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GSE58827: Dynamics of the Mouse Liver

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Results for Nr4a3

Z-value: 0.78

Motif logo

Transcription factors associated with Nr4a3

Gene Symbol Gene ID Gene Info
ENSMUSG00000028341.10 nuclear receptor subfamily 4, group A, member 3

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Nr4a3mm39_v1_chr4_+_48045143_480451600.134.5e-01Click!

Activity profile of Nr4a3 motif

Sorted Z-values of Nr4a3 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr19_+_10019023 2.03 ENSMUST00000237672.2
fatty acid desaturase 3
chr12_-_110945415 1.91 ENSMUST00000135131.2
ENSMUST00000043459.13
ENSMUST00000128353.8
ankyrin repeat domain 9
chr8_-_124621483 1.89 ENSMUST00000034453.6
ENSMUST00000212584.2
actin, alpha 1, skeletal muscle
chrX_-_149372840 1.88 ENSMUST00000112725.8
ENSMUST00000112720.8
apurinic/apyrimidinic endonuclease 2
chr4_+_131600918 1.75 ENSMUST00000053819.6
serine and arginine-rich splicing factor 4
chr6_+_113508636 1.63 ENSMUST00000036340.12
ENSMUST00000204827.3
Fanconi anemia, complementation group D2
chr15_-_78449172 1.49 ENSMUST00000230952.2
Rac family small GTPase 2
chr17_+_47905553 1.40 ENSMUST00000182846.3
cyclin D3
chr12_-_110945052 1.36 ENSMUST00000140788.8
ankyrin repeat domain 9
chr11_+_70548022 1.34 ENSMUST00000157027.8
ENSMUST00000072841.12
ENSMUST00000108548.8
ENSMUST00000126241.8
enolase 3, beta muscle
chr8_+_95722289 1.34 ENSMUST00000211984.2
adhesion G protein-coupled receptor G1
chr12_-_110945376 1.31 ENSMUST00000142012.2
ankyrin repeat domain 9
chr2_-_13496624 1.28 ENSMUST00000091436.7
cubilin (intrinsic factor-cobalamin receptor)
chr3_+_5815863 1.28 ENSMUST00000192045.2
predicted pseudogene 8797
chr7_-_127805518 1.28 ENSMUST00000033049.9
cytochrome c oxidase subunit 6A2
chr7_+_110368037 1.26 ENSMUST00000213373.2
adenosine monophosphate deaminase 3
chr2_+_164647002 1.19 ENSMUST00000052107.5
zinc finger SWIM-type containing 3
chr3_-_104725853 1.16 ENSMUST00000106775.8
ENSMUST00000166979.8
Mov10 RISC complex RNA helicase
chr11_+_113510135 1.15 ENSMUST00000146390.3
somatostatin receptor 2
chr14_-_54655079 1.12 ENSMUST00000226753.2
ENSMUST00000197440.5
solute carrier family 7 (cationic amino acid transporter, y+ system), member 7
chr1_-_152262425 1.11 ENSMUST00000015124.15
tRNA splicing endonuclease subunit 15
chr6_-_76474767 1.05 ENSMUST00000097218.7
predicted pseudogene 9008
chr3_-_104725581 1.04 ENSMUST00000168015.8
Mov10 RISC complex RNA helicase
chr11_-_61384998 1.04 ENSMUST00000101085.9
ENSMUST00000079080.13
ENSMUST00000108714.2
mitogen-activated protein kinase 7
chr14_-_70414236 1.02 ENSMUST00000153735.8
PDZ and LIM domain 2
chr3_-_104725535 1.01 ENSMUST00000002297.12
Mov10 RISC complex RNA helicase
chr19_-_7218363 0.99 ENSMUST00000236769.2
N(alpha)-acetyltransferase 40, NatD catalytic subunit
chr11_+_70548622 0.99 ENSMUST00000170716.8
enolase 3, beta muscle
chr4_-_43578823 0.96 ENSMUST00000030189.14
glucosidase beta 2
chrX_+_74425990 0.94 ENSMUST00000033541.5
FUN14 domain containing 2
chr1_-_152262339 0.94 ENSMUST00000162371.2
tRNA splicing endonuclease subunit 15
chr2_-_167334746 0.89 ENSMUST00000109211.9
ENSMUST00000057627.16
spermatogenesis associated 2
chr7_+_125202653 0.89 ENSMUST00000206103.2
ENSMUST00000033000.8
interleukin 21 receptor
chr11_+_113510207 0.87 ENSMUST00000106630.2
somatostatin receptor 2
chr12_-_111638722 0.82 ENSMUST00000001304.9
creatine kinase, brain
chr12_-_112640626 0.79 ENSMUST00000001780.10
thymoma viral proto-oncogene 1
chr2_-_165125519 0.79 ENSMUST00000155289.8
solute carrier family 35, member C2
chr11_-_3454766 0.75 ENSMUST00000044507.12
inositol polyphosphate 5-phosphatase J
chr1_+_57884693 0.75 ENSMUST00000169772.3
spermatogenesis associated, serine-rich 2-like
chr15_+_79025523 0.70 ENSMUST00000040077.8
polymerase (RNA) II (DNA directed) polypeptide F
chr10_+_79552421 0.69 ENSMUST00000099513.8
ENSMUST00000020581.3
hyperpolarization-activated, cyclic nucleotide-gated K+ 2
chr16_-_4340920 0.68 ENSMUST00000090500.10
ENSMUST00000023161.8
sarcalumenin
chrX_+_55493325 0.67 ENSMUST00000079663.7
predicted gene 2174
chr3_-_95041246 0.67 ENSMUST00000172572.9
ENSMUST00000173462.3
sodium channel modifier 1
chr5_+_34527230 0.62 ENSMUST00000180376.8
family with sequence homology 193, member A
chr4_+_43578922 0.59 ENSMUST00000030190.9
RAB6A GEF compex partner 1
chr4_+_125952349 0.58 ENSMUST00000035497.5
ENSMUST00000143712.3
organic solute carrier partner 1
chr7_-_28297565 0.57 ENSMUST00000040531.9
ENSMUST00000108283.8
sterile alpha motif domain containing 4B
p21 (RAC1) activated kinase 4
chr3_+_101993787 0.56 ENSMUST00000165540.9
ENSMUST00000164123.2
calsequestrin 2
chr1_+_75412574 0.55 ENSMUST00000037796.14
ENSMUST00000113584.8
ENSMUST00000145166.8
ENSMUST00000143730.8
ENSMUST00000133418.8
ENSMUST00000144874.8
ENSMUST00000140287.8
GDP-mannose pyrophosphorylase A
chr12_-_112640378 0.54 ENSMUST00000130342.2
thymoma viral proto-oncogene 1
chr15_+_84553801 0.54 ENSMUST00000171460.8
proline rich 5 (renal)
chr7_-_79115915 0.53 ENSMUST00000073889.14
polymerase (DNA directed), gamma
chr8_-_121394742 0.53 ENSMUST00000181334.2
ENSMUST00000181950.2
ENSMUST00000181333.2
ER membrane protein complex subunit 8
predicted gene, 27021
chr7_-_79115760 0.53 ENSMUST00000125562.2
polymerase (DNA directed), gamma
chr15_-_79688910 0.51 ENSMUST00000175858.10
ENSMUST00000023057.10
neuronal pentraxin receptor
chr4_+_130297132 0.50 ENSMUST00000105993.4
Na+/K+ transporting ATPase interacting 1
chr10_-_80184238 0.49 ENSMUST00000095446.10
ENSMUST00000105352.2
ADAMTS-like 5
chr8_+_120588977 0.49 ENSMUST00000034287.10
kelch-like 36
chr2_-_163259012 0.49 ENSMUST00000127038.2
oxidative stress responsive serine rich 1
chr4_-_152213315 0.47 ENSMUST00000049305.14
espin
chr15_-_76606361 0.46 ENSMUST00000049956.5
leucine rich repeat containing 24
chr4_-_138858340 0.46 ENSMUST00000143971.2
mitochondrial contact site and cristae organizing system subunit 10
chr19_-_40371016 0.45 ENSMUST00000225766.3
sorbin and SH3 domain containing 1
chr13_+_73476629 0.45 ENSMUST00000221730.2
mitochondrial ribosomal protein L36
chr2_+_158636727 0.45 ENSMUST00000029186.14
ENSMUST00000109478.9
ENSMUST00000156893.2
DEAH (Asp-Glu-Ala-His) box polypeptide 35
chr15_-_102425241 0.45 ENSMUST00000169162.8
ENSMUST00000023812.10
ENSMUST00000165174.8
ENSMUST00000169367.8
ENSMUST00000169377.8
mitogen-activated protein kinase kinase kinase 12
chr17_-_36220924 0.45 ENSMUST00000141662.8
ENSMUST00000056034.13
ENSMUST00000077494.13
ENSMUST00000149277.8
ENSMUST00000061052.12
alpha tubulin acetyltransferase 1
chr4_-_41697040 0.44 ENSMUST00000102962.10
ciliary neurotrophic factor receptor
chr17_+_29579882 0.44 ENSMUST00000024810.8
FYVE, RhoGEF and PH domain containing 2
chr2_-_164646794 0.43 ENSMUST00000103094.11
ENSMUST00000017451.7
acyl-CoA thioesterase 8
chr10_+_59239466 0.43 ENSMUST00000009790.14
phospholipase A2, group XIIB
chr14_-_52252318 0.42 ENSMUST00000228051.2
zinc finger protein 219
chr13_-_73476561 0.38 ENSMUST00000222930.2
ENSMUST00000223293.2
ENSMUST00000022097.6
NADH:ubiquinone oxidoreductase core subunit S6
chr15_-_63932288 0.37 ENSMUST00000063838.11
ENSMUST00000228908.2
CYFIP related Rac1 interactor B
chr14_-_52252432 0.37 ENSMUST00000226527.2
zinc finger protein 219
chr19_+_46140942 0.35 ENSMUST00000026254.14
golgi-specific brefeldin A-resistance factor 1
chr19_+_37184927 0.35 ENSMUST00000024078.15
ENSMUST00000112391.8
membrane associated ring-CH-type finger 5
chr14_-_52252003 0.35 ENSMUST00000226522.2
zinc finger protein 219
chr5_+_67125902 0.33 ENSMUST00000127184.8
LIM and calponin homology domains 1
chr12_-_84240781 0.31 ENSMUST00000110294.2
mitotic deacetylase associated SANT domain protein
chr2_+_157120946 0.31 ENSMUST00000116380.9
ENSMUST00000029171.6
ribophorin II
chr11_+_115366470 0.30 ENSMUST00000035240.7
armadillo repeat containing 7
chr4_+_115932466 0.30 ENSMUST00000030471.9
leucine rich repeat containing 41
chr14_-_21898992 0.29 ENSMUST00000124549.9
catechol-O-methyltransferase domain containing 1
chr17_-_36220518 0.28 ENSMUST00000141132.2
alpha tubulin acetyltransferase 1
chr1_+_36730530 0.28 ENSMUST00000081180.7
ENSMUST00000193210.6
ENSMUST00000195151.6
cytochrome c oxidase subunit 5B
chr9_-_110818679 0.28 ENSMUST00000084922.6
ENSMUST00000199891.2
receptor transporter protein 3
chr8_-_121394860 0.27 ENSMUST00000034277.14
ER membrane protein complex subunit 8
chr19_-_45986919 0.27 ENSMUST00000045396.9
armadillo-like helical domain containing 3
chr5_-_132572181 0.26 ENSMUST00000161226.11
autism susceptibility candidate 2
chr2_-_157121440 0.26 ENSMUST00000143663.2
maestro heat-like repeat family member 8
chr19_-_37184692 0.26 ENSMUST00000132580.8
ENSMUST00000079754.11
ENSMUST00000136286.8
ENSMUST00000126188.8
ENSMUST00000126781.2
cytoplasmic polyadenylation element binding protein 3
chr6_+_41523664 0.25 ENSMUST00000103299.3
T cell receptor beta, constant 2
chr6_+_124986627 0.25 ENSMUST00000046064.17
ENSMUST00000152752.8
ENSMUST00000088308.10
ENSMUST00000112425.8
ENSMUST00000084275.12
zinc finger protein 384
chr15_-_63932176 0.25 ENSMUST00000226675.2
ENSMUST00000228226.2
ENSMUST00000227024.2
CYFIP related Rac1 interactor B
chr10_-_23226684 0.24 ENSMUST00000220299.2
EYA transcriptional coactivator and phosphatase 4
chr8_-_105350533 0.24 ENSMUST00000212662.2
cadherin 16
chr6_-_137548004 0.24 ENSMUST00000100841.9
epidermal growth factor receptor pathway substrate 8
chr8_-_22550035 0.24 ENSMUST00000110738.3
ATPase, Cu++ transporting, beta polypeptide
chr1_-_160079007 0.24 ENSMUST00000191909.6
RAB GTPase activating protein 1-like
chr19_-_56996617 0.23 ENSMUST00000118800.8
ENSMUST00000111584.9
ENSMUST00000122359.8
ENSMUST00000148049.8
actin filament associated protein 1-like 2
chr19_-_7194912 0.22 ENSMUST00000039758.6
cytochrome c oxidase subunit 8A
chrX_-_70536449 0.20 ENSMUST00000037391.12
ENSMUST00000114586.9
ENSMUST00000114587.3
CD99 antigen-like 2
chr7_+_45546365 0.20 ENSMUST00000069772.16
ENSMUST00000210503.2
ENSMUST00000209350.2
transmembrane protein 143
chrX_+_149372903 0.19 ENSMUST00000080884.11
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1
chr2_+_69500444 0.19 ENSMUST00000100050.4
kelch-like 41
chr11_-_99134885 0.18 ENSMUST00000103132.10
ENSMUST00000038214.7
keratin 222
chr3_-_59038634 0.18 ENSMUST00000200358.2
ENSMUST00000197220.2
purinergic receptor P2Y, G-protein coupled, 14
chr1_+_181180183 0.18 ENSMUST00000161880.8
ENSMUST00000027795.14
cornichon family AMPA receptor auxiliary protein 3
chr11_-_115158062 0.17 ENSMUST00000106554.2
glutamate receptor, ionotropic, NMDA2C (epsilon 3)
chr8_-_105350842 0.17 ENSMUST00000212324.2
cadherin 16
chr11_-_100713348 0.16 ENSMUST00000107358.9
signal transducer and activator of transcription 5B
chr17_-_27842237 0.16 ENSMUST00000062397.13
ENSMUST00000176876.8
ENSMUST00000146321.3
nudix (nucleotide diphosphate linked moiety X)-type motif 3
chr10_-_20600442 0.15 ENSMUST00000170265.8
phosphodiesterase 7B
chr7_-_126074256 0.15 ENSMUST00000205440.2
ENSMUST00000032978.8
ENSMUST00000205340.2
SH2B adaptor protein 1
chr11_-_4654303 0.15 ENSMUST00000058407.6
ubiquinol-cytochrome c reductase, complex III subunit X
chr4_+_99786611 0.15 ENSMUST00000058351.16
phosphoglucomutase 1
chr1_-_172034354 0.15 ENSMUST00000013842.12
ENSMUST00000111247.8
phosphoprotein enriched in astrocytes 15A
chr13_+_54346116 0.13 ENSMUST00000038101.4
histamine receptor H2
chr8_-_105350816 0.13 ENSMUST00000212447.2
cadherin 16
chr3_-_89121147 0.13 ENSMUST00000173477.8
ENSMUST00000119222.9
metaxin 1
chrX_-_70536198 0.12 ENSMUST00000080035.11
CD99 antigen-like 2
chr6_-_138403732 0.12 ENSMUST00000162932.2
LIM domain only 3
chr5_+_16758897 0.11 ENSMUST00000196645.2
hepatocyte growth factor
chr4_+_99812912 0.11 ENSMUST00000102783.5
phosphoglucomutase 1
chr9_+_21914513 0.11 ENSMUST00000215795.2
protein kinase C substrate 80K-H
chr5_-_23881353 0.11 ENSMUST00000198661.5
serine/arginine-rich protein specific kinase 2
chr3_-_59038539 0.10 ENSMUST00000198838.2
purinergic receptor P2Y, G-protein coupled, 14
chr16_+_4704166 0.10 ENSMUST00000230990.2
mahogunin, ring finger 1
chr14_+_53073315 0.10 ENSMUST00000197128.2
T cell receptor alpha variable 7D-5
chr5_+_67125759 0.10 ENSMUST00000238993.2
ENSMUST00000038188.14
LIM and calponin homology domains 1
chr16_+_4704103 0.10 ENSMUST00000023159.10
ENSMUST00000070658.16
ENSMUST00000229038.2
mahogunin, ring finger 1
chr4_-_126096376 0.08 ENSMUST00000106142.8
ENSMUST00000169403.8
ENSMUST00000130334.2
thyroid hormone receptor associated protein 3
chr14_+_53007210 0.07 ENSMUST00000178768.4
T cell receptor alpha variable 7D-4
chr8_-_105350898 0.07 ENSMUST00000212882.2
ENSMUST00000163783.4
cadherin 16
chr11_-_105346120 0.07 ENSMUST00000138977.8
membrane associated ring-CH-type finger 10
chr8_-_105350881 0.07 ENSMUST00000211903.2
cadherin 16
chr8_+_125519751 0.07 ENSMUST00000041106.9
ENSMUST00000167588.9
tripartite motif-containing 67
chr4_+_106479624 0.06 ENSMUST00000047922.3
tetratricopeptide repeat domain 22
chr8_-_32440071 0.06 ENSMUST00000207678.3
neuregulin 1
chr15_-_79025387 0.05 ENSMUST00000187550.7
ENSMUST00000188562.7
ENSMUST00000190509.7
ENSMUST00000190730.7
ENSMUST00000190959.7
ENSMUST00000169604.8
ENSMUST00000186053.7
RIKEN cDNA 1700088E04 gene
chrX_-_46981379 0.04 ENSMUST00000077569.11
ENSMUST00000101616.9
ENSMUST00000088973.11
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1
chr2_+_79538124 0.04 ENSMUST00000090760.9
ENSMUST00000040863.11
ENSMUST00000111780.3
protein phosphatase 1, regulatory inhibitor subunit 1C
chr9_-_80347482 0.04 ENSMUST00000085289.12
ENSMUST00000185068.2
ENSMUST00000113250.10
interphotoreceptor matrix proteoglycan 1
chr11_+_90528953 0.04 ENSMUST00000020851.15
cytochrome c oxidase assembly protein 11, copper chaperone
chr15_+_100659622 0.03 ENSMUST00000023776.13
solute carrier family 4 (anion exchanger), member 8
chr5_+_16758777 0.02 ENSMUST00000030683.8
hepatocyte growth factor
chr18_-_60757272 0.02 ENSMUST00000155195.3
synaptopodin
chr9_+_74978429 0.02 ENSMUST00000123128.8
myosin VA
chr9_-_18585826 0.00 ENSMUST00000208663.2
mucin 16
chrX_-_74426221 0.00 ENSMUST00000147349.8
coagulation factor VIII

Network of associatons between targets according to the STRING database.

First level regulatory network of Nr4a3

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 3.2 GO:0098795 mRNA cleavage involved in gene silencing by miRNA(GO:0035279) mRNA cleavage involved in gene silencing(GO:0098795)
0.3 1.0 GO:0070376 regulation of ERK5 cascade(GO:0070376)
0.3 1.3 GO:0060709 glycogen cell differentiation involved in embryonic placenta development(GO:0060709)
0.2 0.7 GO:0071929 alpha-tubulin acetylation(GO:0071929)
0.2 1.3 GO:0015889 cobalamin transport(GO:0015889)
0.2 0.8 GO:0015786 UDP-glucose transport(GO:0015786)
0.2 1.0 GO:0006680 glucosylceramide catabolic process(GO:0006680)
0.2 0.6 GO:0098749 cerebellar neuron development(GO:0098749)
0.2 1.8 GO:0030240 skeletal muscle thin filament assembly(GO:0030240)
0.2 0.7 GO:0014873 response to muscle activity involved in regulation of muscle adaptation(GO:0014873)
0.2 1.6 GO:2000348 regulation of CD40 signaling pathway(GO:2000348)
0.1 1.5 GO:0060753 regulation of mast cell chemotaxis(GO:0060753)
0.1 2.1 GO:0006388 tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
0.1 1.1 GO:0000821 regulation of arginine metabolic process(GO:0000821)
0.1 2.0 GO:0030432 peristalsis(GO:0030432)
0.1 1.3 GO:0032264 IMP salvage(GO:0032264)
0.1 0.4 GO:0070973 protein localization to endoplasmic reticulum exit site(GO:0070973)
0.1 0.4 GO:0003360 brainstem development(GO:0003360)
0.1 0.7 GO:0071321 cellular response to cGMP(GO:0071321)
0.1 0.3 GO:0002182 cytoplasmic translational elongation(GO:0002182) regulation of cytoplasmic translational elongation(GO:1900247) negative regulation of cytoplasmic translational elongation(GO:1900248)
0.1 1.4 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.1 0.2 GO:0015680 intracellular copper ion transport(GO:0015680)
0.1 0.6 GO:0071313 cellular response to caffeine(GO:0071313)
0.1 0.3 GO:0098582 innate vocalization behavior(GO:0098582)
0.1 0.2 GO:0070358 actin polymerization-dependent cell motility(GO:0070358)
0.1 0.5 GO:0038203 TORC2 signaling(GO:0038203)
0.1 0.5 GO:0030046 parallel actin filament bundle assembly(GO:0030046)
0.1 0.2 GO:0033058 directional locomotion(GO:0033058)
0.1 1.3 GO:0021796 cerebral cortex regionalization(GO:0021796)
0.1 1.1 GO:0006264 mitochondrial DNA replication(GO:0006264)
0.0 0.8 GO:0030644 cellular chloride ion homeostasis(GO:0030644)
0.0 0.4 GO:2000672 negative regulation of motor neuron apoptotic process(GO:2000672)
0.0 0.1 GO:0001698 gastrin-induced gastric acid secretion(GO:0001698)
0.0 1.1 GO:0030213 hyaluronan biosynthetic process(GO:0030213)
0.0 1.8 GO:0048025 negative regulation of mRNA splicing, via spliceosome(GO:0048025)
0.0 0.2 GO:0071544 diphosphoinositol polyphosphate catabolic process(GO:0071544)
0.0 1.9 GO:0006284 base-excision repair(GO:0006284)
0.0 1.0 GO:0043968 N-terminal protein amino acid acetylation(GO:0006474) histone H2A acetylation(GO:0043968)
0.0 0.4 GO:0043649 dicarboxylic acid catabolic process(GO:0043649)
0.0 0.3 GO:0035589 G-protein coupled purinergic nucleotide receptor signaling pathway(GO:0035589)
0.0 0.8 GO:0031115 negative regulation of microtubule polymerization(GO:0031115)
0.0 0.2 GO:0097531 mast cell migration(GO:0097531)
0.0 0.1 GO:0035063 nuclear speck organization(GO:0035063)
0.0 0.2 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.0 0.7 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.0 2.3 GO:0006096 glycolytic process(GO:0006096)
0.0 0.2 GO:0016576 histone dephosphorylation(GO:0016576)
0.0 0.2 GO:0043951 negative regulation of cAMP-mediated signaling(GO:0043951)
0.0 0.3 GO:0045725 positive regulation of glycogen biosynthetic process(GO:0045725)
0.0 0.3 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.0 0.1 GO:0034551 respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551)
0.0 0.2 GO:0031272 regulation of pseudopodium assembly(GO:0031272) regulation of myoblast proliferation(GO:2000291)
0.0 0.4 GO:0050482 arachidonic acid secretion(GO:0050482) arachidonate transport(GO:1903963)
0.0 0.4 GO:0070584 mitochondrion morphogenesis(GO:0070584)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.1 GO:0005760 gamma DNA polymerase complex(GO:0005760)
0.3 1.3 GO:0043202 lysosomal lumen(GO:0043202)
0.2 0.7 GO:0098855 HCN channel complex(GO:0098855)
0.2 0.6 GO:0034066 RIC1-RGP1 guanyl-nucleotide exchange factor complex(GO:0034066)
0.2 0.6 GO:0033018 sarcoplasmic reticulum lumen(GO:0033018)
0.2 2.3 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.1 1.3 GO:0097451 glial limiting end-foot(GO:0097451)
0.1 0.4 GO:0097059 CNTFR-CLCF1 complex(GO:0097059)
0.1 1.4 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.1 0.2 GO:0043540 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex(GO:0043540)
0.1 0.3 GO:0005899 insulin receptor complex(GO:0005899)
0.1 0.7 GO:0097427 microtubule bundle(GO:0097427)
0.1 0.7 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.0 1.8 GO:0005865 striated muscle thin filament(GO:0005865)
0.0 0.5 GO:0031932 TORC2 complex(GO:0031932)
0.0 0.9 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.0 0.5 GO:0043205 microfibril(GO:0001527) fibril(GO:0043205)
0.0 0.3 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.0 3.8 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.0 1.4 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0 0.5 GO:0032426 stereocilium tip(GO:0032426)
0.0 0.3 GO:0030014 CCR4-NOT complex(GO:0030014)
0.0 0.4 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.0 0.4 GO:0031907 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.0 2.8 GO:0001650 fibrillar center(GO:0001650)
0.0 1.0 GO:0005793 endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.9 GO:0008311 double-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008311)
0.3 2.1 GO:0000213 tRNA-intron endonuclease activity(GO:0000213)
0.3 2.0 GO:0004994 somatostatin receptor activity(GO:0004994)
0.3 1.0 GO:0004348 glucosylceramidase activity(GO:0004348)
0.3 0.8 GO:0052658 inositol-1,4,5-trisphosphate 5-phosphatase activity(GO:0052658)
0.2 1.3 GO:0030492 hemoglobin binding(GO:0030492)
0.2 0.5 GO:0001847 opsonin receptor activity(GO:0001847)
0.2 2.3 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.1 1.8 GO:1990825 sequence-specific mRNA binding(GO:1990825)
0.1 1.3 GO:0047623 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.1 0.8 GO:0004111 creatine kinase activity(GO:0004111)
0.1 0.7 GO:0005222 intracellular cAMP activated cation channel activity(GO:0005222)
0.1 1.0 GO:1990189 peptide-serine-N-acetyltransferase activity(GO:1990189)
0.1 1.2 GO:0030235 nitric-oxide synthase regulator activity(GO:0030235)
0.1 0.7 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.1 0.2 GO:0004008 copper-exporting ATPase activity(GO:0004008) copper-transporting ATPase activity(GO:0043682)
0.1 1.6 GO:0070182 DNA polymerase binding(GO:0070182)
0.1 0.7 GO:0001054 RNA polymerase I activity(GO:0001054) RNA polymerase II activity(GO:0001055)
0.1 1.0 GO:0032036 myosin heavy chain binding(GO:0032036)
0.1 1.1 GO:0015174 basic amino acid transmembrane transporter activity(GO:0015174)
0.0 0.4 GO:0004897 ciliary neurotrophic factor receptor activity(GO:0004897)
0.0 1.4 GO:0016676 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 0.3 GO:0004614 phosphoglucomutase activity(GO:0004614)
0.0 1.0 GO:0004707 MAP kinase activity(GO:0004707)
0.0 0.3 GO:0031849 olfactory receptor binding(GO:0031849)
0.0 1.1 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.0 0.3 GO:0004576 oligosaccharyl transferase activity(GO:0004576) dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.0 0.8 GO:0030371 translation repressor activity(GO:0030371)
0.0 1.4 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
0.0 0.2 GO:0000298 endopolyphosphatase activity(GO:0000298) diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) bis(5'-adenosyl)-hexaphosphatase activity(GO:0034431) bis(5'-adenosyl)-pentaphosphatase activity(GO:0034432)
0.0 0.4 GO:0016290 palmitoyl-CoA hydrolase activity(GO:0016290)
0.0 0.2 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873)
0.0 0.1 GO:0004969 histamine receptor activity(GO:0004969)
0.0 0.3 GO:0045294 alpha-catenin binding(GO:0045294)
0.0 3.6 GO:0004386 helicase activity(GO:0004386)
0.0 1.3 GO:0050840 extracellular matrix binding(GO:0050840)
0.0 0.3 GO:0045028 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.0 0.4 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 0.1 GO:0016681 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.0 0.2 GO:0004972 NMDA glutamate receptor activity(GO:0004972)
0.0 0.4 GO:0004623 phospholipase A2 activity(GO:0004623)
0.0 0.6 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 0.2 GO:0030296 protein tyrosine kinase activator activity(GO:0030296)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 2.8 PID IL8 CXCR2 PATHWAY IL8- and CXCR2-mediated signaling events
0.0 1.6 PID ATM PATHWAY ATM pathway
0.0 1.0 ST GA12 PATHWAY G alpha 12 Pathway
0.0 1.9 PID RHOA PATHWAY RhoA signaling pathway
0.0 1.6 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.0 0.4 PID ARF 3PATHWAY Arf1 pathway
0.0 0.6 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.0 0.4 PID P38 ALPHA BETA PATHWAY Regulation of p38-alpha and p38-beta

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.6 REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY Genes involved in Regulation of the Fanconi anemia pathway
0.1 3.2 REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION Genes involved in Pre-NOTCH Transcription and Translation
0.1 1.3 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.1 1.0 REACTOME ERKS ARE INACTIVATED Genes involved in ERKs are inactivated
0.1 2.5 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.1 1.3 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.0 1.5 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0 0.6 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.0 0.7 REACTOME VIRAL MESSENGER RNA SYNTHESIS Genes involved in Viral Messenger RNA Synthesis
0.0 1.8 REACTOME MRNA 3 END PROCESSING Genes involved in mRNA 3'-end processing
0.0 0.4 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
0.0 1.3 REACTOME STEROID HORMONES Genes involved in Steroid hormones
0.0 1.4 REACTOME G1 PHASE Genes involved in G1 Phase
0.0 0.6 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0 1.1 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.0 1.0 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.0 0.4 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 7ALPHA HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol
0.0 0.3 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.0 0.2 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.0 0.8 REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.0 2.0 REACTOME PEPTIDE LIGAND BINDING RECEPTORS Genes involved in Peptide ligand-binding receptors