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GSE58827: Dynamics of the Mouse Liver

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Results for Pax1_Pax9

Z-value: 0.29

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Transcription factors associated with Pax1_Pax9

Gene Symbol Gene ID Gene Info
ENSMUSG00000037034.17 paired box 1
ENSMUSG00000001497.19 paired box 9

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Pax9mm39_v1_chr12_+_56742413_567424590.372.5e-02Click!
Pax1mm39_v1_chr2_+_147203845_147203886-0.153.8e-01Click!

Activity profile of Pax1_Pax9 motif

Sorted Z-values of Pax1_Pax9 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr10_+_75409282 1.98 ENSMUST00000006508.10
gamma-glutamyltransferase 1
chr2_+_84564394 1.88 ENSMUST00000238573.2
ENSMUST00000090729.9
yippee like 4
chr9_-_22300409 1.34 ENSMUST00000040912.9
anillin, actin binding protein
chr9_+_96078299 1.12 ENSMUST00000165120.9
transcription factor Dp 2
chr5_-_129864202 0.80 ENSMUST00000136507.4
phosphoserine phosphatase
chr4_+_114857348 0.58 ENSMUST00000030490.13
Scl/Tal1 interrupting locus
chr17_-_24424456 0.50 ENSMUST00000201583.2
ENSMUST00000202925.4
ENSMUST00000167791.9
ENSMUST00000201960.4
ENSMUST00000040474.11
ENSMUST00000201089.4
ENSMUST00000201301.4
ENSMUST00000201805.4
ENSMUST00000168410.9
ENSMUST00000097376.10
TBC1 domain family, member 24
chr7_-_23998735 0.49 ENSMUST00000145131.8
zinc finger protein 61
chr4_-_117232650 0.42 ENSMUST00000094853.9
ring finger protein 220
chr9_+_21249118 0.38 ENSMUST00000034697.8
solute carrier family 44, member 2
chr14_+_32938774 0.38 ENSMUST00000111956.9
Rho GTPase activating protein 22
chr5_+_112403678 0.36 ENSMUST00000031286.13
ENSMUST00000131673.8
ENSMUST00000112375.2
crystallin, beta B1
chr5_+_129864044 0.34 ENSMUST00000201414.5
chaperonin containing Tcp1, subunit 6a (zeta)
chr17_-_75858835 0.32 ENSMUST00000234785.2
ENSMUST00000112507.4
family with sequence similarity 98, member A
chr7_+_48438751 0.28 ENSMUST00000118927.8
ENSMUST00000125280.8
zinc finger, DHHC domain containing 13
chr16_+_87350202 0.27 ENSMUST00000026700.8
Map3k7 C-terminal like
chr8_+_31640332 0.24 ENSMUST00000209851.2
ENSMUST00000098842.3
ENSMUST00000210129.2
TELO2 interacting protein 2
chrX_+_73356597 0.23 ENSMUST00000114160.2
family with sequence similarity 50, member A
chr4_+_11558905 0.22 ENSMUST00000095145.12
ENSMUST00000108306.9
ENSMUST00000070755.13
RAD54 homolog B (S. cerevisiae)
chr9_-_96993169 0.20 ENSMUST00000085206.11
solute carrier family 25, member 36
chr4_+_114857370 0.16 ENSMUST00000129957.8
Scl/Tal1 interrupting locus
chr17_-_28128180 0.14 ENSMUST00000114848.8
TATA-box binding protein associated factor 11
chr2_+_177834868 0.08 ENSMUST00000103065.2
phosphatase and actin regulator 3
chr17_+_28128307 0.08 ENSMUST00000233525.2
ENSMUST00000025058.15
ENSMUST00000233866.2
ankyrin repeat and SAM domain containing 1
chr8_+_71176713 0.04 ENSMUST00000034307.14
ENSMUST00000239435.2
ENSMUST00000239487.2
ENSMUST00000110095.3
phosphodiesterase 4C, cAMP specific
chr17_+_28128250 0.03 ENSMUST00000114842.9
ENSMUST00000088027.7
ankyrin repeat and SAM domain containing 1

Network of associatons between targets according to the STRING database.

First level regulatory network of Pax1_Pax9

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.3 GO:1904172 positive regulation of bleb assembly(GO:1904172)
0.2 2.0 GO:0031179 peptide modification(GO:0031179) leukotriene D4 metabolic process(GO:1901748) leukotriene D4 biosynthetic process(GO:1901750)
0.1 0.8 GO:0006564 L-serine biosynthetic process(GO:0006564)
0.1 0.7 GO:0033504 floor plate development(GO:0033504)
0.0 0.2 GO:0072531 pyrimidine-containing compound transmembrane transport(GO:0072531)
0.0 0.5 GO:1902083 negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.0 0.3 GO:1903405 protein localization to nuclear body(GO:1903405) protein localization to Cajal body(GO:1904867) regulation of protein localization to Cajal body(GO:1904869) positive regulation of protein localization to Cajal body(GO:1904871)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.3 GO:0005826 actomyosin contractile ring(GO:0005826)
0.0 0.3 GO:0072669 tRNA-splicing ligase complex(GO:0072669)
0.0 0.3 GO:0005832 chaperonin-containing T-complex(GO:0005832)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.0 GO:0036374 glutathione hydrolase activity(GO:0036374)
0.1 0.8 GO:0004647 phosphoserine phosphatase activity(GO:0004647)
0.1 0.3 GO:0071987 WD40-repeat domain binding(GO:0071987)
0.0 0.2 GO:0015616 DNA translocase activity(GO:0015616)
0.0 0.4 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.3 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.7 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 2.0 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.0 0.8 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.0 0.3 REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC Genes involved in Formation of tubulin folding intermediates by CCT/TriC
0.0 0.4 REACTOME SYNTHESIS OF PC Genes involved in Synthesis of PC