Project

GSE58827: Dynamics of the Mouse Liver

Navigation
Downloads

Results for Pbx1_Pbx3

Z-value: 1.04

Motif logo

Transcription factors associated with Pbx1_Pbx3

Gene Symbol Gene ID Gene Info
ENSMUSG00000052534.16 pre B cell leukemia homeobox 1
ENSMUSG00000038718.16 pre B cell leukemia homeobox 3

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Pbx1mm39_v1_chr1_-_168259839_1682599160.726.4e-07Click!
Pbx3mm39_v1_chr2_-_34262012_342620560.642.3e-05Click!

Activity profile of Pbx1_Pbx3 motif

Sorted Z-values of Pbx1_Pbx3 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr19_-_9876815 7.08 ENSMUST00000237147.2
ENSMUST00000025562.9
inner centromere protein
chr7_-_142223662 5.98 ENSMUST00000228850.2
predicted gene, 49394
chr12_-_76756772 5.40 ENSMUST00000166101.2
spectrin beta, erythrocytic
chrX_-_134968985 5.35 ENSMUST00000049130.8
brain expressed X-linked 2
chrX_+_135171002 5.13 ENSMUST00000178632.8
ENSMUST00000053540.11
brain expressed X-linked 3
chrX_+_135171049 4.63 ENSMUST00000113112.2
brain expressed X-linked 3
chr19_-_9876745 4.52 ENSMUST00000237725.2
inner centromere protein
chr17_-_35304582 4.51 ENSMUST00000038507.7
lymphocyte antigen 6 complex, locus G6F
chr7_+_78563964 4.51 ENSMUST00000120331.4
interferon-stimulated protein
chr17_+_47906985 4.37 ENSMUST00000182539.8
cyclin D3
chrX_-_133709733 4.28 ENSMUST00000035559.11
armadillo repeat containing, X-linked 2
chr7_+_78563513 4.25 ENSMUST00000038142.15
interferon-stimulated protein
chr8_+_120840883 4.17 ENSMUST00000108948.8
ENSMUST00000034281.13
ENSMUST00000108951.8
RIKEN cDNA 6430548M08 gene
chr9_+_96140781 4.12 ENSMUST00000190104.7
ENSMUST00000179416.8
ENSMUST00000189606.7
transcription factor Dp 2
chr17_-_14914484 3.84 ENSMUST00000170872.3
thrombospondin 2
chr3_+_37694094 3.72 ENSMUST00000108109.8
ENSMUST00000038569.8
ENSMUST00000108107.2
sprouty RTK signaling antagonist 1
chr7_+_78564062 3.52 ENSMUST00000205981.2
interferon-stimulated protein
chr5_+_34731087 3.42 ENSMUST00000147574.8
ENSMUST00000146295.8
adducin 1 (alpha)
chr6_+_34453142 3.29 ENSMUST00000045372.6
ENSMUST00000138668.2
ENSMUST00000139067.2
2,3-bisphosphoglycerate mutase
chr4_-_43523388 3.22 ENSMUST00000107913.10
ENSMUST00000030184.12
tropomyosin 2, beta
chr5_+_34731152 3.14 ENSMUST00000001108.11
ENSMUST00000114340.9
adducin 1 (alpha)
chr5_+_34731008 3.05 ENSMUST00000114338.9
adducin 1 (alpha)
chr11_+_105975403 2.98 ENSMUST00000002044.10
mitogen-activated protein kinase kinase kinase 3
chr16_-_18880821 2.98 ENSMUST00000200568.2
immunoglobulin lambda constant 1
chrX_-_72974357 2.86 ENSMUST00000155597.2
ENSMUST00000114379.8
renin binding protein
chr18_-_67743854 2.77 ENSMUST00000115050.10
spire type actin nucleation factor 1
chr13_+_91609169 2.77 ENSMUST00000004094.15
ENSMUST00000042122.15
single-stranded DNA binding protein 2
chr7_+_19024994 2.71 ENSMUST00000108468.5
reticulon 2 (Z-band associated protein)
chr14_+_99283807 2.70 ENSMUST00000022656.8
bora, aurora kinase A activator
chr7_+_121758646 2.69 ENSMUST00000033154.8
ENSMUST00000205901.2
polo like kinase 1
chr4_-_43523595 2.66 ENSMUST00000107914.10
tropomyosin 2, beta
chr13_-_59917569 2.63 ENSMUST00000057115.7
iron-sulfur cluster assembly 1
chr11_-_5753693 2.58 ENSMUST00000020768.4
phosphoglycerate mutase 2
chr8_-_86091946 2.56 ENSMUST00000034133.14
myosin light chain kinase 3
chrX_-_72974440 2.55 ENSMUST00000116578.8
renin binding protein
chr7_+_100145192 2.48 ENSMUST00000133044.3
uncoupling protein 2 (mitochondrial, proton carrier)
chr4_+_126915104 2.48 ENSMUST00000030623.8
splicing factor proline/glutamine rich (polypyrimidine tract binding protein associated)
chr7_-_12743720 2.47 ENSMUST00000210282.2
ENSMUST00000172240.2
ENSMUST00000051390.9
ENSMUST00000209997.2
zinc finger and BTB domain containing 45
chr18_+_82493237 2.38 ENSMUST00000091789.11
ENSMUST00000114676.8
myelin basic protein
chr11_-_100331754 2.37 ENSMUST00000107397.2
ENSMUST00000092689.9
5'-nucleotidase, cytosolic IIIB
chr8_-_86091970 2.33 ENSMUST00000121972.8
myosin light chain kinase 3
chr7_-_45175570 2.32 ENSMUST00000167273.2
ENSMUST00000042105.11
protein phosphatase 1, regulatory subunit 15A
chr11_-_100331884 2.30 ENSMUST00000107399.9
ENSMUST00000092688.12
5'-nucleotidase, cytosolic IIIB
chr4_-_43523745 2.22 ENSMUST00000150592.2
tropomyosin 2, beta
chr1_-_75482975 2.19 ENSMUST00000113567.10
ENSMUST00000113565.3
obscurin-like 1
chr9_-_63619251 2.19 ENSMUST00000154323.8
SMAD family member 3
chr5_-_138170644 2.14 ENSMUST00000000505.16
minichromosome maintenance complex component 7
chr11_-_86999481 2.07 ENSMUST00000051395.9
proline rich 11
chr2_+_27776428 2.07 ENSMUST00000028280.14
collagen, type V, alpha 1
chr11_-_70120503 2.00 ENSMUST00000153449.2
ENSMUST00000000326.12
B cell CLL/lymphoma 6, member B
chr9_+_106158549 2.00 ENSMUST00000191434.2
POC1 centriolar protein A
chr6_+_135339543 1.99 ENSMUST00000205156.3
epithelial membrane protein 1
chr10_-_111833138 1.99 ENSMUST00000074805.12
GLI pathogenesis-related 1 (glioma)
chr5_-_138170077 1.90 ENSMUST00000155902.8
ENSMUST00000148879.8
minichromosome maintenance complex component 7
chr9_+_107879700 1.86 ENSMUST00000035214.11
ENSMUST00000176854.7
ENSMUST00000175874.2
inositol hexaphosphate kinase 1
chr9_+_106158212 1.84 ENSMUST00000072206.14
POC1 centriolar protein A
chr16_+_32427789 1.83 ENSMUST00000120680.2
transferrin receptor
chr13_+_91609264 1.83 ENSMUST00000231481.2
single-stranded DNA binding protein 2
chr17_-_57137898 1.78 ENSMUST00000233000.2
ENSMUST00000002444.15
ENSMUST00000086801.7
regulatory factor X, 2 (influences HLA class II expression)
chr7_-_141649003 1.74 ENSMUST00000039926.10
dual specificity phosphatase 8
chr11_-_100332619 1.71 ENSMUST00000107398.8
5'-nucleotidase, cytosolic IIIB
chr9_+_96140750 1.70 ENSMUST00000186609.7
transcription factor Dp 2
chr6_-_49191891 1.70 ENSMUST00000031838.9
insulin-like growth factor 2 mRNA binding protein 3
chr1_-_182929025 1.65 ENSMUST00000171366.7
dispatched RND transporter family member 1
chr1_-_71692320 1.61 ENSMUST00000186940.7
ENSMUST00000188894.7
ENSMUST00000188674.7
ENSMUST00000189821.7
ENSMUST00000187938.7
ENSMUST00000190780.7
ENSMUST00000186736.2
ENSMUST00000055226.13
ENSMUST00000186129.7
fibronectin 1
chr5_+_115149170 1.61 ENSMUST00000031530.9
signal peptide peptidase 3
chr3_+_88486908 1.57 ENSMUST00000195014.6
signal sequence receptor, beta
chr5_-_120726721 1.55 ENSMUST00000046426.10
two pore channel 1
chr10_-_77845571 1.50 ENSMUST00000020522.9
phosphofructokinase, liver, B-type
chr17_-_25155868 1.48 ENSMUST00000115228.9
ENSMUST00000117509.8
ENSMUST00000121723.8
ENSMUST00000119115.8
ENSMUST00000121787.8
ENSMUST00000088345.12
ENSMUST00000120035.8
ENSMUST00000115229.10
ENSMUST00000178969.8
mitogen-activated protein kinase 8 interacting protein 3
chr9_+_62754252 1.46 ENSMUST00000124984.2
ceroid-lipofuscinosis, neuronal 6
chr3_+_88486921 1.46 ENSMUST00000193934.6
ENSMUST00000192495.6
ENSMUST00000035785.9
signal sequence receptor, beta
chr4_+_140714184 1.45 ENSMUST00000168047.8
ENSMUST00000037055.14
ENSMUST00000127833.3
ATPase type 13A2
chr3_-_107145968 1.45 ENSMUST00000197758.5
prokineticin 1
chr7_+_4743114 1.41 ENSMUST00000098853.9
ENSMUST00000130215.8
ENSMUST00000108582.10
ENSMUST00000108583.9
lysine methyltransferase 5C
chr2_-_165168355 1.39 ENSMUST00000074046.13
ENSMUST00000094329.11
ENSMUST00000103088.10
ENSMUST00000128690.2
engulfment and cell motility 2
chr2_+_32253204 1.36 ENSMUST00000048964.14
ENSMUST00000113332.8
CDKN1A interacting zinc finger protein 1
chr8_+_23901506 1.36 ENSMUST00000033952.8
secreted frizzled-related protein 1
chr11_-_79971750 1.35 ENSMUST00000103233.10
ENSMUST00000061283.15
cytokine receptor-like factor 3
chr13_+_44884200 1.35 ENSMUST00000173704.8
ENSMUST00000044608.14
ENSMUST00000173367.8
jumonji, AT rich interactive domain 2
chr9_-_116004386 1.34 ENSMUST00000035014.8
transforming growth factor, beta receptor II
chr5_+_24791719 1.32 ENSMUST00000088295.9
ENSMUST00000121863.5
chondroitin polymerizing factor 2
chr2_-_121101822 1.32 ENSMUST00000110647.8
ENSMUST00000110648.8
transformation related protein 53 binding protein 1
chr1_+_57813759 1.31 ENSMUST00000167971.8
ENSMUST00000170139.8
ENSMUST00000171699.8
ENSMUST00000164302.8
spermatogenesis associated, serine-rich 2-like
chr7_+_45084257 1.29 ENSMUST00000003964.17
glycogen synthase 1, muscle
chr9_-_122123427 1.28 ENSMUST00000216670.2
anoctamin 10
chr2_+_32253692 1.27 ENSMUST00000113331.8
ENSMUST00000113338.9
CDKN1A interacting zinc finger protein 1
chr11_-_18968955 1.23 ENSMUST00000068264.14
ENSMUST00000185131.8
Meis homeobox 1
chr2_-_126460575 1.21 ENSMUST00000028838.5
histidine decarboxylase
chr15_-_79626719 1.19 ENSMUST00000089311.11
ENSMUST00000046259.14
Sad1 and UNC84 domain containing 2
chrX_-_100266032 1.19 ENSMUST00000120389.8
ENSMUST00000156473.8
ENSMUST00000077876.4
sorting nexin 12
chr15_-_81074921 1.18 ENSMUST00000131235.9
ENSMUST00000134469.9
ENSMUST00000239114.2
ENSMUST00000149582.8
myocardin related transcription factor A
chr4_-_151142351 1.16 ENSMUST00000030797.4
vesicle-associated membrane protein 3
chr6_+_142332941 1.16 ENSMUST00000032372.7
golgi transport 1B
chr17_-_50401305 1.16 ENSMUST00000113195.8
raftlin lipid raft linker 1
chr10_+_41685931 1.16 ENSMUST00000099931.11
sestrin 1
chr15_-_79626694 1.16 ENSMUST00000100439.10
Sad1 and UNC84 domain containing 2
chr16_+_94370869 1.12 ENSMUST00000119878.8
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1a
chr9_-_49710190 1.12 ENSMUST00000114476.8
ENSMUST00000193547.6
neural cell adhesion molecule 1
chr2_+_32253016 1.09 ENSMUST00000132028.8
ENSMUST00000136079.8
CDKN1A interacting zinc finger protein 1
chr2_+_158636727 1.09 ENSMUST00000029186.14
ENSMUST00000109478.9
ENSMUST00000156893.2
DEAH (Asp-Glu-Ala-His) box polypeptide 35
chr9_-_45896110 1.08 ENSMUST00000215060.2
ENSMUST00000213853.2
ENSMUST00000216334.2
platelet-activating factor acetylhydrolase, isoform 1b, subunit 2
chr2_-_113883285 1.07 ENSMUST00000090269.7
actin, alpha, cardiac muscle 1
chr9_-_122123409 1.05 ENSMUST00000214409.2
anoctamin 10
chr16_+_17051423 1.05 ENSMUST00000090190.14
ENSMUST00000232082.2
ENSMUST00000232426.2
hypermethylated in cancer 2
predicted gene, 49573
chr10_-_40178182 1.05 ENSMUST00000099945.6
ENSMUST00000238953.2
ENSMUST00000238969.2
S-adenosylmethionine decarboxylase 1
chr11_+_105927698 1.03 ENSMUST00000058438.9
DDB1 and CUL4 associated factor 7
chr11_+_87000032 1.03 ENSMUST00000020794.6
spindle and kinetochore associated complex subunit 2
chr4_-_43045685 1.02 ENSMUST00000107956.8
ENSMUST00000107957.8
family with sequence similarity 214, member B
chr3_-_8732316 1.00 ENSMUST00000042412.5
hairy/enhancer-of-split related with YRPW motif 1
chr14_-_30928737 0.97 ENSMUST00000022469.13
ENSMUST00000172142.8
nischarin
chr16_-_31019967 0.97 ENSMUST00000230614.2
ENSMUST00000058033.9
ArfGAP with coiled-coil, ankyrin repeat and PH domains 2
chr17_+_57665691 0.94 ENSMUST00000086763.13
ENSMUST00000233376.2
ENSMUST00000233840.2
ENSMUST00000232808.2
ENSMUST00000004850.8
adhesion G protein-coupled receptor E1
chr7_+_45084300 0.94 ENSMUST00000211150.2
glycogen synthase 1, muscle
chr7_-_45084012 0.94 ENSMUST00000107771.12
ENSMUST00000211666.2
RuvB-like protein 2
chr8_+_106627053 0.93 ENSMUST00000049699.9
protein serine kinase H1
chr3_+_96508400 0.90 ENSMUST00000062058.5
Lix1-like
chr14_+_55131568 0.90 ENSMUST00000116476.9
ENSMUST00000022808.14
ENSMUST00000150975.8
poly(A) binding protein, nuclear 1
chr9_-_49710058 0.90 ENSMUST00000192584.2
ENSMUST00000166811.9
neural cell adhesion molecule 1
chr9_-_95727267 0.90 ENSMUST00000093800.9
plastin 1 (I-isoform)
chr8_-_116434517 0.90 ENSMUST00000109104.2
avian musculoaponeurotic fibrosarcoma oncogene homolog
chr9_-_56151334 0.90 ENSMUST00000188142.7
pseudopodium-enriched atypical kinase 1
chr4_-_43046196 0.89 ENSMUST00000036462.12
family with sequence similarity 214, member B
chr11_+_121128042 0.87 ENSMUST00000103015.4
nuclear prelamin A recognition factor
chr5_+_103573367 0.87 ENSMUST00000048957.11
protein tyrosine phosphatase, non-receptor type 13
chr5_+_137627431 0.87 ENSMUST00000176667.8
leucine-rich repeats and calponin homology (CH) domain containing 4
chr2_-_152673585 0.87 ENSMUST00000156688.2
ENSMUST00000007803.12
BCL2-like 1
chr15_+_99600475 0.87 ENSMUST00000228984.2
ENSMUST00000229845.2
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1
chr7_-_45083688 0.87 ENSMUST00000210439.2
RuvB-like protein 2
chr14_-_61275340 0.86 ENSMUST00000225730.2
ENSMUST00000111236.4
tumor necrosis factor receptor superfamily, member 19
chr19_+_55882942 0.83 ENSMUST00000142291.8
transcription factor 7 like 2, T cell specific, HMG box
chr11_+_55360502 0.83 ENSMUST00000018727.4
GTPase activating protein (SH3 domain) binding protein 1
chr10_-_80269436 0.82 ENSMUST00000105346.10
ENSMUST00000020377.13
ENSMUST00000105340.8
ENSMUST00000020379.13
ENSMUST00000105344.8
ENSMUST00000105342.8
ENSMUST00000105345.10
ENSMUST00000105343.8
transcription factor 3
chr11_+_23206001 0.81 ENSMUST00000020538.13
ENSMUST00000109551.8
ENSMUST00000102870.8
ENSMUST00000102869.8
exportin 1
chr17_-_28705055 0.79 ENSMUST00000233870.2
FK506 binding protein 5
chr7_-_126062272 0.79 ENSMUST00000032974.13
ATPase, Ca++ transporting, cardiac muscle, fast twitch 1
chr11_+_120123727 0.79 ENSMUST00000122148.8
ENSMUST00000044985.14
BAH domain and coiled-coil containing 1
chr17_+_35354430 0.79 ENSMUST00000173535.8
ENSMUST00000173952.8
BCL2-associated athanogene 6
chr3_-_27764522 0.76 ENSMUST00000195008.6
fibronectin type III domain containing 3B
chr16_-_22255264 0.75 ENSMUST00000168774.8
ets variant 5
chr2_+_29509704 0.75 ENSMUST00000095087.11
ENSMUST00000091146.12
ENSMUST00000102872.11
ENSMUST00000147755.10
Rap guanine nucleotide exchange factor (GEF) 1
chr1_-_156501860 0.75 ENSMUST00000188964.7
ENSMUST00000190607.2
ENSMUST00000079625.11
torsin family 3, member A
chr5_+_34919078 0.74 ENSMUST00000080036.3
huntingtin
chr15_+_95698574 0.74 ENSMUST00000226793.2
anoctamin 6
chr17_+_34823236 0.72 ENSMUST00000174041.8
1-acylglycerol-3-phosphate O-acyltransferase 1 (lysophosphatidic acid acyltransferase, alpha)
chr5_+_24791796 0.71 ENSMUST00000197318.2
chondroitin polymerizing factor 2
chr11_-_115704447 0.70 ENSMUST00000041684.11
ENSMUST00000156812.2
CASK-interacting protein 2
chr9_-_62895197 0.69 ENSMUST00000216209.2
protein inhibitor of activated STAT 1
chr7_+_45354512 0.69 ENSMUST00000080885.12
ENSMUST00000211513.2
ENSMUST00000211357.2
D site albumin promoter binding protein
chr2_+_109848151 0.69 ENSMUST00000028580.12
coiled-coil domain containing 34
chr13_-_107073415 0.68 ENSMUST00000080856.14
importin 11
chr5_+_139197689 0.68 ENSMUST00000148772.8
ENSMUST00000110882.8
Sad1 and UNC84 domain containing 1
chr10_+_77814358 0.68 ENSMUST00000105397.10
ENSMUST00000105398.2
cilia and flagella associated protein 410
chr3_-_27764571 0.67 ENSMUST00000046157.10
fibronectin type III domain containing 3B
chr14_-_30928623 0.66 ENSMUST00000165981.8
ENSMUST00000171735.2
nischarin
chr11_-_106889291 0.65 ENSMUST00000124541.8
karyopherin (importin) alpha 2
chr7_-_112946481 0.64 ENSMUST00000117577.8
BTB (POZ) domain containing 10
chr19_-_41969558 0.63 ENSMUST00000026168.9
ENSMUST00000171561.8
MMS19 cytosolic iron-sulfur assembly component
chr15_+_99600149 0.63 ENSMUST00000229236.2
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1
chr11_+_68582731 0.63 ENSMUST00000102611.10
myosin, heavy polypeptide 10, non-muscle
chr14_-_8122634 0.63 ENSMUST00000223589.2
interleukin 3 receptor, alpha chain
chr18_+_36780913 0.60 ENSMUST00000140061.8
multiple ankyrin repeats single KH domain binding protein 3
chr7_+_101619327 0.60 ENSMUST00000210475.2
nuclear mitotic apparatus protein 1
chr2_-_164876690 0.58 ENSMUST00000122070.2
ENSMUST00000121377.8
ENSMUST00000153905.2
ENSMUST00000040381.15
nuclear receptor coactivator 5
chr17_-_36291087 0.57 ENSMUST00000055454.14
proline-rich polypeptide 3
chr7_+_121888520 0.57 ENSMUST00000064989.12
ENSMUST00000064921.5
protein kinase C, beta
chr12_-_103304573 0.57 ENSMUST00000149431.2
ankyrin repeat and SOCS box-containing 2
chr10_+_128247598 0.57 ENSMUST00000096386.13
ring finger protein 41
chr6_+_108637816 0.57 ENSMUST00000163617.2
basic helix-loop-helix family, member e40
chr2_-_76812799 0.57 ENSMUST00000011934.13
ENSMUST00000099981.10
ENSMUST00000099980.10
ENSMUST00000111882.9
ENSMUST00000140091.8
titin
chr4_-_56802266 0.56 ENSMUST00000030140.3
elongator complex protein 1
chr2_-_35994072 0.56 ENSMUST00000112961.10
ENSMUST00000112966.10
LIM homeobox protein 6
chr10_-_116385007 0.56 ENSMUST00000164088.8
CCR4-NOT transcription complex, subunit 2
chr10_+_128247492 0.55 ENSMUST00000171342.3
ring finger protein 41
chr11_+_68582923 0.55 ENSMUST00000018887.15
myosin, heavy polypeptide 10, non-muscle
chr2_-_152673032 0.55 ENSMUST00000128172.3
BCL2-like 1
chr17_-_71160477 0.54 ENSMUST00000118283.8
TGFB-induced factor homeobox 1
chr9_+_122780111 0.54 ENSMUST00000040717.7
ENSMUST00000214652.2
ENSMUST00000217401.2
kinesin family member 15
chr9_+_21336198 0.53 ENSMUST00000165766.9
ENSMUST00000173397.8
ENSMUST00000072362.14
ENSMUST00000091087.13
ENSMUST00000115404.11
dynamin 2
chr9_-_21671571 0.52 ENSMUST00000217382.2
ENSMUST00000214149.2
ENSMUST00000098942.6
ENSMUST00000216057.2
SPC24, NDC80 kinetochore complex component, homolog (S. cerevisiae)
chr19_-_4213347 0.52 ENSMUST00000025749.15
ribosomal protein S6 kinase, polypeptide 2
chr1_+_85538554 0.52 ENSMUST00000162925.2
Sp140 nuclear body protein
chr11_+_70453806 0.51 ENSMUST00000079244.12
ENSMUST00000102558.11
misshapen-like kinase 1 (zebrafish)
chr4_-_141265745 0.51 ENSMUST00000078886.10
spen family transcription repressor
chr11_-_51497665 0.51 ENSMUST00000074669.10
ENSMUST00000101249.9
ENSMUST00000109103.4
heterogeneous nuclear ribonucleoprotein A/B
chr9_+_113760002 0.51 ENSMUST00000084885.12
ENSMUST00000009885.14
upstream binding protein 1
chr10_+_79613083 0.51 ENSMUST00000020575.5
follistatin-like 3
chr1_+_57814001 0.51 ENSMUST00000167085.8
spermatogenesis associated, serine-rich 2-like
chr7_+_25380583 0.51 ENSMUST00000108403.4
B9 protein domain 2
chr4_-_151129020 0.50 ENSMUST00000103204.11
period circadian clock 3
chr9_+_21336300 0.50 ENSMUST00000172482.8
ENSMUST00000174050.8
dynamin 2
chr5_-_18054702 0.50 ENSMUST00000165232.8
CD36 molecule
chr11_+_85243970 0.49 ENSMUST00000108056.8
ENSMUST00000108061.8
ENSMUST00000108062.8
ENSMUST00000138423.8
ENSMUST00000092821.10
ENSMUST00000074875.11
breast carcinoma amplified sequence 3
chr3_+_114697710 0.49 ENSMUST00000081752.13
olfactomedin 3
chr3_+_89122477 0.49 ENSMUST00000029682.11
thrombospondin 3
chr12_-_55033130 0.49 ENSMUST00000173433.8
ENSMUST00000173803.2
bromodomain adjacent to zinc finger domain 1A
predicted gene 20403
chr19_-_4171536 0.49 ENSMUST00000025767.14
aryl-hydrocarbon receptor-interacting protein
chr15_+_99599978 0.48 ENSMUST00000023759.6
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1
chr9_-_122123475 0.48 ENSMUST00000042546.4
anoctamin 10
chr18_+_89215575 0.48 ENSMUST00000097496.4
ENSMUST00000236452.2
CD226 antigen

Network of associatons between targets according to the STRING database.

First level regulatory network of Pbx1_Pbx3

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
2.0 12.3 GO:0000738 DNA catabolic process, exonucleolytic(GO:0000738)
1.1 9.6 GO:1903142 positive regulation of endothelial cell development(GO:1901552) positive regulation of establishment of endothelial barrier(GO:1903142)
1.0 5.9 GO:0043456 regulation of pentose-phosphate shunt(GO:0043456)
0.9 3.7 GO:0032298 positive regulation of DNA-dependent DNA replication initiation(GO:0032298)
0.9 2.7 GO:0070194 synaptonemal complex disassembly(GO:0070194)
0.9 2.6 GO:0060734 regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation(GO:0060734)
0.8 4.9 GO:0002528 regulation of vascular permeability involved in acute inflammatory response(GO:0002528)
0.8 5.4 GO:0019262 N-acetylneuraminate catabolic process(GO:0019262)
0.7 2.2 GO:0051832 evasion or tolerance of host defenses by virus(GO:0019049) avoidance of host defenses(GO:0044413) evasion or tolerance of host defenses(GO:0044415) avoidance of defenses of other organism involved in symbiotic interaction(GO:0051832) evasion or tolerance of defenses of other organism involved in symbiotic interaction(GO:0051834)
0.7 2.8 GO:1904207 regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904207) positive regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904209)
0.7 2.8 GO:0070649 formin-nucleated actin cable assembly(GO:0070649)
0.7 5.5 GO:0003431 growth plate cartilage chondrocyte development(GO:0003431)
0.6 3.7 GO:0051387 negative regulation of neurotrophin TRK receptor signaling pathway(GO:0051387)
0.6 1.7 GO:0007225 patched ligand maturation(GO:0007225) signal maturation(GO:0035638)
0.5 1.6 GO:0071288 cellular response to mercury ion(GO:0071288)
0.5 2.1 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
0.5 2.0 GO:0001928 regulation of exocyst assembly(GO:0001928)
0.5 2.4 GO:0031022 nuclear migration along microfilament(GO:0031022)
0.5 1.4 GO:1904956 regulation of midbrain dopaminergic neuron differentiation(GO:1904956) regulation of planar cell polarity pathway involved in axis elongation(GO:2000040) negative regulation of planar cell polarity pathway involved in axis elongation(GO:2000041)
0.4 1.2 GO:2000642 negative regulation of early endosome to late endosome transport(GO:2000642)
0.4 1.5 GO:0018197 peptidyl-aspartic acid modification(GO:0018197)
0.4 1.4 GO:0046898 response to cycloheximide(GO:0046898)
0.3 1.0 GO:0006597 spermine biosynthetic process(GO:0006597)
0.3 1.0 GO:1903406 regulation of sodium:potassium-exchanging ATPase activity(GO:1903406)
0.3 0.7 GO:0021817 nucleokinesis involved in cell motility in cerebral cortex radial glia guided migration(GO:0021817) nuclear migration along microtubule(GO:0030473)
0.3 4.0 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.3 1.0 GO:2000820 negative regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation(GO:2000820)
0.3 1.8 GO:0071898 regulation of estrogen receptor binding(GO:0071898) negative regulation of estrogen receptor binding(GO:0071899)
0.3 0.8 GO:0051659 maintenance of mitochondrion location(GO:0051659) relaxation of skeletal muscle(GO:0090076)
0.3 1.0 GO:0070650 actin filament bundle distribution(GO:0070650)
0.2 0.7 GO:0097045 activation of blood coagulation via clotting cascade(GO:0002543) phosphatidylserine exposure on blood platelet(GO:0097045)
0.2 1.2 GO:0001692 histamine metabolic process(GO:0001692) histidine catabolic process(GO:0006548)
0.2 1.0 GO:0032888 regulation of spindle elongation(GO:0032887) regulation of mitotic spindle elongation(GO:0032888) anastral spindle assembly(GO:0055048) protein localization to spindle pole body(GO:0071988) regulation of protein localization to spindle pole body(GO:1902363) positive regulation of protein localization to spindle pole body(GO:1902365) positive regulation of mitotic spindle elongation(GO:1902846)
0.2 0.9 GO:1904247 positive regulation of polynucleotide adenylyltransferase activity(GO:1904247)
0.2 0.9 GO:1902896 terminal web assembly(GO:1902896)
0.2 1.1 GO:0030240 skeletal muscle thin filament assembly(GO:0030240)
0.2 0.6 GO:0038156 interleukin-3-mediated signaling pathway(GO:0038156)
0.2 2.5 GO:0045876 positive regulation of sister chromatid cohesion(GO:0045876)
0.2 1.6 GO:0097428 protein maturation by iron-sulfur cluster transfer(GO:0097428)
0.2 0.7 GO:1904580 regulation of intracellular mRNA localization(GO:1904580)
0.2 1.6 GO:0051533 positive regulation of NFAT protein import into nucleus(GO:0051533)
0.2 4.4 GO:0030213 hyaluronan biosynthetic process(GO:0030213)
0.2 0.9 GO:2000334 response to linoleic acid(GO:0070543) blood microparticle formation(GO:0072564) regulation of blood microparticle formation(GO:2000332) positive regulation of blood microparticle formation(GO:2000334)
0.2 2.8 GO:0071688 striated muscle myosin thick filament assembly(GO:0071688)
0.2 1.8 GO:0033572 transferrin transport(GO:0033572)
0.2 1.9 GO:0006020 inositol metabolic process(GO:0006020)
0.1 1.2 GO:0002457 T cell antigen processing and presentation(GO:0002457)
0.1 1.6 GO:2000042 negative regulation of double-strand break repair via homologous recombination(GO:2000042)
0.1 3.0 GO:0006613 cotranslational protein targeting to membrane(GO:0006613)
0.1 0.4 GO:0002380 immunoglobulin secretion involved in immune response(GO:0002380)
0.1 0.8 GO:0002326 B cell lineage commitment(GO:0002326)
0.1 1.5 GO:0006002 fructose 6-phosphate metabolic process(GO:0006002)
0.1 2.5 GO:0061179 negative regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061179)
0.1 5.4 GO:0006779 porphyrin-containing compound biosynthetic process(GO:0006779)
0.1 0.5 GO:0051344 negative regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051344)
0.1 0.5 GO:2000016 negative regulation of determination of dorsal identity(GO:2000016)
0.1 1.4 GO:0034773 histone H4-K20 trimethylation(GO:0034773)
0.1 0.4 GO:0043686 co-translational protein modification(GO:0043686)
0.1 0.3 GO:0090367 negative regulation of mRNA modification(GO:0090367)
0.1 1.1 GO:1901525 negative regulation of macromitophagy(GO:1901525)
0.1 2.0 GO:0006337 nucleosome disassembly(GO:0006337)
0.1 1.5 GO:0007042 lysosomal lumen acidification(GO:0007042)
0.1 1.4 GO:0051574 positive regulation of histone H3-K9 methylation(GO:0051574)
0.1 0.8 GO:1904378 maintenance of unfolded protein(GO:0036506) maintenance of unfolded protein involved in ERAD pathway(GO:1904378)
0.1 0.5 GO:1903377 negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903377)
0.1 0.3 GO:0006740 NADPH regeneration(GO:0006740)
0.1 2.7 GO:1900745 positive regulation of p38MAPK cascade(GO:1900745)
0.1 0.8 GO:0098728 germ-line stem cell division(GO:0042078) male germ-line stem cell asymmetric division(GO:0048133) regulation of branching involved in mammary gland duct morphogenesis(GO:0060762) germline stem cell asymmetric division(GO:0098728)
0.1 0.8 GO:0000056 ribosomal small subunit export from nucleus(GO:0000056)
0.1 1.0 GO:0060346 bone trabecula formation(GO:0060346)
0.1 0.9 GO:0010606 positive regulation of cytoplasmic mRNA processing body assembly(GO:0010606)
0.1 0.2 GO:0045448 regulation of mitotic cell cycle, embryonic(GO:0009794) mitotic cell cycle, embryonic(GO:0045448)
0.1 1.8 GO:0001675 acrosome assembly(GO:0001675)
0.1 1.4 GO:0035493 SNARE complex assembly(GO:0035493)
0.1 1.7 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.1 1.4 GO:0060510 Type II pneumocyte differentiation(GO:0060510)
0.1 1.3 GO:0045199 maintenance of epithelial cell apical/basal polarity(GO:0045199)
0.1 0.8 GO:1902746 regulation of lens fiber cell differentiation(GO:1902746)
0.1 0.6 GO:0035405 histone-threonine phosphorylation(GO:0035405)
0.1 2.0 GO:0032060 bleb assembly(GO:0032060)
0.1 8.9 GO:0008625 extrinsic apoptotic signaling pathway via death domain receptors(GO:0008625)
0.1 1.2 GO:0060044 negative regulation of cardiac muscle cell proliferation(GO:0060044)
0.1 1.2 GO:1904262 negative regulation of TORC1 signaling(GO:1904262)
0.1 11.5 GO:0000910 cytokinesis(GO:0000910)
0.1 0.7 GO:0021506 anterior neuropore closure(GO:0021506) neuropore closure(GO:0021995)
0.1 0.7 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.1 0.4 GO:0090005 negative regulation of Golgi to plasma membrane protein transport(GO:0042997) negative regulation of establishment of protein localization to plasma membrane(GO:0090005)
0.1 0.6 GO:0031163 iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
0.1 1.0 GO:0031507 heterochromatin assembly(GO:0031507)
0.1 0.7 GO:0006654 phosphatidic acid biosynthetic process(GO:0006654)
0.1 0.3 GO:0060369 positive regulation of natural killer cell cytokine production(GO:0002729) positive regulation of Fc receptor mediated stimulatory signaling pathway(GO:0060369)
0.1 1.1 GO:0043518 negative regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043518)
0.1 0.2 GO:0046882 negative regulation of follicle-stimulating hormone secretion(GO:0046882)
0.0 0.7 GO:0051152 positive regulation of smooth muscle cell differentiation(GO:0051152)
0.0 0.4 GO:2000628 regulation of miRNA metabolic process(GO:2000628)
0.0 0.8 GO:0032486 Rap protein signal transduction(GO:0032486)
0.0 0.4 GO:0051964 negative regulation of synapse assembly(GO:0051964)
0.0 0.2 GO:0072318 clathrin coat disassembly(GO:0072318)
0.0 0.4 GO:0044334 canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition(GO:0044334)
0.0 0.7 GO:0070050 neuron cellular homeostasis(GO:0070050)
0.0 0.2 GO:0008355 olfactory learning(GO:0008355)
0.0 1.9 GO:0042092 type 2 immune response(GO:0042092)
0.0 0.8 GO:0036010 protein localization to endosome(GO:0036010)
0.0 0.9 GO:0097352 autophagosome maturation(GO:0097352)
0.0 0.5 GO:0032926 negative regulation of activin receptor signaling pathway(GO:0032926)
0.0 0.6 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.0 4.1 GO:0051965 positive regulation of synapse assembly(GO:0051965)
0.0 0.8 GO:0006308 DNA catabolic process(GO:0006308)
0.0 2.7 GO:0046324 regulation of glucose import(GO:0046324)
0.0 1.7 GO:0016239 positive regulation of macroautophagy(GO:0016239)
0.0 2.2 GO:0005978 glycogen biosynthetic process(GO:0005978) glucan biosynthetic process(GO:0009250)
0.0 1.6 GO:0016601 Rac protein signal transduction(GO:0016601)
0.0 0.1 GO:1903588 negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903588)
0.0 0.1 GO:0071287 cellular response to manganese ion(GO:0071287)
0.0 0.3 GO:1900113 negative regulation of histone H3-K9 trimethylation(GO:1900113)
0.0 0.5 GO:2000114 regulation of establishment of cell polarity(GO:2000114)
0.0 0.2 GO:0035589 G-protein coupled purinergic nucleotide receptor signaling pathway(GO:0035589)
0.0 0.8 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.0 0.5 GO:0038092 nodal signaling pathway(GO:0038092)
0.0 3.5 GO:0006910 phagocytosis, recognition(GO:0006910)
0.0 0.1 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
0.0 1.5 GO:0007257 activation of JUN kinase activity(GO:0007257)
0.0 0.2 GO:0045200 establishment or maintenance of neuroblast polarity(GO:0045196) establishment of neuroblast polarity(GO:0045200)
0.0 1.0 GO:0010508 positive regulation of autophagy(GO:0010508)
0.0 0.6 GO:0060236 regulation of mitotic spindle organization(GO:0060236)
0.0 0.6 GO:0044342 type B pancreatic cell proliferation(GO:0044342)
0.0 0.3 GO:0098989 NMDA selective glutamate receptor signaling pathway(GO:0098989)
0.0 0.6 GO:0046627 negative regulation of insulin receptor signaling pathway(GO:0046627)
0.0 0.3 GO:2000811 negative regulation of anoikis(GO:2000811)
0.0 0.3 GO:0071294 cellular response to zinc ion(GO:0071294)
0.0 0.1 GO:0098912 membrane depolarization during atrial cardiac muscle cell action potential(GO:0098912)
0.0 0.1 GO:0032237 activation of store-operated calcium channel activity(GO:0032237)
0.0 2.8 GO:0006821 chloride transport(GO:0006821)
0.0 0.2 GO:1900383 regulation of synaptic plasticity by receptor localization to synapse(GO:1900383)
0.0 0.4 GO:0070536 protein K63-linked deubiquitination(GO:0070536)
0.0 0.2 GO:0034260 negative regulation of GTPase activity(GO:0034260)
0.0 0.7 GO:0060122 inner ear receptor stereocilium organization(GO:0060122)
0.0 0.3 GO:0042921 glucocorticoid receptor signaling pathway(GO:0042921)
0.0 0.5 GO:0045187 regulation of circadian sleep/wake cycle, sleep(GO:0045187)
0.0 1.1 GO:0046427 positive regulation of JAK-STAT cascade(GO:0046427) positive regulation of STAT cascade(GO:1904894)
0.0 0.4 GO:0043153 entrainment of circadian clock by photoperiod(GO:0043153)
0.0 7.3 GO:0007015 actin filament organization(GO:0007015)
0.0 0.2 GO:0018026 peptidyl-lysine monomethylation(GO:0018026)
0.0 1.7 GO:0051028 mRNA transport(GO:0051028)
0.0 0.2 GO:0060394 negative regulation of pathway-restricted SMAD protein phosphorylation(GO:0060394)
0.0 0.3 GO:0075522 IRES-dependent viral translational initiation(GO:0075522)
0.0 0.1 GO:0032534 regulation of microvillus assembly(GO:0032534)
0.0 0.5 GO:0042462 eye photoreceptor cell development(GO:0042462)
0.0 0.0 GO:0097283 keratinocyte apoptotic process(GO:0097283) regulation of keratinocyte apoptotic process(GO:1902172)
0.0 0.1 GO:1900003 regulation of serine-type endopeptidase activity(GO:1900003) negative regulation of serine-type endopeptidase activity(GO:1900004) regulation of serine-type peptidase activity(GO:1902571) negative regulation of serine-type peptidase activity(GO:1902572)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 11.1 GO:0000801 central element(GO:0000801)
0.7 2.1 GO:0005588 collagen type V trimer(GO:0005588)
0.7 2.7 GO:0014802 terminal cisterna(GO:0014802)
0.7 5.4 GO:0008091 spectrin(GO:0008091)
0.7 2.7 GO:0000942 condensed nuclear chromosome outer kinetochore(GO:0000942)
0.6 9.6 GO:0008290 F-actin capping protein complex(GO:0008290)
0.5 8.1 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.4 2.2 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.4 1.1 GO:0042643 actomyosin, actin portion(GO:0042643)
0.3 2.8 GO:0033269 internode region of axon(GO:0033269)
0.3 1.5 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.3 3.0 GO:0019815 B cell receptor complex(GO:0019815)
0.3 2.9 GO:0042382 paraspeckles(GO:0042382)
0.3 1.6 GO:0071458 integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458) integral component of lumenal side of endoplasmic reticulum membrane(GO:0071556) lumenal side of endoplasmic reticulum membrane(GO:0098553)
0.3 3.0 GO:0034993 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.3 4.0 GO:0042555 MCM complex(GO:0042555)
0.2 1.5 GO:0031310 integral component of vacuolar membrane(GO:0031166) intrinsic component of vacuolar membrane(GO:0031310)
0.2 2.7 GO:0072687 meiotic spindle(GO:0072687)
0.2 0.9 GO:0008623 CHRAC(GO:0008623)
0.2 0.6 GO:0097361 CIA complex(GO:0097361)
0.2 12.3 GO:0015030 Cajal body(GO:0015030)
0.2 1.8 GO:0097255 R2TP complex(GO:0097255)
0.2 1.0 GO:0061673 mitotic spindle astral microtubule(GO:0061673)
0.2 1.6 GO:0005577 fibrinogen complex(GO:0005577)
0.1 1.0 GO:0097513 myosin II filament(GO:0097513)
0.1 3.8 GO:0031091 platelet alpha granule(GO:0031091)
0.1 1.8 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.1 2.0 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.1 0.9 GO:1990357 terminal web(GO:1990357)
0.1 0.9 GO:0005638 lamin filament(GO:0005638)
0.1 1.4 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.1 2.8 GO:0005859 muscle myosin complex(GO:0005859)
0.1 1.2 GO:0061700 GATOR2 complex(GO:0061700)
0.1 0.5 GO:0031262 Ndc80 complex(GO:0031262)
0.1 0.8 GO:0031673 H zone(GO:0031673)
0.1 0.5 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
0.1 0.3 GO:0036488 CHOP-C/EBP complex(GO:0036488) CHOP-ATF3 complex(GO:1990622)
0.1 1.0 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.1 0.7 GO:0071598 neuronal ribonucleoprotein granule(GO:0071598)
0.1 1.0 GO:0005677 chromatin silencing complex(GO:0005677)
0.1 0.8 GO:0072379 BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
0.1 0.3 GO:0099573 glutamatergic postsynaptic density(GO:0099573)
0.1 0.6 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
0.1 1.3 GO:0036038 MKS complex(GO:0036038)
0.1 0.8 GO:0000788 nuclear nucleosome(GO:0000788)
0.1 4.6 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.1 0.8 GO:0030670 phagocytic vesicle membrane(GO:0030670)
0.1 0.8 GO:0005642 annulate lamellae(GO:0005642)
0.1 1.4 GO:0000780 condensed nuclear chromosome, centromeric region(GO:0000780)
0.1 0.6 GO:0030015 CCR4-NOT core complex(GO:0030015)
0.1 0.2 GO:0043512 inhibin-betaglycan-ActRII complex(GO:0034673) inhibin A complex(GO:0043512)
0.0 2.8 GO:0097610 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 1.4 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 0.9 GO:0042405 nuclear inclusion body(GO:0042405)
0.0 1.1 GO:0071564 npBAF complex(GO:0071564)
0.0 0.2 GO:0070033 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032) synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex(GO:0070033)
0.0 0.4 GO:0070369 beta-catenin-TCF7L2 complex(GO:0070369)
0.0 0.1 GO:0002095 caveolar macromolecular signaling complex(GO:0002095)
0.0 0.4 GO:0061574 ASAP complex(GO:0061574)
0.0 1.1 GO:0071782 endoplasmic reticulum tubular network(GO:0071782) endoplasmic reticulum subcompartment(GO:0098827)
0.0 1.0 GO:0001891 phagocytic cup(GO:0001891)
0.0 0.5 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.0 1.6 GO:1990391 DNA repair complex(GO:1990391)
0.0 5.8 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)
0.0 0.2 GO:0070876 SOSS complex(GO:0070876)
0.0 3.8 GO:0005814 centriole(GO:0005814)
0.0 0.3 GO:0031618 nuclear pericentric heterochromatin(GO:0031618)
0.0 0.7 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.0 5.0 GO:0001650 fibrillar center(GO:0001650)
0.0 1.2 GO:0030665 clathrin-coated vesicle membrane(GO:0030665)
0.0 1.2 GO:0030673 axolemma(GO:0030673)
0.0 0.4 GO:0030014 CCR4-NOT complex(GO:0030014)
0.0 0.7 GO:0030992 intraciliary transport particle B(GO:0030992)
0.0 0.1 GO:0070937 CRD-mediated mRNA stability complex(GO:0070937)
0.0 1.3 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 0.3 GO:0005697 telomerase holoenzyme complex(GO:0005697)
0.0 0.2 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.0 0.3 GO:0036056 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.0 0.5 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.4 GO:0035145 exon-exon junction complex(GO:0035145)
0.0 0.1 GO:0070436 Grb2-EGFR complex(GO:0070436)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
2.5 12.3 GO:0008859 exoribonuclease II activity(GO:0008859)
2.0 5.9 GO:0046538 bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619) 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity(GO:0046538)
0.7 2.2 GO:0004373 glycogen (starch) synthase activity(GO:0004373)
0.6 1.7 GO:0005026 transforming growth factor beta receptor activity, type II(GO:0005026)
0.5 4.9 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.4 2.2 GO:0030618 transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618)
0.4 2.5 GO:0017077 oxidative phosphorylation uncoupler activity(GO:0017077)
0.4 9.6 GO:0042608 T cell receptor binding(GO:0042608)
0.4 1.8 GO:0004998 transferrin receptor activity(GO:0004998)
0.3 1.0 GO:0035939 microsatellite binding(GO:0035939)
0.3 5.4 GO:0016857 racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857)
0.3 9.8 GO:0005123 death receptor binding(GO:0005123)
0.3 1.6 GO:0061649 ubiquitinated histone binding(GO:0061649)
0.3 1.6 GO:0072345 NAADP-sensitive calcium-release channel activity(GO:0072345)
0.3 1.9 GO:0052723 inositol hexakisphosphate kinase activity(GO:0000828) inositol hexakisphosphate 5-kinase activity(GO:0000832) inositol hexakisphosphate 1-kinase activity(GO:0052723) inositol hexakisphosphate 3-kinase activity(GO:0052724)
0.3 1.5 GO:0003872 6-phosphofructokinase activity(GO:0003872)
0.3 1.8 GO:0010997 anaphase-promoting complex binding(GO:0010997)
0.3 1.1 GO:0005128 erythropoietin receptor binding(GO:0005128)
0.3 6.4 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.2 1.7 GO:0047179 platelet-activating factor acetyltransferase activity(GO:0047179)
0.2 1.8 GO:0043141 ATP-dependent 5'-3' DNA helicase activity(GO:0043141)
0.2 0.9 GO:0004711 ribosomal protein S6 kinase activity(GO:0004711)
0.2 0.6 GO:0004912 interleukin-3 receptor activity(GO:0004912) interleukin-3 binding(GO:0019978)
0.2 1.4 GO:0042799 histone methyltransferase activity (H4-K20 specific)(GO:0042799)
0.2 1.2 GO:0070728 leucine binding(GO:0070728)
0.2 5.4 GO:0030506 ankyrin binding(GO:0030506)
0.2 0.9 GO:0070892 lipoteichoic acid receptor activity(GO:0070892)
0.2 3.0 GO:0043495 protein anchor(GO:0043495)
0.2 0.5 GO:0010698 acetyltransferase activator activity(GO:0010698)
0.2 0.5 GO:0036004 GAF domain binding(GO:0036004)
0.2 1.6 GO:0045340 mercury ion binding(GO:0045340)
0.2 1.6 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.2 10.9 GO:0008307 structural constituent of muscle(GO:0008307)
0.2 2.4 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.1 1.0 GO:0019808 polyamine binding(GO:0019808)
0.1 1.4 GO:0051434 BH3 domain binding(GO:0051434)
0.1 2.1 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.1 3.6 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.1 4.0 GO:0004003 ATP-dependent DNA helicase activity(GO:0004003)
0.1 3.5 GO:0030332 cyclin binding(GO:0030332)
0.1 1.7 GO:0015197 peptide transporter activity(GO:0015197)
0.1 0.8 GO:0070644 vitamin D response element binding(GO:0070644)
0.1 0.7 GO:0061665 SUMO ligase activity(GO:0061665)
0.1 0.6 GO:0001226 RNA polymerase II transcription corepressor binding(GO:0001226)
0.1 3.0 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.1 1.6 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.1 5.2 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
0.1 1.8 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
0.1 2.2 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.1 0.7 GO:0034452 dynactin binding(GO:0034452)
0.1 0.8 GO:0008046 axon guidance receptor activity(GO:0008046)
0.1 0.6 GO:0043426 MRF binding(GO:0043426)
0.1 2.6 GO:0008198 ferrous iron binding(GO:0008198)
0.1 0.3 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
0.1 0.8 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.1 4.2 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
0.1 0.8 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.1 1.3 GO:0030275 LRR domain binding(GO:0030275)
0.1 1.8 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.1 1.4 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.1 0.5 GO:0004723 calcium-dependent protein serine/threonine phosphatase activity(GO:0004723)
0.1 2.3 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.1 0.6 GO:0035184 histone threonine kinase activity(GO:0035184)
0.1 0.3 GO:0030171 voltage-gated proton channel activity(GO:0030171)
0.0 0.9 GO:0005521 lamin binding(GO:0005521)
0.0 1.0 GO:0051011 microtubule minus-end binding(GO:0051011)
0.0 1.0 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.0 0.8 GO:1990381 ubiquitin-specific protease binding(GO:1990381)
0.0 0.3 GO:1990247 N6-methyladenosine-containing RNA binding(GO:1990247)
0.0 0.9 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0 0.2 GO:0098821 BMP receptor activity(GO:0098821)
0.0 1.1 GO:0048156 tau protein binding(GO:0048156)
0.0 5.1 GO:0003697 single-stranded DNA binding(GO:0003697)
0.0 0.5 GO:0048185 activin binding(GO:0048185)
0.0 1.7 GO:0032452 histone demethylase activity(GO:0032452)
0.0 0.2 GO:0008294 calcium- and calmodulin-responsive adenylate cyclase activity(GO:0008294)
0.0 1.3 GO:0043015 gamma-tubulin binding(GO:0043015)
0.0 0.5 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0 0.7 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.0 0.9 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 0.5 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.0 3.5 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.0 1.0 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.0 0.4 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.0 0.2 GO:0016721 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.0 0.2 GO:0034711 inhibin binding(GO:0034711)
0.0 0.5 GO:0008432 JUN kinase binding(GO:0008432)
0.0 0.2 GO:0098519 nucleotide phosphatase activity, acting on free nucleotides(GO:0098519)
0.0 1.2 GO:0016831 carboxy-lyase activity(GO:0016831)
0.0 0.7 GO:0008536 Ran GTPase binding(GO:0008536)
0.0 0.4 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.0 0.1 GO:0086056 voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056)
0.0 0.2 GO:0005041 low-density lipoprotein receptor activity(GO:0005041)
0.0 0.6 GO:0008143 poly(A) binding(GO:0008143)
0.0 0.3 GO:0035497 cAMP response element binding(GO:0035497)
0.0 0.2 GO:0034713 type I transforming growth factor beta receptor binding(GO:0034713)
0.0 0.3 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.0 2.0 GO:0032947 protein complex scaffold(GO:0032947)
0.0 1.1 GO:0004004 RNA helicase activity(GO:0003724) ATP-dependent RNA helicase activity(GO:0004004) ATP-dependent helicase activity(GO:0008026) RNA-dependent ATPase activity(GO:0008186) purine NTP-dependent helicase activity(GO:0070035)
0.0 0.4 GO:0045295 gamma-catenin binding(GO:0045295)
0.0 0.1 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.0 0.1 GO:0004008 copper-exporting ATPase activity(GO:0004008) copper-transporting ATPase activity(GO:0043682)
0.0 0.1 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.0 0.2 GO:0042731 PH domain binding(GO:0042731)
0.0 1.2 GO:0003725 double-stranded RNA binding(GO:0003725)
0.0 0.2 GO:0045028 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.0 0.8 GO:0004536 deoxyribonuclease activity(GO:0004536)
0.0 2.1 GO:0008201 heparin binding(GO:0008201)
0.0 0.8 GO:0016836 hydro-lyase activity(GO:0016836)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 17.5 PID PLK1 PATHWAY PLK1 signaling events
0.1 1.5 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.1 4.7 PID P38 ALPHA BETA PATHWAY Regulation of p38-alpha and p38-beta
0.1 2.8 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.1 4.0 PID ATR PATHWAY ATR signaling pathway
0.1 5.8 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.1 1.6 PID LYMPH ANGIOGENESIS PATHWAY VEGFR3 signaling in lymphatic endothelium
0.1 2.4 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.1 1.8 PID MYC PATHWAY C-MYC pathway
0.1 1.4 PID FGF PATHWAY FGF signaling pathway
0.1 4.3 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.1 3.3 PID ARF6 TRAFFICKING PATHWAY Arf6 trafficking events
0.1 1.0 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.1 4.5 PID INTEGRIN1 PATHWAY Beta1 integrin cell surface interactions
0.1 1.6 PID GLYPICAN 1PATHWAY Glypican 1 network
0.0 4.5 PID E2F PATHWAY E2F transcription factor network
0.0 0.6 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.0 0.6 PID IL3 PATHWAY IL3-mediated signaling events
0.0 2.4 PID BMP PATHWAY BMP receptor signaling
0.0 1.0 PID NECTIN PATHWAY Nectin adhesion pathway
0.0 1.7 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.0 0.9 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.0 2.6 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.0 1.1 PID ERBB2 ERBB3 PATHWAY ErbB2/ErbB3 signaling events
0.0 1.4 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.0 0.8 PID FOXM1 PATHWAY FOXM1 transcription factor network
0.0 0.4 PID EPHA FWDPATHWAY EPHA forward signaling
0.0 1.3 PID ILK PATHWAY Integrin-linked kinase signaling
0.0 0.3 PID ATM PATHWAY ATM pathway
0.0 1.4 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.0 0.7 PID HDAC CLASSI PATHWAY Signaling events mediated by HDAC Class I
0.0 0.4 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.0 1.0 PID CASPASE PATHWAY Caspase cascade in apoptosis

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.7 REACTOME CIRCADIAN CLOCK Genes involved in Circadian Clock
0.3 9.6 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.3 4.0 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.2 7.0 REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
0.2 12.3 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.2 2.7 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.2 8.1 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.1 1.0 REACTOME RETROGRADE NEUROTROPHIN SIGNALLING Genes involved in Retrograde neurotrophin signalling
0.1 14.4 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.1 5.4 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.1 3.8 REACTOME EGFR DOWNREGULATION Genes involved in EGFR downregulation
0.1 2.0 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.1 4.7 REACTOME G1 PHASE Genes involved in G1 Phase
0.1 1.6 REACTOME GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTERGRINS Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins
0.1 3.9 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.1 3.0 REACTOME INTERFERON GAMMA SIGNALING Genes involved in Interferon gamma signaling
0.1 3.0 REACTOME IL1 SIGNALING Genes involved in Interleukin-1 signaling
0.1 1.0 REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES Genes involved in Recruitment of NuMA to mitotic centrosomes
0.1 1.4 REACTOME INFLAMMASOMES Genes involved in Inflammasomes
0.1 0.9 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1
0.1 1.0 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.1 2.4 REACTOME MEIOTIC SYNAPSIS Genes involved in Meiotic Synapsis
0.0 1.8 REACTOME TELOMERE MAINTENANCE Genes involved in Telomere Maintenance
0.0 1.8 REACTOME TRANSFERRIN ENDOCYTOSIS AND RECYCLING Genes involved in Transferrin endocytosis and recycling
0.0 1.1 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0 0.9 REACTOME PROCESSING OF INTRONLESS PRE MRNAS Genes involved in Processing of Intronless Pre-mRNAs
0.0 1.0 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0 0.8 REACTOME PLATELET CALCIUM HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.0 0.8 REACTOME ARMS MEDIATED ACTIVATION Genes involved in ARMS-mediated activation
0.0 0.6 REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS Genes involved in Trafficking of GluR2-containing AMPA receptors
0.0 0.7 REACTOME ACTIVATION OF GENES BY ATF4 Genes involved in Activation of Genes by ATF4
0.0 0.9 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.0 0.3 REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.0 1.8 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 0.5 REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.0 2.9 REACTOME PPARA ACTIVATES GENE EXPRESSION Genes involved in PPARA Activates Gene Expression
0.0 1.1 REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0 0.3 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0 0.6 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 0.5 REACTOME KINESINS Genes involved in Kinesins
0.0 2.4 REACTOME SRP DEPENDENT COTRANSLATIONAL PROTEIN TARGETING TO MEMBRANE Genes involved in SRP-dependent cotranslational protein targeting to membrane
0.0 0.7 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.0 0.9 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0 0.5 REACTOME LYSOSOME VESICLE BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis
0.0 0.2 REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY Genes involved in Adenylate cyclase activating pathway
0.0 0.6 REACTOME IL RECEPTOR SHC SIGNALING Genes involved in Interleukin receptor SHC signaling
0.0 0.2 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.0 0.2 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors