ISMARA results: Nr2f1

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GSE58827: Dynamics of the Mouse Liver

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Results for Nr2f1_Nr4a1

Z-value: 1.90

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Transcription factors associated with Nr2f1_Nr4a1

Gene Symbol	Gene ID	Gene Info
Nr2f1 Ensembl NCBI MGI UniProt	ENSMUSG00000069171.15	nuclear receptor subfamily 2, group F, member 1
Nr4a1 Ensembl NCBI MGI UniProt	ENSMUSG00000023034.8	nuclear receptor subfamily 4, group A, member 1

Activity-expression correlation:

Gene	Promoter	Pearson corr. coef.	P-value	Plot
Nr2f1	mm39_v1_chr13_-_78344492_78344561	-0.18	3.1e-01	Click!
Nr4a1	mm39_v1_chr15_+_101152078_101152211	-0.02	9.1e-01	Click!

Activity profile of Nr2f1_Nr4a1 motif

Sorted Z-values of Nr2f1_Nr4a1 motif

Top targets:

Promoter	Log-likelihood	Transcript	Gene	Gene Info
chr9_-_46146558 Show fit	59.00	ENSMUST00000121916.8 ENSMUST00000034586.9	Apoc3 Ensembl NCBI MGI UniProt Show fit	apolipoprotein C-III
chr9_-_46146928 Show fit	43.96	ENSMUST00000118649.8	Apoc3 Ensembl NCBI MGI UniProt Show fit	apolipoprotein C-III
chr7_-_140856642 Show fit	35.00	ENSMUST00000080654.7 ENSMUST00000167263.9	Cdhr5 Ensembl NCBI MGI UniProt Show fit	cadherin-related family member 5
chr4_+_115375461 Show fit	32.41	ENSMUST00000058785.10 ENSMUST00000094886.4	Cyp4a10 Ensembl NCBI MGI UniProt Show fit	cytochrome P450, family 4, subfamily a, polypeptide 10
chr7_-_105249308 Show fit	24.30	ENSMUST00000210531.2 ENSMUST00000033185.10	Hpx Ensembl NCBI MGI UniProt Show fit	hemopexin
chr2_+_172994841 Show fit	23.39	ENSMUST00000029017.6	Pck1 Ensembl NCBI MGI UniProt Show fit	phosphoenolpyruvate carboxykinase 1, cytosolic
chr10_+_128030315 Show fit	19.35	ENSMUST00000044776.13	Gls2 Ensembl NCBI MGI UniProt Show fit	glutaminase 2 (liver, mitochondrial)
chr3_-_81883509 Show fit	17.79	ENSMUST00000029645.14 ENSMUST00000193879.2	Tdo2 Ensembl NCBI MGI UniProt Show fit	tryptophan 2,3-dioxygenase
chr19_-_43512929 Show fit	14.85	ENSMUST00000026196.14	Got1 Ensembl NCBI MGI UniProt Show fit	glutamic-oxaloacetic transaminase 1, soluble
chr6_+_90527762 Show fit	14.08	ENSMUST00000130418.8 ENSMUST00000032175.11 ENSMUST00000203111.2	Aldh1l1 Ensembl NCBI MGI UniProt Show fit	aldehyde dehydrogenase 1 family, member L1
chr10_+_128030500 Show fit	13.25	ENSMUST00000123291.2	Gls2 Ensembl NCBI MGI UniProt Show fit	glutaminase 2 (liver, mitochondrial)
chr4_+_134123631 Show fit	12.92	ENSMUST00000105869.9	Pafah2 Ensembl NCBI MGI UniProt Show fit	platelet-activating factor acetylhydrolase 2
chr11_+_115353290 Show fit	12.70	ENSMUST00000106532.4 ENSMUST00000092445.12 ENSMUST00000153466.2	Slc16a5 Ensembl NCBI MGI UniProt Show fit	solute carrier family 16 (monocarboxylic acid transporters), member 5
chr2_+_71811526 Show fit	12.55	ENSMUST00000090826.12 ENSMUST00000102698.10	Rapgef4 Ensembl NCBI MGI UniProt Show fit	Rap guanine nucleotide exchange factor (GEF) 4
chr4_-_62005498 Show fit	12.44	ENSMUST00000107488.4 ENSMUST00000107472.8 ENSMUST00000084531.11	Mup3 Ensembl NCBI MGI UniProt Show fit	major urinary protein 3
chr1_+_88093726 Show fit	12.18	ENSMUST00000097659.5	Ugt1a5 Ensembl NCBI MGI UniProt Show fit	UDP glucuronosyltransferase 1 family, polypeptide A5
chr11_-_116089595 Show fit	12.06	ENSMUST00000072948.11	Acox1 Ensembl NCBI MGI UniProt Show fit	acyl-Coenzyme A oxidase 1, palmitoyl
chr4_-_107164347 Show fit	12.03	ENSMUST00000082426.11	Dio1 Ensembl NCBI MGI UniProt Show fit	deiodinase, iodothyronine, type I
chr4_-_107164315 Show fit	11.19	ENSMUST00000126291.2 ENSMUST00000106748.2 ENSMUST00000129138.2	Dio1 Ensembl NCBI MGI UniProt Show fit	deiodinase, iodothyronine, type I
chr4_+_140688514 Show fit	11.08	ENSMUST00000010007.9	Sdhb Ensembl NCBI MGI UniProt Show fit	succinate dehydrogenase complex, subunit B, iron sulfur (Ip)
chr7_+_51537645 Show fit	10.90	ENSMUST00000208711.2	Gas2 Ensembl NCBI MGI UniProt Show fit	growth arrest specific 2
chr11_+_74540284 Show fit	10.35	ENSMUST00000117818.2 ENSMUST00000092915.12	Cluh Ensembl NCBI MGI UniProt Show fit	clustered mitochondria (cluA/CLU1) homolog
chr5_-_123320767 Show fit	10.30	ENSMUST00000154713.8 ENSMUST00000031398.14	Hpd Ensembl NCBI MGI UniProt Show fit	4-hydroxyphenylpyruvic acid dioxygenase
chr15_-_96947963 Show fit	10.24	ENSMUST00000230907.2	Slc38a4 Ensembl NCBI MGI UniProt Show fit	solute carrier family 38, member 4
chr11_+_75400889 Show fit	10.09	ENSMUST00000042972.7	Rilp Ensembl NCBI MGI UniProt Show fit	Rab interacting lysosomal protein
chr4_-_60457902 Show fit	10.00	ENSMUST00000084548.11 ENSMUST00000103012.10 ENSMUST00000107499.4	Mup1 Ensembl NCBI MGI UniProt Show fit	major urinary protein 1
chr17_-_46749370 Show fit	9.99	ENSMUST00000087012.7	Slc22a7 Ensembl NCBI MGI UniProt Show fit	solute carrier family 22 (organic anion transporter), member 7
chr17_-_56424265 Show fit	9.79	ENSMUST00000113072.3	Plin5 Ensembl NCBI MGI UniProt Show fit	perilipin 5
chr18_-_35760260 Show fit	9.69	ENSMUST00000025212.8	Slc23a1 Ensembl NCBI MGI UniProt Show fit	solute carrier family 23 (nucleobase transporters), member 1
chr17_-_56424577 Show fit	9.36	ENSMUST00000019808.12	Plin5 Ensembl NCBI MGI UniProt Show fit	perilipin 5
chrX_-_37545311 Show fit	9.20	ENSMUST00000074913.12 ENSMUST00000016678.14 ENSMUST00000061755.9	Lamp2 Ensembl NCBI MGI UniProt Show fit	lysosomal-associated membrane protein 2
chr3_-_137837117 Show fit	9.18	ENSMUST00000029805.13	Mttp Ensembl NCBI MGI UniProt Show fit	microsomal triglyceride transfer protein
chr3_-_20329823 Show fit	8.98	ENSMUST00000011607.6	Cpb1 Ensembl NCBI MGI UniProt Show fit	carboxypeptidase B1 (tissue)
chr2_+_58645189 Show fit	8.91	ENSMUST00000102755.4 ENSMUST00000230627.2 ENSMUST00000229923.2	Upp2 Ensembl NCBI MGI UniProt Show fit	uridine phosphorylase 2
chr9_+_46179899 Show fit	8.83	ENSMUST00000121598.8	Apoa5 Ensembl NCBI MGI UniProt Show fit	apolipoprotein A-V
chr1_-_139708906 Show fit	8.65	ENSMUST00000111986.8 ENSMUST00000027612.11 ENSMUST00000111989.9	Cfhr4 Ensembl NCBI MGI UniProt Show fit	complement factor H-related 4
chr9_+_46151994 Show fit	8.57	ENSMUST00000034585.7	Apoa4 Ensembl NCBI MGI UniProt Show fit	apolipoprotein A-IV
chr1_+_74324089 Show fit	8.47	ENSMUST00000113805.8 ENSMUST00000027370.13 ENSMUST00000087226.11	Pnkd Ensembl NCBI MGI UniProt Show fit	paroxysmal nonkinesiogenic dyskinesia
chr4_-_60777462 Show fit	8.47	ENSMUST00000211875.2	Mup22 Ensembl NCBI MGI UniProt Show fit	major urinary protein 22
chr10_-_78300802 Show fit	8.45	ENSMUST00000041616.15	Pdxk Ensembl NCBI MGI UniProt Show fit	pyridoxal (pyridoxine, vitamin B6) kinase
chr4_-_60697274 Show fit	8.40	ENSMUST00000117932.2	Mup12 Ensembl NCBI MGI UniProt Show fit	major urinary protein 12
chr19_+_46120327 Show fit	8.38	ENSMUST00000043739.6 ENSMUST00000237098.2	Elovl3 Ensembl NCBI MGI UniProt Show fit	elongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like 3
chr3_+_130411097 Show fit	8.35	ENSMUST00000166187.8 ENSMUST00000072271.13	Etnppl Ensembl NCBI MGI UniProt Show fit	ethanolamine phosphate phospholyase
chr9_-_107546195 Show fit	8.35	ENSMUST00000192990.6	Slc38a3 Ensembl NCBI MGI UniProt Show fit	solute carrier family 38, member 3
chr7_-_30755007 Show fit	8.35	ENSMUST00000206474.2 ENSMUST00000205807.2 ENSMUST00000039909.13 ENSMUST00000206305.2 ENSMUST00000205439.2	Fxyd1 Ensembl NCBI MGI UniProt Show fit	FXYD domain-containing ion transport regulator 1
chr8_+_70525546 Show fit	8.27	ENSMUST00000110160.9 ENSMUST00000049197.6	Tm6sf2 Ensembl NCBI MGI UniProt Show fit	transmembrane 6 superfamily member 2
chr1_-_139786421 Show fit	8.18	ENSMUST00000194186.6 ENSMUST00000094489.5 ENSMUST00000239380.2	Cfhr2 Ensembl NCBI MGI UniProt Show fit	complement factor H-related 2
chr7_-_30754223 Show fit	8.05	ENSMUST00000206012.2 ENSMUST00000108110.5	Fxyd1 Ensembl NCBI MGI UniProt Show fit	FXYD domain-containing ion transport regulator 1
chr1_-_139487951 Show fit	8.01	ENSMUST00000023965.8	Cfhr1 Ensembl NCBI MGI UniProt Show fit	complement factor H-related 1
chr13_-_41981812 Show fit	7.98	ENSMUST00000223337.2 ENSMUST00000221691.2	Adtrp Ensembl NCBI MGI UniProt Show fit	androgen dependent TFPI regulating protein
chr9_-_65330231 Show fit	7.96	ENSMUST00000065894.7	Slc51b Ensembl NCBI MGI UniProt Show fit	solute carrier family 51, beta subunit
chr9_-_107546166 Show fit	7.96	ENSMUST00000177567.8	Slc38a3 Ensembl NCBI MGI UniProt Show fit	solute carrier family 38, member 3
chr6_+_42222841 Show fit	7.96	ENSMUST00000031897.8	Gstk1 Ensembl NCBI MGI UniProt Show fit	glutathione S-transferase kappa 1
chr11_+_69945157 Show fit	7.77	ENSMUST00000108585.9 ENSMUST00000018699.13	Asgr1 Ensembl NCBI MGI UniProt Show fit	asialoglycoprotein receptor 1
chr2_-_91466739 Show fit	7.72	ENSMUST00000111335.2 ENSMUST00000028681.15	F2 Ensembl NCBI MGI UniProt Show fit	coagulation factor II
chr6_-_113508536 Show fit	7.68	ENSMUST00000032425.7	Emc3 Ensembl NCBI MGI UniProt Show fit	ER membrane protein complex subunit 3
chr7_-_30754193 Show fit	7.60	ENSMUST00000205778.2	Fxyd1 Ensembl NCBI MGI UniProt Show fit	FXYD domain-containing ion transport regulator 1
chr11_-_116089866 Show fit	7.59	ENSMUST00000066587.12	Acox1 Ensembl NCBI MGI UniProt Show fit	acyl-Coenzyme A oxidase 1, palmitoyl
chr1_-_140111138 Show fit	7.57	ENSMUST00000111976.9 ENSMUST00000066859.13	Cfh Ensembl NCBI MGI UniProt Show fit	complement component factor h
chr4_-_60222580 Show fit	7.44	ENSMUST00000095058.5 ENSMUST00000163931.8	Mup8 Ensembl NCBI MGI UniProt Show fit	major urinary protein 8
chr2_+_58644922 Show fit	7.42	ENSMUST00000059102.13	Upp2 Ensembl NCBI MGI UniProt Show fit	uridine phosphorylase 2
chr7_+_83281167 Show fit	7.30	ENSMUST00000075418.15	Stard5 Ensembl NCBI MGI UniProt Show fit	StAR-related lipid transfer (START) domain containing 5
chr1_-_140111018 Show fit	7.29	ENSMUST00000192880.6 ENSMUST00000111977.8	Cfh Ensembl NCBI MGI UniProt Show fit	complement component factor h
chr4_+_133280680 Show fit	7.20	ENSMUST00000042706.3	Nr0b2 Ensembl NCBI MGI UniProt Show fit	nuclear receptor subfamily 0, group B, member 2
chr6_+_138117519 Show fit	7.20	ENSMUST00000120939.8 ENSMUST00000204628.3 ENSMUST00000140932.2 ENSMUST00000120302.8	Mgst1 Ensembl NCBI MGI UniProt Show fit	microsomal glutathione S-transferase 1
chr9_+_107957621 Show fit	7.16	ENSMUST00000035211.14	Mst1 Ensembl NCBI MGI UniProt Show fit	macrophage stimulating 1 (hepatocyte growth factor-like)
chr5_-_87288177 Show fit	7.11	ENSMUST00000067790.7	Ugt2b5 Ensembl NCBI MGI UniProt Show fit	UDP glucuronosyltransferase 2 family, polypeptide B5
chr9_+_107957640 Show fit	7.00	ENSMUST00000162886.2	Mst1 Ensembl NCBI MGI UniProt Show fit	macrophage stimulating 1 (hepatocyte growth factor-like)
chrX_+_59044796 Show fit	6.89	ENSMUST00000033477.5	F9 Ensembl NCBI MGI UniProt Show fit	coagulation factor IX
chr13_-_74498320 Show fit	6.82	ENSMUST00000221594.2 ENSMUST00000022062.8	Sdha Ensembl NCBI MGI UniProt Show fit	succinate dehydrogenase complex, subunit A, flavoprotein (Fp)
chr17_-_35081456 Show fit	6.81	ENSMUST00000025229.11 ENSMUST00000176203.9 ENSMUST00000128767.8	Cfb Ensembl NCBI MGI UniProt Show fit	complement factor B
chr14_-_30637344 Show fit	6.77	ENSMUST00000226547.2	Itih3 Ensembl NCBI MGI UniProt Show fit	inter-alpha trypsin inhibitor, heavy chain 3
chr9_-_21900724 Show fit	6.71	ENSMUST00000045726.8	Rgl3 Ensembl NCBI MGI UniProt Show fit	ral guanine nucleotide dissociation stimulator-like 3
chr15_+_76579885 Show fit	6.68	ENSMUST00000231028.2	Gpt Ensembl NCBI MGI UniProt Show fit	glutamic pyruvic transaminase, soluble
chr11_-_53321606 Show fit	6.62	ENSMUST00000061326.5 ENSMUST00000109021.4	Uqcrq Ensembl NCBI MGI UniProt Show fit	ubiquinol-cytochrome c reductase, complex III subunit VII
chr14_+_79086665 Show fit	6.61	ENSMUST00000227255.2	Vwa8 Ensembl NCBI MGI UniProt Show fit	von Willebrand factor A domain containing 8
chr5_+_114284585 Show fit	6.55	ENSMUST00000102582.8	Acacb Ensembl NCBI MGI UniProt Show fit	acetyl-Coenzyme A carboxylase beta
chr7_+_140500808 Show fit	6.54	ENSMUST00000106045.8 ENSMUST00000183845.8	Nlrp6 Ensembl NCBI MGI UniProt Show fit	NLR family, pyrin domain containing 6
chr9_-_70841881 Show fit	6.46	ENSMUST00000214995.2	Lipc Ensembl NCBI MGI UniProt Show fit	lipase, hepatic
chr3_+_32791139 Show fit	6.44	ENSMUST00000127477.8 ENSMUST00000121778.8 ENSMUST00000154257.8	Ndufb5 Ensembl NCBI MGI UniProt Show fit	NADH:ubiquinone oxidoreductase subunit B5
chr14_-_20844074 Show fit	6.38	ENSMUST00000080440.14 ENSMUST00000100837.11 ENSMUST00000071816.7	Camk2g Ensembl NCBI MGI UniProt Show fit	calcium/calmodulin-dependent protein kinase II gamma
chr4_+_117109148 Show fit	6.35	ENSMUST00000062824.12	Tmem53 Ensembl NCBI MGI UniProt Show fit	transmembrane protein 53
chr3_+_130411294 Show fit	6.33	ENSMUST00000163620.8	Etnppl Ensembl NCBI MGI UniProt Show fit	ethanolamine phosphate phospholyase
chr15_+_7159038 Show fit	6.33	ENSMUST00000067190.12 ENSMUST00000164529.9	Lifr Ensembl NCBI MGI UniProt Show fit	LIF receptor alpha
chr7_-_30754240 Show fit	6.32	ENSMUST00000206860.2 ENSMUST00000071697.11	Fxyd1 Ensembl NCBI MGI UniProt Show fit	FXYD domain-containing ion transport regulator 1
chr4_+_117109204 Show fit	6.29	ENSMUST00000125943.8 ENSMUST00000106434.8	Tmem53 Ensembl NCBI MGI UniProt Show fit	transmembrane protein 53
chr1_-_192946359 Show fit	6.28	ENSMUST00000161737.8	Hsd11b1 Ensembl NCBI MGI UniProt Show fit	hydroxysteroid 11-beta dehydrogenase 1
chr8_+_95564949 Show fit	6.25	ENSMUST00000034234.15 ENSMUST00000159871.4	Coq9 Ensembl NCBI MGI UniProt Show fit	coenzyme Q9
chr17_-_35081129 Show fit	6.22	ENSMUST00000154526.8	Cfb Ensembl NCBI MGI UniProt Show fit	complement factor B
chr4_-_6275629 Show fit	6.22	ENSMUST00000029905.2	Cyp7a1 Ensembl NCBI MGI UniProt Show fit	cytochrome P450, family 7, subfamily a, polypeptide 1
chr6_+_145156860 Show fit	6.18	ENSMUST00000111725.8 ENSMUST00000111726.10 ENSMUST00000039729.5 ENSMUST00000111723.8 ENSMUST00000111724.8 ENSMUST00000111721.2 ENSMUST00000111719.2	Etfrf1 Ensembl NCBI MGI UniProt Show fit	electron transfer flavoprotein regulatory factor 1
chr1_-_130589349 Show fit	6.13	ENSMUST00000027657.14	C4bp Ensembl NCBI MGI UniProt Show fit	complement component 4 binding protein
chr1_-_130589321 Show fit	6.11	ENSMUST00000137276.3	C4bp Ensembl NCBI MGI UniProt Show fit	complement component 4 binding protein
chr2_-_28453374 Show fit	6.11	ENSMUST00000028161.6	Cel Ensembl NCBI MGI UniProt Show fit	carboxyl ester lipase
chr10_-_42354276 Show fit	6.08	ENSMUST00000151747.8	Afg1l Ensembl NCBI MGI UniProt Show fit	AFG1 like ATPase
chr14_+_79086492 Show fit	6.02	ENSMUST00000040990.7	Vwa8 Ensembl NCBI MGI UniProt Show fit	von Willebrand factor A domain containing 8
chr11_-_53313950 Show fit	5.97	ENSMUST00000036045.6	Leap2 Ensembl NCBI MGI UniProt Show fit	liver-expressed antimicrobial peptide 2
chr17_-_74257164 Show fit	5.95	ENSMUST00000024866.6	Xdh Ensembl NCBI MGI UniProt Show fit	xanthine dehydrogenase
chr4_+_128887017 Show fit	5.94	ENSMUST00000030583.13 ENSMUST00000102604.11	Ak2 Ensembl NCBI MGI UniProt Show fit	adenylate kinase 2
chr2_+_126398048 Show fit	5.93	ENSMUST00000141482.3	Slc27a2 Ensembl NCBI MGI UniProt Show fit	solute carrier family 27 (fatty acid transporter), member 2
chr1_+_166081664 Show fit	5.87	ENSMUST00000111416.7	Ildr2 Ensembl NCBI MGI UniProt Show fit	immunoglobulin-like domain containing receptor 2
chr19_+_3372296 Show fit	5.84	ENSMUST00000237938.2	Cpt1a Ensembl NCBI MGI UniProt Show fit	carnitine palmitoyltransferase 1a, liver
chr2_-_157408239 Show fit	5.80	ENSMUST00000109528.9 ENSMUST00000088494.3	Blcap Ensembl NCBI MGI UniProt Show fit	bladder cancer associated protein
chr7_+_140500848 Show fit	5.69	ENSMUST00000184560.2	Nlrp6 Ensembl NCBI MGI UniProt Show fit	NLR family, pyrin domain containing 6
chr6_+_91134358 Show fit	5.68	ENSMUST00000155007.2	Hdac11 Ensembl NCBI MGI UniProt Show fit	histone deacetylase 11
chr2_-_134396268 Show fit	5.65	ENSMUST00000028704.3	Hao1 Ensembl NCBI MGI UniProt Show fit	hydroxyacid oxidase 1, liver
chr3_+_118355778 Show fit	5.64	ENSMUST00000039177.12	Dpyd Ensembl NCBI MGI UniProt Show fit	dihydropyrimidine dehydrogenase
chr3_-_79535966 Show fit	5.64	ENSMUST00000120992.8	Etfdh Ensembl NCBI MGI UniProt Show fit	electron transferring flavoprotein, dehydrogenase
chr2_-_25390625 Show fit	5.56	ENSMUST00000040042.11	C8g Ensembl NCBI MGI UniProt Show fit	complement component 8, gamma polypeptide
chr10_+_79552421 Show fit	5.56	ENSMUST00000099513.8 ENSMUST00000020581.3	Hcn2 Ensembl NCBI MGI UniProt Show fit	hyperpolarization-activated, cyclic nucleotide-gated K+ 2
chr8_-_13544478 Show fit	5.41	ENSMUST00000033828.7	Gas6 Ensembl NCBI MGI UniProt Show fit	growth arrest specific 6
chr14_+_75479727 Show fit	5.37	ENSMUST00000022576.10	Cpb2 Ensembl NCBI MGI UniProt Show fit	carboxypeptidase B2 (plasma)
chr2_-_136733282 Show fit	5.35	ENSMUST00000028730.13 ENSMUST00000110089.9 ENSMUST00000227806.2	Mkks Ensembl NCBI MGI UniProt Show fit ENSMUSG00000115423.3 Ensembl NCBI MGI UniProt Show fit	McKusick-Kaufman syndrome novel protein
chr1_+_131725119 Show fit	5.34	ENSMUST00000112393.9 ENSMUST00000048660.12	Pm20d1 Ensembl NCBI MGI UniProt Show fit	peptidase M20 domain containing 1
chr14_+_55813074 Show fit	5.22	ENSMUST00000022826.7	Fitm1 Ensembl NCBI MGI UniProt Show fit	fat storage-inducing transmembrane protein 1
chr10_-_42354482 Show fit	5.21	ENSMUST00000041024.15	Afg1l Ensembl NCBI MGI UniProt Show fit	AFG1 like ATPase
chr11_-_11848107 Show fit	5.20	ENSMUST00000178704.8	Ddc Ensembl NCBI MGI UniProt Show fit	dopa decarboxylase
chr17_-_26087696 Show fit	5.16	ENSMUST00000236479.2 ENSMUST00000235806.2 ENSMUST00000026828.7	Mcrip2 Ensembl NCBI MGI UniProt Show fit	MAPK regulated corepressor interacting protein 2
chr4_-_129121676 Show fit	4.99	ENSMUST00000106051.8	C77080 Ensembl NCBI MGI UniProt Show fit	expressed sequence C77080
chr2_-_69172944 Show fit	4.98	ENSMUST00000102709.8 ENSMUST00000102710.10 ENSMUST00000180142.2	Abcb11 Ensembl NCBI MGI UniProt Show fit	ATP-binding cassette, sub-family B (MDR/TAP), member 11
chr7_+_44114815 Show fit	4.86	ENSMUST00000035929.11 ENSMUST00000146128.8	Aspdh Ensembl NCBI MGI UniProt Show fit	aspartate dehydrogenase domain containing
chr8_+_121395047 Show fit	4.84	ENSMUST00000181795.2	Cox4i1 Ensembl NCBI MGI UniProt Show fit	cytochrome c oxidase subunit 4I1
chr1_+_4878046 Show fit	4.81	ENSMUST00000027036.11 ENSMUST00000150971.8 ENSMUST00000119612.9 ENSMUST00000137887.8 ENSMUST00000115529.8	Lypla1 Ensembl NCBI MGI UniProt Show fit	lysophospholipase 1
chr9_-_21913833 Show fit	4.78	ENSMUST00000115336.10	Odad3 Ensembl NCBI MGI UniProt Show fit	outer dynein arm docking complex subunit 3
chr5_-_147259245 Show fit	4.78	ENSMUST00000100433.5	Urad Ensembl NCBI MGI UniProt Show fit	ureidoimidazoline (2-oxo-4-hydroxy-4-carboxy-5) decarboxylase
chr11_-_11848044 Show fit	4.77	ENSMUST00000066237.10	Ddc Ensembl NCBI MGI UniProt Show fit	dopa decarboxylase
chr9_-_70048766 Show fit	4.74	ENSMUST00000034749.16	Fam81a Ensembl NCBI MGI UniProt Show fit	family with sequence similarity 81, member A
chr1_+_67162176 Show fit	4.72	ENSMUST00000027144.8	Cps1 Ensembl NCBI MGI UniProt Show fit	carbamoyl-phosphate synthetase 1
chr6_+_91133647 Show fit	4.72	ENSMUST00000041736.11	Hdac11 Ensembl NCBI MGI UniProt Show fit	histone deacetylase 11
chr12_+_41074328 Show fit	4.71	ENSMUST00000134965.8	Immp2l Ensembl NCBI MGI UniProt Show fit	IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae)
chr2_+_92205651 Show fit	4.71	ENSMUST00000028650.9	Pex16 Ensembl NCBI MGI UniProt Show fit	peroxisomal biogenesis factor 16
chr18_+_45402018 Show fit	4.68	ENSMUST00000183850.8 ENSMUST00000066890.14	Kcnn2 Ensembl NCBI MGI UniProt Show fit	potassium intermediate/small conductance calcium-activated channel, subfamily N, member 2
chr1_+_139429430 Show fit	4.63	ENSMUST00000027615.7	F13b Ensembl NCBI MGI UniProt Show fit	coagulation factor XIII, beta subunit
chr7_+_44114857 Show fit	4.63	ENSMUST00000135624.2	Aspdh Ensembl NCBI MGI UniProt Show fit	aspartate dehydrogenase domain containing
chr5_-_108822619 Show fit	4.61	ENSMUST00000119270.2 ENSMUST00000163328.8 ENSMUST00000136227.2	Slc26a1 Ensembl NCBI MGI UniProt Show fit	solute carrier family 26 (sulfate transporter), member 1
chr10_+_110756031 Show fit	4.60	ENSMUST00000220409.2 ENSMUST00000219502.2	Csrp2 Ensembl NCBI MGI UniProt Show fit	cysteine and glycine-rich protein 2
chr8_-_85500010 Show fit	4.60	ENSMUST00000109764.8	Nfix Ensembl NCBI MGI UniProt Show fit	nuclear factor I/X
chr16_-_56984137 Show fit	4.57	ENSMUST00000231733.2	Nit2 Ensembl NCBI MGI UniProt Show fit	nitrilase family, member 2
chr14_-_20844034 Show fit	4.55	ENSMUST00000226630.2	Camk2g Ensembl NCBI MGI UniProt Show fit	calcium/calmodulin-dependent protein kinase II gamma
chr7_+_127399776 Show fit	4.52	ENSMUST00000046863.12 ENSMUST00000206674.2 ENSMUST00000106272.8	Hsd3b7 Ensembl NCBI MGI UniProt Show fit	hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7
chr17_+_15163466 Show fit	4.51	ENSMUST00000164837.3 ENSMUST00000174004.2	1600012H06Rik Ensembl NCBI MGI UniProt Show fit	RIKEN cDNA 1600012H06 gene
chr19_+_37686240 Show fit	4.50	ENSMUST00000025946.7	Cyp26a1 Ensembl NCBI MGI UniProt Show fit	cytochrome P450, family 26, subfamily a, polypeptide 1
chr16_-_20549294 Show fit	4.50	ENSMUST00000231826.2 ENSMUST00000076422.13 ENSMUST00000232217.2	Thpo Ensembl NCBI MGI UniProt Show fit	thrombopoietin
chr1_-_164285914 Show fit	4.49	ENSMUST00000027863.13	Atp1b1 Ensembl NCBI MGI UniProt Show fit	ATPase, Na+/K+ transporting, beta 1 polypeptide
chr11_-_46581135 Show fit	4.36	ENSMUST00000169584.8	Timd2 Ensembl NCBI MGI UniProt Show fit	T cell immunoglobulin and mucin domain containing 2
chr7_-_126944754 Show fit	4.33	ENSMUST00000205266.2	Zfp768 Ensembl NCBI MGI UniProt Show fit	zinc finger protein 768
chr4_-_141351110 Show fit	4.33	ENSMUST00000038661.8	Slc25a34 Ensembl NCBI MGI UniProt Show fit	solute carrier family 25, member 34
chr3_+_122688721 Show fit	4.33	ENSMUST00000023820.6	Fabp2 Ensembl NCBI MGI UniProt Show fit	fatty acid binding protein 2, intestinal
chr14_-_47426863 Show fit	4.30	ENSMUST00000089959.7	Gch1 Ensembl NCBI MGI UniProt Show fit	GTP cyclohydrolase 1
chr13_+_51254852 Show fit	4.30	ENSMUST00000095797.6	Spin1 Ensembl NCBI MGI UniProt Show fit	spindlin 1
chr6_-_124519240 Show fit	4.28	ENSMUST00000159463.8 ENSMUST00000162844.2 ENSMUST00000160505.8 ENSMUST00000162443.8	C1s1 Ensembl NCBI MGI UniProt Show fit	complement component 1, s subcomponent 1
chr7_+_127399789 Show fit	4.24	ENSMUST00000125188.8	Hsd3b7 Ensembl NCBI MGI UniProt Show fit	hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7
chr4_+_115420817 Show fit	4.22	ENSMUST00000141033.8 ENSMUST00000030486.15	Cyp4a31 Ensembl NCBI MGI UniProt Show fit	cytochrome P450, family 4, subfamily a, polypeptide 31
chr4_+_155646807 Show fit	4.22	ENSMUST00000030939.14	Nadk Ensembl NCBI MGI UniProt Show fit	NAD kinase
chr9_-_70842090 Show fit	4.21	ENSMUST00000034731.10	Lipc Ensembl NCBI MGI UniProt Show fit	lipase, hepatic
chr8_+_120121612 Show fit	4.18	ENSMUST00000098367.5	Mlycd Ensembl NCBI MGI UniProt Show fit	malonyl-CoA decarboxylase
chr15_+_76227695 Show fit	4.17	ENSMUST00000023210.8 ENSMUST00000231045.2	Cyc1 Ensembl NCBI MGI UniProt Show fit	cytochrome c-1
chr9_-_21913896 Show fit	4.16	ENSMUST00000044926.6	Odad3 Ensembl NCBI MGI UniProt Show fit	outer dynein arm docking complex subunit 3
chr4_+_115420876 Show fit	4.15	ENSMUST00000126645.8 ENSMUST00000030480.4	Cyp4a31 Ensembl NCBI MGI UniProt Show fit	cytochrome P450, family 4, subfamily a, polypeptide 31
chr6_+_41279199 Show fit	4.13	ENSMUST00000031913.5	Try4 Ensembl NCBI MGI UniProt Show fit	trypsin 4
chr5_-_25200745 Show fit	4.12	ENSMUST00000076306.12	Prkag2 Ensembl NCBI MGI UniProt Show fit	protein kinase, AMP-activated, gamma 2 non-catalytic subunit
chr9_-_21996693 Show fit	4.09	ENSMUST00000179422.8 ENSMUST00000098937.10 ENSMUST00000177967.2 ENSMUST00000180180.8	Ecsit Ensembl NCBI MGI UniProt Show fit	ECSIT signalling integrator
chr17_-_32639936 Show fit	4.08	ENSMUST00000170392.9 ENSMUST00000237165.2 ENSMUST00000235892.2 ENSMUST00000114455.3	Pglyrp2 Ensembl NCBI MGI UniProt Show fit	peptidoglycan recognition protein 2
chr11_+_75358866 Show fit	4.08	ENSMUST00000043598.14 ENSMUST00000108435.2	Tlcd2 Ensembl NCBI MGI UniProt Show fit	TLC domain containing 2
chr4_+_134124691 Show fit	4.06	ENSMUST00000105870.8	Pafah2 Ensembl NCBI MGI UniProt Show fit	platelet-activating factor acetylhydrolase 2
chr6_+_91133755 Show fit	4.04	ENSMUST00000143621.8	Hdac11 Ensembl NCBI MGI UniProt Show fit	histone deacetylase 11
chr4_+_141473983 Show fit	4.00	ENSMUST00000038161.5	Agmat Ensembl NCBI MGI UniProt Show fit	agmatine ureohydrolase (agmatinase)
chr7_+_45546365 Show fit	3.98	ENSMUST00000069772.16 ENSMUST00000210503.2 ENSMUST00000209350.2	Tmem143 Ensembl NCBI MGI UniProt Show fit	transmembrane protein 143
chr7_+_83281193 Show fit	3.96	ENSMUST00000117410.2	Stard5 Ensembl NCBI MGI UniProt Show fit	StAR-related lipid transfer (START) domain containing 5
chr19_+_43770619 Show fit	3.92	ENSMUST00000026208.6	Abcc2 Ensembl NCBI MGI UniProt Show fit	ATP-binding cassette, sub-family C (CFTR/MRP), member 2
chr8_-_122379631 Show fit	3.90	ENSMUST00000046386.5	Zcchc14 Ensembl NCBI MGI UniProt Show fit	zinc finger, CCHC domain containing 14
chr9_+_21914083 Show fit	3.86	ENSMUST00000216344.2	Prkcsh Ensembl NCBI MGI UniProt Show fit	protein kinase C substrate 80K-H
chr9_+_107217786 Show fit	3.82	ENSMUST00000042581.4	6430571L13Rik Ensembl NCBI MGI UniProt Show fit	RIKEN cDNA 6430571L13 gene
chr16_+_23338960 Show fit	3.78	ENSMUST00000211460.2 ENSMUST00000210658.2 ENSMUST00000209198.2 ENSMUST00000210371.2 ENSMUST00000211499.2 ENSMUST00000210795.2 ENSMUST00000209422.2	Gm45338 Ensembl NCBI MGI UniProt Show fit Rtp4 Ensembl NCBI MGI UniProt Show fit	predicted gene 45338 receptor transporter protein 4
chr1_-_134163102 Show fit	3.78	ENSMUST00000187631.2 ENSMUST00000038191.8 ENSMUST00000086465.6	Adora1 Ensembl NCBI MGI UniProt Show fit	adenosine A1 receptor
chr19_-_4548602 Show fit	3.76	ENSMUST00000048482.8	2010003K11Rik Ensembl NCBI MGI UniProt Show fit	RIKEN cDNA 2010003K11 gene
chr5_+_115604321 Show fit	3.70	ENSMUST00000145785.8 ENSMUST00000031495.11 ENSMUST00000112071.8 ENSMUST00000125568.2	Pla2g1b Ensembl NCBI MGI UniProt Show fit	phospholipase A2, group IB, pancreas
chr16_+_17149235 Show fit	3.63	ENSMUST00000023450.15 ENSMUST00000231884.2	Serpind1 Ensembl NCBI MGI UniProt Show fit	serine (or cysteine) peptidase inhibitor, clade D, member 1
chr17_+_85335775 Show fit	3.63	ENSMUST00000024944.9	Slc3a1 Ensembl NCBI MGI UniProt Show fit	solute carrier family 3, member 1
chr18_-_62044871 Show fit	3.62	ENSMUST00000166783.3 ENSMUST00000049378.15	Ablim3 Ensembl NCBI MGI UniProt Show fit	actin binding LIM protein family, member 3
chr16_+_10363222 Show fit	3.61	ENSMUST00000155633.8 ENSMUST00000066345.15	Clec16a Ensembl NCBI MGI UniProt Show fit	C-type lectin domain family 16, member A
chr19_-_39451509 Show fit	3.61	ENSMUST00000035488.3	Cyp2c38 Ensembl NCBI MGI UniProt Show fit	cytochrome P450, family 2, subfamily c, polypeptide 38
chr15_+_25843225 Show fit	3.61	ENSMUST00000022881.15	Retreg1 Ensembl NCBI MGI UniProt Show fit	reticulophagy regulator 1
chr11_+_100973391 Show fit	3.60	ENSMUST00000001806.10 ENSMUST00000107308.4	Coasy Ensembl NCBI MGI UniProt Show fit	Coenzyme A synthase
chr11_-_113600346 Show fit	3.58	ENSMUST00000173655.8 ENSMUST00000100248.6	Cpsf4l Ensembl NCBI MGI UniProt Show fit	cleavage and polyadenylation specific factor 4-like
chr7_-_126496534 Show fit	3.58	ENSMUST00000120007.8	Tmem219 Ensembl NCBI MGI UniProt Show fit	transmembrane protein 219
chr7_-_79492091 Show fit	3.58	ENSMUST00000049004.8	Anpep Ensembl NCBI MGI UniProt Show fit	alanyl (membrane) aminopeptidase
chr4_-_115932219 Show fit	3.56	ENSMUST00000050580.11 ENSMUST00000078676.6	Uqcrh Ensembl NCBI MGI UniProt Show fit	ubiquinol-cytochrome c reductase hinge protein
chr2_-_26494277 Show fit	3.56	ENSMUST00000028286.12	Agpat2 Ensembl NCBI MGI UniProt Show fit	1-acylglycerol-3-phosphate O-acyltransferase 2 (lysophosphatidic acid acyltransferase, beta)
chr1_-_120001752 Show fit	3.55	ENSMUST00000056089.8	Tmem37 Ensembl NCBI MGI UniProt Show fit	transmembrane protein 37
chr3_+_122298308 Show fit	3.53	ENSMUST00000199358.2	Bcar3 Ensembl NCBI MGI UniProt Show fit	breast cancer anti-estrogen resistance 3
chr4_+_138694422 Show fit	3.51	ENSMUST00000116094.5 ENSMUST00000239443.2	Rnf186 Ensembl NCBI MGI UniProt Show fit	ring finger protein 186
chr13_-_64514830 Show fit	3.48	ENSMUST00000222971.2	Ctsl Ensembl NCBI MGI UniProt Show fit	cathepsin L
chr17_-_34247016 Show fit	3.45	ENSMUST00000236627.2 ENSMUST00000237759.2 ENSMUST00000045467.14 ENSMUST00000114303.4	H2-Ke6 Ensembl NCBI MGI UniProt Show fit	H2-K region expressed gene 6
chr3_+_62245765 Show fit	3.45	ENSMUST00000079300.13	Arhgef26 Ensembl NCBI MGI UniProt Show fit	Rho guanine nucleotide exchange factor (GEF) 26
chr6_-_119444157 Show fit	3.44	ENSMUST00000118120.8	Wnt5b Ensembl NCBI MGI UniProt Show fit	wingless-type MMTV integration site family, member 5B
chr1_+_167445815 Show fit	3.44	ENSMUST00000111380.2	Rxrg Ensembl NCBI MGI UniProt Show fit	retinoid X receptor gamma
chr9_-_110571645 Show fit	3.41	ENSMUST00000006005.12	Pth1r Ensembl NCBI MGI UniProt Show fit	parathyroid hormone 1 receptor
chr2_-_160714749 Show fit	3.39	ENSMUST00000176141.8	Zhx3 Ensembl NCBI MGI UniProt Show fit	zinc fingers and homeoboxes 3
chr6_-_119521243 Show fit	3.38	ENSMUST00000119369.2 ENSMUST00000178696.8	Wnt5b Ensembl NCBI MGI UniProt Show fit	wingless-type MMTV integration site family, member 5B

Network of associatons between targets according to the STRING database.

First level regulatory network of Nr2f1_Nr4a1

View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
25.7	103.0	GO:0010982	regulation of high-density lipoprotein particle clearance(GO:0010982)
9.9	39.7	GO:0061402	positive regulation of transcription from RNA polymerase II promoter in response to acidic pH(GO:0061402)
6.8	34.2	GO:1904970	brush border assembly(GO:1904970)
5.9	17.8	GO:0006106	fumarate metabolic process(GO:0006106)
5.9	17.8	GO:0019442	tryptophan catabolic process to acetyl-CoA(GO:0019442)
5.0	29.9	GO:0006543	glutamine catabolic process(GO:0006543)
4.7	14.1	GO:0009397	10-formyltetrahydrofolate catabolic process(GO:0009258) folic acid-containing compound catabolic process(GO:0009397) pteridine-containing compound catabolic process(GO:0042560)
4.1	12.3	GO:0044240	multicellular organism lipid catabolic process(GO:0044240)
3.9	3.9	GO:0050787	detoxification of mercury ion(GO:0050787)
3.8	19.1	GO:0035359	negative regulation of triglyceride catabolic process(GO:0010897) negative regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035359)
3.6	10.7	GO:2001293	malonyl-CoA metabolic process(GO:2001293)
3.5	24.3	GO:0060335	positive regulation of humoral immune response mediated by circulating immunoglobulin(GO:0002925) heme transport(GO:0015886) positive regulation of response to interferon-gamma(GO:0060332) positive regulation of interferon-gamma-mediated signaling pathway(GO:0060335)
3.4	37.2	GO:1903275	positive regulation of sodium ion export(GO:1903275) positive regulation of sodium ion export from cell(GO:1903278)
3.4	10.1	GO:0070676	intralumenal vesicle formation(GO:0070676)
3.4	10.1	GO:1904766	negative regulation of macroautophagy by TORC1 signaling(GO:1904766)
3.3	19.7	GO:0033540	fatty acid beta-oxidation using acyl-CoA oxidase(GO:0033540)
3.2	9.7	GO:0070904	L-ascorbic acid transport(GO:0015882) transepithelial L-ascorbic acid transport(GO:0070904)
3.1	9.2	GO:0071211	protein targeting to vacuole involved in autophagy(GO:0071211)
3.0	8.9	GO:0019860	uracil catabolic process(GO:0006212) uracil metabolic process(GO:0019860)
2.9	22.9	GO:0045919	positive regulation of cytolysis(GO:0045919)
2.8	8.5	GO:0042822	pyridoxal phosphate metabolic process(GO:0042822)
2.5	12.6	GO:1904457	positive regulation of neuronal action potential(GO:1904457)
2.4	4.8	GO:0000255	allantoin metabolic process(GO:0000255)
2.3	9.2	GO:0034197	acylglycerol transport(GO:0034196) triglyceride transport(GO:0034197)
2.2	8.8	GO:0010901	regulation of very-low-density lipoprotein particle remodeling(GO:0010901)
2.1	10.7	GO:0034371	chylomicron remodeling(GO:0034371)
2.1	6.3	GO:0006713	glucocorticoid catabolic process(GO:0006713)
2.0	5.9	GO:0097089	methyl-branched fatty acid metabolic process(GO:0097089)
1.9	11.3	GO:0035694	mitochondrial protein catabolic process(GO:0035694)
1.8	5.4	GO:2000275	regulation of oxidative phosphorylation uncoupler activity(GO:2000275)
1.8	7.2	GO:0071449	cellular response to lipid hydroperoxide(GO:0071449)
1.8	5.4	GO:0003330	regulation of extracellular matrix constituent secretion(GO:0003330) positive regulation of extracellular matrix constituent secretion(GO:0003331)
1.7	8.4	GO:0006121	mitochondrial electron transport, succinate to ubiquinone(GO:0006121)
1.6	8.0	GO:0051715	cytolysis in other organism(GO:0051715)
1.6	9.5	GO:0006742	NADP catabolic process(GO:0006742)
1.6	14.2	GO:0060763	mammary duct terminal end bud growth(GO:0060763)
1.6	4.7	GO:0061300	cerebellum vasculature development(GO:0061300)
1.5	1.5	GO:0097212	lysosomal membrane organization(GO:0097212)
1.5	7.5	GO:0009441	glycolate metabolic process(GO:0009441)
1.5	23.6	GO:0006707	cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
1.4	10.0	GO:0015842	aminergic neurotransmitter loading into synaptic vesicle(GO:0015842)
1.4	4.1	GO:0009253	peptidoglycan metabolic process(GO:0000270) peptidoglycan catabolic process(GO:0009253) negative regulation of natural killer cell differentiation(GO:0032824) negative regulation of natural killer cell differentiation involved in immune response(GO:0032827)
1.4	5.4	GO:0039663	fusion of virus membrane with host plasma membrane(GO:0019064) membrane fusion involved in viral entry into host cell(GO:0039663) multi-organism membrane fusion(GO:0044800)
1.3	5.4	GO:0038108	negative regulation of appetite by leptin-mediated signaling pathway(GO:0038108)
1.3	7.7	GO:0034975	protein folding in endoplasmic reticulum(GO:0034975)
1.3	3.8	GO:0032241	positive regulation of nucleobase-containing compound transport(GO:0032241) regulation of nucleoside transport(GO:0032242) negative regulation of circadian sleep/wake cycle, non-REM sleep(GO:0042323) negative regulation of mucus secretion(GO:0070256)
1.2	18.6	GO:0006957	complement activation, alternative pathway(GO:0006957)
1.2	4.9	GO:0000105	histidine biosynthetic process(GO:0000105)
1.2	6.0	GO:0046110	xanthine catabolic process(GO:0009115) xanthine metabolic process(GO:0046110)
1.2	7.1	GO:0006172	ADP biosynthetic process(GO:0006172)
1.2	7.1	GO:0010890	positive regulation of sequestering of triglyceride(GO:0010890)
1.1	10.3	GO:0006572	tyrosine catabolic process(GO:0006572)
1.1	4.5	GO:0038163	thrombopoietin-mediated signaling pathway(GO:0038163)
1.1	14.5	GO:0006122	mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
1.1	4.3	GO:0014916	regulation of lung blood pressure(GO:0014916)
1.0	32.5	GO:0035634	response to stilbenoid(GO:0035634)
1.0	6.2	GO:0098734	protein depalmitoylation(GO:0002084) macromolecule depalmitoylation(GO:0098734)
1.0	12.2	GO:0052696	flavonoid glucuronidation(GO:0052696) xenobiotic glucuronidation(GO:0052697)
1.0	4.0	GO:0045329	carnitine biosynthetic process(GO:0045329)
1.0	2.9	GO:0006218	uridine catabolic process(GO:0006218) uridine metabolic process(GO:0046108)
1.0	9.6	GO:0051596	methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione(GO:0019243) methylglyoxal catabolic process(GO:0051596) methylglyoxal catabolic process to lactate(GO:0061727)
0.9	6.3	GO:0048861	oncostatin-M-mediated signaling pathway(GO:0038165) leukemia inhibitory factor signaling pathway(GO:0048861)
0.8	2.5	GO:0071579	regulation of zinc ion transport(GO:0071579)
0.8	0.8	GO:0043134	hindgut contraction(GO:0043133) regulation of hindgut contraction(GO:0043134) positive regulation of hindgut contraction(GO:0060450)
0.8	11.3	GO:0035376	sterol import(GO:0035376) cholesterol import(GO:0070508)
0.8	5.6	GO:0006207	'de novo' pyrimidine nucleobase biosynthetic process(GO:0006207) pyrimidine nucleobase biosynthetic process(GO:0019856)
0.8	4.8	GO:0001980	regulation of systemic arterial blood pressure by ischemic conditions(GO:0001980)
0.8	5.6	GO:0071321	cellular response to cGMP(GO:0071321)
0.8	4.7	GO:0016557	peroxisome membrane biogenesis(GO:0016557)
0.8	4.7	GO:1903071	positive regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903071)
0.8	10.2	GO:0001867	complement activation, lectin pathway(GO:0001867)
0.7	14.2	GO:0070255	regulation of mucus secretion(GO:0070255)
0.7	0.7	GO:0002874	regulation of chronic inflammatory response to antigenic stimulus(GO:0002874)
0.7	12.3	GO:0033539	fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
0.7	8.6	GO:0006123	mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.7	5.0	GO:0046618	drug export(GO:0046618)
0.7	2.1	GO:0061144	alveolar secondary septum development(GO:0061144)
0.7	11.2	GO:0006105	succinate metabolic process(GO:0006105)
0.7	1.4	GO:1902109	negative regulation of mitochondrial membrane permeability involved in apoptotic process(GO:1902109)
0.7	8.3	GO:0070863	positive regulation of protein exit from endoplasmic reticulum(GO:0070863)
0.7	5.3	GO:0009446	putrescine biosynthetic process(GO:0009446)
0.6	2.6	GO:0043376	regulation of CD8-positive, alpha-beta T cell differentiation(GO:0043376)
0.6	6.5	GO:0006995	cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.6	4.5	GO:0016103	diterpenoid catabolic process(GO:0016103) retinoic acid catabolic process(GO:0034653)
0.6	7.7	GO:0019367	fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.6	3.2	GO:0010636	positive regulation of mitochondrial fusion(GO:0010636)
0.6	2.4	GO:0030210	heparin biosynthetic process(GO:0030210)
0.6	1.8	GO:0016256	N-glycan processing to lysosome(GO:0016256)
0.6	3.0	GO:0098886	modification of dendritic spine(GO:0098886)
0.6	10.0	GO:0048312	intracellular distribution of mitochondria(GO:0048312)
0.6	1.7	GO:1903093	regulation of protein K48-linked deubiquitination(GO:1903093) negative regulation of protein K48-linked deubiquitination(GO:1903094) negative regulation of ubiquitin-specific protease activity(GO:2000157)
0.6	1.7	GO:1903920	positive regulation of actin filament severing(GO:1903920)
0.6	2.3	GO:0015744	succinate transport(GO:0015744)
0.6	1.7	GO:0051792	medium-chain fatty acid biosynthetic process(GO:0051792)
0.5	3.3	GO:0010730	negative regulation of hydrogen peroxide biosynthetic process(GO:0010730)
0.5	4.2	GO:0006741	NADP biosynthetic process(GO:0006741)
0.5	2.1	GO:1903976	negative regulation of glial cell migration(GO:1903976)
0.5	5.7	GO:0098789	pre-mRNA cleavage required for polyadenylation(GO:0098789)
0.5	2.6	GO:0048619	embryonic genitalia morphogenesis(GO:0030538) embryonic hindgut morphogenesis(GO:0048619)
0.5	4.6	GO:0019532	oxalate transport(GO:0019532)
0.5	4.6	GO:0006528	asparagine metabolic process(GO:0006528)
0.5	1.0	GO:0070973	protein localization to endoplasmic reticulum exit site(GO:0070973)
0.5	2.4	GO:0014063	negative regulation of serotonin secretion(GO:0014063)
0.5	2.9	GO:0010641	positive regulation of platelet-derived growth factor receptor signaling pathway(GO:0010641)
0.5	1.9	GO:1902037	negative regulation of hematopoietic stem cell differentiation(GO:1902037)
0.5	1.4	GO:0010635	regulation of mitochondrial fusion(GO:0010635) negative regulation of mitochondrial fusion(GO:0010637)
0.4	5.8	GO:0032000	positive regulation of fatty acid beta-oxidation(GO:0032000)
0.4	2.2	GO:0006548	histidine metabolic process(GO:0006547) histidine catabolic process(GO:0006548)
0.4	5.7	GO:0016554	cytidine to uridine editing(GO:0016554)
0.4	2.6	GO:0007597	blood coagulation, intrinsic pathway(GO:0007597)
0.4	2.1	GO:0072363	regulation of glycolytic process by positive regulation of transcription from RNA polymerase II promoter(GO:0072363)
0.4	3.0	GO:0046874	quinolinate metabolic process(GO:0046874)
0.4	20.1	GO:0097031	NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.4	2.5	GO:0090209	negative regulation of triglyceride metabolic process(GO:0090209)
0.4	1.7	GO:0032417	positive regulation of sodium:proton antiporter activity(GO:0032417)
0.4	2.9	GO:1902861	cellular response to cisplatin(GO:0072719) copper ion import across plasma membrane(GO:0098705) copper ion import into cell(GO:1902861)
0.4	10.2	GO:0006491	N-glycan processing(GO:0006491)
0.4	2.8	GO:0017062	respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551)
0.4	1.2	GO:1903233	regulation of calcium ion-dependent exocytosis of neurotransmitter(GO:1903233)
0.4	1.2	GO:0038189	neuropilin signaling pathway(GO:0038189) VEGF-activated neuropilin signaling pathway(GO:0038190)
0.4	1.2	GO:0035627	ceramide transport(GO:0035627)
0.4	1.2	GO:0033189	response to vitamin A(GO:0033189)
0.4	1.2	GO:0090673	endothelial cell-matrix adhesion(GO:0090673)
0.4	3.4	GO:0006703	estrogen biosynthetic process(GO:0006703)
0.4	3.4	GO:0061709	reticulophagy(GO:0061709)
0.4	3.0	GO:0006824	cobalt ion transport(GO:0006824)
0.4	2.5	GO:0090234	regulation of kinetochore assembly(GO:0090234)
0.4	0.7	GO:1903279	regulation of calcium:sodium antiporter activity(GO:1903279)
0.4	4.6	GO:0006390	transcription from mitochondrial promoter(GO:0006390)
0.3	1.4	GO:0021917	pancreatic A cell development(GO:0003322) forebrain-midbrain boundary formation(GO:0021905) somatic motor neuron fate commitment(GO:0021917) regulation of transcription from RNA polymerase II promoter involved in somatic motor neuron fate commitment(GO:0021918) sensory neuron migration(GO:1904937)
0.3	1.0	GO:0072592	oxygen metabolic process(GO:0072592)
0.3	1.3	GO:0042776	mitochondrial ATP synthesis coupled proton transport(GO:0042776)
0.3	5.6	GO:0015937	coenzyme A biosynthetic process(GO:0015937)
0.3	1.6	GO:0042412	taurine biosynthetic process(GO:0042412)
0.3	1.0	GO:0030070	insulin processing(GO:0030070)
0.3	2.6	GO:0006777	Mo-molybdopterin cofactor biosynthetic process(GO:0006777) Mo-molybdopterin cofactor metabolic process(GO:0019720)
0.3	2.6	GO:0032237	activation of store-operated calcium channel activity(GO:0032237)
0.3	6.6	GO:0036295	cellular response to increased oxygen levels(GO:0036295)
0.3	0.3	GO:0003130	BMP signaling pathway involved in heart induction(GO:0003130) endodermal-mesodermal cell signaling(GO:0003133) endodermal-mesodermal cell signaling involved in heart induction(GO:0003134)
0.3	0.6	GO:0021941	negative regulation of cerebellar granule cell precursor proliferation(GO:0021941)
0.3	1.5	GO:0006421	asparaginyl-tRNA aminoacylation(GO:0006421)
0.3	3.0	GO:0006646	phosphatidylethanolamine biosynthetic process(GO:0006646)
0.3	0.9	GO:1903286	regulation of potassium ion import(GO:1903286)
0.3	4.5	GO:0051151	negative regulation of smooth muscle cell differentiation(GO:0051151)
0.3	3.5	GO:0042637	catagen(GO:0042637)
0.3	0.8	GO:0032474	otolith morphogenesis(GO:0032474)
0.3	7.6	GO:0015986	energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.3	2.8	GO:0006283	transcription-coupled nucleotide-excision repair(GO:0006283)
0.3	2.2	GO:1903300	negative regulation of glucokinase activity(GO:0033132) negative regulation of hexokinase activity(GO:1903300)
0.3	1.4	GO:0035063	nuclear speck organization(GO:0035063)
0.3	6.8	GO:1901897	regulation of relaxation of cardiac muscle(GO:1901897)
0.3	2.2	GO:0042985	negative regulation of amyloid precursor protein biosynthetic process(GO:0042985)
0.3	14.4	GO:0014003	oligodendrocyte development(GO:0014003)
0.3	0.5	GO:0009644	response to high light intensity(GO:0009644)
0.3	2.1	GO:0006689	ganglioside catabolic process(GO:0006689) oligosaccharide catabolic process(GO:0009313)
0.3	3.4	GO:0006120	mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.2	2.7	GO:0071318	cellular response to ATP(GO:0071318)
0.2	0.7	GO:0015817	histidine transport(GO:0015817)
0.2	2.3	GO:0098881	exocytic insertion of neurotransmitter receptor to plasma membrane(GO:0098881) exocytic insertion of neurotransmitter receptor to postsynaptic membrane(GO:0098967)
0.2	1.2	GO:0035752	lysosomal lumen pH elevation(GO:0035752)
0.2	1.6	GO:0046543	development of secondary female sexual characteristics(GO:0046543)
0.2	2.5	GO:0045198	establishment of epithelial cell apical/basal polarity(GO:0045198)
0.2	1.4	GO:0072378	blood coagulation, fibrin clot formation(GO:0072378)
0.2	8.2	GO:0022904	respiratory electron transport chain(GO:0022904)
0.2	0.9	GO:0010747	positive regulation of plasma membrane long-chain fatty acid transport(GO:0010747)
0.2	0.9	GO:1904428	negative regulation of tubulin deacetylation(GO:1904428)
0.2	0.9	GO:0009298	GDP-mannose biosynthetic process(GO:0009298)
0.2	1.3	GO:0070459	prolactin secretion(GO:0070459)
0.2	0.2	GO:1903760	regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization(GO:1903760)
0.2	1.7	GO:0061366	behavioral response to chemical pain(GO:0061366) behavioral response to formalin induced pain(GO:0061368)
0.2	0.4	GO:1990705	cholangiocyte proliferation(GO:1990705)
0.2	0.6	GO:0046901	tetrahydrofolylpolyglutamate biosynthetic process(GO:0046901)
0.2	2.1	GO:0006003	fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.2	0.8	GO:0007352	zygotic specification of dorsal/ventral axis(GO:0007352) positive regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry(GO:1900224)
0.2	3.1	GO:0016576	histone dephosphorylation(GO:0016576)
0.2	1.0	GO:0036151	phosphatidylcholine acyl-chain remodeling(GO:0036151)
0.2	0.6	GO:0071879	positive regulation of adrenergic receptor signaling pathway(GO:0071879)
0.2	1.6	GO:0045541	negative regulation of cholesterol biosynthetic process(GO:0045541) negative regulation of cholesterol metabolic process(GO:0090206)
0.2	3.4	GO:0060732	positive regulation of inositol phosphate biosynthetic process(GO:0060732)
0.2	0.6	GO:0021558	trochlear nerve development(GO:0021558)
0.2	3.1	GO:0006614	SRP-dependent cotranslational protein targeting to membrane(GO:0006614)
0.2	1.2	GO:0039534	negative regulation of MDA-5 signaling pathway(GO:0039534)
0.2	1.3	GO:0061732	mitochondrial acetyl-CoA biosynthetic process from pyruvate(GO:0061732)
0.2	16.8	GO:0042446	hormone biosynthetic process(GO:0042446)
0.2	3.6	GO:0035814	negative regulation of renal sodium excretion(GO:0035814)
0.2	0.9	GO:0018343	protein farnesylation(GO:0018343)
0.2	3.9	GO:0021684	cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.2	0.4	GO:0045362	regulation of interleukin-1 biosynthetic process(GO:0045360) positive regulation of interleukin-1 biosynthetic process(GO:0045362)
0.2	2.4	GO:0015747	urate transport(GO:0015747)
0.2	0.7	GO:0017187	peptidyl-glutamic acid carboxylation(GO:0017187)
0.2	1.1	GO:0061525	hindgut development(GO:0061525)
0.2	3.6	GO:0015701	bicarbonate transport(GO:0015701)
0.2	1.8	GO:0006686	sphingomyelin biosynthetic process(GO:0006686)
0.2	2.7	GO:0031581	hemidesmosome assembly(GO:0031581)
0.2	3.4	GO:0001580	detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.2	0.3	GO:0007197	adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197) phospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway(GO:0007207)
0.2	1.0	GO:2001045	negative regulation of integrin-mediated signaling pathway(GO:2001045)
0.2	0.5	GO:0060437	lung growth(GO:0060437)
0.2	4.0	GO:0010818	T cell chemotaxis(GO:0010818)
0.2	1.2	GO:0010756	positive regulation of plasminogen activation(GO:0010756)
0.2	1.2	GO:0042636	negative regulation of hair cycle(GO:0042636)
0.2	1.9	GO:0060689	cell differentiation involved in salivary gland development(GO:0060689)
0.2	5.8	GO:0030262	apoptotic nuclear changes(GO:0030262)
0.2	3.2	GO:0006662	glycerol ether metabolic process(GO:0006662)
0.2	7.8	GO:0030195	negative regulation of blood coagulation(GO:0030195) negative regulation of hemostasis(GO:1900047)
0.2	0.8	GO:1904059	regulation of locomotor rhythm(GO:1904059)
0.2	1.0	GO:0070070	proton-transporting V-type ATPase complex assembly(GO:0070070) vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
0.2	0.5	GO:0086047	membrane depolarization during Purkinje myocyte cell action potential(GO:0086047)
0.2	9.1	GO:0048873	homeostasis of number of cells within a tissue(GO:0048873)
0.2	5.0	GO:0009303	rRNA transcription(GO:0009303)
0.2	1.3	GO:0090074	negative regulation of protein homodimerization activity(GO:0090074)
0.2	0.6	GO:1900149	positive regulation of Schwann cell migration(GO:1900149) positive regulation of glial cell migration(GO:1903977)
0.2	1.7	GO:0051665	membrane raft localization(GO:0051665)
0.2	4.0	GO:0031987	locomotion involved in locomotory behavior(GO:0031987)
0.2	0.5	GO:0036092	phosphatidylinositol-3-phosphate biosynthetic process(GO:0036092)
0.2	1.2	GO:1990118	sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.2	2.4	GO:2001013	epithelial cell proliferation involved in renal tubule morphogenesis(GO:2001013)
0.2	0.3	GO:1990926	short-term synaptic potentiation(GO:1990926)
0.1	6.1	GO:0030212	hyaluronan metabolic process(GO:0030212)
0.1	2.2	GO:0046415	urate metabolic process(GO:0046415)
0.1	1.6	GO:0070166	enamel mineralization(GO:0070166)
0.1	2.5	GO:0072189	ureter development(GO:0072189)
0.1	5.1	GO:1900078	positive regulation of cellular response to insulin stimulus(GO:1900078)
0.1	4.3	GO:0050892	intestinal absorption(GO:0050892)
0.1	6.3	GO:0002089	lens morphogenesis in camera-type eye(GO:0002089)
0.1	1.9	GO:0048102	autophagic cell death(GO:0048102)
0.1	0.5	GO:0016062	response to light intensity(GO:0009642) adaptation of rhodopsin mediated signaling(GO:0016062) light adaption(GO:0036367)
0.1	2.2	GO:0046697	decidualization(GO:0046697)
0.1	14.9	GO:0009166	nucleotide catabolic process(GO:0009166)
0.1	1.9	GO:0000301	retrograde transport, vesicle recycling within Golgi(GO:0000301)
0.1	1.3	GO:0043402	glucocorticoid mediated signaling pathway(GO:0043402)
0.1	0.5	GO:0019509	L-methionine biosynthetic process from methylthioadenosine(GO:0019509)
0.1	0.4	GO:2000630	positive regulation of miRNA metabolic process(GO:2000630)
0.1	0.8	GO:0061589	calcium activated phosphatidylserine scrambling(GO:0061589)
0.1	3.6	GO:0019373	epoxygenase P450 pathway(GO:0019373)
0.1	3.0	GO:0001886	endothelial cell morphogenesis(GO:0001886)
0.1	2.8	GO:0046325	negative regulation of glucose import(GO:0046325)
0.1	2.2	GO:0010884	positive regulation of lipid storage(GO:0010884)
0.1	1.0	GO:2001183	negative regulation of interleukin-12 secretion(GO:2001183)
0.1	0.5	GO:0098964	dendritic transport of ribonucleoprotein complex(GO:0098961) dendritic transport of messenger ribonucleoprotein complex(GO:0098963) anterograde dendritic transport of messenger ribonucleoprotein complex(GO:0098964)
0.1	0.5	GO:0021586	pons maturation(GO:0021586)
0.1	0.9	GO:0019695	choline metabolic process(GO:0019695)
0.1	0.9	GO:0060665	regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling(GO:0060665)
0.1	0.8	GO:0032049	cardiolipin biosynthetic process(GO:0032049)
0.1	0.3	GO:0000960	mitochondrial RNA catabolic process(GO:0000957) regulation of mitochondrial RNA catabolic process(GO:0000960)
0.1	1.3	GO:0032780	negative regulation of ATPase activity(GO:0032780)
0.1	0.6	GO:1902163	negative regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902163)
0.1	1.1	GO:0043951	negative regulation of cAMP-mediated signaling(GO:0043951)
0.1	0.2	GO:0032470	positive regulation of endoplasmic reticulum calcium ion concentration(GO:0032470) maintenance of mitochondrion location(GO:0051659)
0.1	6.5	GO:0045669	positive regulation of osteoblast differentiation(GO:0045669)
0.1	14.0	GO:0006958	complement activation, classical pathway(GO:0006958)
0.1	3.3	GO:1901522	positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus(GO:1901522)
0.1	0.7	GO:0038003	opioid receptor signaling pathway(GO:0038003)
0.1	0.9	GO:0060136	embryonic process involved in female pregnancy(GO:0060136)
0.1	1.4	GO:0033234	negative regulation of protein sumoylation(GO:0033234)
0.1	8.5	GO:0007586	digestion(GO:0007586)
0.1	0.4	GO:0060024	rhythmic synaptic transmission(GO:0060024)
0.1	0.4	GO:0070781	protein biotinylation(GO:0009305) response to biotin(GO:0070781) histone biotinylation(GO:0071110)
0.1	1.1	GO:0035269	protein O-linked mannosylation(GO:0035269)
0.1	2.0	GO:0043981	histone H4-K5 acetylation(GO:0043981) histone H4-K8 acetylation(GO:0043982)
0.1	0.6	GO:0043691	reverse cholesterol transport(GO:0043691)
0.1	0.8	GO:1904294	positive regulation of ERAD pathway(GO:1904294)
0.1	0.2	GO:0030007	cellular potassium ion homeostasis(GO:0030007)
0.1	0.6	GO:0007253	cytoplasmic sequestering of NF-kappaB(GO:0007253)
0.1	1.4	GO:0071501	response to sterol depletion(GO:0006991) SREBP signaling pathway(GO:0032933) cellular response to sterol depletion(GO:0071501)
0.1	2.2	GO:0046513	ceramide biosynthetic process(GO:0046513)
0.1	0.2	GO:0045763	negative regulation of cellular amine metabolic process(GO:0033239) negative regulation of cellular amino acid metabolic process(GO:0045763)
0.1	1.0	GO:0048386	positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
0.1	3.0	GO:0003298	physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.1	1.3	GO:0090435	protein localization to nuclear envelope(GO:0090435)
0.1	1.2	GO:0006488	dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.1	0.4	GO:0098957	anterograde axonal transport of mitochondrion(GO:0098957)
0.1	1.3	GO:0050434	positive regulation of viral transcription(GO:0050434)
0.1	0.8	GO:0070236	negative regulation of activation-induced cell death of T cells(GO:0070236)
0.1	0.9	GO:1902902	negative regulation of autophagosome assembly(GO:1902902)
0.1	2.5	GO:0032011	ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.1	0.4	GO:1903691	positive regulation of wound healing, spreading of epidermal cells(GO:1903691)
0.1	0.7	GO:0033227	dsRNA transport(GO:0033227)
0.1	0.5	GO:0030050	vesicle transport along actin filament(GO:0030050)
0.1	0.5	GO:0060028	convergent extension involved in axis elongation(GO:0060028)
0.1	1.3	GO:0003334	keratinocyte development(GO:0003334)
0.1	2.0	GO:0051560	mitochondrial calcium ion homeostasis(GO:0051560)
0.1	4.8	GO:0031638	zymogen activation(GO:0031638)
0.1	0.8	GO:0031937	positive regulation of chromatin silencing(GO:0031937)
0.1	1.1	GO:1902259	regulation of delayed rectifier potassium channel activity(GO:1902259)
0.1	0.4	GO:0070423	nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway(GO:0035872) nucleotide-binding oligomerization domain containing signaling pathway(GO:0070423) nucleotide-binding oligomerization domain containing 2 signaling pathway(GO:0070431)
0.1	3.0	GO:0045840	positive regulation of mitotic nuclear division(GO:0045840)
0.1	3.6	GO:0006749	glutathione metabolic process(GO:0006749)
0.1	1.4	GO:0045948	positive regulation of translational initiation(GO:0045948)
0.1	0.8	GO:0031272	regulation of pseudopodium assembly(GO:0031272)
0.1	3.0	GO:0006687	glycosphingolipid metabolic process(GO:0006687)
0.1	0.4	GO:0060766	negative regulation of androgen receptor signaling pathway(GO:0060766)
0.1	4.7	GO:0048168	regulation of neuronal synaptic plasticity(GO:0048168)
0.1	0.7	GO:1900003	regulation of serine-type endopeptidase activity(GO:1900003) negative regulation of serine-type endopeptidase activity(GO:1900004) regulation of serine-type peptidase activity(GO:1902571) negative regulation of serine-type peptidase activity(GO:1902572)
0.1	2.0	GO:0042149	cellular response to glucose starvation(GO:0042149)
0.1	1.2	GO:0007190	activation of adenylate cyclase activity(GO:0007190)
0.1	0.3	GO:0006627	protein processing involved in protein targeting to mitochondrion(GO:0006627)
0.1	0.4	GO:0003350	pulmonary myocardium development(GO:0003350)
0.1	0.7	GO:0019800	peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.1	0.7	GO:1901621	negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:1901621)
0.1	1.1	GO:0000038	very long-chain fatty acid metabolic process(GO:0000038)
0.1	12.2	GO:0006814	sodium ion transport(GO:0006814)
0.1	2.8	GO:0030819	positive regulation of cAMP biosynthetic process(GO:0030819)
0.1	1.4	GO:0000132	establishment of mitotic spindle orientation(GO:0000132)
0.1	3.1	GO:0001707	mesoderm formation(GO:0001707)
0.1	1.2	GO:2000114	regulation of establishment of cell polarity(GO:2000114)
0.1	5.2	GO:0090090	negative regulation of canonical Wnt signaling pathway(GO:0090090)
0.1	1.1	GO:0045736	negative regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045736) negative regulation of cyclin-dependent protein kinase activity(GO:1904030)
0.1	1.4	GO:0071542	dopaminergic neuron differentiation(GO:0071542)
0.1	0.2	GO:0030222	eosinophil differentiation(GO:0030222)
0.1	0.2	GO:0071596	ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596)
0.0	7.4	GO:0007050	cell cycle arrest(GO:0007050)
0.0	11.2	GO:0016042	lipid catabolic process(GO:0016042)
0.0	0.3	GO:0006654	phosphatidic acid biosynthetic process(GO:0006654)
0.0	1.4	GO:0030325	adrenal gland development(GO:0030325)
0.0	0.6	GO:0007288	sperm axoneme assembly(GO:0007288)
0.0	0.3	GO:2001269	positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:2001269)
0.0	0.4	GO:1900119	positive regulation of execution phase of apoptosis(GO:1900119)
0.0	0.3	GO:0007256	activation of JNKK activity(GO:0007256)
0.0	0.1	GO:0071799	response to prostaglandin D(GO:0071798) cellular response to prostaglandin D stimulus(GO:0071799)
0.0	1.2	GO:0003299	muscle hypertrophy in response to stress(GO:0003299) cardiac muscle adaptation(GO:0014887) cardiac muscle hypertrophy in response to stress(GO:0014898)
0.0	0.6	GO:0061179	negative regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061179)
0.0	0.7	GO:0048387	negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.0	1.4	GO:0042036	negative regulation of cytokine biosynthetic process(GO:0042036)
0.0	2.0	GO:0042771	intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:0042771)
0.0	2.4	GO:0032024	positive regulation of insulin secretion(GO:0032024)
0.0	1.5	GO:0007339	binding of sperm to zona pellucida(GO:0007339)
0.0	1.1	GO:0035066	positive regulation of histone acetylation(GO:0035066)
0.0	1.5	GO:0060351	cartilage development involved in endochondral bone morphogenesis(GO:0060351)
0.0	0.4	GO:0098728	germ-line stem cell division(GO:0042078) male germ-line stem cell asymmetric division(GO:0048133) germline stem cell asymmetric division(GO:0098728)
0.0	0.3	GO:0010764	negative regulation of fibroblast migration(GO:0010764) negative regulation of synaptic vesicle exocytosis(GO:2000301)
0.0	3.9	GO:1903955	positive regulation of establishment of protein localization to mitochondrion(GO:1903749) positive regulation of protein targeting to mitochondrion(GO:1903955)
0.0	0.8	GO:0034587	piRNA metabolic process(GO:0034587)
0.0	0.4	GO:0032927	positive regulation of activin receptor signaling pathway(GO:0032927)
0.0	0.8	GO:0050962	detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962)
0.0	1.4	GO:0007214	gamma-aminobutyric acid signaling pathway(GO:0007214)
0.0	3.0	GO:0061077	chaperone-mediated protein folding(GO:0061077)
0.0	0.8	GO:0031069	hair follicle morphogenesis(GO:0031069)
0.0	0.5	GO:0030823	regulation of cGMP metabolic process(GO:0030823)
0.0	0.1	GO:0008050	female courtship behavior(GO:0008050)
0.0	1.3	GO:1900087	positive regulation of G1/S transition of mitotic cell cycle(GO:1900087)
0.0	0.4	GO:0018298	protein-chromophore linkage(GO:0018298)
0.0	0.8	GO:0045956	positive regulation of calcium ion-dependent exocytosis(GO:0045956)
0.0	0.3	GO:0061002	negative regulation of dendritic spine morphogenesis(GO:0061002)
0.0	0.0	GO:0010841	positive regulation of circadian sleep/wake cycle, wakefulness(GO:0010841)
0.0	0.1	GO:0070681	glutaminyl-tRNAGln biosynthesis via transamidation(GO:0070681)
0.0	0.6	GO:0007205	protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.0	0.4	GO:1901203	positive regulation of extracellular matrix assembly(GO:1901203) regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904259) positive regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904261) basement membrane assembly involved in embryonic body morphogenesis(GO:2001197)
0.0	5.6	GO:0006631	fatty acid metabolic process(GO:0006631)
0.0	0.3	GO:0006308	DNA catabolic process(GO:0006308)
0.0	0.4	GO:0070544	histone H3-K36 demethylation(GO:0070544)
0.0	1.5	GO:0008637	apoptotic mitochondrial changes(GO:0008637)
0.0	0.2	GO:0007635	chemosensory behavior(GO:0007635)
0.0	0.4	GO:0007340	acrosome reaction(GO:0007340)
0.0	0.6	GO:0006695	cholesterol biosynthetic process(GO:0006695)
0.0	0.2	GO:0007342	fusion of sperm to egg plasma membrane(GO:0007342)
0.0	0.1	GO:1904491	protein localization to ciliary transition zone(GO:1904491)
0.0	0.1	GO:0015904	tetracycline transport(GO:0015904)
0.0	0.8	GO:0002088	lens development in camera-type eye(GO:0002088)
0.0	2.8	GO:0030324	lung development(GO:0030324)
0.0	0.6	GO:1901998	toxin transport(GO:1901998)
0.0	0.1	GO:0048550	negative regulation of pinocytosis(GO:0048550)
0.0	0.3	GO:0030150	protein import into mitochondrial matrix(GO:0030150)
0.0	0.4	GO:0035094	response to nicotine(GO:0035094)
0.0	0.1	GO:0035262	gonad morphogenesis(GO:0035262)
0.0	2.3	GO:0060041	retina development in camera-type eye(GO:0060041)
0.0	0.2	GO:2000060	positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:2000060)
0.0	0.3	GO:1903831	acetylcholine receptor signaling pathway(GO:0095500) signal transduction involved in cellular response to ammonium ion(GO:1903831) response to acetylcholine(GO:1905144) cellular response to acetylcholine(GO:1905145)
0.0	0.8	GO:0006506	GPI anchor metabolic process(GO:0006505) GPI anchor biosynthetic process(GO:0006506)
0.0	0.6	GO:0061099	negative regulation of protein tyrosine kinase activity(GO:0061099)
0.0	0.3	GO:0010718	positive regulation of epithelial to mesenchymal transition(GO:0010718)
0.0	0.1	GO:0035524	proline transmembrane transport(GO:0035524)
0.0	0.1	GO:0035021	negative regulation of Rac protein signal transduction(GO:0035021)
0.0	0.1	GO:2000727	positive regulation of cardiocyte differentiation(GO:1905209) positive regulation of cardiac muscle cell differentiation(GO:2000727)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
9.4	103.0	GO:0034363	intermediate-density lipoprotein particle(GO:0034363)
4.9	19.5	GO:0045281	mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283)
3.5	35.0	GO:0089717	spanning component of plasma membrane(GO:0044214) spanning component of membrane(GO:0089717)
3.4	10.1	GO:0036020	endolysosome membrane(GO:0036020)
2.5	12.6	GO:0044316	cone cell pedicle(GO:0044316)
2.3	9.4	GO:0017133	mitochondrial electron transfer flavoprotein complex(GO:0017133) electron transfer flavoprotein complex(GO:0045251)
2.3	9.2	GO:0097636	platelet dense granule membrane(GO:0031088) intrinsic component of autophagosome membrane(GO:0097636) integral component of autophagosome membrane(GO:0097637)
1.9	5.6	GO:0098855	HCN channel complex(GO:0098855)
1.8	9.1	GO:0017177	glucosidase II complex(GO:0017177)
1.8	5.4	GO:1902636	kinociliary basal body(GO:1902636)
1.6	4.7	GO:0042720	mitochondrial inner membrane peptidase complex(GO:0042720)
1.5	16.4	GO:0045098	type III intermediate filament(GO:0045098)
1.5	17.4	GO:0042627	chylomicron(GO:0042627)
1.3	14.8	GO:0005750	mitochondrial respiratory chain complex III(GO:0005750)
1.0	5.9	GO:0097226	sperm mitochondrial sheath(GO:0097226)
1.0	9.6	GO:0033116	endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.9	2.6	GO:0019008	molybdopterin synthase complex(GO:0019008)
0.8	3.3	GO:0032280	axonemal microtubule(GO:0005879) symmetric synapse(GO:0032280)
0.7	3.5	GO:0098560	cytoplasmic side of late endosome membrane(GO:0098560)
0.7	2.1	GO:0043540	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex(GO:0043540)
0.7	6.2	GO:0000275	mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275) proton-transporting ATP synthase complex, catalytic core F(1)(GO:0045261)
0.7	4.8	GO:1990584	cardiac Troponin complex(GO:1990584)
0.7	18.2	GO:0034364	high-density lipoprotein particle(GO:0034364)
0.7	3.3	GO:0030868	smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425)
0.7	11.1	GO:0005751	mitochondrial respiratory chain complex IV(GO:0005751)
0.6	5.6	GO:0005579	membrane attack complex(GO:0005579)
0.6	7.9	GO:0072546	ER membrane protein complex(GO:0072546)
0.6	7.1	GO:0033180	proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.6	11.5	GO:0061702	inflammasome complex(GO:0061702)
0.5	5.2	GO:0005890	sodium:potassium-exchanging ATPase complex(GO:0005890)
0.5	8.9	GO:0046581	intercellular canaliculus(GO:0046581)
0.5	34.8	GO:0034707	chloride channel complex(GO:0034707)
0.4	3.1	GO:0005785	signal recognition particle receptor complex(GO:0005785)
0.4	3.0	GO:0097444	spine apparatus(GO:0097444)
0.4	1.2	GO:0014801	longitudinal sarcoplasmic reticulum(GO:0014801)
0.4	4.3	GO:0045179	apical cortex(GO:0045179)
0.4	18.9	GO:0005747	mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.4	1.4	GO:0002111	BRCA2-BRAF35 complex(GO:0002111)
0.4	2.5	GO:0097550	transcriptional preinitiation complex(GO:0097550)
0.4	10.6	GO:0005779	integral component of peroxisomal membrane(GO:0005779)
0.4	23.8	GO:0005778	peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.3	3.8	GO:0032541	cortical endoplasmic reticulum(GO:0032541)
0.3	1.0	GO:0043291	RAVE complex(GO:0043291)
0.3	3.6	GO:0031983	vesicle lumen(GO:0031983)
0.3	1.3	GO:0005608	laminin-3 complex(GO:0005608)
0.3	7.5	GO:0000421	autophagosome membrane(GO:0000421)
0.3	8.6	GO:0031528	microvillus membrane(GO:0031528)
0.3	1.1	GO:0097598	sperm cytoplasmic droplet(GO:0097598)
0.3	1.4	GO:0032437	cuticular plate(GO:0032437)
0.3	5.7	GO:0005847	mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.3	3.8	GO:1990635	proximal dendrite(GO:1990635)
0.3	7.1	GO:0005665	DNA-directed RNA polymerase II, core complex(GO:0005665)
0.3	37.6	GO:0005777	peroxisome(GO:0005777) microbody(GO:0042579)
0.2	66.2	GO:0072562	blood microparticle(GO:0072562)
0.2	2.2	GO:0031211	serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.2	8.9	GO:0005790	smooth endoplasmic reticulum(GO:0005790)
0.2	3.6	GO:0000276	mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.2	0.9	GO:1990037	Lewy body core(GO:1990037)
0.2	21.4	GO:0005811	lipid particle(GO:0005811)
0.2	4.1	GO:0032279	asymmetric synapse(GO:0032279) neuron to neuron synapse(GO:0098984)
0.2	11.5	GO:0009295	nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.2	1.3	GO:0045254	pyruvate dehydrogenase complex(GO:0045254)
0.2	2.1	GO:0070469	respiratory chain(GO:0070469)
0.2	6.1	GO:0042588	zymogen granule(GO:0042588)
0.2	0.8	GO:0032444	activin responsive factor complex(GO:0032444) SMAD2-SMAD3 protein complex(GO:0071144)
0.2	0.8	GO:1990923	PET complex(GO:1990923)
0.2	0.6	GO:0072534	perineuronal net(GO:0072534)
0.2	0.9	GO:0070069	cytochrome complex(GO:0070069)
0.2	3.4	GO:0031083	BLOC-1 complex(GO:0031083)
0.1	1.2	GO:0001652	granular component(GO:0001652)
0.1	1.2	GO:0045239	tricarboxylic acid cycle enzyme complex(GO:0045239)
0.1	2.0	GO:0017119	Golgi transport complex(GO:0017119)
0.1	11.5	GO:0009925	basal plasma membrane(GO:0009925)
0.1	4.1	GO:0031588	nucleotide-activated protein kinase complex(GO:0031588)
0.1	0.8	GO:0097433	dense body(GO:0097433)
0.1	19.8	GO:0030176	integral component of endoplasmic reticulum membrane(GO:0030176)
0.1	0.5	GO:0016533	cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
0.1	1.7	GO:0098799	outer mitochondrial membrane protein complex(GO:0098799)
0.1	0.7	GO:0005952	cAMP-dependent protein kinase complex(GO:0005952)
0.1	23.4	GO:0005759	mitochondrial matrix(GO:0005759)
0.1	0.8	GO:0034098	VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.1	37.8	GO:0016324	apical plasma membrane(GO:0016324)
0.1	1.9	GO:0030914	STAGA complex(GO:0030914)
0.1	1.2	GO:0001520	outer dense fiber(GO:0001520)
0.1	7.5	GO:0016529	sarcoplasmic reticulum(GO:0016529)
0.1	0.4	GO:0031314	extrinsic component of mitochondrial inner membrane(GO:0031314)
0.1	9.8	GO:0000118	histone deacetylase complex(GO:0000118)
0.1	3.5	GO:0031526	brush border membrane(GO:0031526)
0.1	2.4	GO:0032588	trans-Golgi network membrane(GO:0032588)
0.1	3.2	GO:0032809	neuronal cell body membrane(GO:0032809)
0.1	0.2	GO:0016939	kinesin II complex(GO:0016939)
0.1	0.8	GO:0000138	Golgi trans cisterna(GO:0000138)
0.1	0.4	GO:0071797	LUBAC complex(GO:0071797)
0.1	0.6	GO:0030485	smooth muscle contractile fiber(GO:0030485)
0.1	0.9	GO:0008385	IkappaB kinase complex(GO:0008385)
0.1	1.8	GO:0045095	keratin filament(GO:0045095)
0.1	1.0	GO:0032593	insulin-responsive compartment(GO:0032593)
0.1	5.4	GO:0005791	rough endoplasmic reticulum(GO:0005791)
0.1	1.2	GO:0008074	guanylate cyclase complex, soluble(GO:0008074)
0.1	1.3	GO:0030057	desmosome(GO:0030057)
0.1	2.2	GO:0005719	nuclear euchromatin(GO:0005719)
0.1	0.6	GO:0002177	manchette(GO:0002177)
0.1	10.2	GO:0043679	axon terminus(GO:0043679)
0.0	6.0	GO:0055037	recycling endosome(GO:0055037)
0.0	0.9	GO:0005797	Golgi medial cisterna(GO:0005797)
0.0	0.6	GO:0016342	catenin complex(GO:0016342)
0.0	0.2	GO:0070722	Tle3-Aes complex(GO:0070722)
0.0	6.7	GO:0005770	late endosome(GO:0005770)
0.0	0.1	GO:0071914	prominosome(GO:0071914)
0.0	58.0	GO:0005783	endoplasmic reticulum(GO:0005783)
0.0	0.7	GO:0044306	neuron projection terminus(GO:0044306)
0.0	1.0	GO:0005614	interstitial matrix(GO:0005614)
0.0	1.6	GO:1990391	DNA repair complex(GO:1990391)
0.0	0.4	GO:0033256	I-kappaB/NF-kappaB complex(GO:0033256)
0.0	0.1	GO:0030956	glutamyl-tRNA(Gln) amidotransferase complex(GO:0030956)
0.0	1.0	GO:0001917	photoreceptor inner segment(GO:0001917)
0.0	0.3	GO:0042788	polysomal ribosome(GO:0042788)
0.0	0.4	GO:0045180	basal cortex(GO:0045180)
0.0	1.7	GO:0019005	SCF ubiquitin ligase complex(GO:0019005)
0.0	0.4	GO:0044292	dendrite terminus(GO:0044292)
0.0	0.4	GO:0005892	acetylcholine-gated channel complex(GO:0005892)
0.0	0.4	GO:0005942	phosphatidylinositol 3-kinase complex(GO:0005942)
0.0	0.4	GO:0005652	nuclear lamina(GO:0005652)
0.0	0.1	GO:0002079	inner acrosomal membrane(GO:0002079)
0.0	0.3	GO:0035102	PRC1 complex(GO:0035102)
0.0	0.2	GO:0035253	ciliary rootlet(GO:0035253)
0.0	4.9	GO:0031966	mitochondrial membrane(GO:0031966)
0.0	0.3	GO:0045120	pronucleus(GO:0045120)
0.0	0.5	GO:0030672	synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
25.7	103.0	GO:0070653	high-density lipoprotein particle receptor binding(GO:0070653)
7.8	23.4	GO:0004613	phosphoenolpyruvate carboxykinase activity(GO:0004611) phosphoenolpyruvate carboxykinase (GTP) activity(GO:0004613)
6.5	19.5	GO:0008177	succinate dehydrogenase (ubiquinone) activity(GO:0008177)
5.8	40.8	GO:0018685	alkane 1-monooxygenase activity(GO:0018685) leukotriene-B4 20-monooxygenase activity(GO:0050051)
5.8	23.2	GO:0004800	thyroxine 5'-deiodinase activity(GO:0004800)
5.0	29.9	GO:0004359	glutaminase activity(GO:0004359)
5.0	14.9	GO:0080130	L-phenylalanine:2-oxoglutarate aminotransferase activity(GO:0080130)
4.9	14.7	GO:0016838	carbon-oxygen lyase activity, acting on phosphates(GO:0016838)
4.7	14.1	GO:0016155	formyltetrahydrofolate dehydrogenase activity(GO:0016155)
4.4	17.8	GO:0004833	tryptophan 2,3-dioxygenase activity(GO:0004833)
4.1	16.3	GO:0015182	L-asparagine transmembrane transporter activity(GO:0015182)
4.1	24.3	GO:0015232	heme transporter activity(GO:0015232)
3.4	10.3	GO:0003868	4-hydroxyphenylpyruvate dioxygenase activity(GO:0003868) quercetin 2,3-dioxygenase activity(GO:0008127)
3.3	10.0	GO:0005009	insulin-activated receptor activity(GO:0005009)
3.2	9.7	GO:0015229	L-ascorbate:sodium symporter activity(GO:0008520) L-ascorbic acid transporter activity(GO:0015229) sodium-dependent L-ascorbate transmembrane transporter activity(GO:0070890)
3.2	19.2	GO:0004850	uridine phosphorylase activity(GO:0004850)
3.0	8.9	GO:0002061	uracil binding(GO:0002058) pyrimidine nucleobase binding(GO:0002061)
2.9	17.4	GO:0060228	phosphatidylcholine-sterol O-acyltransferase activator activity(GO:0060228)
2.8	8.5	GO:0070279	vitamin B6 binding(GO:0070279)
2.8	19.7	GO:0016401	palmitoyl-CoA oxidase activity(GO:0016401)
2.5	10.0	GO:0004058	aromatic-L-amino-acid decarboxylase activity(GO:0004058) L-dopa decarboxylase activity(GO:0036468)
2.4	12.1	GO:0016649	electron-transferring-flavoprotein dehydrogenase activity(GO:0004174) oxidoreductase activity, acting on the CH-NH group of donors, quinone or similar compound as acceptor(GO:0016649)
2.2	8.8	GO:0047016	cholest-5-ene-3-beta,7-alpha-diol 3-beta-dehydrogenase activity(GO:0047016)
2.1	10.7	GO:0035478	chylomicron binding(GO:0035478)
2.1	19.1	GO:0035473	lipase binding(GO:0035473)
2.1	6.3	GO:0003845	11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity(GO:0003845)
2.0	6.1	GO:0004771	sterol esterase activity(GO:0004771)
1.9	5.8	GO:1990698	palmitoleoyltransferase activity(GO:1990698)
1.6	4.7	GO:0004087	carbamoyl-phosphate synthase (ammonia) activity(GO:0004087) carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity(GO:0004088)
1.4	5.7	GO:0016899	oxidoreductase activity, acting on the CH-OH group of donors, oxygen as acceptor(GO:0016899)
1.4	12.2	GO:0005000	vasopressin receptor activity(GO:0005000)
1.3	6.7	GO:0004021	L-alanine:2-oxoglutarate aminotransferase activity(GO:0004021) alanine-oxo-acid transaminase activity(GO:0047635)
1.3	6.5	GO:0003989	acetyl-CoA carboxylase activity(GO:0003989)
1.3	6.3	GO:0004923	leukemia inhibitory factor receptor activity(GO:0004923)
1.3	8.8	GO:0001851	complement component C3b binding(GO:0001851)
1.2	10.0	GO:0016681	ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
1.2	3.6	GO:0004140	dephospho-CoA kinase activity(GO:0004140)
1.2	6.0	GO:0030151	xanthine dehydrogenase activity(GO:0004854) oxidoreductase activity, acting on CH or CH2 groups, NAD or NADP as acceptor(GO:0016726) molybdenum ion binding(GO:0030151) molybdopterin cofactor binding(GO:0043546)
1.1	6.7	GO:0008321	Ral guanyl-nucleotide exchange factor activity(GO:0008321)
1.1	15.6	GO:0003847	1-alkyl-2-acetylglycerophosphocholine esterase activity(GO:0003847)
1.1	8.5	GO:0004416	hydroxyacylglutathione hydrolase activity(GO:0004416)
1.0	3.1	GO:0030158	protein xylosyltransferase activity(GO:0030158)
1.0	4.1	GO:0004329	formate-tetrahydrofolate ligase activity(GO:0004329)
1.0	11.3	GO:0032052	bile acid binding(GO:0032052)
1.0	5.1	GO:0019238	cyclohydrolase activity(GO:0019238)
1.0	2.0	GO:0004921	interleukin-11 receptor activity(GO:0004921) interleukin-11 binding(GO:0019970)
0.9	5.6	GO:0005222	intracellular cAMP activated cation channel activity(GO:0005222)
0.9	4.4	GO:0070287	ferritin receptor activity(GO:0070287)
0.8	2.5	GO:0038052	type 1 metabotropic glutamate receptor binding(GO:0031798) RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding(GO:0038052)
0.8	7.5	GO:0016286	small conductance calcium-activated potassium channel activity(GO:0016286)
0.8	3.2	GO:0043532	angiostatin binding(GO:0043532)
0.8	2.3	GO:0017153	sodium:dicarboxylate symporter activity(GO:0017153)
0.8	3.0	GO:0004307	ethanolaminephosphotransferase activity(GO:0004307)
0.8	4.5	GO:0008401	retinoic acid 4-hydroxylase activity(GO:0008401)
0.7	2.2	GO:0004658	propionyl-CoA carboxylase activity(GO:0004658)
0.7	7.7	GO:0070053	thrombospondin receptor activity(GO:0070053)
0.7	3.5	GO:0030984	kininogen binding(GO:0030984)
0.7	4.1	GO:0008607	phosphorylase kinase regulator activity(GO:0008607)
0.7	4.8	GO:0030172	troponin C binding(GO:0030172)
0.7	4.1	GO:0016019	N-acetylmuramoyl-L-alanine amidase activity(GO:0008745) peptidoglycan receptor activity(GO:0016019)
0.6	7.7	GO:0102336	fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.6	6.2	GO:0098599	palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.6	3.6	GO:0033695	oxidoreductase activity, acting on CH or CH2 groups, quinone or similar compound as acceptor(GO:0033695) caffeine oxidase activity(GO:0034875)
0.6	1.7	GO:0031755	endothelial differentiation G-protein coupled receptor binding(GO:0031753) Edg-2 lysophosphatidic acid receptor binding(GO:0031755)
0.6	10.3	GO:0015245	fatty acid transporter activity(GO:0015245)
0.6	1.7	GO:0003858	3-hydroxybutyrate dehydrogenase activity(GO:0003858)
0.5	2.6	GO:1904288	BAT3 complex binding(GO:1904288)
0.5	3.1	GO:0005047	signal recognition particle binding(GO:0005047)
0.5	1.0	GO:0070991	medium-chain-acyl-CoA dehydrogenase activity(GO:0070991)
0.5	7.2	GO:0004017	adenylate kinase activity(GO:0004017)
0.5	4.6	GO:0003857	3-hydroxyacyl-CoA dehydrogenase activity(GO:0003857)
0.5	3.1	GO:0048248	CXCR3 chemokine receptor binding(GO:0048248)
0.5	18.8	GO:0005452	inorganic anion exchanger activity(GO:0005452)
0.5	1.5	GO:0017099	long-chain-acyl-CoA dehydrogenase activity(GO:0004466) very-long-chain-acyl-CoA dehydrogenase activity(GO:0017099)
0.5	14.5	GO:0004129	cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.5	20.4	GO:0015020	glucuronosyltransferase activity(GO:0015020)
0.5	0.5	GO:0086062	voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006) voltage-gated sodium channel activity involved in Purkinje myocyte action potential(GO:0086062)
0.5	3.4	GO:0004991	parathyroid hormone receptor activity(GO:0004991)
0.5	1.4	GO:0050479	glyceryl-ether monooxygenase activity(GO:0050479)
0.5	11.2	GO:0031078	histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.5	1.8	GO:0036470	tyrosine 3-monooxygenase activator activity(GO:0036470) L-dopa decarboxylase activator activity(GO:0036478)
0.5	1.8	GO:0008113	peptide-methionine (S)-S-oxide reductase activity(GO:0008113)
0.5	0.9	GO:0004127	cytidylate kinase activity(GO:0004127)
0.4	1.8	GO:0003976	UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity(GO:0003976)
0.4	2.7	GO:0016721	superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.4	2.2	GO:0004758	serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.4	1.7	GO:0071796	K6-linked polyubiquitin binding(GO:0071796)
0.4	1.3	GO:0045030	UTP-activated nucleotide receptor activity(GO:0045030)
0.4	3.8	GO:0047498	calcium-dependent phospholipase A2 activity(GO:0047498)
0.4	2.1	GO:0052796	exo-alpha-sialidase activity(GO:0004308) alpha-sialidase activity(GO:0016997) exo-alpha-(2->3)-sialidase activity(GO:0052794) exo-alpha-(2->6)-sialidase activity(GO:0052795) exo-alpha-(2->8)-sialidase activity(GO:0052796)
0.4	3.8	GO:0032795	heterotrimeric G-protein binding(GO:0032795)
0.4	11.9	GO:0016638	oxidoreductase activity, acting on the CH-NH2 group of donors(GO:0016638)
0.4	3.7	GO:0008597	calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.4	9.4	GO:0034185	apolipoprotein binding(GO:0034185)
0.4	33.3	GO:0017080	sodium channel regulator activity(GO:0017080)
0.4	1.2	GO:0043183	vascular endothelial growth factor receptor 1 binding(GO:0043183)
0.4	1.2	GO:0034012	glycerone kinase activity(GO:0004371) FAD-AMP lyase (cyclizing) activity(GO:0034012) triokinase activity(GO:0050354)
0.4	7.8	GO:0030957	Tat protein binding(GO:0030957)
0.4	6.6	GO:0046933	proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.4	1.5	GO:0004816	asparagine-tRNA ligase activity(GO:0004816)
0.4	2.2	GO:0033142	progesterone receptor binding(GO:0033142)
0.4	4.5	GO:0005391	sodium:potassium-exchanging ATPase activity(GO:0005391)
0.4	2.2	GO:0016742	hydroxymethyl-, formyl- and related transferase activity(GO:0016742)
0.4	0.7	GO:0005290	L-histidine transmembrane transporter activity(GO:0005290)
0.4	1.8	GO:0016971	flavin-linked sulfhydryl oxidase activity(GO:0016971)
0.3	3.4	GO:0004886	9-cis retinoic acid receptor activity(GO:0004886)
0.3	1.7	GO:0004315	3-oxoacyl-[acyl-carrier-protein] synthase activity(GO:0004315)
0.3	5.4	GO:0048018	receptor agonist activity(GO:0048018)
0.3	7.7	GO:0009055	electron carrier activity(GO:0009055)
0.3	1.3	GO:0042978	ornithine decarboxylase activator activity(GO:0042978)
0.3	2.0	GO:0004594	pantothenate kinase activity(GO:0004594)
0.3	5.7	GO:0019531	oxalate transmembrane transporter activity(GO:0019531)
0.3	2.2	GO:1901702	urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.3	6.7	GO:0015125	bile acid transmembrane transporter activity(GO:0015125)
0.3	1.8	GO:0047493	sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.3	0.9	GO:0004615	phosphomannomutase activity(GO:0004615)
0.3	9.7	GO:0016709	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen(GO:0016709)
0.3	1.2	GO:0046624	sphingolipid transporter activity(GO:0046624)
0.3	9.0	GO:0004181	metallocarboxypeptidase activity(GO:0004181)
0.3	12.3	GO:0030552	cAMP binding(GO:0030552)
0.3	2.9	GO:0070095	fructose-6-phosphate binding(GO:0070095)
0.3	0.8	GO:0030618	transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618)
0.3	3.3	GO:0030976	thiamine pyrophosphate binding(GO:0030976)
0.3	1.1	GO:0072320	volume-sensitive chloride channel activity(GO:0072320)
0.3	1.3	GO:0034604	pyruvate dehydrogenase activity(GO:0004738) pyruvate dehydrogenase [NAD(P)+] activity(GO:0034603) pyruvate dehydrogenase (NAD+) activity(GO:0034604)
0.3	7.2	GO:0042975	peroxisome proliferator activated receptor binding(GO:0042975)
0.3	1.3	GO:0043423	3-phosphoinositide-dependent protein kinase binding(GO:0043423)
0.3	38.2	GO:0008013	beta-catenin binding(GO:0008013)
0.3	1.0	GO:0030156	benzodiazepine receptor binding(GO:0030156)
0.3	4.8	GO:0015035	protein disulfide oxidoreductase activity(GO:0015035)
0.3	2.5	GO:0043426	MRF binding(GO:0043426)
0.3	1.3	GO:0002046	opsin binding(GO:0002046)
0.2	1.4	GO:0004614	phosphoglucomutase activity(GO:0004614)
0.2	0.9	GO:0031800	type 3 metabotropic glutamate receptor binding(GO:0031800)
0.2	2.7	GO:0046790	virion binding(GO:0046790)
0.2	8.4	GO:0044183	protein binding involved in protein folding(GO:0044183)
0.2	10.3	GO:0004683	calmodulin-dependent protein kinase activity(GO:0004683)
0.2	3.9	GO:0001848	complement binding(GO:0001848)
0.2	2.1	GO:0050291	sphingosine N-acyltransferase activity(GO:0050291)
0.2	0.6	GO:0004326	tetrahydrofolylpolyglutamate synthase activity(GO:0004326)
0.2	43.6	GO:0004252	serine-type endopeptidase activity(GO:0004252)
0.2	0.2	GO:0031177	phosphopantetheine binding(GO:0031177)
0.2	6.2	GO:0044769	ATPase activity, coupled to transmembrane movement of ions, rotational mechanism(GO:0044769) proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.2	2.5	GO:0019855	calcium channel inhibitor activity(GO:0019855)
0.2	2.7	GO:0015279	store-operated calcium channel activity(GO:0015279)
0.2	9.3	GO:0051959	dynein light intermediate chain binding(GO:0051959)
0.2	8.9	GO:0016831	carboxy-lyase activity(GO:0016831)
0.2	0.6	GO:0005026	transforming growth factor beta receptor activity, type II(GO:0005026)
0.2	2.0	GO:0016813	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.2	2.6	GO:0016783	sulfurtransferase activity(GO:0016783)
0.2	1.2	GO:0008294	calcium- and calmodulin-responsive adenylate cyclase activity(GO:0008294)
0.2	4.7	GO:0008137	NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.2	14.8	GO:0005550	pheromone binding(GO:0005550)
0.2	6.5	GO:0005109	frizzled binding(GO:0005109)
0.2	2.0	GO:0043995	histone acetyltransferase activity (H4-K5 specific)(GO:0043995) histone acetyltransferase activity (H4-K8 specific)(GO:0043996) histone acetyltransferase activity (H4-K16 specific)(GO:0046972)
0.2	1.3	GO:0004865	protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.2	0.3	GO:0001847	opsonin receptor activity(GO:0001847)
0.2	10.5	GO:0016811	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides(GO:0016811)
0.2	0.5	GO:0001727	lipid kinase activity(GO:0001727)
0.2	2.4	GO:0016500	protein-hormone receptor activity(GO:0016500)
0.1	0.9	GO:0003828	alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.1	5.9	GO:0008028	monocarboxylic acid transmembrane transporter activity(GO:0008028)
0.1	4.2	GO:0003951	NAD+ kinase activity(GO:0003951)
0.1	1.6	GO:0090599	alpha-glucosidase activity(GO:0090599)
0.1	1.4	GO:0003988	acetyl-CoA C-acyltransferase activity(GO:0003988)
0.1	3.6	GO:0070006	metalloaminopeptidase activity(GO:0070006)
0.1	1.2	GO:0015386	potassium:proton antiporter activity(GO:0015386)
0.1	1.4	GO:1990247	N6-methyladenosine-containing RNA binding(GO:1990247)
0.1	0.9	GO:0097016	L27 domain binding(GO:0097016)
0.1	0.7	GO:0051033	nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033)
0.1	4.4	GO:0008236	serine-type peptidase activity(GO:0008236)
0.1	2.3	GO:0005528	macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.1	0.7	GO:0004985	opioid receptor activity(GO:0004985)
0.1	0.9	GO:0031957	very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.1	2.6	GO:0019825	oxygen binding(GO:0019825)
0.1	2.7	GO:0043395	heparan sulfate proteoglycan binding(GO:0043395)
0.1	3.0	GO:0015114	phosphate ion transmembrane transporter activity(GO:0015114)
0.1	1.4	GO:0003995	acyl-CoA dehydrogenase activity(GO:0003995)
0.1	1.1	GO:0004576	oligosaccharyl transferase activity(GO:0004576) dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.1	0.7	GO:0004691	cAMP-dependent protein kinase activity(GO:0004691)
0.1	0.6	GO:0000253	3-keto sterol reductase activity(GO:0000253)
0.1	1.1	GO:0008429	phosphatidylethanolamine binding(GO:0008429)
0.1	1.0	GO:0015288	porin activity(GO:0015288)
0.1	0.6	GO:0048101	calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117) calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.1	1.2	GO:0016846	carbon-sulfur lyase activity(GO:0016846)
0.1	2.8	GO:1900750	glutathione binding(GO:0043295) oligopeptide binding(GO:1900750)
0.1	0.7	GO:0004957	prostaglandin E receptor activity(GO:0004957)
0.1	1.9	GO:0005247	voltage-gated chloride channel activity(GO:0005247)
0.1	1.1	GO:0097322	7SK snRNA binding(GO:0097322)
0.1	0.5	GO:0004974	leukotriene receptor activity(GO:0004974)
0.1	0.9	GO:0008889	glycerophosphodiester phosphodiesterase activity(GO:0008889)
0.1	0.4	GO:0018271	biotin-[acetyl-CoA-carboxylase] ligase activity(GO:0004077) biotin-[methylcrotonoyl-CoA-carboxylase] ligase activity(GO:0004078) biotin-[methylmalonyl-CoA-carboxytransferase] ligase activity(GO:0004079) biotin-[propionyl-CoA-carboxylase (ATP-hydrolyzing)] ligase activity(GO:0004080) biotin-protein ligase activity(GO:0018271)
0.1	1.0	GO:0031681	G-protein beta-subunit binding(GO:0031681)
0.1	2.7	GO:0005355	glucose transmembrane transporter activity(GO:0005355)
0.1	1.9	GO:0004653	polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.1	0.4	GO:0016907	G-protein coupled acetylcholine receptor activity(GO:0016907)
0.1	3.5	GO:0005086	ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.1	1.1	GO:0004571	mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.1	1.7	GO:0097371	MDM2/MDM4 family protein binding(GO:0097371)
0.1	8.4	GO:0004869	cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.1	2.2	GO:0035259	glucocorticoid receptor binding(GO:0035259)
0.1	1.6	GO:0070410	co-SMAD binding(GO:0070410)
0.1	1.3	GO:0005078	MAP-kinase scaffold activity(GO:0005078) mitogen-activated protein kinase p38 binding(GO:0048273)
0.1	2.2	GO:0004190	aspartic-type endopeptidase activity(GO:0004190)
0.1	0.9	GO:0102391	long-chain fatty acid-CoA ligase activity(GO:0004467) decanoate--CoA ligase activity(GO:0102391)
0.1	2.5	GO:0017134	fibroblast growth factor binding(GO:0017134)
0.1	1.3	GO:0004115	3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.1	7.9	GO:0019905	syntaxin binding(GO:0019905)
0.1	4.2	GO:0015485	cholesterol binding(GO:0015485)
0.1	0.4	GO:0045322	unmethylated CpG binding(GO:0045322)
0.1	2.8	GO:0003899	DNA-directed RNA polymerase activity(GO:0003899)
0.1	1.3	GO:0015269	calcium-activated potassium channel activity(GO:0015269)
0.1	0.4	GO:0072542	protein phosphatase activator activity(GO:0072542)
0.1	3.8	GO:0001965	G-protein alpha-subunit binding(GO:0001965)
0.1	0.4	GO:0031849	olfactory receptor binding(GO:0031849)
0.1	7.7	GO:0015293	symporter activity(GO:0015293)
0.1	8.4	GO:0004867	serine-type endopeptidase inhibitor activity(GO:0004867)
0.1	1.4	GO:0000400	four-way junction DNA binding(GO:0000400)
0.1	1.2	GO:0044548	S100 protein binding(GO:0044548)
0.1	0.4	GO:0071532	ankyrin repeat binding(GO:0071532)
0.1	2.1	GO:0008157	protein phosphatase 1 binding(GO:0008157)
0.1	0.5	GO:0016861	intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.0	4.4	GO:0035591	signaling adaptor activity(GO:0035591)
0.0	0.5	GO:0044323	retinoic acid-responsive element binding(GO:0044323)
0.0	0.8	GO:0016780	phosphotransferase activity, for other substituted phosphate groups(GO:0016780)
0.0	2.1	GO:0005507	copper ion binding(GO:0005507)
0.0	4.0	GO:0003707	steroid hormone receptor activity(GO:0003707)
0.0	0.3	GO:0004706	JUN kinase kinase kinase activity(GO:0004706)
0.0	0.1	GO:0004958	prostaglandin F receptor activity(GO:0004958)
0.0	0.4	GO:0030306	ADP-ribosylation factor binding(GO:0030306)
0.0	1.3	GO:0005521	lamin binding(GO:0005521)
0.0	0.2	GO:0016499	orexin receptor activity(GO:0016499)
0.0	1.7	GO:0030676	Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0	2.3	GO:0017112	Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0	0.4	GO:0008020	G-protein coupled photoreceptor activity(GO:0008020)
0.0	0.5	GO:0038062	protein tyrosine kinase collagen receptor activity(GO:0038062)
0.0	0.5	GO:0016888	endodeoxyribonuclease activity, producing 5'-phosphomonoesters(GO:0016888)
0.0	0.2	GO:0070728	leucine binding(GO:0070728)
0.0	2.0	GO:0061631	ubiquitin conjugating enzyme activity(GO:0061631)
0.0	1.1	GO:0031489	myosin V binding(GO:0031489)
0.0	1.1	GO:0005251	delayed rectifier potassium channel activity(GO:0005251)
0.0	0.1	GO:0004947	bradykinin receptor activity(GO:0004947)
0.0	0.5	GO:0019911	structural constituent of myelin sheath(GO:0019911)
0.0	0.3	GO:0005375	copper ion transmembrane transporter activity(GO:0005375)
0.0	0.4	GO:0005001	transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0	0.8	GO:0017128	phospholipid scramblase activity(GO:0017128)
0.0	2.7	GO:0035064	methylated histone binding(GO:0035064)
0.0	0.8	GO:0005212	structural constituent of eye lens(GO:0005212)
0.0	0.3	GO:0001162	RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding(GO:0001162)
0.0	1.7	GO:0001784	phosphotyrosine binding(GO:0001784)
0.0	0.9	GO:0043014	alpha-tubulin binding(GO:0043014)
0.0	0.2	GO:0001594	trace-amine receptor activity(GO:0001594)
0.0	0.2	GO:0001640	adenylate cyclase inhibiting G-protein coupled glutamate receptor activity(GO:0001640)
0.0	0.3	GO:0031434	mitogen-activated protein kinase kinase binding(GO:0031434)
0.0	0.3	GO:0030550	acetylcholine receptor inhibitor activity(GO:0030550)
0.0	0.6	GO:0005246	calcium channel regulator activity(GO:0005246)
0.0	0.6	GO:0004623	phospholipase A2 activity(GO:0004623)
0.0	1.5	GO:0019003	GDP binding(GO:0019003)
0.0	1.9	GO:0098811	transcriptional activator activity, RNA polymerase II transcription factor binding(GO:0001190) transcriptional repressor activity, RNA polymerase II activating transcription factor binding(GO:0098811)
0.0	0.1	GO:0016868	intramolecular transferase activity, phosphotransferases(GO:0016868)
0.0	0.4	GO:0016805	dipeptidase activity(GO:0016805)
0.0	0.4	GO:0042166	acetylcholine binding(GO:0042166)
0.0	0.2	GO:0005338	nucleotide-sugar transmembrane transporter activity(GO:0005338)
0.0	0.2	GO:0017081	chloride channel regulator activity(GO:0017081)
0.0	0.3	GO:0038191	neuropilin binding(GO:0038191)
0.0	0.1	GO:0008493	tetracycline transporter activity(GO:0008493)
0.0	0.7	GO:0004012	phospholipid-translocating ATPase activity(GO:0004012)
0.0	2.0	GO:0003727	single-stranded RNA binding(GO:0003727)
0.0	1.9	GO:0004860	protein kinase inhibitor activity(GO:0004860)
0.0	2.2	GO:0005262	calcium channel activity(GO:0005262)
0.0	0.6	GO:0001221	transcription cofactor binding(GO:0001221)
0.0	4.2	GO:0003714	transcription corepressor activity(GO:0003714)
0.0	0.4	GO:0004993	G-protein coupled serotonin receptor activity(GO:0004993)
0.0	1.3	GO:0016298	lipase activity(GO:0016298)
0.0	0.5	GO:0030331	estrogen receptor binding(GO:0030331)
0.0	0.1	GO:0046974	histone methyltransferase activity (H3-K9 specific)(GO:0046974)
0.0	1.7	GO:0034987	immunoglobulin receptor binding(GO:0034987)
0.0	0.3	GO:0003841	1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.0	0.4	GO:0005104	fibroblast growth factor receptor binding(GO:0005104)
0.0	0.4	GO:0005184	neuropeptide hormone activity(GO:0005184)
0.0	0.3	GO:0048487	beta-tubulin binding(GO:0048487)
0.0	0.3	GO:0004890	GABA-A receptor activity(GO:0004890)
0.0	0.6	GO:0016706	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors(GO:0016706)
0.0	3.2	GO:0061659	ubiquitin protein ligase activity(GO:0061630) ubiquitin-like protein ligase activity(GO:0061659)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.7	24.0	ST WNT CA2 CYCLIC GMP PATHWAY	Wnt/Ca2+/cyclic GMP signaling.
0.4	7.3	PID ERB GENOMIC PATHWAY	Validated nuclear estrogen receptor beta network
0.3	7.7	PID THROMBIN PAR4 PATHWAY	PAR4-mediated thrombin signaling events
0.2	15.7	PID HNF3B PATHWAY	FOXA2 and FOXA3 transcription factor networks
0.2	0.4	PID RANBP2 PATHWAY	Sumoylation by RanBP2 regulates transcriptional repression
0.2	14.7	PID A6B1 A6B4 INTEGRIN PATHWAY	a6b1 and a6b4 Integrin signaling
0.2	8.5	PID TCR CALCIUM PATHWAY	Calcium signaling in the CD4+ TCR pathway
0.1	2.2	PID AJDISS 2PATHWAY	Posttranslational regulation of adherens junction stability and dissassembly
0.1	1.2	PID VEGF VEGFR PATHWAY	VEGF and VEGFR signaling network
0.1	1.4	PID IL5 PATHWAY	IL5-mediated signaling events
0.1	20.8	NABA ECM AFFILIATED	Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.1	3.0	PID ARF6 DOWNSTREAM PATHWAY	Arf6 downstream pathway
0.1	2.3	PID ATF2 PATHWAY	ATF-2 transcription factor network
0.1	6.5	PID HDAC CLASSII PATHWAY	Signaling events mediated by HDAC Class II
0.1	0.5	ST JAK STAT PATHWAY	Jak-STAT Pathway
0.1	0.8	PID ERBB NETWORK PATHWAY	ErbB receptor signaling network
0.1	1.9	PID FRA PATHWAY	Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.1	9.2	WNT SIGNALING	Genes related to Wnt-mediated signal transduction
0.1	4.1	PID IL6 7 PATHWAY	IL6-mediated signaling events
0.1	3.6	PID ARF6 TRAFFICKING PATHWAY	Arf6 trafficking events
0.1	1.7	ST TUMOR NECROSIS FACTOR PATHWAY	Tumor Necrosis Factor Pathway.
0.1	1.2	PID LPA4 PATHWAY	LPA4-mediated signaling events
0.1	3.2	PID DELTA NP63 PATHWAY	Validated transcriptional targets of deltaNp63 isoforms
0.1	2.0	PID IL23 PATHWAY	IL23-mediated signaling events
0.1	0.8	PID VEGFR1 2 PATHWAY	Signaling events mediated by VEGFR1 and VEGFR2
0.1	4.8	PID CASPASE PATHWAY	Caspase cascade in apoptosis
0.0	2.9	PID REG GR PATHWAY	Glucocorticoid receptor regulatory network
0.0	1.3	PID RHODOPSIN PATHWAY	Visual signal transduction: Rods
0.0	0.8	PID GLYPICAN 1PATHWAY	Glypican 1 network
0.0	12.4	NABA ECM REGULATORS	Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0	3.9	PID CMYB PATHWAY	C-MYB transcription factor network
0.0	1.7	PID ENDOTHELIN PATHWAY	Endothelins
0.0	0.4	PID ALK2 PATHWAY	ALK2 signaling events
0.0	1.1	PID RXR VDR PATHWAY	RXR and RAR heterodimerization with other nuclear receptor
0.0	1.4	PID NFAT TFPATHWAY	Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0	2.7	PID RHOA REG PATHWAY	Regulation of RhoA activity
0.0	0.9	PID TCPTP PATHWAY	Signaling events mediated by TCPTP
0.0	1.9	PID FCER1 PATHWAY	Fc-epsilon receptor I signaling in mast cells
0.0	1.8	PID CDC42 REG PATHWAY	Regulation of CDC42 activity
0.0	1.0	PID AR TF PATHWAY	Regulation of Androgen receptor activity
0.0	1.2	PID INTEGRIN3 PATHWAY	Beta3 integrin cell surface interactions
0.0	0.9	PID ECADHERIN NASCENT AJ PATHWAY	E-cadherin signaling in the nascent adherens junction
0.0	1.1	PID HEDGEHOG GLI PATHWAY	Hedgehog signaling events mediated by Gli proteins
0.0	0.3	PID IFNG PATHWAY	IFN-gamma pathway
0.0	0.5	PID KIT PATHWAY	Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0	0.7	PID IL4 2PATHWAY	IL4-mediated signaling events
0.0	0.3	PID ERBB2 ERBB3 PATHWAY	ErbB2/ErbB3 signaling events
0.0	1.2	PID TRKR PATHWAY	Neurotrophic factor-mediated Trk receptor signaling
0.0	0.3	ST G ALPHA S PATHWAY	G alpha s Pathway
0.0	0.4	PID ALPHA SYNUCLEIN PATHWAY	Alpha-synuclein signaling
0.0	0.3	PID HIF2PATHWAY	HIF-2-alpha transcription factor network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
4.8	96.5	REACTOME HDL MEDIATED LIPID TRANSPORT	Genes involved in HDL-mediated lipid transport
2.0	27.9	REACTOME REGULATION OF COMPLEMENT CASCADE	Genes involved in Regulation of Complement cascade
1.8	51.4	REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION	Genes involved in Amino acid synthesis and interconversion (transamination)
1.6	33.2	REACTOME AMINE DERIVED HORMONES	Genes involved in Amine-derived hormones
1.5	20.8	REACTOME TRYPTOPHAN CATABOLISM	Genes involved in Tryptophan catabolism
1.5	23.4	REACTOME ABACAVIR TRANSPORT AND METABOLISM	Genes involved in Abacavir transport and metabolism
1.4	18.2	REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS	Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
1.4	27.8	REACTOME PYRIMIDINE CATABOLISM	Genes involved in Pyrimidine catabolism
1.4	28.7	REACTOME LIPOPROTEIN METABOLISM	Genes involved in Lipoprotein metabolism
1.1	17.2	REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL	Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
1.1	12.2	REACTOME GLUCURONIDATION	Genes involved in Glucuronidation
1.0	19.7	REACTOME ALPHA LINOLENIC ACID ALA METABOLISM	Genes involved in alpha-linolenic acid (ALA) metabolism
1.0	75.0	REACTOME RESPIRATORY ELECTRON TRANSPORT	Genes involved in Respiratory electron transport
0.9	10.1	REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 7ALPHA HYDROXYCHOLESTEROL	Genes involved in Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol
0.9	10.1	REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT	Genes involved in Organic cation/anion/zwitterion transport
0.7	5.9	REACTOME CREATION OF C4 AND C2 ACTIVATORS	Genes involved in Creation of C4 and C2 activators
0.7	11.2	REACTOME CALNEXIN CALRETICULIN CYCLE	Genes involved in Calnexin/calreticulin cycle
0.6	5.6	REACTOME COMPLEMENT CASCADE	Genes involved in Complement cascade
0.6	6.0	REACTOME PURINE CATABOLISM	Genes involved in Purine catabolism
0.5	6.0	REACTOME COMMON PATHWAY	Genes involved in Common Pathway
0.5	18.0	REACTOME STEROID HORMONES	Genes involved in Steroid hormones
0.4	7.4	REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION	Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.4	9.9	REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE	Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.4	8.2	REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING	Genes involved in Formation of ATP by chemiosmotic coupling
0.4	8.9	REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS	Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.4	0.8	REACTOME REGULATION OF GLUCOKINASE BY GLUCOKINASE REGULATORY PROTEIN	Genes involved in Regulation of Glucokinase by Glucokinase Regulatory Protein
0.4	13.6	REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS	Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.3	28.7	REACTOME METABOLISM OF VITAMINS AND COFACTORS	Genes involved in Metabolism of vitamins and cofactors
0.3	22.0	REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE	Genes involved in Amino acid transport across the plasma membrane
0.3	2.7	REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA	Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.3	4.5	REACTOME METABOLISM OF POLYAMINES	Genes involved in Metabolism of polyamines
0.3	2.6	REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS	Genes involved in Elevation of cytosolic Ca2+ levels
0.2	4.5	REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE	Genes involved in Cytochrome P450 - arranged by substrate type
0.2	2.5	REACTOME COPI MEDIATED TRANSPORT	Genes involved in COPI Mediated Transport
0.2	6.7	REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES	Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.2	0.9	REACTOME INFLUENZA LIFE CYCLE	Genes involved in Influenza Life Cycle
0.2	3.7	REACTOME ACYL CHAIN REMODELLING OF PS	Genes involved in Acyl chain remodelling of PS
0.2	2.6	REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS	Genes involved in Facilitative Na+-independent glucose transporters
0.2	6.2	REACTOME INSULIN RECEPTOR RECYCLING	Genes involved in Insulin receptor recycling
0.2	2.3	REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS	Genes involved in Bile salt and organic anion SLC transporters
0.2	18.1	REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY	Genes involved in Nuclear Receptor transcription pathway
0.2	5.3	REACTOME ENOS ACTIVATION AND REGULATION	Genes involved in eNOS activation and regulation
0.2	3.4	REACTOME PHASE1 FUNCTIONALIZATION OF COMPOUNDS	Genes involved in Phase 1 - Functionalization of compounds
0.2	4.6	REACTOME DCC MEDIATED ATTRACTIVE SIGNALING	Genes involved in DCC mediated attractive signaling
0.1	4.0	REACTOME BASIGIN INTERACTIONS	Genes involved in Basigin interactions
0.1	4.3	REACTOME PROLACTIN RECEPTOR SIGNALING	Genes involved in Prolactin receptor signaling
0.1	2.6	REACTOME INTRINSIC PATHWAY	Genes involved in Intrinsic Pathway
0.1	12.2	REACTOME REGULATION OF INSULIN SECRETION BY GLUCAGON LIKE PEPTIDE1	Genes involved in Regulation of Insulin Secretion by Glucagon-like Peptide-1
0.1	0.4	REACTOME NOTCH HLH TRANSCRIPTION PATHWAY	Genes involved in Notch-HLH transcription pathway
0.1	12.3	REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES	Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.1	10.5	REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION	Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.1	2.7	REACTOME HS GAG DEGRADATION	Genes involved in HS-GAG degradation
0.1	1.2	REACTOME GLUCAGON SIGNALING IN METABOLIC REGULATION	Genes involved in Glucagon signaling in metabolic regulation
0.1	23.1	REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES	Genes involved in Metabolism of amino acids and derivatives
0.1	1.9	REACTOME ACTIVATION OF NF KAPPAB IN B CELLS	Genes involved in Activation of NF-kappaB in B Cells
0.1	1.2	REACTOME VEGF LIGAND RECEPTOR INTERACTIONS	Genes involved in VEGF ligand-receptor interactions
0.1	0.8	REACTOME ACYL CHAIN REMODELLING OF PG	Genes involved in Acyl chain remodelling of PG
0.1	1.8	REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS	Genes involved in Ionotropic activity of Kainate Receptors
0.1	1.3	REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX	Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.1	3.9	REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS	Genes involved in Sphingolipid de novo biosynthesis
0.1	1.3	REACTOME EICOSANOID LIGAND BINDING RECEPTORS	Genes involved in Eicosanoid ligand-binding receptors
0.1	1.4	REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS	Genes involved in Glycogen breakdown (glycogenolysis)
0.1	10.3	REACTOME POTASSIUM CHANNELS	Genes involved in Potassium Channels
0.1	1.7	REACTOME P38MAPK EVENTS	Genes involved in p38MAPK events
0.1	1.5	REACTOME VIRAL MESSENGER RNA SYNTHESIS	Genes involved in Viral Messenger RNA Synthesis
0.1	2.0	REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS	Genes involved in Regulation of gene expression in beta cells
0.1	0.6	REACTOME PLATELET CALCIUM HOMEOSTASIS	Genes involved in Platelet calcium homeostasis
0.1	7.6	REACTOME G ALPHA S SIGNALLING EVENTS	Genes involved in G alpha (s) signalling events
0.1	0.9	REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES	Genes involved in Cytosolic sulfonation of small molecules
0.1	6.8	REACTOME MHC CLASS II ANTIGEN PRESENTATION	Genes involved in MHC class II antigen presentation
0.1	2.8	REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES	Genes involved in Chemokine receptors bind chemokines
0.1	1.2	REACTOME PECAM1 INTERACTIONS	Genes involved in PECAM1 interactions
0.1	2.1	REACTOME TIGHT JUNCTION INTERACTIONS	Genes involved in Tight junction interactions
0.1	0.9	REACTOME IL 7 SIGNALING	Genes involved in Interleukin-7 signaling
0.0	2.1	REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S	Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0	2.0	REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS	Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0	0.4	REACTOME OPSINS	Genes involved in Opsins
0.0	0.6	REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS	Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.0	0.8	REACTOME NUCLEOTIDE LIKE PURINERGIC RECEPTORS	Genes involved in Nucleotide-like (purinergic) receptors
0.0	1.1	REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY	Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0	1.3	REACTOME SPHINGOLIPID METABOLISM	Genes involved in Sphingolipid metabolism
0.0	1.1	REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN	Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.0	0.4	REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS	Genes involved in Presynaptic nicotinic acetylcholine receptors
0.0	0.9	REACTOME NUCLEAR SIGNALING BY ERBB4	Genes involved in Nuclear signaling by ERBB4
0.0	0.3	REACTOME SPRY REGULATION OF FGF SIGNALING	Genes involved in Spry regulation of FGF signaling
0.0	0.6	REACTOME CHOLESTEROL BIOSYNTHESIS	Genes involved in Cholesterol biosynthesis
0.0	0.4	REACTOME FGFR4 LIGAND BINDING AND ACTIVATION	Genes involved in FGFR4 ligand binding and activation
0.0	0.4	REACTOME LIPID DIGESTION MOBILIZATION AND TRANSPORT	Genes involved in Lipid digestion, mobilization, and transport
0.0	0.2	REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS	Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.0	1.2	REACTOME RNA POL I RNA POL III AND MITOCHONDRIAL TRANSCRIPTION	Genes involved in RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription
0.0	1.8	REACTOME PEPTIDE LIGAND BINDING RECEPTORS	Genes involved in Peptide ligand-binding receptors
0.0	1.5	REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2	Genes involved in Response to elevated platelet cytosolic Ca2+
0.0	1.0	REACTOME STRIATED MUSCLE CONTRACTION	Genes involved in Striated Muscle Contraction
0.0	1.0	REACTOME G ALPHA I SIGNALLING EVENTS	Genes involved in G alpha (i) signalling events
0.0	0.4	REACTOME OTHER SEMAPHORIN INTERACTIONS	Genes involved in Other semaphorin interactions
0.0	0.3	REACTOME INSULIN SYNTHESIS AND PROCESSING	Genes involved in Insulin Synthesis and Processing
0.0	0.3	REACTOME GROWTH HORMONE RECEPTOR SIGNALING	Genes involved in Growth hormone receptor signaling
0.0	0.3	REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI	Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0	0.1	REACTOME RECYCLING OF BILE ACIDS AND SALTS	Genes involved in Recycling of bile acids and salts
0.0	0.8	REACTOME MYOGENESIS	Genes involved in Myogenesis
0.0	1.7	REACTOME FATTY ACID TRIACYLGLYCEROL AND KETONE BODY METABOLISM	Genes involved in Fatty acid, triacylglycerol, and ketone body metabolism
0.0	0.3	REACTOME GABA RECEPTOR ACTIVATION	Genes involved in GABA receptor activation
0.0	0.6	REACTOME INTEGRATION OF ENERGY METABOLISM	Genes involved in Integration of energy metabolism

Results for Nr2f1_Nr4a1

Z-value: 1.90

Motif logo

Transcription factors associated with Nr2f1_Nr4a1

Activity-expression correlation:

Activity profile of Nr2f1_Nr4a1 motif

Sorted Z-values of Nr2f1_Nr4a1 motif

Top targets:

Network of associatons between targets according to the STRING database.

First level regulatory network of Nr2f1_Nr4a1

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: