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GSE58827: Dynamics of the Mouse Liver

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Results for Rbpj

Z-value: 0.87

Motif logo

Transcription factors associated with Rbpj

Gene Symbol Gene ID Gene Info
ENSMUSG00000039191.13 recombination signal binding protein for immunoglobulin kappa J region

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Rbpjmm39_v1_chr5_+_53623458_536234940.803.4e-09Click!

Activity profile of Rbpj motif

Sorted Z-values of Rbpj motif

Promoter Log-likelihood Transcript Gene Gene Info
chr1_-_132318039 6.33 ENSMUST00000132435.2
transmembrane and coiled-coil domains 2
chr6_+_30639217 6.14 ENSMUST00000031806.10
carboxypeptidase A1, pancreatic
chr17_+_37180437 5.80 ENSMUST00000060524.11
tripartite motif-containing 10
chr7_+_121758646 5.74 ENSMUST00000033154.8
ENSMUST00000205901.2
polo like kinase 1
chr6_+_29694181 5.20 ENSMUST00000046750.14
ENSMUST00000115250.4
tetraspanin 33
chr14_-_70864448 4.90 ENSMUST00000110984.4
dematin actin binding protein
chr9_+_96140781 4.14 ENSMUST00000190104.7
ENSMUST00000179416.8
ENSMUST00000189606.7
transcription factor Dp 2
chr14_-_20319242 4.01 ENSMUST00000024155.9
potassium channel, subfamily K, member 16
chr18_+_34758062 3.72 ENSMUST00000166044.3
kinesin family member 20A
chr7_+_28240262 3.66 ENSMUST00000119180.4
syncollin
chr11_-_69838971 3.44 ENSMUST00000179298.3
ENSMUST00000018710.13
ENSMUST00000135437.3
ENSMUST00000141837.9
ENSMUST00000142500.8
solute carrier family 2 (facilitated glucose transporter), member 4
chr18_+_34757687 3.31 ENSMUST00000237407.2
kinesin family member 20A
chr5_-_138170644 3.31 ENSMUST00000000505.16
minichromosome maintenance complex component 7
chr18_+_34757666 3.11 ENSMUST00000167161.9
kinesin family member 20A
chr5_-_138170077 3.11 ENSMUST00000155902.8
ENSMUST00000148879.8
minichromosome maintenance complex component 7
chr14_-_70864666 2.98 ENSMUST00000022694.17
dematin actin binding protein
chr2_+_148640705 2.62 ENSMUST00000028931.10
ENSMUST00000109947.2
cystatin 8 (cystatin-related epididymal spermatogenic)
chr3_-_103716593 2.59 ENSMUST00000063502.13
ENSMUST00000106832.2
ENSMUST00000106834.8
ENSMUST00000029435.15
DNA cross-link repair 1B
chr4_-_126096376 2.51 ENSMUST00000106142.8
ENSMUST00000169403.8
ENSMUST00000130334.2
thyroid hormone receptor associated protein 3
chr14_+_75368532 2.26 ENSMUST00000143539.8
ENSMUST00000134114.8
lymphocyte cytosolic protein 1
chr19_+_53128901 2.22 ENSMUST00000235754.2
ENSMUST00000237301.2
ENSMUST00000238130.2
adducin 3 (gamma)
chr9_+_44245981 1.99 ENSMUST00000052686.4
H2A.X variant histone
chr16_+_18247666 1.88 ENSMUST00000144233.3
thioredoxin reductase 2
chr9_+_106699073 1.82 ENSMUST00000159645.8
DDB1 and CUL4 associated factor 1
chr8_-_89362745 1.76 ENSMUST00000034087.9
sorting nexin 20
chr1_+_74193138 1.76 ENSMUST00000027372.8
ENSMUST00000106899.4
chemokine (C-X-C motif) receptor 2
chr7_+_29683373 1.75 ENSMUST00000148442.8
zinc finger protein 568
chr10_-_93725472 1.72 ENSMUST00000180375.8
methionine aminopeptidase 2
chr19_+_46044972 1.71 ENSMUST00000111899.8
ENSMUST00000099392.10
ENSMUST00000062322.11
peroxisome proliferative activated receptor, gamma, coactivator-related 1
chrX_-_73009933 1.64 ENSMUST00000114372.3
ENSMUST00000033761.13
host cell factor C1
chr11_-_80670815 1.63 ENSMUST00000041065.14
ENSMUST00000070997.6
myosin ID
chr12_-_80306865 1.62 ENSMUST00000167327.2
actinin, alpha 1
chr19_+_8944369 1.58 ENSMUST00000052248.8
eukaryotic translation elongation factor 1 gamma
chr8_+_71047110 1.54 ENSMUST00000019283.10
ENSMUST00000210005.2
myo-inositol 1-phosphate synthase A1
chr11_+_63023893 1.49 ENSMUST00000108700.2
peripheral myelin protein 22
chr7_-_119058489 1.48 ENSMUST00000207887.3
ENSMUST00000239424.2
ENSMUST00000033255.8
glycoprotein 2 (zymogen granule membrane)
chr19_-_10554726 1.46 ENSMUST00000025568.3
transmembrane protein 138
chrX_-_36349055 1.44 ENSMUST00000115231.4
ribosomal protein L39
chr7_-_6699422 1.44 ENSMUST00000122432.4
ENSMUST00000002336.16
zinc finger, imprinted 1
chr18_-_34757653 1.43 ENSMUST00000003876.10
ENSMUST00000115766.8
ENSMUST00000097626.10
ENSMUST00000115765.2
bromodomain containing 8
chr14_+_75368939 1.42 ENSMUST00000125833.8
ENSMUST00000124499.8
lymphocyte cytosolic protein 1
chr9_+_64718596 1.37 ENSMUST00000038890.6
DENN/MADD domain containing 4A
chr2_+_164587948 1.33 ENSMUST00000109327.4
deoxynucleotidyltransferase, terminal, interacting protein 1
chr13_+_12410240 1.29 ENSMUST00000059270.10
HEAT repeat containing 1
chr7_-_99770653 1.29 ENSMUST00000208670.2
ENSMUST00000032969.14
polymerase (DNA-directed), delta 3, accessory subunit
chr19_-_10554417 1.27 ENSMUST00000236099.2
transmembrane protein 138
chr19_+_53128861 1.25 ENSMUST00000111741.10
adducin 3 (gamma)
chr19_-_10554462 1.20 ENSMUST00000236185.2
transmembrane protein 138
chrX_+_41238193 1.15 ENSMUST00000115073.9
ENSMUST00000115072.8
stromal antigen 2
chr7_+_113113061 1.13 ENSMUST00000129087.8
ENSMUST00000067929.15
ENSMUST00000164745.8
ENSMUST00000136158.8
fatty acyl CoA reductase 1
chr7_-_99770280 1.11 ENSMUST00000208184.2
polymerase (DNA-directed), delta 3, accessory subunit
chr17_-_32491339 1.05 ENSMUST00000237008.2
bromodomain containing 4
chr11_+_63023395 1.03 ENSMUST00000108701.8
peripheral myelin protein 22
chr7_+_127566629 1.01 ENSMUST00000106251.10
ENSMUST00000077609.12
ENSMUST00000121616.9
fused in sarcoma
chr12_-_80307110 0.98 ENSMUST00000021554.16
actinin, alpha 1
chr2_+_164587901 0.98 ENSMUST00000017443.14
ENSMUST00000109326.10
deoxynucleotidyltransferase, terminal, interacting protein 1
chr8_+_111448092 0.96 ENSMUST00000052457.15
MTSS I-BAR domain containing 2
chr16_+_21828515 0.95 ENSMUST00000231632.2
ENSMUST00000232534.2
SUMO/sentrin specific peptidase 2
chr5_+_3593811 0.94 ENSMUST00000197082.5
ENSMUST00000115527.8
family with sequence similarity 133, member B
chr5_+_136023649 0.92 ENSMUST00000111142.9
ENSMUST00000111145.10
ENSMUST00000111144.8
ENSMUST00000199239.5
ENSMUST00000005072.10
ENSMUST00000130345.2
deltex 2, E3 ubiquitin ligase
chr2_-_164587836 0.92 ENSMUST00000109328.8
WAP four-disulfide core domain 3
chr7_+_127376550 0.91 ENSMUST00000126761.8
ENSMUST00000047157.13
SET domain containing 1A
chr12_+_31315270 0.91 ENSMUST00000002979.16
ENSMUST00000239496.2
ENSMUST00000170495.3
laminin B1
chr2_+_154455217 0.88 ENSMUST00000081926.13
ENSMUST00000109702.2
zinc finger protein 341
chr2_+_109111083 0.87 ENSMUST00000028527.8
kinesin family member 18A
chr2_+_154390808 0.87 ENSMUST00000045116.11
ENSMUST00000109709.4
RIKEN cDNA 1700003F12 gene
chr4_-_126096551 0.86 ENSMUST00000080919.12
thyroid hormone receptor associated protein 3
chr16_-_17540685 0.86 ENSMUST00000232163.2
ENSMUST00000232202.2
ENSMUST00000080936.14
ENSMUST00000232645.2
ENSMUST00000232431.2
mediator complex subunit 15
chr4_-_149251149 0.82 ENSMUST00000084124.7
phosphogluconate dehydrogenase
chr1_+_150268544 0.81 ENSMUST00000124973.9
translocated promoter region, nuclear basket protein
chr9_+_64718708 0.76 ENSMUST00000213926.2
DENN/MADD domain containing 4A
chr19_-_38031774 0.74 ENSMUST00000226068.2
myoferlin
chr1_-_191307648 0.68 ENSMUST00000027933.11
denticleless E3 ubiquitin protein ligase
chr15_-_54935535 0.68 ENSMUST00000041733.9
TATA-box binding protein associated factor 2
chr19_+_10554799 0.66 ENSMUST00000237564.2
ENSMUST00000236743.2
ENSMUST00000235271.2
ENSMUST00000168445.2
ENSMUST00000237641.2
ENSMUST00000236352.2
cytochrome b561 family, member A3
chr16_+_21828223 0.65 ENSMUST00000023561.8
SUMO/sentrin specific peptidase 2
chr12_-_112640378 0.65 ENSMUST00000130342.2
thymoma viral proto-oncogene 1
chr19_-_46958001 0.63 ENSMUST00000235234.2
5'-nucleotidase, cytosolic II
chr12_+_31315227 0.63 ENSMUST00000169088.8
laminin B1
chr5_-_107873883 0.63 ENSMUST00000159263.3
growth factor independent 1 transcription repressor
chr4_-_149747644 0.62 ENSMUST00000105689.8
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta
chr7_+_44398064 0.59 ENSMUST00000165957.8
ENSMUST00000144515.9
vaccinia related kinase 3
chr19_-_4213347 0.58 ENSMUST00000025749.15
ribosomal protein S6 kinase, polypeptide 2
chr10_+_40225272 0.52 ENSMUST00000044672.11
ENSMUST00000095743.4
cyclin-dependent kinase 19
chr1_-_74002156 0.52 ENSMUST00000191367.2
tensin 1
chr19_+_10554845 0.52 ENSMUST00000237581.2
cytochrome b561 family, member A3
chr2_-_166904625 0.50 ENSMUST00000128676.2
zinc finger, NFX1-type containing 1
chr9_-_114469239 0.50 ENSMUST00000238809.2
ENSMUST00000216785.2
CCR4-NOT transcription complex, subunit 10
chr1_+_87254729 0.49 ENSMUST00000172794.8
ENSMUST00000164992.9
ENSMUST00000173173.8
GRB10 interacting GYF protein 2
chr11_+_78215026 0.47 ENSMUST00000102478.4
aldolase C, fructose-bisphosphate
chr4_-_117772163 0.43 ENSMUST00000036156.6
importin 13
chr1_+_150269001 0.42 ENSMUST00000119161.9
translocated promoter region, nuclear basket protein
chr13_-_67632333 0.42 ENSMUST00000223868.2
ENSMUST00000019572.9
zinc finger protein 874b
chr7_-_79765042 0.41 ENSMUST00000206714.2
ENSMUST00000107384.10
isocitrate dehydrogenase 2 (NADP+), mitochondrial
chr9_+_35470752 0.41 ENSMUST00000034615.10
ENSMUST00000121246.2
pseudouridine synthase 3
chr16_-_17540805 0.39 ENSMUST00000012259.9
ENSMUST00000232236.2
mediator complex subunit 15
chr19_+_10554510 0.38 ENSMUST00000237814.2
cytochrome b561 family, member A3
chr7_-_105401398 0.38 ENSMUST00000033184.6
tripeptidyl peptidase I
chr16_+_20470402 0.38 ENSMUST00000007212.9
ENSMUST00000232629.2
proteasome (prosome, macropain) 26S subunit, non-ATPase, 2
chr7_+_44398008 0.37 ENSMUST00000171821.8
vaccinia related kinase 3
chr5_-_88823049 0.37 ENSMUST00000133532.8
ENSMUST00000150438.2
G-rich RNA sequence binding factor 1
chrX_+_98179725 0.37 ENSMUST00000052839.7
ephrin B1
chr19_+_46045675 0.36 ENSMUST00000126127.8
ENSMUST00000147640.2
peroxisome proliferative activated receptor, gamma, coactivator-related 1
chr5_+_115465205 0.35 ENSMUST00000031513.14
serine and arginine-rich splicing factor 9
chr2_+_120439858 0.35 ENSMUST00000124187.8
HAUS augmin-like complex, subunit 2
chr1_+_74317709 0.32 ENSMUST00000077985.4
G protein-coupled bile acid receptor 1
chr11_-_62348599 0.32 ENSMUST00000127471.9
nuclear receptor co-repressor 1
chr2_+_112097087 0.32 ENSMUST00000110987.9
ENSMUST00000028549.14
solute carrier family 12, member 6
chr16_-_89940652 0.31 ENSMUST00000114124.9
T cell lymphoma invasion and metastasis 1
chr9_-_114469121 0.30 ENSMUST00000070117.8
CCR4-NOT transcription complex, subunit 10
chrX_-_8118541 0.30 ENSMUST00000115594.8
ENSMUST00000115595.8
ENSMUST00000033513.10
FtsJ RNA methyltransferase homolog 1 (E. coli)
chr7_+_5023552 0.29 ENSMUST00000208728.2
ENSMUST00000085427.6
coiled-coil domain containing 106
zinc finger protein 865
chr19_+_41921903 0.28 ENSMUST00000224258.2
ENSMUST00000026154.9
ENSMUST00000224896.2
zinc finger, DHHC domain containing 16
chr7_+_45289391 0.28 ENSMUST00000148532.4
MEF2 activating motif and SAP domain containing transcriptional regulator
chr8_+_120588977 0.27 ENSMUST00000034287.10
kelch-like 36
chr1_+_171386752 0.27 ENSMUST00000004829.13
CD244 molecule A
chr3_-_89177796 0.26 ENSMUST00000107460.8
ENSMUST00000029565.11
ENSMUST00000130230.2
solute carrier family 50 (sugar transporter), member 1
chr19_+_36061096 0.25 ENSMUST00000025714.9
ribonuclease P/MRP 30 subunit
chr6_-_5298455 0.25 ENSMUST00000057792.9
paraoxonase 2
chr7_+_78922947 0.23 ENSMUST00000037315.13
abhydrolase domain containing 2
chr1_+_21021889 0.23 ENSMUST00000038447.6
EF-hand domain (C-terminal) containing 1
chr8_-_22550321 0.22 ENSMUST00000006742.11
ATPase, Cu++ transporting, beta polypeptide
chr18_+_37880027 0.19 ENSMUST00000193404.2
protocadherin gamma subfamily A, 10
chr3_+_103716836 0.18 ENSMUST00000076599.8
ENSMUST00000106824.8
ENSMUST00000106823.8
ENSMUST00000047285.7
adaptor-related protein complex AP-4, beta 1
chr8_+_71047010 0.18 ENSMUST00000211117.2
myo-inositol 1-phosphate synthase A1
chr11_-_62348115 0.18 ENSMUST00000069456.11
ENSMUST00000018645.13
nuclear receptor co-repressor 1
chr15_+_83447784 0.18 ENSMUST00000047419.8
translocator protein
chr2_-_120439981 0.16 ENSMUST00000133612.2
ENSMUST00000102498.8
ENSMUST00000102499.8
leucine rich repeat containing 57
chr4_-_126861918 0.16 ENSMUST00000106108.9
zinc finger, MYM-type 4
chr2_+_26471062 0.15 ENSMUST00000238951.2
ENSMUST00000166920.10
EGF-like domain 7
chr2_-_180883813 0.14 ENSMUST00000094203.11
ENSMUST00000108831.8
helicase with zinc finger 2, transcriptional coactivator
chr14_-_54647647 0.13 ENSMUST00000228488.2
ENSMUST00000195970.5
solute carrier family 7 (cationic amino acid transporter, y+ system), member 7
chr7_+_113113037 0.13 ENSMUST00000033018.15
fatty acyl CoA reductase 1
chr7_+_111825063 0.13 ENSMUST00000050149.12
microtubule associated monooxygenase, calponin and LIM domain containing 2
chr16_+_32882882 0.13 ENSMUST00000023497.3
leishmanolysin-like (metallopeptidase M8 family)
chr12_-_115459678 0.13 ENSMUST00000103534.2
immunoglobulin heavy variable V1-63
chr8_-_105368298 0.12 ENSMUST00000093234.5
cytosolic iron-sulfur assembly component 2B
chr5_-_76139107 0.12 ENSMUST00000113516.2
kinase insert domain protein receptor
chr5_+_138185747 0.11 ENSMUST00000110934.9
canopy FGF signaling regulator 4
chr12_-_14202041 0.11 ENSMUST00000020926.8
LRAT domain containing 1
chr18_+_63111005 0.10 ENSMUST00000235372.2
ENSMUST00000237483.2
N-ethylmaleimide sensitive fusion protein attachment protein gamma
chr2_-_109111064 0.09 ENSMUST00000147770.2
methyltransferase like 15
chr14_-_49304110 0.08 ENSMUST00000162175.9
exocyst complex component 5
chr7_-_44397730 0.08 ENSMUST00000118162.8
ENSMUST00000140599.9
ENSMUST00000120798.8
zinc finger protein 473
chr7_-_24937276 0.08 ENSMUST00000071739.12
ENSMUST00000108411.2
glycogen synthase kinase 3 alpha
chr11_+_69871952 0.08 ENSMUST00000108593.8
CTD nuclear envelope phosphatase 1
chr11_+_76297969 0.07 ENSMUST00000021203.7
ENSMUST00000152183.2
translocase of inner mitochondrial membrane 22
chr7_+_44397837 0.07 ENSMUST00000002275.15
vaccinia related kinase 3
chr11_-_6576030 0.07 ENSMUST00000000394.14
ENSMUST00000189268.7
ENSMUST00000136682.8
transforming growth factor beta regulated gene 4
chr18_+_37794819 0.07 ENSMUST00000194888.2
ENSMUST00000194190.2
protocadherin gamma subfamily A, 1
chr2_+_104961228 0.07 ENSMUST00000111098.8
ENSMUST00000111099.2
Wilms tumor 1 homolog
chr16_+_44764046 0.06 ENSMUST00000164007.8
ENSMUST00000171779.8
CD200 receptor 3
chr11_+_109376432 0.06 ENSMUST00000106697.8
arylsulfatase G
chr16_+_11140779 0.06 ENSMUST00000115814.4
sorting nexin 29
chr2_+_59442378 0.06 ENSMUST00000112568.8
ENSMUST00000037526.11
tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1
chr18_+_37869950 0.05 ENSMUST00000091935.7
protocadherin gamma subfamily A, 9
chr2_+_128705829 0.05 ENSMUST00000028864.3
fibulin 7
chr8_+_95744320 0.05 ENSMUST00000051259.10
adhesion G protein-coupled receptor G3
chr11_-_69872050 0.04 ENSMUST00000108594.8
elongator acetyltransferase complex subunit 5
chr3_-_87792865 0.04 ENSMUST00000005015.10
papillary renal cell carcinoma (translocation-associated)
chr11_+_54205722 0.04 ENSMUST00000072178.11
ENSMUST00000101211.9
ENSMUST00000101213.9
ENSMUST00000064690.10
ENSMUST00000108899.8
acyl-CoA synthetase long-chain family member 6
chr2_-_120439826 0.04 ENSMUST00000102497.10
leucine rich repeat containing 57
chr12_+_33365371 0.03 ENSMUST00000154742.2
ataxin 7-like 1
chr12_+_83734919 0.03 ENSMUST00000041806.13
presenilin 1
chr7_-_29750785 0.02 ENSMUST00000207072.2
ENSMUST00000207873.2
zinc finger protein 14
chr7_-_10229249 0.02 ENSMUST00000032551.8
zinc finger protein interacting with K protein 1
chr5_-_24782465 0.02 ENSMUST00000030795.10
ATP-binding cassette, sub-family F (GCN20), member 2
chr9_-_95632387 0.01 ENSMUST00000189137.7
ENSMUST00000053785.10
transient receptor potential cation channel, subfamily C, member 1
chr2_+_83474779 0.01 ENSMUST00000081591.7
zinc finger CCCH-type containing 15

Network of associatons between targets according to the STRING database.

First level regulatory network of Rbpj

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.9 5.7 GO:0070194 synaptonemal complex disassembly(GO:0070194)
1.3 7.9 GO:0035585 calcium-mediated signaling using extracellular calcium source(GO:0035585)
0.6 2.6 GO:0031860 telomeric 3' overhang formation(GO:0031860)
0.6 1.8 GO:1990164 histone H2A phosphorylation(GO:1990164)
0.6 1.7 GO:0006021 inositol biosynthetic process(GO:0006021)
0.5 6.4 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.5 1.5 GO:0002386 immune response in mucosal-associated lymphoid tissue(GO:0002386)
0.4 10.1 GO:0000920 cell separation after cytokinesis(GO:0000920)
0.4 1.7 GO:0014022 neural plate elongation(GO:0014022) convergent extension involved in neural plate elongation(GO:0022007)
0.4 1.2 GO:0046832 RNA import into nucleus(GO:0006404) mRNA export from nucleus in response to heat stress(GO:0031990) negative regulation of nucleobase-containing compound transport(GO:0032240) negative regulation of RNA export from nucleus(GO:0046832)
0.4 1.6 GO:0019046 release from viral latency(GO:0019046)
0.4 1.5 GO:0021812 neuronal-glial interaction involved in cerebral cortex radial glia guided migration(GO:0021812)
0.3 1.8 GO:0033030 negative regulation of neutrophil apoptotic process(GO:0033030)
0.3 2.4 GO:0006297 nucleotide-excision repair, DNA gap filling(GO:0006297)
0.3 5.8 GO:0046597 negative regulation of viral entry into host cell(GO:0046597)
0.2 6.3 GO:0051639 actin filament network formation(GO:0051639)
0.2 4.0 GO:0030322 stabilization of membrane potential(GO:0030322)
0.2 0.8 GO:0009051 pentose-phosphate shunt, oxidative branch(GO:0009051)
0.2 2.7 GO:0032875 regulation of DNA endoreduplication(GO:0032875)
0.2 0.6 GO:0060709 glycogen cell differentiation involved in embryonic placenta development(GO:0060709)
0.2 0.6 GO:0070103 regulation of interleukin-6-mediated signaling pathway(GO:0070103)
0.1 1.3 GO:2000234 positive regulation of ribosome biogenesis(GO:0090070) positive regulation of rRNA processing(GO:2000234)
0.1 0.4 GO:1904464 regulation of matrix metallopeptidase secretion(GO:1904464) matrix metallopeptidase secretion(GO:1990773)
0.1 0.5 GO:0072362 regulation of glycolytic process by negative regulation of transcription from RNA polymerase II promoter(GO:0072362)
0.1 1.7 GO:0018206 peptidyl-methionine modification(GO:0018206)
0.1 3.4 GO:0044381 glucose import in response to insulin stimulus(GO:0044381)
0.1 0.3 GO:1904266 regulation of Schwann cell chemotaxis(GO:1904266) positive regulation of Schwann cell chemotaxis(GO:1904268) Schwann cell chemotaxis(GO:1990751)
0.1 1.4 GO:0002227 innate immune response in mucosa(GO:0002227)
0.1 0.3 GO:0042539 hypotonic salinity response(GO:0042539) cellular hypotonic salinity response(GO:0071477)
0.1 0.9 GO:1902036 regulation of hematopoietic stem cell differentiation(GO:1902036)
0.1 0.2 GO:0015680 intracellular copper ion transport(GO:0015680)
0.1 2.9 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.1 0.6 GO:0033031 positive regulation of neutrophil apoptotic process(GO:0033031)
0.1 0.4 GO:1990481 mRNA pseudouridine synthesis(GO:1990481)
0.1 2.5 GO:0032288 myelin assembly(GO:0032288)
0.1 1.1 GO:0044154 histone H4-K12 acetylation(GO:0043983) histone H3-K14 acetylation(GO:0044154)
0.1 4.9 GO:0042982 amyloid precursor protein metabolic process(GO:0042982)
0.1 0.3 GO:0010025 wax biosynthetic process(GO:0010025) wax metabolic process(GO:0010166)
0.0 1.3 GO:0043968 histone H2A acetylation(GO:0043968)
0.0 0.1 GO:0019417 sulfur oxidation(GO:0019417)
0.0 0.7 GO:0019985 translesion synthesis(GO:0019985)
0.0 0.7 GO:0001778 plasma membrane repair(GO:0001778)
0.0 1.9 GO:0000305 response to oxygen radical(GO:0000305)
0.0 1.0 GO:0032516 positive regulation of phosphoprotein phosphatase activity(GO:0032516)
0.0 0.6 GO:0046085 adenosine metabolic process(GO:0046085)
0.0 0.2 GO:0010940 positive regulation of necrotic cell death(GO:0010940)
0.0 0.5 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.0 0.9 GO:0007080 mitotic metaphase plate congression(GO:0007080)
0.0 0.1 GO:0036015 response to interleukin-3(GO:0036015) cellular response to interleukin-3(GO:0036016)
0.0 1.6 GO:0006414 translational elongation(GO:0006414)
0.0 0.3 GO:0001682 tRNA 5'-leader removal(GO:0001682)
0.0 0.1 GO:2001074 negative regulation of metanephric glomerulus development(GO:0072299) negative regulation of metanephric glomerular mesangial cell proliferation(GO:0072302) regulation of metanephric ureteric bud development(GO:2001074) positive regulation of metanephric ureteric bud development(GO:2001076)
0.0 0.6 GO:0045948 positive regulation of translational initiation(GO:0045948)
0.0 0.1 GO:0000821 regulation of arginine metabolic process(GO:0000821)
0.0 0.1 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
0.0 0.1 GO:0048050 post-embryonic eye morphogenesis(GO:0048050) post-embryonic camera-type eye morphogenesis(GO:0048597)
0.0 0.4 GO:0042921 glucocorticoid receptor signaling pathway(GO:0042921)
0.0 0.3 GO:0034219 carbohydrate transmembrane transport(GO:0034219)
0.0 0.4 GO:0031295 T cell costimulation(GO:0031295)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.4 5.7 GO:0000942 condensed nuclear chromosome outer kinetochore(GO:0000942)
1.1 7.9 GO:0031095 platelet dense tubular network membrane(GO:0031095)
0.6 2.6 GO:0032127 dense core granule membrane(GO:0032127)
0.5 1.5 GO:0005607 laminin-2 complex(GO:0005607)
0.4 5.2 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.4 1.3 GO:0034455 t-UTP complex(GO:0034455)
0.4 6.4 GO:0042555 MCM complex(GO:0042555)
0.2 3.4 GO:0032593 insulin-responsive compartment(GO:0032593)
0.2 1.8 GO:0042629 mast cell granule(GO:0042629)
0.2 1.2 GO:0044615 nuclear pore nuclear basket(GO:0044615)
0.1 2.6 GO:0048188 Set1C/COMPASS complex(GO:0048188)
0.1 11.0 GO:0005871 kinesin complex(GO:0005871)
0.1 3.7 GO:0001891 phagocytic cup(GO:0001891)
0.1 0.7 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.1 1.3 GO:0000812 Swr1 complex(GO:0000812)
0.1 4.1 GO:0016592 mediator complex(GO:0016592)
0.1 1.1 GO:0008024 cyclin/CDK positive transcription elongation factor complex(GO:0008024)
0.1 2.5 GO:0043218 compact myelin(GO:0043218)
0.1 1.0 GO:0044327 dendritic spine head(GO:0044327)
0.0 0.3 GO:0000172 ribonuclease MRP complex(GO:0000172)
0.0 0.3 GO:0070652 HAUS complex(GO:0070652)
0.0 1.7 GO:0005790 smooth endoplasmic reticulum(GO:0005790)
0.0 0.7 GO:0033276 transcription factor TFTC complex(GO:0033276)
0.0 1.6 GO:0031902 late endosome membrane(GO:0031902)
0.0 0.3 GO:0060091 kinocilium(GO:0060091)
0.0 1.8 GO:0008180 COP9 signalosome(GO:0008180)
0.0 3.1 GO:0030667 secretory granule membrane(GO:0030667)
0.0 0.4 GO:0008540 proteasome regulatory particle, base subcomplex(GO:0008540) cytosolic proteasome complex(GO:0031597)
0.0 1.8 GO:0031901 early endosome membrane(GO:0031901)
0.0 0.8 GO:0030014 CCR4-NOT complex(GO:0030014)
0.0 0.1 GO:0071595 Nem1-Spo7 phosphatase complex(GO:0071595)
0.0 0.1 GO:0042721 mitochondrial inner membrane protein insertion complex(GO:0042721)
0.0 0.2 GO:0097524 sperm plasma membrane(GO:0097524)
0.0 2.6 GO:0000118 histone deacetylase complex(GO:0000118)
0.0 0.3 GO:1990635 proximal dendrite(GO:1990635)
0.0 1.9 GO:0000784 nuclear chromosome, telomeric region(GO:0000784)
0.0 1.4 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.0 0.6 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.0 0.1 GO:0097443 sorting endosome(GO:0097443)
0.0 3.1 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)
0.0 1.6 GO:0005643 nuclear pore(GO:0005643)
0.0 3.5 GO:0000794 condensed nuclear chromosome(GO:0000794)
0.0 0.3 GO:0005779 integral component of peroxisomal membrane(GO:0005779)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 5.7 GO:0010997 anaphase-promoting complex binding(GO:0010997)
0.7 3.4 GO:0055056 D-glucose transmembrane transporter activity(GO:0055056)
0.6 1.8 GO:0019959 interleukin-8 binding(GO:0019959)
0.6 1.7 GO:0016872 inositol-3-phosphate synthase activity(GO:0004512) intramolecular lyase activity(GO:0016872)
0.4 1.6 GO:0070139 ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139)
0.3 2.6 GO:0035312 5'-3' exodeoxyribonuclease activity(GO:0035312)
0.3 0.8 GO:0004616 phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
0.2 0.7 GO:0001129 RNA polymerase II transcription factor activity, TBP-class protein binding, involved in preinitiation complex assembly(GO:0001129) RNA polymerase II transcription factor activity, TBP-class protein binding(GO:0001132)
0.2 4.0 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.2 1.1 GO:0034211 GTP-dependent protein kinase activity(GO:0034211)
0.2 6.1 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.2 0.9 GO:1990188 euchromatin binding(GO:1990188)
0.2 1.5 GO:0043208 glycosphingolipid binding(GO:0043208)
0.2 1.8 GO:0035184 histone threonine kinase activity(GO:0035184)
0.1 6.4 GO:0004003 ATP-dependent DNA helicase activity(GO:0004003)
0.1 0.6 GO:0004711 ribosomal protein S6 kinase activity(GO:0004711)
0.1 1.6 GO:0046972 histone acetyltransferase activity (H4-K5 specific)(GO:0043995) histone acetyltransferase activity (H4-K8 specific)(GO:0043996) histone acetyltransferase activity (H4-K16 specific)(GO:0046972)
0.1 1.9 GO:0004791 thioredoxin-disulfide reductase activity(GO:0004791)
0.1 0.4 GO:0004450 isocitrate dehydrogenase (NADP+) activity(GO:0004450)
0.1 10.8 GO:0003777 microtubule motor activity(GO:0003777)
0.1 4.4 GO:0046966 thyroid hormone receptor binding(GO:0046966)
0.1 7.2 GO:0030507 spectrin binding(GO:0030507)
0.1 0.3 GO:0035827 rubidium ion transmembrane transporter activity(GO:0035827)
0.1 0.4 GO:0008240 tripeptidyl-peptidase activity(GO:0008240)
0.1 2.6 GO:0017166 vinculin binding(GO:0017166)
0.1 0.3 GO:0080019 fatty-acyl-CoA reductase (alcohol-forming) activity(GO:0080019)
0.1 0.3 GO:0038181 bile acid receptor activity(GO:0038181)
0.1 1.6 GO:0003746 translation elongation factor activity(GO:0003746)
0.1 0.2 GO:0004008 copper-exporting ATPase activity(GO:0004008) copper-transporting ATPase activity(GO:0043682)
0.1 0.3 GO:0102007 lactonohydrolase activity(GO:0046573) acyl-L-homoserine-lactone lactonohydrolase activity(GO:0102007)
0.0 0.6 GO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol bisphosphate kinase activity(GO:0052813)
0.0 0.5 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.0 0.6 GO:0030235 nitric-oxide synthase regulator activity(GO:0030235)
0.0 1.7 GO:0008235 metalloexopeptidase activity(GO:0008235)
0.0 2.1 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 1.3 GO:0030515 snoRNA binding(GO:0030515)
0.0 1.2 GO:0005487 nucleocytoplasmic transporter activity(GO:0005487)
0.0 2.3 GO:0031491 nucleosome binding(GO:0031491)
0.0 3.1 GO:0005080 protein kinase C binding(GO:0005080)
0.0 1.8 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.0 2.2 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.0 0.1 GO:0016434 rRNA (cytosine) methyltransferase activity(GO:0016434)
0.0 0.3 GO:0016427 tRNA (cytosine) methyltransferase activity(GO:0016427)
0.0 0.4 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.0 0.6 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.0 0.3 GO:0004526 ribonuclease P activity(GO:0004526)
0.0 0.1 GO:0030943 mitochondrion targeting sequence binding(GO:0030943)
0.0 2.6 GO:0004869 cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.0 0.1 GO:0038085 vascular endothelial growth factor binding(GO:0038085)
0.0 0.4 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.0 0.1 GO:0044729 hemi-methylated DNA-binding(GO:0044729)
0.0 0.2 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.0 0.4 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.0 3.4 GO:0051015 actin filament binding(GO:0051015)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 17.0 PID PLK1 PATHWAY PLK1 signaling events
0.1 6.2 PID ATR PATHWAY ATR signaling pathway
0.1 4.1 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.1 1.5 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.1 2.6 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.0 0.6 SA TRKA RECEPTOR The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.0 1.8 ST GRANULE CELL SURVIVAL PATHWAY Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.0 1.7 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.0 4.1 PID E2F PATHWAY E2F transcription factor network
0.0 1.8 PID A6B1 A6B4 INTEGRIN PATHWAY a6b1 and a6b4 Integrin signaling
0.0 1.1 SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES Genes related to the insulin receptor pathway
0.0 0.7 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.0 1.7 PID SMAD2 3NUCLEAR PATHWAY Regulation of nuclear SMAD2/3 signaling
0.0 0.1 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 6.4 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.3 11.0 REACTOME KINESINS Genes involved in Kinesins
0.3 5.7 REACTOME PHOSPHORYLATION OF THE APC C Genes involved in Phosphorylation of the APC/C
0.3 4.0 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.2 3.4 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.2 2.4 REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
0.1 2.6 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 0.6 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.0 0.6 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
0.0 1.2 REACTOME NEP NS2 INTERACTS WITH THE CELLULAR EXPORT MACHINERY Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery
0.0 1.8 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 0.8 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.0 1.0 REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.0 1.2 REACTOME MEIOTIC SYNAPSIS Genes involved in Meiotic Synapsis
0.0 0.7 REACTOME PIP3 ACTIVATES AKT SIGNALING Genes involved in PIP3 activates AKT signaling
0.0 0.4 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 0.6 REACTOME REGULATION OF SIGNALING BY CBL Genes involved in Regulation of signaling by CBL
0.0 1.9 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0 3.0 REACTOME TRANSLATION Genes involved in Translation
0.0 0.1 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions