase binding(GO:0008536)
0.2 0.7 GO:0001042 RNA polymerase I core binding(GO:0001042)
0.2 0.7 GO:0035500 MH2 domain binding(GO:0035500)
0.2 1.4 GO:0031812 G-protein coupled nucleotide receptor binding(GO:0031811) P2Y1 nucleotide receptor binding(GO:0031812)
0.2 2.1 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
0.2 2.1 GO:0031802 type 5 metabotropic glutamate receptor binding(GO:0031802)
0.1 8.6 GO:0070888 bHLH transcription factor binding(GO:0043425) E-box binding(GO:0070888)
0.1 13.3 GO:0003730 mRNA 3'-UTR binding(GO:0003730)
0.1 1.4 GO:0017162 aryl hydrocarbon receptor binding(GO:0017162)
0.1 2.2 GO:0003746 translation elongation factor activity(GO:0003746)
0.1 0.3 GO:0003976 UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity(GO:0003976)
0.1 0.8 GO:0004526 ribonuclease P activity(GO:0004526)
0.1 0.2 GO:0031531 thyrotropin-releasing hormone receptor binding(GO:0031531)
0.1 0.9 GO:0017151 DEAD/H-box RNA helicase binding(GO:0017151)
0.1 0.5 GO:0031013 troponin I binding(GO:0031013)
0.1 1.9 GO:0005540 hyaluronic acid binding(GO:0005540)
0.1 0.9 GO:0042834 peptidoglycan binding(GO:0042834)
0.1 1.6 GO:0001222 transcription corepressor binding(GO:0001222)
0.1 1.2 GO:0051011 microtubule minus-end binding(GO:0051011)
0.1 0.3 GO:0022850 serotonin-gated cation channel activity(GO:0022850)
0.1 7.4 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.1 0.6 GO:0005127 ciliary neurotrophic factor receptor binding(GO:0005127)
0.1 0.4 GO:0048019 receptor antagonist activity(GO:0048019)
0.0 0.5 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.0 3.3 GO:0019843 rRNA binding(GO:0019843)
0.0 0.7 GO:0043008 ATP-dependent protein binding(GO:0043008)
0.0 0.2 GO:0005134 interleukin-2 receptor binding(GO:0005134)
0.0 1.7 GO:0017134 fibroblast growth factor binding(GO:0017134)
0.0 1.5 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 4.6 GO:0051082 unfolded protein binding(GO:0051082)
0.0 0.9 GO:0017160 Ral GTPase binding(GO:0017160)
0.0 0.4 GO:0031852 mu-type opioid receptor binding(GO:0031852)
0.0 1.9 GO:0008374 O-acyltransferase activity(GO:0008374)
0.0 0.5 GO:0005132 type I interferon receptor binding(GO:0005132)
0.0 0.2 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.0 0.2 GO:1990380 Lys48-specific deubiquitinase activity(GO:1990380)
0.0 0.7 GO:0051059 NF-kappaB binding(GO:0051059)
0.0 2.4 GO:0003735 structural constituent of ribosome(GO:0003735)
0.0 1.5 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.0 0.5 GO:0008198 ferrous iron binding(GO:0008198)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 11.5 PID AURORA A PATHWAY Aurora A signaling
0.1 1.9 ST JAK STAT PATHWAY Jak-STAT Pathway
0.1 4.1 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.1 7.7 PID E2F PATHWAY E2F transcription factor network
0.1 9.3 PID RB 1PATHWAY Regulation of retinoblastoma protein
0.1 2.3 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.1 3.3 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.0 2.1 ST GRANULE CELL SURVIVAL PATHWAY Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.0 1.6 PID BARD1 PATHWAY BARD1 signaling events
0.0 1.4 ST GA12 PATHWAY G alpha 12 Pathway
0.0 1.5 ST JNK MAPK PATHWAY JNK MAPK Pathway
0.0 1.5 NABA COLLAGENS Genes encoding collagen proteins
0.0 0.4 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.0 0.3 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.0 0.9 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.0 0.7 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 7.7 REACTOME G1 S SPECIFIC TRANSCRIPTION Genes involved in G1/S-Specific Transcription
0.3 7.9 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.2 9.3 REACTOME METABOLISM OF STEROID HORMONES AND VITAMINS A AND D Genes involved in Metabolism of steroid hormones and vitamins A and D
0.1 1.7 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.1 2.4 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.1 3.6 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.1 3.1 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.1 11.9 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.1 2.1 REACTOME PYRUVATE METABOLISM Genes involved in Pyruvate metabolism
0.1 3.2 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.1 5.0 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.1 1.6 REACTOME FANCONI ANEMIA PATHWAY Genes involved in Fanconi Anemia pathway
0.0 1.5 REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR Genes involved in Signaling by constitutively active EGFR
0.0 2.1 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 0.9 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 2.4 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.0 0.7 REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS Genes involved in Trafficking of GluR2-containing AMPA receptors
0.0 2.2 REACTOME TRANSLATION Genes involved in Translation
0.0 1.4 REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.0 2.6 REACTOME GLUCOSE METABOLISM Genes involved in Glucose metabolism
0.0 1.5 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 0.5 REACTOME REGULATION OF IFNA SIGNALING Genes involved in Regulation of IFNA signaling
0.0 0.4 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events