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GSE58827: Dynamics of the Mouse Liver

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Results for Pitx3

Z-value: 0.74

Motif logo

Transcription factors associated with Pitx3

Gene Symbol Gene ID Gene Info
ENSMUSG00000025229.16 paired-like homeodomain transcription factor 3

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Pitx3mm39_v1_chr19_-_46136765_46136825-0.511.4e-03Click!

Activity profile of Pitx3 motif

Sorted Z-values of Pitx3 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr5_+_90638580 12.26 ENSMUST00000042755.7
ENSMUST00000200693.2
alpha fetoprotein
chr9_+_110248815 9.45 ENSMUST00000035061.9
neutrophilic granule protein
chr16_+_36004452 8.04 ENSMUST00000114858.2
cystatin domain containing 4
chr10_+_79722081 7.09 ENSMUST00000046091.7
elastase, neutrophil expressed
chr10_+_128736827 6.91 ENSMUST00000219317.2
CD63 antigen
chr7_-_143013899 5.48 ENSMUST00000208137.2
ENSMUST00000207910.2
cyclin-dependent kinase inhibitor 1C (P57)
chr7_-_143014726 5.44 ENSMUST00000167912.9
ENSMUST00000037287.8
cyclin-dependent kinase inhibitor 1C (P57)
chr8_+_85628557 4.59 ENSMUST00000067060.10
ENSMUST00000239392.2
Kruppel-like factor 1 (erythroid)
chr10_+_128744689 4.53 ENSMUST00000105229.9
CD63 antigen
chr3_-_36626101 4.31 ENSMUST00000029270.10
cyclin A2
chr2_-_32278245 3.79 ENSMUST00000192241.2
lipocalin 2
chr9_-_70328816 3.77 ENSMUST00000034742.8
cyclin B2
chr11_-_6470918 3.72 ENSMUST00000003459.4
myosin IG
chr15_-_78739717 3.66 ENSMUST00000044584.6
lectin, galactose-binding, soluble 2
chr6_-_88875646 3.58 ENSMUST00000058011.8
minichromosome maintenance complex component 2
chr7_-_45173193 3.31 ENSMUST00000211212.2
protein phosphatase 1, regulatory subunit 15A
chr6_-_115739284 3.23 ENSMUST00000166254.7
ENSMUST00000170625.8
transmembrane protein 40
chr11_+_117673107 3.20 ENSMUST00000050874.14
ENSMUST00000106334.9
transmembrane channel-like gene family 8
chr10_-_62178453 3.18 ENSMUST00000143179.2
ENSMUST00000130422.8
hexokinase 1
chr7_-_45175570 3.17 ENSMUST00000167273.2
ENSMUST00000042105.11
protein phosphatase 1, regulatory subunit 15A
chr17_-_35407403 3.05 ENSMUST00000097336.5
leukocyte specific transcript 1
chr11_-_116472272 3.04 ENSMUST00000082152.5
ubiquitin-conjugating enzyme E2O
chr2_+_91376650 3.00 ENSMUST00000099716.11
ENSMUST00000046769.16
ENSMUST00000111337.3
cytoskeleton associated protein 5
chr9_-_107863062 3.00 ENSMUST00000048568.6
inka box actin regulator 1
chr11_-_97886997 2.91 ENSMUST00000042971.16
ADP-ribosylation factor-like 5C
chr14_-_70867588 2.90 ENSMUST00000228009.2
dematin actin binding protein
chr15_-_82128888 2.79 ENSMUST00000089155.6
ENSMUST00000089157.11
centromere protein M
chr2_-_165242307 2.70 ENSMUST00000029213.5
osteoclast stimulatory transmembrane protein
chr11_+_61847589 2.62 ENSMUST00000201671.4
ENSMUST00000202178.4
sperm antigen with calponin homology and coiled-coil domains 1
chr11_-_106889291 2.62 ENSMUST00000124541.8
karyopherin (importin) alpha 2
chr7_+_28140352 2.54 ENSMUST00000078845.13
glia maturation factor, gamma
chrX_-_9335525 2.40 ENSMUST00000015484.10
cytochrome b-245, beta polypeptide
chr17_+_56259617 2.36 ENSMUST00000003274.8
Epstein-Barr virus induced gene 3
chrX_-_137985960 2.29 ENSMUST00000033626.15
ENSMUST00000060824.4
serine (or cysteine) peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 7
chr15_+_6451721 2.24 ENSMUST00000163082.2
disabled 2, mitogen-responsive phosphoprotein
chr18_+_34869412 2.24 ENSMUST00000105038.3
predicted gene 3550
chr14_+_31888061 2.22 ENSMUST00000164341.2
nuclear receptor coactivator 4
chr5_-_100720063 2.22 ENSMUST00000031264.12
placenta-specific 8
chrX_-_137985979 2.20 ENSMUST00000152457.2
serine (or cysteine) peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 7
chr6_+_86605146 2.11 ENSMUST00000043400.9
aspartic peptidase, retroviral-like 1
chr10_+_20223516 2.06 ENSMUST00000169712.3
ENSMUST00000217608.2
mitochondrial fission regulator 2
chr16_-_8610165 2.05 ENSMUST00000160405.8
ubiquitin specific peptidase 7
chr16_-_36154692 2.04 ENSMUST00000114850.3
cystatin domain containing 6
chr7_+_28140450 1.98 ENSMUST00000135686.2
glia maturation factor, gamma
chr3_+_107137924 1.97 ENSMUST00000179399.3
RIKEN cDNA A630076J17 gene
chr9_+_103182352 1.93 ENSMUST00000035164.10
topoisomerase (DNA) II binding protein 1
chrX_-_7956682 1.92 ENSMUST00000033505.7
Wiskott-Aldrich syndrome
chr17_+_29333116 1.89 ENSMUST00000233717.2
ENSMUST00000141239.2
RAB44, member RAS oncogene family
chr7_+_140711181 1.89 ENSMUST00000026568.10
phosphatidylserine synthase 2
chr10_+_62782786 1.89 ENSMUST00000131422.8
DNA replication helicase/nuclease 2
chr3_-_105839980 1.86 ENSMUST00000098758.5
RIKEN cDNA I830077J02 gene
chr11_+_61847622 1.82 ENSMUST00000202389.4
sperm antigen with calponin homology and coiled-coil domains 1
chr6_+_34331054 1.80 ENSMUST00000038406.7
aldo-keto reductase family 1, member B8
chr18_+_35932894 1.79 ENSMUST00000236484.2
ENSMUST00000236550.2
ENSMUST00000235919.2
ubiquitin-conjugating enzyme E2D 2A
predicted gene, 50371
chr8_-_124709859 1.79 ENSMUST00000075578.7
ATP-binding cassette, sub-family B (MDR/TAP), member 10
chr17_-_25946370 1.79 ENSMUST00000170070.3
ENSMUST00000048054.14
CTF18, chromosome transmission fidelity factor 18
chr17_-_26163906 1.79 ENSMUST00000085027.4
ENSMUST00000237570.2
NHL repeat containing 4
phosphatidylinositol glycan anchor biosynthesis, class Q
chr6_-_113412708 1.76 ENSMUST00000032416.11
ENSMUST00000113089.8
cell death-inducing DFFA-like effector c
chr7_-_133304244 1.76 ENSMUST00000209636.2
ENSMUST00000153698.3
uroporphyrinogen III synthase
chr7_-_19410749 1.71 ENSMUST00000003074.16
apolipoprotein C-II
chr17_+_6697511 1.69 ENSMUST00000179569.3
dynein light chain Tctex-type 1B
chr14_-_47655621 1.68 ENSMUST00000180299.8
DLG associated protein 5
chr17_-_6923299 1.65 ENSMUST00000179554.3
dynein light chain Tctex-type 1F
chr3_+_129672205 1.65 ENSMUST00000029629.15
phospholipase A2, group XIIA
chr7_-_6699422 1.62 ENSMUST00000122432.4
ENSMUST00000002336.16
zinc finger, imprinted 1
chr15_-_99268311 1.60 ENSMUST00000081224.14
ENSMUST00000120633.2
ENSMUST00000088233.13
formin-like 3
chr9_+_72345267 1.60 ENSMUST00000183809.8
meiosis-specific nuclear structural protein 1
chr17_+_36172210 1.59 ENSMUST00000074259.15
ENSMUST00000174873.2
nurim (nuclear envelope membrane protein)
chr4_-_149221998 1.54 ENSMUST00000176124.8
ENSMUST00000177408.2
ENSMUST00000105695.2
centromere protein S
chr17_+_29712008 1.54 ENSMUST00000234665.2
proviral integration site 1
chr2_-_34645241 1.52 ENSMUST00000102800.9
GTPase activating protein and VPS9 domains 1
chr2_-_121304521 1.50 ENSMUST00000056732.4
microfibrillar-associated protein 1B
chr11_+_32155415 1.48 ENSMUST00000039601.10
ENSMUST00000149043.3
small nuclear ribonucleoprotein 25 (U11/U12)
chr9_+_118335294 1.48 ENSMUST00000084820.6
golgi autoantigen, golgin subfamily a, 4
chr4_-_116485118 1.43 ENSMUST00000030456.14
nuclear autoantigenic sperm protein (histone-binding)
chr4_+_132903646 1.42 ENSMUST00000105912.2
WASP family, member 2
chr7_-_100164007 1.42 ENSMUST00000207405.2
DnaJ heat shock protein family (Hsp40) member B13
chr17_+_6869070 1.42 ENSMUST00000092966.5
dynein light chain Tctex-type 1C
chr15_-_82128538 1.41 ENSMUST00000229747.2
ENSMUST00000230408.2
centromere protein M
chr1_-_153363354 1.41 ENSMUST00000186380.7
ENSMUST00000188345.2
ENSMUST00000042141.12
DEAH (Asp-Glu-Ala-His) box polypeptide 9
chr7_-_24997393 1.41 ENSMUST00000005583.12
platelet-activating factor acetylhydrolase, isoform 1b, subunit 3
chr6_-_143045731 1.40 ENSMUST00000203673.3
ENSMUST00000203187.3
ENSMUST00000171349.8
ENSMUST00000087485.7
C2 calcium-dependent domain containing 5
chr9_-_107512511 1.39 ENSMUST00000192615.6
ENSMUST00000192837.2
ENSMUST00000193876.2
guanine nucleotide binding protein (G protein), alpha inhibiting 2
chr5_-_137609634 1.38 ENSMUST00000054564.13
procollagen C-endopeptidase enhancer protein
chr7_+_16726633 1.38 ENSMUST00000094805.5
coiled-coil domain containing 8
chr11_-_120238917 1.37 ENSMUST00000106215.11
actin, gamma, cytoplasmic 1
chr5_+_110478558 1.37 ENSMUST00000112481.2
polymerase (DNA directed), epsilon
chr7_-_30119227 1.37 ENSMUST00000208740.2
ENSMUST00000075062.5
hematopoietic cell signal transducer
chr16_+_31241085 1.35 ENSMUST00000089759.9
3-hydroxybutyrate dehydrogenase, type 1
chr1_-_153425791 1.35 ENSMUST00000041874.9
N-acetylneuraminate pyruvate lyase
chr4_+_154096188 1.34 ENSMUST00000169622.8
ENSMUST00000030894.15
leucine rich repeat containing 47
chr10_+_128073900 1.34 ENSMUST00000105245.3
timeless circadian clock 1
chr15_+_97682210 1.33 ENSMUST00000117892.2
ENSMUST00000229084.2
solute carrier family 48 (heme transporter), member 1
chr7_-_19504446 1.33 ENSMUST00000003061.14
basal cell adhesion molecule
chr4_-_149222057 1.32 ENSMUST00000030813.10
centromere protein S
chr9_+_15217548 1.30 ENSMUST00000215124.2
ENSMUST00000164079.9
ENSMUST00000216109.2
TATA-box binding protein associated factor, RNA polymerase I, D
chr5_-_137609691 1.29 ENSMUST00000031731.14
procollagen C-endopeptidase enhancer protein
chr8_+_61343444 1.29 ENSMUST00000146863.2
ENSMUST00000037190.15
histone PARylation factor 1
chr9_-_107512566 1.28 ENSMUST00000055704.12
guanine nucleotide binding protein (G protein), alpha inhibiting 2
chr4_-_117013396 1.27 ENSMUST00000102696.5
ribosomal protein S8
chr5_+_117271632 1.27 ENSMUST00000179276.8
ENSMUST00000092889.12
ENSMUST00000145640.8
TAO kinase 3
chr7_-_24997291 1.27 ENSMUST00000148150.8
ENSMUST00000155118.2
platelet-activating factor acetylhydrolase, isoform 1b, subunit 3
chr8_-_84467798 1.24 ENSMUST00000075843.13
ENSMUST00000109802.3
ENSMUST00000166939.8
ENSMUST00000002964.14
adhesion G protein-coupled receptor E5
chr10_-_93725619 1.23 ENSMUST00000181091.8
ENSMUST00000181217.8
ENSMUST00000047910.15
ENSMUST00000180688.2
methionine aminopeptidase 2
chr18_-_34784746 1.23 ENSMUST00000025228.12
ENSMUST00000133181.2
CDC23 cell division cycle 23
chr10_-_62628008 1.22 ENSMUST00000217768.2
ENSMUST00000020268.7
ENSMUST00000218946.2
ENSMUST00000219527.2
cell division cycle and apoptosis regulator 1
chr11_-_117673008 1.22 ENSMUST00000152304.3
transmembrane channel-like gene family 6
chr1_+_92900834 1.21 ENSMUST00000186298.7
ENSMUST00000027489.9
G protein-coupled receptor 35
chr7_+_19024994 1.21 ENSMUST00000108468.5
reticulon 2 (Z-band associated protein)
chr1_+_85538554 1.21 ENSMUST00000162925.2
Sp140 nuclear body protein
chr4_+_156194427 1.21 ENSMUST00000072554.13
ENSMUST00000169550.8
ENSMUST00000105576.2
RIKEN cDNA 9430015G10 gene
chr12_-_28685849 1.20 ENSMUST00000221871.2
ribosomal protein S7
chr5_-_129856267 1.19 ENSMUST00000201394.4
phosphoserine phosphatase
chr7_-_33867940 1.19 ENSMUST00000102746.11
ubiquitin-like modifier activating enzyme 2
chr5_-_100126773 1.19 ENSMUST00000112939.10
ENSMUST00000171786.8
ENSMUST00000072750.13
ENSMUST00000019128.15
ENSMUST00000172361.8
heterogeneous nuclear ribonucleoprotein D
chr2_+_127050281 1.17 ENSMUST00000103220.4
small nuclear ribonucleoprotein 200 (U5)
chr7_+_27967222 1.16 ENSMUST00000059596.8
EP300 interacting inhibitor of differentiation 2
chr19_+_8870362 1.15 ENSMUST00000096249.7
integrator complex subunit 5
chr7_-_15701395 1.15 ENSMUST00000144956.2
ENSMUST00000098799.5
EH-domain containing 2
chr7_+_12631727 1.15 ENSMUST00000055528.11
ENSMUST00000117189.2
ENSMUST00000120809.2
ENSMUST00000119989.3
zinc finger and SCAN domain containing 22
chr3_+_89979948 1.15 ENSMUST00000121503.8
ENSMUST00000119570.8
tropomyosin 3, gamma
chr8_+_95393228 1.14 ENSMUST00000034228.16
ADP-ribosylation factor-like 2 binding protein
chr5_+_108048367 1.13 ENSMUST00000082223.13
ribosomal protein L5
chr2_+_128942919 1.13 ENSMUST00000028874.8
polymerase (RNA) I polypeptide B
chr7_+_127503251 1.11 ENSMUST00000071056.14
branched chain ketoacid dehydrogenase kinase
chr6_+_40941688 1.11 ENSMUST00000076638.7
RIKEN cDNA 1810009J06 gene
chr8_-_120296734 1.11 ENSMUST00000212517.2
hydroxysteroid dehydrogenase like 1
chr8_+_72994152 1.11 ENSMUST00000126885.2
adaptor-related protein complex AP-1, mu subunit 1
chr11_-_103247150 1.11 ENSMUST00000136491.3
ENSMUST00000107023.3
Rho GTPase activating protein 27
chr11_-_121120052 1.10 ENSMUST00000169393.8
ENSMUST00000106115.8
ENSMUST00000038709.14
ENSMUST00000147490.6
cytochrome b 245 chaperone 1
chr2_-_163486998 1.10 ENSMUST00000017851.4
serine incorporator 3
chr17_-_33932346 1.10 ENSMUST00000173392.2
membrane associated ring-CH-type finger 2
chr5_-_116162415 1.09 ENSMUST00000031486.14
ENSMUST00000111999.8
protein kinase, AMP-activated, beta 1 non-catalytic subunit
chr2_-_5900130 1.08 ENSMUST00000026926.5
ENSMUST00000193792.6
ENSMUST00000102981.10
Sec61, alpha subunit 2 (S. cerevisiae)
chr5_+_130058119 1.07 ENSMUST00000026608.11
ENSMUST00000202163.4
ENSMUST00000202756.2
calcitonin gene-related peptide-receptor component protein
chr11_+_68906737 1.07 ENSMUST00000021278.14
ENSMUST00000161455.8
ENSMUST00000116359.3
CTS telomere maintenance complex component 1
chr14_-_99231754 1.07 ENSMUST00000081987.5
ribosomal protein L36A, pseudogene 1
chr5_-_92457862 1.07 ENSMUST00000031364.5
SDA1 domain containing 1
chr12_-_28685913 1.06 ENSMUST00000074267.5
ribosomal protein S7
chr6_+_42326714 1.06 ENSMUST00000203846.3
zyxin
chr10_+_7543260 1.06 ENSMUST00000040135.9
nucleoporin 43
chr8_-_11685726 1.06 ENSMUST00000033905.13
ENSMUST00000169782.3
ankyrin repeat domain 10
chr6_-_131270136 1.06 ENSMUST00000032307.12
mago homolog B, exon junction complex core component
chr18_-_74340842 1.05 ENSMUST00000040188.16
spindle and kinetochore associated complex subunit 1
chr17_+_36172235 1.05 ENSMUST00000172931.2
nurim (nuclear envelope membrane protein)
chr10_-_40178182 1.05 ENSMUST00000099945.6
ENSMUST00000238953.2
ENSMUST00000238969.2
S-adenosylmethionine decarboxylase 1
chr9_-_78396407 1.04 ENSMUST00000154207.8
eukaryotic translation elongation factor 1 alpha 1
chr11_-_115918784 1.04 ENSMUST00000106454.8
H3.3 histone B
chr14_+_31881822 1.04 ENSMUST00000163336.8
ENSMUST00000169722.8
ENSMUST00000168385.8
nuclear receptor coactivator 4
chr9_-_114811807 1.02 ENSMUST00000053150.8
ribosomal protein S27, retrogene
chr11_+_117673198 1.02 ENSMUST00000117781.8
transmembrane channel-like gene family 8
chr16_+_17051423 1.01 ENSMUST00000090190.14
ENSMUST00000232082.2
ENSMUST00000232426.2
hypermethylated in cancer 2
predicted gene, 49573
chr19_-_17316906 1.00 ENSMUST00000169897.2
glucosaminyl (N-acetyl) transferase 1, core 2
chr14_+_47710005 1.00 ENSMUST00000043112.9
ENSMUST00000163324.8
ENSMUST00000228668.2
ENSMUST00000168833.9
F-box protein 34
chr10_+_58230203 0.99 ENSMUST00000105468.2
LIM and senescent cell antigen-like domains 1
chr9_+_21231994 0.98 ENSMUST00000217461.2
solute carrier family 44, member 2
chr12_+_83572774 0.98 ENSMUST00000223291.2
DDB1 and CUL4 associated factor 4
chr12_-_69205882 0.98 ENSMUST00000037023.9
ribosomal protein S29
chr2_+_128942900 0.97 ENSMUST00000103205.11
polymerase (RNA) I polypeptide B
chr7_-_4448631 0.97 ENSMUST00000008579.14
retinol dehydrogenase 13 (all-trans and 9-cis)
chr7_-_117715394 0.97 ENSMUST00000131374.8
ribosomal protein S15A
chr7_-_47178610 0.97 ENSMUST00000172559.2
MAS-related GPR, member A2B
chr10_+_79832313 0.96 ENSMUST00000132517.8
ATP-binding cassette, sub-family A (ABC1), member 7
chr6_+_42326934 0.96 ENSMUST00000203401.3
ENSMUST00000164375.4
zyxin
chr15_+_102391614 0.96 ENSMUST00000229432.2
poly(rC) binding protein 2
chr1_-_55066629 0.95 ENSMUST00000027127.14
splicing factor 3b, subunit 1
chr19_-_32188413 0.95 ENSMUST00000151289.9
sphingomyelin synthase 1
chr16_+_16844217 0.95 ENSMUST00000232067.2
mitogen-activated protein kinase 1
chr5_-_129856237 0.94 ENSMUST00000118268.9
phosphoserine phosphatase
chr16_-_4536992 0.94 ENSMUST00000115851.10
NmrA-like family domain containing 1
chr13_-_38842967 0.94 ENSMUST00000001757.9
eukaryotic translation elongation factor 1 epsilon 1
chr16_-_4536943 0.94 ENSMUST00000120056.8
ENSMUST00000074970.8
NmrA-like family domain containing 1
chr11_+_96822213 0.93 ENSMUST00000107633.2
proline rich 15-like
chr5_-_36853281 0.92 ENSMUST00000031091.13
ENSMUST00000140653.2
DNA segment, Chr 5, ERATO Doi 579, expressed
chr5_-_92457753 0.92 ENSMUST00000201143.2
SDA1 domain containing 1
chr17_-_66175046 0.91 ENSMUST00000233399.2
ralA binding protein 1
chr3_+_30910089 0.91 ENSMUST00000108261.8
ENSMUST00000108259.8
ENSMUST00000166278.7
ENSMUST00000046748.13
ENSMUST00000194979.6
G protein-coupled receptor 160
chr12_-_79027531 0.91 ENSMUST00000174072.8
transmembrane protein 229B
chr16_-_22084700 0.90 ENSMUST00000161286.8
transformer 2 beta
chr10_+_58230183 0.90 ENSMUST00000020077.11
LIM and senescent cell antigen-like domains 1
chr15_+_102387053 0.89 ENSMUST00000230682.2
ENSMUST00000231085.2
poly(rC) binding protein 2
chr5_-_134485430 0.89 ENSMUST00000200944.4
ENSMUST00000202280.4
ENSMUST00000074114.12
ENSMUST00000100654.10
ENSMUST00000100650.10
ENSMUST00000111245.9
ENSMUST00000202554.4
ENSMUST00000073161.12
ENSMUST00000100652.10
ENSMUST00000171794.9
ENSMUST00000167084.9
general transcription factor II I repeat domain-containing 1
chr9_+_69902697 0.88 ENSMUST00000165389.8
BCL2/adenovirus E1B interacting protein 2
chr9_+_64868127 0.87 ENSMUST00000170517.9
ENSMUST00000037504.7
integrator complex subunit 14
chr11_-_78074377 0.87 ENSMUST00000102483.5
ribosomal protein L23A
chr11_-_106890195 0.86 ENSMUST00000106768.2
ENSMUST00000144834.8
karyopherin (importin) alpha 2
chr5_+_115697526 0.86 ENSMUST00000086519.12
ENSMUST00000156359.2
ENSMUST00000152976.2
ribosomal protein, large, P0
chrX_+_162923474 0.86 ENSMUST00000073973.11
angiotensin I converting enzyme (peptidyl-dipeptidase A) 2
chr3_+_95434093 0.86 ENSMUST00000015667.9
ENSMUST00000116304.3
cathepsin S
chr13_-_101829132 0.86 ENSMUST00000035532.13
phosphoinositide-3-kinase regulatory subunit 1
chr7_-_126831803 0.85 ENSMUST00000133913.8
septin 1
chr8_+_26210484 0.85 ENSMUST00000210629.2
phospholipid phosphatase 5
chr2_+_31985528 0.84 ENSMUST00000057423.6
ENSMUST00000140762.2
phospholipid phosphatase 7 (inactive)
chr11_+_88861073 0.82 ENSMUST00000107898.8
coilin
chr15_+_99600149 0.81 ENSMUST00000229236.2
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1
chr6_+_42326760 0.81 ENSMUST00000203652.3
ENSMUST00000070635.13
zyxin
chr6_-_120334382 0.81 ENSMUST00000032283.12
coiled-coil domain containing 77
chr5_+_66018555 0.80 ENSMUST00000031106.8
ras homolog family member H
chr9_+_15217503 0.80 ENSMUST00000034415.6
TATA-box binding protein associated factor, RNA polymerase I, D
chr15_+_95698574 0.79 ENSMUST00000226793.2
anoctamin 6

Network of associatons between targets according to the STRING database.

First level regulatory network of Pitx3

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
2.4 7.1 GO:0002777 antimicrobial peptide biosynthetic process(GO:0002777) antibacterial peptide biosynthetic process(GO:0002780) neutrophil mediated killing of fungus(GO:0070947)
2.4 9.5 GO:1901491 negative regulation of lymphangiogenesis(GO:1901491)
2.2 6.5 GO:0060734 regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation(GO:0060734)
1.9 11.4 GO:2000680 regulation of rubidium ion transport(GO:2000680)
1.5 4.5 GO:0071846 actin filament debranching(GO:0071846)
1.5 4.5 GO:0033189 response to vitamin A(GO:0033189)
1.3 3.8 GO:0015688 iron chelate transport(GO:0015688) siderophore transport(GO:0015891)
1.0 10.7 GO:1902746 regulation of lens fiber cell differentiation(GO:1902746)
0.7 12.3 GO:0001542 ovulation from ovarian follicle(GO:0001542)
0.7 2.9 GO:0038096 immune response-regulating cell surface receptor signaling pathway involved in phagocytosis(GO:0002433) Fc-gamma receptor signaling pathway involved in phagocytosis(GO:0038096)
0.7 2.7 GO:0034241 positive regulation of macrophage fusion(GO:0034241) positive regulation of osteoclast proliferation(GO:0090290)
0.6 1.9 GO:0002625 regulation of T cell antigen processing and presentation(GO:0002625)
0.6 1.8 GO:0006714 sesquiterpenoid metabolic process(GO:0006714)
0.6 1.8 GO:0006780 uroporphyrinogen III biosynthetic process(GO:0006780)
0.5 2.1 GO:0017126 nucleologenesis(GO:0017126)
0.5 3.0 GO:0030951 establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951)
0.5 2.9 GO:0035585 calcium-mediated signaling using extracellular calcium source(GO:0035585)
0.5 1.9 GO:1902990 mitotic telomere maintenance via semi-conservative replication(GO:1902990)
0.5 1.4 GO:0006272 leading strand elongation(GO:0006272) DNA replication proofreading(GO:0045004)
0.4 1.3 GO:0002545 chronic inflammatory response to non-antigenic stimulus(GO:0002545) regulation of chronic inflammatory response to non-antigenic stimulus(GO:0002880)
0.4 1.3 GO:0018312 peptidyl-serine ADP-ribosylation(GO:0018312)
0.4 1.7 GO:0060697 positive regulation of phospholipid catabolic process(GO:0060697)
0.4 2.0 GO:0035616 histone H2B conserved C-terminal lysine deubiquitination(GO:0035616)
0.4 1.2 GO:1904456 negative regulation of neuronal action potential(GO:1904456)
0.4 1.2 GO:0007181 transforming growth factor beta receptor complex assembly(GO:0007181)
0.4 1.1 GO:1903632 positive regulation of aminoacyl-tRNA ligase activity(GO:1903632)
0.4 2.2 GO:0035026 leading edge cell differentiation(GO:0035026)
0.4 1.1 GO:0042275 error-free postreplication DNA repair(GO:0042275)
0.4 1.4 GO:1904158 axonemal central apparatus assembly(GO:1904158)
0.4 2.8 GO:0061718 NADH regeneration(GO:0006735) canonical glycolysis(GO:0061621) glucose catabolic process to pyruvate(GO:0061718)
0.3 1.0 GO:0006597 spermine biosynthetic process(GO:0006597)
0.3 1.7 GO:1901355 response to rapamycin(GO:1901355)
0.3 2.7 GO:0097411 hypoxia-inducible factor-1alpha signaling pathway(GO:0097411)
0.3 1.0 GO:1901074 regulation of engulfment of apoptotic cell(GO:1901074)
0.3 3.6 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.3 1.5 GO:0015965 diadenosine polyphosphate biosynthetic process(GO:0015960) diadenosine tetraphosphate metabolic process(GO:0015965) diadenosine tetraphosphate biosynthetic process(GO:0015966)
0.3 1.2 GO:2001137 positive regulation of endocytic recycling(GO:2001137)
0.3 0.9 GO:0034769 basement membrane disassembly(GO:0034769)
0.3 1.4 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
0.3 1.9 GO:0006659 phosphatidylserine biosynthetic process(GO:0006659)
0.3 1.3 GO:1904975 response to bleomycin(GO:1904975) cellular response to bleomycin(GO:1904976)
0.3 2.1 GO:0006564 L-serine biosynthetic process(GO:0006564)
0.3 0.8 GO:0002543 activation of blood coagulation via clotting cascade(GO:0002543) phosphatidylserine exposure on blood platelet(GO:0097045)
0.3 0.8 GO:1902626 assembly of large subunit precursor of preribosome(GO:1902626)
0.2 1.9 GO:1900262 regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264)
0.2 4.6 GO:0043249 erythrocyte maturation(GO:0043249)
0.2 0.5 GO:1902523 positive regulation of protein K63-linked ubiquitination(GO:1902523)
0.2 2.7 GO:0000055 ribosomal large subunit export from nucleus(GO:0000055)
0.2 1.3 GO:0015886 heme transport(GO:0015886)
0.2 1.1 GO:0009597 detection of virus(GO:0009597)
0.2 0.9 GO:0015827 aromatic amino acid transport(GO:0015801) tryptophan transport(GO:0015827)
0.2 1.9 GO:0033314 mitotic DNA replication checkpoint(GO:0033314)
0.2 0.6 GO:1901420 negative regulation of vitamin D receptor signaling pathway(GO:0070563) negative regulation of response to alcohol(GO:1901420)
0.2 1.0 GO:1902340 telomeric heterochromatin assembly(GO:0031509) negative regulation of chromosome condensation(GO:1902340)
0.2 0.8 GO:0000390 spliceosomal complex disassembly(GO:0000390)
0.2 0.6 GO:1902202 regulation of hepatocyte growth factor receptor signaling pathway(GO:1902202)
0.2 0.6 GO:0070104 negative regulation of interleukin-6-mediated signaling pathway(GO:0070104)
0.2 0.4 GO:0000350 generation of catalytic spliceosome for second transesterification step(GO:0000350)
0.2 0.8 GO:0044208 'de novo' AMP biosynthetic process(GO:0044208)
0.2 1.2 GO:0006384 transcription initiation from RNA polymerase III promoter(GO:0006384)
0.2 0.8 GO:1904247 positive regulation of polynucleotide adenylyltransferase activity(GO:1904247)
0.2 1.3 GO:0019262 N-acetylneuraminate catabolic process(GO:0019262)
0.2 0.6 GO:0090526 regulation of gluconeogenesis involved in cellular glucose homeostasis(GO:0090526)
0.2 0.7 GO:2001188 negative regulation of immunological synapse formation(GO:2000521) regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell(GO:2001188) negative regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell(GO:2001189)
0.2 0.6 GO:0030961 peptidyl-arginine hydroxylation(GO:0030961)
0.2 0.9 GO:1903378 positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903378)
0.2 0.7 GO:0036233 glycine import(GO:0036233)
0.2 0.7 GO:0000056 ribosomal small subunit export from nucleus(GO:0000056)
0.2 1.2 GO:0042796 snRNA transcription from RNA polymerase III promoter(GO:0042796)
0.2 2.7 GO:0007213 G-protein coupled acetylcholine receptor signaling pathway(GO:0007213)
0.2 0.5 GO:0035771 interleukin-4-mediated signaling pathway(GO:0035771)
0.2 0.7 GO:0017055 negative regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0017055)
0.2 0.7 GO:0071348 cellular response to interleukin-11(GO:0071348)
0.2 3.3 GO:0006622 protein targeting to lysosome(GO:0006622)
0.2 4.8 GO:0032460 negative regulation of protein oligomerization(GO:0032460)
0.2 1.5 GO:0070561 vitamin D receptor signaling pathway(GO:0070561)
0.2 0.7 GO:0001560 regulation of cell growth by extracellular stimulus(GO:0001560)
0.2 2.3 GO:1904667 positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator(GO:1902255) negative regulation of ubiquitin protein ligase activity(GO:1904667)
0.2 2.9 GO:0000712 resolution of meiotic recombination intermediates(GO:0000712)
0.2 1.4 GO:2000659 regulation of interleukin-1-mediated signaling pathway(GO:2000659)
0.2 0.8 GO:0014886 transition between slow and fast fiber(GO:0014886)
0.2 0.5 GO:0046038 GMP catabolic process(GO:0046038) hypoxanthine metabolic process(GO:0046100) hypoxanthine biosynthetic process(GO:0046101)
0.2 0.5 GO:0015920 lipopolysaccharide transport(GO:0015920)
0.1 4.1 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.1 0.7 GO:0034154 toll-like receptor 7 signaling pathway(GO:0034154)
0.1 1.4 GO:0006335 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.1 0.4 GO:0006434 seryl-tRNA aminoacylation(GO:0006434)
0.1 0.6 GO:0000912 assembly of actomyosin apparatus involved in cytokinesis(GO:0000912) actomyosin contractile ring assembly(GO:0000915) actomyosin contractile ring organization(GO:0044837)
0.1 0.4 GO:0090673 endothelial cell-matrix adhesion(GO:0090673)
0.1 0.4 GO:1904172 positive regulation of bleb assembly(GO:1904172)
0.1 1.1 GO:0048539 bone marrow development(GO:0048539)
0.1 0.9 GO:2000774 positive regulation of cellular senescence(GO:2000774)
0.1 0.4 GO:0071460 cellular response to cell-matrix adhesion(GO:0071460)
0.1 0.5 GO:0001928 regulation of exocyst assembly(GO:0001928)
0.1 1.0 GO:0009644 response to high light intensity(GO:0009644)
0.1 0.6 GO:0036015 response to interleukin-3(GO:0036015) cellular response to interleukin-3(GO:0036016)
0.1 0.6 GO:0032055 negative regulation of translation in response to stress(GO:0032055)
0.1 1.4 GO:0031340 positive regulation of vesicle fusion(GO:0031340)
0.1 0.6 GO:0071475 cellular hyperosmotic salinity response(GO:0071475)
0.1 0.4 GO:0038018 Wnt receptor catabolic process(GO:0038018)
0.1 0.6 GO:1990743 protein sialylation(GO:1990743)
0.1 0.1 GO:0071029 polyadenylation-dependent ncRNA catabolic process(GO:0043634) nuclear ncRNA surveillance(GO:0071029) nuclear polyadenylation-dependent rRNA catabolic process(GO:0071035) nuclear polyadenylation-dependent ncRNA catabolic process(GO:0071046)
0.1 1.1 GO:0035878 nail development(GO:0035878)
0.1 0.4 GO:0010726 positive regulation of hydrogen peroxide metabolic process(GO:0010726)
0.1 0.4 GO:0048478 replication fork protection(GO:0048478)
0.1 2.9 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.1 0.3 GO:0070682 proteasome regulatory particle assembly(GO:0070682)
0.1 0.6 GO:2001166 regulation of histone H2B ubiquitination(GO:2001166) positive regulation of histone H2B ubiquitination(GO:2001168)
0.1 0.4 GO:0072365 regulation of cellular ketone metabolic process by negative regulation of transcription from RNA polymerase II promoter(GO:0072365)
0.1 5.4 GO:0016572 histone phosphorylation(GO:0016572)
0.1 0.4 GO:0016999 antibiotic metabolic process(GO:0016999)
0.1 2.3 GO:0016180 snRNA processing(GO:0016180)
0.1 1.9 GO:0070986 left/right axis specification(GO:0070986)
0.1 0.4 GO:0030450 regulation of complement activation, classical pathway(GO:0030450)
0.1 0.6 GO:0090070 positive regulation of ribosome biogenesis(GO:0090070) positive regulation of rRNA processing(GO:2000234)
0.1 0.5 GO:0034334 adherens junction maintenance(GO:0034334)
0.1 0.3 GO:0002879 positive regulation of acute inflammatory response to non-antigenic stimulus(GO:0002879)
0.1 0.6 GO:2000002 negative regulation of DNA damage checkpoint(GO:2000002)
0.1 1.1 GO:0048757 endosome to melanosome transport(GO:0035646) endosome to pigment granule transport(GO:0043485) pigment granule maturation(GO:0048757)
0.1 0.8 GO:0044027 hypermethylation of CpG island(GO:0044027)
0.1 1.8 GO:0075522 IRES-dependent viral translational initiation(GO:0075522)
0.1 0.2 GO:1905223 epicardium morphogenesis(GO:1905223)
0.1 0.2 GO:0060854 patterning of lymph vessels(GO:0060854)
0.1 1.8 GO:0051457 maintenance of protein location in nucleus(GO:0051457)
0.1 0.4 GO:0035054 embryonic heart tube anterior/posterior pattern specification(GO:0035054)
0.1 0.2 GO:0001180 transcription initiation from RNA polymerase I promoter for nuclear large rRNA transcript(GO:0001180)
0.1 0.3 GO:0090646 mitochondrial tRNA processing(GO:0090646)
0.1 0.8 GO:0045759 negative regulation of action potential(GO:0045759)
0.1 1.4 GO:0006337 nucleosome disassembly(GO:0006337)
0.1 0.4 GO:0034227 tRNA thio-modification(GO:0034227)
0.1 0.4 GO:1902416 positive regulation of mRNA binding(GO:1902416)
0.1 0.2 GO:0097694 establishment of RNA localization to telomere(GO:0097694)
0.1 1.3 GO:1990001 inhibition of cysteine-type endopeptidase activity involved in apoptotic process(GO:1990001)
0.1 1.6 GO:0034389 lipid particle organization(GO:0034389)
0.1 0.2 GO:2000587 negative regulation of platelet-derived growth factor receptor-beta signaling pathway(GO:2000587)
0.1 0.4 GO:0021764 amygdala development(GO:0021764)
0.1 0.1 GO:0002884 negative regulation of hypersensitivity(GO:0002884)
0.1 0.4 GO:0060744 thelarche(GO:0042695) mammary gland branching involved in thelarche(GO:0060744)
0.1 0.5 GO:1903003 positive regulation of protein deubiquitination(GO:1903003)
0.1 1.4 GO:0051531 NFAT protein import into nucleus(GO:0051531)
0.1 0.9 GO:1903504 regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090266) regulation of mitotic spindle checkpoint(GO:1903504)
0.1 0.5 GO:0007000 nucleolus organization(GO:0007000)
0.1 0.3 GO:0000963 mitochondrial RNA processing(GO:0000963)
0.1 0.5 GO:0044829 positive regulation by host of viral genome replication(GO:0044829)
0.1 0.5 GO:0046149 porphyrin-containing compound catabolic process(GO:0006787) tetrapyrrole catabolic process(GO:0033015) heme catabolic process(GO:0042167) pigment catabolic process(GO:0046149)
0.1 0.3 GO:0007084 mitotic nuclear envelope reassembly(GO:0007084)
0.1 1.3 GO:0007095 mitotic G2 DNA damage checkpoint(GO:0007095)
0.1 0.4 GO:0018002 N-terminal peptidyl-serine acetylation(GO:0017198) N-terminal peptidyl-glutamic acid acetylation(GO:0018002) peptidyl-serine acetylation(GO:0030920)
0.1 0.4 GO:0042424 catechol-containing compound catabolic process(GO:0019614) catecholamine catabolic process(GO:0042424)
0.1 0.2 GO:0051030 snRNA transport(GO:0051030)
0.1 1.1 GO:0009083 branched-chain amino acid catabolic process(GO:0009083)
0.1 3.0 GO:0070534 protein K63-linked ubiquitination(GO:0070534)
0.1 1.0 GO:0060352 cell adhesion molecule production(GO:0060352)
0.1 2.3 GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:0000184)
0.1 0.4 GO:0071883 activation of MAPK activity by adrenergic receptor signaling pathway(GO:0071883)
0.1 0.7 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.0 0.4 GO:0035021 negative regulation of Rac protein signal transduction(GO:0035021)
0.0 1.8 GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462)
0.0 0.6 GO:0044154 histone H3-K14 acetylation(GO:0044154)
0.0 3.8 GO:0048538 thymus development(GO:0048538)
0.0 0.2 GO:0072137 condensed mesenchymal cell proliferation(GO:0072137)
0.0 0.9 GO:1990403 embryonic brain development(GO:1990403)
0.0 0.3 GO:0019856 'de novo' pyrimidine nucleobase biosynthetic process(GO:0006207) pyrimidine nucleobase biosynthetic process(GO:0019856)
0.0 1.4 GO:0010592 positive regulation of lamellipodium assembly(GO:0010592)
0.0 0.8 GO:0010832 negative regulation of myotube differentiation(GO:0010832)
0.0 0.4 GO:0051771 negative regulation of nitric-oxide synthase biosynthetic process(GO:0051771)
0.0 0.3 GO:1990481 mRNA pseudouridine synthesis(GO:1990481)
0.0 0.3 GO:0006451 selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)
0.0 0.2 GO:0034552 respiratory chain complex II assembly(GO:0034552) mitochondrial respiratory chain complex II assembly(GO:0034553) mitochondrial respiratory chain complex II biogenesis(GO:0097032)
0.0 0.6 GO:0070933 histone H4 deacetylation(GO:0070933)
0.0 0.1 GO:0006546 glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464)
0.0 0.8 GO:0021942 radial glia guided migration of Purkinje cell(GO:0021942)
0.0 0.2 GO:0006420 arginyl-tRNA aminoacylation(GO:0006420)
0.0 0.4 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.0 0.4 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.0 0.4 GO:0035902 response to immobilization stress(GO:0035902)
0.0 0.2 GO:0050689 negative regulation of defense response to virus by host(GO:0050689)
0.0 1.3 GO:0031365 N-terminal protein amino acid modification(GO:0031365)
0.0 2.0 GO:1901224 positive regulation of NIK/NF-kappaB signaling(GO:1901224)
0.0 0.7 GO:1904814 regulation of protein localization to chromosome, telomeric region(GO:1904814) positive regulation of protein localization to chromosome, telomeric region(GO:1904816)
0.0 1.7 GO:0000132 establishment of mitotic spindle orientation(GO:0000132)
0.0 2.1 GO:0000266 mitochondrial fission(GO:0000266)
0.0 1.3 GO:0040015 negative regulation of multicellular organism growth(GO:0040015)
0.0 0.6 GO:1900242 regulation of synaptic vesicle endocytosis(GO:1900242)
0.0 0.5 GO:0030643 cellular phosphate ion homeostasis(GO:0030643) cellular trivalent inorganic anion homeostasis(GO:0072502)
0.0 0.2 GO:0061344 arterial endothelial cell fate commitment(GO:0060844) blood vessel endothelial cell fate commitment(GO:0060846) Notch signaling pathway involved in arterial endothelial cell fate commitment(GO:0060853) regulation of cell adhesion involved in heart morphogenesis(GO:0061344) blood vessel endothelial cell fate specification(GO:0097101) positive regulation of ephrin receptor signaling pathway(GO:1901189) positive regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901297) positive regulation of canonical Wnt signaling pathway involved in heart development(GO:1905068)
0.0 0.7 GO:0033623 regulation of integrin activation(GO:0033623)
0.0 0.3 GO:0001682 tRNA 5'-leader removal(GO:0001682)
0.0 0.3 GO:0002553 histamine production involved in inflammatory response(GO:0002349) histamine secretion involved in inflammatory response(GO:0002441) histamine secretion by mast cell(GO:0002553)
0.0 0.1 GO:0002501 MHC protein complex assembly(GO:0002396) peptide antigen assembly with MHC protein complex(GO:0002501)
0.0 0.6 GO:0071578 zinc II ion transmembrane import(GO:0071578)
0.0 1.2 GO:0034314 Arp2/3 complex-mediated actin nucleation(GO:0034314)
0.0 1.2 GO:0007080 mitotic metaphase plate congression(GO:0007080)
0.0 0.2 GO:0031161 phosphatidylinositol catabolic process(GO:0031161)
0.0 0.8 GO:0032967 positive regulation of collagen biosynthetic process(GO:0032967)
0.0 0.9 GO:0071353 cellular response to interleukin-4(GO:0071353)
0.0 4.2 GO:0043149 contractile actin filament bundle assembly(GO:0030038) stress fiber assembly(GO:0043149)
0.0 0.1 GO:1901874 negative regulation of cellular respiration(GO:1901856) regulation of post-translational protein modification(GO:1901873) negative regulation of post-translational protein modification(GO:1901874)
0.0 1.0 GO:1903427 negative regulation of reactive oxygen species biosynthetic process(GO:1903427)
0.0 0.2 GO:0033683 nucleotide-excision repair, DNA incision(GO:0033683)
0.0 0.2 GO:1904636 interleukin-21 production(GO:0032625) T follicular helper cell differentiation(GO:0061470) cellular response to ether(GO:0071362) interleukin-21 secretion(GO:0072619) response to ionomycin(GO:1904636) cellular response to ionomycin(GO:1904637)
0.0 1.5 GO:0043001 Golgi to plasma membrane protein transport(GO:0043001)
0.0 0.8 GO:0010569 regulation of double-strand break repair via homologous recombination(GO:0010569)
0.0 0.3 GO:0071763 nuclear membrane organization(GO:0071763)
0.0 0.4 GO:0032211 negative regulation of telomere maintenance via telomerase(GO:0032211)
0.0 0.2 GO:0051012 microtubule sliding(GO:0051012)
0.0 0.1 GO:0036228 protein targeting to nuclear inner membrane(GO:0036228)
0.0 0.1 GO:0072362 regulation of glycolytic process by negative regulation of transcription from RNA polymerase II promoter(GO:0072362)
0.0 0.2 GO:0006449 regulation of translational termination(GO:0006449)
0.0 0.3 GO:0010739 positive regulation of protein kinase A signaling(GO:0010739)
0.0 0.5 GO:0006613 cotranslational protein targeting to membrane(GO:0006613)
0.0 0.1 GO:0015811 L-cystine transport(GO:0015811)
0.0 0.4 GO:0060394 negative regulation of pathway-restricted SMAD protein phosphorylation(GO:0060394)
0.0 0.2 GO:2000051 negative regulation of non-canonical Wnt signaling pathway(GO:2000051)
0.0 0.4 GO:0016540 protein autoprocessing(GO:0016540)
0.0 0.2 GO:0009313 ganglioside catabolic process(GO:0006689) oligosaccharide catabolic process(GO:0009313)
0.0 0.3 GO:0030259 lipid glycosylation(GO:0030259)
0.0 0.1 GO:0042271 susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
0.0 0.1 GO:0070525 tRNA threonylcarbamoyladenosine metabolic process(GO:0070525)
0.0 1.2 GO:0016925 protein sumoylation(GO:0016925)
0.0 0.9 GO:0046839 phospholipid dephosphorylation(GO:0046839)
0.0 1.4 GO:0000245 spliceosomal complex assembly(GO:0000245)
0.0 0.3 GO:0000338 protein deneddylation(GO:0000338)
0.0 0.1 GO:0036462 TRAIL-activated apoptotic signaling pathway(GO:0036462)
0.0 0.7 GO:0015991 ATP hydrolysis coupled proton transport(GO:0015991)
0.0 0.1 GO:0006030 chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032)
0.0 0.8 GO:0010501 RNA secondary structure unwinding(GO:0010501)
0.0 0.4 GO:0003334 keratinocyte development(GO:0003334)
0.0 0.7 GO:0014003 oligodendrocyte development(GO:0014003)
0.0 0.1 GO:0033615 mitochondrial proton-transporting ATP synthase complex assembly(GO:0033615)
0.0 0.4 GO:0071539 protein localization to centrosome(GO:0071539)
0.0 0.3 GO:0032793 positive regulation of CREB transcription factor activity(GO:0032793)
0.0 1.2 GO:0070527 platelet aggregation(GO:0070527)
0.0 0.6 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.0 0.5 GO:0010800 positive regulation of peptidyl-threonine phosphorylation(GO:0010800)
0.0 0.2 GO:0070544 histone H3-K36 demethylation(GO:0070544)
0.0 1.1 GO:0031110 regulation of microtubule polymerization or depolymerization(GO:0031110)
0.0 0.0 GO:0006393 termination of mitochondrial transcription(GO:0006393)
0.0 2.6 GO:0008360 regulation of cell shape(GO:0008360)
0.0 0.4 GO:1990089 response to nerve growth factor(GO:1990089) cellular response to nerve growth factor stimulus(GO:1990090)
0.0 0.6 GO:0030512 negative regulation of transforming growth factor beta receptor signaling pathway(GO:0030512)
0.0 0.8 GO:0043124 negative regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043124)
0.0 0.1 GO:0016259 selenocysteine metabolic process(GO:0016259)
0.0 0.8 GO:0051225 spindle assembly(GO:0051225)
0.0 1.2 GO:0051965 positive regulation of synapse assembly(GO:0051965)
0.0 0.1 GO:0036337 Fas signaling pathway(GO:0036337)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
3.8 11.4 GO:0031904 endosome lumen(GO:0031904)
0.8 2.3 GO:0005668 RNA polymerase transcription factor SL1 complex(GO:0005668)
0.7 2.9 GO:0071821 FANCM-MHF complex(GO:0071821)
0.6 1.9 GO:0005760 gamma DNA polymerase complex(GO:0005760)
0.5 1.5 GO:1990879 CST complex(GO:1990879)
0.4 2.2 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.4 6.5 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.4 2.9 GO:0031095 platelet dense tubular network membrane(GO:0031095)
0.4 1.1 GO:0031372 UBC13-MMS2 complex(GO:0031372)
0.4 4.3 GO:0001940 male pronucleus(GO:0001940)
0.3 1.4 GO:1990578 perinuclear endoplasmic reticulum membrane(GO:1990578)
0.3 3.6 GO:0000808 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.3 1.2 GO:0014802 terminal cisterna(GO:0014802)
0.3 1.4 GO:0008622 epsilon DNA polymerase complex(GO:0008622)
0.3 0.8 GO:0038045 large latent transforming growth factor-beta complex(GO:0038045)
0.2 0.7 GO:0070992 translation initiation complex(GO:0070992)
0.2 1.2 GO:0031510 SUMO activating enzyme complex(GO:0031510)
0.2 1.4 GO:0070937 CRD-mediated mRNA stability complex(GO:0070937)
0.2 1.4 GO:1990393 3M complex(GO:1990393)
0.2 3.3 GO:0044754 autolysosome(GO:0044754)
0.2 0.6 GO:0005900 oncostatin-M receptor complex(GO:0005900)
0.2 1.9 GO:0031390 Ctf18 RFC-like complex(GO:0031390)
0.2 1.1 GO:0005947 mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947)
0.2 0.7 GO:0032021 NELF complex(GO:0032021)
0.2 2.4 GO:0043020 NADPH oxidase complex(GO:0043020)
0.2 0.8 GO:0031467 Cul7-RING ubiquitin ligase complex(GO:0031467) nuclear SCF ubiquitin ligase complex(GO:0043224)
0.2 2.5 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.2 1.7 GO:0034363 intermediate-density lipoprotein particle(GO:0034363)
0.2 5.1 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.1 0.6 GO:0033503 HULC complex(GO:0033503)
0.1 0.7 GO:0001939 female pronucleus(GO:0001939)
0.1 0.8 GO:0071008 U2-type post-mRNA release spliceosomal complex(GO:0071008)
0.1 0.6 GO:0035363 histone locus body(GO:0035363)
0.1 0.8 GO:0001674 female germ cell nucleus(GO:0001674)
0.1 3.8 GO:0001891 phagocytic cup(GO:0001891)
0.1 2.6 GO:0005652 nuclear lamina(GO:0005652)
0.1 0.8 GO:0030289 protein phosphatase 4 complex(GO:0030289)
0.1 0.8 GO:0072557 IPAF inflammasome complex(GO:0072557)
0.1 1.1 GO:0042575 DNA polymerase complex(GO:0042575)
0.1 2.5 GO:0031616 spindle pole centrosome(GO:0031616)
0.1 1.5 GO:0001527 microfibril(GO:0001527) fibril(GO:0043205)
0.1 0.2 GO:0044614 nuclear pore cytoplasmic filaments(GO:0044614)
0.1 3.1 GO:0000930 gamma-tubulin complex(GO:0000930)
0.1 1.9 GO:0032039 integrator complex(GO:0032039)
0.1 1.8 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.1 0.6 GO:0043564 Ku70:Ku80 complex(GO:0043564)
0.1 6.1 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.1 1.4 GO:0031209 SCAR complex(GO:0031209)
0.1 0.5 GO:0098560 cytoplasmic side of late endosome membrane(GO:0098560)
0.1 1.3 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.1 0.4 GO:0043541 UDP-N-acetylglucosamine transferase complex(GO:0043541)
0.1 0.6 GO:0097443 sorting endosome(GO:0097443)
0.1 1.9 GO:0005682 U5 snRNP(GO:0005682)
0.1 1.0 GO:0000788 nuclear nucleosome(GO:0000788)
0.1 0.6 GO:0042406 extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.1 2.4 GO:0005689 U12-type spliceosomal complex(GO:0005689)
0.1 0.7 GO:0005851 eukaryotic translation initiation factor 2B complex(GO:0005851)
0.1 2.1 GO:0005680 anaphase-promoting complex(GO:0005680)
0.1 0.4 GO:0032444 activin responsive factor complex(GO:0032444)
0.1 1.1 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.1 1.1 GO:0031080 nuclear pore outer ring(GO:0031080)
0.1 1.1 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.1 1.2 GO:0005641 nuclear envelope lumen(GO:0005641)
0.1 0.4 GO:0033553 rDNA heterochromatin(GO:0033553)
0.1 0.5 GO:0036195 muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195)
0.1 2.6 GO:0035145 exon-exon junction complex(GO:0035145)
0.1 0.9 GO:0000138 Golgi trans cisterna(GO:0000138)
0.1 0.6 GO:0000347 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.1 1.4 GO:0071564 npBAF complex(GO:0071564)
0.1 2.3 GO:0001741 XY body(GO:0001741)
0.1 0.5 GO:0070545 PeBoW complex(GO:0070545)
0.1 0.3 GO:0071014 post-mRNA release spliceosomal complex(GO:0071014)
0.1 0.6 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.1 2.4 GO:0097228 sperm principal piece(GO:0097228)
0.1 1.4 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.1 0.3 GO:0000938 GARP complex(GO:0000938) EARP complex(GO:1990745)
0.1 4.2 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.1 7.4 GO:0017053 transcriptional repressor complex(GO:0017053)
0.1 0.6 GO:0008024 cyclin/CDK positive transcription elongation factor complex(GO:0008024)
0.1 0.3 GO:0000172 ribonuclease MRP complex(GO:0000172)
0.1 1.1 GO:0033202 DNA helicase complex(GO:0033202)
0.1 0.5 GO:0070652 HAUS complex(GO:0070652)
0.0 0.5 GO:0042382 paraspeckles(GO:0042382)
0.0 4.2 GO:0005643 nuclear pore(GO:0005643)
0.0 0.6 GO:0030126 COPI vesicle coat(GO:0030126)
0.0 0.4 GO:0030485 smooth muscle contractile fiber(GO:0030485)
0.0 0.7 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.0 0.5 GO:0000974 Prp19 complex(GO:0000974)
0.0 0.6 GO:0090543 Flemming body(GO:0090543)
0.0 0.5 GO:0005688 U6 snRNP(GO:0005688)
0.0 0.6 GO:0031254 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.0 1.2 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.0 0.4 GO:0042405 nuclear inclusion body(GO:0042405)
0.0 0.3 GO:0030891 VCB complex(GO:0030891)
0.0 0.4 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.0 4.8 GO:0001725 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0 0.6 GO:0031143 pseudopodium(GO:0031143)
0.0 2.4 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 0.6 GO:0016342 catenin complex(GO:0016342)
0.0 0.4 GO:0032009 early phagosome(GO:0032009)
0.0 1.4 GO:0031941 filamentous actin(GO:0031941)
0.0 1.1 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.0 0.4 GO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
0.0 0.3 GO:0031415 NatA complex(GO:0031415)
0.0 0.3 GO:0042788 polysomal ribosome(GO:0042788)
0.0 3.7 GO:0000776 kinetochore(GO:0000776)
0.0 1.5 GO:0001772 immunological synapse(GO:0001772)
0.0 0.6 GO:0035253 ciliary rootlet(GO:0035253)
0.0 1.1 GO:0043596 nuclear replication fork(GO:0043596)
0.0 1.2 GO:0055038 recycling endosome membrane(GO:0055038)
0.0 1.3 GO:0032809 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.0 1.2 GO:0030684 preribosome(GO:0030684)
0.0 0.7 GO:0002102 podosome(GO:0002102)
0.0 0.3 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.0 0.0 GO:0072357 PTW/PP1 phosphatase complex(GO:0072357)
0.0 0.5 GO:0031528 microvillus membrane(GO:0031528)
0.0 0.1 GO:0031597 cytosolic proteasome complex(GO:0031597)
0.0 0.2 GO:0070187 telosome(GO:0070187)
0.0 2.4 GO:0016605 PML body(GO:0016605)
0.0 2.2 GO:0032587 ruffle membrane(GO:0032587)
0.0 0.7 GO:0042588 zymogen granule(GO:0042588)
0.0 1.6 GO:0036126 sperm flagellum(GO:0036126)
0.0 0.7 GO:0005637 nuclear inner membrane(GO:0005637)
0.0 4.2 GO:0031965 nuclear membrane(GO:0031965)
0.0 0.2 GO:0008540 proteasome regulatory particle, base subcomplex(GO:0008540)
0.0 5.7 GO:0000790 nuclear chromatin(GO:0000790)
0.0 0.4 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 0.1 GO:0000408 EKC/KEOPS complex(GO:0000408)
0.0 1.3 GO:0005884 actin filament(GO:0005884)
0.0 1.0 GO:0031985 Golgi cisterna(GO:0031985)
0.0 0.9 GO:0030119 AP-type membrane coat adaptor complex(GO:0030119)
0.0 1.1 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.0 0.7 GO:0042645 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.0 0.1 GO:0005610 laminin-5 complex(GO:0005610)
0.0 1.3 GO:0031234 extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
3.1 12.3 GO:0004566 beta-glucuronidase activity(GO:0004566)
0.6 1.9 GO:0016890 site-specific endodeoxyribonuclease activity, specific for altered base(GO:0016890)
0.5 10.9 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.5 3.4 GO:0055104 ligase inhibitor activity(GO:0055104) ubiquitin ligase inhibitor activity(GO:1990948)
0.5 1.4 GO:0045142 ATP-dependent DNA/RNA helicase activity(GO:0033680) triplex DNA binding(GO:0045142)
0.4 1.3 GO:0003858 3-hydroxybutyrate dehydrogenase activity(GO:0003858)
0.4 3.7 GO:0016936 galactoside binding(GO:0016936)
0.4 1.2 GO:0019948 SUMO activating enzyme activity(GO:0019948)
0.4 2.7 GO:0047179 platelet-activating factor acetyltransferase activity(GO:0047179)
0.4 2.1 GO:0004647 phosphoserine phosphatase activity(GO:0004647)
0.4 2.8 GO:0019158 fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.3 1.3 GO:0016833 oxo-acid-lyase activity(GO:0016833)
0.3 4.5 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.3 1.0 GO:0034188 apolipoprotein receptor activity(GO:0030226) apolipoprotein A-I receptor activity(GO:0034188) phosphatidylserine-translocating ATPase activity(GO:0090556)
0.3 1.8 GO:0004852 uroporphyrinogen-III synthase activity(GO:0004852)
0.2 0.7 GO:0050785 advanced glycation end-product receptor activity(GO:0050785)
0.2 3.6 GO:0003688 DNA replication origin binding(GO:0003688)
0.2 1.3 GO:0015232 heme transporter activity(GO:0015232)
0.2 0.9 GO:0070180 large ribosomal subunit rRNA binding(GO:0070180)
0.2 0.6 GO:0004915 interleukin-6 receptor activity(GO:0004915) interleukin-6 binding(GO:0019981)
0.2 0.8 GO:0050436 microfibril binding(GO:0050436)
0.2 0.8 GO:0016842 amidine-lyase activity(GO:0016842)
0.2 0.6 GO:0016262 protein N-acetylglucosaminyltransferase activity(GO:0016262)
0.2 0.8 GO:0004949 cannabinoid receptor activity(GO:0004949)
0.2 0.6 GO:0031871 proteinase activated receptor binding(GO:0031871)
0.2 2.4 GO:0016175 superoxide-generating NADPH oxidase activity(GO:0016175)
0.2 0.7 GO:1990932 5.8S rRNA binding(GO:1990932)
0.2 1.9 GO:0003689 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.2 0.7 GO:0002153 steroid receptor RNA activator RNA binding(GO:0002153)
0.2 1.4 GO:0043125 ErbB-3 class receptor binding(GO:0043125)
0.2 0.5 GO:0017116 single-stranded DNA-dependent ATP-dependent DNA helicase activity(GO:0017116)
0.2 1.5 GO:0004032 alditol:NADP+ 1-oxidoreductase activity(GO:0004032)
0.2 0.9 GO:0047493 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.2 6.5 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.1 1.0 GO:0019808 polyamine binding(GO:0019808)
0.1 1.3 GO:0019960 C-X3-C chemokine binding(GO:0019960)
0.1 1.9 GO:0017169 CDP-alcohol phosphatidyltransferase activity(GO:0017169)
0.1 0.4 GO:0016206 catechol O-methyltransferase activity(GO:0016206)
0.1 0.9 GO:0008241 peptidyl-dipeptidase activity(GO:0008241)
0.1 1.7 GO:0016004 phospholipase activator activity(GO:0016004)
0.1 0.4 GO:0004828 serine-tRNA ligase activity(GO:0004828)
0.1 7.1 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.1 1.4 GO:0008310 single-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008310)
0.1 0.5 GO:0047389 glycerophosphocholine phosphodiesterase activity(GO:0047389)
0.1 0.4 GO:0000386 second spliceosomal transesterification activity(GO:0000386)
0.1 0.5 GO:0005136 interleukin-4 receptor binding(GO:0005136)
0.1 1.8 GO:1990829 C-rich single-stranded DNA binding(GO:1990829)
0.1 1.8 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.1 0.6 GO:0034211 GTP-dependent protein kinase activity(GO:0034211)
0.1 3.0 GO:0051010 microtubule plus-end binding(GO:0051010)
0.1 0.6 GO:0004074 biliverdin reductase activity(GO:0004074)
0.1 4.7 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.1 0.4 GO:0050508 glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.1 0.6 GO:0003829 beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0003829)
0.1 1.1 GO:0097642 calcitonin family receptor activity(GO:0097642)
0.1 0.4 GO:0052594 tryptamine:oxygen oxidoreductase (deaminating) activity(GO:0052593) aminoacetone:oxygen oxidoreductase(deaminating) activity(GO:0052594) aliphatic-amine oxidase activity(GO:0052595) phenethylamine:oxygen oxidoreductase (deaminating) activity(GO:0052596)
0.1 2.2 GO:0098748 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.1 12.3 GO:0004869 cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.1 0.5 GO:0070506 high-density lipoprotein particle receptor activity(GO:0070506)
0.1 0.8 GO:0004704 NF-kappaB-inducing kinase activity(GO:0004704)
0.1 3.1 GO:0032794 GTPase activating protein binding(GO:0032794)
0.1 1.7 GO:0043047 single-stranded telomeric DNA binding(GO:0043047)
0.1 0.6 GO:0004826 phenylalanine-tRNA ligase activity(GO:0004826)
0.1 0.3 GO:0016426 tRNA (adenine) methyltransferase activity(GO:0016426)
0.1 1.2 GO:0016494 C-X-C chemokine receptor activity(GO:0016494)
0.1 1.3 GO:0001054 RNA polymerase I activity(GO:0001054)
0.1 1.0 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.1 0.6 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.1 1.7 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.1 4.4 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.1 2.4 GO:0042162 telomeric DNA binding(GO:0042162)
0.1 4.3 GO:0097472 cyclin-dependent protein kinase activity(GO:0097472)
0.1 3.3 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.1 0.6 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.1 1.9 GO:0043274 phospholipase binding(GO:0043274)
0.1 0.5 GO:0034618 arginine binding(GO:0034618)
0.1 0.8 GO:0019788 NEDD8 transferase activity(GO:0019788)
0.1 0.8 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.1 2.1 GO:0004190 aspartic-type endopeptidase activity(GO:0004190)
0.1 0.8 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.1 0.6 GO:0032453 histone demethylase activity (H3-K4 specific)(GO:0032453)
0.1 2.7 GO:0031683 G-protein beta/gamma-subunit complex binding(GO:0031683)
0.1 0.3 GO:0016635 oxidoreductase activity, acting on the CH-CH group of donors, quinone or related compound as acceptor(GO:0016635)
0.1 0.3 GO:0035368 selenocysteine insertion sequence binding(GO:0035368)
0.1 0.2 GO:0070336 flap-structured DNA binding(GO:0070336)
0.1 0.6 GO:0005131 growth hormone receptor binding(GO:0005131)
0.1 2.2 GO:0043236 laminin binding(GO:0043236)
0.1 0.7 GO:0008097 5S rRNA binding(GO:0008097)
0.1 0.4 GO:0070004 cysteine-type carboxypeptidase activity(GO:0016807) cysteine-type exopeptidase activity(GO:0070004)
0.1 0.7 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.1 0.5 GO:0042731 PH domain binding(GO:0042731)
0.1 0.5 GO:1990247 N6-methyladenosine-containing RNA binding(GO:1990247)
0.1 0.8 GO:0042577 lipid phosphatase activity(GO:0042577)
0.1 0.4 GO:1990190 peptide-glutamate-N-acetyltransferase activity(GO:1990190)
0.1 1.2 GO:0004679 AMP-activated protein kinase activity(GO:0004679)
0.1 0.5 GO:0050897 cobalt ion binding(GO:0050897)
0.1 0.7 GO:0015187 glycine transmembrane transporter activity(GO:0015187)
0.1 0.4 GO:0004931 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.1 0.2 GO:0000822 inositol hexakisphosphate binding(GO:0000822)
0.0 0.5 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.0 0.1 GO:0001156 TFIIIC-class transcription factor binding(GO:0001156)
0.0 0.4 GO:0045504 dynein heavy chain binding(GO:0045504)
0.0 1.4 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 0.3 GO:0097157 pre-mRNA intronic binding(GO:0097157)
0.0 0.9 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.0 0.6 GO:0045294 alpha-catenin binding(GO:0045294)
0.0 0.1 GO:0042015 interleukin-20 binding(GO:0042015)
0.0 0.6 GO:0015093 ferrous iron transmembrane transporter activity(GO:0015093)
0.0 1.0 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 1.7 GO:0070717 poly-purine tract binding(GO:0070717)
0.0 0.9 GO:0001618 virus receptor activity(GO:0001618)
0.0 0.2 GO:0004661 protein geranylgeranyltransferase activity(GO:0004661)
0.0 0.3 GO:0008440 inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440)
0.0 0.5 GO:0015194 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.0 7.0 GO:0003735 structural constituent of ribosome(GO:0003735)
0.0 3.2 GO:0030507 spectrin binding(GO:0030507)
0.0 0.4 GO:0036310 annealing helicase activity(GO:0036310)
0.0 0.4 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.0 0.1 GO:0097199 cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097199)
0.0 4.7 GO:0033613 activating transcription factor binding(GO:0033613)
0.0 1.8 GO:0016504 peptidase activator activity(GO:0016504)
0.0 0.3 GO:0008494 translation activator activity(GO:0008494)
0.0 3.1 GO:0002039 p53 binding(GO:0002039)
0.0 0.2 GO:0052795 exo-alpha-sialidase activity(GO:0004308) alpha-sialidase activity(GO:0016997) exo-alpha-(2->3)-sialidase activity(GO:0052794) exo-alpha-(2->6)-sialidase activity(GO:0052795) exo-alpha-(2->8)-sialidase activity(GO:0052796)
0.0 0.3 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609)
0.0 3.9 GO:0042562 hormone binding(GO:0042562)
0.0 1.5 GO:0051879 Hsp90 protein binding(GO:0051879)
0.0 1.1 GO:0019843 rRNA binding(GO:0019843)
0.0 0.9 GO:0017160 Ral GTPase binding(GO:0017160)
0.0 0.7 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0 1.9 GO:0043022 ribosome binding(GO:0043022)
0.0 2.1 GO:0003724 RNA helicase activity(GO:0003724) ATP-dependent RNA helicase activity(GO:0004004) RNA-dependent ATPase activity(GO:0008186)
0.0 0.3 GO:0043024 ribosomal small subunit binding(GO:0043024)
0.0 0.3 GO:0004526 ribonuclease P activity(GO:0004526)
0.0 0.2 GO:0052833 inositol monophosphate 1-phosphatase activity(GO:0008934) inositol monophosphate 3-phosphatase activity(GO:0052832) inositol monophosphate 4-phosphatase activity(GO:0052833) inositol monophosphate phosphatase activity(GO:0052834)
0.0 0.1 GO:0030171 voltage-gated proton channel activity(GO:0030171)
0.0 0.7 GO:0035325 Toll-like receptor binding(GO:0035325)
0.0 1.2 GO:0015036 disulfide oxidoreductase activity(GO:0015036)
0.0 0.3 GO:0001056 RNA polymerase III activity(GO:0001056)
0.0 4.2 GO:0002020 protease binding(GO:0002020)
0.0 2.0 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 1.0 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.0 1.4 GO:0043548 phosphatidylinositol 3-kinase binding(GO:0043548)
0.0 0.5 GO:0004551 nucleotide diphosphatase activity(GO:0004551)
0.0 0.7 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.0 0.4 GO:0070410 co-SMAD binding(GO:0070410)
0.0 0.9 GO:0051721 protein phosphatase 2A binding(GO:0051721)
0.0 1.7 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.0 0.4 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.0 0.4 GO:0001968 fibronectin binding(GO:0001968)
0.0 0.3 GO:0008179 adenylate cyclase binding(GO:0008179)
0.0 0.2 GO:0070411 transforming growth factor beta receptor activity, type I(GO:0005025) I-SMAD binding(GO:0070411)
0.0 2.4 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 0.5 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.0 1.1 GO:0004177 aminopeptidase activity(GO:0004177)
0.0 0.1 GO:0033797 selenate reductase activity(GO:0033797) mercury ion binding(GO:0045340)
0.0 0.9 GO:0004364 glutathione transferase activity(GO:0004364)
0.0 0.1 GO:0015184 L-cystine transmembrane transporter activity(GO:0015184)
0.0 0.2 GO:0032183 SUMO binding(GO:0032183)
0.0 0.1 GO:0004568 chitinase activity(GO:0004568)
0.0 0.2 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0 0.7 GO:0003743 translation initiation factor activity(GO:0003743)
0.0 0.3 GO:0005521 lamin binding(GO:0005521)
0.0 1.4 GO:0032947 protein complex scaffold(GO:0032947)
0.0 0.3 GO:0017049 GTP-Rho binding(GO:0017049)
0.0 0.2 GO:0001134 transcription factor activity, transcription factor recruiting(GO:0001134)
0.0 0.2 GO:0015643 toxic substance binding(GO:0015643)
0.0 0.5 GO:0003785 actin monomer binding(GO:0003785)
0.0 4.4 GO:0045296 cadherin binding(GO:0045296)
0.0 0.2 GO:0046703 natural killer cell lectin-like receptor binding(GO:0046703)
0.0 0.7 GO:0031593 polyubiquitin binding(GO:0031593)
0.0 0.3 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.0 0.4 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 4.3 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.2 13.3 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.2 3.6 PID S1P S1P4 PATHWAY S1P4 pathway
0.2 4.1 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.1 7.7 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.1 7.0 PID ATR PATHWAY ATR signaling pathway
0.1 6.5 PID BMP PATHWAY BMP receptor signaling
0.1 4.3 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.1 4.7 PID AURORA A PATHWAY Aurora A signaling
0.1 3.8 PID FOXM1 PATHWAY FOXM1 transcription factor network
0.1 3.6 PID IL27 PATHWAY IL27-mediated signaling events
0.1 2.7 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.1 4.5 PID RAC1 PATHWAY RAC1 signaling pathway
0.1 1.2 PID IL5 PATHWAY IL5-mediated signaling events
0.1 1.3 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.0 1.8 ST TUMOR NECROSIS FACTOR PATHWAY Tumor Necrosis Factor Pathway.
0.0 2.8 PID P53 REGULATION PATHWAY p53 pathway
0.0 2.8 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.0 2.3 PID TGFBR PATHWAY TGF-beta receptor signaling
0.0 3.6 PID AR PATHWAY Coregulation of Androgen receptor activity
0.0 0.4 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.0 1.6 PID LKB1 PATHWAY LKB1 signaling events
0.0 0.6 ST GA13 PATHWAY G alpha 13 Pathway
0.0 0.6 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.0 1.2 SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES Genes related to the insulin receptor pathway
0.0 0.9 PID IL2 PI3K PATHWAY IL2 signaling events mediated by PI3K
0.0 1.3 PID HEDGEHOG GLI PATHWAY Hedgehog signaling events mediated by Gli proteins
0.0 1.9 ST INTEGRIN SIGNALING PATHWAY Integrin Signaling Pathway
0.0 0.3 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0 0.6 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.0 0.4 ST PHOSPHOINOSITIDE 3 KINASE PATHWAY PI3K Pathway
0.0 1.1 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 0.6 PID THROMBIN PAR1 PATHWAY PAR1-mediated thrombin signaling events
0.0 0.8 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.0 0.9 PID REG GR PATHWAY Glucocorticoid receptor regulatory network
0.0 0.5 PID INTEGRIN3 PATHWAY Beta3 integrin cell surface interactions
0.0 0.4 PID CDC42 PATHWAY CDC42 signaling events
0.0 0.4 PID TELOMERASE PATHWAY Regulation of Telomerase
0.0 0.4 PID PI3KCI PATHWAY Class I PI3K signaling events
0.0 0.3 PID NETRIN PATHWAY Netrin-mediated signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 8.1 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.3 0.9 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.2 7.5 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.2 3.6 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.2 1.5 REACTOME REPAIR SYNTHESIS FOR GAP FILLING BY DNA POL IN TC NER Genes involved in Repair synthesis for gap-filling by DNA polymerase in TC-NER
0.2 6.7 REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
0.1 1.9 REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
0.1 2.7 REACTOME ADENYLATE CYCLASE INHIBITORY PATHWAY Genes involved in Adenylate cyclase inhibitory pathway
0.1 2.2 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.1 13.3 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.1 2.2 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.1 3.2 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.1 1.9 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.1 2.2 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.1 1.7 REACTOME RNA POL I TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase I Transcription Termination
0.1 1.6 REACTOME REGULATION OF AMPK ACTIVITY VIA LKB1 Genes involved in Regulation of AMPK activity via LKB1
0.1 1.0 REACTOME RNA POL I PROMOTER OPENING Genes involved in RNA Polymerase I Promoter Opening
0.1 11.0 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.1 9.1 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.1 1.7 REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
0.1 4.5 REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES Genes involved in Antiviral mechanism by IFN-stimulated genes
0.1 1.1 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.1 2.4 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.1 2.1 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.1 1.2 REACTOME PHOSPHORYLATION OF THE APC C Genes involved in Phosphorylation of the APC/C
0.1 2.9 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport
0.1 3.1 REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.1 9.7 REACTOME MRNA SPLICING Genes involved in mRNA Splicing
0.1 0.6 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
0.1 2.9 REACTOME GLUCOSE TRANSPORT Genes involved in Glucose transport
0.1 1.9 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
0.1 0.7 REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR Genes involved in Trafficking and processing of endosomal TLR
0.0 2.5 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0 0.6 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.0 1.6 REACTOME SRP DEPENDENT COTRANSLATIONAL PROTEIN TARGETING TO MEMBRANE Genes involved in SRP-dependent cotranslational protein targeting to membrane
0.0 0.8 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0 0.6 REACTOME INTEGRATION OF PROVIRUS Genes involved in Integration of provirus
0.0 0.6 REACTOME REGULATION OF IFNG SIGNALING Genes involved in Regulation of IFNG signaling
0.0 0.3 REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.0 0.8 REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 3 PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter
0.0 0.4 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.0 1.2 REACTOME NOD1 2 SIGNALING PATHWAY Genes involved in NOD1/2 Signaling Pathway
0.0 0.4 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.0 2.2 REACTOME EXTRACELLULAR MATRIX ORGANIZATION Genes involved in Extracellular matrix organization
0.0 0.2 REACTOME PACKAGING OF TELOMERE ENDS Genes involved in Packaging Of Telomere Ends
0.0 1.0 REACTOME SYNTHESIS OF PC Genes involved in Synthesis of PC
0.0 0.5 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.0 0.5 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0 1.1 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 0.4 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.0 1.0 REACTOME TRANSLATION Genes involved in Translation
0.0 0.3 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.0 0.6 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.0 0.6 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0 0.3 REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.0 0.5 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.0 3.8 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.0 0.2 REACTOME FORMATION OF RNA POL II ELONGATION COMPLEX Genes involved in Formation of RNA Pol II elongation complex
0.0 0.2 REACTOME KERATAN SULFATE BIOSYNTHESIS Genes involved in Keratan sulfate biosynthesis
0.0 0.8 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 0.5 REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0 0.9 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 0.7 REACTOME INTERFERON GAMMA SIGNALING Genes involved in Interferon gamma signaling
0.0 0.3 REACTOME NUCLEOTIDE LIKE PURINERGIC RECEPTORS Genes involved in Nucleotide-like (purinergic) receptors
0.0 0.5 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.0 0.2 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.0 0.4 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression