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GSE58827: Dynamics of the Mouse Liver

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Results for Nr1h4

Z-value: 1.69

Motif logo

Transcription factors associated with Nr1h4

Gene Symbol Gene ID Gene Info
ENSMUSG00000047638.16 nuclear receptor subfamily 1, group H, member 4

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Nr1h4mm39_v1_chr10_-_89369432_893694520.887.9e-13Click!

Activity profile of Nr1h4 motif

Sorted Z-values of Nr1h4 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr8_-_93806593 26.20 ENSMUST00000109582.3
carboxylesterase 1B
chr7_-_105249308 19.15 ENSMUST00000210531.2
ENSMUST00000033185.10
hemopexin
chr2_-_69172944 17.26 ENSMUST00000102709.8
ENSMUST00000102710.10
ENSMUST00000180142.2
ATP-binding cassette, sub-family B (MDR/TAP), member 11
chr17_-_32639936 15.15 ENSMUST00000170392.9
ENSMUST00000237165.2
ENSMUST00000235892.2
ENSMUST00000114455.3
peptidoglycan recognition protein 2
chr9_-_65330231 14.92 ENSMUST00000065894.7
solute carrier family 51, beta subunit
chr3_+_137983250 14.64 ENSMUST00000004232.10
alcohol dehydrogenase 1 (class I)
chr4_+_133280680 13.98 ENSMUST00000042706.3
nuclear receptor subfamily 0, group B, member 2
chr7_-_99345016 13.85 ENSMUST00000107086.9
solute carrier organic anion transporter family, member 2b1
chr1_+_67162176 13.59 ENSMUST00000027144.8
carbamoyl-phosphate synthetase 1
chr6_+_141575226 13.14 ENSMUST00000042812.9
solute carrier organic anion transporter family, member 1b2
chr15_-_82648376 13.10 ENSMUST00000055721.6
cytochrome P450, family 2, subfamily d, polypeptide 40
chr9_+_46179899 13.02 ENSMUST00000121598.8
apolipoprotein A-V
chr9_+_108539296 11.29 ENSMUST00000035222.6
solute carrier family 25 (mitochondrial carnitine/acylcarnitine translocase), member 20
chr11_-_116089595 11.11 ENSMUST00000072948.11
acyl-Coenzyme A oxidase 1, palmitoyl
chr11_-_116089866 11.03 ENSMUST00000066587.12
acyl-Coenzyme A oxidase 1, palmitoyl
chr19_+_38995463 10.76 ENSMUST00000025966.5
cytochrome P450, family 2, subfamily c, polypeptide 55
chr11_+_72326337 9.97 ENSMUST00000076443.10
gamma-glutamyltransferase 6
chr17_-_35081129 8.50 ENSMUST00000154526.8
complement factor B
chr17_-_57535003 8.45 ENSMUST00000177046.2
ENSMUST00000024988.15
complement component 3
chr17_-_35081456 8.20 ENSMUST00000025229.11
ENSMUST00000176203.9
ENSMUST00000128767.8
complement factor B
chr11_+_72326391 7.62 ENSMUST00000100903.3
gamma-glutamyltransferase 6
chrX_-_51254129 7.41 ENSMUST00000033450.3
glypican 4
chr11_+_72326358 6.91 ENSMUST00000108499.2
gamma-glutamyltransferase 6
chr14_-_30645711 6.79 ENSMUST00000006697.17
inter-alpha trypsin inhibitor, heavy chain 3
chr9_-_21900724 6.61 ENSMUST00000045726.8
ral guanine nucleotide dissociation stimulator-like 3
chr17_-_84154173 6.31 ENSMUST00000000687.9
3-hydroxyanthranilate 3,4-dioxygenase
chr7_-_44320244 6.29 ENSMUST00000048102.15
myosin, heavy polypeptide 14
chr9_+_107957621 6.26 ENSMUST00000035211.14
macrophage stimulating 1 (hepatocyte growth factor-like)
chr1_+_163979384 6.21 ENSMUST00000086040.6
coagulation factor V
chr9_+_107957640 6.12 ENSMUST00000162886.2
macrophage stimulating 1 (hepatocyte growth factor-like)
chr7_-_30755007 6.10 ENSMUST00000206474.2
ENSMUST00000205807.2
ENSMUST00000039909.13
ENSMUST00000206305.2
ENSMUST00000205439.2
FXYD domain-containing ion transport regulator 1
chr11_+_97576619 5.95 ENSMUST00000107584.8
ENSMUST00000107585.9
CDGSH iron sulfur domain 3
chr14_-_30645503 5.26 ENSMUST00000227995.2
inter-alpha trypsin inhibitor, heavy chain 3
chr16_-_22847808 5.17 ENSMUST00000115349.9
kininogen 2
chr11_+_97576724 5.12 ENSMUST00000107583.3
CDGSH iron sulfur domain 3
chr16_-_22847760 5.10 ENSMUST00000039338.13
kininogen 2
chr13_+_25127127 5.08 ENSMUST00000021773.13
glycosylphosphatidylinositol specific phospholipase D1
chr16_-_22847829 4.98 ENSMUST00000100046.9
kininogen 2
chr17_-_84154196 4.90 ENSMUST00000234214.2
3-hydroxyanthranilate 3,4-dioxygenase
chr8_+_13110921 4.79 ENSMUST00000211363.2
ENSMUST00000033822.4
protein Z, vitamin K-dependent plasma glycoprotein
chr4_-_141345549 4.76 ENSMUST00000053263.9
transmembrane protein 82
chr13_+_91889626 4.73 ENSMUST00000022120.5
acyl-CoA thioesterase 12
chr7_-_126944578 4.69 ENSMUST00000060783.7
zinc finger protein 768
chr17_-_79328157 4.57 ENSMUST00000168887.8
ENSMUST00000119284.8
protein kinase D3
chr10_+_23770586 4.49 ENSMUST00000041416.8
vanin 1
chr19_+_44980565 4.46 ENSMUST00000179305.2
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4G
chr5_+_137568982 4.41 ENSMUST00000196471.5
ENSMUST00000198783.5
transferrin receptor 2
chr9_-_106353792 4.37 ENSMUST00000214682.2
ENSMUST00000112479.9
poly (ADP-ribose) polymerase family, member 3
chr10_-_80934708 4.35 ENSMUST00000117422.2
cAMP responsive element binding protein 3-like 3
chr15_-_82678490 4.25 ENSMUST00000006094.6
cytochrome P450, family 2, subfamily d, polypeptide 26
chr19_-_38113056 4.17 ENSMUST00000236283.2
retinol binding protein 4, plasma
chr7_-_30754223 4.13 ENSMUST00000206012.2
ENSMUST00000108110.5
FXYD domain-containing ion transport regulator 1
chr11_+_101442961 4.07 ENSMUST00000103099.8
NBR1, autophagy cargo receptor
chr1_-_162687254 3.96 ENSMUST00000131058.8
flavin containing monooxygenase 1
chr7_-_30754240 3.95 ENSMUST00000206860.2
ENSMUST00000071697.11
FXYD domain-containing ion transport regulator 1
chr17_-_87573294 3.91 ENSMUST00000145895.8
ENSMUST00000129616.8
ENSMUST00000155904.2
ENSMUST00000151155.8
ENSMUST00000144236.9
ENSMUST00000024963.11
multiple coagulation factor deficiency 2
chr7_-_30754193 3.87 ENSMUST00000205778.2
FXYD domain-containing ion transport regulator 1
chr10_+_116137277 3.85 ENSMUST00000092167.7
protein tyrosine phosphatase, receptor type, B
chr16_-_22848153 3.79 ENSMUST00000232459.2
kininogen 2
chr1_-_162687369 3.66 ENSMUST00000193078.6
flavin containing monooxygenase 1
chr1_+_171052623 3.61 ENSMUST00000111321.8
ENSMUST00000005824.12
ENSMUST00000111320.8
ENSMUST00000111319.2
apolipoprotein A-II
chr10_-_78134026 3.60 ENSMUST00000105389.8
1-acylglycerol-3-phosphate O-acyltransferase 3
chr3_+_121761471 3.31 ENSMUST00000196479.5
ENSMUST00000197155.5
Rho GTPase activating protein 29
chr11_-_100595019 3.29 ENSMUST00000017974.13
DEXH (Asp-Glu-X-His) box polypeptide 58
chr17_+_25352353 3.26 ENSMUST00000162862.3
ENSMUST00000040729.9
chloride channel, voltage-sensitive 7
chr17_-_25459086 3.19 ENSMUST00000038973.7
ENSMUST00000115154.11
N-acetylglucosamine-1-phosphotransferase, gamma subunit
chr2_-_174305856 3.10 ENSMUST00000016396.8
ATP synthase, H+ transporting, mitochondrial F1 complex, epsilon subunit
chr13_+_41013230 3.05 ENSMUST00000110191.10
glucosaminyl (N-acetyl) transferase 2, I-branching enzyme
chr10_+_43777777 2.99 ENSMUST00000054418.12
reticulon 4 interacting protein 1
chr11_+_101443014 2.94 ENSMUST00000147239.8
NBR1, autophagy cargo receptor
chr11_+_66915969 2.83 ENSMUST00000079077.12
ENSMUST00000061786.6
transmembrane protein 220
chr3_-_120965327 2.79 ENSMUST00000170781.2
ENSMUST00000039761.12
ENSMUST00000106467.8
ENSMUST00000106466.10
ENSMUST00000164925.9
RWD domain containing 3
chr9_+_44018583 2.74 ENSMUST00000152956.8
ENSMUST00000114815.3
ENSMUST00000206295.2
ENSMUST00000206769.2
ENSMUST00000205500.2
C1q and tumor necrosis factor related protein 5
chr15_-_31367872 2.69 ENSMUST00000123325.9
ankyrin repeat domain 33B
chr13_+_41040657 2.68 ENSMUST00000069958.15
glucosaminyl (N-acetyl) transferase 2, I-branching enzyme
chr9_+_21914083 2.66 ENSMUST00000216344.2
protein kinase C substrate 80K-H
chr7_+_18725170 2.63 ENSMUST00000059331.9
ENSMUST00000131087.2
Myb-related transcription factor, partner of profilin
chr15_-_31367668 2.59 ENSMUST00000110410.10
ENSMUST00000076942.5
ankyrin repeat domain 33B
chr17_-_74354844 2.56 ENSMUST00000043458.9
steroid 5 alpha-reductase 2
chr11_+_70410445 2.55 ENSMUST00000179000.2
glycolipid transfer protein domain containing 2
chr15_+_76264695 2.41 ENSMUST00000096385.11
ENSMUST00000160728.8
maestro heat-like repeat family member 1
chr9_-_21913833 2.38 ENSMUST00000115336.10
outer dynein arm docking complex subunit 3
chr9_+_44018551 2.37 ENSMUST00000114821.9
ENSMUST00000114818.9
C1q and tumor necrosis factor related protein 5
chr11_+_101443674 2.32 ENSMUST00000107213.8
ENSMUST00000107208.8
ENSMUST00000107212.8
ENSMUST00000127421.8
NBR1, autophagy cargo receptor
chr9_+_21279802 2.23 ENSMUST00000214474.2
interleukin enhancer binding factor 3
chr15_+_102010632 2.23 ENSMUST00000229592.2
tensin 2
chr10_-_67384898 2.22 ENSMUST00000075686.7
2-aminoethanethiol (cysteamine) dioxygenase
chr9_-_59260713 2.20 ENSMUST00000026265.8
Bardet-Biedl syndrome 4 (human)
chr8_+_89247976 2.17 ENSMUST00000034086.13
naked cuticle 1
chr9_+_21914334 2.17 ENSMUST00000115331.10
protein kinase C substrate 80K-H
chr16_-_20549294 2.13 ENSMUST00000231826.2
ENSMUST00000076422.13
ENSMUST00000232217.2
thrombopoietin
chr9_-_21913896 2.11 ENSMUST00000044926.6
outer dynein arm docking complex subunit 3
chr11_-_120715351 2.07 ENSMUST00000055655.9
fatty acid synthase
chr2_-_130480014 2.05 ENSMUST00000089561.10
ENSMUST00000110260.8
leucine zipper, putative tumor suppressor family member 3
chr3_+_154302311 2.00 ENSMUST00000192462.6
ENSMUST00000029850.15
crystallin, zeta
chr1_-_162641495 1.98 ENSMUST00000144916.8
ENSMUST00000140274.2
flavin containing monooxygenase 4
chr15_+_80556023 1.94 ENSMUST00000023044.7
family with sequence similarity 83, member F
chr9_+_21914296 1.91 ENSMUST00000003493.9
protein kinase C substrate 80K-H
chr10_+_4561974 1.91 ENSMUST00000105590.8
ENSMUST00000067086.14
estrogen receptor 1 (alpha)
chrM_+_8603 1.77 ENSMUST00000082409.1
mitochondrially encoded cytochrome c oxidase III
chr9_+_56902172 1.65 ENSMUST00000034832.8
protein tyrosine phosphatase, non-receptor type 9
chr6_+_72391283 1.64 ENSMUST00000065906.9
gamma-glutamyl carboxylase
chr19_-_6919755 1.62 ENSMUST00000099782.10
G protein-coupled receptor 137
chr5_-_147662798 1.57 ENSMUST00000110529.6
ENSMUST00000031653.12
FMS-like tyrosine kinase 1
chr9_-_63285080 1.56 ENSMUST00000034920.11
mitogen-activated protein kinase kinase 5
chrX_-_137985960 1.48 ENSMUST00000033626.15
ENSMUST00000060824.4
serine (or cysteine) peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 7
chr12_+_76593799 1.45 ENSMUST00000218380.2
ENSMUST00000219751.2
pleckstrin homology domain containing, family G (with RhoGef domain) member 3
chr9_-_106353303 1.39 ENSMUST00000156426.8
poly (ADP-ribose) polymerase family, member 3
chr9_+_44018520 1.39 ENSMUST00000114816.8
C1q and tumor necrosis factor related protein 5
chr7_-_45362867 1.38 ENSMUST00000211340.2
sphingosine kinase 2
chr2_-_90748331 1.35 ENSMUST00000111461.13
protein tyrosine phosphatase, mitochondrial 1
chrX_+_20714782 1.33 ENSMUST00000001155.11
ENSMUST00000122312.8
ENSMUST00000120356.8
ENSMUST00000122850.2
Araf proto-oncogene, serine/threonine kinase
chr8_+_85807369 1.28 ENSMUST00000079764.14
WD repeat domain 83 opposite strand
chr7_+_138968988 1.25 ENSMUST00000106098.8
ENSMUST00000026550.14
inositol polyphosphate-5-phosphatase A
chr4_-_133360749 1.24 ENSMUST00000084238.5
zinc finger, DHHC domain containing 18
chr1_-_43235914 1.22 ENSMUST00000187357.2
four and a half LIM domains 2
chr4_-_135699885 1.21 ENSMUST00000067567.5
lysophospholipase 2
chr10_-_89568106 1.19 ENSMUST00000020109.5
ARP6 actin-related protein 6
chrX_-_137985979 1.18 ENSMUST00000152457.2
serine (or cysteine) peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 7
chr9_+_21914513 1.15 ENSMUST00000215795.2
protein kinase C substrate 80K-H
chr13_-_39144475 1.13 ENSMUST00000225331.2
ENSMUST00000224645.2
ENSMUST00000167513.3
ENSMUST00000225568.2
solute carrier family 35, member B3
chr6_-_29380423 1.10 ENSMUST00000147483.3
opsin 1 (cone pigments), short-wave-sensitive (color blindness, tritan)
chr15_-_77811935 1.08 ENSMUST00000174529.2
ENSMUST00000173631.8
thioredoxin 2
chr9_-_20791012 1.07 ENSMUST00000043726.8
angiopoietin-like 6
chr17_+_25459138 1.07 ENSMUST00000063574.7
TSR3 20S rRNA accumulation
chr9_-_50663648 1.06 ENSMUST00000217159.2
heat shock protein 2
chr12_-_16660960 1.01 ENSMUST00000239165.2
ENSMUST00000111067.10
lipin 1
chr14_-_31552335 1.01 ENSMUST00000228037.2
ankyrin repeat domain 28
chr12_-_103597663 0.97 ENSMUST00000121625.2
ENSMUST00000044231.12
serine (or cysteine) peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10
chr5_-_31359276 0.97 ENSMUST00000031562.11
zinc finger protein 513
chrX_-_18327610 0.94 ENSMUST00000044188.5
divergent protein kinase domain 2B
chr15_-_103231921 0.91 ENSMUST00000229551.2
zinc finger protein 385A
chrX_-_138683102 0.89 ENSMUST00000101217.4
ripply transcriptional repressor 1
chr6_-_86770504 0.88 ENSMUST00000204441.3
ENSMUST00000204398.2
ENSMUST00000001187.15
annexin A4
chr7_+_18910340 0.87 ENSMUST00000117338.8
echinoderm microtubule associated protein like 2
chr1_-_171074652 0.85 ENSMUST00000013737.13
ENSMUST00000111318.8
NADH:ubiquinone oxidoreductase core subunit S2
chr3_-_107424637 0.83 ENSMUST00000166892.2
solute carrier family 6 (neurotransmitter transporter), member 17
chr11_-_63970270 0.82 ENSMUST00000049091.9
heme A:farnesyltransferase cytochrome c oxidase assembly factor 10
chr1_-_63215952 0.81 ENSMUST00000185412.7
ENSMUST00000027111.15
ENSMUST00000189664.2
NADH:ubiquinone oxidoreductase core subunit S1
chr7_-_4974167 0.80 ENSMUST00000133272.2
SH3 domain binding kinase family, member 3
chr11_+_75404356 0.79 ENSMUST00000042808.13
ENSMUST00000118243.2
scavenger receptor class F, member 1
chr7_+_16044336 0.78 ENSMUST00000136781.2
BCL2 binding component 3
chr10_-_23226034 0.77 ENSMUST00000219315.2
EYA transcriptional coactivator and phosphatase 4
chr6_-_24528012 0.77 ENSMUST00000023851.9
NADH:ubiquinone oxidoreductase subunit A5
chr11_+_5905693 0.71 ENSMUST00000002818.9
YKT6 v-SNARE homolog (S. cerevisiae)
chr3_+_137329433 0.70 ENSMUST00000053855.8
DNA-damage-inducible transcript 4-like
chr16_-_94171556 0.69 ENSMUST00000113906.9
phosphatidylinositol glycan anchor biosynthesis, class P
chr2_-_120183575 0.68 ENSMUST00000028752.8
ENSMUST00000102501.10
VPS39 HOPS complex subunit
chr13_-_40882417 0.65 ENSMUST00000225180.2
transcription factor AP-2, alpha
chr5_-_129916283 0.63 ENSMUST00000094280.4
coiled-coil-helix-coiled-coil-helix domain containing 2
chr7_+_44091822 0.63 ENSMUST00000058667.15
leucine rich repeat containing 4B
chr2_+_32511762 0.62 ENSMUST00000113278.9
adenylate kinase 1
chr2_+_83791847 0.61 ENSMUST00000178960.2
predicted gene 13693
chr7_-_4973960 0.61 ENSMUST00000144863.8
SH3 domain binding kinase family, member 3
chrX_+_76554608 0.60 ENSMUST00000088217.12
transducin (beta)-like 1 X-linked
chrX_-_101687813 0.59 ENSMUST00000052012.14
ENSMUST00000043596.12
ENSMUST00000119229.8
ENSMUST00000122022.8
ENSMUST00000120270.8
ENSMUST00000113611.3
phosphorylase kinase alpha 1
chr17_+_24888641 0.59 ENSMUST00000234956.2
zinc finger protein 598
chr2_+_128907854 0.58 ENSMUST00000035812.14
tubulin tyrosine ligase
chr17_+_24888704 0.58 ENSMUST00000047179.7
zinc finger protein 598
chr1_+_36550948 0.56 ENSMUST00000001166.14
ENSMUST00000097776.4
cyclin M3
chr15_+_101371353 0.53 ENSMUST00000088049.5
keratin 86
chr6_-_129600798 0.53 ENSMUST00000095412.10
killer cell lectin-like receptor subfamily K, member 1
chr9_-_106533279 0.52 ENSMUST00000023959.13
ENSMUST00000201681.2
glutamate receptor, metabotropic 2
chr1_+_152830720 0.52 ENSMUST00000043313.15
ENSMUST00000186621.2
nicotinamide nucleotide adenylyltransferase 2
chr6_-_41752111 0.52 ENSMUST00000214976.3
olfactory receptor 459
chr6_-_29380467 0.50 ENSMUST00000080428.13
opsin 1 (cone pigments), short-wave-sensitive (color blindness, tritan)
chr5_-_31359559 0.50 ENSMUST00000202929.2
ENSMUST00000201231.2
ENSMUST00000114590.8
zinc finger protein 513
chr4_+_42917228 0.48 ENSMUST00000107976.9
ENSMUST00000069184.9
PHD finger protein 24
chr15_-_90934021 0.48 ENSMUST00000109287.4
ENSMUST00000067205.16
ENSMUST00000088614.13
kinesin family member 21A
chr15_-_90934059 0.46 ENSMUST00000109288.9
ENSMUST00000100304.11
kinesin family member 21A
chr15_-_98465516 0.44 ENSMUST00000012104.7
cyclin T1
chr12_-_87346479 0.42 ENSMUST00000125733.8
isthmin 2
chr6_+_24528143 0.42 ENSMUST00000031696.10
ankyrin repeat and SOCS box-containing 15
chr4_-_135699205 0.41 ENSMUST00000105852.8
lysophospholipase 2
chr1_+_92934050 0.41 ENSMUST00000059676.5
aquaporin 12
chr1_-_63215812 0.40 ENSMUST00000185847.2
ENSMUST00000185732.7
ENSMUST00000188370.7
ENSMUST00000168099.9
NADH:ubiquinone oxidoreductase core subunit S1
chr3_+_137329791 0.40 ENSMUST00000165845.2
DNA-damage-inducible transcript 4-like
chr9_+_50664207 0.39 ENSMUST00000034562.9
crystallin, alpha B
chr17_-_5490504 0.39 ENSMUST00000005053.14
ENSMUST00000185896.2
ENSMUST00000188282.7
transmembrane protein 242
chr9_+_50664288 0.39 ENSMUST00000214962.2
ENSMUST00000216755.2
crystallin, alpha B
chr2_+_177404691 0.38 ENSMUST00000119838.9
predicted gene 14322
chr7_+_128213084 0.37 ENSMUST00000043138.13
inositol polyphosphate-5-phosphatase F
chr2_-_152793376 0.37 ENSMUST00000123121.9
dual specificity phosphatase-like 15
chr8_+_93400916 0.35 ENSMUST00000034185.13
Iroquois homeobox 6
chr12_+_105672227 0.33 ENSMUST00000040876.7
adenylate kinase 7
chr4_-_133399909 0.33 ENSMUST00000062118.11
ENSMUST00000067902.13
phosphatidylinositol glycan anchor biosynthesis, class V
chr1_-_153683908 0.33 ENSMUST00000141249.8
regulator of G-protein signaling like 1
chr19_-_24202344 0.32 ENSMUST00000099558.5
ENSMUST00000232956.2
tight junction protein 2
chr5_-_5529119 0.32 ENSMUST00000115447.2
PTTG1IP family member 2
chr6_-_41751648 0.32 ENSMUST00000214752.2
olfactory receptor 459
chr13_+_38041910 0.30 ENSMUST00000138110.8
ras responsive element binding protein 1
chr5_-_37494179 0.29 ENSMUST00000114148.2
EvC ciliary complex subunit 1
chr17_-_57348647 0.28 ENSMUST00000169012.2
ENSMUST00000058661.14
solute carrier family 25, member 41
chr14_+_53791444 0.25 ENSMUST00000198297.2
T cell receptor alpha variable 14-1
chr9_-_50663571 0.23 ENSMUST00000042790.5
heat shock protein 2
chr4_-_15149755 0.22 ENSMUST00000108273.2
N-terminal EF-hand calcium binding protein 1
chr5_-_37494213 0.21 ENSMUST00000031005.11
EvC ciliary complex subunit 1
chr10_+_80707669 0.20 ENSMUST00000219817.2
transmembrane protease, serine 9
chr6_-_129600812 0.20 ENSMUST00000168919.8
killer cell lectin-like receptor subfamily K, member 1
chr4_+_53440389 0.19 ENSMUST00000107646.9
ENSMUST00000102911.10
solute carrier family 44, member 1

Network of associatons between targets according to the STRING database.

First level regulatory network of Nr1h4

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
4.2 16.6 GO:0010901 regulation of very-low-density lipoprotein particle remodeling(GO:0010901)
3.7 22.1 GO:0033540 fatty acid beta-oxidation using acyl-CoA oxidase(GO:0033540)
3.7 14.6 GO:0006069 ethanol oxidation(GO:0006069)
2.8 13.9 GO:0071718 sodium-independent icosanoid transport(GO:0071718)
2.7 19.2 GO:0060332 positive regulation of humoral immune response mediated by circulating immunoglobulin(GO:0002925) heme transport(GO:0015886) positive regulation of response to interferon-gamma(GO:0060332) positive regulation of interferon-gamma-mediated signaling pathway(GO:0060335)
2.5 15.1 GO:0000270 peptidoglycan metabolic process(GO:0000270) peptidoglycan catabolic process(GO:0009253) negative regulation of natural killer cell differentiation(GO:0032824) negative regulation of natural killer cell differentiation involved in immune response(GO:0032827)
2.5 17.3 GO:0046618 drug export(GO:0046618)
2.1 8.4 GO:0001970 positive regulation of activation of membrane attack complex(GO:0001970)
1.9 13.6 GO:0019856 'de novo' pyrimidine nucleobase biosynthetic process(GO:0006207) pyrimidine nucleobase biosynthetic process(GO:0019856)
1.7 24.5 GO:0006751 glutathione catabolic process(GO:0006751)
1.6 18.1 GO:1903797 positive regulation of sodium ion export(GO:1903275) positive regulation of sodium ion export from cell(GO:1903278) positive regulation of inorganic anion transmembrane transport(GO:1903797)
1.4 12.4 GO:0060763 mammary duct terminal end bud growth(GO:0060763)
1.3 5.1 GO:0010982 GPI anchor release(GO:0006507) regulation of high-density lipoprotein particle clearance(GO:0010982)
1.3 11.3 GO:0015879 carnitine transport(GO:0015879)
1.2 11.2 GO:0046874 quinolinate metabolic process(GO:0046874)
1.1 14.9 GO:0070863 positive regulation of protein glycosylation(GO:0060050) positive regulation of protein exit from endoplasmic reticulum(GO:0070863)
1.1 16.7 GO:0006957 complement activation, alternative pathway(GO:0006957)
1.1 3.2 GO:0016256 N-glycan processing to lysosome(GO:0016256)
1.0 5.8 GO:1990166 protein localization to site of double-strand break(GO:1990166)
0.9 2.8 GO:1900039 positive regulation of cellular response to hypoxia(GO:1900039) regulation of hypoxia-inducible factor-1alpha signaling pathway(GO:1902071)
0.9 10.8 GO:0043651 linoleic acid metabolic process(GO:0043651)
0.9 2.7 GO:0033189 response to vitamin A(GO:0033189)
0.8 4.2 GO:0048807 female genitalia morphogenesis(GO:0048807)
0.8 13.1 GO:0006857 oligopeptide transport(GO:0006857)
0.8 5.7 GO:0036438 maintenance of lens transparency(GO:0036438)
0.7 4.6 GO:0089700 protein kinase D signaling(GO:0089700)
0.6 2.2 GO:0038108 negative regulation of appetite by leptin-mediated signaling pathway(GO:0038108)
0.5 3.3 GO:1900245 negative regulation of MDA-5 signaling pathway(GO:0039534) positive regulation of MDA-5 signaling pathway(GO:1900245)
0.5 2.1 GO:0038163 thrombopoietin-mediated signaling pathway(GO:0038163)
0.4 1.6 GO:0017187 peptidyl-glutamic acid carboxylation(GO:0017187)
0.4 7.6 GO:0070995 NADPH oxidation(GO:0070995)
0.4 4.4 GO:0097460 ferrous iron import into cell(GO:0097460) ferrous iron import across plasma membrane(GO:0098707)
0.4 1.6 GO:0045415 negative regulation of interleukin-8 biosynthetic process(GO:0045415)
0.4 23.8 GO:1900047 negative regulation of blood coagulation(GO:0030195) negative regulation of hemostasis(GO:1900047)
0.3 1.4 GO:0006669 sphinganine-1-phosphate biosynthetic process(GO:0006669)
0.3 2.6 GO:0061370 testosterone biosynthetic process(GO:0061370)
0.3 1.9 GO:0060523 prostate epithelial cord elongation(GO:0060523)
0.3 7.9 GO:0006491 N-glycan processing(GO:0006491)
0.3 1.2 GO:0055014 atrial cardiac muscle cell differentiation(GO:0055011) atrial cardiac muscle cell development(GO:0055014)
0.3 4.4 GO:1990440 positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress(GO:1990440)
0.3 12.0 GO:0030212 hyaluronan metabolic process(GO:0030212)
0.3 2.0 GO:0042737 drug catabolic process(GO:0042737)
0.3 1.6 GO:0002084 protein depalmitoylation(GO:0002084) macromolecule depalmitoylation(GO:0098734)
0.3 17.4 GO:0019369 arachidonic acid metabolic process(GO:0019369)
0.3 4.5 GO:2000400 positive regulation of T cell differentiation in thymus(GO:0033089) positive regulation of thymocyte aggregation(GO:2000400)
0.3 2.1 GO:0008611 ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) ether biosynthetic process(GO:1901503)
0.2 0.7 GO:0030887 positive regulation of myeloid dendritic cell activation(GO:0030887)
0.2 2.2 GO:0038031 non-canonical Wnt signaling pathway via MAPK cascade(GO:0038030) non-canonical Wnt signaling pathway via JNK cascade(GO:0038031)
0.2 0.9 GO:0010609 mRNA localization resulting in posttranscriptional regulation of gene expression(GO:0010609) positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902164)
0.2 1.6 GO:0048050 post-embryonic eye morphogenesis(GO:0048050) post-embryonic camera-type eye morphogenesis(GO:0048597)
0.2 1.2 GO:0072344 rescue of stalled ribosome(GO:0072344)
0.2 0.8 GO:0018343 protein farnesylation(GO:0018343)
0.1 1.3 GO:0032049 cardiolipin biosynthetic process(GO:0032049)
0.1 6.3 GO:0071625 vocalization behavior(GO:0071625)
0.1 0.7 GO:1902774 late endosome to lysosome transport(GO:1902774)
0.1 4.7 GO:0006084 acetyl-CoA metabolic process(GO:0006084)
0.1 0.7 GO:0003409 optic cup structural organization(GO:0003409)
0.1 14.0 GO:0032024 positive regulation of insulin secretion(GO:0032024)
0.1 0.9 GO:0010968 regulation of microtubule nucleation(GO:0010968)
0.1 9.3 GO:0045668 negative regulation of osteoblast differentiation(GO:0045668)
0.1 1.3 GO:0007525 somatic muscle development(GO:0007525)
0.1 1.6 GO:0018298 protein-chromophore linkage(GO:0018298)
0.1 0.8 GO:1900740 positive regulation of thymocyte apoptotic process(GO:0070245) regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900739) positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900740)
0.1 0.8 GO:0015820 branched-chain amino acid transport(GO:0015803) leucine transport(GO:0015820)
0.1 0.6 GO:0006172 ADP biosynthetic process(GO:0006172) inosine biosynthetic process(GO:0046103)
0.1 0.9 GO:2000483 negative regulation of interleukin-8 secretion(GO:2000483)
0.1 1.1 GO:0018904 glycerol ether metabolic process(GO:0006662) ether metabolic process(GO:0018904)
0.1 1.0 GO:0006642 triglyceride mobilization(GO:0006642)
0.1 3.1 GO:0015986 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.1 2.0 GO:0042178 xenobiotic catabolic process(GO:0042178)
0.1 0.5 GO:0034627 nicotinamide nucleotide biosynthetic process from aspartate(GO:0019355) 'de novo' NAD biosynthetic process(GO:0034627) 'de novo' NAD biosynthetic process from aspartate(GO:0034628)
0.1 4.5 GO:0050919 negative chemotaxis(GO:0050919)
0.1 0.8 GO:0007021 tubulin complex assembly(GO:0007021)
0.1 0.8 GO:0048680 positive regulation of axon regeneration(GO:0048680)
0.1 6.2 GO:0070206 protein trimerization(GO:0070206)
0.1 0.9 GO:0016576 histone dephosphorylation(GO:0016576)
0.1 1.4 GO:0014850 response to muscle activity(GO:0014850)
0.1 1.2 GO:0046855 inositol phosphate dephosphorylation(GO:0046855)
0.1 0.9 GO:0032525 somite rostral/caudal axis specification(GO:0032525)
0.1 3.3 GO:0009268 response to pH(GO:0009268)
0.1 0.4 GO:0031161 phosphatidylinositol catabolic process(GO:0031161)
0.1 0.3 GO:1903691 positive regulation of wound healing, spreading of epidermal cells(GO:1903691)
0.0 0.3 GO:2001205 negative regulation of osteoclast development(GO:2001205)
0.0 0.6 GO:1900037 regulation of cellular response to hypoxia(GO:1900037)
0.0 0.4 GO:1901409 positive regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901409)
0.0 3.8 GO:0022904 respiratory electron transport chain(GO:0022904)
0.0 1.2 GO:0018345 protein palmitoylation(GO:0018345)
0.0 2.2 GO:0045071 negative regulation of viral genome replication(GO:0045071)
0.0 0.3 GO:0060040 retinal bipolar neuron differentiation(GO:0060040)
0.0 0.2 GO:0015871 choline transport(GO:0015871)
0.0 0.7 GO:0006903 vesicle targeting(GO:0006903)
0.0 0.1 GO:2001025 positive regulation of response to drug(GO:2001025)
0.0 1.0 GO:0006505 GPI anchor metabolic process(GO:0006505)
0.0 0.2 GO:0031639 plasminogen activation(GO:0031639)
0.0 1.1 GO:0030490 maturation of SSU-rRNA(GO:0030490)
0.0 0.3 GO:0003351 epithelial cilium movement(GO:0003351)
0.0 0.5 GO:0003416 endochondral bone growth(GO:0003416) bone growth(GO:0098868)
0.0 0.5 GO:0014047 glutamate secretion(GO:0014047)
0.0 1.3 GO:0032006 regulation of TOR signaling(GO:0032006)
0.0 2.3 GO:0007596 blood coagulation(GO:0007596)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.6 7.9 GO:0017177 glucosidase II complex(GO:0017177)
1.0 17.3 GO:0046581 intercellular canaliculus(GO:0046581)
0.9 6.3 GO:0097513 myosin II filament(GO:0097513)
0.7 16.6 GO:0042627 chylomicron(GO:0042627)
0.3 3.1 GO:0000275 mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275) proton-transporting ATP synthase complex, catalytic core F(1)(GO:0045261)
0.3 4.4 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.3 1.9 GO:0097550 transcriptional preinitiation complex(GO:0097550)
0.3 5.1 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.2 13.6 GO:0009295 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.2 6.2 GO:0031091 platelet alpha granule(GO:0031091)
0.2 22.1 GO:0005778 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.2 61.3 GO:0072562 blood microparticle(GO:0072562)
0.2 9.3 GO:0000407 pre-autophagosomal structure(GO:0000407)
0.2 14.5 GO:0034707 chloride channel complex(GO:0034707)
0.2 4.7 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.2 2.2 GO:0034464 BBSome(GO:0034464)
0.2 13.9 GO:0009925 basal plasma membrane(GO:0009925)
0.1 2.6 GO:0070852 cell body fiber(GO:0070852)
0.1 5.8 GO:0035861 site of double-strand break(GO:0035861)
0.1 0.7 GO:0097441 basilar dendrite(GO:0097441)
0.1 0.6 GO:0005964 phosphorylase kinase complex(GO:0005964)
0.1 0.3 GO:0031501 mannosyltransferase complex(GO:0031501)
0.1 2.2 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.1 4.2 GO:0016328 lateral plasma membrane(GO:0016328)
0.1 2.8 GO:0005747 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.1 0.7 GO:0030897 HOPS complex(GO:0030897)
0.0 0.4 GO:0008024 cyclin/CDK positive transcription elongation factor complex(GO:0008024)
0.0 0.6 GO:0001520 outer dense fiber(GO:0001520)
0.0 10.0 GO:0031225 anchored component of membrane(GO:0031225)
0.0 0.6 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.0 12.1 GO:0016323 basolateral plasma membrane(GO:0016323)
0.0 0.6 GO:0071006 U2-type catalytic step 1 spliceosome(GO:0071006)
0.0 0.8 GO:0097512 cardiac myofibril(GO:0097512)
0.0 0.7 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.0 1.2 GO:0031430 M band(GO:0031430)
0.0 0.8 GO:0070069 cytochrome complex(GO:0070069)
0.0 1.1 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.0 0.7 GO:0031305 integral component of mitochondrial inner membrane(GO:0031305)
0.0 0.5 GO:0045095 keratin filament(GO:0045095)
0.0 4.6 GO:0005765 lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852)
0.0 11.6 GO:0005740 mitochondrial envelope(GO:0005740)
0.0 5.4 GO:0043235 receptor complex(GO:0043235)
0.0 0.2 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.0 0.9 GO:0005871 kinesin complex(GO:0005871)
0.0 0.3 GO:0005921 gap junction(GO:0005921)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
4.9 14.6 GO:0004024 alcohol dehydrogenase activity, zinc-dependent(GO:0004024)
4.5 13.6 GO:0004088 carbamoyl-phosphate synthase (ammonia) activity(GO:0004087) carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity(GO:0004088)
3.2 19.2 GO:0015232 heme transporter activity(GO:0015232)
3.2 22.1 GO:0016401 palmitoyl-CoA oxidase activity(GO:0016401)
2.8 11.3 GO:0015226 amino-acid betaine transmembrane transporter activity(GO:0015199) carnitine transmembrane transporter activity(GO:0015226)
2.7 10.8 GO:0071614 linoleic acid epoxygenase activity(GO:0071614)
2.5 15.1 GO:0008745 N-acetylmuramoyl-L-alanine amidase activity(GO:0008745) peptidoglycan receptor activity(GO:0016019)
2.2 13.0 GO:0060230 lipoprotein lipase activator activity(GO:0060230)
2.0 24.5 GO:0036374 glutathione hydrolase activity(GO:0036374)
2.0 44.2 GO:0015125 bile acid transmembrane transporter activity(GO:0015125)
1.4 5.7 GO:0008109 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
1.4 4.2 GO:0034632 retinol transporter activity(GO:0034632)
1.1 6.6 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.9 4.7 GO:0003986 acetyl-CoA hydrolase activity(GO:0003986)
0.9 3.6 GO:0070653 high-density lipoprotein particle receptor binding(GO:0070653)
0.9 4.4 GO:0004998 transferrin receptor activity(GO:0004998)
0.9 9.6 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.8 3.2 GO:0003976 UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity(GO:0003976)
0.7 2.1 GO:0016297 [acyl-carrier-protein] S-malonyltransferase activity(GO:0004314) oleoyl-[acyl-carrier-protein] hydrolase activity(GO:0004320) myristoyl-[acyl-carrier-protein] hydrolase activity(GO:0016295) palmitoyl-[acyl-carrier-protein] hydrolase activity(GO:0016296) acyl-[acyl-carrier-protein] hydrolase activity(GO:0016297) S-acetyltransferase activity(GO:0016418) S-malonyltransferase activity(GO:0016419) malonyltransferase activity(GO:0016420) phosphopantetheine binding(GO:0031177)
0.6 2.6 GO:0047751 3-oxo-5-alpha-steroid 4-dehydrogenase activity(GO:0003865) cholestenone 5-alpha-reductase activity(GO:0047751)
0.6 1.9 GO:0038052 type 1 metabotropic glutamate receptor binding(GO:0031798) RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding(GO:0038052)
0.6 5.8 GO:0003909 DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910)
0.6 5.1 GO:0004630 phospholipase D activity(GO:0004630)
0.6 4.5 GO:0034235 GPI anchor binding(GO:0034235)
0.5 2.0 GO:0003960 NADPH:quinone reductase activity(GO:0003960)
0.5 15.0 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.4 11.2 GO:0019825 oxygen binding(GO:0019825)
0.4 1.1 GO:0046964 3'-phosphoadenosine 5'-phosphosulfate transmembrane transporter activity(GO:0046964)
0.4 12.3 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.3 1.1 GO:0008113 peptide-methionine (S)-S-oxide reductase activity(GO:0008113)
0.3 17.4 GO:0008395 steroid hydroxylase activity(GO:0008395)
0.3 6.3 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.2 2.2 GO:0034452 dynactin binding(GO:0034452)
0.2 0.7 GO:0032394 MHC class Ib receptor activity(GO:0032394)
0.2 1.6 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.2 7.4 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
0.2 18.1 GO:0017080 sodium channel regulator activity(GO:0017080)
0.2 4.4 GO:0035497 cAMP response element binding(GO:0035497)
0.2 4.6 GO:0004697 protein kinase C activity(GO:0004697)
0.2 1.2 GO:0046030 inositol-polyphosphate 5-phosphatase activity(GO:0004445) inositol trisphosphate phosphatase activity(GO:0046030)
0.2 3.1 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.2 1.6 GO:0098599 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.2 1.6 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.2 33.9 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.2 1.4 GO:0008481 sphinganine kinase activity(GO:0008481) D-erythro-sphingosine kinase activity(GO:0017050)
0.2 3.6 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.1 3.3 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.1 25.7 GO:0052689 carboxylic ester hydrolase activity(GO:0052689)
0.1 33.3 GO:0004866 endopeptidase inhibitor activity(GO:0004866)
0.1 1.3 GO:0004439 phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity(GO:0004439)
0.1 0.8 GO:0004311 farnesyltranstransferase activity(GO:0004311)
0.1 0.5 GO:0000309 nicotinamide-nucleotide adenylyltransferase activity(GO:0000309) nicotinate-nucleotide adenylyltransferase activity(GO:0004515)
0.1 0.6 GO:0004689 phosphorylase kinase activity(GO:0004689)
0.1 2.1 GO:0005212 structural constituent of eye lens(GO:0005212)
0.1 2.2 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.1 0.4 GO:0052834 inositol monophosphate 1-phosphatase activity(GO:0008934) inositol monophosphate 3-phosphatase activity(GO:0052832) inositol monophosphate 4-phosphatase activity(GO:0052833) inositol monophosphate phosphatase activity(GO:0052834)
0.1 7.2 GO:0005080 protein kinase C binding(GO:0005080)
0.1 1.6 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.1 1.8 GO:0015002 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.1 1.6 GO:0008137 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.1 2.0 GO:0019706 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.1 0.5 GO:0001640 adenylate cyclase inhibiting G-protein coupled glutamate receptor activity(GO:0001640)
0.0 0.7 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.0 5.5 GO:0003725 double-stranded RNA binding(GO:0003725)
0.0 1.3 GO:0031434 mitogen-activated protein kinase kinase binding(GO:0031434)
0.0 7.5 GO:0030165 PDZ domain binding(GO:0030165)
0.0 7.1 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
0.0 6.1 GO:0043130 ubiquitin binding(GO:0043130)
0.0 0.2 GO:0036313 phosphatidylinositol 3-kinase catalytic subunit binding(GO:0036313)
0.0 0.4 GO:0097322 7SK snRNA binding(GO:0097322)
0.0 0.8 GO:0030169 low-density lipoprotein particle binding(GO:0030169)
0.0 0.5 GO:0004017 adenylate kinase activity(GO:0004017)
0.0 0.2 GO:0015220 choline transmembrane transporter activity(GO:0015220)
0.0 1.6 GO:0016831 carboxy-lyase activity(GO:0016831)
0.0 0.3 GO:0005347 ATP transmembrane transporter activity(GO:0005347) ADP transmembrane transporter activity(GO:0015217)
0.0 2.2 GO:0004721 phosphoprotein phosphatase activity(GO:0004721)
0.0 0.9 GO:0051059 NF-kappaB binding(GO:0051059)
0.0 0.6 GO:0016881 acid-amino acid ligase activity(GO:0016881)
0.0 1.2 GO:0043022 ribosome binding(GO:0043022)
0.0 0.2 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.0 0.3 GO:0000030 mannosyltransferase activity(GO:0000030)
0.0 2.8 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 22.4 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.6 16.9 ST G ALPHA S PATHWAY G alpha s Pathway
0.2 38.0 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.2 12.4 PID AMB2 NEUTROPHILS PATHWAY amb2 Integrin signaling
0.2 1.6 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.1 5.1 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.1 15.7 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.1 1.6 ST GA12 PATHWAY G alpha 12 Pathway
0.0 2.2 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.0 1.4 PID S1P META PATHWAY Sphingosine 1-phosphate (S1P) pathway
0.0 1.9 PID ER NONGENOMIC PATHWAY Plasma membrane estrogen receptor signaling
0.0 2.1 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 1.2 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.0 1.3 ST ERK1 ERK2 MAPK PATHWAY ERK1/ERK2 MAPK Pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.8 25.1 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
1.4 15.0 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
1.2 13.9 REACTOME TRANSPORT OF ORGANIC ANIONS Genes involved in Transport of organic anions
0.9 22.1 REACTOME ALPHA LINOLENIC ACID ALA METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.8 11.2 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.6 16.6 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.5 6.2 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.5 6.4 REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.5 7.9 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.5 11.3 REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.4 7.4 REACTOME HS GAG DEGRADATION Genes involved in HS-GAG degradation
0.2 6.3 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.2 2.6 REACTOME ANDROGEN BIOSYNTHESIS Genes involved in Androgen biosynthesis
0.2 1.6 REACTOME OPSINS Genes involved in Opsins
0.2 1.6 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.2 15.9 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.1 3.1 REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.1 7.6 REACTOME PHASE1 FUNCTIONALIZATION OF COMPOUNDS Genes involved in Phase 1 - Functionalization of compounds
0.1 2.1 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.1 3.6 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.1 3.9 REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION Genes involved in Transport to the Golgi and subsequent modification
0.1 1.0 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.0 12.4 REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES Genes involved in Metabolism of amino acids and derivatives
0.0 0.8 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.0 2.8 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.0 1.0 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0 1.4 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.6 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.0 0.5 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.0 0.6 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.0 2.3 REACTOME RIG I MDA5 MEDIATED INDUCTION OF IFN ALPHA BETA PATHWAYS Genes involved in RIG-I/MDA5 mediated induction of IFN-alpha/beta pathways
0.0 0.6 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0 0.3 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0 0.4 REACTOME ELONGATION ARREST AND RECOVERY Genes involved in Elongation arrest and recovery
0.0 1.3 REACTOME PPARA ACTIVATES GENE EXPRESSION Genes involved in PPARA Activates Gene Expression