ISMARA results: Nkx6-1_Evx1

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GSE58827: Dynamics of the Mouse Liver

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Results for Nkx6-1_Evx1_Hesx1

Z-value: 0.72

Motif logo

Transcription factors associated with Nkx6-1_Evx1_Hesx1

Gene Symbol	Gene ID	Gene Info
Nkx6-1 Ensembl NCBI MGI UniProt	ENSMUSG00000035187.11	NK6 homeobox 1
Evx1 Ensembl NCBI MGI UniProt	ENSMUSG00000005503.9	even-skipped homeobox 1
Hesx1 Ensembl NCBI MGI UniProt	ENSMUSG00000040726.11	homeobox gene expressed in ES cells

Activity-expression correlation:

Gene	Promoter	Pearson corr. coef.	P-value	Plot
Hesx1	mm39_v1_chr14_+_26722319_26722463	0.84	1.7e-10	Click!
Nkx6-1	mm39_v1_chr5_-_101812862_101812862	0.24	1.7e-01	Click!

Activity profile of Nkx6-1_Evx1_Hesx1 motif

Sorted Z-values of Nkx6-1_Evx1_Hesx1 motif

Top targets:

Promoter	Log-likelihood	Transcript	Gene	Gene Info
chr2_+_174292471 Show fit	6.68	ENSMUST00000016399.6	Tubb1 Ensembl NCBI MGI UniProt Show fit	tubulin, beta 1 class VI
chr2_+_84564394 Show fit	6.12	ENSMUST00000238573.2 ENSMUST00000090729.9	Ypel4 Ensembl NCBI MGI UniProt Show fit	yippee like 4
chrX_+_55500170 Show fit	5.97	ENSMUST00000039374.9 ENSMUST00000101553.9 ENSMUST00000186445.7	Ints6l Ensembl NCBI MGI UniProt Show fit	integrator complex subunit 6 like
chr6_+_125529911 Show fit	5.22	ENSMUST00000112254.8 ENSMUST00000112253.6	Vwf Ensembl NCBI MGI UniProt Show fit	Von Willebrand factor
chr1_-_132318039 Show fit	4.73	ENSMUST00000132435.2	Tmcc2 Ensembl NCBI MGI UniProt Show fit	transmembrane and coiled-coil domains 2
chr3_+_54268523 Show fit	4.30	ENSMUST00000117373.8 ENSMUST00000107985.10 ENSMUST00000073012.13 ENSMUST00000081564.13	Postn Ensembl NCBI MGI UniProt Show fit	periostin, osteoblast specific factor
chr9_+_65797519 Show fit	4.12	ENSMUST00000045802.7	Pclaf Ensembl NCBI MGI UniProt Show fit	PCNA clamp associated factor
chr6_-_56900917 Show fit	3.89	ENSMUST00000031793.8	Nt5c3 Ensembl NCBI MGI UniProt Show fit	5'-nucleotidase, cytosolic III
chr14_+_26722319 Show fit	3.60	ENSMUST00000035433.10	Hesx1 Ensembl NCBI MGI UniProt Show fit	homeobox gene expressed in ES cells
chr18_-_43610829 Show fit	3.57	ENSMUST00000057110.11	Eif3j2 Ensembl NCBI MGI UniProt Show fit	eukaryotic translation initiation factor 3, subunit J2
chr5_+_33815466 Show fit	3.36	ENSMUST00000074849.13 ENSMUST00000079534.11 ENSMUST00000201633.2	Tacc3 Ensembl NCBI MGI UniProt Show fit	transforming, acidic coiled-coil containing protein 3
chr3_-_130524024 Show fit	3.27	ENSMUST00000079085.11	Rpl34 Ensembl NCBI MGI UniProt Show fit	ribosomal protein L34
chr6_+_121613177 Show fit	3.18	ENSMUST00000032203.9	A2m Ensembl NCBI MGI UniProt Show fit	alpha-2-macroglobulin
chr9_+_113641615 Show fit	3.13	ENSMUST00000111838.10 ENSMUST00000166734.10 ENSMUST00000214522.2 ENSMUST00000163895.3	Clasp2 Ensembl NCBI MGI UniProt Show fit	CLIP associating protein 2
chr10_+_75399920 Show fit	3.00	ENSMUST00000141062.8 ENSMUST00000152657.8	Ggt1 Ensembl NCBI MGI UniProt Show fit	gamma-glutamyltransferase 1
chr19_+_45433899 Show fit	2.97	ENSMUST00000224478.2	Btrc Ensembl NCBI MGI UniProt Show fit	beta-transducin repeat containing protein
chr11_+_11634967 Show fit	2.86	ENSMUST00000141436.8 ENSMUST00000126058.8	Ikzf1 Ensembl NCBI MGI UniProt Show fit	IKAROS family zinc finger 1
chr17_+_41121979 Show fit	2.86	ENSMUST00000024721.8 ENSMUST00000233740.2	Rhag Ensembl NCBI MGI UniProt Show fit	Rhesus blood group-associated A glycoprotein
chr19_-_46033353 Show fit	2.85	ENSMUST00000026252.14 ENSMUST00000156585.9 ENSMUST00000185355.7 ENSMUST00000152946.8	Ldb1 Ensembl NCBI MGI UniProt Show fit	LIM domain binding 1
chr2_-_153079828 Show fit	2.84	ENSMUST00000109795.2	Plagl2 Ensembl NCBI MGI UniProt Show fit	pleiomorphic adenoma gene-like 2
chr15_+_6673167 Show fit	2.82	ENSMUST00000163073.2	Fyb Ensembl NCBI MGI UniProt Show fit	FYN binding protein
chr4_+_34893772 Show fit	2.79	ENSMUST00000029975.10 ENSMUST00000135871.8 ENSMUST00000108130.2	Cga Ensembl NCBI MGI UniProt Show fit	glycoprotein hormones, alpha subunit
chr8_+_23525101 Show fit	2.68	ENSMUST00000117662.8 ENSMUST00000117296.8 ENSMUST00000141784.9	Ank1 Ensembl NCBI MGI UniProt Show fit	ankyrin 1, erythroid
chr6_-_116693849 Show fit	2.65	ENSMUST00000056623.13	Tmem72 Ensembl NCBI MGI UniProt Show fit	transmembrane protein 72
chr6_-_136758716 Show fit	2.45	ENSMUST00000078095.11 ENSMUST00000032338.10	Gucy2c Ensembl NCBI MGI UniProt Show fit	guanylate cyclase 2c
chr12_+_108572015 Show fit	2.43	ENSMUST00000109854.9	Evl Ensembl NCBI MGI UniProt Show fit	Ena-vasodilator stimulated phosphoprotein
chr8_+_23901506 Show fit	2.40	ENSMUST00000033952.8	Sfrp1 Ensembl NCBI MGI UniProt Show fit	secreted frizzled-related protein 1
chr6_+_71886030 Show fit	2.36	ENSMUST00000055296.11	Polr1a Ensembl NCBI MGI UniProt Show fit	polymerase (RNA) I polypeptide A
chr5_+_117378510 Show fit	2.35	ENSMUST00000111975.3	Taok3 Ensembl NCBI MGI UniProt Show fit	TAO kinase 3
chr10_+_79650496 Show fit	2.30	ENSMUST00000218857.2 ENSMUST00000220365.2	Palm Ensembl NCBI MGI UniProt Show fit	paralemmin
chr2_+_124910037 Show fit	2.25	ENSMUST00000070353.4	Slc24a5 Ensembl NCBI MGI UniProt Show fit	solute carrier family 24, member 5
chr19_+_34078333 Show fit	2.25	ENSMUST00000025685.8	Lipm Ensembl NCBI MGI UniProt Show fit	lipase, family member M
chr17_+_46471950 Show fit	2.23	ENSMUST00000024748.14 ENSMUST00000172170.8	Gtpbp2 Ensembl NCBI MGI UniProt Show fit	GTP binding protein 2
chr5_+_35156389 Show fit	2.18	ENSMUST00000114281.8 ENSMUST00000114280.8	Rgs12 Ensembl NCBI MGI UniProt Show fit	regulator of G-protein signaling 12
chr1_+_82817794 Show fit	2.17	ENSMUST00000186043.2	Agfg1 Ensembl NCBI MGI UniProt Show fit	ArfGAP with FG repeats 1
chr7_+_121758646 Show fit	2.13	ENSMUST00000033154.8 ENSMUST00000205901.2	Plk1 Ensembl NCBI MGI UniProt Show fit	polo like kinase 1
chr2_-_151586063 Show fit	2.09	ENSMUST00000109869.2	Psmf1 Ensembl NCBI MGI UniProt Show fit	proteasome (prosome, macropain) inhibitor subunit 1
chr18_+_42669322 Show fit	2.08	ENSMUST00000236418.2	Tcerg1 Ensembl NCBI MGI UniProt Show fit	transcription elongation regulator 1 (CA150)
chr6_+_83142902 Show fit	2.06	ENSMUST00000077407.12 ENSMUST00000113913.8 ENSMUST00000130212.8	Dctn1 Ensembl NCBI MGI UniProt Show fit	dynactin 1
chr4_+_114914880 Show fit	2.06	ENSMUST00000161601.8	Tal1 Ensembl NCBI MGI UniProt Show fit	T cell acute lymphocytic leukemia 1
chr3_-_88317601 Show fit	2.06	ENSMUST00000193338.6 ENSMUST00000056370.13	Pmf1 Ensembl NCBI MGI UniProt Show fit	polyamine-modulated factor 1
chr2_+_36120438 Show fit	2.04	ENSMUST00000062069.6	Ptgs1 Ensembl NCBI MGI UniProt Show fit	prostaglandin-endoperoxide synthase 1
chr9_+_96140781 Show fit	2.03	ENSMUST00000190104.7 ENSMUST00000179416.8 ENSMUST00000189606.7	Tfdp2 Ensembl NCBI MGI UniProt Show fit	transcription factor Dp 2
chr3_-_129834788 Show fit	2.02	ENSMUST00000168644.3	Sec24b Ensembl NCBI MGI UniProt Show fit	Sec24 related gene family, member B (S. cerevisiae)
chrX_+_162873183 Show fit	1.93	ENSMUST00000015545.10	Cltrn Ensembl NCBI MGI UniProt Show fit	collectrin, amino acid transport regulator
chr4_-_87724533 Show fit	1.90	ENSMUST00000126353.8 ENSMUST00000149357.8	Mllt3 Ensembl NCBI MGI UniProt Show fit	myeloid/lymphoid or mixed-lineage leukemia; translocated to, 3
chr13_+_117356808 Show fit	1.85	ENSMUST00000022242.9	Emb Ensembl NCBI MGI UniProt Show fit	embigin
chr8_+_107757847 Show fit	1.85	ENSMUST00000034388.10	Vps4a Ensembl NCBI MGI UniProt Show fit	vacuolar protein sorting 4A
chr9_-_20871081 Show fit	1.84	ENSMUST00000177754.9	Dnmt1 Ensembl NCBI MGI UniProt Show fit	DNA methyltransferase (cytosine-5) 1
chr9_+_96140750 Show fit	1.83	ENSMUST00000186609.7	Tfdp2 Ensembl NCBI MGI UniProt Show fit	transcription factor Dp 2
chr3_+_159545309 Show fit	1.83	ENSMUST00000068952.10 ENSMUST00000198878.2	Wls Ensembl NCBI MGI UniProt Show fit	wntless WNT ligand secretion mediator
chr9_+_118892497 Show fit	1.82	ENSMUST00000141185.8 ENSMUST00000126251.8 ENSMUST00000136561.2	Vill Ensembl NCBI MGI UniProt Show fit	villin-like
chrX_+_149330371 Show fit	1.80	ENSMUST00000066337.13 ENSMUST00000112715.2	Alas2 Ensembl NCBI MGI UniProt Show fit	aminolevulinic acid synthase 2, erythroid
chrX_-_101200670 Show fit	1.78	ENSMUST00000056904.3	Ercc6l Ensembl NCBI MGI UniProt Show fit	excision repair cross-complementing rodent repair deficiency complementation group 6 like
chr7_+_110371811 Show fit	1.77	ENSMUST00000005829.13	Ampd3 Ensembl NCBI MGI UniProt Show fit	adenosine monophosphate deaminase 3
chr1_+_107456731 Show fit	1.72	ENSMUST00000182198.8	Serpinb10 Ensembl NCBI MGI UniProt Show fit	serine (or cysteine) peptidase inhibitor, clade B (ovalbumin), member 10
chr6_+_57679455 Show fit	1.69	ENSMUST00000072954.8	Lancl2 Ensembl NCBI MGI UniProt Show fit	LanC (bacterial lantibiotic synthetase component C)-like 2
chr5_-_138169509 Show fit	1.68	ENSMUST00000153867.8	Mcm7 Ensembl NCBI MGI UniProt Show fit	minichromosome maintenance complex component 7
chr7_-_115459082 Show fit	1.66	ENSMUST00000206123.2	Sox6 Ensembl NCBI MGI UniProt Show fit	SRY (sex determining region Y)-box 6
chr13_-_22017677 Show fit	1.65	ENSMUST00000081342.7	H2ac24 Ensembl NCBI MGI UniProt Show fit	H2A clustered histone 24
chr1_-_134883645 Show fit	1.63	ENSMUST00000045665.13 ENSMUST00000086444.6 ENSMUST00000112163.2	Ppp1r12b Ensembl NCBI MGI UniProt Show fit	protein phosphatase 1, regulatory subunit 12B
chr4_+_19818718 Show fit	1.63	ENSMUST00000035890.8	Slc7a13 Ensembl NCBI MGI UniProt Show fit	solute carrier family 7, (cationic amino acid transporter, y+ system) member 13
chr5_-_138169253 Show fit	1.60	ENSMUST00000139983.8	Mcm7 Ensembl NCBI MGI UniProt Show fit	minichromosome maintenance complex component 7
chr3_-_116047148 Show fit	1.59	ENSMUST00000090473.7	Gpr88 Ensembl NCBI MGI UniProt Show fit	G-protein coupled receptor 88
chr4_+_98812047 Show fit	1.58	ENSMUST00000030289.9	Usp1 Ensembl NCBI MGI UniProt Show fit	ubiquitin specific peptidase 1
chrX_+_164953444 Show fit	1.55	ENSMUST00000130880.9 ENSMUST00000056410.11 ENSMUST00000096252.10 ENSMUST00000087169.11	Gemin8 Ensembl NCBI MGI UniProt Show fit	gem nuclear organelle associated protein 8
chr18_+_23885390 Show fit	1.53	ENSMUST00000170802.8 ENSMUST00000155708.8 ENSMUST00000118826.9	Mapre2 Ensembl NCBI MGI UniProt Show fit	microtubule-associated protein, RP/EB family, member 2
chr10_-_129107354 Show fit	1.52	ENSMUST00000204573.3	Olfr777 Ensembl NCBI MGI UniProt Show fit	olfactory receptor 777
chr17_+_71326510 Show fit	1.52	ENSMUST00000073211.13 ENSMUST00000024847.14	Myom1 Ensembl NCBI MGI UniProt Show fit	myomesin 1
chr6_+_136509922 Show fit	1.51	ENSMUST00000187429.4	Atf7ip Ensembl NCBI MGI UniProt Show fit	activating transcription factor 7 interacting protein
chr14_-_86986541 Show fit	1.51	ENSMUST00000226254.2	Diaph3 Ensembl NCBI MGI UniProt Show fit	diaphanous related formin 3
chr1_+_40554513 Show fit	1.51	ENSMUST00000027237.12	Il18rap Ensembl NCBI MGI UniProt Show fit	interleukin 18 receptor accessory protein
chrX_+_139857640 Show fit	1.50	ENSMUST00000112971.2	Atg4a Ensembl NCBI MGI UniProt Show fit	autophagy related 4A, cysteine peptidase
chr14_-_67246282 Show fit	1.49	ENSMUST00000111115.8 ENSMUST00000022634.9	Bnip3l Ensembl NCBI MGI UniProt Show fit	BCL2/adenovirus E1B interacting protein 3-like
chr2_-_58050494 Show fit	1.49	ENSMUST00000028175.7	Cytip Ensembl NCBI MGI UniProt Show fit	cytohesin 1 interacting protein
chrX_-_138772383 Show fit	1.48	ENSMUST00000033811.14 ENSMUST00000087401.12	Morc4 Ensembl NCBI MGI UniProt Show fit	microrchidia 4
chr16_-_42160957 Show fit	1.44	ENSMUST00000102817.5	Gap43 Ensembl NCBI MGI UniProt Show fit	growth associated protein 43
chr14_-_49482846 Show fit	1.43	ENSMUST00000227113.2 ENSMUST00000130853.2 ENSMUST00000228936.2 ENSMUST00000022398.15	ccdc198 Ensembl NCBI MGI UniProt Show fit	coiled-coil domain containing 198
chr6_+_57679621 Show fit	1.43	ENSMUST00000050077.15	Lancl2 Ensembl NCBI MGI UniProt Show fit	LanC (bacterial lantibiotic synthetase component C)-like 2
chrX_-_149372840 Show fit	1.42	ENSMUST00000112725.8 ENSMUST00000112720.8	Apex2 Ensembl NCBI MGI UniProt Show fit	apurinic/apyrimidinic endonuclease 2
chr14_+_79753055 Show fit	1.40	ENSMUST00000110835.3 ENSMUST00000227192.2	Elf1 Ensembl NCBI MGI UniProt Show fit	E74-like factor 1
chr9_+_38766356 Show fit	1.37	ENSMUST00000104874.3	Olfr26 Ensembl NCBI MGI UniProt Show fit	olfactory receptor 26
chr15_+_103148824 Show fit	1.35	ENSMUST00000036004.16 ENSMUST00000087351.9 ENSMUST00000231141.2	Hnrnpa1 Ensembl NCBI MGI UniProt Show fit	heterogeneous nuclear ribonucleoprotein A1
chr9_+_38788422 Show fit	1.34	ENSMUST00000078289.3	Olfr926 Ensembl NCBI MGI UniProt Show fit	olfactory receptor 926
chr14_+_19801333 Show fit	1.34	ENSMUST00000022340.5	Nid2 Ensembl NCBI MGI UniProt Show fit	nidogen 2
chr15_-_100322934 Show fit	1.33	ENSMUST00000123461.8	Slc11a2 Ensembl NCBI MGI UniProt Show fit	solute carrier family 11 (proton-coupled divalent metal ion transporters), member 2
chr11_+_31823096 Show fit	1.33	ENSMUST00000155278.2	Cpeb4 Ensembl NCBI MGI UniProt Show fit	cytoplasmic polyadenylation element binding protein 4
chr5_-_65855511 Show fit	1.33	ENSMUST00000201948.4	Pds5a Ensembl NCBI MGI UniProt Show fit	PDS5 cohesin associated factor A
chr9_+_108437485 Show fit	1.32	ENSMUST00000081111.14 ENSMUST00000193421.2	Impdh2 Ensembl NCBI MGI UniProt Show fit	inosine monophosphate dehydrogenase 2
chr10_-_25076008 Show fit	1.32	ENSMUST00000100012.3	Akap7 Ensembl NCBI MGI UniProt Show fit	A kinase (PRKA) anchor protein 7
chr11_-_106205320 Show fit	1.31	ENSMUST00000167143.2	Cd79b Ensembl NCBI MGI UniProt Show fit	CD79B antigen
chr2_+_79085844 Show fit	1.29	ENSMUST00000099972.5	Itga4 Ensembl NCBI MGI UniProt Show fit	integrin alpha 4
chr2_-_168608949 Show fit	1.28	ENSMUST00000075044.10	Sall4 Ensembl NCBI MGI UniProt Show fit	spalt like transcription factor 4
chr5_-_116162415 Show fit	1.28	ENSMUST00000031486.14 ENSMUST00000111999.8	Prkab1 Ensembl NCBI MGI UniProt Show fit	protein kinase, AMP-activated, beta 1 non-catalytic subunit
chrX_+_139857688 Show fit	1.28	ENSMUST00000239541.1	Atg4a Ensembl NCBI MGI UniProt Show fit	autophagy related 4A, cysteine peptidase
chr17_-_26420300 Show fit	1.28	ENSMUST00000025019.9	Arhgdig Ensembl NCBI MGI UniProt Show fit	Rho GDP dissociation inhibitor (GDI) gamma
chr1_-_45542442 Show fit	1.27	ENSMUST00000086430.5	Col5a2 Ensembl NCBI MGI UniProt Show fit	collagen, type V, alpha 2
chr11_-_107228382 Show fit	1.26	ENSMUST00000040380.13	Pitpnc1 Ensembl NCBI MGI UniProt Show fit	phosphatidylinositol transfer protein, cytoplasmic 1
chr1_-_182929025 Show fit	1.26	ENSMUST00000171366.7	Disp1 Ensembl NCBI MGI UniProt Show fit	dispatched RND transporter family member 1
chr4_-_131802561 Show fit	1.26	ENSMUST00000105970.8 ENSMUST00000105975.8	Epb41 Ensembl NCBI MGI UniProt Show fit	erythrocyte membrane protein band 4.1
chr2_+_4022537 Show fit	1.26	ENSMUST00000177457.8	Frmd4a Ensembl NCBI MGI UniProt Show fit	FERM domain containing 4A
chr2_+_84818538 Show fit	1.23	ENSMUST00000028466.12	Prg3 Ensembl NCBI MGI UniProt Show fit	proteoglycan 3
chr5_+_35156454 Show fit	1.22	ENSMUST00000114283.8	Rgs12 Ensembl NCBI MGI UniProt Show fit	regulator of G-protein signaling 12
chr7_+_126376099 Show fit	1.21	ENSMUST00000038614.12 ENSMUST00000170882.8 ENSMUST00000106359.2 ENSMUST00000106357.8 ENSMUST00000145762.8	Ypel3 Ensembl NCBI MGI UniProt Show fit	yippee like 3
chr15_-_100322089 Show fit	1.21	ENSMUST00000154331.2	Slc11a2 Ensembl NCBI MGI UniProt Show fit	solute carrier family 11 (proton-coupled divalent metal ion transporters), member 2
chr17_-_37523969 Show fit	1.20	ENSMUST00000060728.7 ENSMUST00000216318.2	Olfr95 Ensembl NCBI MGI UniProt Show fit	olfactory receptor 95
chr4_-_43499608 Show fit	1.20	ENSMUST00000136005.3 ENSMUST00000054538.13	Arhgef39 Ensembl NCBI MGI UniProt Show fit	Rho guanine nucleotide exchange factor (GEF) 39
chr11_-_96859484 Show fit	1.19	ENSMUST00000107623.8	Sp2 Ensembl NCBI MGI UniProt Show fit	Sp2 transcription factor
chr2_+_152596075 Show fit	1.19	ENSMUST00000010020.12	Cox4i2 Ensembl NCBI MGI UniProt Show fit	cytochrome c oxidase subunit 4I2
chr2_-_111843053 Show fit	1.19	ENSMUST00000213559.3	Olfr1310 Ensembl NCBI MGI UniProt Show fit	olfactory receptor 1310
chr4_-_43710231 Show fit	1.17	ENSMUST00000217544.2 ENSMUST00000107862.3	Olfr71 Ensembl NCBI MGI UniProt Show fit	olfactory receptor 71
chr10_-_23977810 Show fit	1.16	ENSMUST00000170267.3	Taar8c Ensembl NCBI MGI UniProt Show fit	trace amine-associated receptor 8C
chrX_+_47235313 Show fit	1.16	ENSMUST00000033427.7	Sash3 Ensembl NCBI MGI UniProt Show fit	SAM and SH3 domain containing 3
chr19_+_13208692 Show fit	1.15	ENSMUST00000207246.4	Olfr1463 Ensembl NCBI MGI UniProt Show fit	olfactory receptor 1463
chr12_-_55061117 Show fit	1.15	ENSMUST00000172875.8	Baz1a Ensembl NCBI MGI UniProt Show fit	bromodomain adjacent to zinc finger domain 1A
chr1_+_139382485 Show fit	1.15	ENSMUST00000200083.5 ENSMUST00000053364.12	Aspm Ensembl NCBI MGI UniProt Show fit	abnormal spindle microtubule assembly
chr13_+_21363602 Show fit	1.14	ENSMUST00000222544.2	Trim27 Ensembl NCBI MGI UniProt Show fit	tripartite motif-containing 27
chr11_+_120499295 Show fit	1.14	ENSMUST00000106194.8 ENSMUST00000106195.3 ENSMUST00000061309.5	Npb Ensembl NCBI MGI UniProt Show fit	neuropeptide B
chr3_-_130523954 Show fit	1.13	ENSMUST00000196202.5 ENSMUST00000133802.6 ENSMUST00000062601.14 ENSMUST00000200517.2	Rpl34 Ensembl NCBI MGI UniProt Show fit	ribosomal protein L34
chr10_+_58230203 Show fit	1.11	ENSMUST00000105468.2	Lims1 Ensembl NCBI MGI UniProt Show fit	LIM and senescent cell antigen-like domains 1
chr12_-_111780268 Show fit	1.11	ENSMUST00000021715.6	Xrcc3 Ensembl NCBI MGI UniProt Show fit	X-ray repair complementing defective repair in Chinese hamster cells 3
chr10_+_94411119 Show fit	1.11	ENSMUST00000121471.8	Tmcc3 Ensembl NCBI MGI UniProt Show fit	transmembrane and coiled coil domains 3
chr4_-_131802606 Show fit	1.10	ENSMUST00000146021.8	Epb41 Ensembl NCBI MGI UniProt Show fit	erythrocyte membrane protein band 4.1
chr12_-_55033130 Show fit	1.09	ENSMUST00000173433.8 ENSMUST00000173803.2	Baz1a Ensembl NCBI MGI UniProt Show fit Gm20403 Ensembl NCBI MGI UniProt Show fit	bromodomain adjacent to zinc finger domain 1A predicted gene 20403
chr2_-_119985078 Show fit	1.09	ENSMUST00000028755.8	Ehd4 Ensembl NCBI MGI UniProt Show fit	EH-domain containing 4
chr3_-_14873406 Show fit	1.09	ENSMUST00000181860.8 ENSMUST00000144327.3	Car1 Ensembl NCBI MGI UniProt Show fit	carbonic anhydrase 1
chrX_+_158086253 Show fit	1.09	ENSMUST00000112491.2	Rps6ka3 Ensembl NCBI MGI UniProt Show fit	ribosomal protein S6 kinase polypeptide 3
chr17_-_26420332 Show fit	1.09	ENSMUST00000121959.3	Arhgdig Ensembl NCBI MGI UniProt Show fit	Rho GDP dissociation inhibitor (GDI) gamma
chr3_-_14843512 Show fit	1.08	ENSMUST00000094365.11	Car1 Ensembl NCBI MGI UniProt Show fit	carbonic anhydrase 1
chr2_+_163535925 Show fit	1.08	ENSMUST00000109400.3	Pkig Ensembl NCBI MGI UniProt Show fit	protein kinase inhibitor, gamma
chr17_+_21031817 Show fit	1.07	ENSMUST00000232810.2 ENSMUST00000233712.2 ENSMUST00000232852.2	Vmn1r229 Ensembl NCBI MGI UniProt Show fit	vomeronasal 1 receptor 229
chr14_-_70945434 Show fit	1.04	ENSMUST00000228346.2	Xpo7 Ensembl NCBI MGI UniProt Show fit	exportin 7
chr2_-_30720345 Show fit	1.04	ENSMUST00000041726.4	Asb6 Ensembl NCBI MGI UniProt Show fit	ankyrin repeat and SOCS box-containing 6
chr10_+_58230183 Show fit	1.03	ENSMUST00000020077.11	Lims1 Ensembl NCBI MGI UniProt Show fit	LIM and senescent cell antigen-like domains 1
chr17_+_71326542 Show fit	1.03	ENSMUST00000179759.3	Myom1 Ensembl NCBI MGI UniProt Show fit	myomesin 1
chrX_+_158623460 Show fit	1.03	ENSMUST00000112451.8 ENSMUST00000112453.9	Sh3kbp1 Ensembl NCBI MGI UniProt Show fit	SH3-domain kinase binding protein 1
chr8_-_3675274 Show fit	1.03	ENSMUST00000004749.7	Pcp2 Ensembl NCBI MGI UniProt Show fit	Purkinje cell protein 2 (L7)
chr8_-_62576140 Show fit	1.02	ENSMUST00000034052.14 ENSMUST00000034054.9	Anxa10 Ensembl NCBI MGI UniProt Show fit	annexin A10
chr15_-_66684442 Show fit	1.02	ENSMUST00000100572.10	Sla Ensembl NCBI MGI UniProt Show fit	src-like adaptor
chr5_+_103902426 Show fit	1.02	ENSMUST00000153165.8 ENSMUST00000031256.6	Aff1 Ensembl NCBI MGI UniProt Show fit	AF4/FMR2 family, member 1
chr3_+_121838076 Show fit	1.01	ENSMUST00000013995.13	Abca4 Ensembl NCBI MGI UniProt Show fit	ATP-binding cassette, sub-family A (ABC1), member 4
chr19_-_24178000 Show fit	1.01	ENSMUST00000233658.3	Tjp2 Ensembl NCBI MGI UniProt Show fit	tight junction protein 2
chr9_+_19828161 Show fit	1.00	ENSMUST00000217347.2 ENSMUST00000057596.10	Olfr77 Ensembl NCBI MGI UniProt Show fit	olfactory receptor 77
chr10_+_127257077 Show fit	1.00	ENSMUST00000168780.8	R3hdm2 Ensembl NCBI MGI UniProt Show fit	R3H domain containing 2
chr5_-_137530214 Show fit	1.00	ENSMUST00000140139.2	Gnb2 Ensembl NCBI MGI UniProt Show fit	guanine nucleotide binding protein (G protein), beta 2
chr19_+_12647803 Show fit	0.99	ENSMUST00000207341.3 ENSMUST00000208494.3 ENSMUST00000208657.3	Olfr1442 Ensembl NCBI MGI UniProt Show fit	olfactory receptor 1442
chr9_+_62765362 Show fit	0.98	ENSMUST00000213643.2 ENSMUST00000034777.14 ENSMUST00000163820.3 ENSMUST00000215870.2 ENSMUST00000214633.2 ENSMUST00000215968.2	Calml4 Ensembl NCBI MGI UniProt Show fit	calmodulin-like 4
chr7_-_45480200 Show fit	0.98	ENSMUST00000107723.9 ENSMUST00000131384.3	Grwd1 Ensembl NCBI MGI UniProt Show fit	glutamate-rich WD repeat containing 1
chr16_+_33614378 Show fit	0.98	ENSMUST00000115044.8	Muc13 Ensembl NCBI MGI UniProt Show fit	mucin 13, epithelial transmembrane
chr13_-_97897139 Show fit	0.97	ENSMUST00000074072.5	Rps18-ps6 Ensembl NCBI MGI UniProt Show fit	ribosomal protein S18, pseudogene 6
chr2_-_86109346 Show fit	0.97	ENSMUST00000217294.2 ENSMUST00000217245.2 ENSMUST00000216432.2	Olfr1051 Ensembl NCBI MGI UniProt Show fit	olfactory receptor 1051
chr6_-_30936013 Show fit	0.97	ENSMUST00000101589.5	Klf14 Ensembl NCBI MGI UniProt Show fit	Kruppel-like factor 14
chr1_+_156193607 Show fit	0.97	ENSMUST00000102782.4	Gm2000 Ensembl NCBI MGI UniProt Show fit	predicted gene 2000
chr12_+_117807224 Show fit	0.96	ENSMUST00000021592.16	Cdca7l Ensembl NCBI MGI UniProt Show fit	cell division cycle associated 7 like
chr5_+_66833434 Show fit	0.96	ENSMUST00000031131.11	Uchl1 Ensembl NCBI MGI UniProt Show fit	ubiquitin carboxy-terminal hydrolase L1
chr2_-_5838489 Show fit	0.96	ENSMUST00000128467.4	Cdc123 Ensembl NCBI MGI UniProt Show fit	cell division cycle 123
chr11_+_98689479 Show fit	0.94	ENSMUST00000037930.13	Msl1 Ensembl NCBI MGI UniProt Show fit	male specific lethal 1
chr2_-_168609110 Show fit	0.94	ENSMUST00000029061.12 ENSMUST00000103074.2	Sall4 Ensembl NCBI MGI UniProt Show fit	spalt like transcription factor 4
chr4_+_103000248 Show fit	0.93	ENSMUST00000106855.2	Mier1 Ensembl NCBI MGI UniProt Show fit	MEIR1 treanscription regulator
chr2_+_85838122 Show fit	0.93	ENSMUST00000062166.2	Olfr1032 Ensembl NCBI MGI UniProt Show fit	olfactory receptor 1032
chr9_+_56325893 Show fit	0.91	ENSMUST00000034879.5 ENSMUST00000215269.2	Hmg20a Ensembl NCBI MGI UniProt Show fit	high mobility group 20A
chr6_-_38331482 Show fit	0.91	ENSMUST00000031850.10 ENSMUST00000114898.3	Zc3hav1 Ensembl NCBI MGI UniProt Show fit	zinc finger CCCH type, antiviral 1
chr4_+_19280850 Show fit	0.91	ENSMUST00000102999.2	Cngb3 Ensembl NCBI MGI UniProt Show fit	cyclic nucleotide gated channel beta 3
chr10_-_129738595 Show fit	0.91	ENSMUST00000071557.2	Olfr815 Ensembl NCBI MGI UniProt Show fit	olfactory receptor 815
chr3_-_106697459 Show fit	0.91	ENSMUST00000038845.10	Cd53 Ensembl NCBI MGI UniProt Show fit	CD53 antigen
chr3_-_10273628 Show fit	0.90	ENSMUST00000029041.6	Fabp4 Ensembl NCBI MGI UniProt Show fit	fatty acid binding protein 4, adipocyte
chr7_+_89814713 Show fit	0.90	ENSMUST00000207084.2	Picalm Ensembl NCBI MGI UniProt Show fit	phosphatidylinositol binding clathrin assembly protein
chr14_-_51295099 Show fit	0.89	ENSMUST00000227764.2	Rnase12 Ensembl NCBI MGI UniProt Show fit	ribonuclease, RNase A family, 12 (non-active)
chrX_+_41241049 Show fit	0.89	ENSMUST00000128799.3	Stag2 Ensembl NCBI MGI UniProt Show fit	stromal antigen 2
chr2_-_111880531 Show fit	0.88	ENSMUST00000213582.2 ENSMUST00000213961.3 ENSMUST00000215531.2	Olfr1312 Ensembl NCBI MGI UniProt Show fit	olfactory receptor 1312
chr11_-_73382303 Show fit	0.88	ENSMUST00000119863.2 ENSMUST00000215358.2 ENSMUST00000214623.2	Olfr381 Ensembl NCBI MGI UniProt Show fit	olfactory receptor 381
chr10_+_12936248 Show fit	0.87	ENSMUST00000193426.6	Plagl1 Ensembl NCBI MGI UniProt Show fit	pleiomorphic adenoma gene-like 1
chr5_-_138169476 Show fit	0.86	ENSMUST00000147920.2	Mcm7 Ensembl NCBI MGI UniProt Show fit	minichromosome maintenance complex component 7
chr11_-_99134885 Show fit	0.86	ENSMUST00000103132.10 ENSMUST00000038214.7	Krt222 Ensembl NCBI MGI UniProt Show fit	keratin 222
chr13_-_103901010 Show fit	0.85	ENSMUST00000210489.2	Srek1 Ensembl NCBI MGI UniProt Show fit	splicing regulatory glutamine/lysine-rich protein 1
chr4_+_109137561 Show fit	0.84	ENSMUST00000177089.8 ENSMUST00000175776.8 ENSMUST00000132165.9	Eps15 Ensembl NCBI MGI UniProt Show fit	epidermal growth factor receptor pathway substrate 15
chr8_+_117670126 Show fit	0.84	ENSMUST00000109099.4	Atmin Ensembl NCBI MGI UniProt Show fit	ATM interactor
chr7_-_103094646 Show fit	0.84	ENSMUST00000215417.2	Olfr605 Ensembl NCBI MGI UniProt Show fit	olfactory receptor 605
chr4_+_59035088 Show fit	0.83	ENSMUST00000041160.13	Gng10 Ensembl NCBI MGI UniProt Show fit	guanine nucleotide binding protein (G protein), gamma 10
chr17_+_34811217 Show fit	0.83	ENSMUST00000038149.13	Pbx2 Ensembl NCBI MGI UniProt Show fit	pre B cell leukemia homeobox 2
chr6_-_122317484 Show fit	0.82	ENSMUST00000112600.9	Phc1 Ensembl NCBI MGI UniProt Show fit	polyhomeotic 1
chr3_+_103739877 Show fit	0.82	ENSMUST00000062945.12	Bcl2l15 Ensembl NCBI MGI UniProt Show fit	BCLl2-like 15
chr7_+_126184108 Show fit	0.82	ENSMUST00000039522.8	Apobr Ensembl NCBI MGI UniProt Show fit	apolipoprotein B receptor
chr12_+_117807607 Show fit	0.82	ENSMUST00000176735.8 ENSMUST00000177339.2	Cdca7l Ensembl NCBI MGI UniProt Show fit	cell division cycle associated 7 like
chr6_-_87510200 Show fit	0.81	ENSMUST00000113637.9 ENSMUST00000071024.7	Arhgap25 Ensembl NCBI MGI UniProt Show fit	Rho GTPase activating protein 25
chr16_-_58344548 Show fit	0.80	ENSMUST00000114357.10	St3gal6 Ensembl NCBI MGI UniProt Show fit	ST3 beta-galactoside alpha-2,3-sialyltransferase 6
chr10_-_128361731 Show fit	0.79	ENSMUST00000026427.8	Esyt1 Ensembl NCBI MGI UniProt Show fit	extended synaptotagmin-like protein 1
chr19_-_6178171 Show fit	0.79	ENSMUST00000154601.8 ENSMUST00000138931.3	Snx15 Ensembl NCBI MGI UniProt Show fit	sorting nexin 15
chr6_-_129449739 Show fit	0.79	ENSMUST00000112076.9 ENSMUST00000184581.3	Clec7a Ensembl NCBI MGI UniProt Show fit	C-type lectin domain family 7, member a
chr17_-_48145466 Show fit	0.79	ENSMUST00000066368.13	Mdfi Ensembl NCBI MGI UniProt Show fit	MyoD family inhibitor
chr1_+_45834645 Show fit	0.79	ENSMUST00000147308.2	Wdr75 Ensembl NCBI MGI UniProt Show fit	WD repeat domain 75
chr8_-_107792264 Show fit	0.78	ENSMUST00000034393.7	Tmed6 Ensembl NCBI MGI UniProt Show fit	transmembrane p24 trafficking protein 6
chr17_-_31348576 Show fit	0.78	ENSMUST00000024827.5	Tff3 Ensembl NCBI MGI UniProt Show fit	trefoil factor 3, intestinal
chr10_-_37014859 Show fit	0.78	ENSMUST00000092584.6	Marcks Ensembl NCBI MGI UniProt Show fit	myristoylated alanine rich protein kinase C substrate
chr13_+_75855695 Show fit	0.78	ENSMUST00000222194.2 ENSMUST00000223535.2 ENSMUST00000222853.2	Ell2 Ensembl NCBI MGI UniProt Show fit	elongation factor for RNA polymerase II 2
chr7_+_30193047 Show fit	0.78	ENSMUST00000058280.13 ENSMUST00000133318.8 ENSMUST00000142575.8 ENSMUST00000131040.2	Prodh2 Ensembl NCBI MGI UniProt Show fit	proline dehydrogenase (oxidase) 2
chr7_-_103778992 Show fit	0.78	ENSMUST00000053743.6	Ubqln5 Ensembl NCBI MGI UniProt Show fit	ubiquilin 5
chr4_-_109522502 Show fit	0.77	ENSMUST00000063531.5	Cdkn2c Ensembl NCBI MGI UniProt Show fit	cyclin dependent kinase inhibitor 2C
chrX_+_152506577 Show fit	0.77	ENSMUST00000140575.8 ENSMUST00000208373.2 ENSMUST00000185492.7 ENSMUST00000149514.8	Nbdy Ensembl NCBI MGI UniProt Show fit	negative regulator of P-body association
chr11_+_50267808 Show fit	0.77	ENSMUST00000109142.8	Hnrnph1 Ensembl NCBI MGI UniProt Show fit	heterogeneous nuclear ribonucleoprotein H1

Network of associatons between targets according to the STRING database.

First level regulatory network of Nkx6-1_Evx1_Hesx1

View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.1	4.3	GO:1904209	regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904207) positive regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904209)
1.1	3.2	GO:0001869	regulation of complement activation, lectin pathway(GO:0001868) negative regulation of complement activation, lectin pathway(GO:0001869)
1.0	2.9	GO:0045660	positive regulation of neutrophil differentiation(GO:0045660)
1.0	2.9	GO:0043973	histone H3-K4 acetylation(GO:0043973)
0.9	2.8	GO:0034378	chylomicron assembly(GO:0034378)
0.8	2.4	GO:1904956	regulation of midbrain dopaminergic neuron differentiation(GO:1904956) regulation of planar cell polarity pathway involved in axis elongation(GO:2000040) negative regulation of planar cell polarity pathway involved in axis elongation(GO:2000041)
0.8	3.1	GO:1901421	positive regulation of response to alcohol(GO:1901421)
0.7	2.1	GO:0070194	synaptonemal complex disassembly(GO:0070194)
0.7	2.1	GO:0060217	hemangioblast cell differentiation(GO:0060217)
0.7	3.4	GO:0038032	termination of G-protein coupled receptor signaling pathway(GO:0038032)
0.6	1.8	GO:0044878	mitotic cytokinesis checkpoint(GO:0044878)
0.6	1.8	GO:0061357	positive regulation of Wnt protein secretion(GO:0061357)
0.6	2.4	GO:0072488	ammonium transmembrane transport(GO:0072488)
0.6	2.3	GO:0048022	negative regulation of melanin biosynthetic process(GO:0048022) negative regulation of secondary metabolite biosynthetic process(GO:1900377)
0.5	3.1	GO:0015692	vanadium ion transport(GO:0015676) lead ion transport(GO:0015692)
0.5	2.1	GO:0090063	positive regulation of microtubule nucleation(GO:0090063)
0.5	2.0	GO:0035633	maintenance of blood-brain barrier(GO:0035633)
0.5	2.0	GO:1901301	regulation of cargo loading into COPII-coated vesicle(GO:1901301)
0.5	1.8	GO:0090309	C-5 methylation of cytosine(GO:0090116) positive regulation of methylation-dependent chromatin silencing(GO:0090309)
0.4	2.2	GO:0070966	nuclear-transcribed mRNA catabolic process, no-go decay(GO:0070966)
0.4	1.3	GO:0035638	patched ligand maturation(GO:0007225) signal maturation(GO:0035638)
0.4	2.4	GO:1900041	negative regulation of interleukin-2 secretion(GO:1900041)
0.4	2.8	GO:0051697	protein delipidation(GO:0051697)
0.4	2.3	GO:0060160	negative regulation of dopamine receptor signaling pathway(GO:0060160)
0.4	3.0	GO:0031179	peptide modification(GO:0031179) leukotriene D4 metabolic process(GO:1901748) leukotriene D4 biosynthetic process(GO:1901750)
0.3	2.4	GO:1904749	regulation of protein localization to nucleolus(GO:1904749)
0.3	1.0	GO:0046985	positive regulation of hemoglobin biosynthetic process(GO:0046985)
0.3	3.6	GO:0030916	otic vesicle formation(GO:0030916)
0.3	1.3	GO:1903225	negative regulation of endodermal cell differentiation(GO:1903225)
0.3	0.9	GO:0002940	tRNA N2-guanine methylation(GO:0002940)
0.3	3.1	GO:1903690	negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
0.3	1.2	GO:0045575	basophil activation(GO:0045575)
0.3	0.3	GO:0000349	generation of catalytic spliceosome for first transesterification step(GO:0000349)
0.3	0.9	GO:0051892	negative regulation of cardioblast differentiation(GO:0051892)
0.3	0.8	GO:0050925	negative regulation of negative chemotaxis(GO:0050925)
0.3	1.6	GO:0061743	motor learning(GO:0061743)
0.3	1.0	GO:2000471	regulation of hematopoietic stem cell migration(GO:2000471) positive regulation of hematopoietic stem cell migration(GO:2000473)
0.3	0.8	GO:0010133	proline catabolic process to glutamate(GO:0010133)
0.3	1.3	GO:1903238	positive regulation of leukocyte tethering or rolling(GO:1903238)
0.3	4.1	GO:0019985	translesion synthesis(GO:0019985)
0.3	1.8	GO:0042541	hemoglobin biosynthetic process(GO:0042541)
0.3	0.8	GO:0002545	chronic inflammatory response to non-antigenic stimulus(GO:0002545) regulation of chronic inflammatory response to non-antigenic stimulus(GO:0002880)
0.3	0.8	GO:0044029	DNA hypomethylation(GO:0044028) hypomethylation of CpG island(GO:0044029)
0.3	3.1	GO:0006268	DNA unwinding involved in DNA replication(GO:0006268)
0.3	1.0	GO:0006649	phospholipid transfer to membrane(GO:0006649)
0.2	1.5	GO:0035694	mitochondrial protein catabolic process(GO:0035694)
0.2	1.2	GO:1903336	negative regulation of vacuolar transport(GO:1903336)
0.2	0.7	GO:0015825	L-serine transport(GO:0015825)
0.2	1.4	GO:1902261	positive regulation of delayed rectifier potassium channel activity(GO:1902261)
0.2	0.2	GO:1904742	regulation of telomeric DNA binding(GO:1904742)
0.2	0.7	GO:1990428	miRNA transport(GO:1990428)
0.2	0.9	GO:0035524	proline transmembrane transport(GO:0035524)
0.2	0.6	GO:0052203	modulation by symbiont of host molecular function(GO:0052055) modulation of catalytic activity in other organism involved in symbiotic interaction(GO:0052203) modulation by host of symbiont catalytic activity(GO:0052422)
0.2	1.3	GO:0007412	axon target recognition(GO:0007412)
0.2	1.4	GO:0016198	axon choice point recognition(GO:0016198)
0.2	1.2	GO:2000774	positive regulation of cellular senescence(GO:2000774)
0.2	2.8	GO:0046884	follicle-stimulating hormone secretion(GO:0046884)
0.2	2.1	GO:2000346	negative regulation of hepatocyte proliferation(GO:2000346)
0.2	0.8	GO:0003017	lymph circulation(GO:0003017)
0.2	1.1	GO:0051661	maintenance of centrosome location(GO:0051661)
0.2	1.3	GO:0006177	GMP biosynthetic process(GO:0006177)
0.2	3.9	GO:0046085	adenosine metabolic process(GO:0046085)
0.2	2.4	GO:1904776	regulation of protein localization to cell cortex(GO:1904776) positive regulation of protein localization to cell cortex(GO:1904778)
0.2	1.3	GO:0021767	mammillary body development(GO:0021767) mammillary axonal complex development(GO:0061373) positive regulation of lens fiber cell differentiation(GO:1902748)
0.2	0.7	GO:1990091	sodium-dependent self proteolysis(GO:1990091)
0.2	0.7	GO:0009744	response to sucrose(GO:0009744) response to disaccharide(GO:0034285)
0.2	1.8	GO:0032261	purine nucleotide salvage(GO:0032261) IMP salvage(GO:0032264)
0.2	2.6	GO:0071688	striated muscle myosin thick filament assembly(GO:0071688)
0.2	1.7	GO:2000741	positive regulation of mesenchymal stem cell differentiation(GO:2000741)
0.2	0.2	GO:0003162	atrioventricular node development(GO:0003162)
0.2	2.4	GO:1900028	negative regulation of ruffle assembly(GO:1900028)
0.2	3.4	GO:0030953	astral microtubule organization(GO:0030953)
0.2	1.8	GO:0035873	lactate transport(GO:0015727) lactate transmembrane transport(GO:0035873) plasma membrane lactate transport(GO:0035879)
0.2	0.6	GO:0046098	guanine metabolic process(GO:0046098)
0.2	0.3	GO:0061346	non-canonical Wnt signaling pathway involved in heart development(GO:0061341) planar cell polarity pathway involved in heart morphogenesis(GO:0061346)
0.1	0.9	GO:1902963	regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902962) negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902963)
0.1	0.3	GO:0043060	meiotic metaphase I plate congression(GO:0043060) meiotic metaphase plate congression(GO:0051311)
0.1	0.4	GO:0060166	olfactory pit development(GO:0060166)
0.1	0.7	GO:0055005	ventricular cardiac myofibril assembly(GO:0055005)
0.1	1.0	GO:2001205	negative regulation of osteoclast development(GO:2001205)
0.1	1.4	GO:0006686	sphingomyelin biosynthetic process(GO:0006686)
0.1	0.7	GO:0097309	cap1 mRNA methylation(GO:0097309)
0.1	0.5	GO:0016332	establishment or maintenance of polarity of embryonic epithelium(GO:0016332)
0.1	1.6	GO:0035520	monoubiquitinated protein deubiquitination(GO:0035520)
0.1	0.9	GO:0031848	protection from non-homologous end joining at telomere(GO:0031848)
0.1	1.1	GO:0090656	positive regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090267) t-circle formation(GO:0090656)
0.1	0.4	GO:0048478	replication fork protection(GO:0048478)
0.1	1.3	GO:0019065	receptor-mediated endocytosis of virus by host cell(GO:0019065) endocytosis involved in viral entry into host cell(GO:0075509)
0.1	1.0	GO:0090520	sphingolipid mediated signaling pathway(GO:0090520)
0.1	1.3	GO:2000766	negative regulation of cytoplasmic translation(GO:2000766)
0.1	0.5	GO:0072362	regulation of glycolytic process by negative regulation of transcription from RNA polymerase II promoter(GO:0072362)
0.1	1.8	GO:0090231	regulation of spindle checkpoint(GO:0090231)
0.1	0.2	GO:0021502	neural fold elevation formation(GO:0021502)
0.1	0.5	GO:2001280	positive regulation of prostaglandin biosynthetic process(GO:0031394) positive regulation of unsaturated fatty acid biosynthetic process(GO:2001280)
0.1	0.3	GO:2000158	positive regulation of ubiquitin-specific protease activity(GO:2000158)
0.1	0.1	GO:0002729	positive regulation of natural killer cell cytokine production(GO:0002729)
0.1	0.7	GO:1900170	negative regulation of glucocorticoid mediated signaling pathway(GO:1900170)
0.1	2.6	GO:0001833	inner cell mass cell proliferation(GO:0001833)
0.1	2.2	GO:0001675	acrosome assembly(GO:0001675)
0.1	2.8	GO:0007095	mitotic G2 DNA damage checkpoint(GO:0007095)
0.1	0.9	GO:0032876	negative regulation of DNA endoreduplication(GO:0032876)
0.1	0.7	GO:1903232	platelet dense granule organization(GO:0060155) phagosome acidification(GO:0090383) melanosome assembly(GO:1903232)
0.1	0.3	GO:0032685	negative regulation of granulocyte macrophage colony-stimulating factor production(GO:0032685)
0.1	0.6	GO:0035553	oxidative single-stranded RNA demethylation(GO:0035553)
0.1	1.9	GO:2000096	positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096)
0.1	0.9	GO:0031937	positive regulation of chromatin silencing(GO:0031937)
0.1	0.7	GO:2000323	negative regulation of glucocorticoid receptor signaling pathway(GO:2000323)
0.1	0.7	GO:0097461	ferric iron import into cell(GO:0097461) ferric iron import across plasma membrane(GO:0098706)
0.1	1.2	GO:0016056	rhodopsin mediated signaling pathway(GO:0016056)
0.1	0.3	GO:2000118	regulation of sodium-dependent phosphate transport(GO:2000118)
0.1	0.2	GO:0071596	ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596)
0.1	0.8	GO:0090070	positive regulation of ribosome biogenesis(GO:0090070) positive regulation of rRNA processing(GO:2000234)
0.1	0.8	GO:0042795	snRNA transcription from RNA polymerase II promoter(GO:0042795)
0.1	0.8	GO:0048023	positive regulation of melanin biosynthetic process(GO:0048023) positive regulation of secondary metabolite biosynthetic process(GO:1900378)
0.1	0.3	GO:0097277	creatinine homeostasis(GO:0097273) cellular ammonia homeostasis(GO:0097275) cellular creatinine homeostasis(GO:0097276) cellular urea homeostasis(GO:0097277)
0.1	0.3	GO:1905053	regulation of base-excision repair(GO:1905051) positive regulation of base-excision repair(GO:1905053)
0.1	2.9	GO:0031146	SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
0.1	0.2	GO:1903045	neural crest cell migration involved in sympathetic nervous system development(GO:1903045)
0.1	1.4	GO:0033234	negative regulation of protein sumoylation(GO:0033234)
0.1	2.7	GO:0006779	porphyrin-containing compound biosynthetic process(GO:0006779)
0.1	2.0	GO:0045898	regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045898)
0.1	0.3	GO:1905077	negative regulation of interleukin-17 secretion(GO:1905077)
0.1	0.4	GO:0099527	postsynapse to nucleus signaling pathway(GO:0099527)
0.1	7.5	GO:0051225	spindle assembly(GO:0051225)
0.1	0.2	GO:0000451	rRNA 2'-O-methylation(GO:0000451)
0.1	0.2	GO:1901994	negative regulation of meiotic cell cycle phase transition(GO:1901994)
0.1	0.6	GO:0061304	retinal blood vessel morphogenesis(GO:0061304)
0.1	0.3	GO:0007113	endomitotic cell cycle(GO:0007113)
0.1	0.9	GO:0071360	cellular response to exogenous dsRNA(GO:0071360)
0.1	0.2	GO:0070904	L-ascorbic acid transport(GO:0015882) transepithelial L-ascorbic acid transport(GO:0070904)
0.1	0.9	GO:0030277	maintenance of gastrointestinal epithelium(GO:0030277)
0.1	2.6	GO:0000387	spliceosomal snRNP assembly(GO:0000387)
0.1	1.6	GO:0050911	detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.1	1.0	GO:0006337	nucleosome disassembly(GO:0006337)
0.1	0.3	GO:1903224	regulation of endodermal cell differentiation(GO:1903224)
0.1	1.1	GO:1902083	negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.1	0.4	GO:0003219	cardiac right ventricle formation(GO:0003219)
0.1	0.5	GO:0033353	S-adenosylmethionine cycle(GO:0033353)
0.1	1.2	GO:0002726	positive regulation of T cell cytokine production(GO:0002726)
0.1	0.5	GO:0045835	negative regulation of meiotic nuclear division(GO:0045835)
0.1	1.1	GO:2000480	negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.1	0.5	GO:0090527	actin filament reorganization(GO:0090527)
0.1	0.7	GO:0031936	negative regulation of chromatin silencing(GO:0031936)
0.1	0.2	GO:0097156	fasciculation of motor neuron axon(GO:0097156)
0.0	2.2	GO:0090162	establishment of epithelial cell polarity(GO:0090162)
0.0	0.2	GO:1902966	regulation of protein localization to early endosome(GO:1902965) positive regulation of protein localization to early endosome(GO:1902966)
0.0	0.1	GO:1904139	microglial cell migration(GO:1904124) regulation of microglial cell migration(GO:1904139)
0.0	0.9	GO:1902857	positive regulation of nonmotile primary cilium assembly(GO:1902857)
0.0	0.4	GO:0036309	protein localization to M-band(GO:0036309) protein localization to T-tubule(GO:0036371)
0.0	0.9	GO:0071578	zinc II ion transmembrane import(GO:0071578)
0.0	0.4	GO:0071787	endoplasmic reticulum tubular network assembly(GO:0071787)
0.0	0.1	GO:2001200	positive regulation of dendritic cell differentiation(GO:2001200)
0.0	0.6	GO:0000492	box C/D snoRNP assembly(GO:0000492)
0.0	0.5	GO:0032070	regulation of deoxyribonuclease activity(GO:0032070) negative regulation of nuclease activity(GO:0032074)
0.0	0.3	GO:0000821	regulation of arginine metabolic process(GO:0000821)
0.0	0.2	GO:0070858	negative regulation of bile acid biosynthetic process(GO:0070858) negative regulation of bile acid metabolic process(GO:1904252)
0.0	1.4	GO:0050860	negative regulation of T cell receptor signaling pathway(GO:0050860)
0.0	0.3	GO:1903054	negative regulation of extracellular matrix organization(GO:1903054)
0.0	1.2	GO:0007064	mitotic sister chromatid cohesion(GO:0007064)
0.0	0.2	GO:0017183	peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.0	0.3	GO:0045743	positive regulation of fibroblast growth factor receptor signaling pathway(GO:0045743)
0.0	0.6	GO:0070389	chaperone cofactor-dependent protein refolding(GO:0070389)
0.0	0.1	GO:0060686	negative regulation of prostatic bud formation(GO:0060686)
0.0	0.2	GO:0071680	response to indole-3-methanol(GO:0071680) cellular response to indole-3-methanol(GO:0071681) negative regulation of integrin-mediated signaling pathway(GO:2001045)
0.0	0.2	GO:2000354	negative regulation of immature T cell proliferation(GO:0033087) regulation of ovarian follicle development(GO:2000354)
0.0	0.6	GO:0010972	negative regulation of G2/M transition of mitotic cell cycle(GO:0010972)
0.0	0.2	GO:0030309	poly-N-acetyllactosamine metabolic process(GO:0030309) poly-N-acetyllactosamine biosynthetic process(GO:0030311)
0.0	0.4	GO:0003172	primary heart field specification(GO:0003138) sinoatrial valve development(GO:0003172) sinoatrial valve morphogenesis(GO:0003185) positive regulation of macrophage apoptotic process(GO:2000111)
0.0	0.2	GO:0035660	MyD88-dependent toll-like receptor 4 signaling pathway(GO:0035660)
0.0	1.0	GO:0050872	white fat cell differentiation(GO:0050872)
0.0	0.8	GO:0043968	histone H2A acetylation(GO:0043968)
0.0	3.4	GO:0045576	mast cell activation(GO:0045576)
0.0	0.2	GO:0045218	zonula adherens maintenance(GO:0045218)
0.0	0.5	GO:0035970	peptidyl-threonine dephosphorylation(GO:0035970)
0.0	0.3	GO:0097647	calcitonin family receptor signaling pathway(GO:0097646) amylin receptor signaling pathway(GO:0097647)
0.0	0.5	GO:0045974	miRNA mediated inhibition of translation(GO:0035278) negative regulation of translation, ncRNA-mediated(GO:0040033) regulation of translation, ncRNA-mediated(GO:0045974)
0.0	1.4	GO:0006284	base-excision repair(GO:0006284)
0.0	0.4	GO:1904659	glucose transmembrane transport(GO:1904659)
0.0	2.1	GO:0051693	actin filament capping(GO:0051693)
0.0	0.6	GO:0048934	peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.0	0.9	GO:0071108	protein K48-linked deubiquitination(GO:0071108)
0.0	2.9	GO:0000380	alternative mRNA splicing, via spliceosome(GO:0000380)
0.0	0.3	GO:0070914	UV-damage excision repair(GO:0070914)
0.0	0.3	GO:0048251	elastic fiber assembly(GO:0048251)
0.0	0.3	GO:0031119	tRNA pseudouridine synthesis(GO:0031119)
0.0	0.6	GO:0051764	actin crosslink formation(GO:0051764)
0.0	0.1	GO:1903487	regulation of lactation(GO:1903487)
0.0	0.3	GO:1901621	negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:1901621)
0.0	0.2	GO:2000790	regulation of mesenchymal cell proliferation involved in lung development(GO:2000790) negative regulation of mesenchymal cell proliferation involved in lung development(GO:2000791)
0.0	0.2	GO:0014816	skeletal muscle satellite cell differentiation(GO:0014816)
0.0	0.1	GO:0060005	vestibular reflex(GO:0060005)
0.0	2.1	GO:1901799	negative regulation of proteasomal protein catabolic process(GO:1901799)
0.0	0.5	GO:0006851	mitochondrial calcium ion transport(GO:0006851)
0.0	0.2	GO:0015705	iodide transport(GO:0015705)
0.0	0.7	GO:0006907	pinocytosis(GO:0006907)
0.0	1.6	GO:0018279	protein N-linked glycosylation via asparagine(GO:0018279)
0.0	0.2	GO:0032202	telomere assembly(GO:0032202)
0.0	0.3	GO:2000794	positive regulation of epithelial cell proliferation involved in lung morphogenesis(GO:0060501) regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000794)
0.0	0.6	GO:0043984	histone H4-K16 acetylation(GO:0043984)
0.0	0.4	GO:0097500	receptor localization to nonmotile primary cilium(GO:0097500)
0.0	1.2	GO:0006730	one-carbon metabolic process(GO:0006730)
0.0	0.4	GO:0001778	plasma membrane repair(GO:0001778)
0.0	0.6	GO:0061050	regulation of cell growth involved in cardiac muscle cell development(GO:0061050)
0.0	0.7	GO:0061014	positive regulation of mRNA catabolic process(GO:0061014)
0.0	18.6	GO:0007608	sensory perception of smell(GO:0007608)
0.0	0.1	GO:0042488	positive regulation of odontogenesis of dentin-containing tooth(GO:0042488)
0.0	0.1	GO:0098885	modification of postsynaptic actin cytoskeleton(GO:0098885)
0.0	0.2	GO:0045217	cell-cell junction maintenance(GO:0045217)
0.0	0.2	GO:0032485	regulation of Ral protein signal transduction(GO:0032485)
0.0	1.2	GO:0050873	brown fat cell differentiation(GO:0050873)
0.0	0.3	GO:0010739	positive regulation of protein kinase A signaling(GO:0010739)
0.0	0.4	GO:0086069	bundle of His cell to Purkinje myocyte communication(GO:0086069)
0.0	2.6	GO:0001889	liver development(GO:0001889)
0.0	0.5	GO:0044146	negative regulation of growth of symbiont involved in interaction with host(GO:0044146)
0.0	0.1	GO:0001830	trophectodermal cell fate commitment(GO:0001830)
0.0	0.1	GO:0006421	asparaginyl-tRNA aminoacylation(GO:0006421)
0.0	2.1	GO:0006261	DNA-dependent DNA replication(GO:0006261)
0.0	0.1	GO:0045726	positive regulation of integrin biosynthetic process(GO:0045726)
0.0	0.1	GO:2000617	positive regulation of histone H3-K9 acetylation(GO:2000617)
0.0	0.2	GO:1900113	negative regulation of histone H3-K9 trimethylation(GO:1900113)
0.0	0.1	GO:0075525	viral translational termination-reinitiation(GO:0075525)
0.0	0.3	GO:2001256	regulation of store-operated calcium entry(GO:2001256)
0.0	0.2	GO:0043545	molybdopterin cofactor biosynthetic process(GO:0032324) molybdopterin cofactor metabolic process(GO:0043545) prosthetic group metabolic process(GO:0051189)
0.0	0.4	GO:0034587	piRNA metabolic process(GO:0034587)
0.0	1.7	GO:0002224	toll-like receptor signaling pathway(GO:0002224)
0.0	5.2	GO:0042254	ribosome biogenesis(GO:0042254)
0.0	0.2	GO:0045624	positive regulation of T-helper cell differentiation(GO:0045624)
0.0	0.2	GO:0048280	vesicle fusion with Golgi apparatus(GO:0048280)
0.0	0.3	GO:0009950	dorsal/ventral axis specification(GO:0009950)
0.0	0.4	GO:1904030	negative regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045736) negative regulation of cyclin-dependent protein kinase activity(GO:1904030)
0.0	0.2	GO:1901550	regulation of endothelial cell development(GO:1901550) regulation of establishment of endothelial barrier(GO:1903140)
0.0	0.2	GO:0090196	chemokine secretion(GO:0090195) regulation of chemokine secretion(GO:0090196) positive regulation of chemokine secretion(GO:0090197)
0.0	0.9	GO:0016574	histone ubiquitination(GO:0016574)
0.0	0.3	GO:0000338	protein deneddylation(GO:0000338)
0.0	0.9	GO:0006493	protein O-linked glycosylation(GO:0006493)
0.0	1.1	GO:1900181	negative regulation of protein localization to nucleus(GO:1900181)
0.0	0.3	GO:0034453	microtubule anchoring(GO:0034453)
0.0	2.4	GO:0050853	B cell receptor signaling pathway(GO:0050853)
0.0	0.1	GO:1901409	positive regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901409)
0.0	0.3	GO:0007194	negative regulation of adenylate cyclase activity(GO:0007194)
0.0	0.1	GO:1900004	regulation of serine-type endopeptidase activity(GO:1900003) negative regulation of serine-type endopeptidase activity(GO:1900004) regulation of serine-type peptidase activity(GO:1902571) negative regulation of serine-type peptidase activity(GO:1902572)
0.0	0.2	GO:0072501	cellular divalent inorganic anion homeostasis(GO:0072501)
0.0	0.1	GO:0021814	cell motility involved in cerebral cortex radial glia guided migration(GO:0021814) modulation of microtubule cytoskeleton involved in cerebral cortex radial glia guided migration(GO:0021815)
0.0	0.2	GO:0030322	stabilization of membrane potential(GO:0030322)
0.0	0.1	GO:2000298	regulation of Rho-dependent protein serine/threonine kinase activity(GO:2000298)
0.0	0.1	GO:0007258	JUN phosphorylation(GO:0007258)
0.0	0.2	GO:0050957	equilibrioception(GO:0050957)
0.0	0.8	GO:0005978	glycogen biosynthetic process(GO:0005978) glucan biosynthetic process(GO:0009250)
0.0	0.4	GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:0000184)
0.0	0.2	GO:0032486	Rap protein signal transduction(GO:0032486)
0.0	1.1	GO:0043484	regulation of RNA splicing(GO:0043484)
0.0	0.1	GO:0090126	protein complex assembly involved in synapse maturation(GO:0090126)
0.0	0.1	GO:2000580	regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)
0.0	1.0	GO:1903955	positive regulation of protein targeting to mitochondrion(GO:1903955)
0.0	0.2	GO:0040023	nuclear migration(GO:0007097) establishment of nucleus localization(GO:0040023)
0.0	1.0	GO:0045454	cell redox homeostasis(GO:0045454)
0.0	0.1	GO:0045162	clustering of voltage-gated sodium channels(GO:0045162)
0.0	1.3	GO:0051028	mRNA transport(GO:0051028)
0.0	0.1	GO:1901741	positive regulation of myoblast fusion(GO:1901741)
0.0	0.3	GO:0008045	motor neuron axon guidance(GO:0008045)
0.0	0.1	GO:0018230	peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.0	3.1	GO:1903754	cortical microtubule plus-end(GO:1903754) cytoplasmic microtubule plus-end(GO:1904511)
0.7	2.1	GO:0033193	Lsd1/2 complex(GO:0033193)
0.6	2.2	GO:0008623	CHRAC(GO:0008623)
0.5	2.1	GO:0000942	condensed nuclear chromosome outer kinetochore(GO:0000942)
0.5	5.2	GO:0033093	Weibel-Palade body(GO:0033093)
0.5	3.1	GO:0070826	paraferritin complex(GO:0070826)
0.4	1.3	GO:0005588	collagen type V trimer(GO:0005588)
0.4	2.1	GO:0000444	MIS12/MIND type complex(GO:0000444)
0.3	4.1	GO:0042555	MCM complex(GO:0042555)
0.3	0.8	GO:0005943	phosphatidylinositol 3-kinase complex, class IA(GO:0005943)
0.2	0.8	GO:0042585	germinal vesicle(GO:0042585)
0.2	3.7	GO:0005852	eukaryotic translation initiation factor 3 complex(GO:0005852)
0.2	0.6	GO:0071007	U2-type catalytic step 2 spliceosome(GO:0071007)
0.2	1.4	GO:0033162	melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.2	2.3	GO:0032591	dendritic spine membrane(GO:0032591)
0.2	2.4	GO:0005736	DNA-directed RNA polymerase I complex(GO:0005736)
0.2	1.8	GO:0000815	ESCRT III complex(GO:0000815)
0.1	6.0	GO:0005721	pericentric heterochromatin(GO:0005721)
0.1	2.1	GO:0005869	dynactin complex(GO:0005869)
0.1	0.9	GO:0072487	MSL complex(GO:0072487)
0.1	1.3	GO:0019815	B cell receptor complex(GO:0019815)
0.1	0.9	GO:0070381	endosome to plasma membrane transport vesicle(GO:0070381)
0.1	0.9	GO:0033063	Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
0.1	6.2	GO:0031430	M band(GO:0031430)
0.1	1.8	GO:0032797	SMN complex(GO:0032797)
0.1	0.8	GO:0097443	sorting endosome(GO:0097443)
0.1	0.3	GO:0032545	CURI complex(GO:0032545) UTP-C complex(GO:0034456)
0.1	0.6	GO:0000125	PCAF complex(GO:0000125)
0.1	1.4	GO:0034709	methylosome(GO:0034709)
0.1	1.1	GO:0072687	meiotic spindle(GO:0072687)
0.1	2.6	GO:0008074	guanylate cyclase complex, soluble(GO:0008074)
0.1	0.3	GO:0060187	cell pole(GO:0060187)
0.1	0.3	GO:0005715	chiasma(GO:0005712) late recombination nodule(GO:0005715)
0.1	1.8	GO:0030127	COPII vesicle coat(GO:0030127)
0.1	0.6	GO:0098651	collagen type IV trimer(GO:0005587) network-forming collagen trimer(GO:0098642) collagen network(GO:0098645) basement membrane collagen trimer(GO:0098651)
0.1	1.3	GO:0030122	AP-2 adaptor complex(GO:0030122)
0.1	1.2	GO:0000138	Golgi trans cisterna(GO:0000138)
0.1	0.5	GO:0032777	Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.1	0.9	GO:0001739	sex chromatin(GO:0001739)
0.1	0.7	GO:0045252	oxoglutarate dehydrogenase complex(GO:0045252)
0.1	0.1	GO:0002944	cyclin K-CDK12 complex(GO:0002944) cyclin K-CDK13 complex(GO:0002945)
0.1	2.4	GO:0030904	retromer complex(GO:0030904)
0.1	2.2	GO:0031672	A band(GO:0031672)
0.1	0.8	GO:0000974	Prp19 complex(GO:0000974)
0.1	4.8	GO:0022625	cytosolic large ribosomal subunit(GO:0022625)
0.1	3.1	GO:0097440	apical dendrite(GO:0097440)
0.1	0.4	GO:0071547	piP-body(GO:0071547)
0.1	0.7	GO:0071598	neuronal ribonucleoprotein granule(GO:0071598)
0.1	1.3	GO:1990124	messenger ribonucleoprotein complex(GO:1990124)
0.1	0.3	GO:0044307	dendritic branch(GO:0044307)
0.1	2.2	GO:0035371	microtubule plus-end(GO:0035371)
0.1	0.9	GO:0033276	transcription factor TFTC complex(GO:0033276)
0.1	1.1	GO:0031527	filopodium membrane(GO:0031527)
0.1	3.3	GO:0008023	transcription elongation factor complex(GO:0008023)
0.0	0.7	GO:0000177	cytoplasmic exosome (RNase complex)(GO:0000177)
0.0	0.5	GO:0016272	prefoldin complex(GO:0016272)
0.0	0.2	GO:0071953	elastic fiber(GO:0071953)
0.0	0.6	GO:0034464	BBSome(GO:0034464)
0.0	1.8	GO:0032839	dendrite cytoplasm(GO:0032839)
0.0	0.8	GO:0031258	lamellipodium membrane(GO:0031258)
0.0	0.5	GO:0035068	micro-ribonucleoprotein complex(GO:0035068)
0.0	0.3	GO:0072357	PTW/PP1 phosphatase complex(GO:0072357)
0.0	0.3	GO:0005952	cAMP-dependent protein kinase complex(GO:0005952)
0.0	1.6	GO:0035145	exon-exon junction complex(GO:0035145)
0.0	1.3	GO:0031588	nucleotide-activated protein kinase complex(GO:0031588)
0.0	0.4	GO:0070652	HAUS complex(GO:0070652)
0.0	0.7	GO:0036038	MKS complex(GO:0036038)
0.0	1.2	GO:0043034	costamere(GO:0043034)
0.0	0.5	GO:0005688	U6 snRNP(GO:0005688)
0.0	1.1	GO:0005680	anaphase-promoting complex(GO:0005680)
0.0	0.3	GO:0031465	Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.0	4.1	GO:0031594	neuromuscular junction(GO:0031594)
0.0	6.0	GO:0030863	cortical cytoskeleton(GO:0030863)
0.0	3.1	GO:0019005	SCF ubiquitin ligase complex(GO:0019005)
0.0	0.2	GO:0012507	ER to Golgi transport vesicle membrane(GO:0012507)
0.0	0.2	GO:0000308	cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308)
0.0	1.5	GO:0001772	immunological synapse(GO:0001772)
0.0	0.5	GO:0005915	zonula adherens(GO:0005915)
0.0	0.6	GO:0030056	hemidesmosome(GO:0030056)
0.0	0.3	GO:0031211	serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.0	0.2	GO:0098554	cytoplasmic side of endoplasmic reticulum membrane(GO:0098554)
0.0	0.1	GO:0097454	Schwann cell microvillus(GO:0097454)
0.0	1.0	GO:0008305	integrin complex(GO:0008305)
0.0	0.3	GO:0008250	oligosaccharyltransferase complex(GO:0008250)
0.0	0.1	GO:0048269	methionine adenosyltransferase complex(GO:0048269)
0.0	0.1	GO:0071438	invadopodium membrane(GO:0071438)
0.0	2.1	GO:0001750	photoreceptor outer segment(GO:0001750)
0.0	0.2	GO:0000137	Golgi cis cisterna(GO:0000137)
0.0	0.5	GO:0016580	Sin3 complex(GO:0016580)
0.0	0.3	GO:0031080	nuclear pore outer ring(GO:0031080)
0.0	2.6	GO:0000792	heterochromatin(GO:0000792)
0.0	0.9	GO:0030673	axolemma(GO:0030673)
0.0	0.2	GO:0002193	MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.0	0.1	GO:0044327	dendritic spine head(GO:0044327)
0.0	0.1	GO:0034274	Atg12-Atg5-Atg16 complex(GO:0034274)
0.0	0.3	GO:0030061	mitochondrial crista(GO:0030061)
0.0	2.0	GO:0016363	nuclear matrix(GO:0016363)
0.0	3.2	GO:0000775	chromosome, centromeric region(GO:0000775)
0.0	3.6	GO:0090575	RNA polymerase II transcription factor complex(GO:0090575)
0.0	1.3	GO:0005834	heterotrimeric G-protein complex(GO:0005834)
0.0	0.5	GO:0046930	pore complex(GO:0046930)
0.0	0.3	GO:0043189	NuA4 histone acetyltransferase complex(GO:0035267) H4/H2A histone acetyltransferase complex(GO:0043189) H4 histone acetyltransferase complex(GO:1902562)
0.0	0.8	GO:0032809	neuronal cell body membrane(GO:0032809)
0.0	0.1	GO:1990696	stereocilia ankle link complex(GO:0002142) USH2 complex(GO:1990696)
0.0	0.5	GO:0071565	nBAF complex(GO:0071565)
0.0	0.6	GO:0030140	trans-Golgi network transport vesicle(GO:0030140)
0.0	3.3	GO:0005681	spliceosomal complex(GO:0005681)
0.0	1.5	GO:0005643	nuclear pore(GO:0005643)
0.0	0.2	GO:0031315	extrinsic component of mitochondrial outer membrane(GO:0031315)
0.0	0.6	GO:0015030	Cajal body(GO:0015030)
0.0	0.7	GO:0005921	gap junction(GO:0005921)
0.0	1.5	GO:0000784	nuclear chromosome, telomeric region(GO:0000784)
0.0	1.1	GO:0016328	lateral plasma membrane(GO:0016328)
0.0	0.5	GO:0042588	zymogen granule(GO:0042588)
0.0	0.2	GO:0000276	mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0	0.4	GO:0071782	endoplasmic reticulum tubular network(GO:0071782)
0.0	0.2	GO:0035253	ciliary rootlet(GO:0035253)
0.0	0.2	GO:0005671	Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.0	2.1	GO:0001650	fibrillar center(GO:0001650)
0.0	0.0	GO:0014701	junctional sarcoplasmic reticulum membrane(GO:0014701)
0.0	2.2	GO:0030027	lamellipodium(GO:0030027)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.1	3.2	GO:0019959	interleukin-8 binding(GO:0019959)
0.6	1.8	GO:0003870	5-aminolevulinate synthase activity(GO:0003870) N-succinyltransferase activity(GO:0016749)
0.5	3.1	GO:0015094	cadmium ion transmembrane transporter activity(GO:0015086) lead ion transmembrane transporter activity(GO:0015094) vanadium ion transmembrane transporter activity(GO:0015100) ferrous iron uptake transmembrane transporter activity(GO:0015639)
0.4	2.2	GO:0008273	calcium, potassium:sodium antiporter activity(GO:0008273)
0.4	2.1	GO:0010997	anaphase-promoting complex binding(GO:0010997)
0.4	1.4	GO:0008311	double-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008311)
0.3	1.0	GO:0090555	phosphatidylethanolamine-translocating ATPase activity(GO:0090555)
0.3	2.3	GO:0031750	D3 dopamine receptor binding(GO:0031750)
0.3	2.7	GO:0008093	cytoskeletal adaptor activity(GO:0008093)
0.3	2.4	GO:0005094	Rho GDP-dissociation inhibitor activity(GO:0005094)
0.3	0.8	GO:0004373	glycogen (starch) synthase activity(GO:0004373)
0.3	3.0	GO:0036374	glutathione hydrolase activity(GO:0036374)
0.2	1.0	GO:0030519	snoRNP binding(GO:0030519)
0.2	1.0	GO:0031694	alpha-2A adrenergic receptor binding(GO:0031694)
0.2	0.7	GO:0004948	calcitonin receptor activity(GO:0004948)
0.2	0.7	GO:0036461	BLOC-2 complex binding(GO:0036461)
0.2	1.3	GO:0003938	IMP dehydrogenase activity(GO:0003938)
0.2	2.2	GO:0004064	arylesterase activity(GO:0004064)
0.2	1.5	GO:0052798	beta-galactoside alpha-2,3-sialyltransferase activity(GO:0052798)
0.2	1.2	GO:0047493	sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.2	0.9	GO:0004809	tRNA (guanine-N2-)-methyltransferase activity(GO:0004809)
0.2	1.7	GO:0019960	C-X3-C chemokine binding(GO:0019960)
0.2	2.4	GO:0001054	RNA polymerase I activity(GO:0001054)
0.2	1.8	GO:0003876	AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.2	4.1	GO:0019865	immunoglobulin binding(GO:0019865)
0.2	3.9	GO:0008253	5'-nucleotidase activity(GO:0008253)
0.2	1.6	GO:0015193	L-proline transmembrane transporter activity(GO:0015193)
0.2	1.8	GO:0003886	DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.2	0.9	GO:0005223	intracellular cGMP activated cation channel activity(GO:0005223)
0.2	0.6	GO:0004574	oligo-1,6-glucosidase activity(GO:0004574)
0.1	0.6	GO:0004741	[pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
0.1	1.2	GO:0001594	trace-amine receptor activity(GO:0001594)
0.1	2.2	GO:0030274	LIM domain binding(GO:0030274)
0.1	2.4	GO:0005522	profilin binding(GO:0005522)
0.1	3.1	GO:0002162	dystroglycan binding(GO:0002162)
0.1	3.1	GO:0022840	leak channel activity(GO:0022840) narrow pore channel activity(GO:0022842)
0.1	0.1	GO:0070915	lysophosphatidic acid receptor activity(GO:0070915)
0.1	1.1	GO:0035727	lysophosphatidic acid binding(GO:0035727)
0.1	1.1	GO:0008821	crossover junction endodeoxyribonuclease activity(GO:0008821)
0.1	1.5	GO:0004908	interleukin-1 receptor activity(GO:0004908)
0.1	2.6	GO:0010314	phosphatidylinositol-5-phosphate binding(GO:0010314)
0.1	0.8	GO:0016716	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, another compound as one donor, and incorporation of one atom of oxygen(GO:0016716)
0.1	2.6	GO:0097493	structural molecule activity conferring elasticity(GO:0097493)
0.1	0.5	GO:0004711	ribosomal protein S6 kinase activity(GO:0004711)
0.1	0.6	GO:0034648	histone demethylase activity (H3-dimethyl-K4 specific)(GO:0034648)
0.1	2.4	GO:0015643	toxic substance binding(GO:0015643)
0.1	0.5	GO:0004346	glucose-6-phosphatase activity(GO:0004346) sugar-terminal-phosphatase activity(GO:0050309)
0.1	1.8	GO:0031852	mu-type opioid receptor binding(GO:0031852)
0.1	0.7	GO:0038049	glucocorticoid receptor activity(GO:0004883) transcription factor activity, ligand-activated RNA polymerase II transcription factor binding(GO:0038049) glucocorticoid-activated RNA polymerase II transcription factor binding transcription factor activity(GO:0038051)
0.1	0.7	GO:0004483	mRNA (nucleoside-2'-O-)-methyltransferase activity(GO:0004483)
0.1	0.9	GO:0035312	5'-3' exodeoxyribonuclease activity(GO:0035312)
0.1	0.3	GO:0035800	deubiquitinase activator activity(GO:0035800)
0.1	0.7	GO:0004591	oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
0.1	1.3	GO:0008526	phosphatidylinositol transporter activity(GO:0008526)
0.1	0.4	GO:0031013	troponin I binding(GO:0031013)
0.1	0.3	GO:0005169	neurotrophin TRKB receptor binding(GO:0005169)
0.1	0.6	GO:0035515	oxidative RNA demethylase activity(GO:0035515)
0.1	2.1	GO:0070628	proteasome binding(GO:0070628)
0.1	4.1	GO:0004003	ATP-dependent DNA helicase activity(GO:0004003)
0.1	0.4	GO:0015440	peptide-transporting ATPase activity(GO:0015440)
0.1	0.7	GO:0008823	cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
0.1	1.1	GO:0004128	cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128)
0.1	0.8	GO:0008046	axon guidance receptor activity(GO:0008046)
0.1	0.7	GO:0001849	complement component C1q binding(GO:0001849)
0.1	2.0	GO:0042813	Wnt-activated receptor activity(GO:0042813)
0.1	2.9	GO:0008187	poly-pyrimidine tract binding(GO:0008187)
0.1	2.7	GO:0004709	MAP kinase kinase kinase activity(GO:0004709)
0.1	0.3	GO:0071209	histone pre-mRNA DCP binding(GO:0071208) U7 snRNA binding(GO:0071209)
0.1	1.0	GO:0005049	nuclear export signal receptor activity(GO:0005049)
0.1	2.9	GO:0070840	dynein complex binding(GO:0070840)
0.1	0.7	GO:1990247	N6-methyladenosine-containing RNA binding(GO:1990247)
0.1	0.3	GO:0032137	guanine/thymine mispair binding(GO:0032137)
0.1	1.3	GO:0016208	AMP binding(GO:0016208)
0.1	0.5	GO:0004013	adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.1	3.4	GO:0001965	G-protein alpha-subunit binding(GO:0001965)
0.1	0.4	GO:0004977	melanocortin receptor activity(GO:0004977)
0.1	0.6	GO:0001075	transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075)
0.1	1.2	GO:0043522	leucine zipper domain binding(GO:0043522)
0.1	0.2	GO:0070039	rRNA (guanosine-2'-O-)-methyltransferase activity(GO:0070039)
0.1	0.9	GO:0017162	aryl hydrocarbon receptor binding(GO:0017162)
0.1	0.9	GO:0017151	DEAD/H-box RNA helicase binding(GO:0017151)
0.1	0.2	GO:0008520	L-ascorbate:sodium symporter activity(GO:0008520) L-ascorbic acid transporter activity(GO:0015229) sodium-dependent L-ascorbate transmembrane transporter activity(GO:0070890)
0.1	8.7	GO:0005200	structural constituent of cytoskeleton(GO:0005200)
0.1	0.4	GO:0036310	annealing helicase activity(GO:0036310)
0.1	1.0	GO:0003688	DNA replication origin binding(GO:0003688)
0.1	0.5	GO:0047498	calcium-dependent phospholipase A2 activity(GO:0047498)
0.1	0.9	GO:0032050	clathrin heavy chain binding(GO:0032050)
0.1	0.8	GO:0046934	phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol bisphosphate kinase activity(GO:0052813)
0.1	1.3	GO:0004679	AMP-activated protein kinase activity(GO:0004679)
0.1	0.6	GO:0015562	efflux transmembrane transporter activity(GO:0015562)
0.1	4.0	GO:0003743	translation initiation factor activity(GO:0003743)
0.1	0.3	GO:0016454	serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.1	1.1	GO:0004862	cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.1	0.3	GO:0015321	sodium-dependent phosphate transmembrane transporter activity(GO:0015321)
0.1	5.8	GO:0004197	cysteine-type endopeptidase activity(GO:0004197)
0.1	0.5	GO:0035033	histone deacetylase regulator activity(GO:0035033)
0.1	1.5	GO:0005521	lamin binding(GO:0005521)
0.1	0.2	GO:0008532	N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity(GO:0008532)
0.0	0.5	GO:0015288	porin activity(GO:0015288)
0.0	0.3	GO:0051011	microtubule minus-end binding(GO:0051011)
0.0	0.6	GO:0070324	thyroid hormone binding(GO:0070324)
0.0	0.1	GO:0005174	CD40 receptor binding(GO:0005174)
0.0	1.8	GO:0070064	proline-rich region binding(GO:0070064)
0.0	0.3	GO:0004691	cAMP-dependent protein kinase activity(GO:0004691)
0.0	0.8	GO:0004861	cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.0	0.6	GO:0050692	DBD domain binding(GO:0050692)
0.0	0.4	GO:0005412	glucose:sodium symporter activity(GO:0005412)
0.0	11.1	GO:0005549	odorant binding(GO:0005549)
0.0	0.6	GO:0048407	platelet-derived growth factor binding(GO:0048407)
0.0	0.4	GO:0086080	protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
0.0	2.0	GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0	0.8	GO:0004653	polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0	2.5	GO:0070888	E-box binding(GO:0070888)
0.0	1.3	GO:0008135	translation factor activity, RNA binding(GO:0008135)
0.0	0.5	GO:0017017	MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0	0.3	GO:0008454	alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.0	2.0	GO:0004601	peroxidase activity(GO:0004601)
0.0	0.6	GO:0017070	U6 snRNA binding(GO:0017070)
0.0	0.2	GO:0070728	leucine binding(GO:0070728)
0.0	4.1	GO:0017048	Rho GTPase binding(GO:0017048)
0.0	0.3	GO:0015129	lactate transmembrane transporter activity(GO:0015129)
0.0	0.4	GO:0008097	5S rRNA binding(GO:0008097)
0.0	0.6	GO:0008179	adenylate cyclase binding(GO:0008179)
0.0	0.2	GO:0061676	importin-alpha family protein binding(GO:0061676)
0.0	2.8	GO:0045309	protein phosphorylated amino acid binding(GO:0045309)
0.0	0.1	GO:0005134	interleukin-2 receptor binding(GO:0005134)
0.0	0.4	GO:0098641	cadherin binding involved in cell-cell adhesion(GO:0098641)
0.0	0.9	GO:0005201	extracellular matrix structural constituent(GO:0005201)
0.0	0.2	GO:0046912	transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.0	0.2	GO:0001515	opioid peptide activity(GO:0001515)
0.0	0.3	GO:0044323	retinoic acid-responsive element binding(GO:0044323)
0.0	0.9	GO:0070412	R-SMAD binding(GO:0070412)
0.0	0.1	GO:0016434	rRNA (cytosine) methyltransferase activity(GO:0016434)
0.0	1.9	GO:0015179	L-amino acid transmembrane transporter activity(GO:0015179)
0.0	4.2	GO:0017124	SH3 domain binding(GO:0017124)
0.0	3.8	GO:0042826	histone deacetylase binding(GO:0042826)
0.0	0.2	GO:0070097	delta-catenin binding(GO:0070097)
0.0	0.9	GO:0005385	zinc ion transmembrane transporter activity(GO:0005385)
0.0	3.5	GO:0047485	protein N-terminus binding(GO:0047485)
0.0	4.2	GO:0003735	structural constituent of ribosome(GO:0003735)
0.0	0.2	GO:0030229	very-low-density lipoprotein particle receptor activity(GO:0030229)
0.0	11.8	GO:0004984	olfactory receptor activity(GO:0004984)
0.0	0.1	GO:0019776	Atg8 ligase activity(GO:0019776)
0.0	0.1	GO:0016909	JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.0	0.2	GO:0070700	BMP receptor binding(GO:0070700)
0.0	0.3	GO:0048185	activin binding(GO:0048185)
0.0	0.4	GO:0016864	protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.0	0.2	GO:0070034	telomerase RNA binding(GO:0070034)
0.0	0.9	GO:0098811	transcriptional activator activity, RNA polymerase II transcription factor binding(GO:0001190) transcriptional repressor activity, RNA polymerase II activating transcription factor binding(GO:0098811)
0.0	0.7	GO:0043015	gamma-tubulin binding(GO:0043015)
0.0	0.2	GO:0045295	gamma-catenin binding(GO:0045295)
0.0	0.3	GO:0008641	small protein activating enzyme activity(GO:0008641)
0.0	0.1	GO:0034452	dynactin binding(GO:0034452)
0.0	0.3	GO:0034450	ubiquitin-ubiquitin ligase activity(GO:0034450)
0.0	0.3	GO:0009982	pseudouridine synthase activity(GO:0009982)
0.0	0.1	GO:0000990	transcription factor activity, core RNA polymerase binding(GO:0000990)
0.0	0.3	GO:0004383	guanylate cyclase activity(GO:0004383)
0.0	4.1	GO:0003924	GTPase activity(GO:0003924)
0.0	0.2	GO:0016783	sulfurtransferase activity(GO:0016783)
0.0	0.4	GO:0008139	nuclear localization sequence binding(GO:0008139)
0.0	1.3	GO:0005089	Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0	0.1	GO:0004568	chitinase activity(GO:0004568)
0.0	0.1	GO:0031802	type 5 metabotropic glutamate receptor binding(GO:0031802)
0.0	0.1	GO:0001609	G-protein coupled adenosine receptor activity(GO:0001609)
0.0	0.3	GO:0034237	protein kinase A regulatory subunit binding(GO:0034237)
0.0	0.6	GO:0050699	WW domain binding(GO:0050699)
0.0	0.4	GO:0005229	intracellular calcium activated chloride channel activity(GO:0005229)
0.0	7.8	GO:0001228	transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.0	0.6	GO:0001158	enhancer sequence-specific DNA binding(GO:0001158)
0.0	0.1	GO:0008353	RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.0	0.2	GO:0038036	sphingosine-1-phosphate receptor activity(GO:0038036)
0.0	1.5	GO:0004386	helicase activity(GO:0004386)
0.0	0.5	GO:0044183	protein binding involved in protein folding(GO:0044183)
0.0	4.1	GO:0030695	GTPase regulator activity(GO:0030695)
0.0	0.1	GO:0005111	type 2 fibroblast growth factor receptor binding(GO:0005111)
0.0	0.1	GO:0086006	voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006)
0.0	0.6	GO:0004715	non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0	0.6	GO:0030374	ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.0	0.3	GO:0046966	thyroid hormone receptor binding(GO:0046966)
0.0	0.2	GO:0005528	macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0	2.0	GO:0003714	transcription corepressor activity(GO:0003714)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.2	PID AR NONGENOMIC PATHWAY	Nongenotropic Androgen signaling
0.1	6.3	PID ATR PATHWAY	ATR signaling pathway
0.1	2.7	PID FANCONI PATHWAY	Fanconi anemia pathway
0.1	4.4	PID NCADHERIN PATHWAY	N-cadherin signaling events
0.1	2.8	PID P38 MKK3 6PATHWAY	p38 MAPK signaling pathway
0.1	3.4	PID AURORA A PATHWAY	Aurora A signaling
0.1	3.1	PID HIF2PATHWAY	HIF-2-alpha transcription factor network
0.1	1.3	PID LYMPH ANGIOGENESIS PATHWAY	VEGFR3 signaling in lymphatic endothelium
0.1	1.3	PID BCR 5PATHWAY	BCR signaling pathway
0.1	3.1	PID SYNDECAN 1 PATHWAY	Syndecan-1-mediated signaling events
0.1	2.4	ST WNT BETA CATENIN PATHWAY	Wnt/beta-catenin Pathway
0.1	2.9	PID IL6 7 PATHWAY	IL6-mediated signaling events
0.1	5.5	PID E2F PATHWAY	E2F transcription factor network
0.1	2.9	PID PLK1 PATHWAY	PLK1 signaling events
0.1	3.3	SIG PIP3 SIGNALING IN B LYMPHOCYTES	Genes related to PIP3 signaling in B lymphocytes
0.1	2.2	ST TUMOR NECROSIS FACTOR PATHWAY	Tumor Necrosis Factor Pathway.
0.1	2.4	PID SYNDECAN 2 PATHWAY	Syndecan-2-mediated signaling events
0.0	0.7	PID CIRCADIAN PATHWAY	Circadian rhythm pathway
0.0	1.5	PID IL12 STAT4 PATHWAY	IL12 signaling mediated by STAT4
0.0	1.5	PID MAPK TRK PATHWAY	Trk receptor signaling mediated by the MAPK pathway
0.0	9.7	NABA ECM GLYCOPROTEINS	Genes encoding structural ECM glycoproteins
0.0	1.2	PID IL2 PI3K PATHWAY	IL2 signaling events mediated by PI3K
0.0	3.0	PID AP1 PATHWAY	AP-1 transcription factor network
0.0	0.4	PID PI3KCI AKT PATHWAY	Class I PI3K signaling events mediated by Akt
0.0	3.2	PID REG GR PATHWAY	Glucocorticoid receptor regulatory network
0.0	0.6	ST ADRENERGIC	Adrenergic Pathway
0.0	3.0	PID TCR PATHWAY	TCR signaling in naïve CD4+ T cells
0.0	2.2	PID MET PATHWAY	Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.0	1.3	PID P38 ALPHA BETA DOWNSTREAM PATHWAY	Signaling mediated by p38-alpha and p38-beta
0.0	0.6	PID P38 MK2 PATHWAY	p38 signaling mediated by MAPKAP kinases
0.0	1.6	PID VEGFR1 2 PATHWAY	Signaling events mediated by VEGFR1 and VEGFR2
0.0	2.1	PID ILK PATHWAY	Integrin-linked kinase signaling
0.0	1.0	PID ALPHA SYNUCLEIN PATHWAY	Alpha-synuclein signaling
0.0	2.8	PID AR PATHWAY	Coregulation of Androgen receptor activity
0.0	0.3	PID ANTHRAX PATHWAY	Cellular roles of Anthrax toxin
0.0	1.7	PID CDC42 PATHWAY	CDC42 signaling events
0.0	0.6	PID MYC PATHWAY	C-MYC pathway
0.0	0.5	ST ERK1 ERK2 MAPK PATHWAY	ERK1/ERK2 MAPK Pathway
0.0	2.6	WNT SIGNALING	Genes related to Wnt-mediated signal transduction
0.0	1.2	PID RB 1PATHWAY	Regulation of retinoblastoma protein
0.0	1.2	NABA PROTEOGLYCANS	Genes encoding proteoglycans
0.0	2.5	PID RHOA REG PATHWAY	Regulation of RhoA activity
0.0	0.8	PID CONE PATHWAY	Visual signal transduction: Cones
0.0	1.6	PID CXCR4 PATHWAY	CXCR4-mediated signaling events
0.0	0.3	PID ATM PATHWAY	ATM pathway
0.0	1.0	PID MYC REPRESS PATHWAY	Validated targets of C-MYC transcriptional repression
0.0	0.5	PID FCER1 PATHWAY	Fc-epsilon receptor I signaling in mast cells
0.0	0.7	PID NFAT TFPATHWAY	Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0	0.7	PID PDGFRB PATHWAY	PDGFR-beta signaling pathway
0.0	0.4	PID NETRIN PATHWAY	Netrin-mediated signaling events
0.0	0.6	PID RAC1 REG PATHWAY	Regulation of RAC1 activity
0.0	0.6	PID HES HEY PATHWAY	Notch-mediated HES/HEY network
0.0	0.4	PID P75 NTR PATHWAY	p75(NTR)-mediated signaling
0.0	0.2	PID RHOA PATHWAY	RhoA signaling pathway
0.0	0.2	PID ECADHERIN STABILIZATION PATHWAY	Stabilization and expansion of the E-cadherin adherens junction
0.0	0.2	PID ARF 3PATHWAY	Arf1 pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.4	8.4	REACTOME INTRINSIC PATHWAY	Genes involved in Intrinsic Pathway
0.3	6.4	REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY	Genes involved in Post-chaperonin tubulin folding pathway
0.3	3.0	REACTOME HORMONE LIGAND BINDING RECEPTORS	Genes involved in Hormone ligand-binding receptors
0.3	4.1	REACTOME UNWINDING OF DNA	Genes involved in Unwinding of DNA
0.2	3.9	REACTOME PYRIMIDINE CATABOLISM	Genes involved in Pyrimidine catabolism
0.2	1.0	REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS	Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.1	5.8	REACTOME GENERATION OF SECOND MESSENGER MOLECULES	Genes involved in Generation of second messenger molecules
0.1	1.6	REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY	Genes involved in Regulation of the Fanconi anemia pathway
0.1	2.1	REACTOME PHOSPHORYLATION OF THE APC C	Genes involved in Phosphorylation of the APC/C
0.1	3.0	REACTOME PROLACTIN RECEPTOR SIGNALING	Genes involved in Prolactin receptor signaling
0.1	2.4	REACTOME RNA POL I TRANSCRIPTION TERMINATION	Genes involved in RNA Polymerase I Transcription Termination
0.1	3.9	REACTOME ERK MAPK TARGETS	Genes involved in ERK/MAPK targets
0.1	1.3	REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS	Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.1	2.1	REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS	Genes involved in Cell-extracellular matrix interactions
0.1	2.9	REACTOME AMINE COMPOUND SLC TRANSPORTERS	Genes involved in Amine compound SLC transporters
0.1	1.3	REACTOME REGULATION OF AMPK ACTIVITY VIA LKB1	Genes involved in Regulation of AMPK activity via LKB1
0.1	1.8	REACTOME PURINE SALVAGE	Genes involved in Purine salvage
0.1	0.9	REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION	Genes involved in Apoptosis induced DNA fragmentation
0.1	0.8	REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES	Genes involved in Chemokine receptors bind chemokines
0.1	2.5	REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION	Genes involved in Transport to the Golgi and subsequent modification
0.1	0.8	REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE	Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.1	3.0	REACTOME GLUTATHIONE CONJUGATION	Genes involved in Glutathione conjugation
0.1	2.4	REACTOME ADP SIGNALLING THROUGH P2RY1	Genes involved in ADP signalling through P2Y purinoceptor 1
0.1	1.0	REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS	Genes involved in Termination of O-glycan biosynthesis
0.1	2.9	REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS	Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.1	5.8	REACTOME MITOTIC PROMETAPHASE	Genes involved in Mitotic Prometaphase
0.1	0.8	REACTOME REGULATION OF SIGNALING BY CBL	Genes involved in Regulation of signaling by CBL
0.1	1.0	REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS	Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0	1.7	REACTOME KERATAN SULFATE BIOSYNTHESIS	Genes involved in Keratan sulfate biosynthesis
0.0	1.5	REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT	Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0	0.6	REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX	Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0	5.4	REACTOME PEPTIDE CHAIN ELONGATION	Genes involved in Peptide chain elongation
0.0	3.2	REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES	Genes involved in Loss of Nlp from mitotic centrosomes
0.0	2.9	REACTOME COLLAGEN FORMATION	Genes involved in Collagen formation
0.0	2.1	REACTOME AUTODEGRADATION OF CDH1 BY CDH1 APC C	Genes involved in Autodegradation of Cdh1 by Cdh1:APC/C
0.0	0.5	REACTOME REGULATORY RNA PATHWAYS	Genes involved in Regulatory RNA pathways
0.0	0.3	REACTOME FORMATION OF TRANSCRIPTION COUPLED NER TC NER REPAIR COMPLEX	Genes involved in Formation of transcription-coupled NER (TC-NER) repair complex
0.0	1.9	REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION	Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0	0.9	REACTOME ZINC TRANSPORTERS	Genes involved in Zinc transporters
0.0	0.5	REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX	Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0	1.4	REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT	Genes involved in ABC-family proteins mediated transport
0.0	1.0	REACTOME SIGNALING BY ROBO RECEPTOR	Genes involved in Signaling by Robo receptor
0.0	4.1	REACTOME MRNA SPLICING	Genes involved in mRNA Splicing
0.0	0.5	REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE	Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0	1.0	REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING	Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.0	0.1	REACTOME ADP SIGNALLING THROUGH P2RY12	Genes involved in ADP signalling through P2Y purinoceptor 12
0.0	1.1	REACTOME INTERACTION BETWEEN L1 AND ANKYRINS	Genes involved in Interaction between L1 and Ankyrins
0.0	4.6	REACTOME SIGNALING BY RHO GTPASES	Genes involved in Signaling by Rho GTPases
0.0	0.3	REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS	Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.0	0.1	REACTOME P2Y RECEPTORS	Genes involved in P2Y receptors
0.0	0.5	REACTOME PREFOLDIN MEDIATED TRANSFER OF SUBSTRATE TO CCT TRIC	Genes involved in Prefoldin mediated transfer of substrate to CCT/TriC
0.0	0.6	REACTOME O LINKED GLYCOSYLATION OF MUCINS	Genes involved in O-linked glycosylation of mucins
0.0	0.3	REACTOME TRAF6 MEDIATED IRF7 ACTIVATION	Genes involved in TRAF6 mediated IRF7 activation
0.0	0.3	REACTOME METABOLISM OF NON CODING RNA	Genes involved in Metabolism of non-coding RNA
0.0	0.8	REACTOME G1 PHASE	Genes involved in G1 Phase
0.0	0.2	REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS	Genes involved in Tandem pore domain potassium channels
0.0	0.3	REACTOME MEIOTIC RECOMBINATION	Genes involved in Meiotic Recombination
0.0	0.3	REACTOME REGULATION OF KIT SIGNALING	Genes involved in Regulation of KIT signaling
0.0	2.1	REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION	Genes involved in Factors involved in megakaryocyte development and platelet production
0.0	0.2	REACTOME RECYCLING PATHWAY OF L1	Genes involved in Recycling pathway of L1
0.0	0.2	REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION	Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.0	0.7	REACTOME MITOCHONDRIAL PROTEIN IMPORT	Genes involved in Mitochondrial Protein Import
0.0	0.3	REACTOME AMYLOIDS	Genes involved in Amyloids
0.0	0.2	REACTOME DCC MEDIATED ATTRACTIVE SIGNALING	Genes involved in DCC mediated attractive signaling

Results for Nkx6-1_Evx1_Hesx1

Z-value: 0.72

Motif logo

Transcription factors associated with Nkx6-1_Evx1_Hesx1

Activity-expression correlation:

Activity profile of Nkx6-1_Evx1_Hesx1 motif

Sorted Z-values of Nkx6-1_Evx1_Hesx1 motif

Top targets:

Network of associatons between targets according to the STRING database.

First level regulatory network of Nkx6-1_Evx1_Hesx1

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: