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GSE58827: Dynamics of the Mouse Liver

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Results for Nrf1

Z-value: 3.58

Motif logo

Transcription factors associated with Nrf1

Gene Symbol Gene ID Gene Info
ENSMUSG00000058440.15 nuclear respiratory factor 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Nrf1mm39_v1_chr6_+_30047968_300480480.676.4e-06Click!

Activity profile of Nrf1 motif

Sorted Z-values of Nrf1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr5_-_134944366 14.56 ENSMUST00000008987.5
claudin 13
chr11_-_11758923 14.33 ENSMUST00000109664.2
ENSMUST00000150714.2
ENSMUST00000047689.11
ENSMUST00000171080.8
ENSMUST00000171938.2
fidgetin-like 1
chr11_-_40624200 13.65 ENSMUST00000020579.9
hyaluronan mediated motility receptor (RHAMM)
chr15_+_103148824 12.50 ENSMUST00000036004.16
ENSMUST00000087351.9
ENSMUST00000231141.2
heterogeneous nuclear ribonucleoprotein A1
chr11_+_50268546 11.33 ENSMUST00000069304.14
ENSMUST00000077817.8
heterogeneous nuclear ribonucleoprotein H1
chr10_-_5755412 10.96 ENSMUST00000019907.8
F-box protein 5
chr8_+_123294740 10.80 ENSMUST00000006760.3
chromatin licensing and DNA replication factor 1
chr15_-_51855073 10.74 ENSMUST00000022927.11
RAD21 cohesin complex component
chr2_+_160487801 10.26 ENSMUST00000109468.3
topoisomerase (DNA) I
chr5_+_107112186 9.85 ENSMUST00000117196.9
ENSMUST00000031221.12
ENSMUST00000076467.13
cell division cycle 7 (S. cerevisiae)
chr9_-_22300409 9.56 ENSMUST00000040912.9
anillin, actin binding protein
chr17_-_46513499 9.44 ENSMUST00000024749.9
polymerase (DNA directed), eta (RAD 30 related)
chr2_+_125514997 9.32 ENSMUST00000164756.4
EP300 interacting inhibitor of differentiation 1
chr15_+_88635852 9.16 ENSMUST00000041297.15
zinc finger, BED type containing 4
chr17_-_48716756 9.12 ENSMUST00000160319.8
ENSMUST00000159535.2
ENSMUST00000078800.13
ENSMUST00000046719.14
ENSMUST00000162460.8
nuclear transcription factor-Y alpha
chr6_-_126916487 9.12 ENSMUST00000144954.5
ENSMUST00000112220.8
ENSMUST00000112221.8
RAD51 associated protein 1
chr11_-_33113071 8.89 ENSMUST00000093201.13
ENSMUST00000101375.5
ENSMUST00000109354.10
ENSMUST00000075641.10
nucleophosmin 1
chr2_-_172212426 8.72 ENSMUST00000109139.8
ENSMUST00000028997.8
ENSMUST00000109140.10
aurora kinase A
chr12_-_110662765 8.70 ENSMUST00000094361.11
heat shock protein 90, alpha (cytosolic), class A member 1
chr2_+_157401998 8.54 ENSMUST00000153739.9
ENSMUST00000173595.2
ENSMUST00000109526.2
ENSMUST00000173839.2
ENSMUST00000173041.8
ENSMUST00000173793.8
ENSMUST00000172487.2
ENSMUST00000088484.6
neuronatin
chr3_+_107803225 8.53 ENSMUST00000172247.8
ENSMUST00000167387.8
glutathione S-transferase, mu 5
chrX_-_8011952 8.37 ENSMUST00000115615.9
ENSMUST00000115616.8
ENSMUST00000115621.9
RNA binding motif (RNP1, RRM) protein 3
chr12_-_110662723 8.24 ENSMUST00000021698.13
heat shock protein 90, alpha (cytosolic), class A member 1
chr3_+_107803563 8.21 ENSMUST00000169365.2
glutathione S-transferase, mu 5
chr3_-_36626101 8.11 ENSMUST00000029270.10
cyclin A2
chr12_-_110662677 8.11 ENSMUST00000124156.8
heat shock protein 90, alpha (cytosolic), class A member 1
chr3_+_107803137 8.01 ENSMUST00000004134.11
glutathione S-transferase, mu 5
chr2_-_156848923 7.86 ENSMUST00000146413.8
ENSMUST00000103129.9
ENSMUST00000103130.8
DSN1 homolog, MIS12 kinetochore complex component
chr15_-_103148239 7.69 ENSMUST00000118152.8
chromobox 5
chr8_-_124709859 7.64 ENSMUST00000075578.7
ATP-binding cassette, sub-family B (MDR/TAP), member 10
chr3_-_68952057 7.50 ENSMUST00000107802.8
tripartite motif-containing 59
chrX_-_149595711 7.45 ENSMUST00000112697.10
MAGE family member D2
chr14_-_71003973 7.43 ENSMUST00000226448.2
ENSMUST00000022696.8
exportin 7
chr6_+_66512401 7.41 ENSMUST00000101343.2
MAD2 mitotic arrest deficient-like 1
chr12_-_11315755 7.41 ENSMUST00000166117.4
ENSMUST00000219600.2
ENSMUST00000218487.2
GEN1, Holliday junction 5' flap endonuclease
chrX_-_8011918 7.19 ENSMUST00000115619.8
ENSMUST00000115617.10
ENSMUST00000040010.10
RNA binding motif (RNP1, RRM) protein 3
chr12_-_30961570 7.01 ENSMUST00000062740.15
ENSMUST00000074038.7
acid phosphatase 1, soluble
chr16_+_94171477 6.86 ENSMUST00000117648.9
ENSMUST00000147352.8
ENSMUST00000150346.8
ENSMUST00000155692.8
ENSMUST00000153988.9
ENSMUST00000139513.9
ENSMUST00000141856.8
ENSMUST00000152117.8
ENSMUST00000150097.8
ENSMUST00000122895.8
ENSMUST00000151770.8
ENSMUST00000231569.2
ENSMUST00000147046.8
ENSMUST00000149885.8
ENSMUST00000127667.8
ENSMUST00000119131.3
ENSMUST00000145883.2
tetratricopeptide repeat domain 3
chrX_-_149595873 6.81 ENSMUST00000131241.2
ENSMUST00000147152.3
ENSMUST00000143843.8
MAGE family member D2
chr6_+_42241916 6.77 ENSMUST00000031895.13
caspase 2
chr13_+_73615316 6.65 ENSMUST00000022099.15
lysophosphatidylcholine acyltransferase 1
chr10_+_80691099 6.64 ENSMUST00000035597.10
signal peptide peptidase like 2B
chr16_-_90524214 6.62 ENSMUST00000099554.5
MIS18 kinetochore protein A
chr3_-_100396635 6.37 ENSMUST00000061455.9
terminal nucleotidyltransferase 5C
chr14_-_71004019 6.30 ENSMUST00000167242.8
exportin 7
chr7_+_44465353 6.23 ENSMUST00000208626.2
ENSMUST00000057195.17
nucleoporin 62
chr12_+_30961650 6.21 ENSMUST00000020997.15
ENSMUST00000110880.3
Sh3 domain YSC-like 1
chr17_-_53996294 6.18 ENSMUST00000024736.14
shugoshin 1
chr19_-_6014210 6.16 ENSMUST00000025752.15
ENSMUST00000165143.3
polymerase (DNA directed), alpha 2
chr2_-_126975804 6.08 ENSMUST00000110387.4
non-SMC condensin I complex, subunit H
chr3_-_89325594 6.00 ENSMUST00000029679.4
CDC28 protein kinase 1b
chr8_-_35962641 5.99 ENSMUST00000033927.8
exoribonuclease 1
chr2_-_154734824 5.97 ENSMUST00000099173.11
eukaryotic translation initiation factor 2, subunit 2 (beta)
chr3_-_54642450 5.93 ENSMUST00000153224.2
exosome component 8
chr3_-_68952030 5.88 ENSMUST00000136512.3
tripartite motif-containing 59
chr2_-_154734702 5.82 ENSMUST00000166171.8
ENSMUST00000161172.3
eukaryotic translation initiation factor 2, subunit 2 (beta)
chr10_+_75047897 5.79 ENSMUST00000218766.2
sperm antigen with calponin homology and coiled-coil domains 1-like
chr15_-_83479312 5.78 ENSMUST00000016901.5
tubulin tyrosine ligase-like family, member 12
chr6_+_86005663 5.75 ENSMUST00000204059.3
adducin 2 (beta)
chr6_+_86005729 5.71 ENSMUST00000203366.3
adducin 2 (beta)
chr2_-_174314741 5.66 ENSMUST00000016401.15
PRELI domain containing 3B
chr2_-_174314672 5.60 ENSMUST00000117442.8
ENSMUST00000141100.2
ENSMUST00000120822.2
PRELI domain containing 3B
chr3_+_79536378 5.58 ENSMUST00000029388.10
RIKEN cDNA 4930579G24 gene
chr16_+_38167352 5.56 ENSMUST00000050273.9
ENSMUST00000120495.2
ENSMUST00000119704.2
cytochrome c oxidase assembly protein 17, copper chaperone
predicted gene 21987
chr1_-_167221344 5.55 ENSMUST00000028005.3
microsomal glutathione S-transferase 3
chr9_+_26941453 5.50 ENSMUST00000073127.14
ENSMUST00000086198.5
non-SMC condensin II complex, subunit D3
chr5_+_33176160 5.49 ENSMUST00000019109.8
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide
chr15_-_99549457 5.46 ENSMUST00000171908.2
ENSMUST00000171702.8
ENSMUST00000109581.3
ENSMUST00000169810.8
ENSMUST00000023756.12
Rac GTPase-activating protein 1
chr19_-_6014159 5.45 ENSMUST00000235224.2
polymerase (DNA directed), alpha 2
chr6_+_66512374 5.41 ENSMUST00000116605.8
MAD2 mitotic arrest deficient-like 1
chr13_-_107158535 5.39 ENSMUST00000117539.8
ENSMUST00000122233.8
ENSMUST00000022204.16
ENSMUST00000159772.8
kinesin family member 2A
chr1_-_128520002 5.37 ENSMUST00000052172.7
ENSMUST00000142893.2
chemokine (C-X-C motif) receptor 4
chr17_-_24698007 5.37 ENSMUST00000234335.2
ENSMUST00000234686.2
ENSMUST00000234941.2
ENSMUST00000234543.2
ENSMUST00000179163.3
ENSMUST00000070888.14
MTOR associated protein, LST8 homolog (S. cerevisiae)
chr15_-_99149810 5.34 ENSMUST00000163506.3
ENSMUST00000229671.2
ENSMUST00000229359.2
ENSMUST00000041190.17
microspherule protein 1
chr4_-_120427449 5.33 ENSMUST00000030381.8
cytidine 5'-triphosphate synthase
chr15_-_36609812 5.32 ENSMUST00000226496.2
poly(A) binding protein, cytoplasmic 1
chr8_+_125624615 5.19 ENSMUST00000034467.7
SprT-like N-terminal domain
chr7_-_133310779 5.17 ENSMUST00000124759.2
ENSMUST00000106144.8
ENSMUST00000106145.10
uroporphyrinogen III synthase
chr5_-_33432310 5.09 ENSMUST00000201372.3
ENSMUST00000202962.4
ENSMUST00000201575.4
ENSMUST00000202868.4
ENSMUST00000079746.10
C-terminal binding protein 1
chr16_+_49675682 5.06 ENSMUST00000114496.3
CD47 antigen (Rh-related antigen, integrin-associated signal transducer)
chr17_-_24470356 5.03 ENSMUST00000115390.5
cyclin F
chr11_-_102815910 5.02 ENSMUST00000021311.10
kinesin family member 18B
chr17_+_56611313 4.96 ENSMUST00000113035.8
ENSMUST00000113039.9
ENSMUST00000142387.2
ubiquitin-like, containing PHD and RING finger domains, 1
chr7_-_133310687 4.96 ENSMUST00000106146.8
uroporphyrinogen III synthase
chr8_+_117648474 4.90 ENSMUST00000034205.5
ENSMUST00000212775.2
centromere protein N
chr10_-_117060377 4.88 ENSMUST00000020382.8
YEATS domain containing 4
chr17_-_24424456 4.88 ENSMUST00000201583.2
ENSMUST00000202925.4
ENSMUST00000167791.9
ENSMUST00000201960.4
ENSMUST00000040474.11
ENSMUST00000201089.4
ENSMUST00000201301.4
ENSMUST00000201805.4
ENSMUST00000168410.9
ENSMUST00000097376.10
TBC1 domain family, member 24
chr19_-_7218363 4.86 ENSMUST00000236769.2
N(alpha)-acetyltransferase 40, NatD catalytic subunit
chr15_-_36609208 4.85 ENSMUST00000001809.15
poly(A) binding protein, cytoplasmic 1
chr4_-_46138397 4.84 ENSMUST00000144495.2
ENSMUST00000107770.2
ENSMUST00000156021.2
ENSMUST00000107772.8
thiosulfate sulfurtransferase (rhodanese)-like domain containing 2
chr3_-_108629594 4.84 ENSMUST00000029482.16
G-protein signalling modulator 2 (AGS3-like, C. elegans)
chr4_-_149221998 4.81 ENSMUST00000176124.8
ENSMUST00000177408.2
ENSMUST00000105695.2
centromere protein S
chr1_-_136273436 4.79 ENSMUST00000192001.6
ENSMUST00000192314.2
calmodulin regulated spectrin-associated protein family, member 2
chr5_-_129085610 4.79 ENSMUST00000031378.14
syntaxin 2
chr9_-_20864096 4.78 ENSMUST00000004202.17
DNA methyltransferase (cytosine-5) 1
chr17_-_57318271 4.76 ENSMUST00000002733.7
general transcription factor IIF, polypeptide 1
chr17_-_66191912 4.65 ENSMUST00000024905.11
ralA binding protein 1
chr17_-_75858835 4.62 ENSMUST00000234785.2
ENSMUST00000112507.4
family with sequence similarity 98, member A
chr7_-_28681209 4.57 ENSMUST00000207683.2
ENSMUST00000066070.7
ENSMUST00000208616.2
eukaryotic translation initiation factor 3, subunit K
chr8_-_84169107 4.56 ENSMUST00000212031.2
ENSMUST00000167525.3
short coiled-coil protein
chr15_-_96358612 4.56 ENSMUST00000047835.8
SR-related CTD-associated factor 11
chr11_-_86964881 4.54 ENSMUST00000020804.8
glycerophosphodiester phosphodiesterase domain containing 1
chr11_+_40624466 4.54 ENSMUST00000020578.11
NudC domain containing 2
chr12_+_78908466 4.52 ENSMUST00000071230.8
eukaryotic translation initiation factor 2, subunit 1 alpha
chr14_-_57015748 4.51 ENSMUST00000022507.13
ENSMUST00000163924.2
paraspeckle protein 1
chr19_-_7218512 4.51 ENSMUST00000025675.11
N(alpha)-acetyltransferase 40, NatD catalytic subunit
chr18_-_73948501 4.51 ENSMUST00000025439.5
malic enzyme 2, NAD(+)-dependent, mitochondrial
chr11_+_40624763 4.50 ENSMUST00000127382.2
NudC domain containing 2
chr18_+_34542468 4.46 ENSMUST00000014647.9
ENSMUST00000166156.9
polycystic kidney disease 2-like 2
chr5_+_88912855 4.45 ENSMUST00000031311.10
deoxycytidine kinase
chrX_+_133208833 4.44 ENSMUST00000081064.12
ENSMUST00000101251.8
ENSMUST00000129782.2
centromere protein I
chr5_+_97145533 4.44 ENSMUST00000112974.6
ENSMUST00000035635.10
BMP2 inducible kinase
chr11_-_69838971 4.43 ENSMUST00000179298.3
ENSMUST00000018710.13
ENSMUST00000135437.3
ENSMUST00000141837.9
ENSMUST00000142500.8
solute carrier family 2 (facilitated glucose transporter), member 4
chr9_-_44255456 4.43 ENSMUST00000077353.15
hydroxymethylbilane synthase
chr10_+_20223516 4.40 ENSMUST00000169712.3
ENSMUST00000217608.2
mitochondrial fission regulator 2
chr7_-_45045097 4.38 ENSMUST00000211121.2
ENSMUST00000074575.11
small nuclear ribonucleoprotein 70 (U1)
chr10_+_13376745 4.36 ENSMUST00000060212.13
ENSMUST00000121465.3
fucosidase, alpha-L- 2, plasma
chr14_-_58063585 4.34 ENSMUST00000022536.3
spindle and kinetochore associated complex subunit 3
chr11_+_87017878 4.33 ENSMUST00000041282.13
tripartite motif-containing 37
chr9_+_120400510 4.32 ENSMUST00000165532.3
ribosomal protein L14
chr15_+_84807582 4.32 ENSMUST00000165443.4
nucleoporin 50
chr11_-_86435579 4.32 ENSMUST00000138810.3
ENSMUST00000058286.9
ENSMUST00000154617.8
ribosomal protein S6 kinase, polypeptide 1
chr9_+_70586232 4.31 ENSMUST00000067880.13
a disintegrin and metallopeptidase domain 10
chr7_+_24246575 4.30 ENSMUST00000063249.9
X-ray repair complementing defective repair in Chinese hamster cells 1
chr8_+_86026318 4.26 ENSMUST00000170141.3
ENSMUST00000034132.13
origin recognition complex, subunit 6
chr7_+_125043806 4.26 ENSMUST00000033010.9
ENSMUST00000135129.2
lysine (K)-specific demethylase 8
chr12_+_17594795 4.26 ENSMUST00000171737.3
ornithine decarboxylase, structural 1
chr5_-_77457895 4.24 ENSMUST00000047860.9
nitric oxide associated 1
chr16_-_90841360 4.22 ENSMUST00000118522.8
PAX3 and PAX7 binding protein 1
chr10_-_81214293 4.20 ENSMUST00000140901.8
fizzy and cell division cycle 20 related 1
chr11_+_117006020 4.19 ENSMUST00000103026.10
ENSMUST00000090433.6
SEC14-like lipid binding 1
chr17_+_56891973 4.18 ENSMUST00000182533.8
ENSMUST00000182800.8
ENSMUST00000095224.11
scaffold attachment factor B
chr4_+_115696388 4.15 ENSMUST00000019677.12
ENSMUST00000144427.8
ENSMUST00000106513.10
ENSMUST00000130819.8
ENSMUST00000151203.8
ENSMUST00000140315.2
MAP kinase-interacting serine/threonine kinase 1
chr2_+_155798457 4.14 ENSMUST00000109619.9
ENSMUST00000094421.11
ENSMUST00000039994.14
ENSMUST00000151569.8
ENSMUST00000109618.2
centrosomal protein 250
chr17_-_45744637 4.14 ENSMUST00000024727.10
cell division cycle 5-like (S. pombe)
chr7_+_44465714 4.14 ENSMUST00000208172.2
nucleoporin 62
chr1_+_159059869 4.11 ENSMUST00000076894.11
COP1, E3 ubiquitin ligase
chr8_-_22675773 4.09 ENSMUST00000046916.9
cytoskeleton associated protein 2
chr1_-_191307648 4.08 ENSMUST00000027933.11
denticleless E3 ubiquitin protein ligase
chr15_+_84807640 4.08 ENSMUST00000230411.2
nucleoporin 50
chr5_+_77457994 4.07 ENSMUST00000031167.6
polymerase (RNA) II (DNA directed) polypeptide B
chr6_-_125471666 4.05 ENSMUST00000032492.9
CD9 antigen
chr16_+_49676130 4.03 ENSMUST00000230641.2
CD47 antigen (Rh-related antigen, integrin-associated signal transducer)
chr13_+_104315301 4.01 ENSMUST00000022225.12
ENSMUST00000069187.12
tripartite motif-containing 23
chr5_+_123214332 4.01 ENSMUST00000067505.15
ENSMUST00000111619.10
ENSMUST00000160344.2
transmembrane protein 120B
chr10_+_80100812 4.00 ENSMUST00000105362.8
ENSMUST00000105361.10
DAZ associated protein 1
chr10_+_20188207 4.00 ENSMUST00000092678.10
ENSMUST00000043881.12
BCL2-associated transcription factor 1
chr8_-_71060911 4.00 ENSMUST00000210580.2
ENSMUST00000211608.2
ENSMUST00000049908.11
single stranded DNA binding protein 4
chr11_+_59099147 3.99 ENSMUST00000020719.7
RIKEN cDNA 2310033P09 gene
chr17_-_80514725 3.98 ENSMUST00000234696.2
ENSMUST00000235069.2
ENSMUST00000063417.11
serine and arginine-rich splicing factor 7
chr11_+_117005958 3.98 ENSMUST00000021177.15
SEC14-like lipid binding 1
chr7_+_44465806 3.97 ENSMUST00000207103.2
ENSMUST00000118125.9
nucleoporin 62
interleukin 4 induced 1
chr7_-_24919247 3.97 ENSMUST00000058702.7
death effector domain-containing DNA binding protein 2
chr8_+_13388745 3.97 ENSMUST00000209885.2
ENSMUST00000209396.2
transcription factor Dp 1
chr5_+_143534455 3.96 ENSMUST00000169329.8
ENSMUST00000067145.12
ENSMUST00000119488.2
ENSMUST00000118121.2
ENSMUST00000200267.2
ENSMUST00000196487.2
family with sequence similarity 220, member A
family with sequence similarity 220, member A
chr19_-_45771939 3.94 ENSMUST00000026243.5
O-GlcNAcase
chr10_-_23663086 3.89 ENSMUST00000073926.8
ribosomal protein S12
chr14_-_47514248 3.84 ENSMUST00000187531.8
ENSMUST00000111790.2
WD repeat and HMG-box DNA binding protein 1
chr10_-_23663109 3.84 ENSMUST00000218221.2
ENSMUST00000218107.2
ribosomal protein S12
chr2_-_34644376 3.83 ENSMUST00000142436.2
ENSMUST00000028224.15
ENSMUST00000113099.10
GTPase activating protein and VPS9 domains 1
chr10_+_62782786 3.83 ENSMUST00000131422.8
DNA replication helicase/nuclease 2
chr14_+_31887739 3.82 ENSMUST00000111994.10
ENSMUST00000168114.8
ENSMUST00000168034.8
nuclear receptor coactivator 4
chr13_-_100922910 3.81 ENSMUST00000174038.2
ENSMUST00000091295.14
ENSMUST00000072119.15
cyclin B1
chr17_-_71833752 3.79 ENSMUST00000232863.2
ENSMUST00000024851.10
NDC80 kinetochore complex component
chr4_-_45408646 3.79 ENSMUST00000153904.2
ENSMUST00000132815.3
ENSMUST00000107796.8
ENSMUST00000116341.4
solute carrier family 25, member 51
chr13_-_98951890 3.79 ENSMUST00000040340.16
ENSMUST00000179563.8
ENSMUST00000109403.2
FCH domain only 2
chr2_+_30306116 3.76 ENSMUST00000113601.10
ENSMUST00000113603.10
protein phosphatase 2 protein activator
chr15_+_79975520 3.75 ENSMUST00000009728.13
ENSMUST00000009727.12
synaptogyrin 1
chr17_+_27136065 3.73 ENSMUST00000078961.6
kinesin family member C5B
chr7_-_55669702 3.71 ENSMUST00000052204.6
non imprinted in Prader-Willi/Angelman syndrome 1 homolog (human)
chr11_+_32155415 3.70 ENSMUST00000039601.10
ENSMUST00000149043.3
small nuclear ribonucleoprotein 25 (U11/U12)
chr14_-_47514308 3.69 ENSMUST00000111792.9
WD repeat and HMG-box DNA binding protein 1
chr16_-_16939548 3.66 ENSMUST00000231297.2
ENSMUST00000231558.2
RIKEN cDNA 2610318N02 gene
chr2_-_150881283 3.66 ENSMUST00000128627.2
ENSMUST00000066640.5
ninein-like
N-acetylneuraminic acid phosphatase
chr8_+_71858647 3.65 ENSMUST00000119976.8
ENSMUST00000120725.2
ankyrin repeat and LEM domain containing 1
chr7_-_35346553 3.65 ENSMUST00000120714.2
programmed cell death 5
chr15_-_99149794 3.65 ENSMUST00000229926.2
microspherule protein 1
chr19_+_6414587 3.62 ENSMUST00000155973.2
splicing factor 1
chr11_+_116089678 3.60 ENSMUST00000021130.7
TEN1 telomerase capping complex subunit
chr9_-_107956474 3.60 ENSMUST00000162355.8
ENSMUST00000047746.13
ENSMUST00000174504.8
ENSMUST00000178267.8
ENSMUST00000160649.8
ring finger protein 123
chr3_-_108352499 3.60 ENSMUST00000090553.12
ENSMUST00000153499.2
seryl-aminoacyl-tRNA synthetase
chr7_+_4140031 3.60 ENSMUST00000128756.8
ENSMUST00000132086.8
ENSMUST00000037472.13
ENSMUST00000117274.8
ENSMUST00000121270.8
ENSMUST00000144248.3
leukocyte receptor cluster (LRC) member 8
chr10_-_80691009 3.58 ENSMUST00000220225.2
ENSMUST00000035775.9
LSM7 homolog, U6 small nuclear RNA and mRNA degradation associated
chr10_+_59159118 3.58 ENSMUST00000009789.15
ENSMUST00000092512.11
ENSMUST00000105466.3
procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), alpha 1 polypeptide
chr5_+_74696110 3.57 ENSMUST00000080164.12
ENSMUST00000113536.8
ENSMUST00000113534.9
ENSMUST00000113535.9
ENSMUST00000120618.6
FIP1 like 1 (S. cerevisiae)
chr1_-_131066004 3.56 ENSMUST00000016670.9
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
chr2_+_30306045 3.56 ENSMUST00000042055.10
protein phosphatase 2 protein activator
chr3_+_68912302 3.56 ENSMUST00000136502.8
ENSMUST00000107803.7
structural maintenance of chromosomes 4
chr5_+_32616187 3.56 ENSMUST00000015100.15
protein phosphatase 1 catalytic subunit beta
chr19_-_5962862 3.55 ENSMUST00000136983.8
D4, zinc and double PHD fingers family 2
chr13_-_76166789 3.54 ENSMUST00000179078.9
ENSMUST00000167271.9
Rieske (Fe-S) domain containing
chr11_+_53458188 3.54 ENSMUST00000057330.15
ENSMUST00000120613.9
ENSMUST00000173744.8
ENSMUST00000118353.9
kinesin family member 3A
chr10_-_76073656 3.53 ENSMUST00000099572.10
ENSMUST00000020452.12
ENSMUST00000099571.10
protein arginine N-methyltransferase 2
chr16_-_3821614 3.52 ENSMUST00000171658.2
ENSMUST00000171762.2
SLX4 structure-specific endonuclease subunit homolog (S. cerevisiae)
chr4_-_131776368 3.52 ENSMUST00000105981.9
ENSMUST00000084253.10
ENSMUST00000141291.3
erythrocyte membrane protein band 4.1
chr3_+_122717852 3.51 ENSMUST00000106429.6
RIKEN cDNA 1810037I17 gene
chr10_-_62628008 3.49 ENSMUST00000217768.2
ENSMUST00000020268.7
ENSMUST00000218946.2
ENSMUST00000219527.2
cell division cycle and apoptosis regulator 1
chr3_+_103078971 3.48 ENSMUST00000005830.15
breast carcinoma amplified sequence 2
chr19_-_24533183 3.47 ENSMUST00000112673.9
ENSMUST00000025800.15
phosphatidylinositol-4-phosphate 5-kinase, type 1 beta
chr4_+_6365694 3.47 ENSMUST00000175769.8
ENSMUST00000140830.8
ENSMUST00000108374.8
syndecan binding protein

Network of associatons between targets according to the STRING database.

First level regulatory network of Nrf1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
4.1 24.7 GO:0070458 detoxification of nitrogen compound(GO:0051410) cellular detoxification of nitrogen compound(GO:0070458)
4.1 28.6 GO:0045585 regulation of cytotoxic T cell differentiation(GO:0045583) positive regulation of cytotoxic T cell differentiation(GO:0045585)
3.8 11.3 GO:0006407 rRNA export from nucleus(GO:0006407)
3.7 11.0 GO:0051439 negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle(GO:0051436) regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle(GO:0051439)
3.6 10.8 GO:0071163 DNA replication preinitiation complex assembly(GO:0071163)
3.4 10.1 GO:0006780 uroporphyrinogen III biosynthetic process(GO:0006780)
3.2 9.6 GO:1904172 positive regulation of bleb assembly(GO:1904172)
2.9 8.7 GO:1900195 positive regulation of oocyte maturation(GO:1900195)
2.8 25.4 GO:0090267 positive regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090267)
2.8 8.4 GO:2000769 regulation of establishment or maintenance of cell polarity regulating cell shape(GO:2000769) positive regulation of establishment or maintenance of cell polarity regulating cell shape(GO:2000771)
2.5 20.1 GO:0046601 positive regulation of centriole replication(GO:0046601)
2.5 9.8 GO:0000727 double-strand break repair via break-induced replication(GO:0000727)
2.4 7.3 GO:0030472 mitotic spindle organization in nucleus(GO:0030472)
2.4 9.5 GO:0051316 attachment of spindle microtubules to kinetochore involved in meiotic chromosome segregation(GO:0051316)
2.1 20.9 GO:0010032 meiotic chromosome condensation(GO:0010032)
2.0 5.9 GO:0006434 seryl-tRNA aminoacylation(GO:0006434)
2.0 5.9 GO:0034476 U1 snRNA 3'-end processing(GO:0034473) U5 snRNA 3'-end processing(GO:0034476)
2.0 5.9 GO:1903632 positive regulation of aminoacyl-tRNA ligase activity(GO:1903632)
1.9 5.6 GO:1904959 regulation of cytochrome-c oxidase activity(GO:1904959)
1.8 5.5 GO:2000299 negative regulation of Rho-dependent protein serine/threonine kinase activity(GO:2000299)
1.8 7.3 GO:0090309 positive regulation of methylation-dependent chromatin silencing(GO:0090309)
1.8 5.5 GO:0006713 glucocorticoid catabolic process(GO:0006713)
1.8 9.0 GO:1904751 positive regulation of protein localization to nucleolus(GO:1904751)
1.8 14.3 GO:0070294 renal sodium ion absorption(GO:0070294)
1.8 3.5 GO:0072429 response to intra-S DNA damage checkpoint signaling(GO:0072429)
1.7 5.1 GO:0042128 nitrate assimilation(GO:0042128)
1.7 6.7 GO:0000915 assembly of actomyosin apparatus involved in cytokinesis(GO:0000912) actomyosin contractile ring assembly(GO:0000915) actomyosin contractile ring organization(GO:0044837)
1.7 10.1 GO:0003065 positive regulation of heart rate by epinephrine(GO:0003065)
1.7 8.3 GO:0071921 establishment of sister chromatid cohesion(GO:0034085) cohesin loading(GO:0071921) regulation of cohesin loading(GO:0071922)
1.7 6.7 GO:2001245 regulation of phosphatidylcholine biosynthetic process(GO:2001245)
1.6 4.9 GO:0097051 establishment of protein localization to endoplasmic reticulum membrane(GO:0097051)
1.5 7.7 GO:0035617 stress granule disassembly(GO:0035617)
1.5 6.1 GO:0006409 tRNA export from nucleus(GO:0006409) tRNA-containing ribonucleoprotein complex export from nucleus(GO:0071431)
1.5 7.5 GO:0070829 heterochromatin maintenance(GO:0070829)
1.5 4.4 GO:0018160 peptidyl-pyrromethane cofactor linkage(GO:0018160)
1.5 5.9 GO:0010424 DNA methylation on cytosine within a CG sequence(GO:0010424)
1.5 4.4 GO:0098928 presynaptic signal transduction(GO:0098928) presynapse to nucleus signaling pathway(GO:0099526)
1.4 1.4 GO:0016078 tRNA catabolic process(GO:0016078)
1.4 6.8 GO:1903553 positive regulation of extracellular exosome assembly(GO:1903553)
1.3 14.8 GO:0040016 embryonic cleavage(GO:0040016)
1.3 9.4 GO:2000623 regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
1.3 9.2 GO:0018002 N-terminal peptidyl-serine acetylation(GO:0017198) N-terminal peptidyl-glutamic acid acetylation(GO:0018002) peptidyl-serine acetylation(GO:0030920)
1.3 6.5 GO:0090669 telomerase RNA stabilization(GO:0090669)
1.3 10.4 GO:0006290 pyrimidine dimer repair(GO:0006290)
1.3 15.4 GO:0045876 positive regulation of sister chromatid cohesion(GO:0045876)
1.3 6.4 GO:0033387 putrescine biosynthetic process from ornithine(GO:0033387)
1.2 4.8 GO:1903575 cornified envelope assembly(GO:1903575)
1.2 8.4 GO:0036353 histone H2A-K119 monoubiquitination(GO:0036353)
1.2 7.1 GO:0042117 monocyte activation(GO:0042117)
1.2 8.2 GO:0015871 choline transport(GO:0015871)
1.2 6.9 GO:0051661 maintenance of centrosome location(GO:0051661)
1.2 3.5 GO:1900368 regulation of RNA interference(GO:1900368)
1.1 6.9 GO:2000676 positive regulation of type B pancreatic cell apoptotic process(GO:2000676)
1.1 4.6 GO:0060382 regulation of DNA strand elongation(GO:0060382)
1.1 3.4 GO:0032241 positive regulation of nucleobase-containing compound transport(GO:0032241)
1.1 4.5 GO:0016584 nucleosome positioning(GO:0016584)
1.1 1.1 GO:2000642 negative regulation of early endosome to late endosome transport(GO:2000642)
1.1 6.6 GO:0061641 CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641)
1.1 3.2 GO:0035722 interleukin-12-mediated signaling pathway(GO:0035722) cellular response to interleukin-12(GO:0071349)
1.1 5.4 GO:0035470 positive regulation of vascular wound healing(GO:0035470)
1.1 4.2 GO:0071544 diphosphoinositol polyphosphate catabolic process(GO:0071544)
1.0 11.2 GO:0008228 opsonization(GO:0008228)
1.0 3.0 GO:0006285 base-excision repair, AP site formation(GO:0006285)
1.0 6.9 GO:0045040 protein import into mitochondrial outer membrane(GO:0045040)
1.0 7.9 GO:0060623 regulation of chromosome condensation(GO:0060623)
1.0 2.9 GO:1905000 regulation of membrane repolarization during atrial cardiac muscle cell action potential(GO:1905000)
1.0 4.8 GO:0007084 mitotic nuclear envelope reassembly(GO:0007084)
1.0 16.3 GO:0036297 interstrand cross-link repair(GO:0036297)
1.0 3.8 GO:1902990 mitotic telomere maintenance via semi-conservative replication(GO:1902990)
0.9 8.5 GO:1903608 protein localization to cytoplasmic stress granule(GO:1903608)
0.9 4.7 GO:1904170 regulation of bleb assembly(GO:1904170)
0.9 4.6 GO:1903378 positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903378)
0.9 0.9 GO:0090168 Golgi reassembly(GO:0090168)
0.9 5.5 GO:0019276 UDP-N-acetylgalactosamine metabolic process(GO:0019276)
0.9 1.8 GO:0000480 endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000480)
0.9 8.1 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
0.9 1.8 GO:0018312 peptidyl-serine ADP-ribosylation(GO:0018312)
0.9 8.0 GO:2000234 positive regulation of ribosome biogenesis(GO:0090070) positive regulation of rRNA processing(GO:2000234)
0.9 4.5 GO:0046125 pyrimidine deoxyribonucleoside metabolic process(GO:0046125)
0.9 6.2 GO:0031125 rRNA 3'-end processing(GO:0031125)
0.9 2.7 GO:0000451 rRNA 2'-O-methylation(GO:0000451)
0.9 2.6 GO:0070104 negative regulation of interleukin-6-mediated signaling pathway(GO:0070104) regulation of macrophage colony-stimulating factor signaling pathway(GO:1902226) regulation of response to macrophage colony-stimulating factor(GO:1903969) regulation of cellular response to macrophage colony-stimulating factor stimulus(GO:1903972)
0.9 11.4 GO:0019985 translesion synthesis(GO:0019985)
0.9 2.6 GO:0002543 activation of blood coagulation via clotting cascade(GO:0002543) phosphatidylserine exposure on blood platelet(GO:0097045)
0.9 1.7 GO:0010847 regulation of chromatin assembly(GO:0010847)
0.9 1.7 GO:0072695 negative regulation of DNA recombination at telomere(GO:0048239) regulation of DNA recombination at telomere(GO:0072695)
0.8 17.8 GO:0006474 N-terminal protein amino acid acetylation(GO:0006474)
0.8 1.7 GO:0000478 endonucleolytic cleavage involved in rRNA processing(GO:0000478) endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000479)
0.8 2.5 GO:0045041 protein import into mitochondrial intermembrane space(GO:0045041)
0.8 3.3 GO:1902396 protein localization to bicellular tight junction(GO:1902396)
0.8 2.5 GO:1904976 response to bleomycin(GO:1904975) cellular response to bleomycin(GO:1904976)
0.8 1.7 GO:0051031 tRNA transport(GO:0051031)
0.8 1.7 GO:1904872 regulation of telomerase RNA localization to Cajal body(GO:1904872)
0.8 2.5 GO:0071874 cellular response to norepinephrine stimulus(GO:0071874)
0.8 0.8 GO:2000767 positive regulation of cytoplasmic translation(GO:2000767)
0.8 2.4 GO:0030208 dermatan sulfate biosynthetic process(GO:0030208)
0.8 3.9 GO:0035616 histone H2B conserved C-terminal lysine deubiquitination(GO:0035616)
0.8 1.5 GO:1904430 negative regulation of t-circle formation(GO:1904430)
0.8 2.3 GO:0061763 multivesicular body-lysosome fusion(GO:0061763)
0.8 3.8 GO:0045950 negative regulation of mitotic recombination(GO:0045950)
0.8 2.3 GO:2000232 regulation of rRNA processing(GO:2000232)
0.8 2.3 GO:1902630 regulation of membrane hyperpolarization(GO:1902630)
0.7 27.7 GO:0006270 DNA replication initiation(GO:0006270)
0.7 5.0 GO:0000320 re-entry into mitotic cell cycle(GO:0000320)
0.7 4.7 GO:0030263 apoptotic chromosome condensation(GO:0030263)
0.7 2.0 GO:1904924 negative regulation of mitophagy in response to mitochondrial depolarization(GO:1904924)
0.7 2.0 GO:0061536 glycine secretion(GO:0061536) glycine secretion, neurotransmission(GO:0061537)
0.7 18.9 GO:0010569 regulation of double-strand break repair via homologous recombination(GO:0010569)
0.7 4.7 GO:0019661 glucose catabolic process to lactate(GO:0019659) glycolytic fermentation(GO:0019660) glucose catabolic process to lactate via pyruvate(GO:0019661)
0.7 2.7 GO:0043418 homocysteine catabolic process(GO:0043418)
0.7 2.6 GO:0000973 posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000973)
0.7 4.0 GO:0036451 cap mRNA methylation(GO:0036451)
0.7 5.2 GO:0046349 amino sugar biosynthetic process(GO:0046349)
0.6 3.2 GO:0070966 nuclear-transcribed mRNA catabolic process, no-go decay(GO:0070966)
0.6 7.7 GO:0009452 7-methylguanosine RNA capping(GO:0009452) RNA capping(GO:0036260)
0.6 2.5 GO:0046084 adenine salvage(GO:0006168) adenine metabolic process(GO:0046083) adenine biosynthetic process(GO:0046084)
0.6 0.6 GO:0061511 centriole elongation(GO:0061511)
0.6 1.9 GO:0035425 autocrine signaling(GO:0035425)
0.6 2.5 GO:0001732 formation of cytoplasmic translation initiation complex(GO:0001732)
0.6 5.0 GO:0050684 regulation of mRNA processing(GO:0050684)
0.6 2.5 GO:1905077 negative regulation of interleukin-17 secretion(GO:1905077)
0.6 4.3 GO:0048633 positive regulation of skeletal muscle tissue growth(GO:0048633)
0.6 1.8 GO:0072356 chromosome passenger complex localization to kinetochore(GO:0072356)
0.6 5.5 GO:0000012 single strand break repair(GO:0000012)
0.6 1.2 GO:0033122 negative regulation of purine nucleotide catabolic process(GO:0033122)
0.6 6.7 GO:0035234 ectopic germ cell programmed cell death(GO:0035234)
0.6 1.8 GO:0032066 nucleolus to nucleoplasm transport(GO:0032066)
0.6 1.8 GO:0009224 CMP salvage(GO:0006238) CMP biosynthetic process(GO:0009224) pyrimidine ribonucleotide salvage(GO:0010138) pyrimidine nucleotide salvage(GO:0032262) UMP salvage(GO:0044206) CMP metabolic process(GO:0046035)
0.6 3.4 GO:0030423 targeting of mRNA for destruction involved in RNA interference(GO:0030423)
0.6 2.3 GO:0006529 asparagine biosynthetic process(GO:0006529)
0.6 2.2 GO:0072717 cellular response to actinomycin D(GO:0072717)
0.6 13.4 GO:0046597 negative regulation of viral entry into host cell(GO:0046597)
0.6 5.5 GO:0051315 attachment of mitotic spindle microtubules to kinetochore(GO:0051315)
0.6 2.8 GO:0046501 protoporphyrinogen IX metabolic process(GO:0046501)
0.6 1.7 GO:0007181 transforming growth factor beta receptor complex assembly(GO:0007181)
0.5 2.1 GO:0006203 dGTP catabolic process(GO:0006203) dATP catabolic process(GO:0046061)
0.5 2.7 GO:0007023 post-chaperonin tubulin folding pathway(GO:0007023)
0.5 1.6 GO:0042275 error-free postreplication DNA repair(GO:0042275)
0.5 1.6 GO:0042822 pyridoxal phosphate metabolic process(GO:0042822)
0.5 4.7 GO:0006004 fucose metabolic process(GO:0006004)
0.5 1.6 GO:0019389 glucuronoside metabolic process(GO:0019389)
0.5 5.2 GO:0031293 membrane protein intracellular domain proteolysis(GO:0031293)
0.5 2.1 GO:0048298 positive regulation of isotype switching to IgA isotypes(GO:0048298)
0.5 1.5 GO:0000469 cleavage involved in rRNA processing(GO:0000469)
0.5 1.5 GO:0070376 regulation of ERK5 cascade(GO:0070376)
0.5 2.1 GO:1902896 terminal web assembly(GO:1902896)
0.5 5.6 GO:0032056 positive regulation of translation in response to stress(GO:0032056)
0.5 8.1 GO:0016926 protein desumoylation(GO:0016926)
0.5 4.5 GO:0071684 blastocyst hatching(GO:0001835) hatching(GO:0035188) organism emergence from protective structure(GO:0071684)
0.5 10.0 GO:0034508 centromere complex assembly(GO:0034508)
0.5 3.0 GO:0035694 mitochondrial protein catabolic process(GO:0035694)
0.5 9.4 GO:0036093 germ cell proliferation(GO:0036093)
0.5 5.9 GO:0090308 regulation of methylation-dependent chromatin silencing(GO:0090308)
0.5 0.5 GO:2000049 positive regulation of cell-cell adhesion mediated by cadherin(GO:2000049)
0.5 3.4 GO:1901300 positive regulation of hydrogen peroxide-mediated programmed cell death(GO:1901300)
0.5 2.4 GO:0071894 histone H2B conserved C-terminal lysine ubiquitination(GO:0071894)
0.5 1.0 GO:0002314 germinal center B cell differentiation(GO:0002314)
0.5 1.4 GO:0000350 generation of catalytic spliceosome for second transesterification step(GO:0000350)
0.5 1.4 GO:0051892 negative regulation of cardioblast differentiation(GO:0051892)
0.5 1.0 GO:2000814 positive regulation of barbed-end actin filament capping(GO:2000814)
0.5 10.5 GO:0034063 stress granule assembly(GO:0034063)
0.5 1.9 GO:0035822 meiotic gene conversion(GO:0006311) gene conversion(GO:0035822)
0.5 3.3 GO:0000056 ribosomal small subunit export from nucleus(GO:0000056)
0.5 2.8 GO:0050916 sensory perception of sweet taste(GO:0050916)
0.5 1.4 GO:0035544 negative regulation of SNARE complex assembly(GO:0035544)
0.5 4.2 GO:0006108 malate metabolic process(GO:0006108)
0.5 3.3 GO:0006348 chromatin silencing at telomere(GO:0006348)
0.5 1.9 GO:0032805 positive regulation of low-density lipoprotein particle receptor catabolic process(GO:0032805)
0.5 2.3 GO:0070213 protein auto-ADP-ribosylation(GO:0070213)
0.5 1.4 GO:0019085 early viral transcription(GO:0019085)
0.5 6.9 GO:1903405 protein localization to nuclear body(GO:1903405) protein localization to Cajal body(GO:1904867) regulation of protein localization to Cajal body(GO:1904869) positive regulation of protein localization to Cajal body(GO:1904871)
0.5 1.4 GO:0006428 isoleucyl-tRNA aminoacylation(GO:0006428)
0.5 2.7 GO:0099527 postsynapse to nucleus signaling pathway(GO:0099527)
0.5 3.6 GO:0051081 membrane disassembly(GO:0030397) nuclear envelope disassembly(GO:0051081)
0.5 15.9 GO:0051016 barbed-end actin filament capping(GO:0051016)
0.4 4.5 GO:0098789 pre-mRNA cleavage required for polyadenylation(GO:0098789)
0.4 8.4 GO:0006622 protein targeting to lysosome(GO:0006622)
0.4 5.8 GO:0061635 regulation of protein complex stability(GO:0061635)
0.4 2.7 GO:0035553 oxidative single-stranded RNA demethylation(GO:0035553)
0.4 4.4 GO:0002349 histamine production involved in inflammatory response(GO:0002349) histamine secretion involved in inflammatory response(GO:0002441) histamine secretion by mast cell(GO:0002553)
0.4 1.8 GO:2001137 positive regulation of endocytic recycling(GO:2001137)
0.4 4.4 GO:0034501 protein localization to kinetochore(GO:0034501)
0.4 0.9 GO:0070358 actin polymerization-dependent cell motility(GO:0070358)
0.4 1.3 GO:1990180 mitochondrial tRNA 3'-end processing(GO:1990180)
0.4 6.5 GO:0000470 maturation of LSU-rRNA(GO:0000470)
0.4 2.1 GO:0033314 mitotic DNA replication checkpoint(GO:0033314)
0.4 2.5 GO:0033140 negative regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033140)
0.4 2.1 GO:2000325 regulation of ligand-dependent nuclear receptor transcription coactivator activity(GO:2000325) positive regulation of ligand-dependent nuclear receptor transcription coactivator activity(GO:2000327)
0.4 2.1 GO:0000447 endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000447)
0.4 2.9 GO:0000972 transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000972)
0.4 2.8 GO:0060339 negative regulation of type I interferon-mediated signaling pathway(GO:0060339)
0.4 0.4 GO:0072752 cellular response to rapamycin(GO:0072752)
0.4 1.6 GO:0071557 histone H3-K27 demethylation(GO:0071557)
0.4 4.0 GO:0070345 negative regulation of fat cell proliferation(GO:0070345)
0.4 7.9 GO:0008608 attachment of spindle microtubules to kinetochore(GO:0008608)
0.4 2.0 GO:0006344 maintenance of chromatin silencing(GO:0006344)
0.4 3.5 GO:0045898 regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045898)
0.4 8.5 GO:0000460 maturation of 5.8S rRNA(GO:0000460)
0.4 4.2 GO:0000244 spliceosomal tri-snRNP complex assembly(GO:0000244)
0.4 1.9 GO:0030997 regulation of centriole-centriole cohesion(GO:0030997)
0.4 1.2 GO:1990022 RNA polymerase II complex import to nucleus(GO:0044376) RNA polymerase III complex localization to nucleus(GO:1990022)
0.4 3.8 GO:0051123 RNA polymerase II transcriptional preinitiation complex assembly(GO:0051123)
0.4 1.5 GO:0016185 synaptic vesicle budding from presynaptic endocytic zone membrane(GO:0016185)
0.4 1.5 GO:0001306 age-dependent response to oxidative stress(GO:0001306) age-dependent general metabolic decline(GO:0007571) amino acid neurotransmitter reuptake(GO:0051933) glutamate reuptake(GO:0051935)
0.4 3.8 GO:0046784 viral mRNA export from host cell nucleus(GO:0046784)
0.4 8.3 GO:0016973 poly(A)+ mRNA export from nucleus(GO:0016973)
0.4 4.1 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.4 2.2 GO:0034720 histone H3-K4 demethylation(GO:0034720)
0.4 1.1 GO:0070375 ERK5 cascade(GO:0070375)
0.4 2.6 GO:1903527 positive regulation of membrane tubulation(GO:1903527)
0.4 1.5 GO:0070537 histone H2A K63-linked deubiquitination(GO:0070537)
0.4 1.1 GO:0010825 positive regulation of centrosome duplication(GO:0010825)
0.4 9.4 GO:0043968 histone H2A acetylation(GO:0043968)
0.4 2.9 GO:1900264 regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264)
0.4 1.8 GO:0015960 diadenosine polyphosphate biosynthetic process(GO:0015960) diadenosine tetraphosphate metabolic process(GO:0015965) diadenosine tetraphosphate biosynthetic process(GO:0015966)
0.4 1.4 GO:0018026 peptidyl-lysine monomethylation(GO:0018026)
0.4 2.1 GO:1903347 negative regulation of bicellular tight junction assembly(GO:1903347)
0.4 5.3 GO:0046036 CTP biosynthetic process(GO:0006241) CTP metabolic process(GO:0046036)
0.4 1.8 GO:0033313 meiotic cell cycle checkpoint(GO:0033313)
0.4 0.7 GO:0072385 minus-end-directed organelle transport along microtubule(GO:0072385)
0.3 4.9 GO:0030261 chromosome condensation(GO:0030261)
0.3 1.0 GO:0035519 protein K29-linked ubiquitination(GO:0035519)
0.3 1.0 GO:1990859 cellular response to endothelin(GO:1990859)
0.3 1.4 GO:0071169 establishment of protein localization to chromatin(GO:0071169)
0.3 1.4 GO:0032849 positive regulation of cellular pH reduction(GO:0032849)
0.3 3.1 GO:0031145 anaphase-promoting complex-dependent catabolic process(GO:0031145)
0.3 4.5 GO:0005981 regulation of glycogen catabolic process(GO:0005981)
0.3 2.1 GO:0036507 protein deglycosylation involved in glycoprotein catabolic process(GO:0035977) protein demannosylation(GO:0036507) protein alpha-1,2-demannosylation(GO:0036508) glycoprotein ERAD pathway(GO:0097466) mannose trimming involved in glycoprotein ERAD pathway(GO:1904382)
0.3 6.2 GO:0070544 histone H3-K36 demethylation(GO:0070544)
0.3 1.0 GO:1903336 negative regulation of vacuolar transport(GO:1903336)
0.3 3.0 GO:0034244 negative regulation of transcription elongation from RNA polymerase II promoter(GO:0034244)
0.3 1.0 GO:0075525 viral translational termination-reinitiation(GO:0075525)
0.3 1.0 GO:0016240 autophagosome docking(GO:0016240)
0.3 1.3 GO:0014873 response to muscle activity involved in regulation of muscle adaptation(GO:0014873)
0.3 1.0 GO:1903061 positive regulation of protein lipidation(GO:1903061)
0.3 11.0 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.3 6.7 GO:0033327 Leydig cell differentiation(GO:0033327)
0.3 3.3 GO:1900364 negative regulation of mRNA polyadenylation(GO:1900364)
0.3 1.3 GO:0070100 negative regulation of chemokine-mediated signaling pathway(GO:0070100)
0.3 5.3 GO:0016180 snRNA processing(GO:0016180)
0.3 13.1 GO:0035196 dsRNA fragmentation(GO:0031050) production of miRNAs involved in gene silencing by miRNA(GO:0035196) production of small RNA involved in gene silencing by RNA(GO:0070918)
0.3 1.6 GO:0006432 phenylalanyl-tRNA aminoacylation(GO:0006432)
0.3 0.7 GO:1902174 positive regulation of keratinocyte apoptotic process(GO:1902174)
0.3 14.4 GO:0007026 negative regulation of microtubule depolymerization(GO:0007026)
0.3 2.0 GO:0060178 regulation of exocyst localization(GO:0060178)
0.3 5.2 GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.3 1.0 GO:0030578 PML body organization(GO:0030578)
0.3 2.9 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.3 1.3 GO:0006438 valyl-tRNA aminoacylation(GO:0006438)
0.3 1.3 GO:0035507 regulation of myosin-light-chain-phosphatase activity(GO:0035507)
0.3 1.3 GO:2000016 negative regulation of determination of dorsal identity(GO:2000016)
0.3 1.3 GO:2000705 regulation of dense core granule biogenesis(GO:2000705)
0.3 1.3 GO:0033566 gamma-tubulin complex localization(GO:0033566)
0.3 28.5 GO:0051028 mRNA transport(GO:0051028)
0.3 1.3 GO:0030043 actin filament fragmentation(GO:0030043)
0.3 2.5 GO:0001682 tRNA 5'-leader removal(GO:0001682)
0.3 5.2 GO:0051571 positive regulation of histone H3-K4 methylation(GO:0051571)
0.3 7.1 GO:0007019 microtubule depolymerization(GO:0007019)
0.3 2.7 GO:0033210 leptin-mediated signaling pathway(GO:0033210)
0.3 4.3 GO:0014857 regulation of skeletal muscle satellite cell proliferation(GO:0014842) regulation of skeletal muscle cell proliferation(GO:0014857)
0.3 1.8 GO:2000210 positive regulation of anoikis(GO:2000210)
0.3 1.5 GO:0018343 protein farnesylation(GO:0018343)
0.3 1.5 GO:0007296 vitellogenesis(GO:0007296)
0.3 6.7 GO:0033120 positive regulation of RNA splicing(GO:0033120)
0.3 4.0 GO:0046599 regulation of centriole replication(GO:0046599)
0.3 1.7 GO:0071394 cellular response to testosterone stimulus(GO:0071394)
0.3 2.3 GO:0097428 protein maturation by iron-sulfur cluster transfer(GO:0097428)
0.3 1.4 GO:1902416 positive regulation of mRNA binding(GO:1902416) positive regulation of RNA binding(GO:1905216)
0.3 0.9 GO:0072566 chemokine (C-X-C motif) ligand 1 production(GO:0072566) regulation of chemokine (C-X-C motif) ligand 1 production(GO:2000338)
0.3 0.9 GO:0051388 positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388)
0.3 3.7 GO:0018027 peptidyl-lysine dimethylation(GO:0018027)
0.3 2.3 GO:0016191 synaptic vesicle uncoating(GO:0016191)
0.3 0.8 GO:0032510 endosome to lysosome transport via multivesicular body sorting pathway(GO:0032510)
0.3 17.4 GO:0000245 spliceosomal complex assembly(GO:0000245)
0.3 1.1 GO:0046351 disaccharide biosynthetic process(GO:0046351)
0.3 15.1 GO:0006446 regulation of translational initiation(GO:0006446)
0.3 1.6 GO:0045653 negative regulation of megakaryocyte differentiation(GO:0045653)
0.3 0.8 GO:0009955 adaxial/abaxial pattern specification(GO:0009955) regulation of adaxial/abaxial pattern formation(GO:2000011)
0.3 10.1 GO:2000369 regulation of clathrin-mediated endocytosis(GO:2000369)
0.3 1.1 GO:1902528 regulation of protein linear polyubiquitination(GO:1902528) positive regulation of protein linear polyubiquitination(GO:1902530)
0.3 5.5 GO:0032968 positive regulation of transcription elongation from RNA polymerase II promoter(GO:0032968)
0.3 2.1 GO:0071883 activation of MAPK activity by adrenergic receptor signaling pathway(GO:0071883)
0.3 3.1 GO:0021785 branchiomotor neuron axon guidance(GO:0021785)
0.3 2.1 GO:1903599 positive regulation of mitophagy(GO:1903599)
0.3 4.9 GO:1902083 negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.3 1.8 GO:0071428 rRNA-containing ribonucleoprotein complex export from nucleus(GO:0071428)
0.2 1.0 GO:0009106 lipoate metabolic process(GO:0009106)
0.2 2.0 GO:0015727 lactate transport(GO:0015727) lactate transmembrane transport(GO:0035873) plasma membrane lactate transport(GO:0035879)
0.2 0.7 GO:1901074 regulation of engulfment of apoptotic cell(GO:1901074)
0.2 7.8 GO:2000144 positive regulation of DNA-templated transcription, initiation(GO:2000144)
0.2 3.4 GO:0090435 protein localization to nuclear envelope(GO:0090435)
0.2 1.7 GO:0080009 mRNA methylation(GO:0080009)
0.2 1.9 GO:0060315 negative regulation of ryanodine-sensitive calcium-release channel activity(GO:0060315)
0.2 2.4 GO:0010824 regulation of centrosome duplication(GO:0010824)
0.2 1.9 GO:0061718 NADH regeneration(GO:0006735) canonical glycolysis(GO:0061621) glucose catabolic process to pyruvate(GO:0061718)
0.2 12.0 GO:0042273 ribosomal large subunit biogenesis(GO:0042273)
0.2 4.1 GO:0007342 fusion of sperm to egg plasma membrane(GO:0007342)
0.2 0.9 GO:1901491 negative regulation of lymphangiogenesis(GO:1901491)
0.2 0.2 GO:1904742 regulation of telomeric DNA binding(GO:1904742)
0.2 4.5 GO:0032211 negative regulation of telomere maintenance via telomerase(GO:0032211)
0.2 11.5 GO:0006414 translational elongation(GO:0006414)
0.2 3.4 GO:0043117 positive regulation of vascular permeability(GO:0043117)
0.2 2.7 GO:0006379 mRNA cleavage(GO:0006379)
0.2 3.2 GO:0006337 nucleosome disassembly(GO:0006337) protein-DNA complex disassembly(GO:0032986)
0.2 2.0 GO:1901407 regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901407)
0.2 1.6 GO:0007182 common-partner SMAD protein phosphorylation(GO:0007182)
0.2 1.8 GO:0001833 inner cell mass cell proliferation(GO:0001833)
0.2 2.2 GO:0051683 establishment of Golgi localization(GO:0051683)
0.2 41.1 GO:0000398 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile(GO:0000377) mRNA splicing, via spliceosome(GO:0000398)
0.2 0.4 GO:2001200 positive regulation of dendritic cell differentiation(GO:2001200)
0.2 1.5 GO:0007144 female meiosis I(GO:0007144)
0.2 1.9 GO:0098728 germ-line stem cell division(GO:0042078) male germ-line stem cell asymmetric division(GO:0048133) germline stem cell asymmetric division(GO:0098728)
0.2 0.6 GO:0033615 mitochondrial proton-transporting ATP synthase complex assembly(GO:0033615)
0.2 2.8 GO:0051694 pointed-end actin filament capping(GO:0051694)
0.2 1.1 GO:2000584 platelet-derived growth factor receptor-alpha signaling pathway(GO:0035790) regulation of platelet-derived growth factor receptor-alpha signaling pathway(GO:2000583) negative regulation of platelet-derived growth factor receptor-alpha signaling pathway(GO:2000584)
0.2 6.0 GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462)
0.2 3.5 GO:1904778 regulation of protein localization to cell cortex(GO:1904776) positive regulation of protein localization to cell cortex(GO:1904778)
0.2 1.2 GO:0060708 spongiotrophoblast differentiation(GO:0060708)
0.2 0.8 GO:1902268 negative regulation of polyamine transmembrane transport(GO:1902268)
0.2 3.0 GO:0071803 positive regulation of podosome assembly(GO:0071803)
0.2 0.6 GO:0060385 axonogenesis involved in innervation(GO:0060385)
0.2 1.4 GO:0031440 regulation of mRNA 3'-end processing(GO:0031440)
0.2 0.8 GO:0021812 neuronal-glial interaction involved in cerebral cortex radial glia guided migration(GO:0021812)
0.2 1.2 GO:0008616 queuosine biosynthetic process(GO:0008616) queuosine metabolic process(GO:0046116)
0.2 1.0 GO:0044565 dendritic cell proliferation(GO:0044565)
0.2 0.8 GO:0051586 positive regulation of neurotransmitter uptake(GO:0051582) positive regulation of dopamine uptake involved in synaptic transmission(GO:0051586) positive regulation of catecholamine uptake involved in synaptic transmission(GO:0051944)
0.2 2.6 GO:0071243 cellular response to arsenic-containing substance(GO:0071243)
0.2 2.8 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.2 1.1 GO:0001927 exocyst assembly(GO:0001927)
0.2 1.7 GO:0033147 negative regulation of intracellular estrogen receptor signaling pathway(GO:0033147)
0.2 1.7 GO:0038203 TORC2 signaling(GO:0038203)
0.2 6.0 GO:1900027 regulation of ruffle assembly(GO:1900027)
0.2 1.8 GO:0010804 negative regulation of tumor necrosis factor-mediated signaling pathway(GO:0010804)
0.2 3.4 GO:0040001 establishment of mitotic spindle localization(GO:0040001)
0.2 0.7 GO:0036151 phosphatidylcholine acyl-chain remodeling(GO:0036151)
0.2 3.0 GO:0035090 maintenance of apical/basal cell polarity(GO:0035090)
0.2 1.9 GO:0031666 positive regulation of lipopolysaccharide-mediated signaling pathway(GO:0031666)
0.2 2.6 GO:0043485 endosome to melanosome transport(GO:0035646) endosome to pigment granule transport(GO:0043485) pigment granule maturation(GO:0048757)
0.2 0.5 GO:0043686 co-translational protein modification(GO:0043686)
0.2 0.7 GO:0002188 translation reinitiation(GO:0002188)
0.2 0.5 GO:1902523 positive regulation of protein K63-linked ubiquitination(GO:1902523) positive regulation of protein K48-linked ubiquitination(GO:1902524) positive regulation of protein monoubiquitination(GO:1902527)
0.2 6.8 GO:2000036 regulation of stem cell population maintenance(GO:2000036)
0.2 6.5 GO:1990090 response to nerve growth factor(GO:1990089) cellular response to nerve growth factor stimulus(GO:1990090)
0.2 2.5 GO:0006614 SRP-dependent cotranslational protein targeting to membrane(GO:0006614)
0.2 2.0 GO:0018230 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.2 2.0 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.2 1.5 GO:0051152 positive regulation of smooth muscle cell differentiation(GO:0051152)
0.2 0.8 GO:0032226 positive regulation of synaptic transmission, dopaminergic(GO:0032226)
0.2 0.6 GO:1900157 regulation of bone mineralization involved in bone maturation(GO:1900157)
0.2 11.9 GO:0051225 spindle assembly(GO:0051225)
0.2 6.4 GO:0030252 growth hormone secretion(GO:0030252)
0.2 0.5 GO:0051645 Golgi localization(GO:0051645)
0.2 2.2 GO:0032516 positive regulation of phosphoprotein phosphatase activity(GO:0032516)
0.2 0.8 GO:0001920 negative regulation of receptor recycling(GO:0001920)
0.2 8.0 GO:0006367 transcription initiation from RNA polymerase II promoter(GO:0006367)
0.2 2.8 GO:0046827 positive regulation of protein export from nucleus(GO:0046827)
0.2 0.9 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
0.2 0.8 GO:0021776 smoothened signaling pathway involved in ventral spinal cord interneuron specification(GO:0021775) smoothened signaling pathway involved in spinal cord motor neuron cell fate specification(GO:0021776)
0.2 0.8 GO:0007217 tachykinin receptor signaling pathway(GO:0007217)
0.1 1.9 GO:1904424 regulation of GTP binding(GO:1904424)
0.1 0.1 GO:0015827 aromatic amino acid transport(GO:0015801) tryptophan transport(GO:0015827)
0.1 0.7 GO:0072513 positive regulation of secondary heart field cardioblast proliferation(GO:0072513)
0.1 1.5 GO:0007064 mitotic sister chromatid cohesion(GO:0007064)
0.1 4.1 GO:0048268 clathrin coat assembly(GO:0048268)
0.1 3.8 GO:0010667 negative regulation of cardiac muscle cell apoptotic process(GO:0010667)
0.1 0.9 GO:0006543 glutamine catabolic process(GO:0006543)
0.1 1.0 GO:0016266 O-glycan processing(GO:0016266)
0.1 0.4 GO:0002949 tRNA threonylcarbamoyladenosine modification(GO:0002949)
0.1 1.1 GO:0071549 response to dexamethasone(GO:0071548) cellular response to dexamethasone stimulus(GO:0071549)
0.1 3.2 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.1 0.5 GO:0010286 heat acclimation(GO:0010286)
0.1 3.5 GO:0038065 collagen-activated signaling pathway(GO:0038065)
0.1 1.1 GO:0033085 negative regulation of T cell differentiation in thymus(GO:0033085)
0.1 4.3 GO:0032008 positive regulation of TOR signaling(GO:0032008)
0.1 0.3 GO:0060434 bronchus morphogenesis(GO:0060434)
0.1 0.8 GO:0061034 olfactory bulb mitral cell layer development(GO:0061034)
0.1 1.7 GO:0007099 centriole replication(GO:0007099)
0.1 0.1 GO:2000670 positive regulation of dendritic cell apoptotic process(GO:2000670)
0.1 0.9 GO:0051697 protein delipidation(GO:0051697)
0.1 2.4 GO:0046855 inositol phosphate dephosphorylation(GO:0046855)
0.1 7.2 GO:0006413 translational initiation(GO:0006413)
0.1 4.2 GO:0048266 behavioral response to pain(GO:0048266)
0.1 0.5 GO:1902683 regulation of receptor localization to synapse(GO:1902683)
0.1 1.3 GO:0036065 fucosylation(GO:0036065)
0.1 1.0 GO:0043922 negative regulation by host of viral transcription(GO:0043922)
0.1 0.4 GO:1904719 excitatory chemical synaptic transmission(GO:0098976) positive regulation of AMPA glutamate receptor clustering(GO:1904719)
0.1 4.9 GO:0043304 regulation of mast cell activation involved in immune response(GO:0033006) regulation of mast cell degranulation(GO:0043304)
0.1 0.2 GO:0034141 positive regulation of toll-like receptor 3 signaling pathway(GO:0034141)
0.1 1.4 GO:2000270 negative regulation of fibroblast apoptotic process(GO:2000270)
0.1 3.2 GO:0010501 RNA secondary structure unwinding(GO:0010501)
0.1 3.5 GO:0034314 Arp2/3 complex-mediated actin nucleation(GO:0034314)
0.1 0.8 GO:0019254 carnitine metabolic process, CoA-linked(GO:0019254)
0.1 0.3 GO:0021508 floor plate formation(GO:0021508)
0.1 1.0 GO:0021800 cerebral cortex tangential migration(GO:0021800) anterior commissure morphogenesis(GO:0021960)
0.1 0.8 GO:2000601 positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.1 5.1 GO:0010718 positive regulation of epithelial to mesenchymal transition(GO:0010718)
0.1 1.6 GO:0006654 phosphatidic acid biosynthetic process(GO:0006654)
0.1 1.2 GO:0060017 parathyroid gland development(GO:0060017)
0.1 0.2 GO:0010387 COP9 signalosome assembly(GO:0010387)
0.1 1.8 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.1 8.5 GO:0000079 regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0000079)
0.1 1.4 GO:0005980 glycogen catabolic process(GO:0005980) glucan catabolic process(GO:0009251) cellular polysaccharide catabolic process(GO:0044247)
0.1 0.5 GO:0035948 positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter(GO:0035948)
0.1 3.9 GO:0031648 protein destabilization(GO:0031648)
0.1 1.4 GO:0016578 histone deubiquitination(GO:0016578)
0.1 0.7 GO:0035457 cellular response to interferon-alpha(GO:0035457)
0.1 2.1 GO:0097264 self proteolysis(GO:0097264)
0.1 1.4 GO:0006824 cobalt ion transport(GO:0006824)
0.1 0.5 GO:0098887 modification of dendritic spine(GO:0098886) neurotransmitter receptor transport, endosome to postsynaptic membrane(GO:0098887)
0.1 4.3 GO:0061640 cytoskeleton-dependent cytokinesis(GO:0061640)
0.1 0.7 GO:0072711 cellular response to hydroxyurea(GO:0072711)
0.1 2.0 GO:0010591 regulation of lamellipodium assembly(GO:0010591)
0.1 3.1 GO:0071470 cellular response to osmotic stress(GO:0071470)
0.1 0.7 GO:0010701 positive regulation of norepinephrine secretion(GO:0010701)
0.1 4.4 GO:0010596 negative regulation of endothelial cell migration(GO:0010596)
0.1 1.0 GO:2000467 positive regulation of glycogen (starch) synthase activity(GO:2000467)
0.1 1.2 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.1 1.2 GO:0090190 positive regulation of branching involved in ureteric bud morphogenesis(GO:0090190)
0.1 1.4 GO:0031571 mitotic G1 DNA damage checkpoint(GO:0031571)
0.1 11.2 GO:0008380 RNA splicing(GO:0008380)
0.1 1.0 GO:0002318 myeloid progenitor cell differentiation(GO:0002318)
0.1 2.1 GO:0045116 protein neddylation(GO:0045116)
0.1 0.8 GO:0031584 activation of phospholipase D activity(GO:0031584)
0.1 0.5 GO:0008295 spermidine biosynthetic process(GO:0008295)
0.1 0.3 GO:0044154 histone H3-K14 acetylation(GO:0044154)
0.1 0.4 GO:0018242 protein O-linked glycosylation via serine(GO:0018242)
0.1 1.5 GO:0071786 endoplasmic reticulum tubular network organization(GO:0071786)
0.1 0.7 GO:0018344 protein geranylgeranylation(GO:0018344)
0.1 0.6 GO:0006398 mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.1 0.4 GO:0014886 transition between slow and fast fiber(GO:0014886)
0.1 1.3 GO:0051457 maintenance of protein location in nucleus(GO:0051457)
0.1 1.8 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.1 0.6 GO:0071763 nuclear membrane organization(GO:0071763)
0.1 4.5 GO:0035176 social behavior(GO:0035176) intraspecies interaction between organisms(GO:0051703)
0.1 0.6 GO:0031937 positive regulation of chromatin silencing(GO:0031937)
0.1 1.4 GO:0098927 early endosome to late endosome transport(GO:0045022) vesicle-mediated transport between endosomal compartments(GO:0098927)
0.1 1.3 GO:0046856 phosphatidylinositol dephosphorylation(GO:0046856)
0.1 0.6 GO:2000051 negative regulation of non-canonical Wnt signaling pathway(GO:2000051)
0.1 0.2 GO:0043504 mitochondrial DNA repair(GO:0043504)
0.1 3.3 GO:2000179 positive regulation of neural precursor cell proliferation(GO:2000179)
0.1 2.6 GO:1903963 arachidonic acid secretion(GO:0050482) arachidonate transport(GO:1903963)
0.1 1.0 GO:0048308 organelle inheritance(GO:0048308)
0.1 0.8 GO:0006346 methylation-dependent chromatin silencing(GO:0006346)
0.1 0.8 GO:0035871 protein K11-linked deubiquitination(GO:0035871)
0.1 0.3 GO:0030538 embryonic genitalia morphogenesis(GO:0030538)
0.1 1.6 GO:0071260 cellular response to mechanical stimulus(GO:0071260)
0.1 1.9 GO:1903779 regulation of cardiac conduction(GO:1903779)
0.1 2.3 GO:0040015 negative regulation of multicellular organism growth(GO:0040015)
0.1 5.4 GO:1903955 positive regulation of protein targeting to mitochondrion(GO:1903955)
0.1 1.2 GO:0031100 organ regeneration(GO:0031100)
0.1 0.3 GO:1903715 regulation of aerobic respiration(GO:1903715)
0.1 1.9 GO:0017145 stem cell division(GO:0017145)
0.1 1.2 GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
0.1 5.3 GO:0050982 detection of mechanical stimulus(GO:0050982)
0.1 0.5 GO:1901621 negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:1901621)
0.1 0.8 GO:0071578 zinc II ion transmembrane import(GO:0071578)
0.1 0.2 GO:0006244 pyrimidine nucleotide catabolic process(GO:0006244) pyrimidine deoxyribonucleotide catabolic process(GO:0009223)
0.1 0.2 GO:0097032 respiratory chain complex II assembly(GO:0034552) mitochondrial respiratory chain complex II assembly(GO:0034553) mitochondrial respiratory chain complex II biogenesis(GO:0097032)
0.1 0.6 GO:0036444 calcium ion transmembrane import into mitochondrion(GO:0036444)
0.1 0.8 GO:0006516 glycoprotein catabolic process(GO:0006516)
0.1 0.7 GO:0015809 arginine transport(GO:0015809)
0.1 3.9 GO:0015914 phospholipid transport(GO:0015914)
0.1 0.4 GO:0097035 regulation of membrane lipid distribution(GO:0097035)
0.1 0.6 GO:0015074 DNA integration(GO:0015074)
0.1 0.3 GO:0035815 vein smooth muscle contraction(GO:0014826) positive regulation of renal sodium excretion(GO:0035815) positive regulation of penile erection(GO:0060406)
0.1 1.9 GO:0032469 endoplasmic reticulum calcium ion homeostasis(GO:0032469)
0.1 0.2 GO:0032053 ciliary basal body organization(GO:0032053)
0.1 0.3 GO:0033262 regulation of nuclear cell cycle DNA replication(GO:0033262)
0.1 0.7 GO:0035493 SNARE complex assembly(GO:0035493)
0.0 0.8 GO:0006044 N-acetylglucosamine metabolic process(GO:0006044)
0.0 0.9 GO:0030262 apoptotic nuclear changes(GO:0030262)
0.0 4.3 GO:0046546 male gonad development(GO:0008584) development of primary male sexual characteristics(GO:0046546)
0.0 0.8 GO:0007603 phototransduction, visible light(GO:0007603)
0.0 1.1 GO:0051865 protein autoubiquitination(GO:0051865)
0.0 3.2 GO:0006364 rRNA processing(GO:0006364)
0.0 1.2 GO:1900048 positive regulation of blood coagulation(GO:0030194) positive regulation of hemostasis(GO:1900048)
0.0 0.6 GO:0046007 negative regulation of activated T cell proliferation(GO:0046007)
0.0 0.8 GO:0046839 phospholipid dephosphorylation(GO:0046839)
0.0 0.6 GO:0070886 positive regulation of calcineurin-NFAT signaling cascade(GO:0070886)
0.0 2.1 GO:0071482 cellular response to light stimulus(GO:0071482)
0.0 0.1 GO:0022028 tangential migration from the subventricular zone to the olfactory bulb(GO:0022028)
0.0 1.1 GO:0016601 Rac protein signal transduction(GO:0016601)
0.0 1.5 GO:0045739 positive regulation of DNA repair(GO:0045739)
0.0 0.6 GO:0043666 regulation of phosphoprotein phosphatase activity(GO:0043666)
0.0 0.7 GO:0007250 activation of NF-kappaB-inducing kinase activity(GO:0007250)
0.0 1.5 GO:0051893 regulation of focal adhesion assembly(GO:0051893) regulation of cell-substrate junction assembly(GO:0090109)
0.0 0.3 GO:0070673 response to interleukin-18(GO:0070673)
0.0 0.3 GO:0090520 sphingolipid mediated signaling pathway(GO:0090520)
0.0 0.4 GO:0051310 metaphase plate congression(GO:0051310)
0.0 1.6 GO:0042755 eating behavior(GO:0042755)
0.0 2.6 GO:0042439 ethanolamine-containing compound metabolic process(GO:0042439)
0.0 0.1 GO:0006983 ER overload response(GO:0006983)
0.0 0.4 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.0 0.4 GO:0090043 regulation of tubulin deacetylation(GO:0090043)
0.0 0.8 GO:2000398 regulation of T cell differentiation in thymus(GO:0033081) regulation of thymocyte aggregation(GO:2000398)
0.0 0.9 GO:0070979 protein K11-linked ubiquitination(GO:0070979)
0.0 0.8 GO:0040019 positive regulation of embryonic development(GO:0040019)
0.0 0.4 GO:0021995 anterior neuropore closure(GO:0021506) neuropore closure(GO:0021995)
0.0 0.1 GO:0034421 post-translational protein acetylation(GO:0034421)
0.0 0.3 GO:0002051 osteoblast fate commitment(GO:0002051)
0.0 0.9 GO:0030488 tRNA methylation(GO:0030488)
0.0 2.1 GO:0031497 chromatin assembly(GO:0031497)
0.0 1.3 GO:0014911 positive regulation of smooth muscle cell migration(GO:0014911)
0.0 0.1 GO:0043928 exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay(GO:0043928)
0.0 0.9 GO:0051497 negative regulation of stress fiber assembly(GO:0051497)
0.0 0.5 GO:0071157 negative regulation of cell cycle arrest(GO:0071157)
0.0 1.3 GO:0019933 cAMP-mediated signaling(GO:0019933)
0.0 0.3 GO:0008298 intracellular mRNA localization(GO:0008298)
0.0 0.2 GO:0090161 Golgi ribbon formation(GO:0090161)
0.0 1.5 GO:0048247 lymphocyte chemotaxis(GO:0048247)
0.0 0.0 GO:0001560 regulation of cell growth by extracellular stimulus(GO:0001560)
0.0 0.7 GO:0060416 response to growth hormone(GO:0060416)
0.0 0.8 GO:0071391 cellular response to estrogen stimulus(GO:0071391)
0.0 0.1 GO:0019287 isopentenyl diphosphate biosynthetic process, mevalonate pathway(GO:0019287)
0.0 0.5 GO:0032780 negative regulation of ATPase activity(GO:0032780)
0.0 0.1 GO:0006283 transcription-coupled nucleotide-excision repair(GO:0006283)
0.0 0.1 GO:0032897 negative regulation of viral transcription(GO:0032897)
0.0 0.8 GO:0032272 negative regulation of protein polymerization(GO:0032272)
0.0 0.1 GO:1903003 positive regulation of protein deubiquitination(GO:1903003)
0.0 0.4 GO:0018345 protein palmitoylation(GO:0018345)
0.0 0.2 GO:1901142 insulin metabolic process(GO:1901142)
0.0 1.3 GO:0032410 negative regulation of transporter activity(GO:0032410)
0.0 0.3 GO:0070884 regulation of calcineurin-NFAT signaling cascade(GO:0070884)
0.0 0.4 GO:0060216 definitive hemopoiesis(GO:0060216)
0.0 0.1 GO:0018211 protein C-linked glycosylation(GO:0018103) peptidyl-tryptophan modification(GO:0018211) protein C-linked glycosylation via tryptophan(GO:0018317) protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan(GO:0018406)
0.0 1.4 GO:1902476 chloride transmembrane transport(GO:1902476)
0.0 0.7 GO:0042149 cellular response to glucose starvation(GO:0042149)
0.0 1.7 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.0 0.2 GO:0046541 saliva secretion(GO:0046541)
0.0 1.1 GO:0032755 positive regulation of interleukin-6 production(GO:0032755)
0.0 0.2 GO:0001953 negative regulation of cell-matrix adhesion(GO:0001953)
0.0 0.7 GO:0030199 collagen fibril organization(GO:0030199)
0.0 0.8 GO:0051057 positive regulation of small GTPase mediated signal transduction(GO:0051057)
0.0 0.1 GO:0006384 transcription initiation from RNA polymerase III promoter(GO:0006384)
0.0 0.3 GO:0046686 response to cadmium ion(GO:0046686)
0.0 0.5 GO:0042254 ribosome biogenesis(GO:0042254)
0.0 0.2 GO:0032482 Rab protein signal transduction(GO:0032482)
0.0 0.6 GO:0001895 retina homeostasis(GO:0001895)
0.0 2.2 GO:0000209 protein polyubiquitination(GO:0000209)
0.0 0.2 GO:0048280 vesicle fusion with Golgi apparatus(GO:0048280)
0.0 0.2 GO:0040023 nuclear migration(GO:0007097) establishment of nucleus localization(GO:0040023)
0.0 0.1 GO:0030579 ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.0 0.7 GO:0003014 renal system process(GO:0003014)
0.0 0.3 GO:0010800 positive regulation of peptidyl-threonine phosphorylation(GO:0010800)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
4.7 28.2 GO:0097226 sperm mitochondrial sheath(GO:0097226)
3.1 9.3 GO:0005673 transcription factor TFIIE complex(GO:0005673)
2.9 14.3 GO:0000799 nuclear condensin complex(GO:0000799)
2.6 7.9 GO:0000818 nuclear MIS12/MIND complex(GO:0000818)
2.4 7.3 GO:0031074 nucleocytoplasmic shuttling complex(GO:0031074)
2.3 7.0 GO:0043614 multi-eIF complex(GO:0043614)
2.2 11.1 GO:0016602 CCAAT-binding factor complex(GO:0016602)
2.2 8.7 GO:0042585 germinal vesicle(GO:0042585)
1.9 7.6 GO:0000942 condensed nuclear chromosome outer kinetochore(GO:0000942)
1.8 5.3 GO:0097135 cyclin E2-CDK2 complex(GO:0097135)
1.7 11.8 GO:0005850 eukaryotic translation initiation factor 2 complex(GO:0005850)
1.7 11.6 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
1.6 6.6 GO:0071821 FANCM-MHF complex(GO:0071821)
1.5 6.1 GO:0090661 box H/ACA telomerase RNP complex(GO:0090661)
1.5 10.3 GO:0031298 replication fork protection complex(GO:0031298)
1.4 4.3 GO:0016939 kinesin II complex(GO:0016939)
1.4 15.0 GO:0031415 NatA complex(GO:0031415)
1.3 4.0 GO:1990879 CST complex(GO:1990879)
1.3 14.3 GO:0044613 nuclear pore central transport channel(GO:0044613)
1.3 9.0 GO:0000796 condensin complex(GO:0000796)
1.3 3.8 GO:0005760 gamma DNA polymerase complex(GO:0005760)
1.3 12.7 GO:0001940 male pronucleus(GO:0001940)
1.3 8.8 GO:0000798 nuclear cohesin complex(GO:0000798)
1.2 30.6 GO:0035686 sperm fibrous sheath(GO:0035686)
1.2 6.0 GO:0031510 SUMO activating enzyme complex(GO:0031510)
1.2 7.2 GO:0071458 integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458) integral component of lumenal side of endoplasmic reticulum membrane(GO:0071556) lumenal side of endoplasmic reticulum membrane(GO:0098553)
1.2 9.6 GO:0005826 actomyosin contractile ring(GO:0005826)
1.2 4.8 GO:1990037 Lewy body core(GO:1990037)
1.2 13.0 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
1.2 9.4 GO:0001652 granular component(GO:0001652)
1.1 7.8 GO:0070522 ERCC4-ERCC1 complex(GO:0070522)
1.1 5.3 GO:0008278 cohesin complex(GO:0008278)
1.0 1.0 GO:0071001 U4/U6 snRNP(GO:0071001)
1.0 10.9 GO:0005664 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
1.0 14.7 GO:0008290 F-actin capping protein complex(GO:0008290)
1.0 9.8 GO:0042382 paraspeckles(GO:0042382)
1.0 6.7 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.9 4.7 GO:0035189 Rb-E2F complex(GO:0035189)
0.9 5.5 GO:0097149 centralspindlin complex(GO:0097149)
0.9 15.1 GO:0000974 Prp19 complex(GO:0000974)
0.8 3.3 GO:1990298 mitotic checkpoint complex(GO:0033597) bub1-bub3 complex(GO:1990298)
0.8 6.6 GO:0071204 histone pre-mRNA 3'end processing complex(GO:0071204)
0.8 5.7 GO:0098536 deuterosome(GO:0098536)
0.8 1.6 GO:0097504 Gemini of coiled bodies(GO:0097504)
0.8 3.3 GO:0098833 presynaptic endocytic zone(GO:0098833) presynaptic endocytic zone membrane(GO:0098835)
0.8 7.3 GO:0036449 microtubule minus-end(GO:0036449)
0.8 10.5 GO:0031080 nuclear pore outer ring(GO:0031080)
0.8 2.4 GO:0055087 Ski complex(GO:0055087)
0.7 9.0 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
0.7 3.6 GO:0032389 MutLalpha complex(GO:0032389)
0.7 10.6 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.7 4.2 GO:0031314 extrinsic component of mitochondrial inner membrane(GO:0031314)
0.7 9.8 GO:0005688 U6 snRNP(GO:0005688)
0.7 2.8 GO:0070937 CRD-mediated mRNA stability complex(GO:0070937)
0.7 0.7 GO:0019034 viral replication complex(GO:0019034)
0.7 11.4 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
0.7 2.0 GO:0042643 actomyosin, actin portion(GO:0042643)
0.7 7.2 GO:0000235 astral microtubule(GO:0000235)
0.6 2.6 GO:0032021 NELF complex(GO:0032021)
0.6 1.9 GO:0020018 ciliary pocket(GO:0020016) ciliary pocket membrane(GO:0020018)
0.6 1.3 GO:0036488 CHOP-C/EBP complex(GO:0036488)
0.6 6.3 GO:0031390 Ctf18 RFC-like complex(GO:0031390)
0.6 1.9 GO:0005712 chiasma(GO:0005712)
0.6 1.9 GO:1990666 PCSK9-LDLR complex(GO:1990666) PCSK9-AnxA2 complex(GO:1990667)
0.6 1.8 GO:1990023 mitotic spindle midzone(GO:1990023)
0.6 10.4 GO:0000346 transcription export complex(GO:0000346)
0.6 13.3 GO:0031011 Ino80 complex(GO:0031011)
0.6 0.6 GO:0000110 nucleotide-excision repair factor 1 complex(GO:0000110)
0.6 7.1 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.6 1.2 GO:0046540 U4/U6 x U5 tri-snRNP complex(GO:0046540)
0.6 6.5 GO:0000783 telomere cap complex(GO:0000782) nuclear telomere cap complex(GO:0000783)
0.6 85.0 GO:0000776 kinetochore(GO:0000776)
0.6 4.1 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.6 3.9 GO:0036194 muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195)
0.6 2.2 GO:0035061 interchromatin granule(GO:0035061)
0.6 3.9 GO:0005655 nucleolar ribonuclease P complex(GO:0005655)
0.5 1.6 GO:0009328 phenylalanine-tRNA ligase complex(GO:0009328)
0.5 3.8 GO:0072357 PTW/PP1 phosphatase complex(GO:0072357)
0.5 10.4 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.5 3.1 GO:0043527 tRNA methyltransferase complex(GO:0043527)
0.5 3.1 GO:0035985 senescence-associated heterochromatin focus(GO:0035985)
0.5 2.6 GO:0001939 female pronucleus(GO:0001939)
0.5 10.9 GO:0071564 npBAF complex(GO:0071564)
0.5 1.5 GO:0005965 protein farnesyltransferase complex(GO:0005965)
0.5 5.9 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.5 2.9 GO:0031523 Myb complex(GO:0031523)
0.5 2.4 GO:0097165 nuclear stress granule(GO:0097165)
0.5 7.7 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.5 1.4 GO:0031372 UBC13-MMS2 complex(GO:0031372)
0.5 4.3 GO:0005786 signal recognition particle, endoplasmic reticulum targeting(GO:0005786)
0.5 6.6 GO:0090544 BAF-type complex(GO:0090544)
0.5 8.8 GO:0097431 mitotic spindle pole(GO:0097431)
0.5 3.2 GO:0030289 protein phosphatase 4 complex(GO:0030289)
0.5 2.3 GO:0001651 dense fibrillar component(GO:0001651)
0.5 5.0 GO:0072669 tRNA-splicing ligase complex(GO:0072669)
0.5 2.7 GO:0031414 N-terminal protein acetyltransferase complex(GO:0031414)
0.5 3.2 GO:0071014 post-mRNA release spliceosomal complex(GO:0071014)
0.4 1.3 GO:0000125 PCAF complex(GO:0000125)
0.4 7.0 GO:0044754 autolysosome(GO:0044754)
0.4 5.6 GO:0044666 MLL3/4 complex(GO:0044666)
0.4 6.0 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.4 4.5 GO:0031931 TORC1 complex(GO:0031931)
0.4 85.7 GO:0005681 spliceosomal complex(GO:0005681)
0.4 5.0 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.4 1.2 GO:0030681 ribonuclease P complex(GO:0030677) multimeric ribonuclease P complex(GO:0030681)
0.4 5.8 GO:0016580 Sin3 complex(GO:0016580)
0.4 6.9 GO:0005832 chaperonin-containing T-complex(GO:0005832)
0.4 0.7 GO:0031933 telomeric heterochromatin(GO:0031933)
0.4 29.4 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.4 4.1 GO:0016272 prefoldin complex(GO:0016272)
0.4 3.3 GO:0070436 Grb2-EGFR complex(GO:0070436)
0.4 1.8 GO:0005851 eukaryotic translation initiation factor 2B complex(GO:0005851)
0.4 9.9 GO:0071339 MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.4 2.2 GO:0000214 tRNA-intron endonuclease complex(GO:0000214)
0.4 13.3 GO:0030992 intraciliary transport particle B(GO:0030992)
0.3 0.7 GO:0070992 translation initiation complex(GO:0070992)
0.3 3.0 GO:0070652 HAUS complex(GO:0070652)
0.3 3.7 GO:0005677 chromatin silencing complex(GO:0005677)
0.3 7.6 GO:0043189 NuA4 histone acetyltransferase complex(GO:0035267) H4/H2A histone acetyltransferase complex(GO:0043189) H4 histone acetyltransferase complex(GO:1902562)
0.3 1.0 GO:0043159 acrosomal matrix(GO:0043159)
0.3 5.3 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.3 4.6 GO:0030126 COPI vesicle coat(GO:0030126)
0.3 9.0 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.3 2.2 GO:0031467 Cul7-RING ubiquitin ligase complex(GO:0031467)
0.3 5.1 GO:0031616 spindle pole centrosome(GO:0031616)
0.3 22.2 GO:0005643 nuclear pore(GO:0005643)
0.3 8.0 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.3 2.4 GO:0097422 tubular endosome(GO:0097422)
0.3 1.5 GO:0072487 MSL complex(GO:0072487)
0.3 2.4 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.3 2.0 GO:0070695 FHF complex(GO:0070695)
0.3 4.9 GO:0005641 nuclear envelope lumen(GO:0005641)
0.3 23.0 GO:0000775 chromosome, centromeric region(GO:0000775)
0.3 4.2 GO:0005639 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229)
0.3 5.3 GO:0032039 integrator complex(GO:0032039)
0.3 4.2 GO:0042555 MCM complex(GO:0042555)
0.3 19.5 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.3 5.1 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.3 3.0 GO:0070531 BRCA1-A complex(GO:0070531)
0.3 0.8 GO:0005607 laminin-2 complex(GO:0005607)
0.3 1.6 GO:0032437 cuticular plate(GO:0032437)
0.3 4.3 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.3 0.8 GO:0097550 transcriptional preinitiation complex(GO:0097550)
0.3 17.2 GO:0015934 large ribosomal subunit(GO:0015934)
0.3 2.0 GO:0071986 Ragulator complex(GO:0071986)
0.2 3.5 GO:0001931 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.2 1.7 GO:0036396 MIS complex(GO:0036396)
0.2 2.2 GO:0034719 SMN-Sm protein complex(GO:0034719)
0.2 2.4 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.2 4.5 GO:0000242 pericentriolar material(GO:0000242)
0.2 6.9 GO:0005669 transcription factor TFIID complex(GO:0005669)
0.2 14.8 GO:0045171 intercellular bridge(GO:0045171)
0.2 1.7 GO:0005827 polar microtubule(GO:0005827)
0.2 10.0 GO:0030686 90S preribosome(GO:0030686)
0.2 1.4 GO:0010369 chromocenter(GO:0010369)
0.2 4.4 GO:0032593 insulin-responsive compartment(GO:0032593)
0.2 5.7 GO:0005680 anaphase-promoting complex(GO:0005680)
0.2 12.3 GO:0005844 polysome(GO:0005844)
0.2 2.1 GO:1990357 terminal web(GO:1990357)
0.2 7.9 GO:0005720 nuclear heterochromatin(GO:0005720)
0.2 3.1 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.2 5.4 GO:0005876 spindle microtubule(GO:0005876)
0.2 12.1 GO:0000784 nuclear chromosome, telomeric region(GO:0000784)
0.2 17.3 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.2 1.1 GO:0005662 DNA replication factor A complex(GO:0005662)
0.2 1.6 GO:0033061 DNA recombinase mediator complex(GO:0033061)
0.2 2.0 GO:0016442 RISC complex(GO:0016442) RNAi effector complex(GO:0031332)
0.2 3.0 GO:0000137 Golgi cis cisterna(GO:0000137)
0.2 1.0 GO:0030121 AP-1 adaptor complex(GO:0030121)
0.2 1.0 GO:0097425 smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425)
0.2 0.8 GO:0043625 delta DNA polymerase complex(GO:0043625)
0.2 8.8 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.2 0.6 GO:0098837 postsynaptic recycling endosome(GO:0098837)
0.2 0.7 GO:0031680 G-protein beta/gamma-subunit complex(GO:0031680)
0.2 1.2 GO:0030915 Smc5-Smc6 complex(GO:0030915)
0.2 2.0 GO:0090543 Flemming body(GO:0090543)
0.2 3.0 GO:0042582 primary lysosome(GO:0005766) azurophil granule(GO:0042582)
0.2 2.6 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.2 1.7 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.2 4.1 GO:0005637 nuclear inner membrane(GO:0005637)
0.2 2.0 GO:0031597 cytosolic proteasome complex(GO:0031597)
0.2 1.7 GO:0000815 ESCRT III complex(GO:0000815)
0.2 2.9 GO:0030684 preribosome(GO:0030684)
0.2 2.7 GO:0036038 MKS complex(GO:0036038)
0.1 6.1 GO:0030131 clathrin adaptor complex(GO:0030131)
0.1 2.4 GO:0070938 contractile ring(GO:0070938)
0.1 1.7 GO:0031258 lamellipodium membrane(GO:0031258)
0.1 1.1 GO:0016600 flotillin complex(GO:0016600)
0.1 1.4 GO:0008024 cyclin/CDK positive transcription elongation factor complex(GO:0008024)
0.1 0.7 GO:0070032 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032) synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex(GO:0070033)
0.1 3.4 GO:0000145 exocyst(GO:0000145)
0.1 1.0 GO:0033010 paranodal junction(GO:0033010)
0.1 15.5 GO:0017053 transcriptional repressor complex(GO:0017053)
0.1 1.6 GO:0000124 SAGA complex(GO:0000124)
0.1 0.7 GO:0005968 Rab-protein geranylgeranyltransferase complex(GO:0005968)
0.1 1.0 GO:0033503 HULC complex(GO:0033503)
0.1 1.0 GO:0010009 cytoplasmic side of endosome membrane(GO:0010009)
0.1 0.8 GO:0005587 collagen type IV trimer(GO:0005587) network-forming collagen trimer(GO:0098642) collagen network(GO:0098645) basement membrane collagen trimer(GO:0098651)
0.1 4.5 GO:0002102 podosome(GO:0002102)
0.1 1.5 GO:0008385 IkappaB kinase complex(GO:0008385)
0.1 1.1 GO:0000923 equatorial microtubule organizing center(GO:0000923)
0.1 7.2 GO:0016605 PML body(GO:0016605)
0.1 2.0 GO:0031143 pseudopodium(GO:0031143)
0.1 5.4 GO:0031941 filamentous actin(GO:0031941)
0.1 0.7 GO:0002177 manchette(GO:0002177)
0.1 5.5 GO:0005871 kinesin complex(GO:0005871)
0.1 1.8 GO:0031045 dense core granule(GO:0031045)
0.1 2.6 GO:0015030 Cajal body(GO:0015030)
0.1 1.1 GO:0030014 CCR4-NOT complex(GO:0030014)
0.1 9.9 GO:0032587 ruffle membrane(GO:0032587)
0.1 8.4 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.1 0.9 GO:1904115 axon cytoplasm(GO:1904115)
0.1 0.7 GO:0061700 GATOR2 complex(GO:0061700)
0.1 1.1 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.1 0.4 GO:0005869 dynactin complex(GO:0005869)
0.1 0.8 GO:0045252 oxoglutarate dehydrogenase complex(GO:0045252)
0.1 0.3 GO:0005854 nascent polypeptide-associated complex(GO:0005854)
0.1 6.1 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.1 6.1 GO:0016363 nuclear matrix(GO:0016363)
0.1 0.7 GO:0031932 TORC2 complex(GO:0031932)
0.1 0.7 GO:0034518 mRNA cap binding complex(GO:0005845) RNA cap binding complex(GO:0034518)
0.1 24.6 GO:0016607 nuclear speck(GO:0016607)
0.1 0.8 GO:0034464 BBSome(GO:0034464)
0.1 3.5 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.1 0.6 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.1 2.3 GO:0016235 aggresome(GO:0016235)
0.1 0.8 GO:0031209 SCAR complex(GO:0031209)
0.1 0.8 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.1 0.4 GO:0032541 cortical endoplasmic reticulum(GO:0032541)
0.1 2.4 GO:0030863 cortical cytoskeleton(GO:0030863)
0.1 0.6 GO:0000127 transcription factor TFIIIC complex(GO:0000127)
0.1 5.9 GO:0005811 lipid particle(GO:0005811)
0.1 0.5 GO:0036513 Derlin-1 retrotranslocation complex(GO:0036513)
0.1 1.4 GO:0030665 clathrin-coated vesicle membrane(GO:0030665)
0.1 1.6 GO:0099738 cell cortex region(GO:0099738)
0.1 2.1 GO:0001772 immunological synapse(GO:0001772)
0.1 0.2 GO:0031371 ubiquitin conjugating enzyme complex(GO:0031371)
0.1 2.4 GO:0060170 ciliary membrane(GO:0060170)
0.1 5.0 GO:0016328 lateral plasma membrane(GO:0016328)
0.1 0.4 GO:0000408 EKC/KEOPS complex(GO:0000408)
0.1 1.1 GO:0005797 Golgi medial cisterna(GO:0005797)
0.1 0.9 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.0 3.3 GO:0014704 intercalated disc(GO:0014704)
0.0 19.2 GO:0045121 membrane raft(GO:0045121) membrane microdomain(GO:0098857)
0.0 0.8 GO:0043034 costamere(GO:0043034)
0.0 2.0 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.0 2.9 GO:0000502 proteasome complex(GO:0000502)
0.0 3.0 GO:0036126 sperm flagellum(GO:0036126)
0.0 0.2 GO:0071203 WASH complex(GO:0071203)
0.0 3.3 GO:0043195 terminal bouton(GO:0043195)
0.0 1.4 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 1.2 GO:0032420 stereocilium(GO:0032420)
0.0 6.6 GO:0005874 microtubule(GO:0005874)
0.0 0.8 GO:0008023 transcription elongation factor complex(GO:0008023)
0.0 0.6 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.0 0.6 GO:0030904 retromer complex(GO:0030904)
0.0 1.5 GO:0034707 chloride channel complex(GO:0034707)
0.0 1.8 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.0 0.0 GO:0034685 integrin alphav-beta6 complex(GO:0034685)
0.0 0.2 GO:0035145 exon-exon junction complex(GO:0035145)
0.0 0.2 GO:0000930 gamma-tubulin complex(GO:0000930)
0.0 0.3 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.0 0.2 GO:0035253 ciliary rootlet(GO:0035253)
0.0 0.9 GO:0043198 dendritic shaft(GO:0043198)
0.0 0.5 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.0 0.4 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.0 0.0 GO:0034657 GID complex(GO:0034657)
0.0 0.2 GO:0048770 melanosome(GO:0042470) pigment granule(GO:0048770)
0.0 0.8 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
4.0 28.2 GO:0002135 CTP binding(GO:0002135)
3.4 10.3 GO:0097100 supercoiled DNA binding(GO:0097100)
2.7 24.4 GO:0043023 ribosomal large subunit binding(GO:0043023)
2.5 7.4 GO:0047192 1-alkylglycerophosphocholine O-acetyltransferase activity(GO:0047192)
2.4 14.6 GO:0004852 uroporphyrinogen-III synthase activity(GO:0004852)
2.3 6.8 GO:0005137 interleukin-5 receptor binding(GO:0005137)
2.1 6.4 GO:0010698 acetyltransferase activator activity(GO:0010698)
2.1 15.0 GO:0044547 DNA topoisomerase binding(GO:0044547)
2.1 18.6 GO:1990189 peptide-serine-N-acetyltransferase activity(GO:1990189)
2.0 12.1 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575)
2.0 6.0 GO:0019948 SUMO activating enzyme activity(GO:0019948)
2.0 5.9 GO:0004828 serine-tRNA ligase activity(GO:0004828)
2.0 5.9 GO:0045142 triplex DNA binding(GO:0045142)
1.9 15.5 GO:0010521 telomerase inhibitor activity(GO:0010521)
1.9 5.7 GO:0097677 STAT family protein binding(GO:0097677)
1.9 11.3 GO:1990050 phosphatidic acid transporter activity(GO:1990050)
1.9 1.9 GO:0015616 DNA translocase activity(GO:0015616)
1.8 16.4 GO:1990948 ligase inhibitor activity(GO:0055104) ubiquitin ligase inhibitor activity(GO:1990948)
1.8 14.3 GO:0051425 PTB domain binding(GO:0051425)
1.7 6.7 GO:0008160 protein tyrosine phosphatase activator activity(GO:0008160)
1.6 20.9 GO:0005049 nuclear export signal receptor activity(GO:0005049)
1.6 6.2 GO:0070137 ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139)
1.5 4.5 GO:0035851 Krueppel-associated box domain binding(GO:0035851)
1.5 4.5 GO:0004471 malic enzyme activity(GO:0004470) malate dehydrogenase (decarboxylating) (NAD+) activity(GO:0004471) malate dehydrogenase (decarboxylating) (NADP+) activity(GO:0004473)
1.5 6.0 GO:0071207 histone pre-mRNA stem-loop binding(GO:0071207)
1.5 7.4 GO:0017108 5'-flap endonuclease activity(GO:0017108)
1.5 5.9 GO:0001884 pyrimidine nucleoside binding(GO:0001884)
1.5 4.4 GO:0004560 alpha-L-fucosidase activity(GO:0004560) fucosidase activity(GO:0015928)
1.4 7.2 GO:0071987 WD40-repeat domain binding(GO:0071987)
1.4 5.6 GO:1990932 5.8S rRNA binding(GO:1990932)
1.4 5.6 GO:1903136 cuprous ion binding(GO:1903136)
1.3 5.3 GO:0003883 CTP synthase activity(GO:0003883)
1.3 17.2 GO:0001055 RNA polymerase II activity(GO:0001055)
1.2 7.4 GO:0008821 crossover junction endodeoxyribonuclease activity(GO:0008821)
1.1 4.3 GO:0004711 ribosomal protein S6 kinase activity(GO:0004711)
1.1 4.3 GO:0032356 oxidized DNA binding(GO:0032356)
1.0 5.1 GO:0098809 nitrite reductase activity(GO:0098809)
1.0 11.2 GO:0070053 thrombospondin receptor activity(GO:0070053)
1.0 7.0 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.9 1.8 GO:0032138 single base insertion or deletion binding(GO:0032138)
0.9 3.6 GO:0004656 procollagen-proline 4-dioxygenase activity(GO:0004656)
0.9 2.7 GO:0070039 rRNA (guanosine-2'-O-)-methyltransferase activity(GO:0070039)
0.9 4.4 GO:0055056 D-glucose transmembrane transporter activity(GO:0055056)
0.9 1.8 GO:0070336 flap-structured DNA binding(GO:0070336)
0.9 6.1 GO:0034513 box H/ACA snoRNA binding(GO:0034513)
0.9 25.1 GO:0043295 glutathione binding(GO:0043295) oligopeptide binding(GO:1900750)
0.9 6.0 GO:0050733 RS domain binding(GO:0050733)
0.9 2.6 GO:0035614 snRNA stem-loop binding(GO:0035614)
0.8 2.5 GO:0003999 adenine binding(GO:0002055) adenine phosphoribosyltransferase activity(GO:0003999)
0.8 2.4 GO:0047756 chondroitin 4-sulfotransferase activity(GO:0047756)
0.8 5.6 GO:0043515 kinetochore binding(GO:0043515)
0.8 4.8 GO:0019211 phosphatase activator activity(GO:0019211)
0.8 1.6 GO:0016435 rRNA (guanine) methyltransferase activity(GO:0016435)
0.8 0.8 GO:0016422 mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity(GO:0016422)
0.8 3.1 GO:0008176 tRNA (guanine-N7-)-methyltransferase activity(GO:0008176)
0.8 3.9 GO:0061649 ubiquitinated histone binding(GO:0061649)
0.8 5.4 GO:0032027 myosin light chain binding(GO:0032027)
0.8 3.0 GO:0004844 uracil DNA N-glycosylase activity(GO:0004844) deaminated base DNA N-glycosylase activity(GO:0097506)
0.8 3.8 GO:0004719 protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
0.8 3.0 GO:0019237 centromeric DNA binding(GO:0019237)
0.7 2.2 GO:0003963 RNA-3'-phosphate cyclase activity(GO:0003963)
0.7 7.2 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.7 4.3 GO:0030942 endoplasmic reticulum signal peptide binding(GO:0030942)
0.7 5.0 GO:0044729 hemi-methylated DNA-binding(GO:0044729)
0.7 24.1 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.7 8.5 GO:0008097 5S rRNA binding(GO:0008097)
0.7 8.5 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.7 2.8 GO:0031208 POZ domain binding(GO:0031208)
0.7 20.2 GO:0008143 poly(A) binding(GO:0008143)
0.7 4.0 GO:0004483 mRNA (nucleoside-2'-O-)-methyltransferase activity(GO:0004483)
0.6 3.2 GO:0005143 interleukin-12 receptor binding(GO:0005143)
0.6 5.1 GO:0061676 importin-alpha family protein binding(GO:0061676)
0.6 1.9 GO:0034189 very-low-density lipoprotein particle binding(GO:0034189)
0.6 2.5 GO:0031694 alpha-2A adrenergic receptor binding(GO:0031694)
0.6 2.4 GO:0008184 glycogen phosphorylase activity(GO:0008184)
0.6 3.5 GO:0033142 progesterone receptor binding(GO:0033142)
0.6 2.3 GO:0031727 CCR2 chemokine receptor binding(GO:0031727)
0.6 1.7 GO:1904047 S-adenosyl-L-methionine binding(GO:1904047)
0.6 1.7 GO:0010385 double-stranded methylated DNA binding(GO:0010385)
0.6 2.3 GO:0004066 asparagine synthase (glutamine-hydrolyzing) activity(GO:0004066)
0.6 11.2 GO:0051011 microtubule minus-end binding(GO:0051011)
0.6 2.2 GO:0045131 pre-mRNA branch point binding(GO:0045131)
0.6 1.7 GO:0030943 mitochondrion targeting sequence binding(GO:0030943)
0.5 1.6 GO:0030621 U4 snRNA binding(GO:0030621)
0.5 7.0 GO:1990825 sequence-specific mRNA binding(GO:1990825)
0.5 8.0 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.5 2.1 GO:0042978 ornithine decarboxylase activator activity(GO:0042978)
0.5 0.5 GO:0098770 FBXO family protein binding(GO:0098770)
0.5 5.1 GO:0030267 hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267)
0.5 36.0 GO:0003743 translation initiation factor activity(GO:0003743)
0.5 6.6 GO:0035613 RNA stem-loop binding(GO:0035613)
0.5 5.0 GO:0004526 ribonuclease P activity(GO:0004526)
0.5 1.5 GO:0004660 protein farnesyltransferase activity(GO:0004660)
0.5 3.4 GO:0098519 nucleotide phosphatase activity, acting on free nucleotides(GO:0098519)
0.5 4.4 GO:0030619 U1 snRNA binding(GO:0030619)
0.5 2.9 GO:0034988 Fc-gamma receptor I complex binding(GO:0034988)
0.5 6.8 GO:0097200 cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.5 3.4 GO:0005087 Ran guanyl-nucleotide exchange factor activity(GO:0005087)
0.5 2.8 GO:0046974 histone methyltransferase activity (H3-K9 specific)(GO:0046974)
0.5 3.3 GO:0016972 thiol oxidase activity(GO:0016972)
0.5 4.2 GO:0032453 histone demethylase activity (H3-K4 specific)(GO:0032453)
0.5 7.4 GO:0003688 DNA replication origin binding(GO:0003688)
0.5 1.4 GO:0004822 isoleucine-tRNA ligase activity(GO:0004822)
0.5 1.4 GO:0004342 glucosamine-6-phosphate deaminase activity(GO:0004342)
0.5 1.8 GO:0034511 U3 snoRNA binding(GO:0034511)
0.4 2.7 GO:0035515 oxidative RNA demethylase activity(GO:0035515)
0.4 2.6 GO:0010997 anaphase-promoting complex binding(GO:0010997)
0.4 8.7 GO:0035174 histone serine kinase activity(GO:0035174)
0.4 2.1 GO:0032554 purine deoxyribonucleotide binding(GO:0032554)
0.4 2.1 GO:0004724 magnesium-dependent protein serine/threonine phosphatase activity(GO:0004724)
0.4 4.7 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
0.4 9.7 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.4 1.7 GO:0047522 13-prostaglandin reductase activity(GO:0036132) 15-oxoprostaglandin 13-oxidase activity(GO:0047522)
0.4 2.9 GO:0016018 cyclosporin A binding(GO:0016018)
0.4 6.5 GO:1990405 protein antigen binding(GO:1990405)
0.4 0.8 GO:1990269 RNA polymerase II C-terminal domain phosphoserine binding(GO:1990269)
0.4 5.6 GO:0009008 DNA-methyltransferase activity(GO:0009008)
0.4 2.0 GO:1990188 euchromatin binding(GO:1990188)
0.4 1.2 GO:0070138 isopeptidase activity(GO:0070122) ubiquitin-like protein-specific isopeptidase activity(GO:0070138) SUMO-specific isopeptidase activity(GO:0070140)
0.4 2.4 GO:0034186 apolipoprotein A-I binding(GO:0034186)
0.4 1.1 GO:0009383 rRNA (cytosine-C5-)-methyltransferase activity(GO:0009383)
0.4 1.9 GO:0070012 oligopeptidase activity(GO:0070012)
0.4 1.5 GO:0004092 carnitine O-acetyltransferase activity(GO:0004092)
0.4 3.3 GO:0016308 1-phosphatidylinositol-4-phosphate 5-kinase activity(GO:0016308)
0.4 8.3 GO:0005487 nucleocytoplasmic transporter activity(GO:0005487)
0.4 11.8 GO:0008536 Ran GTPase binding(GO:0008536)
0.4 1.8 GO:0045322 unmethylated CpG binding(GO:0045322)
0.3 1.4 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)
0.3 1.0 GO:0031826 type 2A serotonin receptor binding(GO:0031826)
0.3 5.9 GO:0001163 RNA polymerase I regulatory region sequence-specific DNA binding(GO:0001163) RNA polymerase I CORE element sequence-specific DNA binding(GO:0001164)
0.3 1.4 GO:1990460 leptin receptor binding(GO:1990460)
0.3 10.2 GO:0070840 dynein complex binding(GO:0070840)
0.3 5.4 GO:1990226 histone methyltransferase binding(GO:1990226)
0.3 1.7 GO:0004534 5'-3' exoribonuclease activity(GO:0004534)
0.3 2.6 GO:0000014 single-stranded DNA endodeoxyribonuclease activity(GO:0000014)
0.3 2.6 GO:0001515 opioid peptide activity(GO:0001515)
0.3 1.3 GO:0061628 H3K27me3 modified histone binding(GO:0061628)
0.3 0.6 GO:0008934 inositol monophosphate 1-phosphatase activity(GO:0008934) inositol monophosphate 3-phosphatase activity(GO:0052832) inositol monophosphate 4-phosphatase activity(GO:0052833) inositol monophosphate phosphatase activity(GO:0052834)
0.3 2.5 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.3 0.9 GO:0071535 RING-like zinc finger domain binding(GO:0071535)
0.3 1.5 GO:0070548 L-glutamine aminotransferase activity(GO:0070548)
0.3 0.9 GO:0016426 tRNA (adenine) methyltransferase activity(GO:0016426)
0.3 2.1 GO:0061665 SUMO ligase activity(GO:0061665)
0.3 2.7 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873)
0.3 1.5 GO:0004809 tRNA (guanine-N2-)-methyltransferase activity(GO:0004809)
0.3 20.7 GO:0035064 methylated histone binding(GO:0035064)
0.3 11.0 GO:0017091 AU-rich element binding(GO:0017091)
0.3 0.9 GO:0000033 alpha-1,3-mannosyltransferase activity(GO:0000033)
0.3 1.7 GO:0000340 RNA 7-methylguanosine cap binding(GO:0000340)
0.3 16.0 GO:0070063 RNA polymerase binding(GO:0070063)
0.3 4.4 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.3 1.6 GO:0004826 phenylalanine-tRNA ligase activity(GO:0004826)
0.3 4.1 GO:0003958 NADPH-hemoprotein reductase activity(GO:0003958)
0.3 7.3 GO:0005540 hyaluronic acid binding(GO:0005540)
0.3 1.3 GO:0004668 protein-arginine deiminase activity(GO:0004668)
0.3 1.1 GO:0000900 translation repressor activity, nucleic acid binding(GO:0000900)
0.3 2.9 GO:0008409 5'-3' exonuclease activity(GO:0008409)
0.3 2.9 GO:0033170 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.3 1.5 GO:0000828 inositol hexakisphosphate kinase activity(GO:0000828) inositol hexakisphosphate 5-kinase activity(GO:0000832) inositol hexakisphosphate 1-kinase activity(GO:0052723) inositol hexakisphosphate 3-kinase activity(GO:0052724)
0.3 1.8 GO:0016428 tRNA (cytosine-5-)-methyltransferase activity(GO:0016428)
0.3 1.8 GO:0043024 ribosomal small subunit binding(GO:0043024)
0.3 2.5 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.2 6.0 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.2 3.0 GO:0016864 protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.2 0.7 GO:0032129 histone deacetylase activity (H3-K9 specific)(GO:0032129) NAD-dependent histone deacetylase activity (H3-K9 specific)(GO:0046969)
0.2 1.2 GO:0004430 1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.2 1.7 GO:0034431 endopolyphosphatase activity(GO:0000298) diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) bis(5'-adenosyl)-hexaphosphatase activity(GO:0034431) bis(5'-adenosyl)-pentaphosphatase activity(GO:0034432)
0.2 26.9 GO:0003697 single-stranded DNA binding(GO:0003697)
0.2 2.2 GO:0043208 glycosphingolipid binding(GO:0043208)
0.2 0.7 GO:0004637 phosphoribosylamine-glycine ligase activity(GO:0004637)
0.2 5.1 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.2 0.9 GO:0046976 histone methyltransferase activity (H3-K27 specific)(GO:0046976)
0.2 2.8 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
0.2 1.6 GO:0004849 uridine kinase activity(GO:0004849)
0.2 5.9 GO:0070003 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.2 3.1 GO:0001056 RNA polymerase III activity(GO:0001056)
0.2 1.5 GO:0051575 5'-deoxyribose-5-phosphate lyase activity(GO:0051575)
0.2 2.0 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.2 18.8 GO:0030507 spectrin binding(GO:0030507)
0.2 9.0 GO:0043015 gamma-tubulin binding(GO:0043015)
0.2 0.9 GO:0070976 TIR domain binding(GO:0070976)
0.2 1.3 GO:0004832 valine-tRNA ligase activity(GO:0004832)
0.2 1.5 GO:1990247 N6-methyladenosine-containing RNA binding(GO:1990247)
0.2 1.7 GO:0042731 PH domain binding(GO:0042731)
0.2 4.3 GO:0016668 oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor(GO:0016668)
0.2 0.8 GO:0008073 ornithine decarboxylase inhibitor activity(GO:0008073)
0.2 1.2 GO:0046920 alpha-(1->3)-fucosyltransferase activity(GO:0046920)
0.2 1.0 GO:0048156 tau protein binding(GO:0048156)
0.2 5.0 GO:0017160 Ral GTPase binding(GO:0017160)
0.2 0.8 GO:0035650 AP-1 adaptor complex binding(GO:0035650)
0.2 0.4 GO:0031871 proteinase activated receptor binding(GO:0031871)
0.2 6.1 GO:0017025 TBP-class protein binding(GO:0017025)
0.2 2.7 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.2 2.1 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.2 1.3 GO:0031013 troponin I binding(GO:0031013)
0.2 0.7 GO:0004052 arachidonate 12-lipoxygenase activity(GO:0004052)
0.2 0.9 GO:0051998 carboxyl-O-methyltransferase activity(GO:0010340) protein carboxyl O-methyltransferase activity(GO:0051998)
0.2 4.5 GO:0004622 lysophospholipase activity(GO:0004622)
0.2 3.8 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.2 21.1 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.2 0.7 GO:0030627 pre-mRNA 5'-splice site binding(GO:0030627)
0.2 4.8 GO:0003684 damaged DNA binding(GO:0003684)
0.2 10.5 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.2 1.6 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.2 4.9 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.2 5.7 GO:0004364 glutathione transferase activity(GO:0004364)
0.2 0.7 GO:0047710 bis(5'-adenosyl)-triphosphatase activity(GO:0047710)
0.2 1.0 GO:0035252 UDP-xylosyltransferase activity(GO:0035252)
0.2 4.0 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.2 2.6 GO:0019855 calcium channel inhibitor activity(GO:0019855)
0.2 1.3 GO:0042162 telomeric DNA binding(GO:0042162)
0.2 0.8 GO:0034602 oxoglutarate dehydrogenase (NAD+) activity(GO:0034602)
0.2 0.6 GO:0003998 acylphosphatase activity(GO:0003998)
0.2 2.1 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.2 1.1 GO:0050308 sugar-phosphatase activity(GO:0050308)
0.2 5.3 GO:0070064 proline-rich region binding(GO:0070064)
0.2 0.8 GO:0047696 beta-adrenergic receptor kinase activity(GO:0047696)
0.2 16.5 GO:0003777 microtubule motor activity(GO:0003777)
0.1 0.7 GO:0070883 pre-miRNA binding(GO:0070883)
0.1 3.4 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.1 0.6 GO:0004663 Rab geranylgeranyltransferase activity(GO:0004663)
0.1 1.2 GO:0008479 queuine tRNA-ribosyltransferase activity(GO:0008479)
0.1 1.0 GO:0008158 hedgehog receptor activity(GO:0008158)
0.1 2.0 GO:0015187 glycine transmembrane transporter activity(GO:0015187)
0.1 0.7 GO:0070728 leucine binding(GO:0070728)
0.1 6.9 GO:0005484 SNAP receptor activity(GO:0005484)
0.1 0.3 GO:0001160 transcription termination site sequence-specific DNA binding(GO:0001147) transcription termination site DNA binding(GO:0001160)
0.1 0.6 GO:0016433 rRNA (adenine) methyltransferase activity(GO:0016433)
0.1 1.0 GO:0008417 fucosyltransferase activity(GO:0008417)
0.1 7.7 GO:0042169 SH2 domain binding(GO:0042169)
0.1 0.4 GO:0061711 N(6)-L-threonylcarbamoyladenine synthase(GO:0061711)
0.1 0.6 GO:0070180 large ribosomal subunit rRNA binding(GO:0070180)
0.1 1.8 GO:0008173 RNA methyltransferase activity(GO:0008173)
0.1 4.0 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.1 1.4 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.1 1.1 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.1 0.7 GO:0031996 thioesterase binding(GO:0031996)
0.1 7.9 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.1 7.8 GO:0097472 cyclin-dependent protein kinase activity(GO:0097472)
0.1 2.5 GO:0019789 SUMO transferase activity(GO:0019789)
0.1 0.9 GO:0016861 intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.1 22.8 GO:0003735 structural constituent of ribosome(GO:0003735)
0.1 1.0 GO:0070990 snRNP binding(GO:0070990) U1 snRNP binding(GO:1990446)
0.1 1.7 GO:0048273 mitogen-activated protein kinase p38 binding(GO:0048273)
0.1 1.0 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.1 3.0 GO:0005521 lamin binding(GO:0005521)
0.1 4.8 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.1 0.7 GO:0004095 carnitine O-palmitoyltransferase activity(GO:0004095) O-palmitoyltransferase activity(GO:0016416)
0.1 1.1 GO:0008499 UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity(GO:0008499)
0.1 0.5 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.1 1.2 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.1 13.2 GO:0036459 thiol-dependent ubiquitinyl hydrolase activity(GO:0036459) ubiquitinyl hydrolase activity(GO:0101005)
0.1 3.0 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.1 1.5 GO:0004707 MAP kinase activity(GO:0004707)
0.1 4.3 GO:0008376 acetylgalactosaminyltransferase activity(GO:0008376)
0.1 5.4 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.1 0.9 GO:0090079 translation regulator activity, nucleic acid binding(GO:0090079)
0.1 0.9 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.1 2.3 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.1 2.3 GO:0017049 GTP-Rho binding(GO:0017049)
0.1 1.5 GO:0031748 D1 dopamine receptor binding(GO:0031748)
0.1 5.3 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.1 6.0 GO:0001786 phosphatidylserine binding(GO:0001786)
0.1 0.4 GO:0003681 bent DNA binding(GO:0003681)
0.1 0.3 GO:0004962 endothelin receptor activity(GO:0004962)
0.1 0.4 GO:0051731 ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity(GO:0046404) polynucleotide 5'-hydroxyl-kinase activity(GO:0051731) polydeoxyribonucleotide kinase activity(GO:0051733) ATP-dependent polynucleotide kinase activity(GO:0051734)
0.1 1.6 GO:0051959 dynein light intermediate chain binding(GO:0051959)
0.1 0.7 GO:0035033 histone deacetylase regulator activity(GO:0035033)
0.1 1.7 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.1 0.9 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.1 2.0 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.1 2.6 GO:0004623 phospholipase A2 activity(GO:0004623)
0.1 1.3 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.1 6.0 GO:0004519 endonuclease activity(GO:0004519)
0.1 5.8 GO:0004386 helicase activity(GO:0004386)
0.1 3.0 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.1 1.5 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.1 3.3 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.1 2.9 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.1 0.2 GO:0043559 insulin binding(GO:0043559)
0.1 1.9 GO:0017075 syntaxin-1 binding(GO:0017075)
0.1 1.9 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.1 0.2 GO:0016781 selenide, water dikinase activity(GO:0004756) phosphotransferase activity, paired acceptors(GO:0016781)
0.1 1.9 GO:0018024 histone-lysine N-methyltransferase activity(GO:0018024)
0.1 2.6 GO:0070566 adenylyltransferase activity(GO:0070566)
0.1 15.9 GO:0051015 actin filament binding(GO:0051015)
0.1 0.9 GO:0017162 aryl hydrocarbon receptor binding(GO:0017162)
0.1 1.6 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.1 2.0 GO:0097602 cullin family protein binding(GO:0097602)
0.1 0.9 GO:0070403 NAD+ binding(GO:0070403)
0.1 1.8 GO:0046965 retinoid X receptor binding(GO:0046965)
0.1 0.6 GO:0030306 ADP-ribosylation factor binding(GO:0030306)
0.1 1.4 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.1 0.9 GO:0030331 estrogen receptor binding(GO:0030331)
0.1 2.6 GO:0043531 ADP binding(GO:0043531)
0.1 2.3 GO:0008198 ferrous iron binding(GO:0008198)
0.1 1.0 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.1 0.1 GO:0015173 aromatic amino acid transmembrane transporter activity(GO:0015173)
0.1 114.5 GO:0003723 RNA binding(GO:0003723)
0.1 0.7 GO:0015181 arginine transmembrane transporter activity(GO:0015181)
0.1 0.7 GO:0000182 rDNA binding(GO:0000182)
0.1 2.3 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.1 1.9 GO:0008009 chemokine activity(GO:0008009)
0.1 0.6 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.1 42.1 GO:0004842 ubiquitin-protein transferase activity(GO:0004842)
0.1 3.1 GO:0019209 kinase activator activity(GO:0019209)
0.1 1.5 GO:0052866 phosphatidylinositol phosphate phosphatase activity(GO:0052866)
0.1 0.6 GO:0043560 insulin receptor substrate binding(GO:0043560)
0.1 2.1 GO:0019706 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.1 1.0 GO:0004407 histone deacetylase activity(GO:0004407) protein deacetylase activity(GO:0033558)
0.1 4.1 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.1 0.7 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.1 0.2 GO:0043008 ATP-dependent protein binding(GO:0043008)
0.1 1.6 GO:0005048 signal sequence binding(GO:0005048)
0.1 0.3 GO:0017151 DEAD/H-box RNA helicase binding(GO:0017151)
0.1 0.2 GO:0004802 transketolase activity(GO:0004802)
0.1 1.0 GO:0008484 sulfuric ester hydrolase activity(GO:0008484)
0.1 3.6 GO:0030276 clathrin binding(GO:0030276)
0.1 1.3 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.1 4.7 GO:0051082 unfolded protein binding(GO:0051082)
0.1 0.3 GO:0070568 guanylyltransferase activity(GO:0070568)
0.1 0.8 GO:0042577 lipid phosphatase activity(GO:0042577)
0.0 0.8 GO:0008307 structural constituent of muscle(GO:0008307)
0.0 0.8 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.0 5.5 GO:0005178 integrin binding(GO:0005178)
0.0 2.6 GO:0000149 SNARE binding(GO:0000149)
0.0 0.0 GO:0004741 [pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
0.0 7.3 GO:0003714 transcription corepressor activity(GO:0003714)
0.0 1.8 GO:0050699 WW domain binding(GO:0050699)
0.0 3.7 GO:0019208 phosphatase regulator activity(GO:0019208)
0.0 0.1 GO:0004645 phosphorylase activity(GO:0004645)
0.0 0.9 GO:0001618 virus receptor activity(GO:0001618)
0.0 0.3 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
0.0 0.6 GO:0004190 aspartic-type endopeptidase activity(GO:0004190)
0.0 7.2 GO:0045296 cadherin binding(GO:0045296)
0.0 0.0 GO:0031177 phosphopantetheine binding(GO:0031177)
0.0 1.0 GO:0019894 kinesin binding(GO:0019894)
0.0 1.7 GO:0008234 cysteine-type peptidase activity(GO:0008234)
0.0 1.9 GO:0033613 activating transcription factor binding(GO:0033613)
0.0 0.4 GO:0005161 platelet-derived growth factor receptor binding(GO:0005161)
0.0 0.3 GO:0004954 prostanoid receptor activity(GO:0004954)
0.0 0.4 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.0 0.3 GO:0004385 guanylate kinase activity(GO:0004385)
0.0 0.0 GO:0008169 C-methyltransferase activity(GO:0008169)
0.0 0.3 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.0 0.5 GO:0051019 mitogen-activated protein kinase binding(GO:0051019)
0.0 0.1 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
0.0 0.6 GO:0031593 polyubiquitin binding(GO:0031593)
0.0 1.0 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.0 0.1 GO:0048495 Roundabout binding(GO:0048495)
0.0 0.2 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.0 0.2 GO:0017154 semaphorin receptor activity(GO:0017154)
0.0 0.2 GO:0015035 protein disulfide oxidoreductase activity(GO:0015035)
0.0 4.6 GO:0005096 GTPase activator activity(GO:0005096)
0.0 0.5 GO:0001540 beta-amyloid binding(GO:0001540)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
7.0 7.0 PID EPHA2 FWD PATHWAY EPHA2 forward signaling
1.1 27.9 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
1.0 59.0 PID AURORA B PATHWAY Aurora B signaling
0.8 7.2 SA G1 AND S PHASES Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.8 13.4 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.6 36.3 PID PLK1 PATHWAY PLK1 signaling events
0.5 3.2 ST IL 13 PATHWAY Interleukin 13 (IL-13) Pathway
0.4 7.9 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.3 16.2 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.3 18.1 PID PI3KCI AKT PATHWAY Class I PI3K signaling events mediated by Akt
0.3 11.9 PID FOXM1 PATHWAY FOXM1 transcription factor network
0.2 8.0 PID ATM PATHWAY ATM pathway
0.2 29.9 PID AR PATHWAY Coregulation of Androgen receptor activity
0.2 17.3 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.2 12.5 PID INTEGRIN3 PATHWAY Beta3 integrin cell surface interactions
0.2 23.5 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.2 10.2 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.2 3.1 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.2 2.3 PID FAK PATHWAY Signaling events mediated by focal adhesion kinase
0.2 8.7 ST P38 MAPK PATHWAY p38 MAPK Pathway
0.2 11.4 PID P53 REGULATION PATHWAY p53 pathway
0.2 4.6 PID ARF 3PATHWAY Arf1 pathway
0.2 2.1 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.2 7.3 PID IL2 PI3K PATHWAY IL2 signaling events mediated by PI3K
0.2 6.8 PID TELOMERASE PATHWAY Regulation of Telomerase
0.1 0.7 ST TYPE I INTERFERON PATHWAY Type I Interferon (alpha/beta IFN) Pathway
0.1 8.7 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.1 12.8 PID NOTCH PATHWAY Notch signaling pathway
0.1 3.0 PID SYNDECAN 2 PATHWAY Syndecan-2-mediated signaling events
0.1 2.5 PID ATR PATHWAY ATR signaling pathway
0.1 3.2 ST TUMOR NECROSIS FACTOR PATHWAY Tumor Necrosis Factor Pathway.
0.1 4.2 PID FANCONI PATHWAY Fanconi anemia pathway
0.1 3.5 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.1 7.2 PID RB 1PATHWAY Regulation of retinoblastoma protein
0.1 3.0 ST JNK MAPK PATHWAY JNK MAPK Pathway
0.1 6.4 PID RAC1 PATHWAY RAC1 signaling pathway
0.1 5.3 PID ARF6 TRAFFICKING PATHWAY Arf6 trafficking events
0.1 4.0 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.1 7.9 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network
0.1 1.4 ST PHOSPHOINOSITIDE 3 KINASE PATHWAY PI3K Pathway
0.1 4.7 PID HEDGEHOG GLI PATHWAY Hedgehog signaling events mediated by Gli proteins
0.1 5.2 PID ILK PATHWAY Integrin-linked kinase signaling
0.1 6.0 PID CMYB PATHWAY C-MYB transcription factor network
0.1 0.8 ST INTERLEUKIN 4 PATHWAY Interleukin 4 (IL-4) Pathway
0.1 1.7 ST GA13 PATHWAY G alpha 13 Pathway
0.1 3.6 PID HDAC CLASSI PATHWAY Signaling events mediated by HDAC Class I
0.1 1.4 PID CXCR4 PATHWAY CXCR4-mediated signaling events
0.1 2.3 PID E2F PATHWAY E2F transcription factor network
0.1 2.1 PID THROMBIN PAR1 PATHWAY PAR1-mediated thrombin signaling events
0.0 2.1 PID IL4 2PATHWAY IL4-mediated signaling events
0.0 0.3 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 1.0 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.0 2.1 PID P75 NTR PATHWAY p75(NTR)-mediated signaling
0.0 0.7 PID CD40 PATHWAY CD40/CD40L signaling
0.0 1.3 PID AP1 PATHWAY AP-1 transcription factor network
0.0 0.8 PID TCPTP PATHWAY Signaling events mediated by TCPTP
0.0 0.8 ST FAS SIGNALING PATHWAY Fas Signaling Pathway
0.0 0.6 NABA COLLAGENS Genes encoding collagen proteins
0.0 1.2 PID TRKR PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.0 2.1 PID P73PATHWAY p73 transcription factor network
0.0 0.3 PID BARD1 PATHWAY BARD1 signaling events
0.0 1.5 PID SMAD2 3NUCLEAR PATHWAY Regulation of nuclear SMAD2/3 signaling
0.0 1.2 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.0 1.3 PID ERBB1 INTERNALIZATION PATHWAY Internalization of ErbB1
0.0 0.5 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.0 1.3 PID REG GR PATHWAY Glucocorticoid receptor regulatory network
0.0 0.2 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.0 0.6 PID ECADHERIN NASCENT AJ PATHWAY E-cadherin signaling in the nascent adherens junction
0.0 1.3 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.0 0.6 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.0 0.7 PID AVB3 INTEGRIN PATHWAY Integrins in angiogenesis
0.0 0.0 PID INTEGRIN CS PATHWAY Integrin family cell surface interactions
0.0 0.3 PID CDC42 PATHWAY CDC42 signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
2.2 2.2 REACTOME P53 DEPENDENT G1 DNA DAMAGE RESPONSE Genes involved in p53-Dependent G1 DNA Damage Response
1.4 31.0 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
1.3 5.4 REACTOME BINDING AND ENTRY OF HIV VIRION Genes involved in Binding and entry of HIV virion
1.3 19.4 REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1 Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
1.2 27.3 REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
1.2 9.7 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
1.2 21.8 REACTOME G1 S SPECIFIC TRANSCRIPTION Genes involved in G1/S-Specific Transcription
1.2 6.0 REACTOME SCFSKP2 MEDIATED DEGRADATION OF P27 P21 Genes involved in SCF(Skp2)-mediated degradation of p27/p21
1.1 13.7 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
1.1 11.4 REACTOME E2F MEDIATED REGULATION OF DNA REPLICATION Genes involved in E2F mediated regulation of DNA replication
1.0 10.4 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
1.0 38.8 REACTOME TRANSPORT OF RIBONUCLEOPROTEINS INTO THE HOST NUCLEUS Genes involved in Transport of Ribonucleoproteins into the Host Nucleus
0.9 17.4 REACTOME VIRAL MESSENGER RNA SYNTHESIS Genes involved in Viral Messenger RNA Synthesis
0.9 15.3 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1
0.8 9.7 REACTOME TRANSPORT OF MATURE MRNA DERIVED FROM AN INTRONLESS TRANSCRIPT Genes involved in Transport of Mature mRNA Derived from an Intronless Transcript
0.8 7.2 REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC Genes involved in Regulation of ornithine decarboxylase (ODC)
0.8 23.5 REACTOME TRANSPORT OF MATURE TRANSCRIPT TO CYTOPLASM Genes involved in Transport of Mature Transcript to Cytoplasm
0.7 48.7 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.7 10.2 REACTOME ACTIVATION OF THE MRNA UPON BINDING OF THE CAP BINDING COMPLEX AND EIFS AND SUBSEQUENT BINDING TO 43S Genes involved in Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S
0.7 17.7 REACTOME INHIBITION OF THE PROTEOLYTIC ACTIVITY OF APC C REQUIRED FOR THE ONSET OF ANAPHASE BY MITOTIC SPINDLE CHECKPOINT COMPONENTS Genes involved in Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components
0.7 14.0 REACTOME ACTIVATION OF THE PRE REPLICATIVE COMPLEX Genes involved in Activation of the pre-replicative complex
0.7 6.3 REACTOME MICRORNA MIRNA BIOGENESIS Genes involved in MicroRNA (miRNA) Biogenesis
0.6 29.1 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.6 6.4 REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.6 6.8 REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.6 2.8 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.5 2.7 REACTOME ASSOCIATION OF LICENSING FACTORS WITH THE PRE REPLICATIVE COMPLEX Genes involved in Association of licensing factors with the pre-replicative complex
0.5 44.6 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.5 4.6 REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
0.5 4.4 REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.5 6.5 REACTOME RESOLUTION OF AP SITES VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY Genes involved in Resolution of AP sites via the single-nucleotide replacement pathway
0.5 51.6 REACTOME MRNA SPLICING Genes involved in mRNA Splicing
0.4 6.7 REACTOME EXTENSION OF TELOMERES Genes involved in Extension of Telomeres
0.4 2.5 REACTOME HYALURONAN METABOLISM Genes involved in Hyaluronan metabolism
0.4 5.3 REACTOME SPRY REGULATION OF FGF SIGNALING Genes involved in Spry regulation of FGF signaling
0.4 12.9 REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.4 8.3 REACTOME RNA POL III TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase III Transcription Termination
0.4 8.7 REACTOME ACYL CHAIN REMODELLING OF PG Genes involved in Acyl chain remodelling of PG
0.4 24.6 REACTOME 3 UTR MEDIATED TRANSLATIONAL REGULATION Genes involved in 3' -UTR-mediated translational regulation
0.3 8.2 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.3 3.0 REACTOME DESTABILIZATION OF MRNA BY BRF1 Genes involved in Destabilization of mRNA by Butyrate Response Factor 1 (BRF1)
0.3 5.3 REACTOME REGULATION OF IFNG SIGNALING Genes involved in Regulation of IFNG signaling
0.3 6.9 REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC Genes involved in Formation of tubulin folding intermediates by CCT/TriC
0.3 4.9 REACTOME METABOLISM OF NON CODING RNA Genes involved in Metabolism of non-coding RNA
0.3 7.4 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.3 1.8 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.3 9.7 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.3 4.0 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.3 7.0 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.3 19.1 REACTOME REGULATION OF MITOTIC CELL CYCLE Genes involved in Regulation of mitotic cell cycle
0.3 6.8 REACTOME PYRUVATE METABOLISM Genes involved in Pyruvate metabolism
0.3 4.4 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.3 2.3 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.2 18.1 REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.2 10.6 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.2 1.5 REACTOME ERKS ARE INACTIVATED Genes involved in ERKs are inactivated
0.2 5.1 REACTOME SEMA3A PAK DEPENDENT AXON REPULSION Genes involved in Sema3A PAK dependent Axon repulsion
0.2 5.5 REACTOME KINESINS Genes involved in Kinesins
0.2 0.8 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.2 14.2 REACTOME DNA REPAIR Genes involved in DNA Repair
0.2 1.3 REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 2 PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 2 Promoter
0.2 5.3 REACTOME LATE PHASE OF HIV LIFE CYCLE Genes involved in Late Phase of HIV Life Cycle
0.2 6.8 REACTOME NOD1 2 SIGNALING PATHWAY Genes involved in NOD1/2 Signaling Pathway
0.2 4.1 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.2 5.2 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.2 5.4 REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
0.2 9.7 REACTOME TRANSLATION Genes involved in Translation
0.2 2.7 REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
0.2 2.5 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.2 6.0 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.2 3.2 REACTOME REGULATION OF SIGNALING BY CBL Genes involved in Regulation of signaling by CBL
0.2 2.1 REACTOME NONSENSE MEDIATED DECAY ENHANCED BY THE EXON JUNCTION COMPLEX Genes involved in Nonsense Mediated Decay Enhanced by the Exon Junction Complex
0.1 3.3 REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS Genes involved in Trafficking of GluR2-containing AMPA receptors
0.1 1.9 REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY Genes involved in TRAF3-dependent IRF activation pathway
0.1 4.6 REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.1 0.9 REACTOME P75NTR RECRUITS SIGNALLING COMPLEXES Genes involved in p75NTR recruits signalling complexes
0.1 0.2 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.1 2.6 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.1 0.8 REACTOME OLFACTORY SIGNALING PATHWAY Genes involved in Olfactory Signaling Pathway
0.1 2.5 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.1 1.2 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.1 1.0 REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS Genes involved in Thrombin signalling through proteinase activated receptors (PARs)
0.1 0.8 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.1 2.9 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.1 0.4 REACTOME DESTABILIZATION OF MRNA BY KSRP Genes involved in Destabilization of mRNA by KSRP
0.1 1.6 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.1 1.9 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.1 1.4 REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.1 0.7 REACTOME REGULATION OF IFNA SIGNALING Genes involved in Regulation of IFNA signaling
0.1 3.0 REACTOME INSULIN RECEPTOR RECYCLING Genes involved in Insulin receptor recycling
0.1 1.2 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.1 2.2 REACTOME TRNA AMINOACYLATION Genes involved in tRNA Aminoacylation
0.1 2.0 REACTOME RNA POL I TRANSCRIPTION Genes involved in RNA Polymerase I Transcription
0.1 18.0 REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.1 1.3 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.1 2.1 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.1 0.7 REACTOME ACYL CHAIN REMODELLING OF PC Genes involved in Acyl chain remodelling of PC
0.1 8.3 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.1 0.7 REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane
0.1 2.6 REACTOME THROMBOXANE SIGNALLING THROUGH TP RECEPTOR Genes involved in Thromboxane signalling through TP receptor
0.1 0.7 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.1 0.9 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.1 0.8 REACTOME PREFOLDIN MEDIATED TRANSFER OF SUBSTRATE TO CCT TRIC Genes involved in Prefoldin mediated transfer of substrate to CCT/TriC
0.1 1.4 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.1 0.4 REACTOME DOWNSTREAM SIGNAL TRANSDUCTION Genes involved in Downstream signal transduction
0.1 0.2 REACTOME IRAK1 RECRUITS IKK COMPLEX Genes involved in IRAK1 recruits IKK complex
0.1 0.4 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.1 1.8 REACTOME PYRIMIDINE METABOLISM Genes involved in Pyrimidine metabolism
0.1 0.5 REACTOME RETROGRADE NEUROTROPHIN SIGNALLING Genes involved in Retrograde neurotrophin signalling
0.0 1.3 REACTOME N GLYCAN ANTENNAE ELONGATION IN THE MEDIAL TRANS GOLGI Genes involved in N-glycan antennae elongation in the medial/trans-Golgi
0.0 1.1 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0 0.7 REACTOME ENOS ACTIVATION AND REGULATION Genes involved in eNOS activation and regulation
0.0 0.8 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.0 0.2 REACTOME DESTABILIZATION OF MRNA BY AUF1 HNRNP D0 Genes involved in Destabilization of mRNA by AUF1 (hnRNP D0)
0.0 2.3 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.0 0.7 REACTOME REGULATION OF AMPK ACTIVITY VIA LKB1 Genes involved in Regulation of AMPK activity via LKB1
0.0 1.1 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.0 1.0 REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
0.0 0.4 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
0.0 1.1 REACTOME INTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Intrinsic Pathway for Apoptosis
0.0 0.4 REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.0 1.3 REACTOME G ALPHA Z SIGNALLING EVENTS Genes involved in G alpha (z) signalling events
0.0 0.5 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0 0.4 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.0 2.4 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.0 1.0 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 0.2 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0 1.3 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.0 1.9 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.0 0.1 REACTOME OPSINS Genes involved in Opsins
0.0 0.2 REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
0.0 0.1 REACTOME CTNNB1 PHOSPHORYLATION CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.0 0.3 REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.0 0.3 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.0 0.1 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.0 0.4 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.0 0.1 REACTOME RECRUITMENT OF MITOTIC CENTROSOME PROTEINS AND COMPLEXES Genes involved in Recruitment of mitotic centrosome proteins and complexes