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GSE58827: Dynamics of the Mouse Liver

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Results for Rela_Rel_Nfkb1

Z-value: 1.31

Motif logo

Transcription factors associated with Rela_Rel_Nfkb1

Gene Symbol Gene ID Gene Info
ENSMUSG00000024927.9 v-rel reticuloendotheliosis viral oncogene homolog A (avian)
ENSMUSG00000020275.10 reticuloendotheliosis oncogene
ENSMUSG00000028163.18 nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Nfkb1mm39_v1_chr3_-_135373560_1353735820.617.1e-05Click!
Relmm39_v1_chr11_-_23720953_237210280.501.9e-03Click!
Relamm39_v1_chr19_+_5687503_56875140.411.4e-02Click!

Activity profile of Rela_Rel_Nfkb1 motif

Sorted Z-values of Rela_Rel_Nfkb1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr5_-_92496730 4.51 ENSMUST00000038816.13
ENSMUST00000118006.3
chemokine (C-X-C motif) ligand 10
chr11_-_83421333 4.34 ENSMUST00000035938.3
chemokine (C-C motif) ligand 5
chr18_+_60936910 4.19 ENSMUST00000097563.9
ENSMUST00000050487.16
ENSMUST00000167610.2
CD74 antigen (invariant polypeptide of major histocompatibility complex, class II antigen-associated)
chr17_-_28736483 3.82 ENSMUST00000114792.8
ENSMUST00000177939.8
FK506 binding protein 5
chr17_+_43978377 3.53 ENSMUST00000233627.2
ENSMUST00000233437.2
cytochrome P450, family 39, subfamily a, polypeptide 1
chr17_+_43978280 3.43 ENSMUST00000170988.2
cytochrome P450, family 39, subfamily a, polypeptide 1
chr17_+_37504783 3.34 ENSMUST00000038844.7
ubiquitin D
chr7_+_25872836 3.19 ENSMUST00000082214.5
cytochrome P450, family 2, subfamily b, polypeptide 9
chr13_+_112600604 2.91 ENSMUST00000183663.8
ENSMUST00000184311.8
ENSMUST00000183886.8
interleukin 6 signal transducer
chr4_+_131649001 2.67 ENSMUST00000094666.4
transmembrane protein 200B
chr16_+_31241085 2.47 ENSMUST00000089759.9
3-hydroxybutyrate dehydrogenase, type 1
chr8_-_11329656 2.45 ENSMUST00000208095.2
collagen, type IV, alpha 1
chr5_+_91039092 2.42 ENSMUST00000031327.9
chemokine (C-X-C motif) ligand 1
chr9_-_14526246 2.37 ENSMUST00000013220.8
angiomotin-like 1
chr11_-_99383938 2.30 ENSMUST00000006969.8
keratin 23
chr9_-_70841881 2.22 ENSMUST00000214995.2
lipase, hepatic
chr19_-_7943365 2.19 ENSMUST00000182102.8
ENSMUST00000075619.5
solute carrier family 22, member 27
chr3_+_104696108 2.18 ENSMUST00000002303.12
ras homolog family member C
chr10_+_111342147 2.18 ENSMUST00000164773.2
pleckstrin homology like domain, family A, member 1
chr7_-_142223662 2.13 ENSMUST00000228850.2
predicted gene, 49394
chr10_-_95251327 2.04 ENSMUST00000172070.8
ENSMUST00000150432.8
suppressor of cytokine signaling 2
chr7_-_99276310 1.98 ENSMUST00000178124.3
trophoblast glycoprotein-like
chr17_-_35081456 1.97 ENSMUST00000025229.11
ENSMUST00000176203.9
ENSMUST00000128767.8
complement factor B
chr8_-_62355690 1.96 ENSMUST00000121785.9
ENSMUST00000034057.14
palladin, cytoskeletal associated protein
chr7_-_25488060 1.94 ENSMUST00000002677.11
ENSMUST00000085948.11
AXL receptor tyrosine kinase
chr18_-_35855383 1.90 ENSMUST00000133064.8
endothelial cell surface expressed chemotaxis and apoptosis regulator
chr10_-_95251145 1.89 ENSMUST00000119917.2
suppressor of cytokine signaling 2
chr10_-_127843377 1.86 ENSMUST00000219447.2
ENSMUST00000219780.2
ENSMUST00000219707.2
ENSMUST00000219953.2
ENSMUST00000219183.2
hydroxysteroid (17-beta) dehydrogenase 6
chr11_-_48884999 1.84 ENSMUST00000146439.8
T cell specific GTPase 1
chr7_-_19363280 1.77 ENSMUST00000094762.10
ENSMUST00000049912.15
ENSMUST00000098754.5
avian reticuloendotheliosis viral (v-rel) oncogene related B
chr8_+_72128920 1.73 ENSMUST00000110013.10
ENSMUST00000051995.14
Janus kinase 3
chr9_-_70842090 1.71 ENSMUST00000034731.10
lipase, hepatic
chr5_-_105441554 1.66 ENSMUST00000050011.10
ENSMUST00000196520.2
predicted gene 43302
guanylate binding protein 6
chr12_+_111383864 1.63 ENSMUST00000220537.2
ENSMUST00000223050.2
ENSMUST00000072646.8
ENSMUST00000223431.2
ENSMUST00000221144.2
ENSMUST00000222437.2
exocyst complex component 3-like 4
chr17_-_45997823 1.62 ENSMUST00000156254.8
transmembrane protein 63b
chr9_-_44646487 1.58 ENSMUST00000034611.15
pleckstrin homology like domain, family B, member 1
chr14_+_33662976 1.57 ENSMUST00000100720.2
growth differentiation factor 2
chr12_-_35584968 1.55 ENSMUST00000116436.9
aryl-hydrocarbon receptor
chr4_+_137408975 1.54 ENSMUST00000047243.12
Rap1 GTPase-activating protein
chr17_-_56312555 1.52 ENSMUST00000043785.8
signal transducing adaptor family member 2
chr7_+_75498058 1.51 ENSMUST00000171155.4
ENSMUST00000092073.11
ENSMUST00000206019.2
ENSMUST00000205612.2
ENSMUST00000205887.2
kelch-like 25
chrX_-_73290140 1.51 ENSMUST00000101454.9
ENSMUST00000033699.13
filamin, alpha
chr19_+_3372296 1.47 ENSMUST00000237938.2
carnitine palmitoyltransferase 1a, liver
chr7_-_44465043 1.47 ENSMUST00000107893.9
activating transcription factor 5
chr1_+_172327569 1.46 ENSMUST00000111230.8
transgelin 2
chr13_+_43938251 1.44 ENSMUST00000015540.4
CD83 antigen
chrX_-_73289970 1.42 ENSMUST00000130007.8
filamin, alpha
chr11_+_101066867 1.39 ENSMUST00000103109.4
contactin associated protein-like 1
chr17_+_35598583 1.39 ENSMUST00000081435.5
histocompatibility 2, Q region locus 4
chr12_+_104180795 1.32 ENSMUST00000121337.8
ENSMUST00000167049.8
ENSMUST00000101080.2
serine (or cysteine) peptidase inhibitor, clade A, member 3F
chr1_+_172327812 1.30 ENSMUST00000192460.2
transgelin 2
chr3_+_96508400 1.29 ENSMUST00000062058.5
Lix1-like
chr14_-_45767421 1.28 ENSMUST00000150660.3
fermitin family member 2
chr4_-_101122433 1.27 ENSMUST00000149297.2
ENSMUST00000102781.10
Janus kinase 1
chr9_+_32607301 1.25 ENSMUST00000034534.13
ENSMUST00000050797.14
ENSMUST00000184887.2
E26 avian leukemia oncogene 1, 5' domain
chr17_-_34506744 1.22 ENSMUST00000174751.2
ENSMUST00000040655.14
histocompatibility 2, class II antigen A, alpha
chr10_-_127587576 1.22 ENSMUST00000079692.6
G protein-coupled receptor 182
chr18_+_11972277 1.22 ENSMUST00000171109.9
ENSMUST00000046948.10
CDK5 and Abl enzyme substrate 1
chr16_+_44913974 1.21 ENSMUST00000099498.10
coiled-coil domain containing 80
chr2_-_32278245 1.21 ENSMUST00000192241.2
lipocalin 2
chr1_+_87983099 1.19 ENSMUST00000138182.8
ENSMUST00000113142.10
UDP glycosyltransferase 1 family, polypeptide A10
chr5_+_8010445 1.18 ENSMUST00000115421.3
STEAP family member 4
chr17_+_35413415 1.16 ENSMUST00000025262.6
ENSMUST00000173600.2
lymphotoxin B
chr2_-_32277773 1.16 ENSMUST00000050785.14
lipocalin 2
chr1_+_134121170 1.15 ENSMUST00000038445.13
ENSMUST00000191577.2
myosin binding protein H
chr3_-_83749036 1.14 ENSMUST00000029623.11
toll-like receptor 2
chr1_+_171041539 1.14 ENSMUST00000005820.11
ENSMUST00000075469.12
ENSMUST00000155126.8
nuclear receptor subfamily 1, group I, member 3
chr17_+_56259617 1.12 ENSMUST00000003274.8
Epstein-Barr virus induced gene 3
chr14_-_70585874 1.12 ENSMUST00000152067.8
solute carrier family 39 (zinc transporter), member 14
chr12_+_29988035 1.11 ENSMUST00000122328.8
ENSMUST00000118321.3
peroxidasin
chr12_-_80307110 1.11 ENSMUST00000021554.16
actinin, alpha 1
chr18_-_20192535 1.10 ENSMUST00000075214.9
ENSMUST00000039247.11
desmocollin 2
chr4_-_107164315 1.09 ENSMUST00000126291.2
ENSMUST00000106748.2
ENSMUST00000129138.2
deiodinase, iodothyronine, type I
chr1_+_171041583 1.08 ENSMUST00000111328.8
nuclear receptor subfamily 1, group I, member 3
chr6_+_48818410 1.07 ENSMUST00000101426.11
ENSMUST00000168406.4
transmembrane protein 176A
chr11_+_70431063 1.06 ENSMUST00000018429.12
ENSMUST00000108557.10
ENSMUST00000108556.2
phospholipase D2
chr12_+_84085709 1.04 ENSMUST00000221229.2
predicted gene, 49366
chr6_-_41012435 1.01 ENSMUST00000031931.6
RIKEN cDNA 2210010C04 gene
chr16_-_18052937 1.01 ENSMUST00000076957.7
zinc finger, DHHC domain containing 8
chr17_-_24424456 1.00 ENSMUST00000201583.2
ENSMUST00000202925.4
ENSMUST00000167791.9
ENSMUST00000201960.4
ENSMUST00000040474.11
ENSMUST00000201089.4
ENSMUST00000201301.4
ENSMUST00000201805.4
ENSMUST00000168410.9
ENSMUST00000097376.10
TBC1 domain family, member 24
chr10_-_86843878 1.00 ENSMUST00000035288.17
stabilin 2
chr1_-_172418058 1.00 ENSMUST00000065679.8
SLAM family member 8
chr1_+_87983189 0.96 ENSMUST00000173325.2
UDP glycosyltransferase 1 family, polypeptide A10
chr11_-_75329726 0.95 ENSMUST00000108437.8
serine (or cysteine) peptidase inhibitor, clade F, member 2
chr9_+_90045109 0.94 ENSMUST00000113059.8
ENSMUST00000167122.8
a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 7
chr11_-_54846873 0.94 ENSMUST00000155316.2
ENSMUST00000108889.10
ENSMUST00000126703.8
TNFAIP3 interacting protein 1
chr4_+_131648509 0.93 ENSMUST00000238733.2
transmembrane protein 200B
chr16_-_17711950 0.93 ENSMUST00000155943.9
DiGeorge syndrome critical region gene 2
chr8_+_89309408 0.93 ENSMUST00000211113.2
naked cuticle 1
chr16_+_32734464 0.92 ENSMUST00000023491.13
ENSMUST00000170899.8
ENSMUST00000170201.8
ENSMUST00000165616.8
ENSMUST00000135193.9
leucine-rich repeats and calponin homology (CH) domain containing 3
chr17_+_25097199 0.91 ENSMUST00000050714.8
insulin-like growth factor binding protein, acid labile subunit
chr4_+_136013372 0.91 ENSMUST00000069195.5
ENSMUST00000130658.2
zinc finger protein 46
chr1_-_135186176 0.91 ENSMUST00000185752.2
ENSMUST00000003135.14
E74-like factor 3
chr14_-_104081119 0.90 ENSMUST00000227824.2
ENSMUST00000172237.2
endothelin receptor type B
chr19_+_34268053 0.90 ENSMUST00000025691.13
Fas (TNF receptor superfamily member 6)
chr18_+_36693646 0.89 ENSMUST00000155329.9
ankyrin repeat and KH domain containing 1
chr2_-_118377500 0.88 ENSMUST00000125860.3
BCL2 modifying factor
chr9_+_107784065 0.87 ENSMUST00000035203.9
macrophage stimulating 1 receptor (c-met-related tyrosine kinase)
chr10_+_128139227 0.86 ENSMUST00000218315.2
ENSMUST00000219721.2
PAN2 poly(A) specific ribonuclease subunit
chr2_+_91090167 0.86 ENSMUST00000138470.2
protein kinase C and casein kinase substrate in neurons 3
chr11_-_106050724 0.86 ENSMUST00000064545.11
LIM domain containing 2
chr5_-_105287405 0.85 ENSMUST00000100961.5
ENSMUST00000031235.13
ENSMUST00000197799.2
ENSMUST00000199629.2
ENSMUST00000196677.5
ENSMUST00000100962.8
guanylate-binding protein 9
guanylate-binding protein 8
guanylate binding protein 4
chr11_-_69771797 0.83 ENSMUST00000238978.2
potassium channel tetramerisation domain containing 11
chr14_-_45767575 0.81 ENSMUST00000045905.15
fermitin family member 2
chr2_-_6217844 0.80 ENSMUST00000042658.5
enoyl Coenzyme A hydratase domain containing 3
chr2_-_5068807 0.80 ENSMUST00000114996.8
optineurin
chr12_+_86725459 0.78 ENSMUST00000021681.4
vasohibin 1
chr2_-_32321116 0.77 ENSMUST00000127961.3
ENSMUST00000136361.8
ENSMUST00000052119.14
solute carrier family 25 (mitochondrial carrier, phosphate carrier), member 25
chr3_-_135397298 0.76 ENSMUST00000029812.14
nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105
chr3_+_142326363 0.75 ENSMUST00000165774.8
guanylate binding protein 2
chr11_-_30148230 0.75 ENSMUST00000102838.10
spectrin beta, non-erythrocytic 1
chr19_+_34268071 0.75 ENSMUST00000112472.4
ENSMUST00000235232.2
Fas (TNF receptor superfamily member 6)
chr14_-_70588803 0.75 ENSMUST00000143153.2
ENSMUST00000127000.2
ENSMUST00000068044.14
ENSMUST00000022688.10
solute carrier family 39 (zinc transporter), member 14
chr2_-_160155536 0.74 ENSMUST00000109475.3
predicted gene 826
chr2_+_13578738 0.74 ENSMUST00000141365.3
ENSMUST00000028062.8
vimentin
chr6_-_48818430 0.73 ENSMUST00000205147.3
transmembrane protein 176B
chr11_-_54853729 0.72 ENSMUST00000108885.8
ENSMUST00000102730.9
ENSMUST00000018482.13
ENSMUST00000108886.8
ENSMUST00000102731.8
TNFAIP3 interacting protein 1
chr11_-_51647204 0.71 ENSMUST00000109092.8
ENSMUST00000064297.5
Sec24 related gene family, member A (S. cerevisiae)
chr14_+_14475188 0.71 ENSMUST00000026315.8
deoxyribonuclease 1-like 3
chr7_+_95860863 0.71 ENSMUST00000107165.8
teneurin transmembrane protein 4
chr6_-_48818006 0.71 ENSMUST00000203229.3
transmembrane protein 176B
chr11_+_100750316 0.71 ENSMUST00000107356.8
signal transducer and activator of transcription 5A
chr15_+_6599001 0.70 ENSMUST00000227175.2
FYN binding protein
chr5_+_72805153 0.70 ENSMUST00000197837.3
NIPA-like domain containing 1
chr5_-_134707042 0.70 ENSMUST00000111233.8
LIM-domain containing, protein kinase
chr1_-_60606237 0.70 ENSMUST00000142258.3
Ras association (RalGDS/AF-6) and pleckstrin homology domains 1
chr3_-_121056944 0.70 ENSMUST00000128909.8
ENSMUST00000029777.14
TLC domain containing 4
chr12_-_101785307 0.70 ENSMUST00000021603.9
fibulin 5
chr16_+_23109213 0.70 ENSMUST00000115335.2
beta galactoside alpha 2,6 sialyltransferase 1
chr2_-_5068743 0.69 ENSMUST00000027986.5
optineurin
chr11_+_69471185 0.69 ENSMUST00000171247.8
ENSMUST00000108658.10
ENSMUST00000005371.12
transformation related protein 53
chr3_+_37694094 0.69 ENSMUST00000108109.8
ENSMUST00000038569.8
ENSMUST00000108107.2
sprouty RTK signaling antagonist 1
chr6_-_48818302 0.69 ENSMUST00000203355.3
ENSMUST00000166247.8
transmembrane protein 176B
chr8_-_25591737 0.69 ENSMUST00000098866.11
pleckstrin homology domain-containing, family A (phosphoinositide binding specific) member 2
chr10_+_128626772 0.68 ENSMUST00000219404.2
ENSMUST00000026411.8
matrix metallopeptidase 19
chr7_-_109215960 0.68 ENSMUST00000077909.9
DENN domain containing 2B
chr16_-_30086317 0.67 ENSMUST00000064856.9
carboxypeptidase N, polypeptide 2
chr11_+_48977852 0.67 ENSMUST00000046704.7
ENSMUST00000203810.3
ENSMUST00000203149.3
interferon gamma inducible protein 47
olfactory receptor 56
chr1_-_36312482 0.66 ENSMUST00000056946.8
neuralized E3 ubiquitin protein ligase 3
chr13_-_36918424 0.66 ENSMUST00000037623.15
neuritin 1
chr7_+_28466160 0.66 ENSMUST00000122915.8
ENSMUST00000072965.5
ENSMUST00000170068.9
sirtuin 2
chr3_-_115923098 0.66 ENSMUST00000196449.5
vascular cell adhesion molecule 1
chr5_-_38649291 0.65 ENSMUST00000129099.8
solute carrier family 2 (facilitated glucose transporter), member 9
chr2_-_166902307 0.65 ENSMUST00000155281.8
zinc finger, NFX1-type containing 1
chr13_+_93810911 0.65 ENSMUST00000048001.8
dimethylglycine dehydrogenase precursor
chr10_+_128139191 0.65 ENSMUST00000005825.8
PAN2 poly(A) specific ribonuclease subunit
chr12_-_80306865 0.65 ENSMUST00000167327.2
actinin, alpha 1
chr4_+_130643260 0.65 ENSMUST00000030316.7
lysosomal-associated protein transmembrane 5
chr8_-_25592001 0.64 ENSMUST00000128715.8
pleckstrin homology domain-containing, family A (phosphoinositide binding specific) member 2
chr11_+_104441489 0.64 ENSMUST00000018800.9
myosin, light polypeptide 4
chr11_-_83469446 0.64 ENSMUST00000019266.6
chemokine (C-C motif) ligand 9
chr2_+_84880776 0.64 ENSMUST00000111605.9
tankyrase 1 binding protein 1
chr6_-_48817914 0.63 ENSMUST00000164733.4
transmembrane protein 176B
chr11_+_48977888 0.63 ENSMUST00000214804.2
interferon gamma inducible protein 47
chr3_-_107667499 0.63 ENSMUST00000153114.2
ENSMUST00000118593.8
ENSMUST00000120243.8
colony stimulating factor 1 (macrophage)
chr6_+_15720653 0.63 ENSMUST00000101663.10
ENSMUST00000190255.7
ENSMUST00000189359.7
ENSMUST00000125326.8
MyoD family inhibitor domain containing
chr15_-_89263128 0.63 ENSMUST00000227834.2
outer dense fiber of sperm tails 3B
chr3_+_89987749 0.63 ENSMUST00000127955.2
tropomyosin 3, gamma
chr10_-_81266800 0.62 ENSMUST00000117966.2
nuclear factor I/C
chr8_-_25592385 0.61 ENSMUST00000064883.14
pleckstrin homology domain-containing, family A (phosphoinositide binding specific) member 2
chrX_+_135039745 0.61 ENSMUST00000116527.2
brain expressed X-linked 4
chr11_+_97690585 0.61 ENSMUST00000129558.8
LIM and SH3 protein 1
chr3_+_142202642 0.61 ENSMUST00000090127.7
guanylate binding protein 5
chr1_-_173707677 0.60 ENSMUST00000190651.4
ENSMUST00000188804.7
myeloid nuclear differentiation antigen like
chr9_-_14526768 0.59 ENSMUST00000162901.8
angiomotin-like 1
chr19_-_10582773 0.59 ENSMUST00000237788.2
triokinase, FMN cyclase
chr9_+_69361348 0.59 ENSMUST00000134907.8
annexin A2
chr14_-_54655079 0.58 ENSMUST00000226753.2
ENSMUST00000197440.5
solute carrier family 7 (cationic amino acid transporter, y+ system), member 7
chr19_-_10582672 0.58 ENSMUST00000236478.2
ENSMUST00000236950.2
triokinase, FMN cyclase
chr17_-_45996899 0.57 ENSMUST00000145873.8
transmembrane protein 63b
chr17_-_45997046 0.57 ENSMUST00000143907.3
ENSMUST00000127065.8
transmembrane protein 63b
chr1_-_170886924 0.57 ENSMUST00000164044.8
ENSMUST00000169017.8
Fc receptor, IgG, low affinity III
chr3_-_67371161 0.57 ENSMUST00000058981.3
latexin
chr2_+_29855572 0.57 ENSMUST00000113719.9
ENSMUST00000113717.8
ENSMUST00000113741.8
ENSMUST00000100225.9
ENSMUST00000095083.11
ENSMUST00000046257.14
spectrin alpha, non-erythrocytic 1
chr11_+_97689819 0.57 ENSMUST00000143571.2
LIM and SH3 protein 1
chr15_+_81629258 0.57 ENSMUST00000109554.3
ENSMUST00000230946.2
zinc finger CCCH type containing 7B
chr6_-_48818044 0.57 ENSMUST00000101429.11
ENSMUST00000204073.3
transmembrane protein 176B
chr17_+_34406523 0.56 ENSMUST00000170086.8
transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
chr4_+_102446883 0.56 ENSMUST00000097949.11
ENSMUST00000106901.2
phosphodiesterase 4B, cAMP specific
chr7_-_44180700 0.56 ENSMUST00000205506.2
Spi-B transcription factor (Spi-1/PU.1 related)
chr19_-_58442866 0.56 ENSMUST00000169850.8
glial cell line derived neurotrophic factor family receptor alpha 1
chr2_+_13579092 0.56 ENSMUST00000193675.2
vimentin
chr18_-_4352944 0.54 ENSMUST00000025078.10
mitogen-activated protein kinase kinase kinase 8
chr14_-_36690636 0.54 ENSMUST00000067700.13
coiled-coil serine rich 2
chr13_-_64518112 0.54 ENSMUST00000021933.8
ENSMUST00000222462.2
cathepsin L
chr5_+_65127412 0.53 ENSMUST00000031080.15
family with sequence similarity 114, member A1
chr13_+_31740117 0.53 ENSMUST00000042118.11
forkhead box Q1
chr18_+_84869456 0.53 ENSMUST00000160180.9
cytochrome b5 type A (microsomal)
chr6_+_68233361 0.53 ENSMUST00000103320.3
immunoglobulin kappa variable 14-111
chr9_-_7873171 0.52 ENSMUST00000159323.2
ENSMUST00000115673.3
baculoviral IAP repeat-containing 3
chr11_+_100751272 0.52 ENSMUST00000107357.4
signal transducer and activator of transcription 5A
chr6_-_137146708 0.52 ENSMUST00000117919.8
RAS-like, estrogen-regulated, growth-inhibitor
chr9_+_69360902 0.52 ENSMUST00000034756.15
ENSMUST00000123470.8
annexin A2
chr2_-_164285097 0.52 ENSMUST00000017153.4
syndecan 4
chr6_-_125208738 0.52 ENSMUST00000043422.8
TAP binding protein-like
chr4_-_45012093 0.52 ENSMUST00000131991.2
zinc finger and BTB domain containing 5
chr12_+_111132908 0.51 ENSMUST00000139162.8
ENSMUST00000060274.7
TNF receptor-associated factor 3
chr17_-_45997132 0.51 ENSMUST00000113523.9
transmembrane protein 63b
chr18_+_4994600 0.51 ENSMUST00000140448.8
supervillin
chr17_+_34406762 0.51 ENSMUST00000041633.15
transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)

Network of associatons between targets according to the STRING database.

First level regulatory network of Rela_Rel_Nfkb1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
2.3 7.0 GO:0030573 bile acid catabolic process(GO:0030573)
1.1 3.4 GO:0003365 establishment of cell polarity involved in ameboidal cell migration(GO:0003365)
1.1 4.5 GO:1901740 negative regulation of myoblast fusion(GO:1901740)
1.1 4.3 GO:2000503 positive regulation of natural killer cell chemotaxis(GO:2000503)
1.0 2.9 GO:1905000 regulation of membrane repolarization during atrial cardiac muscle cell action potential(GO:1905000)
0.9 2.8 GO:0070104 negative regulation of interleukin-6-mediated signaling pathway(GO:0070104)
0.8 4.2 GO:0002901 mature B cell apoptotic process(GO:0002901) regulation of mature B cell apoptotic process(GO:0002905) negative regulation of mature B cell apoptotic process(GO:0002906)
0.8 2.4 GO:0070947 neutrophil mediated killing of fungus(GO:0070947)
0.8 2.4 GO:0015891 iron chelate transport(GO:0015688) siderophore transport(GO:0015891)
0.8 3.9 GO:0034371 chylomicron remodeling(GO:0034371)
0.7 3.7 GO:0097048 dendritic cell apoptotic process(GO:0097048) regulation of dendritic cell apoptotic process(GO:2000668)
0.5 1.6 GO:0031104 dendrite regeneration(GO:0031104)
0.5 1.4 GO:1904093 regulation of autophagic cell death(GO:1904092) negative regulation of autophagic cell death(GO:1904093)
0.4 1.5 GO:1904425 negative regulation of GTP binding(GO:1904425)
0.4 1.1 GO:0032741 positive regulation of interleukin-18 production(GO:0032741) detection of triacyl bacterial lipopeptide(GO:0042495) response to immune response of other organism involved in symbiotic interaction(GO:0052564) response to host immune response(GO:0052572)
0.4 1.1 GO:1904024 negative regulation of NAD metabolic process(GO:1902689) negative regulation of glucose catabolic process to lactate via pyruvate(GO:1904024)
0.4 4.9 GO:2001199 negative regulation of dendritic cell differentiation(GO:2001199)
0.4 1.1 GO:0046967 cytosol to ER transport(GO:0046967)
0.3 1.0 GO:1902623 negative regulation of neutrophil migration(GO:1902623)
0.3 0.6 GO:1902226 regulation of macrophage colony-stimulating factor signaling pathway(GO:1902226) regulation of response to macrophage colony-stimulating factor(GO:1903969) regulation of cellular response to macrophage colony-stimulating factor stimulus(GO:1903972)
0.3 1.7 GO:2000525 regulation of T cell costimulation(GO:2000523) positive regulation of T cell costimulation(GO:2000525)
0.3 1.1 GO:0060376 positive regulation of mast cell differentiation(GO:0060376)
0.3 2.4 GO:0061304 retinal blood vessel morphogenesis(GO:0061304)
0.3 0.8 GO:1990051 negative regulation of phospholipase C activity(GO:1900275) activation of protein kinase C activity(GO:1990051)
0.3 1.5 GO:0040010 positive regulation of growth rate(GO:0040010)
0.3 3.3 GO:0070842 aggresome assembly(GO:0070842)
0.3 1.3 GO:0036015 response to interleukin-3(GO:0036015) cellular response to interleukin-3(GO:0036016)
0.3 0.8 GO:1904632 negative regulation of interleukin-12 biosynthetic process(GO:0045083) response to diterpene(GO:1904629) cellular response to diterpene(GO:1904630) response to glucoside(GO:1904631) cellular response to glucoside(GO:1904632)
0.2 1.5 GO:0061734 parkin-mediated mitophagy in response to mitochondrial depolarization(GO:0061734)
0.2 1.0 GO:2000795 negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
0.2 0.7 GO:1900195 positive regulation of oocyte maturation(GO:1900195) positive regulation of proteasomal ubiquitin-dependent protein catabolic process involved in cellular response to hypoxia(GO:2000777)
0.2 0.6 GO:0014805 smooth muscle adaptation(GO:0014805)
0.2 0.4 GO:0061300 cerebellum vasculature development(GO:0061300)
0.2 0.8 GO:1901491 negative regulation of lymphangiogenesis(GO:1901491)
0.2 0.6 GO:0001788 antibody-dependent cellular cytotoxicity(GO:0001788)
0.2 1.1 GO:0032804 negative regulation of low-density lipoprotein particle receptor catabolic process(GO:0032804)
0.2 2.1 GO:0052697 flavonoid glucuronidation(GO:0052696) xenobiotic glucuronidation(GO:0052697)
0.2 0.7 GO:0060912 cardiac cell fate specification(GO:0060912)
0.2 0.4 GO:0046226 coumarin catabolic process(GO:0046226)
0.2 0.5 GO:0002589 regulation of antigen processing and presentation of peptide antigen via MHC class I(GO:0002589) negative regulation of antigen processing and presentation of peptide antigen via MHC class I(GO:0002590)
0.2 0.7 GO:0051387 negative regulation of neurotrophin TRK receptor signaling pathway(GO:0051387)
0.2 0.7 GO:0038016 insulin receptor internalization(GO:0038016)
0.2 1.2 GO:0006001 fructose catabolic process(GO:0006001) fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate(GO:0061624) glycolytic process through fructose-1-phosphate(GO:0061625)
0.2 1.3 GO:1900147 Schwann cell migration(GO:0036135) regulation of Schwann cell migration(GO:1900147)
0.2 0.8 GO:0002266 follicular dendritic cell activation(GO:0002266) follicular dendritic cell differentiation(GO:0002268)
0.2 0.8 GO:0009597 detection of virus(GO:0009597)
0.2 1.4 GO:0045084 positive regulation of interleukin-12 biosynthetic process(GO:0045084)
0.1 4.2 GO:0060396 growth hormone receptor signaling pathway(GO:0060396) cellular response to growth hormone stimulus(GO:0071378)
0.1 0.9 GO:0014826 vein smooth muscle contraction(GO:0014826)
0.1 2.2 GO:0015747 urate transport(GO:0015747)
0.1 0.4 GO:0046168 glycerol-3-phosphate catabolic process(GO:0046168)
0.1 0.4 GO:0042668 trochlear nerve development(GO:0021558) auditory receptor cell fate determination(GO:0042668) negative regulation of forebrain neuron differentiation(GO:2000978)
0.1 1.4 GO:0032713 negative regulation of interleukin-4 production(GO:0032713)
0.1 0.3 GO:0042091 interleukin-10 biosynthetic process(GO:0042091) regulation of interleukin-10 biosynthetic process(GO:0045074)
0.1 0.7 GO:1990743 protein sialylation(GO:1990743)
0.1 1.2 GO:1904996 positive regulation of leukocyte adhesion to vascular endothelial cell(GO:1904996)
0.1 3.4 GO:0044406 adhesion of symbiont to host(GO:0044406)
0.1 0.9 GO:0038031 non-canonical Wnt signaling pathway via JNK cascade(GO:0038031)
0.1 0.7 GO:0045347 negative regulation of MHC class II biosynthetic process(GO:0045347)
0.1 0.4 GO:0061144 alveolar secondary septum development(GO:0061144)
0.1 1.4 GO:0002175 protein localization to paranode region of axon(GO:0002175)
0.1 0.5 GO:0002479 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent(GO:0002479) peptide stabilization(GO:0050822) peptide antigen stabilization(GO:0050823)
0.1 1.1 GO:0086073 bundle of His cell-Purkinje myocyte adhesion involved in cell communication(GO:0086073)
0.1 3.8 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.1 2.1 GO:0051601 exocyst localization(GO:0051601)
0.1 0.2 GO:0042374 phylloquinone metabolic process(GO:0042374) phylloquinone catabolic process(GO:0042376) quinone catabolic process(GO:1901662)
0.1 1.0 GO:0002034 regulation of blood vessel size by renin-angiotensin(GO:0002034) renal control of peripheral vascular resistance involved in regulation of systemic arterial blood pressure(GO:0003072)
0.1 1.2 GO:0098706 ferric iron import into cell(GO:0097461) ferric iron import across plasma membrane(GO:0098706)
0.1 2.0 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.1 0.4 GO:0030091 protein repair(GO:0030091)
0.1 1.5 GO:0021891 olfactory bulb interneuron development(GO:0021891)
0.1 0.3 GO:0060010 Sertoli cell fate commitment(GO:0060010)
0.1 0.4 GO:2000984 regulation of ATP citrate synthase activity(GO:2000983) negative regulation of ATP citrate synthase activity(GO:2000984)
0.1 1.5 GO:1904261 regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904259) positive regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904261) basement membrane assembly involved in embryonic body morphogenesis(GO:2001197)
0.1 3.2 GO:0019373 epoxygenase P450 pathway(GO:0019373)
0.1 2.2 GO:0043011 myeloid dendritic cell differentiation(GO:0043011)
0.1 1.5 GO:0032000 positive regulation of fatty acid beta-oxidation(GO:0032000)
0.1 0.4 GO:0070295 renal water absorption(GO:0070295)
0.1 0.5 GO:1903553 positive regulation of extracellular exosome assembly(GO:1903553)
0.1 0.3 GO:1903281 positive regulation of calcium:sodium antiporter activity(GO:1903281)
0.1 0.8 GO:0007182 common-partner SMAD protein phosphorylation(GO:0007182)
0.1 0.8 GO:0007406 negative regulation of neuroblast proliferation(GO:0007406)
0.1 1.7 GO:0071803 positive regulation of podosome assembly(GO:0071803)
0.1 0.2 GO:0003245 cardiac muscle tissue growth involved in heart morphogenesis(GO:0003245)
0.1 1.5 GO:0000291 nuclear-transcribed mRNA catabolic process, exonucleolytic(GO:0000291)
0.1 0.9 GO:2000189 positive regulation of cholesterol homeostasis(GO:2000189)
0.1 2.0 GO:2000353 positive regulation of endothelial cell apoptotic process(GO:2000353)
0.1 1.8 GO:0051764 actin crosslink formation(GO:0051764)
0.1 2.0 GO:0035455 response to interferon-alpha(GO:0035455)
0.1 0.4 GO:0016557 peroxisome membrane biogenesis(GO:0016557)
0.1 0.7 GO:0060710 chorio-allantoic fusion(GO:0060710)
0.1 0.7 GO:0019695 choline metabolic process(GO:0019695)
0.1 1.1 GO:0071688 striated muscle myosin thick filament assembly(GO:0071688)
0.1 0.6 GO:0032621 interleukin-18 production(GO:0032621)
0.1 0.2 GO:0034769 basement membrane disassembly(GO:0034769)
0.1 1.5 GO:0002755 MyD88-dependent toll-like receptor signaling pathway(GO:0002755)
0.1 0.3 GO:0006772 thiamine metabolic process(GO:0006772) thiamine-containing compound metabolic process(GO:0042723)
0.1 0.4 GO:0038161 prolactin signaling pathway(GO:0038161)
0.1 0.2 GO:0034148 regulation of granuloma formation(GO:0002631) negative regulation of granuloma formation(GO:0002632) regulation of toll-like receptor 5 signaling pathway(GO:0034147) negative regulation of toll-like receptor 5 signaling pathway(GO:0034148) negative regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070429)
0.1 0.6 GO:0008063 Toll signaling pathway(GO:0008063)
0.1 0.4 GO:0060523 prostate epithelial cord elongation(GO:0060523)
0.1 1.7 GO:0071577 zinc II ion transmembrane transport(GO:0071577)
0.1 0.3 GO:0072365 regulation of cellular ketone metabolic process by negative regulation of transcription from RNA polymerase II promoter(GO:0072365)
0.1 1.2 GO:0019886 antigen processing and presentation of exogenous peptide antigen via MHC class II(GO:0019886)
0.1 0.4 GO:1902998 regulation of neuronal signal transduction(GO:1902847) positive regulation of neurofibrillary tangle assembly(GO:1902998)
0.1 0.2 GO:0015744 succinate transport(GO:0015744)
0.1 0.3 GO:0072733 response to staurosporine(GO:0072733) cellular response to staurosporine(GO:0072734)
0.1 0.7 GO:0048251 elastic fiber assembly(GO:0048251)
0.1 0.3 GO:0044727 DNA demethylation of male pronucleus(GO:0044727)
0.1 0.9 GO:0030948 negative regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030948)
0.1 0.3 GO:0090038 negative regulation of protein kinase C signaling(GO:0090038)
0.1 0.2 GO:1904211 membrane protein proteolysis involved in retrograde protein transport, ER to cytosol(GO:1904211)
0.1 0.5 GO:0071802 negative regulation of podosome assembly(GO:0071802)
0.1 0.4 GO:0021564 vagus nerve development(GO:0021564)
0.1 1.0 GO:0010623 programmed cell death involved in cell development(GO:0010623)
0.1 1.7 GO:0032757 positive regulation of interleukin-8 production(GO:0032757)
0.1 1.9 GO:0033622 integrin activation(GO:0033622)
0.1 0.7 GO:0036462 TRAIL-activated apoptotic signaling pathway(GO:0036462)
0.1 0.2 GO:1904882 telomerase catalytic core complex assembly(GO:1904868) regulation of telomerase catalytic core complex assembly(GO:1904882) positive regulation of telomerase catalytic core complex assembly(GO:1904884)
0.1 0.5 GO:0015961 diadenosine polyphosphate catabolic process(GO:0015961)
0.1 0.9 GO:0060056 mammary gland involution(GO:0060056)
0.1 0.7 GO:0019321 pentose metabolic process(GO:0019321)
0.1 0.3 GO:0036343 psychomotor behavior(GO:0036343)
0.1 0.4 GO:0045086 positive regulation of interleukin-2 biosynthetic process(GO:0045086)
0.0 0.2 GO:0045657 positive regulation of monocyte differentiation(GO:0045657)
0.0 0.5 GO:0010838 positive regulation of keratinocyte proliferation(GO:0010838)
0.0 0.9 GO:0015693 magnesium ion transport(GO:0015693)
0.0 0.4 GO:0042663 regulation of endodermal cell fate specification(GO:0042663)
0.0 0.5 GO:0042637 catagen(GO:0042637)
0.0 0.8 GO:1902083 negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.0 0.7 GO:1902916 positive regulation of protein polyubiquitination(GO:1902916)
0.0 0.3 GO:0032423 regulation of mismatch repair(GO:0032423) negative regulation of Wnt signaling pathway involved in dorsal/ventral axis specification(GO:2000054)
0.0 0.3 GO:0086023 adrenergic receptor signaling pathway involved in heart process(GO:0086023)
0.0 0.2 GO:1904715 negative regulation of chaperone-mediated autophagy(GO:1904715)
0.0 1.0 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.0 0.9 GO:0033008 positive regulation of mast cell activation involved in immune response(GO:0033008) positive regulation of mast cell degranulation(GO:0043306)
0.0 0.2 GO:0000821 regulation of arginine metabolic process(GO:0000821)
0.0 0.2 GO:0019676 ammonia assimilation cycle(GO:0019676)
0.0 0.1 GO:0060671 epithelial cell differentiation involved in embryonic placenta development(GO:0060671) epithelial cell morphogenesis involved in placental branching(GO:0060672)
0.0 0.4 GO:0072307 metanephric nephron tubule epithelial cell differentiation(GO:0072257) regulation of metanephric nephron tubule epithelial cell differentiation(GO:0072307)
0.0 0.5 GO:0090557 establishment of endothelial intestinal barrier(GO:0090557)
0.0 0.2 GO:0002551 mast cell chemotaxis(GO:0002551) mast cell migration(GO:0097531)
0.0 0.4 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.0 0.6 GO:0046415 urate metabolic process(GO:0046415)
0.0 0.3 GO:0072553 terminal button organization(GO:0072553)
0.0 0.4 GO:1904424 regulation of GTP binding(GO:1904424)
0.0 0.4 GO:0006020 inositol metabolic process(GO:0006020)
0.0 1.3 GO:0097352 autophagosome maturation(GO:0097352)
0.0 0.2 GO:0070672 interleukin-15-mediated signaling pathway(GO:0035723) response to interleukin-15(GO:0070672) cellular response to interleukin-15(GO:0071350)
0.0 1.0 GO:0050951 sensory perception of temperature stimulus(GO:0050951)
0.0 0.2 GO:1904491 protein localization to ciliary transition zone(GO:1904491)
0.0 1.0 GO:0018345 protein palmitoylation(GO:0018345)
0.0 0.3 GO:0036309 protein localization to M-band(GO:0036309) protein localization to T-tubule(GO:0036371)
0.0 0.4 GO:2000507 positive regulation of energy homeostasis(GO:2000507)
0.0 2.0 GO:0060193 positive regulation of lipase activity(GO:0060193)
0.0 0.2 GO:0043435 response to corticotropin-releasing hormone(GO:0043435) cellular response to corticotropin-releasing hormone stimulus(GO:0071376)
0.0 0.4 GO:0002072 optic cup morphogenesis involved in camera-type eye development(GO:0002072)
0.0 0.1 GO:1903699 tarsal gland development(GO:1903699)
0.0 0.2 GO:0032488 Cdc42 protein signal transduction(GO:0032488)
0.0 0.7 GO:0030574 collagen catabolic process(GO:0030574)
0.0 0.1 GO:0048539 bone marrow development(GO:0048539)
0.0 0.3 GO:1900364 negative regulation of mRNA polyadenylation(GO:1900364)
0.0 0.7 GO:0051444 negative regulation of ubiquitin-protein transferase activity(GO:0051444)
0.0 0.6 GO:0031954 positive regulation of protein autophosphorylation(GO:0031954)
0.0 1.9 GO:0001954 positive regulation of cell-matrix adhesion(GO:0001954)
0.0 0.6 GO:0034063 stress granule assembly(GO:0034063)
0.0 0.1 GO:0002856 stimulatory C-type lectin receptor signaling pathway(GO:0002223) negative regulation of natural killer cell mediated immune response to tumor cell(GO:0002856) negative regulation of natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002859)
0.0 0.2 GO:0099590 neurotransmitter receptor internalization(GO:0099590)
0.0 0.1 GO:1990839 response to endothelin(GO:1990839)
0.0 0.2 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.0 0.2 GO:0007042 lysosomal lumen acidification(GO:0007042)
0.0 0.1 GO:0046726 positive regulation by virus of viral protein levels in host cell(GO:0046726)
0.0 0.4 GO:0050930 induction of positive chemotaxis(GO:0050930)
0.0 0.6 GO:0032743 positive regulation of interleukin-2 production(GO:0032743)
0.0 0.1 GO:0031860 telomeric 3' overhang formation(GO:0031860) negative regulation of telomere capping(GO:1904354)
0.0 0.6 GO:0032331 negative regulation of chondrocyte differentiation(GO:0032331)
0.0 0.8 GO:0014823 response to activity(GO:0014823)
0.0 0.2 GO:0090074 negative regulation of protein homodimerization activity(GO:0090074)
0.0 0.2 GO:0051151 negative regulation of smooth muscle cell differentiation(GO:0051151)
0.0 0.3 GO:1904707 positive regulation of vascular smooth muscle cell proliferation(GO:1904707)
0.0 0.4 GO:0070932 histone H3 deacetylation(GO:0070932)
0.0 0.3 GO:0031953 negative regulation of protein autophosphorylation(GO:0031953)
0.0 0.9 GO:0035458 cellular response to interferon-beta(GO:0035458)
0.0 0.7 GO:0042744 hydrogen peroxide catabolic process(GO:0042744)
0.0 0.6 GO:0030225 macrophage differentiation(GO:0030225)
0.0 1.5 GO:0006446 regulation of translational initiation(GO:0006446)
0.0 0.0 GO:0021997 neural plate axis specification(GO:0021997)
0.0 0.1 GO:0021993 initiation of neural tube closure(GO:0021993)
0.0 0.4 GO:0021957 corticospinal tract morphogenesis(GO:0021957)
0.0 1.0 GO:0007257 activation of JUN kinase activity(GO:0007257)
0.0 0.5 GO:0014912 negative regulation of smooth muscle cell migration(GO:0014912)
0.0 0.3 GO:0051292 nuclear pore complex assembly(GO:0051292)
0.0 0.4 GO:0031069 hair follicle morphogenesis(GO:0031069)
0.0 0.2 GO:0036006 response to macrophage colony-stimulating factor(GO:0036005) cellular response to macrophage colony-stimulating factor stimulus(GO:0036006)
0.0 0.2 GO:2001288 positive regulation of caveolin-mediated endocytosis(GO:2001288)
0.0 0.5 GO:0001921 positive regulation of receptor recycling(GO:0001921)
0.0 0.5 GO:0045662 negative regulation of myoblast differentiation(GO:0045662)
0.0 0.1 GO:1902683 regulation of receptor localization to synapse(GO:1902683)
0.0 0.0 GO:0006391 transcription initiation from mitochondrial promoter(GO:0006391)
0.0 0.1 GO:0035513 oxidative RNA demethylation(GO:0035513) oxidative single-stranded RNA demethylation(GO:0035553)
0.0 0.3 GO:0060644 mammary gland epithelial cell differentiation(GO:0060644)
0.0 0.1 GO:2000588 positive regulation of platelet-derived growth factor receptor-beta signaling pathway(GO:2000588)
0.0 0.2 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.0 0.2 GO:0060211 regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060211) positive regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060213)
0.0 0.1 GO:0030223 neutrophil differentiation(GO:0030223)
0.0 0.2 GO:0044154 histone H3-K14 acetylation(GO:0044154)
0.0 0.1 GO:0043129 surfactant homeostasis(GO:0043129)
0.0 0.1 GO:0002692 negative regulation of cellular extravasation(GO:0002692) negative regulation of neutrophil degranulation(GO:0043314) negative regulation of blood vessel remodeling(GO:0060313) negative regulation of neutrophil activation(GO:1902564)
0.0 0.1 GO:0030321 transepithelial chloride transport(GO:0030321)
0.0 0.2 GO:0070475 rRNA base methylation(GO:0070475)
0.0 0.3 GO:0097062 dendritic spine maintenance(GO:0097062)
0.0 0.1 GO:2000601 positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.0 0.1 GO:0034143 regulation of toll-like receptor 4 signaling pathway(GO:0034143)
0.0 0.3 GO:0030497 fatty acid elongation(GO:0030497) very long-chain fatty acid biosynthetic process(GO:0042761)
0.0 0.5 GO:0002089 lens morphogenesis in camera-type eye(GO:0002089)
0.0 0.4 GO:0010842 retina layer formation(GO:0010842)
0.0 0.1 GO:0010808 positive regulation of synaptic vesicle priming(GO:0010808) presynaptic dense core granule exocytosis(GO:0099525)
0.0 0.1 GO:0044268 multicellular organismal protein metabolic process(GO:0044268)
0.0 0.1 GO:2000254 regulation of male germ cell proliferation(GO:2000254)
0.0 0.2 GO:0007252 I-kappaB phosphorylation(GO:0007252)
0.0 0.0 GO:0043974 histone H3-K27 acetylation(GO:0043974) regulation of histone H3-K27 acetylation(GO:1901674) negative regulation of histone H3-K27 acetylation(GO:1901675)
0.0 0.2 GO:0045792 negative regulation of cell size(GO:0045792)
0.0 0.1 GO:1901509 regulation of endothelial tube morphogenesis(GO:1901509)
0.0 0.1 GO:0000042 protein targeting to Golgi(GO:0000042)
0.0 0.0 GO:1901856 negative regulation of cellular respiration(GO:1901856)
0.0 1.0 GO:0042446 hormone biosynthetic process(GO:0042446)
0.0 0.2 GO:0045725 positive regulation of glycogen biosynthetic process(GO:0045725)
0.0 0.8 GO:0006611 protein export from nucleus(GO:0006611)
0.0 0.0 GO:1900151 regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay(GO:1900151) positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay(GO:1900153)
0.0 0.1 GO:0006977 DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest(GO:0006977) signal transduction involved in mitotic G1 DNA damage checkpoint(GO:0072431) intracellular signal transduction involved in G1 DNA damage checkpoint(GO:1902400)
0.0 0.2 GO:0006490 oligosaccharide-lipid intermediate biosynthetic process(GO:0006490)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 2.9 GO:0005900 oncostatin-M receptor complex(GO:0005900)
0.5 2.9 GO:0031523 Myb complex(GO:0031523)
0.5 5.4 GO:0042613 MHC class II protein complex(GO:0042613)
0.4 1.8 GO:0032127 dense core granule membrane(GO:0032127)
0.4 1.1 GO:0035354 Toll-like receptor 1-Toll-like receptor 2 protein complex(GO:0035354)
0.4 1.1 GO:1990667 PCSK9-AnxA2 complex(GO:1990667)
0.3 2.4 GO:0098651 collagen type IV trimer(GO:0005587) network-forming collagen trimer(GO:0098642) collagen network(GO:0098645) basement membrane collagen trimer(GO:0098651)
0.3 1.7 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
0.3 1.5 GO:0031251 PAN complex(GO:0031251)
0.3 3.6 GO:0020005 symbiont-containing vacuole membrane(GO:0020005)
0.3 3.5 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.3 2.4 GO:0031265 CD95 death-inducing signaling complex(GO:0031265)
0.2 1.3 GO:0032437 cuticular plate(GO:0032437)
0.2 1.6 GO:0042825 TAP complex(GO:0042825)
0.2 0.6 GO:1990682 CSF1-CSF1R complex(GO:1990682)
0.1 0.4 GO:0042720 mitochondrial inner membrane peptidase complex(GO:0042720)
0.1 0.7 GO:0071953 elastic fiber(GO:0071953)
0.1 1.9 GO:0043657 host(GO:0018995) host cell part(GO:0033643) host cell(GO:0043657)
0.1 1.0 GO:0005577 fibrinogen complex(GO:0005577)
0.1 1.3 GO:0045098 type III intermediate filament(GO:0045098)
0.1 0.1 GO:0000125 PCAF complex(GO:0000125)
0.1 4.3 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.1 0.9 GO:0042567 insulin-like growth factor ternary complex(GO:0042567)
0.1 0.4 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.1 2.1 GO:0000145 exocyst(GO:0000145)
0.1 0.3 GO:0097169 AIM2 inflammasome complex(GO:0097169)
0.1 1.5 GO:0045180 basal cortex(GO:0045180)
0.1 0.7 GO:0033010 paranodal junction(GO:0033010)
0.1 1.6 GO:0005614 interstitial matrix(GO:0005614)
0.1 3.6 GO:0002102 podosome(GO:0002102)
0.1 3.3 GO:0016235 aggresome(GO:0016235)
0.1 3.3 GO:0008180 COP9 signalosome(GO:0008180)
0.1 0.4 GO:0097550 transcriptional preinitiation complex(GO:0097550)
0.1 0.3 GO:0005899 insulin receptor complex(GO:0005899)
0.1 0.6 GO:0002177 manchette(GO:0002177)
0.1 0.5 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
0.0 0.7 GO:0000138 Golgi trans cisterna(GO:0000138)
0.0 0.2 GO:0035976 AP1 complex(GO:0035976)
0.0 0.1 GO:0070435 Shc-EGFR complex(GO:0070435)
0.0 0.1 GO:0032156 septin cytoskeleton(GO:0032156)
0.0 1.1 GO:0032982 myosin filament(GO:0032982)
0.0 0.5 GO:0005796 Golgi lumen(GO:0005796)
0.0 1.5 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.0 0.4 GO:0000322 storage vacuole(GO:0000322)
0.0 2.3 GO:0032154 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 0.8 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.0 0.4 GO:0042382 paraspeckles(GO:0042382)
0.0 3.6 GO:0097517 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0 0.2 GO:0043293 apoptosome(GO:0043293)
0.0 0.4 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 0.5 GO:0030127 COPII vesicle coat(GO:0030127)
0.0 0.9 GO:0030057 desmosome(GO:0030057)
0.0 0.4 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.0 0.5 GO:0036056 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.0 0.2 GO:0031933 telomeric heterochromatin(GO:0031933)
0.0 0.3 GO:0001940 male pronucleus(GO:0001940)
0.0 0.2 GO:0097422 tubular endosome(GO:0097422)
0.0 0.6 GO:0030014 CCR4-NOT complex(GO:0030014)
0.0 0.8 GO:0033270 paranode region of axon(GO:0033270)
0.0 1.0 GO:0005669 transcription factor TFIID complex(GO:0005669)
0.0 0.8 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 1.8 GO:0016459 myosin complex(GO:0016459)
0.0 0.1 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.0 2.1 GO:0005882 intermediate filament(GO:0005882)
0.0 0.7 GO:0045334 clathrin-coated endocytic vesicle(GO:0045334)
0.0 0.3 GO:0090533 cation-transporting ATPase complex(GO:0090533)
0.0 1.8 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.0 0.6 GO:0000930 gamma-tubulin complex(GO:0000930)
0.0 0.4 GO:0071564 npBAF complex(GO:0071564)
0.0 0.2 GO:0008024 cyclin/CDK positive transcription elongation factor complex(GO:0008024)
0.0 3.2 GO:0031234 extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.0 0.1 GO:0030870 Mre11 complex(GO:0030870)
0.0 0.2 GO:0031931 TORC1 complex(GO:0031931)
0.0 1.2 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 0.2 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.0 0.7 GO:0044295 axonal growth cone(GO:0044295)
0.0 0.2 GO:0035631 CD40 receptor complex(GO:0035631)
0.0 0.2 GO:0044322 endoplasmic reticulum quality control compartment(GO:0044322)
0.0 0.3 GO:0090545 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.0 0.1 GO:0000815 ESCRT III complex(GO:0000815)
0.0 0.1 GO:0070820 tertiary granule(GO:0070820)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
2.3 7.0 GO:0008396 oxysterol 7-alpha-hydroxylase activity(GO:0008396)
1.4 4.3 GO:0030298 receptor signaling protein tyrosine kinase activator activity(GO:0030298) CCR1 chemokine receptor binding(GO:0031726)
1.0 2.9 GO:0004915 interleukin-6 receptor activity(GO:0004915) interleukin-6 binding(GO:0019981)
0.8 5.1 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
0.8 2.5 GO:0003858 3-hydroxybutyrate dehydrogenase activity(GO:0003858)
0.8 3.9 GO:0035478 chylomicron binding(GO:0035478)
0.7 4.2 GO:0042289 MHC class II protein binding(GO:0042289)
0.7 3.9 GO:0008269 JAK pathway signal transduction adaptor activity(GO:0008269)
0.5 1.5 GO:1990698 palmitoleoyltransferase activity(GO:1990698)
0.5 2.9 GO:0034988 Fc-gamma receptor I complex binding(GO:0034988)
0.4 1.6 GO:0043120 tumor necrosis factor binding(GO:0043120)
0.4 1.2 GO:0050354 glycerone kinase activity(GO:0004371) FAD-AMP lyase (cyclizing) activity(GO:0034012) triokinase activity(GO:0050354)
0.4 1.1 GO:0042497 triacyl lipopeptide binding(GO:0042497)
0.4 1.1 GO:0015433 peptide antigen-transporting ATPase activity(GO:0015433) tapasin binding(GO:0046980)
0.3 0.9 GO:0004962 endothelin receptor activity(GO:0004962)
0.3 0.9 GO:0015140 malate transmembrane transporter activity(GO:0015140)
0.3 1.1 GO:0004800 thyroxine 5'-deiodinase activity(GO:0004800)
0.3 1.3 GO:0005131 growth hormone receptor binding(GO:0005131)
0.2 0.7 GO:0019150 D-ribulokinase activity(GO:0019150)
0.2 1.9 GO:0047035 testosterone dehydrogenase (NAD+) activity(GO:0047035)
0.2 1.3 GO:1990254 keratin filament binding(GO:1990254)
0.2 0.6 GO:0005157 macrophage colony-stimulating factor receptor binding(GO:0005157)
0.2 0.7 GO:0097199 cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097199)
0.2 3.8 GO:0005527 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.2 2.2 GO:0004887 thyroid hormone receptor activity(GO:0004887)
0.2 2.8 GO:0015143 urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.2 1.5 GO:0001025 RNA polymerase III transcription factor binding(GO:0001025)
0.2 0.7 GO:0034739 histone deacetylase activity (H4-K16 specific)(GO:0034739)
0.2 0.7 GO:0046997 oxidoreductase activity, acting on the CH-NH group of donors, flavin as acceptor(GO:0046997)
0.2 2.4 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.1 1.2 GO:0052851 cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
0.1 0.4 GO:0004368 glycerol-3-phosphate dehydrogenase activity(GO:0004368) oxidoreductase activity, acting on the CH-OH group of donors, quinone or similar compound as acceptor(GO:0016901)
0.1 0.4 GO:0071820 N-box binding(GO:0071820)
0.1 1.5 GO:0001094 TFIID-class transcription factor binding(GO:0001094)
0.1 1.2 GO:0097642 calcitonin family receptor activity(GO:0097642)
0.1 1.1 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.1 0.4 GO:0038052 type 1 metabotropic glutamate receptor binding(GO:0031798) RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding(GO:0038052)
0.1 1.1 GO:0035033 histone deacetylase regulator activity(GO:0035033)
0.1 1.9 GO:0015093 ferrous iron transmembrane transporter activity(GO:0015093)
0.1 0.2 GO:0032129 histone deacetylase activity (H3-K9 specific)(GO:0032129) NAD-dependent histone deacetylase activity (H3-K9 specific)(GO:0046969)
0.1 0.5 GO:0046978 TAP1 binding(GO:0046978) TAP2 binding(GO:0046979)
0.1 1.1 GO:0019834 phospholipase A2 inhibitor activity(GO:0019834)
0.1 0.5 GO:0043532 angiostatin binding(GO:0043532)
0.1 0.7 GO:0003835 beta-galactoside alpha-2,6-sialyltransferase activity(GO:0003835)
0.1 0.5 GO:0047710 bis(5'-adenosyl)-triphosphatase activity(GO:0047710)
0.1 0.9 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.1 0.3 GO:0080023 3R-hydroxyacyl-CoA dehydratase activity(GO:0080023)
0.1 0.9 GO:0004768 stearoyl-CoA 9-desaturase activity(GO:0004768)
0.1 3.7 GO:0001968 fibronectin binding(GO:0001968)
0.1 1.9 GO:0032036 myosin heavy chain binding(GO:0032036)
0.1 0.6 GO:0071532 ankyrin repeat binding(GO:0071532)
0.1 2.4 GO:0070628 proteasome binding(GO:0070628)
0.1 0.5 GO:0070004 cysteine-type carboxypeptidase activity(GO:0016807) cysteine-type exopeptidase activity(GO:0070004)
0.1 0.6 GO:0004920 interleukin-10 receptor activity(GO:0004920)
0.1 0.4 GO:0004063 aryldialkylphosphatase activity(GO:0004063)
0.1 3.1 GO:0070330 aromatase activity(GO:0070330)
0.1 0.8 GO:0008440 inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440)
0.1 0.4 GO:0004925 prolactin receptor activity(GO:0004925)
0.1 0.6 GO:0019770 IgG receptor activity(GO:0019770)
0.1 0.4 GO:0033743 peptide-methionine (R)-S-oxide reductase activity(GO:0033743)
0.1 0.3 GO:0001512 dihydronicotinamide riboside quinone reductase activity(GO:0001512) melatonin binding(GO:1904408)
0.1 0.3 GO:0042284 sphingolipid delta-4 desaturase activity(GO:0042284)
0.1 1.5 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.1 0.3 GO:0051435 BH4 domain binding(GO:0051435)
0.1 0.6 GO:0008131 primary amine oxidase activity(GO:0008131)
0.1 0.7 GO:0031419 cobalamin binding(GO:0031419)
0.1 0.9 GO:0019855 calcium channel inhibitor activity(GO:0019855)
0.1 1.1 GO:0097493 structural molecule activity conferring elasticity(GO:0097493)
0.1 1.0 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.1 0.9 GO:0005041 low-density lipoprotein receptor activity(GO:0005041)
0.1 1.8 GO:0017166 vinculin binding(GO:0017166)
0.1 0.8 GO:0070097 delta-catenin binding(GO:0070097)
0.1 2.1 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.0 0.4 GO:0000268 peroxisome targeting sequence binding(GO:0000268)
0.0 0.7 GO:0031996 thioesterase binding(GO:0031996)
0.0 0.9 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.0 0.2 GO:0016778 diphosphotransferase activity(GO:0016778)
0.0 1.0 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.0 0.4 GO:0015288 porin activity(GO:0015288)
0.0 0.6 GO:0019957 C-C chemokine binding(GO:0019957)
0.0 0.9 GO:0005003 ephrin receptor activity(GO:0005003)
0.0 0.3 GO:0070579 methylcytosine dioxygenase activity(GO:0070579)
0.0 0.6 GO:0097153 cysteine-type endopeptidase activity involved in apoptotic process(GO:0097153)
0.0 0.2 GO:0034211 GTP-dependent protein kinase activity(GO:0034211)
0.0 0.1 GO:0045030 UTP-activated nucleotide receptor activity(GO:0045030)
0.0 0.2 GO:0000253 3-keto sterol reductase activity(GO:0000253)
0.0 0.4 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.0 0.4 GO:0016175 superoxide-generating NADPH oxidase activity(GO:0016175)
0.0 0.4 GO:0015217 ATP transmembrane transporter activity(GO:0005347) ADP transmembrane transporter activity(GO:0015217)
0.0 0.5 GO:0031702 type 1 angiotensin receptor binding(GO:0031702)
0.0 0.4 GO:0042609 CD4 receptor binding(GO:0042609)
0.0 0.6 GO:0030957 Tat protein binding(GO:0030957)
0.0 0.2 GO:0005095 GTPase inhibitor activity(GO:0005095)
0.0 0.2 GO:0016434 rRNA (cytosine) methyltransferase activity(GO:0016434)
0.0 2.0 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.0 1.7 GO:0051019 mitogen-activated protein kinase binding(GO:0051019)
0.0 0.3 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.0 0.2 GO:0032405 MutLalpha complex binding(GO:0032405)
0.0 0.9 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 0.3 GO:0098599 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.0 0.2 GO:0004351 glutamate decarboxylase activity(GO:0004351)
0.0 0.6 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 0.3 GO:0051525 NFAT protein binding(GO:0051525)
0.0 0.2 GO:0034452 dynactin binding(GO:0034452)
0.0 0.1 GO:0048408 epidermal growth factor binding(GO:0048408)
0.0 0.4 GO:0070008 serine-type exopeptidase activity(GO:0070008)
0.0 0.4 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.0 0.2 GO:0061629 RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629)
0.0 0.5 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 0.2 GO:0098519 nucleotide phosphatase activity, acting on free nucleotides(GO:0098519)
0.0 0.2 GO:0002135 CTP binding(GO:0002135)
0.0 0.4 GO:0044548 S100 protein binding(GO:0044548)
0.0 0.3 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.0 1.0 GO:0008536 Ran GTPase binding(GO:0008536)
0.0 1.0 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.0 0.7 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.0 0.4 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.1 GO:0046975 histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.0 0.2 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.0 0.1 GO:0001566 phorbol ester receptor activity(GO:0001565) non-kinase phorbol ester receptor activity(GO:0001566)
0.0 0.1 GO:0050436 microfibril binding(GO:0050436)
0.0 0.4 GO:0051787 misfolded protein binding(GO:0051787)
0.0 1.2 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.0 0.1 GO:0035515 oxidative RNA demethylase activity(GO:0035515)
0.0 0.3 GO:0070412 R-SMAD binding(GO:0070412)
0.0 0.3 GO:0008327 methyl-CpG binding(GO:0008327)
0.0 1.3 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0 0.2 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.0 0.3 GO:0070411 I-SMAD binding(GO:0070411)
0.0 0.6 GO:0003785 actin monomer binding(GO:0003785)
0.0 0.7 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.0 3.3 GO:0008236 serine-type peptidase activity(GO:0008236)
0.0 5.0 GO:0003924 GTPase activity(GO:0003924)
0.0 0.5 GO:0042605 peptide antigen binding(GO:0042605)
0.0 0.2 GO:0032051 clathrin light chain binding(GO:0032051)
0.0 0.5 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 0.1 GO:0034713 type I transforming growth factor beta receptor binding(GO:0034713)
0.0 0.4 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.0 0.3 GO:0070402 NADPH binding(GO:0070402)
0.0 0.3 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0 3.5 GO:0001047 core promoter binding(GO:0001047)
0.0 0.4 GO:0031435 mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.0 0.3 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.0 0.4 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 0.1 GO:0003989 acetyl-CoA carboxylase activity(GO:0003989)
0.0 0.1 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.0 0.3 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.0 0.5 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0 0.1 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.0 0.2 GO:0015174 basic amino acid transmembrane transporter activity(GO:0015174)
0.0 0.2 GO:0019871 sodium channel inhibitor activity(GO:0019871)
0.0 1.5 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.5 GO:0008307 structural constituent of muscle(GO:0008307)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 3.0 ST JAK STAT PATHWAY Jak-STAT Pathway
0.1 2.3 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.1 4.7 PID IL27 PATHWAY IL27-mediated signaling events
0.1 6.4 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.1 3.0 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.1 3.1 ST GA12 PATHWAY G alpha 12 Pathway
0.1 4.1 PID IL2 1PATHWAY IL2-mediated signaling events
0.1 3.3 PID CXCR3 PATHWAY CXCR3-mediated signaling events
0.1 2.3 PID IL23 PATHWAY IL23-mediated signaling events
0.1 2.4 PID IL12 2PATHWAY IL12-mediated signaling events
0.1 3.4 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.1 0.7 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.1 0.2 PID NFKAPPAB ATYPICAL PATHWAY Atypical NF-kappaB pathway
0.1 1.3 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.0 0.6 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 3.0 PID INTEGRIN3 PATHWAY Beta3 integrin cell surface interactions
0.0 0.4 ST PAC1 RECEPTOR PATHWAY PAC1 Receptor Pathway
0.0 2.0 PID PI3KCI PATHWAY Class I PI3K signaling events
0.0 4.9 PID REG GR PATHWAY Glucocorticoid receptor regulatory network
0.0 0.4 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.0 1.4 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.0 3.3 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.0 1.6 PID ALK1 PATHWAY ALK1 signaling events
0.0 2.7 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 2.0 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 3.1 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.0 1.2 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.0 0.9 PID AMB2 NEUTROPHILS PATHWAY amb2 Integrin signaling
0.0 1.5 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.0 1.3 PID ENDOTHELIN PATHWAY Endothelins
0.0 0.7 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.0 1.1 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 0.8 ST ERK1 ERK2 MAPK PATHWAY ERK1/ERK2 MAPK Pathway
0.0 0.4 PID PTP1B PATHWAY Signaling events mediated by PTP1B
0.0 0.1 SA B CELL RECEPTOR COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.0 0.4 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.0 0.7 PID TCR PATHWAY TCR signaling in naïve CD4+ T cells
0.0 3.3 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 1.2 PID RHOA REG PATHWAY Regulation of RhoA activity
0.0 0.9 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.0 0.4 SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES Genes related to the insulin receptor pathway
0.0 3.6 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 0.3 PID RETINOIC ACID PATHWAY Retinoic acid receptors-mediated signaling
0.0 0.4 PID RAC1 PATHWAY RAC1 signaling pathway
0.0 0.7 PID TELOMERASE PATHWAY Regulation of Telomerase

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 7.0 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.3 1.1 REACTOME BETA DEFENSINS Genes involved in Beta defensins
0.2 4.1 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.2 8.4 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.1 2.0 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.1 3.9 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.1 2.4 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.1 3.9 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.1 5.5 REACTOME GROWTH HORMONE RECEPTOR SIGNALING Genes involved in Growth hormone receptor signaling
0.1 3.8 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.1 1.3 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.1 0.2 REACTOME ACTIVATION OF NF KAPPAB IN B CELLS Genes involved in Activation of NF-kappaB in B Cells
0.1 5.0 REACTOME INTERFERON GAMMA SIGNALING Genes involved in Interferon gamma signaling
0.1 1.4 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.1 2.2 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.1 0.8 REACTOME NFKB ACTIVATION THROUGH FADD RIP1 PATHWAY MEDIATED BY CASPASE 8 AND10 Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
0.1 1.1 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.1 1.5 REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.0 2.8 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.0 1.0 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.0 1.5 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0 0.9 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 1.5 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.0 0.7 REACTOME ACTIVATION OF IRF3 IRF7 MEDIATED BY TBK1 IKK EPSILON Genes involved in Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon
0.0 0.7 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.0 0.4 REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
0.0 0.7 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.0 3.5 REACTOME MHC CLASS II ANTIGEN PRESENTATION Genes involved in MHC class II antigen presentation
0.0 0.4 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.0 1.0 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.0 0.4 REACTOME ERKS ARE INACTIVATED Genes involved in ERKs are inactivated
0.0 0.5 REACTOME HS GAG DEGRADATION Genes involved in HS-GAG degradation
0.0 0.9 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.0 1.0 REACTOME NOD1 2 SIGNALING PATHWAY Genes involved in NOD1/2 Signaling Pathway
0.0 0.7 REACTOME EGFR DOWNREGULATION Genes involved in EGFR downregulation
0.0 1.2 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.0 2.6 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 0.4 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.0 0.5 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0 0.5 REACTOME CD28 DEPENDENT PI3K AKT SIGNALING Genes involved in CD28 dependent PI3K/Akt signaling
0.0 0.2 REACTOME DSCAM INTERACTIONS Genes involved in DSCAM interactions
0.0 0.2 REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY Genes involved in Regulation of the Fanconi anemia pathway
0.0 1.3 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.0 0.5 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.0 0.8 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.0 0.4 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.0 0.9 REACTOME GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.0 0.1 REACTOME OLFACTORY SIGNALING PATHWAY Genes involved in Olfactory Signaling Pathway
0.0 0.4 REACTOME RNA POL III TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase III Transcription Termination
0.0 1.3 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.0 0.1 REACTOME SHC1 EVENTS IN EGFR SIGNALING Genes involved in SHC1 events in EGFR signaling
0.0 0.5 REACTOME G BETA GAMMA SIGNALLING THROUGH PI3KGAMMA Genes involved in G beta:gamma signalling through PI3Kgamma
0.0 0.6 REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.0 0.3 REACTOME MUSCLE CONTRACTION Genes involved in Muscle contraction
0.0 0.4 REACTOME SYNTHESIS OF PC Genes involved in Synthesis of PC
0.0 0.1 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.0 0.2 REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL Genes involved in AKT phosphorylates targets in the cytosol