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GSE58827: Dynamics of the Mouse Liver

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Results for Pou2f2_Pou3f1

Z-value: 1.59

Motif logo

Transcription factors associated with Pou2f2_Pou3f1

Gene Symbol Gene ID Gene Info
ENSMUSG00000008496.20 POU domain, class 2, transcription factor 2
ENSMUSG00000090125.4 POU domain, class 3, transcription factor 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Pou2f2mm39_v1_chr7_-_24831892_248319370.538.5e-04Click!
Pou3f1mm39_v1_chr4_+_124550600_124550600-0.173.2e-01Click!

Activity profile of Pou2f2_Pou3f1 motif

Sorted Z-values of Pou2f2_Pou3f1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr6_-_67014383 13.29 ENSMUST00000043098.9
growth arrest and DNA-damage-inducible 45 alpha
chr11_-_69496655 12.78 ENSMUST00000047889.13
ATPase, Na+/K+ transporting, beta 2 polypeptide
chr11_+_95227836 10.54 ENSMUST00000037502.7
family with sequence similarity 117, member A
chr7_-_4815542 10.48 ENSMUST00000079496.9
ubiquitin-conjugating enzyme E2S
chr12_-_36092475 8.22 ENSMUST00000020896.17
tetraspanin 13
chr15_-_66703471 8.12 ENSMUST00000164163.8
src-like adaptor
chr11_+_58839716 7.76 ENSMUST00000078267.5
H2B.U histone 2
chr6_-_67014348 7.63 ENSMUST00000204369.2
growth arrest and DNA-damage-inducible 45 alpha
chr10_+_75784126 7.48 ENSMUST00000000926.3
pre-B lymphocyte gene 3
chr8_+_23464860 7.24 ENSMUST00000110688.9
ENSMUST00000121802.9
ankyrin 1, erythroid
chr6_-_68713748 7.11 ENSMUST00000183936.2
ENSMUST00000196863.2
immunoglobulin kappa chain variable 19-93
chr1_+_91468409 7.00 ENSMUST00000027538.9
ENSMUST00000190484.7
ENSMUST00000186068.2
ankyrin repeat and SOCS box-containing 1
chr6_+_145091196 6.79 ENSMUST00000156849.8
ENSMUST00000132948.2
lymphoid-restricted membrane protein
chr17_+_29709723 6.74 ENSMUST00000024811.9
proviral integration site 1
chr3_+_51568588 6.57 ENSMUST00000099106.10
microsomal glutathione S-transferase 2
chr6_-_67014191 6.40 ENSMUST00000204282.2
growth arrest and DNA-damage-inducible 45 alpha
chr13_+_23930717 6.23 ENSMUST00000099703.5
H2B clustered histone 3
chrX_+_92718695 6.09 ENSMUST00000045898.4
phosphate cytidylyltransferase 1, choline, beta isoform
chr11_-_106205320 5.82 ENSMUST00000167143.2
CD79B antigen
chrX_+_55500170 5.54 ENSMUST00000039374.9
ENSMUST00000101553.9
ENSMUST00000186445.7
integrator complex subunit 6 like
chr13_-_22227114 5.44 ENSMUST00000091741.6
H2A clustered histone 11
chr17_+_27775637 5.27 ENSMUST00000117254.9
ENSMUST00000231243.2
ENSMUST00000231358.2
ENSMUST00000118570.2
ENSMUST00000231796.2
high mobility group AT-hook 1
chr5_+_137627431 5.25 ENSMUST00000176667.8
leucine-rich repeats and calponin homology (CH) domain containing 4
chr17_+_27775613 5.24 ENSMUST00000231780.2
ENSMUST00000232253.2
ENSMUST00000232552.2
ENSMUST00000117600.9
high mobility group AT-hook 1
chr17_+_27775471 5.17 ENSMUST00000118599.9
ENSMUST00000232265.2
ENSMUST00000232013.2
ENSMUST00000114888.11
ENSMUST00000231874.2
ENSMUST00000119486.9
ENSMUST00000231825.2
ENSMUST00000231866.2
high mobility group AT-hook 1
chr13_+_22227359 4.86 ENSMUST00000110452.2
H2B clustered histone 11
chr7_+_126376099 4.76 ENSMUST00000038614.12
ENSMUST00000170882.8
ENSMUST00000106359.2
ENSMUST00000106357.8
ENSMUST00000145762.8
yippee like 3
chr5_+_137628377 4.68 ENSMUST00000175968.8
leucine-rich repeats and calponin homology (CH) domain containing 4
chr12_-_113542610 4.66 ENSMUST00000195468.6
ENSMUST00000103442.3
immunoglobulin heavy variable 5-2
chr1_+_91468266 4.52 ENSMUST00000086843.11
ankyrin repeat and SOCS box-containing 1
chr14_-_67953035 4.52 ENSMUST00000163100.8
ENSMUST00000132705.8
ENSMUST00000124045.3
cell division cycle associated 2
chr4_-_152561896 4.51 ENSMUST00000238738.2
ENSMUST00000162017.3
ENSMUST00000030768.10
potassium voltage-gated channel, shaker-related subfamily, beta member 2
chr12_-_113823290 4.51 ENSMUST00000103459.5
immunoglobulin heavy variable 5-17
chr11_+_58845502 4.44 ENSMUST00000108817.5
ENSMUST00000047697.12
H2A.W histone
tripartite motif-containing 17
chr4_+_152123772 4.42 ENSMUST00000084116.13
ENSMUST00000103197.5
nucleolar protein 9
chrX_-_165992311 4.38 ENSMUST00000112172.4
thymosin, beta 4, X chromosome
chr12_-_113561594 4.36 ENSMUST00000103444.3
immunoglobulin heavy variable 5-4
chrX_-_165992145 4.35 ENSMUST00000112176.8
thymosin, beta 4, X chromosome
chr10_-_88520877 4.21 ENSMUST00000138734.2
Spi-C transcription factor (Spi-1/PU.1 related)
chr12_-_113589576 4.16 ENSMUST00000103446.2
immunoglobulin heavy variable 5-6
chr6_-_56878854 3.99 ENSMUST00000101367.9
5'-nucleotidase, cytosolic III
chr12_-_114443071 3.92 ENSMUST00000103492.2
immunoglobulin heavy variable 10-1
chr7_+_126376353 3.92 ENSMUST00000106356.2
yippee like 3
chr13_-_23755374 3.75 ENSMUST00000102969.6
H2A clustered histone 8
chr19_-_46033353 3.73 ENSMUST00000026252.14
ENSMUST00000156585.9
ENSMUST00000185355.7
ENSMUST00000152946.8
LIM domain binding 1
chr12_-_113802603 3.71 ENSMUST00000103458.3
ENSMUST00000193652.2
immunoglobulin heavy variable 5-16
chr13_+_21906214 3.68 ENSMUST00000224651.2
H2B clustered histone 14
chr19_+_8919228 3.64 ENSMUST00000096240.3
metastasis-associated gene family, member 2
chr13_-_22017677 3.60 ENSMUST00000081342.7
H2A clustered histone 24
chr7_-_143014726 3.57 ENSMUST00000167912.9
ENSMUST00000037287.8
cyclin-dependent kinase inhibitor 1C (P57)
chr6_-_69800923 3.56 ENSMUST00000103368.3
immunoglobulin kappa chain variable 5-43
chr3_+_96177010 3.47 ENSMUST00000051089.4
ENSMUST00000177113.2
predicted gene 42743
H2B clustered histone 18
chr6_+_67586695 3.46 ENSMUST00000103303.3
immunoglobulin kappa variable 1-135
chr13_+_23935088 3.39 ENSMUST00000078369.3
H2A clustered histone 4
chr17_-_35383867 3.30 ENSMUST00000025253.12
proline-rich coiled-coil 2A
chr7_+_44667377 3.25 ENSMUST00000044111.10
related RAS viral (r-ras) oncogene
chr2_-_152239966 3.18 ENSMUST00000063332.9
ENSMUST00000182625.2
SRY (sex determining region Y)-box 12
chr11_-_5787743 3.18 ENSMUST00000109837.8
polymerase (DNA directed), mu
chr12_-_113666198 3.16 ENSMUST00000103450.4
immunoglobulin heavy variable 5-12
chr12_-_113860566 3.14 ENSMUST00000103474.5
immunoglobulin heavy variable 7-1
chr2_+_160487801 3.01 ENSMUST00000109468.3
topoisomerase (DNA) I
chr12_-_114752425 2.99 ENSMUST00000103510.2
immunoglobulin heavy variable 1-26
chr16_+_91526169 2.98 ENSMUST00000114001.8
ENSMUST00000113999.8
ENSMUST00000064797.12
ENSMUST00000114002.9
ENSMUST00000095909.10
ENSMUST00000056482.14
ENSMUST00000113996.8
intersectin 1 (SH3 domain protein 1A)
chr6_-_68609426 2.98 ENSMUST00000103328.3
immunoglobulin kappa variable 10-96
chr10_+_79762858 2.87 ENSMUST00000019708.12
ENSMUST00000105377.8
AT rich interactive domain 3A (BRIGHT-like)
chr13_+_21994588 2.81 ENSMUST00000091745.6
H2A clustered histone 23
chr12_-_114355789 2.81 ENSMUST00000103486.2
immunoglobulin heavy variable 6-3
chr7_-_44180700 2.75 ENSMUST00000205506.2
Spi-B transcription factor (Spi-1/PU.1 related)
chr14_+_26722319 2.74 ENSMUST00000035433.10
homeobox gene expressed in ES cells
chr9_+_71123061 2.71 ENSMUST00000034723.6
aldehyde dehydrogenase family 1, subfamily A2
chr2_+_25070749 2.68 ENSMUST00000104999.4
Notch-regulated ankyrin repeat protein
chr6_+_68247469 2.63 ENSMUST00000103321.3
immunoglobulin kappa variable 1-110
chr10_-_80257681 2.62 ENSMUST00000156244.2
transcription factor 3
chr13_+_22220000 2.57 ENSMUST00000110455.4
H2B clustered histone 12
chr12_-_114487525 2.56 ENSMUST00000103495.3
immunoglobulin heavy variable V10-3
chr8_+_71151581 2.55 ENSMUST00000095267.8
jun D proto-oncogene
chr4_-_128699838 2.52 ENSMUST00000106072.9
ENSMUST00000170934.3
zinc finger protein 362
chr12_-_114321838 2.44 ENSMUST00000125484.3
immunoglobulin heavy variable 13-2
chr8_-_65489834 2.42 ENSMUST00000142822.4
apelin receptor early endogenous ligand
chr6_+_68279392 2.39 ENSMUST00000103322.3
immunoglobulin kappa variable 2-109
chr8_+_121215155 2.37 ENSMUST00000034279.16
genetic suppressor element 1, coiled-coil protein
chr9_-_22300409 2.33 ENSMUST00000040912.9
anillin, actin binding protein
chr6_-_69741999 2.33 ENSMUST00000103365.3
immunoglobulin kappa variable 12-46
chr19_+_47217279 2.31 ENSMUST00000111807.5
neuralized E3 ubiquitin protein ligase 1A
chr12_-_113912416 2.29 ENSMUST00000103464.3
immunoglobulin heavy variable 4-1
chr11_+_98632631 2.28 ENSMUST00000064187.12
thyroid hormone receptor alpha
chr2_+_90927053 2.27 ENSMUST00000132741.3
spleen focus forming virus (SFFV) proviral integration oncogene
chr12_-_113790741 2.27 ENSMUST00000103457.3
ENSMUST00000192877.2
immunoglobulin heavy variable 5-15
chr2_-_152672535 2.26 ENSMUST00000146380.2
ENSMUST00000134902.2
ENSMUST00000134357.2
ENSMUST00000109820.5
BCL2-like 1
chr8_+_71069476 2.25 ENSMUST00000052437.6
leucine rich repeat containing 25
chr6_+_68026941 2.23 ENSMUST00000103316.2
immunoglobulin kappa chain variable 9-120
chr6_+_136495784 2.20 ENSMUST00000032335.13
ENSMUST00000185724.7
activating transcription factor 7 interacting protein
chr2_-_102282844 2.20 ENSMUST00000099678.5
four jointed box 1
chrX_+_132751729 2.19 ENSMUST00000033602.9
tenomodulin
chr8_-_123187406 2.00 ENSMUST00000006762.7
snail family zinc finger 3
chr7_+_24981604 1.99 ENSMUST00000163320.8
ENSMUST00000005578.13
capicua transcriptional repressor
chr2_-_152672185 1.98 ENSMUST00000140436.2
BCL2-like 1
chr7_+_127345909 1.94 ENSMUST00000033081.14
F-box and leucine-rich repeat protein 19
chr12_-_113700190 1.94 ENSMUST00000103452.3
ENSMUST00000192264.2
immunoglobulin heavy variable 5-9-1
chr7_+_27186335 1.92 ENSMUST00000008528.8
SERTA domain containing 1
chr6_+_68098030 1.91 ENSMUST00000103317.3
immunoglobulin kappa variable 1-117
chr12_-_114502585 1.86 ENSMUST00000103496.4
immunoglobulin heavy variable V1-7
chr12_-_114226570 1.85 ENSMUST00000103479.4
ENSMUST00000195619.2
immunoglobulin heavy variable 3-5
chr7_+_121888520 1.85 ENSMUST00000064989.12
ENSMUST00000064921.5
protein kinase C, beta
chr6_-_69792108 1.83 ENSMUST00000103367.3
immunoglobulin kappa variable 12-44
chr4_-_63965161 1.81 ENSMUST00000107377.10
tenascin C
chr8_-_65489791 1.79 ENSMUST00000124790.8
apelin receptor early endogenous ligand
chr13_+_83723255 1.76 ENSMUST00000199167.5
ENSMUST00000195904.5
myocyte enhancer factor 2C
chr7_+_24206431 1.72 ENSMUST00000176880.2
zinc finger protein 428
chr13_-_22219738 1.70 ENSMUST00000091742.6
H2A clustered histone 12
chr6_+_67890534 1.66 ENSMUST00000197406.5
ENSMUST00000103311.3
immunoglobulin kappa variable 11-125
chr7_+_24206482 1.64 ENSMUST00000071361.13
zinc finger protein 428
chr19_+_53128901 1.62 ENSMUST00000235754.2
ENSMUST00000237301.2
ENSMUST00000238130.2
adducin 3 (gamma)
chr10_-_79911245 1.59 ENSMUST00000217972.2
strawberry notch 2
chr13_+_23718038 1.59 ENSMUST00000073261.3
H2A clustered histone 10
chr5_+_76988444 1.56 ENSMUST00000120639.9
ENSMUST00000163347.8
ENSMUST00000121851.2
capping protein inhibiting regulator of actin
chr16_+_17051423 1.56 ENSMUST00000090190.14
ENSMUST00000232082.2
ENSMUST00000232426.2
hypermethylated in cancer 2
predicted gene, 49573
chr12_-_114398864 1.56 ENSMUST00000103489.2
immunoglobulin heavy variable 6-6
chr13_-_95661726 1.55 ENSMUST00000022185.10
coagulation factor II (thrombin) receptor-like 1
chr12_-_114117264 1.55 ENSMUST00000103461.5
immunoglobulin heavy variable 7-3
chr3_+_83673606 1.53 ENSMUST00000029625.8
secreted frizzled-related protein 2
chr12_-_114252202 1.52 ENSMUST00000195124.6
ENSMUST00000103481.3
immunoglobulin heavy variable 3-6
chr8_+_31640332 1.50 ENSMUST00000209851.2
ENSMUST00000098842.3
ENSMUST00000210129.2
TELO2 interacting protein 2
chr10_+_79763164 1.49 ENSMUST00000105376.2
AT rich interactive domain 3A (BRIGHT-like)
chr17_-_46867083 1.49 ENSMUST00000015749.7
serum response factor
chr12_-_114710326 1.48 ENSMUST00000103507.2
immunoglobulin heavy variable 1-22
chr9_+_21848282 1.47 ENSMUST00000046371.13
phospholipid phosphatase related 2
chr11_+_98632696 1.42 ENSMUST00000103139.11
thyroid hormone receptor alpha
chr12_-_115766700 1.42 ENSMUST00000196587.5
ENSMUST00000103543.3
immunoglobulin heavy variable V1-74
chr6_-_69753317 1.40 ENSMUST00000103366.3
immunoglobulin kappa chain variable 5-45
chr6_-_69704122 1.36 ENSMUST00000103364.3
immunoglobulin kappa variable 5-48
chr12_-_114621406 1.33 ENSMUST00000192077.2
immunoglobulin heavy variable 1-15
chr14_+_79753055 1.29 ENSMUST00000110835.3
ENSMUST00000227192.2
E74-like factor 1
chr6_-_67919524 1.26 ENSMUST00000196768.2
immunoglobulin kappa chain variable 9-124
chr13_+_23758555 1.23 ENSMUST00000090776.7
H2A clustered histone 7
chr6_-_69877961 1.22 ENSMUST00000197290.2
immunoglobulin kappa variable 5-39
chr1_+_12788720 1.22 ENSMUST00000088585.10
sulfatase 1
chr12_-_114286421 1.21 ENSMUST00000103483.3
immunoglobulin heavy variable V3-8
chr19_+_53128861 1.21 ENSMUST00000111741.10
adducin 3 (gamma)
chr15_+_102381705 1.17 ENSMUST00000229958.2
ENSMUST00000229184.2
ENSMUST00000230728.2
ENSMUST00000230114.2
poly(rC) binding protein 2
chr5_+_144127102 1.16 ENSMUST00000060747.8
basic helix-loop-helix family, member a15
chr6_-_87510200 1.15 ENSMUST00000113637.9
ENSMUST00000071024.7
Rho GTPase activating protein 25
chr13_-_23867924 1.14 ENSMUST00000171127.4
H2A clustered histone 6
chr1_+_75213082 1.13 ENSMUST00000055223.14
ENSMUST00000082158.13
ENSMUST00000188346.7
DnaJ heat shock protein family (Hsp40) member B2
chr3_+_129974531 1.13 ENSMUST00000080335.11
ENSMUST00000106353.2
collagen, type XXV, alpha 1
chr9_-_85209162 1.13 ENSMUST00000034802.15
terminal nucleotidyltransferase 5A
chr12_-_79239022 1.12 ENSMUST00000161204.8
retinol dehydrogenase 11
chr5_-_124003553 1.10 ENSMUST00000057145.7
hydroxycarboxylic acid receptor 2
chr9_-_85209340 1.10 ENSMUST00000187711.2
terminal nucleotidyltransferase 5A
chr6_+_68657317 1.10 ENSMUST00000198735.2
immunoglobulin kappa variable 10-95
chr4_+_128582519 1.10 ENSMUST00000106080.8
polyhomeotic 2
chr13_+_16186410 1.10 ENSMUST00000042603.14
inhibin beta-A
chr2_-_71198091 1.09 ENSMUST00000151937.8
solute carrier family 25 (mitochondrial carrier, Aralar), member 12
chr7_+_24206547 1.09 ENSMUST00000177205.2
zinc finger protein 428
chr6_+_68402550 1.08 ENSMUST00000103323.3
immunoglobulin kappa variable 16-104
chr12_-_113958518 1.07 ENSMUST00000103467.2
immunoglobulin heavy variable 14-2
chr17_-_59298338 1.06 ENSMUST00000025064.14
PDZ and pleckstrin homology domains 1
chr6_-_68857658 1.06 ENSMUST00000198756.2
predicted gene 42543
chr16_-_91525485 1.05 ENSMUST00000231499.2
ENSMUST00000141664.9
ENSMUST00000123751.2
ENSMUST00000122254.8
ENSMUST00000114023.3
crystallin, zeta (quinone reductase)-like 1
chr6_-_65121892 1.03 ENSMUST00000031982.5
hematopoietic prostaglandin D synthase
chr6_-_69877642 1.02 ENSMUST00000103370.3
immunoglobulin kappa variable 5-39
chr19_+_47926086 1.00 ENSMUST00000238163.2
ENSMUST00000066308.9
cilia and flagella associated protein 58
chrX_+_149377416 0.99 ENSMUST00000112713.3
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1
chr9_-_119812042 0.98 ENSMUST00000214058.2
cysteine-serine-rich nuclear protein 1
chr12_-_114023935 0.98 ENSMUST00000103469.4
immunoglobulin heavy variable V14-3
chr13_+_37529184 0.95 ENSMUST00000021860.7
lymphocyte antigen 86
chr10_-_79744726 0.95 ENSMUST00000165684.8
ENSMUST00000164705.8
ENSMUST00000105378.9
ENSMUST00000170409.2
mediator complex subunit 16
chr1_+_75213044 0.92 ENSMUST00000188931.7
DnaJ heat shock protein family (Hsp40) member B2
chr6_-_69835868 0.91 ENSMUST00000103369.2
immunoglobulin kappa chain variable 12-41
chr5_-_123126550 0.91 ENSMUST00000086200.11
ENSMUST00000156474.8
lysine (K)-specific demethylase 2B
chr5_-_123038329 0.91 ENSMUST00000031435.14
lysine (K)-specific demethylase 2B
chr12_-_115172211 0.91 ENSMUST00000103526.3
immunoglobulin heavy variable 1-55
chr7_-_44702269 0.90 ENSMUST00000057293.8
proline rich 12
chr16_-_4698148 0.89 ENSMUST00000037843.7
UBA-like domain containing 1
chr11_-_34724458 0.88 ENSMUST00000093191.3
spindle apparatus coiled-coil protein 1
chr2_+_118877594 0.88 ENSMUST00000152380.8
ENSMUST00000099542.9
kinetochore scaffold 1
chr11_+_83741689 0.88 ENSMUST00000108114.9
HNF1 homeobox B
chr4_+_3678108 0.87 ENSMUST00000041377.13
ENSMUST00000103010.4
LYN proto-oncogene, Src family tyrosine kinase
chr12_-_114672701 0.86 ENSMUST00000103505.3
ENSMUST00000193855.2
immunoglobulin heavy variable V1-19
chr6_-_148847854 0.86 ENSMUST00000139355.8
ENSMUST00000146457.2
ENSMUST00000054080.15
SIN3-HDAC complex associated factor
chr1_+_75213114 0.85 ENSMUST00000188290.7
DnaJ heat shock protein family (Hsp40) member B2
chr18_+_50184769 0.84 ENSMUST00000134348.8
ENSMUST00000153873.3
tumor necrosis factor, alpha-induced protein 8
chr6_+_70495224 0.83 ENSMUST00000103396.2
immunoglobulin kappa variable 3-12
chr3_+_159201048 0.83 ENSMUST00000120272.8
DEP domain containing 1a
chr8_+_70686836 0.82 ENSMUST00000164403.8
ENSMUST00000093458.11
SURP and G patch domain containing 2
chr12_-_114012399 0.82 ENSMUST00000103468.3
immunoglobulin heavy variable V11-2
chr3_+_96128427 0.81 ENSMUST00000090781.8
H2B clustered histone 21
chr3_-_97134680 0.80 ENSMUST00000046521.14
B cell CLL/lymphoma 9
chr11_+_98632953 0.79 ENSMUST00000153043.8
thyroid hormone receptor alpha
chr4_-_129590609 0.79 ENSMUST00000102588.10
transmembrane protein 39b
chr6_-_69940857 0.76 ENSMUST00000103372.3
immunoglobulin kappa variable 5-37
chr10_+_128542120 0.76 ENSMUST00000054125.9
premelanosome protein
chr19_-_40982576 0.76 ENSMUST00000117695.8
B cell linker
chr6_+_41098273 0.76 ENSMUST00000103270.4
T cell receptor beta, variable 13-2
chr12_-_115157739 0.74 ENSMUST00000103525.3
immunoglobulin heavy variable V1-54
chr8_-_70687051 0.73 ENSMUST00000019679.12
armadillo repeat containing 6
chr9_+_106099797 0.71 ENSMUST00000062241.11
toll-like receptor 9
chr6_+_67816777 0.70 ENSMUST00000200578.5
ENSMUST00000103308.3
immunoglobulin kappa variable 9-129
chrX_+_158155171 0.70 ENSMUST00000087143.7
eukaryotic translation initiation factor 1A, X-linked
chr15_-_93417380 0.69 ENSMUST00000109255.3
prickle planar cell polarity protein 1

Network of associatons between targets according to the STRING database.

First level regulatory network of Pou2f2_Pou3f1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
2.6 12.8 GO:1903288 positive regulation of potassium ion import(GO:1903288)
2.1 10.5 GO:0035519 protein K29-linked ubiquitination(GO:0035519)
1.9 26.5 GO:0000185 activation of MAPKKK activity(GO:0000185)
1.5 4.4 GO:0000448 cleavage in ITS2 between 5.8S rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000448)
1.2 3.7 GO:0043973 histone H3-K4 acetylation(GO:0043973)
1.1 4.5 GO:0017055 negative regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0017055)
1.1 4.2 GO:0046898 response to cycloheximide(GO:0046898)
0.8 2.3 GO:1904172 positive regulation of bleb assembly(GO:1904172)
0.8 1.5 GO:0070948 regulation of neutrophil mediated cytotoxicity(GO:0070948) regulation of neutrophil mediated killing of symbiont cell(GO:0070949)
0.7 7.5 GO:0051025 negative regulation of immunoglobulin secretion(GO:0051025)
0.7 1.5 GO:0003257 positive regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation(GO:0003257)
0.7 7.4 GO:2000774 positive regulation of cellular senescence(GO:2000774)
0.6 1.8 GO:0060447 bud outgrowth involved in lung branching(GO:0060447)
0.6 2.4 GO:0021993 initiation of neural tube closure(GO:0021993)
0.6 10.4 GO:0045199 maintenance of epithelial cell apical/basal polarity(GO:0045199)
0.6 6.7 GO:1902033 vitamin D receptor signaling pathway(GO:0070561) regulation of hematopoietic stem cell proliferation(GO:1902033)
0.5 8.7 GO:0051152 positive regulation of smooth muscle cell differentiation(GO:0051152)
0.5 1.5 GO:1904956 regulation of midbrain dopaminergic neuron differentiation(GO:1904956) regulation of planar cell polarity pathway involved in axis elongation(GO:2000040) negative regulation of planar cell polarity pathway involved in axis elongation(GO:2000041)
0.5 69.2 GO:0006910 phagocytosis, recognition(GO:0006910)
0.5 2.3 GO:0045347 negative regulation of MHC class II biosynthetic process(GO:0045347)
0.4 2.9 GO:1903644 regulation of chaperone-mediated protein folding(GO:1903644)
0.4 1.6 GO:0071348 cellular response to interleukin-11(GO:0071348)
0.4 1.6 GO:0035565 regulation of pronephros size(GO:0035565) mesonephros morphogenesis(GO:0061206) mesonephric nephron development(GO:0061215) mesonephric nephron morphogenesis(GO:0061228) mesenchymal stem cell maintenance involved in mesonephric nephron morphogenesis(GO:0061235) regulation of mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis(GO:0061295) negative regulation of mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis(GO:0061296) mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis(GO:1901146)
0.4 2.7 GO:0035799 ureter maturation(GO:0035799)
0.4 0.7 GO:0032741 positive regulation of interleukin-18 production(GO:0032741)
0.3 3.0 GO:0006265 DNA topological change(GO:0006265)
0.3 2.6 GO:0002326 B cell lineage commitment(GO:0002326)
0.3 3.6 GO:1902746 regulation of lens fiber cell differentiation(GO:1902746)
0.3 3.3 GO:0016446 somatic hypermutation of immunoglobulin genes(GO:0016446)
0.3 0.9 GO:2000670 positive regulation of dendritic cell apoptotic process(GO:2000670)
0.3 15.7 GO:0006284 base-excision repair(GO:0006284)
0.3 1.1 GO:0036367 adaptation of rhodopsin mediated signaling(GO:0016062) light adaption(GO:0036367)
0.3 2.7 GO:0030916 otic vesicle formation(GO:0030916)
0.3 0.8 GO:0014908 myotube differentiation involved in skeletal muscle regeneration(GO:0014908)
0.3 6.6 GO:0019370 glutathione biosynthetic process(GO:0006750) leukotriene biosynthetic process(GO:0019370)
0.2 4.5 GO:0070995 NADPH oxidation(GO:0070995)
0.2 0.7 GO:0051892 negative regulation of cardioblast differentiation(GO:0051892)
0.2 1.1 GO:0060279 positive regulation of ovulation(GO:0060279)
0.2 1.1 GO:0043490 malate-aspartate shuttle(GO:0043490)
0.2 0.6 GO:1904268 regulation of Schwann cell chemotaxis(GO:1904266) positive regulation of Schwann cell chemotaxis(GO:1904268) Schwann cell chemotaxis(GO:1990751)
0.2 1.8 GO:0035405 histone-threonine phosphorylation(GO:0035405)
0.2 1.2 GO:0014846 esophagus smooth muscle contraction(GO:0014846) glial cell-derived neurotrophic factor receptor signaling pathway(GO:0035860)
0.2 2.3 GO:0048170 positive regulation of long-term neuronal synaptic plasticity(GO:0048170)
0.2 4.0 GO:0046085 adenosine metabolic process(GO:0046085)
0.2 0.6 GO:0002380 immunoglobulin secretion involved in immune response(GO:0002380)
0.2 1.0 GO:2000255 negative regulation of male germ cell proliferation(GO:2000255)
0.2 0.5 GO:0031554 regulation of DNA-templated transcription, termination(GO:0031554)
0.2 2.7 GO:0002043 blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:0002043)
0.2 7.2 GO:0006779 porphyrin-containing compound biosynthetic process(GO:0006779)
0.1 1.8 GO:2000111 primary heart field specification(GO:0003138) sinoatrial valve development(GO:0003172) sinoatrial valve morphogenesis(GO:0003185) positive regulation of macrophage apoptotic process(GO:2000111)
0.1 1.1 GO:0060385 axonogenesis involved in innervation(GO:0060385)
0.1 1.1 GO:0070162 adiponectin secretion(GO:0070162) regulation of adiponectin secretion(GO:0070163)
0.1 0.6 GO:0072368 regulation of lipid transport by negative regulation of transcription from RNA polymerase II promoter(GO:0072368)
0.1 28.3 GO:0002377 immunoglobulin production(GO:0002377)
0.1 1.8 GO:0034501 protein localization to kinetochore(GO:0034501)
0.1 0.5 GO:1903445 intermembrane transport(GO:0046909) protein transport from ciliary membrane to plasma membrane(GO:1903445)
0.1 0.8 GO:0033484 nitric oxide homeostasis(GO:0033484)
0.1 0.2 GO:0060435 bronchiole development(GO:0060435)
0.1 1.0 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.1 0.5 GO:1905066 canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:0061317) blood vessel lumenization(GO:0072554) regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901295) positive regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901297) regulation of canonical Wnt signaling pathway involved in heart development(GO:1905066) positive regulation of canonical Wnt signaling pathway involved in heart development(GO:1905068)
0.1 5.4 GO:0050853 B cell receptor signaling pathway(GO:0050853)
0.1 2.4 GO:0045898 regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045898)
0.1 0.5 GO:2000210 positive regulation of anoikis(GO:2000210)
0.1 0.8 GO:0018401 peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401)
0.1 0.3 GO:0016332 establishment or maintenance of polarity of embryonic epithelium(GO:0016332)
0.1 0.8 GO:0048023 positive regulation of melanin biosynthetic process(GO:0048023) positive regulation of secondary metabolite biosynthetic process(GO:1900378)
0.1 8.0 GO:0038083 peptidyl-tyrosine autophosphorylation(GO:0038083)
0.1 2.6 GO:0002076 osteoblast development(GO:0002076)
0.1 6.1 GO:0001541 ovarian follicle development(GO:0001541)
0.1 0.3 GO:0060800 regulation of cell differentiation involved in embryonic placenta development(GO:0060800)
0.1 0.4 GO:0048539 bone marrow development(GO:0048539)
0.1 2.4 GO:0030539 male genitalia development(GO:0030539)
0.1 0.2 GO:0055096 lipoprotein particle mediated signaling(GO:0055095) low-density lipoprotein particle mediated signaling(GO:0055096)
0.1 2.1 GO:0001886 endothelial cell morphogenesis(GO:0001886)
0.1 0.6 GO:2000121 regulation of removal of superoxide radicals(GO:2000121)
0.1 4.5 GO:0035307 positive regulation of protein dephosphorylation(GO:0035307)
0.1 4.5 GO:0060325 face morphogenesis(GO:0060325)
0.1 0.2 GO:1900248 cytoplasmic translational elongation(GO:0002182) regulation of cytoplasmic translational elongation(GO:1900247) negative regulation of cytoplasmic translational elongation(GO:1900248)
0.1 0.4 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
0.1 1.2 GO:0006851 mitochondrial calcium ion transport(GO:0006851)
0.1 0.6 GO:1900383 regulation of synaptic plasticity by receptor localization to synapse(GO:1900383)
0.1 3.6 GO:0010762 regulation of fibroblast migration(GO:0010762)
0.1 4.4 GO:0051865 protein autoubiquitination(GO:0051865)
0.1 3.8 GO:0060395 SMAD protein signal transduction(GO:0060395)
0.1 0.3 GO:0050916 sensory perception of sweet taste(GO:0050916)
0.1 1.2 GO:0075522 IRES-dependent viral translational initiation(GO:0075522)
0.1 0.3 GO:0051835 positive regulation of synapse structural plasticity(GO:0051835)
0.0 1.3 GO:0050858 negative regulation of antigen receptor-mediated signaling pathway(GO:0050858) negative regulation of T cell receptor signaling pathway(GO:0050860)
0.0 7.1 GO:0007338 single fertilization(GO:0007338)
0.0 0.2 GO:0060157 urinary bladder development(GO:0060157)
0.0 0.5 GO:0002002 regulation of angiotensin levels in blood(GO:0002002)
0.0 0.1 GO:0071336 regulation of hair follicle cell proliferation(GO:0071336)
0.0 0.4 GO:0010606 positive regulation of cytoplasmic mRNA processing body assembly(GO:0010606)
0.0 0.6 GO:0048935 peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.0 0.9 GO:0021516 dorsal spinal cord development(GO:0021516)
0.0 0.2 GO:0036414 protein citrullination(GO:0018101) histone citrullination(GO:0036414)
0.0 0.6 GO:0090161 Golgi ribbon formation(GO:0090161)
0.0 0.2 GO:0090158 endoplasmic reticulum membrane organization(GO:0090158)
0.0 1.1 GO:0030225 macrophage differentiation(GO:0030225)
0.0 1.5 GO:0046839 phospholipid dephosphorylation(GO:0046839)
0.0 0.6 GO:0007095 mitotic G2 DNA damage checkpoint(GO:0007095)
0.0 0.1 GO:1902202 regulation of hepatocyte growth factor receptor signaling pathway(GO:1902202)
0.0 0.3 GO:0098703 calcium ion import across plasma membrane(GO:0098703) calcium ion import into cell(GO:1990035)
0.0 0.4 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
0.0 0.3 GO:0036158 outer dynein arm assembly(GO:0036158)
0.0 0.2 GO:0006032 chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032)
0.0 0.1 GO:0089711 L-glutamate transmembrane transport(GO:0089711)
0.0 1.2 GO:1902476 chloride transmembrane transport(GO:1902476)
0.0 0.4 GO:0030033 microvillus assembly(GO:0030033)
0.0 2.8 GO:0043524 negative regulation of neuron apoptotic process(GO:0043524)
0.0 0.3 GO:0002115 store-operated calcium entry(GO:0002115)
0.0 0.3 GO:0007614 short-term memory(GO:0007614)
0.0 1.9 GO:1903169 regulation of calcium ion transmembrane transport(GO:1903169)
0.0 0.1 GO:0018231 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.0 0.6 GO:0010501 RNA secondary structure unwinding(GO:0010501)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
2.0 15.7 GO:0035985 senescence-associated heterochromatin focus(GO:0035985)
1.5 4.5 GO:1990031 pinceau fiber(GO:1990031)
1.3 12.8 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.6 75.0 GO:0019814 immunoglobulin complex(GO:0019814)
0.5 2.6 GO:0035976 AP1 complex(GO:0035976)
0.4 3.0 GO:0031298 replication fork protection complex(GO:0031298)
0.4 1.1 GO:0043512 inhibin A complex(GO:0043512)
0.3 1.0 GO:0043540 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex(GO:0043540)
0.3 10.5 GO:0005680 anaphase-promoting complex(GO:0005680)
0.3 4.2 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.3 2.3 GO:0005826 actomyosin contractile ring(GO:0005826)
0.2 2.8 GO:0000788 nuclear nucleosome(GO:0000788)
0.2 0.9 GO:0034666 integrin alpha2-beta1 complex(GO:0034666)
0.2 5.6 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.1 0.4 GO:0048269 methionine adenosyltransferase complex(GO:0048269)
0.1 0.6 GO:0071953 elastic fiber(GO:0071953)
0.1 0.7 GO:0036019 endolysosome(GO:0036019)
0.1 0.4 GO:0008623 CHRAC(GO:0008623)
0.1 0.4 GO:0031251 PAN complex(GO:0031251)
0.1 0.8 GO:0032585 multivesicular body membrane(GO:0032585)
0.1 0.6 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.1 2.1 GO:0090545 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.1 1.5 GO:0031143 pseudopodium(GO:0031143)
0.1 9.9 GO:0016605 PML body(GO:0016605)
0.1 29.7 GO:0016607 nuclear speck(GO:0016607)
0.1 0.9 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.1 1.1 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.1 0.6 GO:0060091 kinocilium(GO:0060091)
0.0 9.8 GO:0031227 intrinsic component of endoplasmic reticulum membrane(GO:0031227)
0.0 2.5 GO:0097440 apical dendrite(GO:0097440)
0.0 3.1 GO:0031519 PcG protein complex(GO:0031519)
0.0 0.2 GO:0014701 junctional sarcoplasmic reticulum membrane(GO:0014701)
0.0 0.9 GO:0000777 condensed chromosome kinetochore(GO:0000777)
0.0 0.6 GO:0005640 nuclear outer membrane(GO:0005640)
0.0 0.5 GO:0070822 Sin3-type complex(GO:0070822)
0.0 0.3 GO:0036157 outer dynein arm(GO:0036157)
0.0 0.2 GO:0000308 cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308)
0.0 2.7 GO:0005905 clathrin-coated pit(GO:0005905)
0.0 0.3 GO:0072669 tRNA-splicing ligase complex(GO:0072669)
0.0 0.9 GO:0016592 mediator complex(GO:0016592)
0.0 4.7 GO:0005903 brush border(GO:0005903)
0.0 0.4 GO:0098563 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.0 0.1 GO:0033269 internode region of axon(GO:0033269)
0.0 2.9 GO:0045111 intermediate filament cytoskeleton(GO:0045111)
0.0 0.9 GO:0005801 cis-Golgi network(GO:0005801)
0.0 0.5 GO:0043596 nuclear replication fork(GO:0043596)
0.0 6.3 GO:0005635 nuclear envelope(GO:0005635)
0.0 0.6 GO:0031201 SNARE complex(GO:0031201)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.7 15.7 GO:0051575 5'-deoxyribose-5-phosphate lyase activity(GO:0051575)
1.6 6.6 GO:0004464 leukotriene-C4 synthase activity(GO:0004464)
1.5 6.1 GO:0004105 choline-phosphate cytidylyltransferase activity(GO:0004105)
1.1 4.5 GO:0002153 steroid receptor RNA activator RNA binding(GO:0002153)
1.1 12.8 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
1.0 3.0 GO:0097100 supercoiled DNA binding(GO:0097100)
0.7 7.2 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.6 4.4 GO:0051731 polynucleotide 5'-hydroxyl-kinase activity(GO:0051731)
0.6 2.3 GO:0045183 translation factor activity, non-nucleic acid binding(GO:0045183)
0.5 69.2 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.5 6.7 GO:0043024 ribosomal small subunit binding(GO:0043024)
0.4 4.2 GO:0051434 BH3 domain binding(GO:0051434)
0.4 1.5 GO:0015057 thrombin receptor activity(GO:0015057)
0.3 2.6 GO:0070644 vitamin D response element binding(GO:0070644)
0.3 1.0 GO:0004667 prostaglandin-D synthase activity(GO:0004667)
0.2 3.7 GO:0030274 LIM domain binding(GO:0030274)
0.2 1.1 GO:0015183 L-aspartate transmembrane transporter activity(GO:0015183)
0.2 0.9 GO:0005128 erythropoietin receptor binding(GO:0005128)
0.2 5.6 GO:0004033 aldo-keto reductase (NADP) activity(GO:0004033)
0.2 10.5 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.2 1.8 GO:0045545 syndecan binding(GO:0045545)
0.2 3.6 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.2 1.2 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.2 8.7 GO:0003785 actin monomer binding(GO:0003785)
0.2 1.8 GO:0035184 histone threonine kinase activity(GO:0035184)
0.2 4.0 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.2 2.7 GO:0016918 retinal binding(GO:0016918)
0.2 0.6 GO:0000822 inositol hexakisphosphate binding(GO:0000822)
0.2 1.1 GO:0070699 type II activin receptor binding(GO:0070699)
0.2 2.3 GO:0051525 NFAT protein binding(GO:0051525)
0.1 0.7 GO:0045322 unmethylated CpG binding(GO:0045322)
0.1 1.5 GO:0061133 endopeptidase activator activity(GO:0061133)
0.1 30.4 GO:0047485 protein N-terminus binding(GO:0047485)
0.1 0.9 GO:0030375 thyroid hormone receptor coactivator activity(GO:0030375)
0.1 2.9 GO:0070628 proteasome binding(GO:0070628)
0.1 2.4 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.1 0.9 GO:0043515 kinetochore binding(GO:0043515)
0.1 7.2 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.1 1.0 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873)
0.1 5.8 GO:0005246 calcium channel regulator activity(GO:0005246)
0.1 3.8 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.1 3.2 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.1 0.3 GO:0015275 stretch-activated, cation-selective, calcium channel activity(GO:0015275)
0.1 1.5 GO:0042577 lipid phosphatase activity(GO:0042577)
0.1 0.3 GO:0004756 selenide, water dikinase activity(GO:0004756) phosphotransferase activity, paired acceptors(GO:0016781)
0.1 1.2 GO:1990829 C-rich single-stranded DNA binding(GO:1990829)
0.1 1.1 GO:0070878 primary miRNA binding(GO:0070878)
0.1 0.4 GO:0004594 pantothenate kinase activity(GO:0004594)
0.1 0.7 GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.1 0.8 GO:0031545 peptidyl-proline 4-dioxygenase activity(GO:0031545)
0.1 1.8 GO:0035198 miRNA binding(GO:0035198)
0.0 0.2 GO:0051373 FATZ binding(GO:0051373)
0.0 3.0 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.0 3.0 GO:0019003 GDP binding(GO:0019003)
0.0 3.8 GO:0003823 antigen binding(GO:0003823)
0.0 1.1 GO:0001614 purinergic nucleotide receptor activity(GO:0001614) nucleotide receptor activity(GO:0016502)
0.0 0.2 GO:0004668 protein-arginine deiminase activity(GO:0004668)
0.0 1.2 GO:0070064 proline-rich region binding(GO:0070064)
0.0 0.7 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.0 0.3 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.0 0.5 GO:1990226 histone methyltransferase binding(GO:1990226)
0.0 1.0 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.0 0.3 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.0 0.1 GO:0005171 hepatocyte growth factor receptor binding(GO:0005171)
0.0 0.1 GO:0000099 sulfur amino acid transmembrane transporter activity(GO:0000099)
0.0 1.3 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 0.2 GO:0004568 chitinase activity(GO:0004568)
0.0 0.6 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 0.4 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.0 2.9 GO:0030674 protein binding, bridging(GO:0030674)
0.0 0.8 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0 0.2 GO:0004126 cytidine deaminase activity(GO:0004126)
0.0 0.8 GO:0051959 dynein light intermediate chain binding(GO:0051959)
0.0 0.5 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.0 1.0 GO:0001540 beta-amyloid binding(GO:0001540)
0.0 0.8 GO:0048487 beta-tubulin binding(GO:0048487)
0.0 0.6 GO:0005484 SNAP receptor activity(GO:0005484)
0.0 0.2 GO:0005527 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0 0.1 GO:0015526 hexose phosphate transmembrane transporter activity(GO:0015119) organophosphate:inorganic phosphate antiporter activity(GO:0015315) hexose-phosphate:inorganic phosphate antiporter activity(GO:0015526) glucose 6-phosphate:inorganic phosphate antiporter activity(GO:0061513)
0.0 0.2 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.0 0.5 GO:0051059 NF-kappaB binding(GO:0051059)
0.0 0.3 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.0 0.3 GO:0097602 cullin family protein binding(GO:0097602)
0.0 0.4 GO:0030742 GTP-dependent protein binding(GO:0030742)
0.0 0.7 GO:0003743 translation initiation factor activity(GO:0003743)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 27.2 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.2 20.1 PID IL4 2PATHWAY IL4-mediated signaling events
0.2 7.6 PID IL5 PATHWAY IL5-mediated signaling events
0.1 4.8 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.1 1.8 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.1 3.2 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining
0.1 6.6 PID BCR 5PATHWAY BCR signaling pathway
0.1 4.8 PID EPHB FWD PATHWAY EPHB forward signaling
0.1 0.6 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.1 0.6 PID EPHA2 FWD PATHWAY EPHA2 forward signaling
0.1 1.5 ST GA12 PATHWAY G alpha 12 Pathway
0.1 1.8 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.1 9.9 PID PDGFRB PATHWAY PDGFR-beta signaling pathway
0.1 3.1 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 1.8 PID MAPK TRK PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.0 1.1 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.0 3.3 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.0 0.8 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0 1.1 PID ALK1 PATHWAY ALK1 signaling events
0.0 2.5 PID HDAC CLASSI PATHWAY Signaling events mediated by HDAC Class I
0.0 0.6 ST WNT CA2 CYCLIC GMP PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.0 0.5 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.0 2.8 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors
0.0 0.8 NABA COLLAGENS Genes encoding collagen proteins
0.0 0.3 PID CD8 TCR PATHWAY TCR signaling in naïve CD8+ T cells

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
2.2 15.7 REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.3 12.9 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.2 4.0 REACTOME PYRIMIDINE CATABOLISM Genes involved in Pyrimidine catabolism
0.2 6.1 REACTOME SYNTHESIS OF PC Genes involved in Synthesis of PC
0.2 4.2 REACTOME INFLAMMASOMES Genes involved in Inflammasomes
0.2 3.2 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.2 8.4 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.1 6.6 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.1 5.1 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.1 1.1 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.1 0.8 REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.1 10.6 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.1 21.0 REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.1 3.9 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.1 0.7 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.0 2.1 REACTOME GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.0 3.9 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.0 0.6 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0 1.8 REACTOME ERK MAPK TARGETS Genes involved in ERK/MAPK targets
0.0 0.4 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.0 0.5 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.0 1.1 REACTOME METABOLISM OF STEROID HORMONES AND VITAMINS A AND D Genes involved in Metabolism of steroid hormones and vitamins A and D
0.0 0.8 REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.0 0.4 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.0 0.8 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 1.2 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.0 0.1 REACTOME RNA POL I PROMOTER OPENING Genes involved in RNA Polymerase I Promoter Opening
0.0 0.7 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex