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GSE58827: Dynamics of the Mouse Liver

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Results for Prdm4

Z-value: 0.17

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Transcription factors associated with Prdm4

Gene Symbol Gene ID Gene Info
Prdm4
ENSMUSG00000035529.11 PR domain containing 4

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Prdm4mm39_v1_chr10_-_85752932_857530020.134.5e-01Click!

Activity profile of Prdm4 motif

Sorted Z-values of Prdm4 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr10_+_126814542 0.44 ENSMUST00000105256.10
Ctdsp2
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 2
chr11_+_102495189 0.22 ENSMUST00000057893.7
Fzd2
frizzled class receptor 2
chr19_-_4213347 0.18 ENSMUST00000025749.15
Rps6kb2
ribosomal protein S6 kinase, polypeptide 2
chr12_+_113115632 0.18 ENSMUST00000006523.12
ENSMUST00000200553.2
Crip1
cysteine-rich protein 1 (intestinal)
chr5_-_144902598 0.18 ENSMUST00000110677.8
ENSMUST00000085684.11
ENSMUST00000100461.7
Smurf1
SMAD specific E3 ubiquitin protein ligase 1
chr19_-_4213284 0.18 ENSMUST00000118483.2
ENSMUST00000155303.3
Rps6kb2
ribosomal protein S6 kinase, polypeptide 2
chr1_+_74430575 0.17 ENSMUST00000027367.14
Ctdsp1
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1
chr5_-_142803405 0.14 ENSMUST00000151477.8
Tnrc18
trinucleotide repeat containing 18
chr13_-_23735822 0.09 ENSMUST00000102971.2
H4c6
H4 clustered histone 6
chr5_-_142803135 0.08 ENSMUST00000198181.2
Tnrc18
trinucleotide repeat containing 18
chr12_-_111946560 0.07 ENSMUST00000190680.2
Rd3l
retinal degeneration 3-like
chr15_-_99372575 0.05 ENSMUST00000040313.6
Bcdin3d
BCDIN3 domain containing
chr12_-_111947487 0.05 ENSMUST00000190536.2
Rd3l
retinal degeneration 3-like
chr12_-_111947536 0.04 ENSMUST00000185354.2
Rd3l
retinal degeneration 3-like
chr8_+_123920682 0.03 ENSMUST00000212409.2
Dpep1
dipeptidase 1
chr11_-_43727071 0.03 ENSMUST00000167574.2
Adra1b
adrenergic receptor, alpha 1b
chr17_+_24692858 0.03 ENSMUST00000054946.10
ENSMUST00000238986.2
ENSMUST00000164508.2
Bricd5
BRICHOS domain containing 5
chr5_-_4808026 0.02 ENSMUST00000054294.7
Fzd1
frizzled class receptor 1
chr18_+_42186713 0.00 ENSMUST00000072008.11
Sh3rf2
SH3 domain containing ring finger 2
chr18_-_62748811 0.00 ENSMUST00000235190.2
Spink13
serine peptidase inhibitor, Kazal type 13

Network of associatons between targets according to the STRING database.

First level regulatory network of Prdm4

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0071211 protein targeting to vacuole involved in autophagy(GO:0071211)
0.0 0.2 GO:0007223 Wnt signaling pathway, calcium modulating pathway(GO:0007223)
0.0 0.4 GO:0045948 positive regulation of translational initiation(GO:0045948)
0.0 0.2 GO:0031507 heterochromatin assembly(GO:0031507)
0.0 0.2 GO:0071493 cellular response to UV-B(GO:0071493)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 GO:0005677 chromatin silencing complex(GO:0005677)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0004711 ribosomal protein S6 kinase activity(GO:0004711)
0.1 0.6 GO:0008420 CTD phosphatase activity(GO:0008420)
0.0 0.2 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.2 GO:0008301 DNA binding, bending(GO:0008301)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.6 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling