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GSE58827: Dynamics of the Mouse Liver

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Results for Nr2c1

Z-value: 0.75

Motif logo

Transcription factors associated with Nr2c1

Gene Symbol Gene ID Gene Info
ENSMUSG00000005897.15 nuclear receptor subfamily 2, group C, member 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Nr2c1mm39_v1_chr10_+_93983844_93983885-0.134.4e-01Click!

Activity profile of Nr2c1 motif

Sorted Z-values of Nr2c1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr15_+_79975520 3.91 ENSMUST00000009728.13
ENSMUST00000009727.12
synaptogyrin 1
chr7_+_30193047 2.93 ENSMUST00000058280.13
ENSMUST00000133318.8
ENSMUST00000142575.8
ENSMUST00000131040.2
proline dehydrogenase (oxidase) 2
chr8_-_124621483 2.84 ENSMUST00000034453.6
ENSMUST00000212584.2
actin, alpha 1, skeletal muscle
chr8_-_123187406 2.49 ENSMUST00000006762.7
snail family zinc finger 3
chrX_+_10351360 2.44 ENSMUST00000076354.13
ENSMUST00000115526.2
tetraspanin 7
chr1_-_59012579 2.29 ENSMUST00000173590.2
ENSMUST00000027186.12
trafficking protein, kinesin binding 2
chr11_+_4936824 2.21 ENSMUST00000109897.8
ENSMUST00000009234.16
adaptor protein complex AP-1, beta 1 subunit
chr7_+_110367375 2.04 ENSMUST00000170374.8
adenosine monophosphate deaminase 3
chr7_-_45570828 1.90 ENSMUST00000038876.13
epithelial membrane protein 3
chr5_+_145060489 1.86 ENSMUST00000136074.2
actin related protein 2/3 complex, subunit 1B
chr7_+_108533613 1.77 ENSMUST00000033342.7
eukaryotic translation initiation factor 3, subunit F
chr6_-_83030759 1.75 ENSMUST00000134606.8
HtrA serine peptidase 2
chr7_-_45570254 1.73 ENSMUST00000164119.3
epithelial membrane protein 3
chr10_-_93425553 1.72 ENSMUST00000020203.7
small nuclear ribonucleoprotein polypeptide F
chr7_-_45570538 1.70 ENSMUST00000210297.2
epithelial membrane protein 3
chr2_-_30720345 1.68 ENSMUST00000041726.4
ankyrin repeat and SOCS box-containing 6
chr7_-_45570674 1.53 ENSMUST00000210939.2
epithelial membrane protein 3
chr14_-_70414236 1.53 ENSMUST00000153735.8
PDZ and LIM domain 2
chr2_+_164647002 1.43 ENSMUST00000052107.5
zinc finger SWIM-type containing 3
chr11_-_3454766 1.37 ENSMUST00000044507.12
inositol polyphosphate 5-phosphatase J
chr17_+_35413415 1.35 ENSMUST00000025262.6
ENSMUST00000173600.2
lymphotoxin B
chr7_+_79836581 1.25 ENSMUST00000032754.9
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B
chr6_+_125122172 1.25 ENSMUST00000119527.8
ENSMUST00000117675.8
intermediate filament family orphan 1
chr3_+_96737385 1.22 ENSMUST00000058865.14
PDZ domain containing 1
chr2_+_22785534 1.21 ENSMUST00000053729.14
prenyl (solanesyl) diphosphate synthase, subunit 1
chr1_+_74545203 1.13 ENSMUST00000087215.7
CCR4-NOT transcription complex, subunit 9
chr9_-_106035332 1.10 ENSMUST00000112543.9
glycerate kinase
chr6_-_83031358 1.10 ENSMUST00000113962.8
ENSMUST00000089645.13
ENSMUST00000113963.8
HtrA serine peptidase 2
chr17_-_27816151 1.08 ENSMUST00000231742.2
nudix (nucleotide diphosphate linked moiety X)-type motif 3
chr13_+_73476629 1.07 ENSMUST00000221730.2
mitochondrial ribosomal protein L36
chrX_-_101232978 1.07 ENSMUST00000033683.8
ribosomal protein S4, X-linked
chr9_-_106035308 1.05 ENSMUST00000159809.2
ENSMUST00000162562.2
ENSMUST00000036382.13
glycerate kinase
chr4_-_41048124 1.05 ENSMUST00000030136.13
aquaporin 7
chr5_+_31454787 1.05 ENSMUST00000201166.4
ENSMUST00000072228.9
glucokinase regulatory protein
chr17_-_13211374 1.04 ENSMUST00000159551.8
ENSMUST00000160781.8
Wilms tumour 1-associating protein
chr7_-_19684654 1.02 ENSMUST00000043440.8
immunoglobulin superfamily, member 23
chr12_-_83534482 1.02 ENSMUST00000177959.8
ENSMUST00000178756.8
D4, zinc and double PHD fingers, family 3
chr4_+_131600918 1.02 ENSMUST00000053819.6
serine and arginine-rich splicing factor 4
chr5_+_135216090 1.01 ENSMUST00000002825.6
bromodomain adjacent to zinc finger domain, 1B
chr14_-_51162083 0.92 ENSMUST00000160375.8
ENSMUST00000162177.8
O-sialoglycoprotein endopeptidase
chr10_+_75152705 0.88 ENSMUST00000105420.3
adenosine A2a receptor
chr17_-_13211075 0.88 ENSMUST00000159986.8
ENSMUST00000007007.14
Wilms tumour 1-associating protein
chr5_+_137628377 0.83 ENSMUST00000175968.8
leucine-rich repeats and calponin homology (CH) domain containing 4
chr15_+_79025523 0.81 ENSMUST00000040077.8
polymerase (RNA) II (DNA directed) polypeptide F
chr13_-_41513215 0.80 ENSMUST00000224803.2
neural precursor cell expressed, developmentally down-regulated gene 9
chr7_-_28297565 0.77 ENSMUST00000040531.9
ENSMUST00000108283.8
sterile alpha motif domain containing 4B
p21 (RAC1) activated kinase 4
chr1_+_133237516 0.76 ENSMUST00000094557.7
ENSMUST00000192465.2
ENSMUST00000193888.6
ENSMUST00000194044.6
ENSMUST00000184603.8
golgi transport 1A
predicted gene, 28040
predicted gene, 28040
chr5_+_135717890 0.75 ENSMUST00000005651.13
ENSMUST00000122113.8
P450 (cytochrome) oxidoreductase
chr14_-_51162346 0.73 ENSMUST00000159292.8
O-sialoglycoprotein endopeptidase
chr4_-_130068484 0.73 ENSMUST00000132545.3
ENSMUST00000175992.8
ENSMUST00000105999.9
tubulointerstitial nephritis antigen-like 1
chr2_+_22785593 0.73 ENSMUST00000152170.8
prenyl (solanesyl) diphosphate synthase, subunit 1
chr15_-_102579463 0.70 ENSMUST00000185641.7
ATP synthase, H+ transporting, mitochondrial F0 complex, subunit C2 (subunit 9)
chr8_+_96551974 0.69 ENSMUST00000074053.6
Sin3-associated polypeptide 18B
chr13_+_55468313 0.69 ENSMUST00000021942.8
PRELI domain containing 1
chr11_+_83741689 0.69 ENSMUST00000108114.9
HNF1 homeobox B
chr15_+_101026803 0.67 ENSMUST00000119063.8
ENSMUST00000121718.8
activin A receptor, type II-like 1
chr11_+_83741657 0.65 ENSMUST00000021016.10
HNF1 homeobox B
chr17_+_7292967 0.64 ENSMUST00000097422.6
predicted gene 1604b
chr15_-_79025387 0.63 ENSMUST00000187550.7
ENSMUST00000188562.7
ENSMUST00000190509.7
ENSMUST00000190730.7
ENSMUST00000190959.7
ENSMUST00000169604.8
ENSMUST00000186053.7
RIKEN cDNA 1700088E04 gene
chr7_+_139673300 0.63 ENSMUST00000026540.9
proline-rich acidic protein 1
chr1_-_156767123 0.63 ENSMUST00000189316.7
ENSMUST00000190648.7
ENSMUST00000172057.8
ENSMUST00000191605.7
Ral GEF with PH domain and SH3 binding motif 2
chr3_-_8988854 0.62 ENSMUST00000042148.6
mitochondrial ribosomal protein S28
chr8_+_55024446 0.59 ENSMUST00000239166.2
ENSMUST00000239106.2
ENSMUST00000239152.2
ankyrin repeat and SOCs box-containing 5
chr19_-_45986919 0.56 ENSMUST00000045396.9
armadillo-like helical domain containing 3
chr3_+_58433236 0.56 ENSMUST00000029387.15
eukaryotic translation initiation factor 2A
chr11_-_63970270 0.55 ENSMUST00000049091.9
heme A:farnesyltransferase cytochrome c oxidase assembly factor 10
chr2_+_153187729 0.53 ENSMUST00000227428.2
ENSMUST00000109790.2
ASXL transcriptional regulator 1
chr10_-_14581203 0.53 ENSMUST00000149485.2
ENSMUST00000154132.8
vesicle (multivesicular body) trafficking 1
chr1_-_156766957 0.52 ENSMUST00000171292.8
ENSMUST00000063199.13
ENSMUST00000027886.14
Ral GEF with PH domain and SH3 binding motif 2
chr15_+_101026454 0.52 ENSMUST00000117984.8
activin A receptor, type II-like 1
chr10_-_119075910 0.50 ENSMUST00000020315.13
cullin associated and neddylation disassociated 1
chr5_-_137101108 0.50 ENSMUST00000077523.4
ENSMUST00000041388.11
serine (or cysteine) peptidase inhibitor, clade E, member 1
chr14_+_75373766 0.49 ENSMUST00000145303.8
lymphocyte cytosolic protein 1
chr11_-_115698894 0.48 ENSMUST00000132780.8
CASK-interacting protein 2
chr13_-_55718899 0.48 ENSMUST00000225240.3
ENSMUST00000021957.8
family with sequence similarity 193, member B
chr3_-_107538996 0.47 ENSMUST00000064759.7
striatin interacting protein 1
chr16_-_4340920 0.46 ENSMUST00000090500.10
ENSMUST00000023161.8
sarcalumenin
chr19_+_5012362 0.45 ENSMUST00000236917.2
mitochondrial ribosomal protein L11
chr7_-_28597523 0.44 ENSMUST00000216863.2
actinin alpha 4
chr14_+_58036071 0.44 ENSMUST00000111268.8
Sin3-associated polypeptide 18
chr2_+_109522781 0.44 ENSMUST00000111050.10
brain derived neurotrophic factor
chr9_+_118335294 0.43 ENSMUST00000084820.6
golgi autoantigen, golgin subfamily a, 4
chr2_+_158636727 0.43 ENSMUST00000029186.14
ENSMUST00000109478.9
ENSMUST00000156893.2
DEAH (Asp-Glu-Ala-His) box polypeptide 35
chr15_+_81695615 0.42 ENSMUST00000023024.8
thyrotroph embryonic factor
chr19_+_5012396 0.39 ENSMUST00000235229.2
mitochondrial ribosomal protein L11
chr3_-_94693780 0.38 ENSMUST00000107273.9
ENSMUST00000238849.2
cingulin
chr14_+_58035640 0.36 ENSMUST00000111269.2
Sin3-associated polypeptide 18
chr3_+_115681486 0.35 ENSMUST00000189799.7
ENSMUST00000200258.2
diphthamide biosynthesis 5
chr12_+_84034628 0.35 ENSMUST00000021649.8
acyl-CoA thioesterase 2
chr15_+_86098660 0.35 ENSMUST00000063414.9
TBC1 domain family, member 22a
chr17_+_75772475 0.35 ENSMUST00000095204.6
RAS, guanyl releasing protein 3
chr11_-_107228382 0.35 ENSMUST00000040380.13
phosphatidylinositol transfer protein, cytoplasmic 1
chr14_+_58036093 0.34 ENSMUST00000111267.2
Sin3-associated polypeptide 18
chr5_-_110927803 0.33 ENSMUST00000112426.8
pseudouridine synthase 1
chr1_-_74323795 0.33 ENSMUST00000178235.8
ENSMUST00000006462.14
angio-associated migratory protein
chr7_+_28580847 0.33 ENSMUST00000066880.6
calpain 12
chr14_-_52252003 0.31 ENSMUST00000226522.2
zinc finger protein 219
chr1_+_180553569 0.30 ENSMUST00000027780.6
acyl-Coenzyme A binding domain containing 3
chr17_+_57369231 0.29 ENSMUST00000097299.10
ENSMUST00000169543.8
ENSMUST00000163763.2
crumbs family member 3
chr11_-_100098333 0.29 ENSMUST00000007272.8
keratin 14
chr12_-_115083839 0.29 ENSMUST00000103521.3
immunoglobulin heavy variable 1-50
chr9_-_65298934 0.28 ENSMUST00000068307.4
kelch repeat and BTB (POZ) domain containing 13
chr19_+_5012336 0.28 ENSMUST00000237974.2
mitochondrial ribosomal protein L11
chr13_+_104424359 0.26 ENSMUST00000065766.7
a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 6
chr11_-_97657327 0.26 ENSMUST00000107579.2
ENSMUST00000018685.9
CWC25 spliceosome-associated protein
chr11_-_8574887 0.26 ENSMUST00000239091.2
tensin 3
chr1_-_74544946 0.25 ENSMUST00000044260.11
ENSMUST00000186282.7
ubiquitin specific peptidase 37
chr16_-_89940652 0.25 ENSMUST00000114124.9
T cell lymphoma invasion and metastasis 1
chr5_-_110928436 0.24 ENSMUST00000149208.2
ENSMUST00000031483.15
ENSMUST00000086643.12
ENSMUST00000170468.8
ENSMUST00000031481.13
pseudouridine synthase 1
chr16_-_32306683 0.23 ENSMUST00000042042.9
solute carrier family 51, alpha subunit
chr4_-_132459762 0.21 ENSMUST00000045550.5
X-linked Kx blood group related 8
chr1_-_74583434 0.19 ENSMUST00000189257.7
ubiquitin specific peptidase 37
chr5_-_137739863 0.19 ENSMUST00000061789.14
neuronal tyrosine-phosphorylated phosphoinositide 3-kinase adaptor 1
chr5_-_121974325 0.18 ENSMUST00000137682.2
SH2B adaptor protein 3
chr1_-_156767196 0.18 ENSMUST00000185198.7
Ral GEF with PH domain and SH3 binding motif 2
chr16_-_55659194 0.17 ENSMUST00000096026.9
ENSMUST00000036273.13
ENSMUST00000114457.8
nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, zeta
chr10_+_75152908 0.16 ENSMUST00000219044.2
adenosine A2a receptor
chr2_+_172994841 0.16 ENSMUST00000029017.6
phosphoenolpyruvate carboxykinase 1, cytosolic
chr4_+_156300325 0.14 ENSMUST00000105572.3
PPARGC1 and ESRR induced regulator, muscle 1
chr14_+_75373915 0.14 ENSMUST00000122840.8
lymphocyte cytosolic protein 1
chr11_+_98274637 0.14 ENSMUST00000008021.3
titin-cap
chr4_-_11076159 0.13 ENSMUST00000058183.9
NADH:ubiquinone oxidoreductase complex assembly factor 6
chr2_+_110427643 0.12 ENSMUST00000045972.13
ENSMUST00000111026.3
solute carrier family 5 (sodium/glucose cotransporter), member 12
chr10_+_4382467 0.12 ENSMUST00000095893.11
ENSMUST00000118544.8
ENSMUST00000117489.8
acidic residue methyltransferase 1
chr4_+_110254907 0.11 ENSMUST00000097920.9
ENSMUST00000080744.13
ATP/GTP binding protein-like 4
chr14_+_51162425 0.10 ENSMUST00000049411.12
ENSMUST00000136753.8
ENSMUST00000154288.3
apurinic/apyrimidinic endonuclease 1
chr9_-_60594742 0.10 ENSMUST00000114032.8
ENSMUST00000166168.8
ENSMUST00000132366.2
leucine rich repeat containing 49
chr1_+_59296065 0.10 ENSMUST00000160662.8
ENSMUST00000114248.3
cyclin-dependent kinase 15
chr7_+_82297803 0.09 ENSMUST00000141726.8
ENSMUST00000179489.8
ENSMUST00000039881.4
elongation factor like GTPase 1
chr17_+_38110779 0.09 ENSMUST00000215168.2
ENSMUST00000216478.2
olfactory receptor 124
chr13_-_93328719 0.08 ENSMUST00000048702.7
terminal nucleotidyltransferase 2
chr17_+_75772567 0.08 ENSMUST00000234660.2
RAS, guanyl releasing protein 3
chr2_-_62404195 0.08 ENSMUST00000174234.8
ENSMUST00000000402.16
ENSMUST00000174448.8
ENSMUST00000102732.10
fibroblast activation protein
chr17_-_26014613 0.08 ENSMUST00000235889.2
predicted gene, 50367
chr3_+_68479578 0.08 ENSMUST00000170788.9
schwannomin interacting protein 1
chr4_+_117109204 0.08 ENSMUST00000125943.8
ENSMUST00000106434.8
transmembrane protein 53
chr4_+_110254858 0.07 ENSMUST00000106589.9
ENSMUST00000106587.9
ENSMUST00000106591.8
ENSMUST00000106592.8
ATP/GTP binding protein-like 4
chr19_+_10914517 0.06 ENSMUST00000037261.4
prostaglandin D2 receptor 2
chr2_+_106525938 0.06 ENSMUST00000016530.14
metallophosphoesterase domain containing 2
chr13_-_93328883 0.06 ENSMUST00000225868.2
terminal nucleotidyltransferase 2
chr1_-_74323536 0.05 ENSMUST00000190008.2
angio-associated migratory protein
chr9_-_110818679 0.05 ENSMUST00000084922.6
ENSMUST00000199891.2
receptor transporter protein 3
chr4_-_120966396 0.04 ENSMUST00000106268.4
transmembrane and coiled-coil domains 2
chr3_+_103716836 0.04 ENSMUST00000076599.8
ENSMUST00000106824.8
ENSMUST00000106823.8
ENSMUST00000047285.7
adaptor-related protein complex AP-4, beta 1
chr15_-_76396151 0.03 ENSMUST00000023214.11
diacylglycerol O-acyltransferase 1
chr4_-_82939330 0.03 ENSMUST00000071708.12
Fras1 related extracellular matrix protein 1
chr14_+_58035614 0.03 ENSMUST00000128764.9
Sin3-associated polypeptide 18
chr19_+_5687503 0.03 ENSMUST00000025867.6
v-rel reticuloendotheliosis viral oncogene homolog A (avian)
chr17_-_52117894 0.03 ENSMUST00000176669.8
special AT-rich sequence binding protein 1
chr1_-_164285914 0.02 ENSMUST00000027863.13
ATPase, Na+/K+ transporting, beta 1 polypeptide
chr3_+_86131970 0.01 ENSMUST00000192145.6
ENSMUST00000194759.6
ENSMUST00000107635.7
LPS-responsive beige-like anchor
chr3_-_79535966 0.01 ENSMUST00000120992.8
electron transferring flavoprotein, dehydrogenase
chr14_-_52252432 0.00 ENSMUST00000226527.2
zinc finger protein 219
chr7_-_126483851 0.00 ENSMUST00000071268.11
ENSMUST00000117394.2
TAO kinase 2
chr17_+_35069347 0.00 ENSMUST00000097343.11
ENSMUST00000173357.8
ENSMUST00000173065.8
ENSMUST00000165953.3
negative elongation factor complex member E, Rdbp

Network of associatons between targets according to the STRING database.

First level regulatory network of Nr2c1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 2.9 GO:0010133 proline catabolic process to glutamate(GO:0010133)
0.9 2.8 GO:1904924 negative regulation of mitophagy in response to mitochondrial depolarization(GO:1904924)
0.4 1.7 GO:0002949 tRNA threonylcarbamoyladenosine modification(GO:0002949)
0.3 1.3 GO:0061235 regulation of pronephros size(GO:0035565) mesonephros morphogenesis(GO:0061206) mesonephric nephron development(GO:0061215) mesonephric nephron morphogenesis(GO:0061228) mesenchymal stem cell maintenance involved in mesonephric nephron morphogenesis(GO:0061235) regulation of mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis(GO:0061295) negative regulation of mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis(GO:0061296) mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis(GO:1901146)
0.3 3.0 GO:0030240 skeletal muscle thin filament assembly(GO:0030240)
0.3 1.1 GO:0071544 diphosphoinositol polyphosphate catabolic process(GO:0071544)
0.3 1.0 GO:0014057 positive regulation of acetylcholine secretion, neurotransmission(GO:0014057)
0.3 0.8 GO:0098749 cerebellar neuron development(GO:0098749)
0.2 2.3 GO:0098937 dendritic transport(GO:0098935) anterograde dendritic transport(GO:0098937)
0.2 6.9 GO:0032060 bleb assembly(GO:0032060)
0.2 1.1 GO:0070295 glycerol transport(GO:0015793) renal water absorption(GO:0070295)
0.2 2.0 GO:0032264 IMP salvage(GO:0032264)
0.2 0.8 GO:0043602 nitrate catabolic process(GO:0043602) nitric oxide catabolic process(GO:0046210) cellular organohalogen metabolic process(GO:0090345) cellular organofluorine metabolic process(GO:0090346)
0.2 1.1 GO:2000327 regulation of ligand-dependent nuclear receptor transcription coactivator activity(GO:2000325) positive regulation of ligand-dependent nuclear receptor transcription coactivator activity(GO:2000327)
0.2 4.3 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.2 0.5 GO:2000097 regulation of smooth muscle cell-matrix adhesion(GO:2000097)
0.2 1.4 GO:0045084 positive regulation of interleukin-12 biosynthetic process(GO:0045084)
0.1 1.0 GO:0009750 response to fructose(GO:0009750)
0.1 1.9 GO:0080009 mRNA methylation(GO:0080009)
0.1 1.2 GO:0015879 carnitine transport(GO:0015879)
0.1 0.5 GO:0035521 monoubiquitinated histone deubiquitination(GO:0035521) monoubiquitinated histone H2A deubiquitination(GO:0035522)
0.1 1.3 GO:0032485 regulation of Ral protein signal transduction(GO:0032485)
0.1 0.5 GO:0014873 response to muscle activity involved in regulation of muscle adaptation(GO:0014873)
0.1 0.6 GO:1990928 response to amino acid starvation(GO:1990928)
0.1 0.6 GO:0018343 protein farnesylation(GO:0018343)
0.1 0.4 GO:1902396 protein localization to bicellular tight junction(GO:1902396)
0.1 1.2 GO:0090500 lymphatic endothelial cell differentiation(GO:0060836) endocardial cushion to mesenchymal transition(GO:0090500)
0.1 0.6 GO:1990481 mRNA pseudouridine synthesis(GO:1990481)
0.1 0.3 GO:1904268 regulation of Schwann cell chemotaxis(GO:1904266) positive regulation of Schwann cell chemotaxis(GO:1904268) Schwann cell chemotaxis(GO:1990751)
0.1 1.9 GO:0006744 ubiquinone biosynthetic process(GO:0006744)
0.1 1.8 GO:0075522 IRES-dependent viral translational initiation(GO:0075522)
0.1 0.5 GO:0071985 multivesicular body sorting pathway(GO:0071985)
0.1 0.2 GO:0070782 phosphatidylserine exposure on apoptotic cell surface(GO:0070782)
0.1 0.4 GO:0017182 peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.1 2.2 GO:0048268 clathrin coat assembly(GO:0048268)
0.1 1.4 GO:0031115 negative regulation of microtubule polymerization(GO:0031115)
0.0 0.7 GO:1901857 negative regulation of mitochondrial membrane potential(GO:0010917) positive regulation of cellular respiration(GO:1901857)
0.0 0.8 GO:0045199 maintenance of epithelial cell apical/basal polarity(GO:0045199)
0.0 1.0 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.0 0.3 GO:0045110 intermediate filament bundle assembly(GO:0045110)
0.0 0.2 GO:0006114 glycerol biosynthetic process(GO:0006114) positive regulation of transcription from RNA polymerase II promoter in response to acidic pH(GO:0061402)
0.0 1.7 GO:0000387 spliceosomal snRNP assembly(GO:0000387)
0.0 1.9 GO:0034314 Arp2/3 complex-mediated actin nucleation(GO:0034314)
0.0 0.2 GO:0035609 C-terminal protein deglutamylation(GO:0035609)
0.0 0.4 GO:0042760 very long-chain fatty acid catabolic process(GO:0042760)
0.0 1.1 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.0 0.4 GO:0035871 protein K11-linked deubiquitination(GO:0035871)
0.0 0.6 GO:0071803 positive regulation of podosome assembly(GO:0071803)
0.0 0.1 GO:0010710 regulation of collagen catabolic process(GO:0010710) melanocyte proliferation(GO:0097325)
0.0 1.0 GO:0048025 negative regulation of mRNA splicing, via spliceosome(GO:0048025)
0.0 0.5 GO:0045899 positive regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045899)
0.0 0.7 GO:0015986 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.0 1.1 GO:0050919 negative chemotaxis(GO:0050919)
0.0 0.1 GO:0042256 mature ribosome assembly(GO:0042256)
0.0 0.0 GO:1901738 regulation of vitamin A metabolic process(GO:1901738)
0.0 0.1 GO:2000255 negative regulation of male germ cell proliferation(GO:2000255)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.9 GO:0036284 tubulobulbar complex(GO:0036284)
0.3 1.7 GO:0005683 U7 snRNP(GO:0005683)
0.3 1.9 GO:0036396 MIS complex(GO:0036396)
0.2 1.9 GO:0061574 ASAP complex(GO:0061574)
0.2 2.8 GO:0035631 CD40 receptor complex(GO:0035631)
0.2 1.7 GO:0000408 EKC/KEOPS complex(GO:0000408)
0.2 1.8 GO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
0.1 1.1 GO:0030015 CCR4-NOT core complex(GO:0030015)
0.1 0.5 GO:0042583 chromaffin granule(GO:0042583)
0.1 0.6 GO:0005850 eukaryotic translation initiation factor 2 complex(GO:0005850)
0.1 0.8 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.0 2.8 GO:0005865 striated muscle thin filament(GO:0005865)
0.0 1.0 GO:0032279 asymmetric synapse(GO:0032279)
0.0 2.2 GO:0030131 clathrin adaptor complex(GO:0030131)
0.0 0.7 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0 1.2 GO:0031528 microvillus membrane(GO:0031528)
0.0 3.3 GO:0099501 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.0 1.5 GO:0032839 dendrite cytoplasm(GO:0032839)
0.0 1.0 GO:0071565 nBAF complex(GO:0071565)
0.0 2.2 GO:0005762 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0 1.0 GO:0005721 pericentric heterochromatin(GO:0005721)
0.0 0.4 GO:0031143 pseudopodium(GO:0031143)
0.0 0.4 GO:0030061 mitochondrial crista(GO:0030061)
0.0 0.4 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.0 0.3 GO:0060091 kinocilium(GO:0060091)
0.0 0.6 GO:0001891 phagocytic cup(GO:0001891)
0.0 0.6 GO:0005763 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.0 1.1 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 1.5 GO:0005882 intermediate filament(GO:0005882)
0.0 1.4 GO:0043198 dendritic shaft(GO:0043198)
0.0 1.5 GO:0097517 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0 0.4 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.0 0.1 GO:0071438 invadopodium membrane(GO:0071438)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.7 GO:0061711 N(6)-L-threonylcarbamoyladenine synthase(GO:0061711)
0.5 1.9 GO:0050347 trans-hexaprenyltranstransferase activity(GO:0000010) trans-octaprenyltranstransferase activity(GO:0050347)
0.5 1.4 GO:0052658 inositol-1,4,5-trisphosphate 5-phosphatase activity(GO:0052658)
0.2 1.1 GO:0015254 glycerol channel activity(GO:0015254)
0.2 2.0 GO:0047623 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.2 0.8 GO:0008941 nitric oxide dioxygenase activity(GO:0008941) oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of two atoms of oxygen into one donor(GO:0016708) iron-cytochrome-c reductase activity(GO:0047726)
0.2 1.2 GO:0016361 activin receptor activity, type I(GO:0016361)
0.2 1.1 GO:0000298 endopolyphosphatase activity(GO:0000298) diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) bis(5'-adenosyl)-hexaphosphatase activity(GO:0034431) bis(5'-adenosyl)-pentaphosphatase activity(GO:0034432)
0.2 1.2 GO:0005124 scavenger receptor binding(GO:0005124)
0.1 0.4 GO:0005169 neurotrophin TRKB receptor binding(GO:0005169)
0.1 0.7 GO:1990050 phosphatidic acid transporter activity(GO:1990050)
0.1 1.0 GO:0070095 fructose-6-phosphate binding(GO:0070095)
0.1 1.0 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609)
0.1 1.5 GO:0032036 myosin heavy chain binding(GO:0032036)
0.1 2.9 GO:0071949 FAD binding(GO:0071949)
0.1 2.0 GO:0050811 GABA receptor binding(GO:0050811)
0.1 1.0 GO:1990825 sequence-specific mRNA binding(GO:1990825)
0.1 0.8 GO:0001055 RNA polymerase I activity(GO:0001054) RNA polymerase II activity(GO:0001055)
0.1 0.6 GO:0004311 farnesyltranstransferase activity(GO:0004311)
0.1 0.2 GO:0004611 phosphoenolpyruvate carboxykinase activity(GO:0004611) phosphoenolpyruvate carboxykinase (GTP) activity(GO:0004613)
0.0 0.3 GO:1990254 keratin filament binding(GO:1990254)
0.0 0.7 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.0 1.0 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.0 0.1 GO:0016890 site-specific endodeoxyribonuclease activity, specific for altered base(GO:0016890)
0.0 2.3 GO:0003743 translation initiation factor activity(GO:0003743)
0.0 0.6 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.0 0.8 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.0 0.3 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.0 0.1 GO:0051373 FATZ binding(GO:0051373)
0.0 1.4 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 2.2 GO:0019843 rRNA binding(GO:0019843)
0.0 0.7 GO:0030247 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.0 0.1 GO:0004958 prostaglandin F receptor activity(GO:0004958)
0.0 1.1 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 0.5 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.0 2.2 GO:0008565 protein transporter activity(GO:0008565)
0.0 0.5 GO:0017025 TBP-class protein binding(GO:0017025)
0.0 0.1 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.0 2.6 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 1.7 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 0.1 GO:0010340 carboxyl-O-methyltransferase activity(GO:0010340) protein carboxyl O-methyltransferase activity(GO:0051998)
0.0 0.3 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 0.2 GO:0016290 palmitoyl-CoA hydrolase activity(GO:0016290)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 2.8 PID RHOA PATHWAY RhoA signaling pathway
0.0 1.8 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.0 1.6 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 1.2 PID ALK1 PATHWAY ALK1 signaling events
0.0 1.9 PID RAC1 PATHWAY RAC1 signaling pathway
0.0 1.5 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 0.8 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.0 1.2 PID HEDGEHOG GLI PATHWAY Hedgehog signaling events mediated by Gli proteins
0.0 0.3 PID ARF6 DOWNSTREAM PATHWAY Arf6 downstream pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.2 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.1 1.7 REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.1 2.0 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.1 1.1 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.0 0.8 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.0 2.8 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0 1.0 REACTOME NUCLEOTIDE LIKE PURINERGIC RECEPTORS Genes involved in Nucleotide-like (purinergic) receptors
0.0 0.8 REACTOME RNA POL III CHAIN ELONGATION Genes involved in RNA Polymerase III Chain Elongation
0.0 1.0 REACTOME TRANSPORT OF MATURE TRANSCRIPT TO CYTOPLASM Genes involved in Transport of Mature Transcript to Cytoplasm
0.0 1.0 REACTOME REGULATION OF GLUCOKINASE BY GLUCOKINASE REGULATORY PROTEIN Genes involved in Regulation of Glucokinase by Glucokinase Regulatory Protein
0.0 1.3 REACTOME REGULATION OF BETA CELL DEVELOPMENT Genes involved in Regulation of beta-cell development
0.0 1.4 REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.0 0.4 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.0 0.4 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0 0.5 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0 0.5 REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.0 0.2 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism