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GSE58827: Dynamics of the Mouse Liver

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Results for Prdm1

Z-value: 0.86

Motif logo

Transcription factors associated with Prdm1

Gene Symbol Gene ID Gene Info
ENSMUSG00000038151.14 PR domain containing 1, with ZNF domain

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Prdm1mm39_v1_chr10_-_44334711_44334747-0.231.9e-01Click!

Activity profile of Prdm1 motif

Sorted Z-values of Prdm1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr19_+_40078132 8.55 ENSMUST00000068094.13
ENSMUST00000080171.3
cytochrome P450, family 2, subfamily c, polypeptide 50
chr6_-_55152002 7.99 ENSMUST00000003569.6
indolethylamine N-methyltransferase
chr15_+_77613239 7.99 ENSMUST00000230979.2
ENSMUST00000109775.4
apolipoprotein L 9b
chr15_+_77613348 5.85 ENSMUST00000230742.2
apolipoprotein L 9b
chr5_+_31078775 4.92 ENSMUST00000201621.4
ketohexokinase
chr8_-_45786226 4.45 ENSMUST00000095328.6
cytochrome P450, family 4, subfamily v, polypeptide 3
chr15_+_33083358 4.27 ENSMUST00000228916.2
ENSMUST00000226483.2
ENSMUST00000228737.2
carboxypeptidase Q
chr6_-_48549594 4.11 ENSMUST00000009425.7
ENSMUST00000204267.3
ENSMUST00000204930.3
ENSMUST00000204182.2
retinoic acid receptor responder (tazarotene induced) 2
chr5_+_31078911 3.66 ENSMUST00000201571.4
ketohexokinase
chr3_-_113368407 3.58 ENSMUST00000106540.8
amylase 1, salivary
chr14_+_40827317 3.48 ENSMUST00000047286.7
methionine adenosyltransferase I, alpha
chr11_-_5900019 3.26 ENSMUST00000102920.4
glucokinase
chr8_+_70536103 3.19 ENSMUST00000007738.11
hyaluronan and proteoglycan link protein 4
chr3_+_129630380 3.17 ENSMUST00000077918.7
complement component factor i
chr14_+_40826970 3.14 ENSMUST00000225720.2
methionine adenosyltransferase I, alpha
chr14_+_40827108 3.02 ENSMUST00000224514.2
methionine adenosyltransferase I, alpha
chr8_-_93956143 2.90 ENSMUST00000176282.2
ENSMUST00000034173.14
carboxylesterase 1E
chr15_+_25843225 2.88 ENSMUST00000022881.15
reticulophagy regulator 1
chr8_-_85526653 2.84 ENSMUST00000126806.2
ENSMUST00000076715.13
nuclear factor I/X
chr9_-_106353792 2.78 ENSMUST00000214682.2
ENSMUST00000112479.9
poly (ADP-ribose) polymerase family, member 3
chr4_-_107928567 2.72 ENSMUST00000106701.2
sterol carrier protein 2, liver
chr15_+_100202642 2.70 ENSMUST00000067752.5
ENSMUST00000229588.2
methyltransferase like 7A1
chr6_+_117145496 2.50 ENSMUST00000112866.8
ENSMUST00000112871.8
ENSMUST00000073043.5
chemokine (C-X-C motif) ligand 12
chr10_+_116137277 2.49 ENSMUST00000092167.7
protein tyrosine phosphatase, receptor type, B
chr9_-_106353571 2.45 ENSMUST00000123555.8
ENSMUST00000125850.2
poly (ADP-ribose) polymerase family, member 3
chr4_-_42756489 2.45 ENSMUST00000140546.3
ENSMUST00000102957.6
chemokine (C-C motif) ligand 19
chr11_-_73215442 2.45 ENSMUST00000021119.9
aspartoacylase
chr3_+_81839908 2.29 ENSMUST00000029649.3
cathepsin O
chr9_-_107546166 2.28 ENSMUST00000177567.8
solute carrier family 38, member 3
chr4_-_42773987 2.25 ENSMUST00000095114.5
chemokine (C-C motif) ligand 21A (serine)
chr8_-_85526972 2.24 ENSMUST00000099070.10
nuclear factor I/X
chr2_+_43445333 2.22 ENSMUST00000028223.9
ENSMUST00000112826.8
kynureninase
chr6_-_23839136 2.12 ENSMUST00000166458.9
ENSMUST00000142913.9
ENSMUST00000069074.14
ENSMUST00000115361.9
ENSMUST00000018122.14
ENSMUST00000115356.3
Ca2+-dependent activator protein for secretion 2
chr11_+_120421496 2.08 ENSMUST00000026119.8
glucagon receptor
chr11_-_120618052 2.06 ENSMUST00000106148.10
ENSMUST00000026144.5
dicarbonyl L-xylulose reductase
chr3_+_122688721 1.99 ENSMUST00000023820.6
fatty acid binding protein 2, intestinal
chr8_+_127790772 1.95 ENSMUST00000079777.12
ENSMUST00000160272.8
ENSMUST00000162907.8
ENSMUST00000162536.8
ENSMUST00000026921.13
ENSMUST00000162665.8
ENSMUST00000162602.8
ENSMUST00000160581.8
ENSMUST00000161355.8
ENSMUST00000162531.8
ENSMUST00000160766.8
ENSMUST00000159537.8
par-3 family cell polarity regulator
chr13_+_74787952 1.90 ENSMUST00000221822.2
ENSMUST00000221526.2
endoplasmic reticulum aminopeptidase 1
chr17_-_32643067 1.87 ENSMUST00000237130.2
peptidoglycan recognition protein 2
chr12_+_37292029 1.78 ENSMUST00000160390.2
alkylglycerol monooxygenase
chr2_+_43445359 1.77 ENSMUST00000050511.7
kynureninase
chr15_+_32920869 1.73 ENSMUST00000022871.7
syndecan 2
chr9_-_44714263 1.71 ENSMUST00000044694.8
tetratricopeptide repeat domain 36
chr3_-_107952146 1.66 ENSMUST00000178808.8
ENSMUST00000106670.2
ENSMUST00000029489.15
glutathione S-transferase, mu 4
chr14_-_73622638 1.66 ENSMUST00000228637.2
ENSMUST00000022704.9
integral membrane protein 2B
chr11_+_102993865 1.62 ENSMUST00000152971.2
acyl-Coenzyme A binding domain containing 4
chr14_-_45715308 1.61 ENSMUST00000141424.2
fermitin family member 2
chr9_-_107546195 1.60 ENSMUST00000192990.6
solute carrier family 38, member 3
chr10_+_128158413 1.58 ENSMUST00000219836.2
canopy FGF signaling regulator 2
chr1_+_139429430 1.55 ENSMUST00000027615.7
coagulation factor XIII, beta subunit
chr3_+_145464413 1.53 ENSMUST00000029845.15
dimethylarginine dimethylaminohydrolase 1
chr12_+_37291632 1.51 ENSMUST00000049874.14
alkylglycerol monooxygenase
chr3_+_142406827 1.44 ENSMUST00000044392.11
ENSMUST00000199519.5
kynurenine aminotransferase 3
chr13_-_12479804 1.43 ENSMUST00000124888.8
lectin, galactose binding, soluble 8
chr18_-_13013030 1.40 ENSMUST00000119512.8
oxysterol binding protein-like 1A
chr11_-_77784922 1.38 ENSMUST00000017597.5
pipecolic acid oxidase
chr10_-_95159933 1.37 ENSMUST00000053594.7
CASP2 and RIPK1 domain containing adaptor with death domain
chr10_+_128158328 1.36 ENSMUST00000219037.2
ENSMUST00000026446.4
canopy FGF signaling regulator 2
chr1_-_184578057 1.36 ENSMUST00000068725.10
mitochondrial amidoxime reducing component 2
chr17_+_34138611 1.34 ENSMUST00000234247.2
TAP binding protein
chr2_+_68966125 1.34 ENSMUST00000041865.8
nitric oxide synthase trafficker
chr16_-_30086317 1.34 ENSMUST00000064856.9
carboxypeptidase N, polypeptide 2
chr17_-_34406193 1.33 ENSMUST00000173831.3
proteasome (prosome, macropain) subunit, beta type 9 (large multifunctional peptidase 2)
chr3_-_101511971 1.33 ENSMUST00000036493.8
ATPase, Na+/K+ transporting, alpha 1 polypeptide
chr14_+_64890008 1.32 ENSMUST00000224503.2
kinesin family member 13B
chr13_+_33188511 1.32 ENSMUST00000006391.5
serine (or cysteine) peptidase inhibitor, clade B, member 9
chr3_+_142406787 1.32 ENSMUST00000106218.8
kynurenine aminotransferase 3
chr12_+_37291728 1.31 ENSMUST00000160768.8
alkylglycerol monooxygenase
chr15_-_89263448 1.26 ENSMUST00000049968.9
outer dense fiber of sperm tails 3B
chr4_+_42114817 1.24 ENSMUST00000098123.4
predicted gene 13304
chr14_-_25927674 1.24 ENSMUST00000100811.6
transmembrane protein 254a
chr15_-_89263790 1.23 ENSMUST00000238996.2
outer dense fiber of sperm tails 3B
chr5_-_105387395 1.23 ENSMUST00000065588.7
guanylate-binding protein 10
chr13_+_24023428 1.22 ENSMUST00000091698.12
ENSMUST00000110422.3
ENSMUST00000166467.9
solute carrier family 17 (sodium phosphate), member 3
chr1_-_106687457 1.22 ENSMUST00000010049.6
3-ketodihydrosphingosine reductase
chr4_-_25281750 1.20 ENSMUST00000038705.8
ENSMUST00000102994.10
UFM1 specific ligase 1
chr17_+_37504783 1.20 ENSMUST00000038844.7
ubiquitin D
chr5_+_92285748 1.19 ENSMUST00000031355.10
ENSMUST00000202155.2
USO1 vesicle docking factor
chr4_-_96479793 1.17 ENSMUST00000055693.9
cytochrome P450, family 2, subfamily j, polypeptide 9
chr4_+_41903610 1.17 ENSMUST00000098128.4
chemokine (C-C motif) ligand 21D
chr4_-_148236516 1.15 ENSMUST00000056965.12
ENSMUST00000168503.8
ENSMUST00000152098.8
F-box protein 6
chr14_+_52122299 1.15 ENSMUST00000047899.13
ENSMUST00000164902.8
methyltransferase like 17
chr4_+_42255693 1.15 ENSMUST00000178864.3
chemokine (C-C motif) ligand 21B (leucine)
chr14_+_64889973 1.13 ENSMUST00000100473.5
kinesin family member 13B
chr17_+_34138699 1.12 ENSMUST00000234320.2
TAP binding protein
chr2_+_85850977 1.11 ENSMUST00000213774.2
ENSMUST00000214546.2
ENSMUST00000215682.2
olfactory receptor 1033
chr3_+_106629209 1.08 ENSMUST00000106736.3
ENSMUST00000154973.2
ENSMUST00000098750.5
ENSMUST00000150513.2
ligand dependent nuclear receptor interacting factor 1
chr14_-_101878106 1.07 ENSMUST00000100339.9
COMM domain containing 6
chr16_-_35691914 1.07 ENSMUST00000042665.9
poly (ADP-ribose) polymerase family, member 14
chr1_+_177269845 1.07 ENSMUST00000195002.2
zinc finger and BTB domain containing 18
chr14_-_55909527 1.05 ENSMUST00000010520.10
neural precursor cell expressed, developmentally down-regulated gene 8
chr2_+_11710101 1.04 ENSMUST00000138349.8
ENSMUST00000135341.8
ENSMUST00000128156.9
interleukin 15 receptor, alpha chain
chr17_-_13135232 1.03 ENSMUST00000079121.4
mitochondrial ribosomal protein L18
chr2_-_155661324 1.02 ENSMUST00000124586.2
cDNA sequence BC029722
chr8_+_89423645 1.02 ENSMUST00000043526.15
ENSMUST00000211554.2
ENSMUST00000209532.2
ENSMUST00000209559.2
CYLD lysine 63 deubiquitinase
chr5_+_115061293 1.02 ENSMUST00000031540.11
ENSMUST00000112143.4
2'-5' oligoadenylate synthetase-like 1
chr1_+_91226058 0.98 ENSMUST00000027532.13
selenocysteine lyase
chr3_-_65300000 0.97 ENSMUST00000029414.12
signal sequence receptor, gamma
chr13_+_24023386 0.95 ENSMUST00000039721.14
solute carrier family 17 (sodium phosphate), member 3
chr8_+_95161006 0.93 ENSMUST00000211816.2
NLR family, CARD domain containing 5
chr16_-_38533597 0.92 ENSMUST00000023487.5
Rho GTPase activating protein 31
chr11_-_120464062 0.91 ENSMUST00000026122.11
prolyl 4-hydroxylase, beta polypeptide
chr13_-_92620507 0.90 ENSMUST00000040106.9
family with sequence similarity 151, member B
chr1_-_183766195 0.89 ENSMUST00000050306.8
RIKEN cDNA 1700056E22 gene
chr4_+_42612121 0.86 ENSMUST00000178168.3
predicted gene 10591
chr14_-_101877870 0.85 ENSMUST00000168587.3
COMM domain containing 6
chr8_-_106665060 0.84 ENSMUST00000034369.10
proteasome (prosome, macropain) subunit, beta type 10
chr17_+_34043536 0.83 ENSMUST00000048249.8
NADH:ubiquinone oxidoreductase subunit A7
chr2_+_11710523 0.83 ENSMUST00000138856.2
ENSMUST00000078834.12
ENSMUST00000114834.10
ENSMUST00000114833.10
ENSMUST00000114831.9
interleukin 15 receptor, alpha chain
chr4_-_45489794 0.83 ENSMUST00000146236.8
src homology 2 domain-containing transforming protein B
chr6_+_40619913 0.83 ENSMUST00000238599.2
maltase-glucoamylase
chr1_-_172418058 0.82 ENSMUST00000065679.8
SLAM family member 8
chr11_-_120463667 0.80 ENSMUST00000168360.2
prolyl 4-hydroxylase, beta polypeptide
chr13_+_104953679 0.80 ENSMUST00000022230.15
splicing regulatory glutamine/lysine-rich protein 1interacting protein 1
chr6_-_39095144 0.79 ENSMUST00000038398.7
poly (ADP-ribose) polymerase family, member 12
chr11_-_53750016 0.79 ENSMUST00000117316.8
ENSMUST00000120776.8
ENSMUST00000121435.2
predicted gene 12216
chr2_-_51862941 0.78 ENSMUST00000145481.8
ENSMUST00000112705.9
N-myc (and STAT) interactor
chr2_+_11710246 0.78 ENSMUST00000148748.8
interleukin 15 receptor, alpha chain
chr7_+_100355798 0.78 ENSMUST00000107042.9
ENSMUST00000207564.2
ENSMUST00000049053.9
family with sequence similarity 168, member A
chr17_-_30845845 0.77 ENSMUST00000235547.2
ENSMUST00000188852.2
glyoxalase 1
RIKEN cDNA 1700097N02 gene
chr10_-_75633362 0.77 ENSMUST00000120177.8
glutathione S-transferase, theta 1
chr7_-_19297001 0.76 ENSMUST00000058444.10
protein phosphatase 1, regulatory subunit 37
chr17_+_25114090 0.76 ENSMUST00000043907.14
mitochondrial ribosomal protein S34
chr9_-_106353303 0.75 ENSMUST00000156426.8
poly (ADP-ribose) polymerase family, member 3
chr17_+_85264134 0.74 ENSMUST00000112305.10
protein phosphatase 1B, magnesium dependent, beta isoform
chr1_+_183766572 0.73 ENSMUST00000048655.8
dual specificity phosphatase 10
chr11_-_70350783 0.73 ENSMUST00000019064.9
chemokine (C-X-C motif) ligand 16
chr3_+_106389732 0.72 ENSMUST00000029508.11
DENN/MADD domain containing 2D
chr3_+_106628987 0.72 ENSMUST00000130105.2
ligand dependent nuclear receptor interacting factor 1
chrX_-_151820545 0.71 ENSMUST00000051484.5
MAGE family member H1
chr10_-_75633563 0.71 ENSMUST00000139724.3
glutathione S-transferase, theta 1
chr14_-_51134930 0.70 ENSMUST00000227271.2
kelch-like 33
chr9_+_54858066 0.70 ENSMUST00000034848.14
proteasome subunit alpha 4
chr11_+_48967411 0.68 ENSMUST00000109202.3
interferon gamma inducible protein 47
chr9_+_38629560 0.67 ENSMUST00000001544.12
ENSMUST00000118144.8
von Willebrand factor A domain containing 5A
chr2_-_101451383 0.67 ENSMUST00000090513.11
intraflagellar transport associated protein
chr10_-_116732813 0.65 ENSMUST00000048229.9
myelin regulatory factor-like
chr7_+_130972867 0.64 ENSMUST00000075610.13
phosphoseryl-tRNA kinase
chr5_-_93354348 0.63 ENSMUST00000058550.15
cyclin I
chr15_-_77480311 0.63 ENSMUST00000089465.6
apolipoprotein L 10B
chr8_+_93553901 0.63 ENSMUST00000034187.9
matrix metallopeptidase 2
chr16_+_35892437 0.62 ENSMUST00000163352.9
ENSMUST00000231468.2
coiled-coil domain containing 58
chr3_+_142326363 0.61 ENSMUST00000165774.8
guanylate binding protein 2
chr15_+_66763169 0.61 ENSMUST00000005255.9
cellular communication network factor 4
chrX_+_160500051 0.60 ENSMUST00000112338.2
retinoic acid induced 2
chr2_+_31462659 0.60 ENSMUST00000113482.8
far upstream element (FUSE) binding protein 3
chr17_-_36206812 0.59 ENSMUST00000059740.15
RIKEN cDNA 2310061I04 gene
chr15_+_90108480 0.59 ENSMUST00000100309.3
ENSMUST00000231200.2
asparagine-linked glycosylation 10B (alpha-1,2-glucosyltransferase)
chr19_-_6134903 0.59 ENSMUST00000160977.8
ENSMUST00000159859.2
ENSMUST00000025707.9
ENSMUST00000160712.8
ENSMUST00000237738.2
zinc finger like protein 1
chr18_+_77031788 0.59 ENSMUST00000097522.11
ENSMUST00000097521.12
ENSMUST00000145634.9
haloacid dehalogenase-like hydrolase domain containing 2
chr5_-_92582969 0.59 ENSMUST00000135112.8
nucleoporin 54
chr9_-_123461593 0.58 ENSMUST00000026273.11
solute carrier family 6 (neurotransmitter transporter), member 20B
chr9_+_54858092 0.58 ENSMUST00000172407.8
proteasome subunit alpha 4
chr14_-_51134906 0.58 ENSMUST00000170855.2
kelch-like 33
chr7_-_18852282 0.58 ENSMUST00000141380.3
meiosis initiator
chr14_-_55909314 0.57 ENSMUST00000163750.8
neural precursor cell expressed, developmentally down-regulated gene 8
chr1_+_85177316 0.57 ENSMUST00000161424.5
ENSMUST00000113402.4
predicted pseudogene 7609
chr2_+_65499097 0.57 ENSMUST00000200829.4
sodium channel, voltage-gated, type II, alpha
chr15_-_89263466 0.56 ENSMUST00000228111.2
outer dense fiber of sperm tails 3B
chr3_-_88332401 0.56 ENSMUST00000168755.7
ENSMUST00000193433.6
ENSMUST00000195657.6
ENSMUST00000057935.9
solute carrier family 25, member 44
chr11_+_119158713 0.56 ENSMUST00000106259.9
glucosidase, alpha, acid
chr2_+_11710633 0.56 ENSMUST00000114832.3
interleukin 15 receptor, alpha chain
chr2_-_51863203 0.55 ENSMUST00000028314.9
N-myc (and STAT) interactor
chr8_-_11528615 0.54 ENSMUST00000033900.7
RAB20, member RAS oncogene family
chr8_+_47192767 0.54 ENSMUST00000034041.9
ENSMUST00000208507.2
ENSMUST00000207105.2
interferon regulatory factor 2
chr16_+_43184191 0.54 ENSMUST00000156367.8
zinc finger and BTB domain containing 20
chr17_+_31514780 0.54 ENSMUST00000237460.2
solute carrier family 37 (glycerol-3-phosphate transporter), member 1
chr16_+_10307589 0.53 ENSMUST00000230892.2
ENSMUST00000230146.2
ENSMUST00000230392.2
class II transactivator
chr17_-_26004507 0.53 ENSMUST00000140738.8
ENSMUST00000145053.2
ENSMUST00000138759.8
ENSMUST00000133071.8
ENSMUST00000077938.10
hydroxyacylglutathione hydrolase-like
chr2_-_90735171 0.53 ENSMUST00000005647.4
NADH:ubiquinone oxidoreductase core subunit S3
chr6_-_125208738 0.51 ENSMUST00000043422.8
TAP binding protein-like
chr5_+_28370687 0.50 ENSMUST00000036177.9
engrailed 2
chr14_+_55909692 0.50 ENSMUST00000002397.7
guanosine monophosphate reductase 2
chr16_-_38253507 0.50 ENSMUST00000002926.8
phospholipase A1 member A
chr5_-_93354287 0.50 ENSMUST00000144514.3
cyclin I
chr3_-_115800989 0.49 ENSMUST00000067485.4
solute carrier family 30 (zinc transporter), member 7
chr9_+_44394080 0.49 ENSMUST00000220303.2
B cell CLL/lymphoma 9-like
chr14_-_30850881 0.49 ENSMUST00000203261.3
small integral membrane protein 4
chr17_-_37334091 0.49 ENSMUST00000167275.3
myelin oligodendrocyte glycoprotein
chr7_+_29883569 0.49 ENSMUST00000098594.4
cytochrome c oxidase subunit 7A1
chr8_-_84059048 0.48 ENSMUST00000177594.8
ENSMUST00000053902.4
ELMO/CED-12 domain containing 2
chr11_+_119158829 0.47 ENSMUST00000026666.13
ENSMUST00000106258.2
glucosidase, alpha, acid
chr10_-_29411857 0.47 ENSMUST00000092623.5
R-spondin 3
chr11_-_98478018 0.46 ENSMUST00000052919.8
ORM1-like 3 (S. cerevisiae)
chr13_+_22017906 0.46 ENSMUST00000180288.2
H2B clustered histone 24
chr17_-_32253467 0.46 ENSMUST00000002145.12
ENSMUST00000133308.3
heat shock transcription factor 2 binding protein
chr5_-_127709961 0.46 ENSMUST00000155321.2
solute carrier family 15, member 4
chr8_-_45863572 0.46 ENSMUST00000209651.2
ENSMUST00000211370.2
ENSMUST00000034056.12
ENSMUST00000167106.3
toll-like receptor 3
chr12_+_8258107 0.45 ENSMUST00000037383.13
ENSMUST00000218883.2
ENSMUST00000218086.2
ENSMUST00000169104.3
ENSMUST00000217999.2
lipid droplet associated hydrolase
chr16_+_97337275 0.45 ENSMUST00000024112.8
MX dynamin-like GTPase 2
chr7_-_7212997 0.45 ENSMUST00000074455.9
zinc finger protein 772
chr2_+_97298002 0.44 ENSMUST00000059049.8
leucine rich repeat containing 4C
chr4_+_123077515 0.43 ENSMUST00000152194.2
hippocalcin-like 4
chr1_+_180978491 0.43 ENSMUST00000134115.8
ENSMUST00000111059.2
cornichon family AMPA receptor auxiliary protein 4
chr12_+_71021395 0.43 ENSMUST00000160027.8
ENSMUST00000160864.8
proteasome subunit alpha 3
chr1_+_85454323 0.43 ENSMUST00000239236.2
predicted gene 7592
chr16_-_18882012 0.42 ENSMUST00000199490.2
immunoglobulin lambda joining 1
chr7_+_29883611 0.42 ENSMUST00000208441.2
cytochrome c oxidase subunit 7A1
chr6_-_8180174 0.42 ENSMUST00000213284.2
collagen, type XXVIII, alpha 1
chr18_-_66155651 0.41 ENSMUST00000143990.2
lectin, mannose-binding, 1

Network of associatons between targets according to the STRING database.

First level regulatory network of Prdm1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
3.2 9.6 GO:0009087 methionine catabolic process(GO:0009087)
2.1 8.6 GO:0034285 response to sucrose(GO:0009744) response to disaccharide(GO:0034285)
1.6 4.7 GO:2000547 regulation of dendritic cell dendrite assembly(GO:2000547)
1.3 4.0 GO:0019442 tryptophan catabolic process to acetyl-CoA(GO:0019442)
1.3 3.9 GO:2000487 asparagine transport(GO:0006867) positive regulation of glutamine transport(GO:2000487)
1.0 6.0 GO:1990166 protein localization to site of double-strand break(GO:1990166)
0.7 8.6 GO:0043651 linoleic acid metabolic process(GO:0043651)
0.7 2.1 GO:0042732 D-xylose metabolic process(GO:0042732)
0.7 4.1 GO:0061760 antifungal innate immune response(GO:0061760)
0.7 2.7 GO:0032382 positive regulation of intracellular lipid transport(GO:0032379) positive regulation of intracellular sterol transport(GO:0032382) positive regulation of intracellular cholesterol transport(GO:0032385) lipid hydroperoxide transport(GO:1901373)
0.7 3.3 GO:0009732 detection of carbohydrate stimulus(GO:0009730) detection of hexose stimulus(GO:0009732) detection of monosaccharide stimulus(GO:0034287) detection of glucose(GO:0051594)
0.6 2.5 GO:1903237 negative regulation of leukocyte tethering or rolling(GO:1903237)
0.6 2.5 GO:0050823 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent(GO:0002479) peptide stabilization(GO:0050822) peptide antigen stabilization(GO:0050823)
0.5 0.5 GO:0002590 regulation of antigen processing and presentation of peptide antigen via MHC class I(GO:0002589) negative regulation of antigen processing and presentation of peptide antigen via MHC class I(GO:0002590)
0.5 1.5 GO:0018900 dichloromethane metabolic process(GO:0018900)
0.5 1.4 GO:0006553 lysine metabolic process(GO:0006553)
0.4 1.3 GO:1902524 positive regulation of protein K48-linked ubiquitination(GO:1902524)
0.4 2.9 GO:0045716 positive regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045716)
0.4 4.6 GO:0046485 ether lipid metabolic process(GO:0046485)
0.3 2.4 GO:0006083 acetate metabolic process(GO:0006083)
0.3 1.0 GO:0035928 rRNA import into mitochondrion(GO:0035928)
0.3 1.0 GO:0043181 vacuolar sequestering(GO:0043181)
0.3 1.7 GO:0018916 nitrobenzene metabolic process(GO:0018916)
0.3 2.9 GO:0061709 reticulophagy(GO:0061709)
0.3 1.9 GO:0000270 peptidoglycan metabolic process(GO:0000270) peptidoglycan catabolic process(GO:0009253) negative regulation of natural killer cell differentiation(GO:0032824) negative regulation of natural killer cell differentiation involved in immune response(GO:0032827)
0.3 1.9 GO:0003383 apical constriction(GO:0003383)
0.3 0.8 GO:1902623 negative regulation of neutrophil migration(GO:1902623)
0.3 1.3 GO:1903416 response to glycoside(GO:1903416)
0.3 2.1 GO:1990504 dense core granule exocytosis(GO:1990504)
0.3 1.3 GO:0042270 protection from natural killer cell mediated cytotoxicity(GO:0042270)
0.3 1.0 GO:0070212 protein poly-ADP-ribosylation(GO:0070212)
0.3 2.1 GO:0033762 response to glucagon(GO:0033762)
0.3 4.3 GO:0006590 thyroid hormone generation(GO:0006590)
0.2 5.1 GO:0021684 cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.2 1.2 GO:1990592 protein polyufmylation(GO:1990564) protein K69-linked ufmylation(GO:1990592)
0.2 0.9 GO:0036228 protein targeting to nuclear inner membrane(GO:0036228)
0.2 2.8 GO:0070189 kynurenine metabolic process(GO:0070189)
0.2 1.4 GO:0002317 plasma cell differentiation(GO:0002317)
0.2 1.0 GO:0097343 ripoptosome assembly(GO:0097343) ripoptosome assembly involved in necroptotic process(GO:1901026)
0.2 0.8 GO:1905053 regulation of base-excision repair(GO:1905051) positive regulation of base-excision repair(GO:1905053)
0.2 1.7 GO:0018401 peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401)
0.2 1.9 GO:0019885 antigen processing and presentation of endogenous peptide antigen via MHC class I(GO:0019885)
0.2 0.5 GO:0046038 GMP catabolic process(GO:0046038)
0.2 0.9 GO:0060335 positive regulation of response to interferon-gamma(GO:0060332) positive regulation of interferon-gamma-mediated signaling pathway(GO:0060335)
0.2 0.5 GO:0015817 histidine transport(GO:0015817)
0.1 2.2 GO:0015747 urate transport(GO:0015747)
0.1 0.8 GO:0045354 interferon-alpha biosynthetic process(GO:0045349) regulation of interferon-alpha biosynthetic process(GO:0045354)
0.1 1.0 GO:0016259 selenocysteine metabolic process(GO:0016259)
0.1 1.3 GO:0019243 methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione(GO:0019243) methylglyoxal catabolic process(GO:0051596) methylglyoxal catabolic process to lactate(GO:0061727)
0.1 0.6 GO:0014012 peripheral nervous system axon regeneration(GO:0014012)
0.1 0.7 GO:0060266 negative regulation of respiratory burst involved in inflammatory response(GO:0060266)
0.1 1.5 GO:0006527 arginine catabolic process(GO:0006527)
0.1 0.3 GO:0090071 negative regulation of ribosome biogenesis(GO:0090071)
0.1 0.5 GO:1900060 negative regulation of ceramide biosynthetic process(GO:1900060)
0.1 0.3 GO:0042138 meiotic DNA double-strand break formation(GO:0042138)
0.1 2.8 GO:0032825 positive regulation of natural killer cell differentiation(GO:0032825)
0.1 0.7 GO:0006499 N-terminal protein myristoylation(GO:0006499)
0.1 0.4 GO:0000966 RNA 5'-end processing(GO:0000966) mitochondrial tRNA processing(GO:0090646)
0.1 1.2 GO:0070842 aggresome assembly(GO:0070842)
0.1 0.4 GO:0090156 lysosomal microautophagy(GO:0016237) piecemeal microautophagy of nucleus(GO:0034727) suppression by virus of host autophagy(GO:0039521) amino acid homeostasis(GO:0080144) negative regulation of sphingolipid biosynthetic process(GO:0090155) cellular sphingolipid homeostasis(GO:0090156) negative regulation of sphingolipid biosynthesis involved in cellular sphingolipid homeostasis(GO:0090157)
0.1 0.5 GO:0090383 phagosome acidification(GO:0090383)
0.1 1.2 GO:0048280 vesicle fusion with Golgi apparatus(GO:0048280)
0.1 0.8 GO:0015760 hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.1 1.4 GO:0006977 DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest(GO:0006977)
0.1 0.8 GO:1900194 negative regulation of oocyte maturation(GO:1900194)
0.1 0.4 GO:0051581 negative regulation of neurotransmitter uptake(GO:0051581) negative regulation of serotonin uptake(GO:0051612)
0.1 0.3 GO:2000836 positive regulation of androgen secretion(GO:2000836)
0.1 0.6 GO:0001514 selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)
0.1 0.3 GO:0002121 inter-male aggressive behavior(GO:0002121)
0.1 0.3 GO:0010636 positive regulation of mitochondrial fusion(GO:0010636)
0.1 1.0 GO:0006614 SRP-dependent cotranslational protein targeting to membrane(GO:0006614)
0.1 0.5 GO:0045343 MHC class I biosynthetic process(GO:0045341) regulation of MHC class I biosynthetic process(GO:0045343) positive regulation of MHC class I biosynthetic process(GO:0045345)
0.1 0.4 GO:0042985 negative regulation of amyloid precursor protein biosynthetic process(GO:0042985)
0.1 1.5 GO:0006516 glycoprotein catabolic process(GO:0006516)
0.1 0.2 GO:1904430 negative regulation of t-circle formation(GO:1904430)
0.1 0.2 GO:0002182 cytoplasmic translational elongation(GO:0002182) regulation of cytoplasmic translational elongation(GO:1900247) negative regulation of cytoplasmic translational elongation(GO:1900248)
0.1 1.6 GO:0045116 protein neddylation(GO:0045116)
0.1 0.6 GO:0008627 intrinsic apoptotic signaling pathway in response to osmotic stress(GO:0008627)
0.1 1.2 GO:0046519 sphingoid metabolic process(GO:0046519)
0.0 2.0 GO:0050892 intestinal absorption(GO:0050892)
0.0 0.3 GO:0019364 pyridine nucleotide catabolic process(GO:0019364)
0.0 0.5 GO:0014029 neural crest formation(GO:0014029)
0.0 0.3 GO:0007341 penetration of zona pellucida(GO:0007341)
0.0 0.4 GO:0010700 negative regulation of norepinephrine secretion(GO:0010700)
0.0 0.8 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.0 3.0 GO:0071346 cellular response to interferon-gamma(GO:0071346)
0.0 8.0 GO:0009308 amine metabolic process(GO:0009308)
0.0 0.4 GO:0006561 proline biosynthetic process(GO:0006561)
0.0 0.3 GO:0035694 mitochondrial protein catabolic process(GO:0035694)
0.0 0.3 GO:0010701 positive regulation of norepinephrine secretion(GO:0010701)
0.0 0.4 GO:0072602 interleukin-4 secretion(GO:0072602)
0.0 0.2 GO:1904784 NLRP1 inflammasome complex assembly(GO:1904784)
0.0 0.3 GO:0007039 protein catabolic process in the vacuole(GO:0007039)
0.0 0.6 GO:0006488 dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.0 0.3 GO:0072619 interleukin-21 production(GO:0032625) interleukin-21 secretion(GO:0072619)
0.0 4.4 GO:0019395 fatty acid oxidation(GO:0019395)
0.0 0.5 GO:0061088 sequestering of zinc ion(GO:0032119) regulation of sequestering of zinc ion(GO:0061088)
0.0 0.3 GO:0045198 establishment of epithelial cell apical/basal polarity(GO:0045198)
0.0 0.3 GO:0048251 elastic fiber assembly(GO:0048251)
0.0 0.6 GO:1990403 embryonic brain development(GO:1990403)
0.0 0.2 GO:0070268 cornification(GO:0070268)
0.0 0.7 GO:0010818 T cell chemotaxis(GO:0010818)
0.0 0.2 GO:0071492 cellular response to UV-A(GO:0071492)
0.0 0.2 GO:0051771 negative regulation of nitric-oxide synthase biosynthetic process(GO:0051771)
0.0 0.6 GO:0002360 T cell lineage commitment(GO:0002360)
0.0 0.4 GO:0031573 intra-S DNA damage checkpoint(GO:0031573)
0.0 0.5 GO:0060670 branching involved in labyrinthine layer morphogenesis(GO:0060670)
0.0 3.6 GO:0016052 carbohydrate catabolic process(GO:0016052)
0.0 0.3 GO:0070102 interleukin-6-mediated signaling pathway(GO:0070102)
0.0 0.2 GO:0018026 peptidyl-lysine monomethylation(GO:0018026)
0.0 0.2 GO:0035457 cellular response to interferon-alpha(GO:0035457)
0.0 0.7 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.0 0.1 GO:0015755 fructose transport(GO:0015755)
0.0 0.1 GO:0015722 canalicular bile acid transport(GO:0015722)
0.0 0.1 GO:0002838 T cell mediated immune response to tumor cell(GO:0002424) negative regulation of response to tumor cell(GO:0002835) negative regulation of immune response to tumor cell(GO:0002838) regulation of T cell mediated immune response to tumor cell(GO:0002840)
0.0 0.1 GO:1902748 positive regulation of lens fiber cell differentiation(GO:1902748)
0.0 0.1 GO:0036337 Fas signaling pathway(GO:0036337)
0.0 0.2 GO:0061303 cornea development in camera-type eye(GO:0061303)
0.0 0.3 GO:0043383 negative T cell selection(GO:0043383)
0.0 0.5 GO:0090077 foam cell differentiation(GO:0090077)
0.0 0.3 GO:0035634 response to stilbenoid(GO:0035634)
0.0 0.1 GO:0051490 negative regulation of filopodium assembly(GO:0051490)
0.0 1.6 GO:0048041 cell-substrate adherens junction assembly(GO:0007045) focal adhesion assembly(GO:0048041)
0.0 0.1 GO:0045065 cytotoxic T cell differentiation(GO:0045065)
0.0 1.0 GO:0021766 hippocampus development(GO:0021766)
0.0 0.2 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.0 0.8 GO:0032543 mitochondrial translation(GO:0032543)
0.0 1.2 GO:0006888 ER to Golgi vesicle-mediated transport(GO:0006888)
0.0 1.7 GO:0048814 regulation of dendrite morphogenesis(GO:0048814)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 2.2 GO:1990111 spermatoproteasome complex(GO:1990111)
0.3 1.7 GO:0016222 procollagen-proline 4-dioxygenase complex(GO:0016222)
0.3 2.5 GO:0042825 TAP complex(GO:0042825)
0.2 1.9 GO:0033269 internode region of axon(GO:0033269)
0.2 2.0 GO:0045179 apical cortex(GO:0045179)
0.2 2.2 GO:0031315 extrinsic component of mitochondrial outer membrane(GO:0031315)
0.2 3.3 GO:0045180 basal cortex(GO:0045180)
0.2 0.5 GO:1902560 GMP reductase complex(GO:1902560)
0.2 1.7 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.1 1.3 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.1 6.0 GO:0035861 site of double-strand break(GO:0035861)
0.1 1.5 GO:0044322 endoplasmic reticulum quality control compartment(GO:0044322)
0.1 0.5 GO:0035339 SPOTS complex(GO:0035339)
0.1 1.0 GO:0097542 ciliary tip(GO:0097542)
0.1 0.9 GO:0044613 nuclear pore central transport channel(GO:0044613)
0.1 3.0 GO:0033270 paranode region of axon(GO:0033270)
0.1 0.4 GO:0048476 Holliday junction resolvase complex(GO:0048476)
0.1 0.2 GO:0043564 Ku70:Ku80 complex(GO:0043564)
0.1 1.0 GO:0033655 host cell cytoplasm(GO:0030430) host cell cytoplasm part(GO:0033655)
0.0 1.2 GO:0012507 ER to Golgi transport vesicle membrane(GO:0012507)
0.0 0.6 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.0 2.7 GO:0005811 lipid particle(GO:0005811)
0.0 1.4 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.0 5.9 GO:0016363 nuclear matrix(GO:0016363)
0.0 2.9 GO:0005801 cis-Golgi network(GO:0005801)
0.0 1.7 GO:0030660 Golgi-associated vesicle membrane(GO:0030660)
0.0 0.1 GO:0046691 intracellular canaliculus(GO:0046691)
0.0 0.3 GO:0000788 nuclear nucleosome(GO:0000788)
0.0 2.1 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.0 0.2 GO:0072558 NLRP1 inflammasome complex(GO:0072558)
0.0 1.4 GO:0030964 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 0.9 GO:0005746 mitochondrial respiratory chain(GO:0005746)
0.0 1.6 GO:0031941 filamentous actin(GO:0031941)
0.0 0.7 GO:0031233 intrinsic component of external side of plasma membrane(GO:0031233)
0.0 0.3 GO:0043205 microfibril(GO:0001527) fibril(GO:0043205)
0.0 2.1 GO:0042734 presynaptic membrane(GO:0042734)
0.0 0.9 GO:0016235 aggresome(GO:0016235)
0.0 1.1 GO:0000315 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0 1.1 GO:0045171 intercellular bridge(GO:0045171)
0.0 1.3 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 0.4 GO:0000314 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.0 0.1 GO:0030134 ER to Golgi transport vesicle(GO:0030134)
0.0 0.4 GO:0000407 pre-autophagosomal structure(GO:0000407)
0.0 23.0 GO:0005783 endoplasmic reticulum(GO:0005783)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
2.9 8.6 GO:0004454 ketohexokinase activity(GO:0004454)
2.4 9.6 GO:0004478 methionine adenosyltransferase activity(GO:0004478)
2.1 8.6 GO:0071614 linoleic acid epoxygenase activity(GO:0071614)
1.5 4.6 GO:0050479 glyceryl-ether monooxygenase activity(GO:0050479)
1.0 8.0 GO:0008172 S-methyltransferase activity(GO:0008172)
1.0 4.0 GO:0016823 hydrolase activity, acting on acid carbon-carbon bonds(GO:0016822) hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances(GO:0016823)
1.0 3.9 GO:0015182 L-asparagine transmembrane transporter activity(GO:0015182)
0.8 2.4 GO:0019807 aspartoacylase activity(GO:0019807)
0.7 2.1 GO:0004967 glucagon receptor activity(GO:0004967)
0.7 2.7 GO:0050632 propanoyl-CoA C-acyltransferase activity(GO:0033814) propionyl-CoA C2-trimethyltridecanoyltransferase activity(GO:0050632) phosphatidylethanolamine transporter activity(GO:1904121)
0.6 2.4 GO:0031735 CCR10 chemokine receptor binding(GO:0031735)
0.6 4.3 GO:0070573 metallodipeptidase activity(GO:0070573)
0.6 6.0 GO:0003910 DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910)
0.6 2.8 GO:0047804 cysteine-S-conjugate beta-lyase activity(GO:0047804)
0.5 3.6 GO:0004556 alpha-amylase activity(GO:0004556)
0.5 1.5 GO:0019120 hydrolase activity, acting on acid halide bonds(GO:0016824) hydrolase activity, acting on acid halide bonds, in C-halide compounds(GO:0019120) alkylhalidase activity(GO:0047651)
0.4 0.8 GO:0016160 amylase activity(GO:0016160)
0.4 2.5 GO:0046979 TAP1 binding(GO:0046978) TAP2 binding(GO:0046979)
0.3 3.3 GO:0004340 glucokinase activity(GO:0004340) hexokinase activity(GO:0004396)
0.3 1.0 GO:0070279 vitamin B6 binding(GO:0070279)
0.3 1.9 GO:0008745 N-acetylmuramoyl-L-alanine amidase activity(GO:0008745) peptidoglycan receptor activity(GO:0016019)
0.3 1.7 GO:0004656 procollagen-proline 4-dioxygenase activity(GO:0004656)
0.3 2.2 GO:0015562 efflux transmembrane transporter activity(GO:0015562)
0.3 1.0 GO:0004574 oligo-1,6-glucosidase activity(GO:0004574) maltose alpha-glucosidase activity(GO:0032450)
0.2 1.4 GO:0016647 oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor(GO:0016647)
0.2 0.5 GO:0005290 L-histidine transmembrane transporter activity(GO:0005290)
0.2 2.0 GO:0005324 long-chain fatty acid transporter activity(GO:0005324)
0.2 2.5 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.2 1.9 GO:0005138 interleukin-6 receptor binding(GO:0005138)
0.2 0.5 GO:0016657 GMP reductase activity(GO:0003920) oxidoreductase activity, acting on NAD(P)H, nitrogenous group as acceptor(GO:0016657)
0.1 3.9 GO:0070003 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.1 4.0 GO:0008009 chemokine activity(GO:0008009)
0.1 1.5 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.1 2.7 GO:0016290 palmitoyl-CoA hydrolase activity(GO:0016290)
0.1 0.4 GO:0016426 tRNA (adenine) methyltransferase activity(GO:0016426)
0.1 1.0 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.1 0.8 GO:0015315 hexose phosphate transmembrane transporter activity(GO:0015119) organophosphate:inorganic phosphate antiporter activity(GO:0015315) hexose-phosphate:inorganic phosphate antiporter activity(GO:0015526) glucose 6-phosphate:inorganic phosphate antiporter activity(GO:0061513)
0.1 1.3 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391) steroid hormone binding(GO:1990239)
0.1 2.8 GO:0005540 hyaluronic acid binding(GO:0005540)
0.1 0.4 GO:0019779 Atg12 activating enzyme activity(GO:0019778) Atg8 activating enzyme activity(GO:0019779)
0.1 0.8 GO:0016846 carbon-sulfur lyase activity(GO:0016846)
0.1 1.0 GO:0001730 2'-5'-oligoadenylate synthetase activity(GO:0001730)
0.1 1.5 GO:1904264 ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.1 0.5 GO:0008970 phosphatidylcholine 1-acylhydrolase activity(GO:0008970)
0.1 1.9 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.1 3.4 GO:0016655 oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor(GO:0016655)
0.1 0.4 GO:0004735 pyrroline-5-carboxylate reductase activity(GO:0004735)
0.1 1.0 GO:0008097 5S rRNA binding(GO:0008097)
0.1 3.6 GO:0005044 scavenger receptor activity(GO:0005044)
0.1 0.5 GO:0004416 hydroxyacylglutathione hydrolase activity(GO:0004416)
0.1 1.4 GO:0070513 death domain binding(GO:0070513)
0.1 0.3 GO:0003829 beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0003829)
0.1 0.3 GO:0030284 estrogen receptor activity(GO:0030284)
0.1 2.5 GO:0071889 14-3-3 protein binding(GO:0071889)
0.1 1.2 GO:0070628 proteasome binding(GO:0070628)
0.0 3.7 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.0 0.6 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.0 0.7 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0 0.4 GO:0008821 crossover junction endodeoxyribonuclease activity(GO:0008821)
0.0 0.3 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.0 0.4 GO:0031730 CCR5 chemokine receptor binding(GO:0031730)
0.0 0.6 GO:0046527 glucosyltransferase activity(GO:0046527)
0.0 0.1 GO:0047936 glucose 1-dehydrogenase [NAD(P)] activity(GO:0047936)
0.0 1.7 GO:0004364 glutathione transferase activity(GO:0004364)
0.0 0.6 GO:0043522 leucine zipper domain binding(GO:0043522)
0.0 0.9 GO:0016676 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 0.4 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609)
0.0 0.2 GO:0004661 protein geranylgeranyltransferase activity(GO:0004661)
0.0 0.3 GO:0003956 NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956)
0.0 4.5 GO:0020037 heme binding(GO:0020037)
0.0 0.3 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.0 0.9 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.0 0.2 GO:0048019 receptor antagonist activity(GO:0048019)
0.0 1.1 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.0 0.2 GO:0051575 5'-deoxyribose-5-phosphate lyase activity(GO:0051575)
0.0 1.3 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0 0.1 GO:0008147 structural constituent of bone(GO:0008147)
0.0 0.2 GO:0046976 histone methyltransferase activity (H3-K27 specific)(GO:0046976)
0.0 1.8 GO:0042974 retinoic acid receptor binding(GO:0042974)
0.0 2.5 GO:0004197 cysteine-type endopeptidase activity(GO:0004197)
0.0 1.7 GO:0001540 beta-amyloid binding(GO:0001540)
0.0 0.4 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.0 0.3 GO:0003854 3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854)
0.0 1.4 GO:0015485 cholesterol binding(GO:0015485)
0.0 0.8 GO:0051059 NF-kappaB binding(GO:0051059)
0.0 0.6 GO:0001968 fibronectin binding(GO:0001968)
0.0 0.4 GO:0005537 mannose binding(GO:0005537)
0.0 2.5 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
0.0 0.3 GO:0015271 outward rectifier potassium channel activity(GO:0015271)
0.0 0.1 GO:0032184 SUMO polymer binding(GO:0032184)
0.0 0.8 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 0.2 GO:0046703 natural killer cell lectin-like receptor binding(GO:0046703)
0.0 0.8 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.0 0.1 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.0 0.2 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.0 0.8 GO:0001784 phosphotyrosine binding(GO:0001784)
0.0 0.7 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.0 0.5 GO:0071837 HMG box domain binding(GO:0071837)
0.0 0.4 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.3 GO:0046961 proton-transporting ATPase activity, rotational mechanism(GO:0046961)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.6 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.1 3.2 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.1 4.0 ST JNK MAPK PATHWAY JNK MAPK Pathway
0.1 2.4 PID SYNDECAN 2 PATHWAY Syndecan-2-mediated signaling events
0.1 2.5 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.0 1.2 PID ARF 3PATHWAY Arf1 pathway
0.0 0.8 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.0 0.8 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway
0.0 1.0 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway
0.0 6.5 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 1.1 PID HIV NEF PATHWAY HIV-1 Nef: Negative effector of Fas and TNF-alpha
0.0 1.9 SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES Genes related to the insulin receptor pathway
0.0 1.7 ST INTEGRIN SIGNALING PATHWAY Integrin Signaling Pathway
0.0 0.1 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0 0.4 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.0 1.1 PID IL4 2PATHWAY IL4-mediated signaling events
0.0 1.0 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.0 0.7 PID P75 NTR PATHWAY p75(NTR)-mediated signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 4.0 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.3 9.6 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.2 3.2 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.2 0.8 REACTOME DIGESTION OF DIETARY CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
0.1 2.7 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 7ALPHA HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol
0.1 1.5 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.1 5.7 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.1 1.9 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.1 3.3 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.1 1.7 REACTOME HS GAG DEGRADATION Genes involved in HS-GAG degradation
0.1 2.0 REACTOME AMYLOIDS Genes involved in Amyloids
0.1 1.9 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.1 1.7 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.1 0.8 REACTOME TRAF6 MEDIATED INDUCTION OF TAK1 COMPLEX Genes involved in TRAF6 mediated induction of TAK1 complex
0.1 3.9 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.1 1.6 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 1.3 REACTOME ENOS ACTIVATION AND REGULATION Genes involved in eNOS activation and regulation
0.0 8.8 REACTOME METABOLISM OF CARBOHYDRATES Genes involved in Metabolism of carbohydrates
0.0 0.6 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 1.6 REACTOME CDK MEDIATED PHOSPHORYLATION AND REMOVAL OF CDC6 Genes involved in CDK-mediated phosphorylation and removal of Cdc6
0.0 1.3 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0 1.2 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.6 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.0 1.3 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.0 0.8 REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION Genes involved in Transport to the Golgi and subsequent modification
0.0 0.7 REACTOME NOD1 2 SIGNALING PATHWAY Genes involved in NOD1/2 Signaling Pathway
0.0 1.0 REACTOME MHC CLASS II ANTIGEN PRESENTATION Genes involved in MHC class II antigen presentation
0.0 0.5 REACTOME AMINO ACID AND OLIGOPEPTIDE SLC TRANSPORTERS Genes involved in Amino acid and oligopeptide SLC transporters
0.0 0.4 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.0 1.2 REACTOME GLUCAGON SIGNALING IN METABOLIC REGULATION Genes involved in Glucagon signaling in metabolic regulation
0.0 0.5 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.0 0.5 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.0 1.4 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.0 0.6 REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.0 0.2 REACTOME INTEGRATION OF PROVIRUS Genes involved in Integration of provirus
0.0 0.6 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.0 0.8 REACTOME INTERFERON GAMMA SIGNALING Genes involved in Interferon gamma signaling
0.0 0.6 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 0.3 REACTOME REGULATION OF INSULIN SECRETION BY GLUCAGON LIKE PEPTIDE1 Genes involved in Regulation of Insulin Secretion by Glucagon-like Peptide-1